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Why HK needs a cervical screening program?
How do we bring it about? What is the screening policy? What are the key elements? What are the expected benefits?
Burden of Disease (1999)
Cervical cancer is the fourth commonest cancer in women 436 new cases (4.7% of total cancers) Median age at diagnosis 54 years
Cervical cancer is the seventh leading cause of cancer deaths in women 159 deaths (3.8 % of total cancer deaths)
Trend of Age-standardised Incidence & Mortality Ratesof Cervical Cancer in Hong Kong
2018.7 18.6
16.116.8
15.7 16
14.4 13.9 13.412.7
13.5
11.3 11.2 11.6
9.8
4.6 5 5.1 4.53.8 4 3.9 4.4 3.9 4 3.6 4.1
3.1 3.3 3.2 3.5
23
5.2
2.6
0
5
10
15
20
25
1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000
Year
No.
of n
ew c
ases
and
dea
ths p
er 1
00,0
00 st
anda
rd fe
mal
e po
pula
tion Incidence Rate
Mortality Rate
Sources: Hong Kong Cancer Registry Census and Statistics Department, HKSAR Government
International Comparison
Age-standardized Mortality Rates
0.8
1.2
1.8
1.9
2.3
2.4
2.6
2.6
2.6
2.7
2.9
2.9
4.3
4.3
0.0 1.0 2.0 3.0 4.0 5.0
Italy (1997)
Finland (1998)
The Netherlands (1999)
Australia (1998)
US-White (1995-99)
United Kingdom (1999)
Sweden (1997)
Germany (1999)
Hong Kong (2000)
Ireland (1999)
New Zealand (1998)
European Union (1997)
US-Black (1995-99)
Singapore (1998)
Rates (per 100,000 standard population)
Age-standardized Incidence Rates
3.8
6.5
6.9
7.0
7.4
8.0
8.2
8.5
8.6
9.4
9.8
12.9
14.2
19.1
0.0 5.0 10.0 15.0 20.0 25.0
Finland (1999)
The Netherlands (1997)
Italy (1997)
Australia (1998)
United Kingdom (1998)
Ireland (1997)
European Union (1997)
New Zealand (1998)
Sweden (1997)
Germany (1997)
Hong Kong (1999)
US(SEER)*-Black (1995-99)
Singapore (1993-97)
US(SEER)*-White (1995-99)
Rates (per 100,000 standard population)
Hong Kong (2000)
Hong Kong (1999)
Coverage rate
Women aged 25-49 53% had cervical smear in past 3 years (FPA, 1997)
Women aged 50-64 43% had cervical smear in lifetime (HKU, 1999)
Women aged 65+
18% had cervical smear in lifetime (HKU, 1999)
Countries with organized screening programs: coverage rate 65-85%
Current problems (1)
Opportunistic screening
Variable screening practices
Women not screened according to risk or need
Current problems (2)
Lack of an agreed set of quality management guidelines, indicators, and monitoring mechanism
Lack of central registry for cervical smears
Lack of public-private collaboration
Rationale for screening program Cervical cancer causes significant mortality and
morbidity
Cervical cancer rates are relatively high internationally
Current problems in cervical screening result in low coverage rate
An organized screening program may prevent an estimated 144-183 new cases a year (McGhee, 2002)
Policy initiative
The Policy Address pledged to launch a Cervical Screening Program for women in collaboration with other health services providers in 2003-04
Program goal
To achieve higher and more equitable screening coverage in the target population, thereby reducing incidence and mortality of cervical cancer in Hong Kong
Outline
Why HK needs a cervical screening program?
How do we bring it about? What is the screening policy? What are the key elements? What are the expected benefits?
Cervical Screening Task Force
Professional colleges
Hong Kong College of Family Physicians
Hong Kong College of Obstetrics and Gynecology
Hong Kong College of Pathologists
Cervical Screening Task Force
Professional societies Hong Kong Society for Colposcopy and
Cervical Pathology
Hong Kong Society of Cytology
Cervical Screening Task Force
Service providers
Family Planning Association Hospital Authority Private doctors and laboratories Department of Health
Cervical Screening Task Force
Community and consumer groups
Hong Kong Federation of Women
Hong Kong Cancer Fund
Three Working Groups
Working Group on Recruitment and Education
Working Group on Quality Management
Working Group on Information Systems
Consultative process
Questionnaire surveys to private doctors and laboratories
Field visits to private laboratories and major providers
Women’s focus groups
Outline
Why HK needs a cervical screening program?
How do we bring it about? What is the screening policy? What are the key elements? What are the expected outcomes and
benefits?
