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This is the Hospital that Katie Needs.

CHILDREN'S HOSPITAL of PITTSBURGH FOUNDATION

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Capital Campaign Case for Support This hardbound children’s book was developed to launch the new Children’s Hospital of Pittsburgh $600 million case for support.

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This is the Hospital that Katie Needs.

DEDICATED TO THE PEOPLE WHO

CARE FOR CHILDREN’S

the world of a child who is very ill. She’s afraid because she’s in a strange place. She doesn’t know

what will happen next. Imagine how this child’s parents feel. They are consumed with worry and stress

because of what the future may hold. Think of the doctors and nurses called to help this child. They’re trained to respond

quickly and skillfully, but crowded conditions challenge their every move.This is the world of the current Children’s Hospital of Pittsburgh. Yet, despite

cramped patient rooms, a teeming Emergency Department, and limited research space,this hospital continues to offer world-class care, and achieve patient outcomes that areamong the best anywhere.

We are driven by this mission. Our vision of the future is simple. We will raise the bar—not only by enabling our brilliant clinicians and researchers to practice in anoutstanding facility but by making every child who comes through our doors feel more at ease, and every family more reassured.

But if we are to achieve our goals, there are needs that cannot be ignored. You canhelp expand our facilities and our horizons. With your generosity, Children’s Hospital ofPittsburgh will become one of the top five pediatric healthcare centers in the country—

a hospital that every child needs.

Stepinto

D

Dear Friends,

It has been continually rewarding to play a part in the tremendouswork done at Children’s Hospital of Pittsburgh. Children’s haslong been a leader in advancing pediatric medicine. In the 1950s,it was Jonas Salk’s miraculous polio vaccine. In the early 1980s,it was the start of the transplantation program that has performedmore pediatric organ and tissue transplants than any other center.

Through other pioneering treatments and research,children with cystic fibrosis, cancer, sickle cell disease and heartdefects have been able to live longer, fuller lives than anyoneever dreamed possible. And historic progress is being madetoward finding the cause and, thereby, a cure for juvenile diabetes.

Our medical capability has grown alongside our commitmentto the community. Families of the Pittsburgh region know thatChildren’s will never turn away a child in need.

This hospital has cared for generations of our children. As Children’s now faces several large and pressing issues—steadily increasing demand for care, rapidly outmoded facilities,and the explosive growth of research—we again are fortunate to play a part in helping Children’s take its next big step.

A

CARING FOR CHILDREN’S

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As you can see on the pages that follow, the new Children’sHospital of Pittsburgh will fuel excellence on every level.In addition, the new facilities will be a dynamic engine ofgrowth, adding $100 million annually to the region’s economyand creating more than 1,000 well-paying jobs.

This institution has proven to be a true benefit to ourregion. Thus the goal of raising $100 million for construction,clinical programs and research is clearly as wise an investment for western Pennsylvania today as it was when Children’s wasfounded in 1890.

The funds raised in this Capital Campaign will supplementsubstantial support from UPMC and Highmark, making thisthe legacy of an entire community.

Please join us in this most rewarding effort, and show thatyou, too, care for Children’s.

Sincerely,

C

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Edwin F. Scheetz Jr., Co-Chair

Mary Jo Howard Dively, Esq., Vice Chair

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Thomas G. Bigley, Co-Chair

Catharine M. Ryan, Incoming Chair

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Since its beginnings, Children’s Hospital of Pittsburgh

has depended upon the philanthropic generosity of the region.

This renowned hospital has cared for generations of our

children. Now, at this important moment, we must show that

we care for Children’s. Your generosity will help shape

Children’s Hospital for the next 100 years.

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Funding for the new Children’s

Hospital of Pittsburgh will come from

a variety of sources. UPMC has committed

more than 80 percent of the total campus

construction cost, and Highmark has

helped with site exploration costs and

site purchase. The Capital Campaign

of the Children’s Hospital of Pittsburgh

Foundation seeks to raise $100 million

to complete construction and to strengthen

the Foundation’s endowment, which

annually provides 5 percent of its value

to hospital programs and projects.

THE LEGACY OF AN ENTIRE COMMUNITY

Site SizeTotal Square Footage

Total BedsExpansion Beds

Critical Care BedsPrivate Rooms

Operating RoomsTransport Helipads

Emergency Exam RoomsResearch Lab Footage

Parking Spaces

10 acres1.5 million262477924613241300,0001,400

A LANDMARK CAMPUS

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$100 millionFoundation Capital Campaign Goal

$575 million budget for constructionUPMC

$68.6 million site exploration and purchaseHighmark

Imagine the possibilities. In the new

Children’s Hospital of Pittsburgh, there will

be room to grow and deliver the highest levels

of patient care.

For example, in the clinical services building,

families are immediately welcomed by clear and

simple directional signs, electronic message boards

and family gathering areas. A total of 262 beds,

virtually all in private rooms, will provide more

personalized care in a family-centered environment.

