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7/29/2019 Ch 57 - Anxiety Disorder.pptx
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ANXIETY DISORDER
Jeny Rose Quiblat, MD
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ANXIETY
Fearful emotion accompanied by certain physicalsymptoms
perceived as a subjective feeling of heightenedtension and diffuse uneasiness
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SUBCLASSESOF ANXIETY DISORDER
Panic Disorder
Phobic
obsessive-compulsive
Generalized anxiety disorder post-traumatic stress
social phobia
atypical anxiety
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PANIC DISORDER
recurrent episodes of intense
apprehension
Fear
terror
accompanied by at least four particular symptoms, all ofwhich reach a peak within 10 minutes.
Attacks are followed by the fear of having additional
episodes
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PANIC DISORDER
key distinguishing feature of panic disorder is theepisodic and recurrent nature of the panic attacks
2 types Panic Disorder with Agoraphobia
Panic Disorder without Agoraphobia
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PANIC DISORDER
onset of panic disorder is generally between theages of 17 and 30 years
It is often precipitated by stressful life events.
familial, with up to 40% of first-degree relatives alsobeing affected
50% to 90% risk of having a major depressiveepisode at some point in their lifetime
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CRITERIAFOR PANIC ATTACK
A period of intense fear or discomfort in which 4symptoms developed abruptly and reached a peakperiod of 10 minutes.
Dyspnea palpitations,
chest pain choking or smothering
Dizziness paresthesias, diaphoresis,
trembling or shaking, chills or hot flashes,
nausea or abdominal distress,
fears of dying, going crazy or losing control during anattack
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CRITERIAFOR PANIC ATTACK
at least one of the attacks must be followed by 1month of persistent concern about having additionalattacks, worry about the implications of the attackor its consequences
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THREE STAGESINTHE DEVELOPMENTOFPANIC DISORDER
Stage 1 : Initial acute panic attack or cluster ofattack Described as the worst experience in their life, after one or a
series of life events overwhelm their coping mechanisms
Stage 2
Panic attacks increase in frequency
phobias develop
anticipatory anxiety and avoidance behavior develop medical care seeking dramatically increases for
somatic complaint
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THREE STAGESINTHE DEVELOPMENTOFPANIC DISORDER
Stage 3: Agoraphobia
fear of the marketplace
Fear of being in places or situation from which escape indifficult , embarrassing in the event of panic attack
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PANIC DISORDER W/O AGORAPHOBIA
The following two conditions are present:
recurrent unexpected panic attacks;
at least one of the attacks has been followed by amonth (or more) of persistent concern about having
additional attacks, worry about the implications of the attacks or their
consequences
a significant change in behavior related to the attacks.
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PANIC DISORDER W/O AGORAPHOBIA
Agoraphobia is not present.
The panic attacks are not a result of the direct
effects of a substance or a general medical
The anxiety is not better accounted for by anothermental disorder
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PANIC DISORDER WITH AGORAPHOBIA
The following two conditions are present:
recurrent unexpected panic attacks;
at least one of the attacks has been followed by amonth (or more) of persistent concern about having
additional attacks, worry about the implications of the attacks or their
consequences
a significant change in behavior related to the attacks.
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PANIC DISORDER WITH AGORAPHOBIA
Agoraphobia is present.
The panic attacks are not a result of the direct
effects of a substance or a general medical
The anxiety is not better accounted for by anothermental disorder
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COMPONENTSOF PANIC DISORDER
Cognitive
Worry
Sense of foreboding
Sense of impending doom or dread
Tendency to be inattentive, distractible
Sense of unreality
Rumination
Loss of control
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COMPONENTSOF PANIC DISORDER
Affective
Isolation
Anxiety or nervousness
Secondary depression
Irritability
Social
Dependency
Vocational limitations
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COMPONENTSOF PANIC DISORDER
Somatic
Tachycardia
Hyperventilation
Diaphoresis
Dizziness or syncope
Flushing
Muscle tension
Tremulousness
Restlessness
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a phobic disorder is the persistent andirrational fear of a specific object, activity, orsituation that results in a compelling desire to
avoid the dreaded object, activity, or situation.
The fear is recognized by the individual asexcessive or unreasonable in proportion to theactual danger of the situation, object, or activity
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Specific Phobia Social Phobia
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A specific phobia involves a persistentirrational fear and compelling desire to avoidan object or a situation.
Common among women
Peak of onset :5-9 yrs for natural environment
type and blood inj type Peak of onset :mid 20s for situational type
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fears are related to most social situations
(e.g., initiating conversations, dating,participating in small groups, attending
parties). has its onset during the teenage years
Onset can occur after a humiliating incident orsituation
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GENERALIZED ANXIETY DISORDER
Generalized anxiety disorder is excessive worry forat least 6 months.
The person finds it difficult to control the worry.
Panic disorder, major depression, alcohol abuse,and organic causes need to be ruled out.
Prevalence is 6% in primary care, affecting twiceas many women as men.
