Bodybuilding Nutrition5

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  • 120 Bodybuilding Supplement Guide

  • Commiphora mukulis an herb knownas guggul. Just as that plant hasunique and interesting names, so italso has unique and interesting effectson the human body. Guggul is a tree that grows in India that exudes a

    resinous sap from its bark. The resin has been usedfor centuries in Indias traditional Ayurvedamedicine. In our modern world of advanced chem-istry the sap is processed and purified and thenstandardized for its active constituentsZ and Eguggulsterones. The two compounds are plantsterols that have a high degree of human bioactivityand have been shown in studies to affect many bio-logical processes, including thyroid metabolism,cholesterol management and dermal, or skin, func-tion. In each of those areas guggulsterones wereshown to be highly effective modulators with near-druglike potency.

    Bodybuilders are concerned with not only build-ing solid muscle tissue but also reducing theamount of fat deposits. You may weigh 240 poundsand have a tremendous amount of muscular devel-opment, but if you have two inches of subcuta-neous fat all over your body, you wont look all thatgreat. You definitely wont be aesthetically pleas-ing, and some people might even call you dough-boy. A thyroid-stimulating substance might beexactly what you need.

    I first became interested in guggulsterones whenI noticed studies on their thyroid-stimulating prop-erties. I discovered that guggulsterones have a di-rect stimulating action on the thyroid gland throughenzymatic mechanisms. One study concluded thattheyre a viable option for the treatment of hy-pothyroidal conditions. The warm feeling, thesweating and the rise in body temperature confirmguggulsterones thyroid-stimulating ability. Thatsgood news for those of us who are trying to loseweightespecially adipose tissue, or fat stores.When the thyroid gland is stimulated, it producesmore thyroid hormones, such as thyroxin, which

    have a profound effect on the rate of metabolism,including a direct catabolic effect on adipose tis-sue. That means guggulsterones will stimulateyour thyroid to produce more thyroid hormones,which in turn will raise your metabolic rate andburn more fat.

    Guggulsterones by themselves have been shownto work very well for fat loss, but Ive found acombination thats nothing short of amazingguggulsterones and an ECA stack such asAdipokinetix. We already know that Adipokinetixis an extremely potent fat burner, but it does itswork outside the realm of the thyroid. It madesense to me that if one could combine the fat-burn-ing effects of the thyroid hormones with those ofthe adrenergic hormones (e.g., adrenaline), some-thing very dramatic would result. Also, ECAstacks tend to decrease the amount of thyroid hor-mones circulating in the blood over time. Guggul-sterones do a great job of inhibiting that reduction,thus keeping all physiological fat-burning systemsoperating at a maximum level.

    The final ways in which guggulsterones can ben-efit in the fight to burn fat involve ketogenic dietsand growth hormone use. Over time ketogenicdiets tend to reduce the thyroids effectiveness byreducing the conversion of T4 to the more potentT3. Guggulsterones wont do anything to increasethe conversion, but they will cause more T4 re-lease, which in turn should increase T3 to some ex-tent. Furthermore, although T4 is not as potent ametabolic regulator, it is functional and should in-herently help boost the metabolic rate. RegardingGH use, anyone who has taken this potent hor-mone knows that it vastly reduces the amount ofthyroid hormones that are produced by the thyroidgland. Again, although Ive never tried it and dontknow of anyone who has, guggulsterones shouldhelp lessen the thyroid-hormone-reducing effect.

    Although their fat-burning properties are whatwere most interested in, guggulsterones also havean extremely beneficial effect on cholesterol and

    Bodybuilding Supplement Guide 123

    Guggulsterones: Turn Up the Heat toBurn More Fat

    by Derek Cornelius

    122 Bodybuilding Supplement Guide

  • Bodybuilding Supplement Guide 125124 Bodybuilding Supplement Guide

    triglyceride levels. Numerous clinical studies have shown that theycause a 14 to 27 percent decrease in total cholesterol in a four-to-12-week period, while triglyceride levels drop 22 to 30 percent. Even moreinteresting is the fact that guggulsterones support a high high-densitylipoprotein (HDL), or good cholesterol, level and a low low-densitylipoprotein (LDL), or bad cholesterol, level. Study after study con-firms that guggulsterones are as potent as many of the current prescrip-tion drugs for lowering LDL cholesterol. Unlike their drugcounterparts, though, guggulsterones have absolutely no negative sideeffects.