With nine floors, three parking garages and two

helipads, there will be ample room for everyone.

Technology ranging from wireless networking to

reconfigurable floor plans will ensure that Children’s

will embrace the future. This will be one of the

first paperless, digital pediatric hospitals, where

a child’s doctor can view the complete patient

chart from anywhere on campus and simultaneously

with other caregivers.

Careful thought has been given to locate units

and operations that frequently work together. For

example, the orthopaedic outpatient clinic will be

adjacent to the X-ray and imaging services. The cardiac

intensive care unit will be on the same floor as the

catheterization laboratories and the operating rooms.

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The new research building, with 300,000 square

feet of bright, high-tech lab space, has been expertly

designed to encourage collaboration. Conveniently

located adjacent to the clinical services building,

the research facility includes a 200-seat auditorium

with full teleconferencing ability and capacity for

70 researchers and their teams.

This will be one of the first pediatric healthcare

institutions to pursue the Leadership in Energy and

Environmental Design (LEED) 2.0 standards, joining

the wave of new “green” projects that are transforming

the Pittsburgh region. In constructing a new campus,

Children’s can take into consideration the direct and

indirect effects that buildings have on the health of

patients, families and staff. Through the use of nontoxic

materials, energy-efficient natural lighting and other

building techniques, we can cut our daily operating

costs while improving the impact on our internal and

external environments.

The new Children’s Hospital will be a tribute

to the extraordinary dedication and continual

accomplishments of its physicians and staff. But more

important, it will be a warm and welcoming place

for families—a place where exceptional care will be

skillfully delivered in an environment that makes

every child feel safe and comfortable.

A WARM WELCOME

Katie ProsserA P I C T U R E O F H E A L T H

Katie Prosser was diagnosed with a malignant brain tumor at the age of 15 months. Although there seemed little hope for a cure, Katie is the

picture of health today, thanks to Children’s Hospital of Pittsburgh. Katie’sdoctors followed her surgery with chemotherapy and intensity-modulatedradiation therapy—a new protocol that delivers high doses of radiation tothe tumor, while minimizing radiation to the healthy brain tissue. Katie was one of the youngest patients ever to be treated with thissophisticated therapy.

Now, at age 5, Katie is tumor-free, and her prognosis is excellent.“She doesn’t remember being sick,” says Katie’s mother, Valerie Prosser.“We could not have received better care anywhere.”

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This is the Room that Katie Needs.

Look around through

Katie’s eyes. What makes this place so special?

It feels more like home, rather than a hospital

room, with inviting colors and soft fabrics.

When Children’s Hospital of Pittsburgh

embarked on the development of a new facility,

we asked doctors, nurses, parents and also

children what they needed in a hospital.

Their answers inspired us. Bright colors,

beds set at age-friendly heights. Sleeping space

for parents who want to stay with their child.

Desks, data ports and so much more. Slowly, the

vision evolved, meshing the wish lists of patients

and their families with those of world-renowned

clinicians, nurses and researchers.

Each year, more than 12,000 patients are

admitted to Children’s Hospital of Pittsburgh.

They stay an average of five days in semiprivate

rooms designed to hold two patients. But often,

concerned parents and guardians stay by the

bedside for hours each day. While the family’s

involvement is a clear benefit, the crowding

can challenge caregivers’ ability to control

infection, ensure patient privacy and provide

other components of high-quality care.

In the new Children’s Hospital of Pittsburgh,

nearly every patient room, including those in

critical care units, will be private. Patients will

have more control over noise, lighting and room

temperature, and families will enjoy more options

for creating a sense of normalcy.

Inpatient rooms will have a standardized

staff zone, so that caregivers can easily acclimate to

the work processes. There will be more flexibility

in assigning beds and coordinating the number

of caregivers with the needs of patients.

Each 21-bed inpatient unit also will bring

caregivers closer to patients, thereby increasing

response times and decreasing the possibility of

error. With more room for patients, and greater

staff efficiency, the new Children’s will rise to meet

the needs—and the challenges—of the future.

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From a distance, we wanted children to say, ‘That’s my building!’ It was important that this new hospital be designed to convey a sense of welcoming—the fact that they havereached an important destination designed just for them. Upon entering the campus, we wanted all visitors—patients,families and staff—to feel uplifted and hopeful. The newChildren’s campus is meant to transform our patients from a state of illness to wellness.

ANDREW H. URBACH, MDAssistant Medical Director

for Clinical Excellence

A ROOM FULL OF COMFORT, CHEER AND KATIE’S BEARS.

David RoganR E A L H O P E

David’s story is miraculous. Struck by lightning at a family reunion,David did not respond to CPR. His heartbeat was restored during

the ambulance ride to the local hospital, and David was redirected toChildren’s Hospital of Pittsburgh. But there were severe complications.Testing showed profound deafness in both ears, and symptoms of a torndeep membrane.

