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Food Nutrition Pharma Beauty, Bone & Joint COLLASIL ® The highest bioavailable soluble silicon

COLLASIL · 2020. 12. 20. · monomethylsilanetriol (MMST) forms have the optimal bioavailability1. The chemistry of these forms explains this result. OSA and MMST are not only organic

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  • Food Nutrition Pharma

    www.iontec-europe.com

    These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

    Beauty, Bone & Joint

    COLLASIL®The highest bioavailable

    soluble silicon

  • Blood

    Der

    mis

    Epid

    erm

    is

    SKIN

    Inte

    stin

    al w

    all

    Hydrogen bonds between silicon and

    collagen**

    Si SiAA

    AA AA

    A patented stabilization technology

    In Nature, di!erent chemical forms of silicon exist, which dictate its biological properties:

    mineral form (insoluble): quartz, emerald, etc. active form (water soluble): orthosilicic acid and monomethylsilanetriol

    Only water soluble silicon can be assimilated by the body and is biologically active. However, in high concentration, it polymerizes, becoming less instable and bioavailable.

    In the body, silicon is found in conjunctive tissues like bone, cartilage, skin, vessels, etc. with a concentration that decreases with aging.

    Silicon, the 2nd most abundant element on Earth

    STABILIZATION

    Technology

    PATENTED

    1Stabilization

    of the silicon with a peptidic matrix composed of hydrolyzed fish collagen

    Resistance Elasticity

    Better intestinal absorption of amino acids and the released silicon

    in the blood flow

    Skin architecture Creation of biological bonds that reinforce the

    skin integrity Stimulation of collagen production

    No silicon polymerization

    2 3

    Complex : Si + matrix*

    *Schematic representation of the complex** Schematic representation of the hydrogen bonds in the dermis between silicon and skin collagen

    SiAA

    AA AASi

    Stomach

    COLLASIL®OSA

  • A clinically proven bioavailability

    Quantity of silicon excreted in the urines in 24h after administrating the product

    Silicon presents di! erent absorption profi les, depending on its organic form.

    A clinical trial performed on 32 volunteers aged 19-40 years showed that the orthosilicic acid (OSA) and monomethylsilanetriol (MMST) forms have the optimal bioavailability1.

    The chemistry of these forms explains this result. OSA and MMST are not only organic but also monomeric, while the other forms show varying degrees of polymerization.

    Colloidal silica

    Magnesium trisilicate

    Orthosilicic acid (OSA)

    Choline-stabilized OSA

    Monomethylsilanetriol

    60

    40

    20

    0

    %

    1. Lassus, Journal of International Medical Research July-August 1993 vol. 21 no. 4 209-215 - 2. Barel, Arch Dermatol Res (2005) 297: 147–153 – 3. Bombonatti, AAD summer meeting, 2011 -4. Bone and Mineral Res., vol. 19, (2004), pp. 297-307 – 5. Ex vivo study on chondrocytes (1996) – 6. In vivo study on dogs after resection of the anterior cruciate ligament of the knee (1997)

    COLLASIL® health benefi ts

    Hair

    Nails

    Skin COLLASIL® OSA

    COLLASIL® MS HCALGOSIL®

    COLLASIL® OSAALGOSIL®

    COLLASIL® OSAALGOSIL®

    COLLASIL® OSAOSTEOSIL®

    Wrinkle reduction1................-36%Skin elasticity2......................+19%Skin resistance2...................+58%

    Anti-hair loss3......................+45%Growth3.................................+77%Brightness3..........................+86%Hair resistance1.....................+41%

    Nail resistance1....................+48%

    Positive connection between a silicon-rich diet and a high bone mineral density4

    Enzymatic activity inhibition of stromelysin and collagenase implied in cartilage degradation5

    Osteophytosis reduction6

    Bone & Joint

    Anti-agingArchitecture

    Firmness

    StrengthGrowth

    Brightness

    StrengthThickness

    Osteoarticular systemMobility

    Main benefi tsTissues Products Results of clinical studies

    1. Sripanyakorn S. et al., The comparative absorption of silicon from di! erent foods and food supplements, Br J Nutr. 2009 Sep; 102(6): 825–834.

  • WHY CHOOSE IONTEC SILICON ?

    High bioavailability

    Multiple proven beauty benefi ts

    www.iontec-europe.com

    These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

    Commercial Name

    COLLASIL®

    OSACOLLASIL®

    MS HCALGOSIL® OSTEOSIL®

    Orthosilic acid

    Monomethyl-silanetriol

    Monomethyl-silanetriol

    Monoalkylsila-netriol

    100 to 600 mg/day

    100 to 600 mg/day

    100 to 600 mg/day

    15 to 20 ml/day

    Marinecollagenpeptide

    Marinecollagenpeptide

    Mannuronicacid

    PhosphorusAssociation of phosphorus (bone building block) and silicon to bring silicon closer to the cartilage

    Tablets, coated tablets, capsules and shots

    Stabilizationmatrix

    Active compound form

    Recommendeddosage

    Applications

    Technical dataTHE

    HIGHESTBIOAVAILABLE

    of soluble silicon

    SO URCE