    The cholesterol-reducing effect is important for anyone whos inter-ested in keeping a healthy cardiovascular systemespecially thosewho use steroidal compounds. Anabolic/androgenic steroids increasenot only total cholesterol but also the ratio of LDL to HDL.

    Its hard to imagine a compound that beneficial having any more ben-efits, but guggulsterones have also been proven as effective as the drugtetracycline in treating acne. In a 1994 study published in the Journal ofDermatology, 20 patients with nodulocystic acne were randomly giveneither tetracycline or guggulsterones. Both were taken daily for threemonths, and both produced a progressive reduction in the lesions in themajority of the patients. Tetracycline reduced them by 65.2 percent,while the guggulsterones produced a 68 percent reduction.

    Who can benefit from gugguls effects? Well, who wouldnt like abetter complexion? Thats especially true for people on anabolic/andro-genic steroids, as those drugs tend to increase the skins oiliness and po-tential for acne.

    Where else can you find a compound that will help you lose fat, im-prove your cholesterol profile and at the same time improve your com-

    plexion? Ivelooked long andhard and have yetto find even onecompetitor. Youshould take 30 to60 milligrams threetimes per day withmeals, and alwaysuse a product thatcontains the high-potency, naturallyextracted guggul.

    Editors note:Derek Cornelius isa respected bio-chemist and theowner of SyntraxInnovations Inc.

    Guggulsteroneshave a direct

    stimulatingaction on thethyroid gland


    mechanisms.One study

    concluded thattheyre a viable

    option for thetreatment of


    Adipokinetix is a supplement that mobilizes and burns

    fat tissue without sacrificing muscle and organ tissue. You

    should be familiar with the ECA stacka combination of

    ephedrine, caffeine and aspirin. Adipokinetix is similar to

    ECA but is a vast improvement. It takes fat mobilization

    and burning to a new level. Adipokinetix contains precise

    ratios of 1R,2S norephedrine HCl, caffeine, yohimbine HCl

    and now 50 milligrams of theophylline. The aspirin is left

    out because some people are sensitive to

    it. Furthermore, aspirin is cheap, easy to

    get and can be easily added to the stack

    if you can tolerate it.

    The first two compounds1R,2S

    norephedrine and caffeinework to-

    gether in much the same way ephedrine

    and caffeine work. The difference is that

    studies have shown norephedrine to be

    the most potent and most thermogenic

    of the ephedrine alkaloids.

    Norephedrine also lacks some of the

    central-nervous-system-stimulating ef-

    fects of ephedrine. In practical terms

    that means an individual will still feel a

    little wired but not nearly as much as he

    or she will feel with ephedrine. Another

    plus for norephedrine is that it doesnt

    have the negative associations that

    ephedrine hasthere are no Food and Drug Administr a-

    tion restrictions and no negative publicity. In the coming

    years norephedrine will definitely be the compound of

    choice for easy, effective weight lossinstead of the ECA

    stack, youll hear about the NCA stack.

    Norephedrine and caffeine work synergistically to drasti-

    cally increase the bodys production of adrenaline and no-

    radrenalinethe adrenergic hormoneswhich bind to the

    adrenergic receptors. There are a number of different

    adrenergic receptors: the alpha sub 1, alpha sub 2, beta sub

    1, beta sub 2 and beta sub 3. We are mainly interested in the

    alpha-sub-2, beta-sub-2 and beta-sub-3 receptorsfor

    theyre the ones that mainly affect fat loss and mobiliza-


    Among other things, the beta-sub-2 and beta-sub-3 re-

    ceptors are responsible for the mobilization and burning of

    adipose tissue; so they are the receptors that you want to

    stimulate, for they ultimately affect fat loss in a positive

    way. Another positive benefit of stimulating the beta-sub-2

    receptors is an anticatabolic effect on proteinaceous tis-

    sues. Thus, you simultaneously lose fat without sacrificing

    much or any muscle tissue.

    The other receptor that were interested in is the alpha-

    sub-2 receptor. Studies have shown that it blocks the mobi-

    lization of adipose tissue. In terms of fat loss its the bad

    guy. In fact, its the receptor that causes

    women to have a harder time losing adi-

    pose tissueespecially in their lower bod-

    ies. Women have many more alpha-sub-2

    receptors than men, and they have an

    even greater number in their lower bodies.

    To combat those nasty receptors, we need

    a compound thats naturally occurring,

    easy to get, potent, lacking negative side

    effects and able to block them. Yohimbine

    is the answer.

    Yohimbine does all of the above with an

    added bonusits a proven aphrodisiac.

    Thus, with Adipokinet