Otolaryngologist Dr. David Mandell explained the uncertainties of surgery to David’s parents. “That’s one of the things that I find to bevery special at Children’s Hospital—we very carefully keep the family inthe loop,” he says.

David’s surgery was doubly successful. Not only did his cognitivefaculties return, but his hearing was restored as well.

“They’re just amazing at Children’s,” said David’s mother, Jenny.

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This is the Healing Garden thatDavid’s Family Needs.

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Everyonewho is sick needs a

hand to hold. But for children like David, the

need goes far beyond that.

That’s why, decades ago, Children’s

created one of the first family advisory councils

in pediatric healthcare. And why, today, we’re

building a campus with thoughtful amenities

throughout, and four times more space for

families than other pediatric centers.

Patients and their families can gather in

a 20,000-square-foot Resource Center and

Solarium that will serve as the hospital’s “town

square,” complete with classrooms, libraries,

a business center for working parents, and

a chapel for all faiths.

Activity rooms on every inpatient unit

will be designated “medical-free zones,” where

patients, parents and siblings can go to forget

illness for a while. A beautiful, 500-square-foot

rooftop Healing Garden will be available with

fresh air and flowers in the day and twinkling

lights at night.

This is a world away from the hospital’s

current condition. Today, physical limitations

can interfere with care. Because rooms are

crowded, families are not always able to provide

comfort and encouragement at their child’s

bedside. Caregivers must take time to find

parents and guardians for consultations or

to be present for their children’s procedures.

With the realization of the Lawrenceville

campus, Children’s will offer private rooms,

plus many opportunities for families to gather

together or to be alone. To work, learn, eat,

play and—ideally—stay strong.

We welcome the family as an integral part

of each patient’s healthcare team because we

know that they not only provide a valuable

link between child and caregivers, they also

impart a special brand of support that cannot

come from anyone else.

When we help a family cope with their

child’s illness, the family is better able to help

us care for their child.

Communication is the most important thing we do. It’s important to listen to what the patient and parents aretelling you, and then to pursue data, in part, by asking the rightquestions. We also try to put ourselves in the shoes of the parents.We recognize that an emergency room is not where they wantto be, but we want their perception of the experience to be as good as it can be.

RICHARD A. SALADINO, MDChief, Pediatric Emergency Medicine

A HEALING GARDEN TO RESTORE SPIRITS.

Matthew RickettsF A S T S A V E

The chances of Matthew recovering from near-fatal brain injuries sufferedin a car crash were slim. But thanks to the expertise of a multidisciplinary

trauma team at Children’s Hospital, the teen’s outcome was good.The car Matthew was riding in ran up an embankment and flipped

over. Matthew’s blood pressure was undetectable, and he was not able to take oxygen into his badly damaged lungs. Matthew was in danger ofbleeding to death. With his brain swelling, he slipped into a coma.

Surgeon Edward M. Barksdale Jr., MD, repaired Matthew’s lung, andthe brain swelling began to subside. Within a month, Matthew awoke fromhis coma and quickly recovered. He returned to high school for his senioryear and played a starring role on his high school soccer team.

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This is the Care that Matthew Needs.

Howwould you feel if your child had

a serious head injury and was being rushed to

the hospital? You would want the best medical

team, the best technology, and the best chance

for a positive outcome.

In 2006, nearly 60,000 children passed

through Children’s emergency room, and 1,700

patients were admitted to the Benedum Pediatric

Trauma Program. With the busiest pediatric

trauma center in the country, the largest pediatric

transplantation institute anywhere, and leading

centers for the treatment of diabetes, cystic

fibrosis and other childhood illnesses, we already

enjoy a reputation for outstanding clinical care.

And we are vitally poised for future growth.

Thanks to new technology, scientific research

and a team of forward-thinking physician-scientists,

Children’s Hospital of Pittsburgh is prepared

to forge ahead to make caring for children gentler,

less invasive and far more effective.

The only barrier that currently exists to

attracting and retaining world-class physicians

and scientists is the need for more laboratory

and clinical space.

Some of the new centers envisioned at

Children’s include:

Comprehensive Fetal Intervention Center

to address congenital problems detected in utero

by obstetrician-gynecologists

Comprehensive Intestinal Care Center

that will make possible more successful intestine

transplants in very small children

Cell Transplantation Center that will treat

muscle, bone and organ diseases

Pediatric Surgery Center that is state-of-

the-art, with minimally invasive surgical suites

and three-dimensional imaging technology

Pediatric Diagnostic Referral Center, with

a larger team of “super-diagnosticians” who will

address the most complex pediatric problems

When the new Children’s is complete, we

will achieve the vision of a pediatric hospital

that is—and will remain—one of the very best

in the country.