Screening Policy Women aged 25-64
Triennial Pap smears after two consecutive yearly negative smears
Women aged 65 and above Two consecutive yearly negative smears, then
discontinue
Women aged below 25 Individual risk profile
Age-specific Incidence Rates for Cervical Cancer, 1983-1999
0
10
20
30
40
50
60
70
80
90
1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999
Year
Rat
e pe
r 10
0,00
0 w
omen
15 - < 25
25 - < 35
35 - < 50
50 - < 65
65+
Age Group
Rationale for starting at 25 Extremely low incidence of cervical cancer below age
25 (only 1 in 436 new cases, 1999)
Regression of cervical dysplasia in younger women
More false positives in women aged<25
In line with international programs (18-30)
Rationale for 3-yearly screen
Very little marginal benefit for more frequently screening 1-yearly screen: 94% reduction 2-yearly screen: 93% reduction 3-yearly screen: 91% reduction
In line with HKCOG recommendation
Target coverage
Interim 60% coverage for women aged 25-64, 3
years after program launch (present estimated coverage: 45%)
Long term
On par with international best practices
Additional smears and colposcopies
If target coverage of 60% is reached, 40% more smears annually (370,000
520,000)
26-45% more colposcopies, to be shared
by public and private sector (estimated by HA)
Outline
Why HK needs a cervical screening program?
How do we bring it about? What is the screening policy? What are the key elements? What are the expected benefits?
Quality Management
Adopt guidelines and standards from local professional organizations
Hong Kong College of Obstetrics and Gynecology:
Guidelines on the management of an abnormal cervical smear
Hong Kong College of Pathologists: Basic Criteria for a Cervical Cytology Screening Laboratory
Quality Management
Adopt guidelines and standards from local professional organizations
Hong Kong Society of Cytology: Cervical
Cytology Practice Guidelines
HKSCCP and HKCOG: Colposcopy Service Provision and Standards
Examples
Both conventional and liquid-based cytology methods are acceptable
Bethesda system recommended
Quality performance indicators, e.g., Report turnaround time Proportion of ASCUS
Training and support for quality Refresher courses in smear taking
e.g., HKCPath/SPACE, CUHK
Training kit for doctors Video, manual, CD-ROM
Training of colposcopists
Requirements being developed by HKSCCP & HKCOG
Supervised on-job training Both clinical and communication skills
Recruitment of women
Prioritized into 3 groups
women aged 50-64 women aged 35-49 women aged 25-34
Specific messages will be developed for each of the 3 groups (e.g., focus group studies)
Rationale for prioritization
Emphasis should go to women who have never been screened women at higher risk of cervical cancer
Better control pace of program
Ensure services not overwhelmed
Methods of recruitment (1)
Personalized invitation letters effective from overseas experience HA Patient Master Index
Women in the 3 prioritized groups will receive invitation letters in a 3-year cycle e.g., first year 50+, second year 35-49,
third year 25-34
Methods of recruitment (2)
Reminder letters for women whose next smear is due
Mass media campaign and publicity materials
Community organizations
Outreach to promote screening
Methods of Recruitment (3)
Provider support, especially private sector Training kits on smear taking Pamphlets for clients Enquiry for smear results Reminder letters Statistical reports Website information
Cervical Screening Information System (CSIS)
Central registry of cervical smear results
Bethesda system for cytology reporting
Cytology-biopsy correlation
Data source
Laboratories performing cytological examination
Major service providers Family Planning Association Hospital Authority Large group practices Department of Health
Minimum data set
Basic items only Patient record
name, HKID, date of birth, etc.
Smear record Smear result, smear taker, date of report, etc.
Follow up record Colposcopy result, histology report, date of report,
etc.
Functions of CSIS (1)
Maintain information on screening history and results
Track utilization and issue reminders
Support quality management and monitoring
Functions of the CSIS (2)
Facilitate record linkage
Program evaluation and research
Ensure data privacy and confidentiality
Data privacy CSIS must comply with Personal Data (Privacy)
Ordinance
Ordinance allows analysis of data in aggregate form
Patient consent may be required for sending individual reminders
Focus groups to find out how women think about privacy of smear results
Outline
Why HK needs a cervical screening program?
How do we bring it about? What is the screening policy? What are the key elements? What are the expected benefits?
What differences the CSP makes (1) Explicit screening policy and target population
Consensus quality management guidelines
and standards
Personalized invitation letters and reminders
Targeted recruitment of women according to risk
What differences the CSP makes (2) Coordinated and sustained education campaigns
Greatly improved provider support and training
Evaluation of program via performance indicators
Cervical Screening Information System
Collaboration and consensus building among various
sectors, including public and private sector
Benefits to the community
Improved overall coverage of the target population not achievable by opportunistic screening
More equitable cervical screening service particularly for women at high risk / not screened before
Better quality assurance in cervical screening service provision