1997 benzofuran derivatives

benzofuran derivativesR 0070

34 - 118Implication and Improvement of Stereoselective Methylenation of aChiral Aldehyde Related to Total Synthesis of the Furaquinocins.— It is found that the aldehyde (I) can be methylenated with excellentstereoselectivity using the (S)-ylide (IIa). In contrast, with the corresponding(R)-ylide (IIb) moderate selectivity is observed. The epoxide (III) is a versatileintermediate in the synthesis of furaquinocins. — (SAITO, T.; SUZUKI, T.;TAKEUCHI, K.; MATSUMOTO, T.; SUZUKI, K.; Tetrahedron Lett. 38 (1997)21, 3755-3758; Dep. Chem. Eng., Tokyo Inst. Technol., Meguro, Tokyo 152,Japan; EN)

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