T

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Children’s is one of a few hospitals in the country that hasunited a well-established clinical program with an equally richresearch agenda. The collaboration between the hospital and theUniversity of Pittsburgh has been strong for generations. In thisenvironment and with the capacity of a new campus, I can seepediatric surgery forging even closer alliances with areas suchas transplantation, robotics and tissue engineering to developinnovative therapies for children.

GEORGE K. GITTES, MDChief, Department of Pediatric

Surgery, Surgeon-in-Chief

THE BEST POSSIBLE CARE MADE EVEN BETTER.

Jakob JasinA N E W B E G I N N I N G

Jakob Jasin was born with Maple Syrup Urine Disease (MSUD), a metabolicdisease that causes amino acids to accumulate in the body. The toxic effectcan lead to brain swelling, neurological damage and death.

During his first four years, Jakob’s metabolism was somewhat controlledby an extremely regimented diet free of protein with amino acids. Unlikemost kids, Jakob was not able to eat meat or dairy products. He had never tasted ice cream.

Despite his diet, Jakob continued to suffer approximately three metaboliccrises a year. Even something as simple as a cold could lead to brain swelling.The Jasins were led to Children’s Hospital of Pittsburgh, where experts recommended a liver transplant.

Since the successful transplant, Jakob can eat a regular diet, and hisamino acid levels have remained normal. His family gained peace of mind,and other children with MSUD gained a new method of cure.

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This is the Research that Jakob Needs.

2

Let’sput research under a microscope.

Let’s examine the quality and quantity of medical

breakthroughs that affect children like Jakob.

By any measure, Children’s Hospital of Pittsburgh

stands out as a leader.

Because we focus the best scientific minds on

some of the most devastating pediatric healthcare

problems, Children’s consistently develops new

treatments and cures that affect hundreds of

thousands of children annually, well beyond the

borders of western Pennsylvania.

Right now, scientists at Children’s are working

on cures in the next decade for type 1 diabetes,

cystic fibrosis, juvenile rheumatoid arthritis and

Duchenne muscular dystrophy.

They are developing gene therapies that will

keep some of the most delicate premature infants

alive and growing normally. They are formulating

vaccines to prevent common and often deadly

lung infections in children with HIV. They are

dramatically improving the lives of young

transplant patients, helping them survive

longer than before—and with less need than

ever for harmful antirejection drugs.

They are studying how to prevent allergies,

and how to improve outcomes for a wide range of

pediatric conditions, from otitis media (middle

ear infection) to pediatric cancer.

In spite of extremely limited laboratory space,

researchers at Children’s Hospital of Pittsburgh

conduct twice the volume of research per square

foot than the national average. Expanding research

programs have triggered a frequent refrain

from productive investigators: “I desperately

want to recruit more people, but there is nowhere

to put them.”

Imagine the new levels of research that will

be possible in the new Children’s—with even more

dedicated scientists, more laboratory facilities and

truly cutting-edge, sophisticated technology.

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For children whose livers are damaged by diseases and cancer,transplantation currently is the only option, but sometimes the waitfor an organ is too long. Our team is working on a mechanical support system—like dialysis for the liver—as a bridge to transplantation.But the best long-term hope, I believe, is our research into creatinghealthy liver cells from the patient’s own stem cells, ideally to help the liver repair itself.

GEORGE V. MAZARIEGOS, MDDirector, Hillman Center for

Pediatric Transplantation

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WHERE PHYSICIAN-SCIENTISTS WILL DEVELOP TOMORROW’S THERAPIES.

Amazing breakthroughs are

on the horizon. When completed, the new

300,000-square-foot John G. Rangos Sr. Research

Center at Children’s Hospital of Pittsburgh will

be one of the best-designed and most impressive

medical research laboratories in the country.

The result will be an environment that fosters

ingenuity and collaboration.

Better yet, it will bring together multidisci-

plinary teams of researchers to tackle the diseases

of childhood in new, more comprehensive ways.

With 75 percent more laboratory space than

the current facility, and with some of the most

advanced medical research tools, the new center

will enable Children’s to grow its federal research

funding to more than $50 million. An estimated

70 principal investigators and their teams will

work in the new center.

Designed by one of the foremost developers

of scientific laboratories in the United States,

with input from Children’s researchers, the new

center will maximize working laboratory space.

Five of the ten stories will be dedicated,

28,000-square-foot lab floors. Each will

have open work areas and a convenient conference

room to encourage cross-disciplinary research

and cooperation. Teams will be able to reconfigure

easily. Other floors will house a core of exciting

services available to all Children’s researchers:

apparatus for high-tech imaging, flow cytometry

and ex vivo cellular manipulation, to name a few.

Because the frontiers of pediatric

research are global as well as local, the hub

of the building will be a state-of-the-art

conference center. Two flexible meeting rooms

will adjoin an auditorium with moveable

seating for 200. All will be equipped with

an audiovisual and teleconferencing system

to enable the most productive presentations

and symposia.