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GENERALIZED ANXIETY DISORDER
The anxiety and worry are associated with at leastthree of the following six symptoms
1. Restlessness or feeling keyed up or on edge
2. Becoming easily fatigued3. Difficulty concentrating or the mind goingblank
4. Irritability
5. Muscle tension6. Sleep disturbance
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GENERALIZED ANXIETY DISORDER
The anxiety, worry, or physical symptoms causeclinically significant distress or impairment in social,occupational, or other important areas offunctioning.
The disorder is not the result of the direct effects ofa substance or a general medical condition
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POST TRAUMATIC STRESS DISORDER
experienced or witnessed a severe catastrophicevent that involved actual or threatened death orserious injury to oneself or others.
They frequently reexperience the event throughdreams or feelings that the event is recurring andmay have panic attacks during these flashbacks.
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CRITERIAFOR POST TRAUMATIC STRESSDISORDER
The person has been exposed to a traumatic eventin which both of the following conditions have beenmet
The person has experienced, witnessed, or been
confronted with an event or events that involve actual orthreatened death or serious injury or a threat to thephysical integrity of oneself or others.
The person's response involved intense fear,helplessness, or horror
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CRITERIAFOR POST TRAUMATIC STRESSDISORDER
The traumatic event is persistently reexperienced inat least one of the following ways
Recurrent recollections of the event, including images,thoughts, or perceptions.
Recurrent distressing dreams of the event.
Acting or feeling as though the traumatic event wererecurring
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The traumatic event is persistently reexperienced in atleast one of the following ways
Intense psychological distress at exposure to internal or
external cues that symbolize or resemble an aspect ofthe traumatic event.
Physiologic reactivity on exposure to internal or externalcues that symbolize or resemble an aspect of thetraumatic event.
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CRITERIAFOR POST TRAUMATIC STRESSDISORDER
Persistent avoidance of stimuli associated with thetrauma and numbing of general responsiveness(not present before the trauma at least 3 of thefollowing
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Efforts to avoid thoughts, feelings, or conversations
associated with the trauma Efforts to avoid activities, places, or people that arouse
recollections of the trauma
Inability to recall an important aspect of the trauma
Markedly diminished interest or participation in significantactivities
Feeling of detachment or estrangement from others
Restricted range of affect
Sense of a foreshortened future
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CRITERIAFOR POST TRAUMATIC STRESSDISORDER
Persistent symptoms of increased arousal (notpresent before the trauma), as indicated by at leasttwo of the following:
Difficulty falling or staying asleep
Irritability or outbursts of anger
Difficulty concentrating
Hypervigilance
Exaggerated startle response
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CRITERIAFOR POST TRAUMATIC STRESSDISORDER
The duration of the disturbance is longer than 1month.
The disturbance causes clinically significantdistress or impairment in social, occupational, or
other important areas of functioning.
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HISTORY The history is probably the single best diagnostic
tool in the workup of an anxious patient, whetherthe anxiety is of an acute or chronic nature.
The history taking process should be sufficientlyopen-ended and unhurried to elicit informationabout the patient's concerns and fears, current life
situation, family and other support systems, andconcurrent medical problems.
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PHYSICAL EXAMINATION
The patient looks worried and acts tense.
Increased motor activity is often evident,
Facial muscles may show twitching or tics.
Breathing is often rapid and superficial and, unsteady voice, strained facies, grinding of teeth,
dilated pupils
tremor of hands, flushing and excessive
perspiration, and labile hypertension.
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MANAGEMENT
Prerequisites for the Physician
Adequate Workup
Treatment Based on Cause
Development of a Therapeutic Plan his plan usually entails a series of office visits on a
regular basis over time and may require specifictherapeutic interventions,
provides the physician opportunity to reassess the
effectiveness and progress of management p
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Education
Building Support Mechanisms
Members of the extended family and friends arefrequently helpful in this respect
It is often useful to involve other family members indevelopment of the therapeutic plan.
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PANIC DISORDER
Pharmacologic therapy, once effective, should befollowed by gradual reexposure to the situationsthat were being avoided.
Start with a selective serotonin reuptake inhibitor(SSRI) or tricyclic antidepressant such asimipramine at a low dosage and then increase untilepisodes cease.
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PANIC DISORDER
first-line treatment of choice for panic disordershould be SSRIs.
paroxetine, sertraline, fluoxetine, citalopram, andfluvoxamine
Started at a low doasge Increased dosage by 5mg until panic attacks
disappear
Common S.E: Jitteriness, nausea headache
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PHOBIC DISORDERS
desensitization,
the patient learns a relaxation technique and then, whilein a relaxed state, is exposed to a gradual hierarchy ofstimuli (through imagery or in vivo) that approaches the
phobic object or situation For agoraphobia, evidence from two studies has
shown that imipramine in combination withexposure enhances the effects of exposure
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POST-TRAUMATIC STRESS DISORDER
SSRIs are effective in civilians but not veterans,whereas imipramine and monoamine oxidaseinhibitors (MAOIs) are effective in veterans.
Cognitive-behavioral therapy and eye movementdesensitization therapy have been shown to beeffective.
The combination of antidepressant medication andpsychotherapy may be optimal therapy.