This new research center will provide the

ideal environment to support the tremendous

research talent at Children’s today—and to

attract even more innovative thinkers to

Children’s Hospital in the years to come.

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Given the talent, ingenuity and enthusiasm of our researchers and their laboratoryteams, there is no reason that we cannot be one of the top five programs for pediatricresearch in the country. On the new Children’s campus, there will be room to fast-trackour most important studies.

We will be able to recruit researchers whose promising ideas can be explored. We caninvest in the technology that helps us move quickly from the laboratory bench to the bedside.

In addition, we will enable the cross-disciplinary collaboration that generates newtests, treatments and cures. And because many of Children’s programs are approved tooffer experimental treatments to today’s patients, we can be a destination of hope forfamilies from around the world.

DAVID H. PERLMUTTER, MDPhysician-in-Chief and Scientific Director

AN ENVIRONMENT THAT FOSTERS INNOVATION AND COLLABORATION.

We’re very interested in understanding how certain enzymesbreak down dietary fats so they can be absorbed, and howthis affects digestion and disease. What we’re learning will open doors to new therapies for acute pancreatitis, better ways to feed chronically ill infants, and more effective appetite and weight control.

““MARK E. LOWE, MD, PHDChief of Pediatric Gastroenterology

Our goal at Children’s is twofold—to search for the cause of juvenilerheumatoid arthritis, while recruiting some of the best researchersand clinicians to pave the way to more effective therapies. Everythingwe do is really focused on how to apply our understanding towardbetter outcomes for our patients.

RAPHAEL HIRSCH, MDChief of Pediatric Rheumatology

We are developing a program focused on lung immunologyand host defense to address the fact that, worldwide, respiratoryinfections are the No.1 killer of children. As we investigate genetherapies and new vaccines, we’ll be able to help doctors aroundthe world win the battle against viral and bacterial infections of the lungs.

JAY K. KOLLS, MDChief of Pediatric Pulmonology

Curing type 1 diabetes is more than a theoretical possibility. It’s anachievable goal that becomes closer with each discovery in the lab.We’re very excited because we are about to begin groundbreakingclinical trials to see if the treatments that were so effective on animalswill work in patients. A diagnosis of type1 diabetes can be devastatingfor children and their families. We hope this trial will have resultsthat are life-altering for patients who suffer from the disease.

MASSIMO M. TRUCCO, MDChief of Immunogenetics

Thebest and the brightest

pediatric medical professionals are

attracted here.

Today Children’s Hospital of Pittsburgh’s

residency program trains nearly 80 percent of

the pediatricians and pediatric specialists who

practice in the tristate region. It is not only

a rich and sought-after training ground, it is

one of the top 10 recipients of funding from

the prestigious National Institutes of Health.

Few pediatric healthcare centers are able

to offer robust fellowship programs in such

much-needed areas as pediatric rheumatology,

pulmonary medicine, gastroenterology, neuro-

surgery and otolaryngology. These fellowships

train approximately 70 specialists and

researchers each year.

Nearly 200 full-time faculty at Children’s

serve as teachers and mentors not only to

the pediatric residents and fellows, but also

to the students of the University of Pittsburgh

School of Medicine.

What’s more, our excellent clinical

outcomes owe a great deal of their success

to our outstanding nursing staff. Despite

a severe nationwide nursing shortage,

Children’s has been successful in its recruiting.

We are developing innovative programs for

nurse training and career development—

including paths in nursing research—to help

guarantee a continued competitive edge in

future recruitment.

These medical professionals, along with

recruited physician-researchers from renowned

medical institutions, embody a wealth of talent

and resources that is difficult to duplicate.

In combination with our advanced-design

clinical and research facilities, these experts will

extend the reputation of Children’s Hospital

around the country—and around the world.

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Taking care of children requires tuning in to a child’sdevelopmental level and involving the family in care and the healing process. If a nurse is looking for peers who are dedicated to nursing, an administration that embraces medical technology, and a chance to use the latest medicaladvances, Children’s Hospital of Pittsburgh is the best place to be.

DIANE S. HUPP, RN, MSNChief Nursing Officer

These are the Caregivers thatthe Children Need.

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There’s nothing more satisfying than helping a fellow pediatricianor primary care physician find the most appropriate care for ayoung patient. We offer a resource that is, frankly, quite uncommon.Our Diagnostic Referral Service allows physicians to tap into ourknowledge base and gain rapid access to a complete range ofservices within Children’s.

““

BASIL J. ZITELLI, MDChief of Diagnostic Referral Service

As one of the first hospitals in the nation to establish a weight management and wellness program, our mission is to help children andtheir families achieve and maintain healthy behaviors for a lifetime. Asthe waistlines of America’s youth keep expanding, our goal is to helpchildren avoid the complications associated with obesity. We strive to advance our understanding of childhood obesity through research andnew developments.

SILVA A. ARSLANIAN, MDDirector, Weight Management and Wellness Center

In critical care, we are bringing the laboratory to the bedside. This mix of complex, incredibly interesting medicine and the opportunity to connect with families and support them at such an important time is an amazing privilege. What else in the world could be as satisfying?

ANN E. THOMPSON, MDDirector of Critical Care Medicine

The concept that a child can have major kidney, bladder or genital reconstruction and essentially have no scars is the standard of care at Children’s. We’re one of only a few centers in the world to provide this state-of-the-art care.

STEVEN G. DOCIMO, MD, PHDChief of Pediatric Urology

It’s exciting to work in an environment that fosters so much creativityand has access to such cutting-edge technology. We’re one of only a few pediatric centers in the country, for example, that has successfullyimplanted an experimental, child-size artificial heart that keepsyoung patients alive while awaiting a heart transplant. Knowing our work makes a difference for these kids and their families is truly rewarding.

VICTOR O. MORELL, MDChief of Cardiothoracic Surgery

THE MOST ADVANCED TRAINING GROUND FOR THE FUTURE.

Training Clinical Specialists at Children’s Hospital of Pittsburgh

Residents

Fellows

Totals

2003 2004 2005 2006

116 118 126 143

47 55 66 70

163 173 192 213

T

Consider this future: By 2010,

Children’s Hospital of Pittsburgh has become one

of the nation’s top five pediatric healthcare centers.

Already ranked among the country’s best

pediatric hospitals by U.S. News & World Report,

the Children’s of the future has broadened its

scope even further to provide some of the most

innovative and effective clinical programs; garners

more than $50 million annually in National

Institutes of Health research funding; and offers

the most competitive pediatric physician training

in the country.

Children’s Hospital of Pittsburgh also

has become one of the best places to work for

pediatric clinicians, researchers, educators, nurses

and other caregivers. As one of the first pediatric

healthcare centers to meet Leadership in Energy

and Environmental Design (LEED) standards,

it can operate more efficiently, and can truly

embody our mission of providing a healthy,

stress-free environment that facilitates maximum

patient safety, and stimulates the best practices

in pediatric healthcare.

The new Children’s serves as a strong economic

engine, fueling the region’s economy with more

than 1,000 high-paying jobs and a steady stream

of revenue. Within the last year, hospital operations

directly or indirectly created more than 5,400

jobs in the state, and generated $25 million in

state tax revenue.

All told, Children’s infuses more than $671

million into the Pennsylvania economy, and that

includes more than $127 million from out-of-state

patients and visitors.

In Lawrenceville, home of Children’s 10-acre

campus, a once-vibrant city neighborhood has

returned to life in response to the influx of

3,000 employees, the many professionals attending

research and educational functions, and the

150,000 patients, families and visitors.

The benefits of the new Children’s Hospital

of Pittsburgh will be many—an anchor in its

city neighborhood, a jewel in our region and

an unsurpassed resource for healthcare providers

across the country and around the world.

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This is the Hospital that Pittsburgh Needs.

Many of these jobs require a bachelor’s and advanced degrees, helping the region retain itsbrainpower and leveraging the presence of our many colleges and universities. Taxes created as a resultof Children’s payroll will have a positive impact. In fact, spending in the state’s economy and thegeneration of fresh revenue from outside the state equaled $24.5 million in 2003. According tothe study, the new Children’s ongoing effect on the economy will be statewide.

JOBS

Further, one of the most interesting possibilities is the commercialization of research.Already, Children’s has highly specialized labs that perform analyses or create products such as“knockout” models, whose genes are modified to fit any number of traits under study. Researchersworldwide in need of these specialty services can and do include Children’s as a study subcontractor.

Beyond the direct-to-lab customers, it is possible that new discoveries could be spun off to companies such as those that specialize in biotech, precision instrumentation, software or pharmaceuticals. Anywhere from 370 to 800 full-time-equivalent jobs could be generated within five years by Children’s research efforts, either at new or existing companies.

AN ECONOMIC ENGINE

The building of a new healthcare campus for Children’s Hospital of Pittsburgh is currently the third largest construction project in the region. In November 2003, Children’s Hospital ofPittsburgh commissioned Tripp Umbach Healthcare Consulting, Inc., to study the hospital’s current and projected impact on the economy.

The construction stage will last through 2008 and have a statewide economic impact of $777 million, including nearly 3,300 direct and indirect construction jobs in Allegheny County.

Yet construction is just the beginning. When the hospital begins operation in 2009, we can expect:

New direct full-time-equivalents 791 New indirect full-time-equivalents 1,423

ANNUAL ECONOMIC IMPACTS

COMMERCIALIZATION OF RESEARCH

Annual out-of-state revenue $127 million

Annual statewide impact $671 million

Including:

Allegheny County $318.9 million

City of Pittsburgh $175.0 million

Lawrenceville/Bloomfield $24.5 million

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For over 50 years, I have been honored to serve as a trustee andtrustee emeritus of Children’s Hospital. This half century has been a period of remarkable advances in caring for children. During thistime, this internationally renowned hospital has attracted some ofthe most brilliant minds in pediatric clinical care and research.Now, we have a rare opportunity to ensure that the dedicated doctors, researchers, nurses and hospital staff have our supportwith state-of-the-art facilities to continue their critical work. Our children and our future depend upon it.

HENRY L. HILLMANChairman, Hillman Foundation and Henry L. Hillman Foundation

Throughout its existence, Children’s has raised the standardof pediatric medicine. The staff has translated their discoveries into improvements in the care of many childhood diseases, includingasthma, diabetes and obesity. Children’s does not just save the lives of sick children—it works to improve the lives of all children in our community.

“YVONNE COOK

President, Highmark FoundationVice President, Highmark Community and Health Initiatives

In a town of hardworking people, the staff of Children’s Hospital of Pittsburgh do some of the hardest work of all, and they areamong the best in the country. Everyone in our organizationbelieves that this world-class care should be there for every childwho needs it, and the new campus will ensure this access now, and for the next one hundred years.

“JAMES S. BROADHURSTChairman & CEO, Eat’n Park Hospitality Group

Without a doubt, the new Children’s Hospital of Pittsburgh is a resource for the whole region, but its leaders also share the vision of a revitalized Lawrenceville. We warmly welcomeChildren’s to our historic neighborhood, and we anticipate many mutual benefits for the institution and the community.

“KATE TRIMBLEExecutive Director, Lawrenceville Corporation

Our children will only grow up great if we are willing to providethem the best foundation. Good health is a key building block ofthat foundation, and that’s why we must support the new Children’sHospital of Pittsburgh. The hospital’s commitment to children’s healthand its expertise on many fronts are critical in the drive to betterprepare the next generation for school and life.

“JAMES E. ROHR

Chairman & CEO, PNC Financial Services Group, Inc.

Children’s Hospital of Pittsburgh has shownits leadership in many remarkable ways:

A pediatric trauma program that is one of the busiest in the country, admittingalmost 1,700 children in 2006 alone

The first Diagnostic Referral Service,created as a resource for pediatricianseverywhere who struggle to diagnosechildren with complicated illnesses

One of the world’s first programs for pediatric otolaryngology to improvetreatment of some of childhood’s mostcommon illnesses

The country’s first pediatric transplantation center, which continuesto achieve survival rates significantly higherthan national averages—across all types of transplants

The region’s only pediatric CardiacIntensive Care Unit (CICU), equipped tocare for the toughest medical conditionsthat compromise young hearts

An extensive research program that isamong the top 10 pediatric hospitals byshare of National Institutes of Health awards

A Residency in Pediatrics programthat trains nearly 80 percent of the pediatricians and pediatric specialistswho practice in the tristate region

One of the first pediatric hospitals to embrace computerized provider orderentry, a nationally recognized standardfor improving patient safety

Consistently ranked by U.S. News & World Report among the best pediatrichospitals in the country

SECURING OUR PLACE

IN THE WORLD

CAPITAL CAMPAIGN GOAL: $100 MILLION

NEW CAMPUS BUILDINGS: $50 MILLION

Each building of the new campus will integrate the best thinking on environments for children,families and healthcare workers. Infrastructure will encourage collaboration and will be modular—to meet our needs for the next 100 years. The 10-acre campus will comprise:

ADVANCED CLINICAL PROGRAMS: $25 MILLION

Within three to five years, Children’s has the potential to create and expand clinicalprograms that will set international standards—centers of excellence that will incorporatethe latest technology and research findings to help shape a new era in pediatrichealthcare. Among the centers envisioned:

NEW AND EXPANDED RESEARCH PROGRAMS: $25 MILLION

Our research funding, which includes significant support from the National Institutesof Health, will have more than doubled to $50 million by 2009. Combined with ourlandmark facility, this will enable Children’s to attract even more talented and respectedresearchers. With additional funds, we can implement an institute model within ourresearch program, where the focus would be on the most high-impact, novel ideas,especially in the promising realm of molecular and cellular research. This model wouldreward the pursuit of new developments, and would free successful principal investigatorsto concentrate directly on research. Areas in which Children’s has unique advantagescan be expanded into national resources such as:

Comprehensive Fetal Intervention Center

Comprehensive Intestinal Care Center

Hillman Center for PediatricTransplantation

National Pediatric Diagnostic Center

Weight Management and Wellness Center

Minimally Invasive Pediatric Surgery Center

The Center for Childhood Cancer Research

The Vaccine Research Center

The Center for the Study of Genetic Modifiers

The Fragile X Syndrome Center

Clinical Services Building—a nine-story hospital with 262 beds

John G. Rangos Sr. Research Center—a 10-story lab with room for 70 research teams

Mid-Site Garage and Terrace Garden

Family Residence Building withfitness and daycare centers

Medical and AdministrativeOffice Building

Campus Mechanical Equipment Building

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BOARD OF TRUSTEES

2006-2007 CHILDREN’S HOSPITAL OF PITTSBURGH

Mary Jo Howard Dively, Esq.Chair

Vincent C. Deluzio, Esq.Vice Chair

Howard W. Hanna IIIVice Chair

Roger A. OxendalePresident

Lorina W. Wise, Esq.Secretary

Mark J. GiaquintoTreasurer

Jeffrey S. BroadhurstLawrence J. Butler, MD*Chief Justice Ralph J. CappyRonald R. Davenport Jr. Robert A. DeMichieiDouglas P. DickWilliam F. Donaldson, MDGeorge K. Gittes, MD*Lawrence N. GumbergMartha Hartle Munsch, Esq.Robert M. HernandezMark J. LaskowArthur S. Levine, MDDavid H. Perlmutter, MD*John G. Rangos Sr.

Jeffrey A. RomoffCatharine M. RyanEdwin F. Scheetz Jr.Joseph C. Walton

HONORARY MEMBERS

Virginia W. AhlbrandtRobert L. Becker Jr.James S. BroadhurstMargaret ChildsHelen S. Faison, PhDHenry L. HillmanStephanie F. MallingerJean A. RobinsonMason Walsh Jr.

FOUNDATION TRUSTEES

Catharine M. RyanChair

Mary Jo Howard Dively, Esq.Vice Chair

Joseph C. WaltonInterim President

Jodi K. Innocent, Esq.Secretary

Bernadette M. ScheidTreasurer

Thomas G. BigleyLeslie W. Braksick, PhDRebecca Cost SnyderVincent C. Deluzio, Esq.Douglas P. DickWilliam F. Donaldson, MDHelen S. Faison, PhDLawrence N. GumbergHoward W. Hanna IIIMartha Hartle Munsch, Esq.

William H. IslerArthur S. Levine, MDRoger A. Oxendale*Janet F. PalumboDenise M. Pampena, Esq.David H. Perlmutter, MD*John G. Rangos Sr.Edwin F. Scheetz Jr.Ronald L. Violi

NEW HOSPITAL CAPITAL CAMPAIGN CABINET

Thomas G. BigleyLeslie W. Braksick, PhD Mary Jo Howard Dively, Esq.

Howard W. Hanna IIIDeAnn Aston MarshallRoger A. OxendaleDenise M. Pampena, Esq.

Catharine M. RyanEdwin F. Scheetz Jr.Joseph C. Walton

* ex officio

To Our Caring Benefactors,

Pittsburgh has not built its reputation by doing things in a small way. Fromour role in steel and manufacturing, to our breakthroughs in technology andbiomedicine, we have demonstrated our ability to pull together, and ouraccomplishments are world-scale. Today, we have the opportunity to fulfilla desperate need and, in doing so, achieve the next great triumph for this region.

Our need for a new children’s hospital is a once-in-our-lifetime opportunity. We already have in place the region’s commitment to healthcareas an industry, a wealth of educational and research resources, and cutting-edgetechnology. And as always, Children’s continues on a daily basis to save livesand to generously provide the best care to our region’s children, regardlessof their means.

All of it has been proven: now we have a chance to create one of the top pediatric care centers in the world—the Children’s Hospital of the future.

As the region’s only dedicated pediatric institution, Children’s constantpush for excellence—to improve care and find cures through research—isenhanced by our partnerships with UPMC and the University of Pittsburgh.

The foresight of our early leaders has been confirmed: a dedicated children’s hospital is a sound regional investment. And it is the right thing to do.

Right now, we have the power to expand the reach, the resources and thereputation of Children’s Hospital of Pittsburgh. I urge you to join us. Together we can plan the future of healthcare for generations to come, and give the childrena legacy of the best care in the world.

A TREASURE FOR THE REGION, A RESOURCE FOR THE WORLD

Sincerely,

Roger A. OxendalePresident and Chief Executive Officer

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Acknowledgements:Photography: Mark Bolster, David A. DeNoma, Ric Evans, Bill Exler, Ronald Fontana, Jonas Photography,

Kathryn Komperda, Lisa Kyle, Annie O'Neill, LeonWinkowski, Jason Yurkovich. Retouching by Mark Sherer.All architectural renderings by Astorino©2006. Illustrations by Dave Klug©2006.

Neighborhood photos by Tim Fabian©2006 (Courtesy of PPND). ©2006 Children’s Hospital of Pittsburgh Foundation, Pittsburgh, PA. All rights reserved.

1251 Waterfront Drive, Floor 5 • Pittsburgh PA 15222-4209

1-877-CHP-GIVE (1-877-247- 4483)