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BISC800Basic skills
for a career in scienceFall 2010
Julian [email protected]
Course website:www.sfu.ca/biology/faculty/christians/bisc800
Who am I?
Who are you?
Course scheduleDate Topic
September 27 Course introductionGrant, scholarship and fellowship applications, CVs
October 4 Giving good talks
Long break!November 1 Being a scientist + student presentations
November 8 Writing Abstracts and Introductions + student presentations
November 15 Writing Methods, Results and Discussions
November 22 Preparing posters + Publishing and reviewing papers
AssessmentAssignment Due on
Write NSERC Contributions and Statement
Wednesday, October 27
Ten minute presentation with powerpoint
Presented in class November 1 and November 8
Write an abstract of a paper provided in class
Monday, November 15
Write an introduction to an NSERC Discovery Grant proposal
Monday, November 22
Review two proposals from peers
Monday, December 6
Scientific writing
• Thesis• Grant/fellowship applications• Papers• Letters (job applications)• CVs• Popular articles • Abstracts (conferences)• Emails
General structure
Introduction
Methods
Results
Discussion
Theses, grant applications, papers, abstracts
All background knowledge + question(s)
Step-by-step description of work
What are results are, without interpretation of meaning
Consideration of results in relation to question posed
1. Avoid focus 2. Avoid originality and personality 3. Write long contributions 4. Remove implications and speculations 5. Leave out illustrations 6. Omit necessary steps of reasoning 7. Use many abbreviations and terms 8. Suppress humor and flowery language 9. Degrade biology to statistics 10. Quote numerous papers for trivial statements
How to bore your readers
Sand-Jensen 2007 Oikos
1. Avoid focus
2. Avoid originality and personality
The solutions
Spell out your question/hypothesis
The experiment was conductedor
We conducted the experiment
Use the active voice as much as possible
3. Write long contributions
4. Remove implications and speculations
The solutions
Shorter is always better
The height of men was great than the height of womenor
Men were taller than women
Relate your results to an important problem, but be modest with speculation.
7. Use many abbreviations and terms
The solutions
Just don’t do it !
The BCL-2-like protein CED-9 of C. elegans promotes FZO-1/Mfn1,2-and EAT-3/Opa1-dependent mitochondrial fusion
CED-9 promotes mitochondrial fusion in C. elegans.
9. Degrade biology to statistics
10. Quote numerous papers for trivial statements
The solutions
Always ask yourself: ‘Would the reader know what I’m working on?’
The correlation was significantly positive between the two variables tested.or
Male interest increased with female attractiveness.
Unless Darwin said it, it can be rephrased!
Getting grants and scholarships
Upcoming deadlines
• NSERC – October 6 (to department)
• CIHR – doctoral – October 15 (at CIHR)
• CIHR – master’s – February 1 (at CIHR)
Grants and scholarships
• What’s the difference?
• Where to find them
• Why applications are rejected
• How to write a good application• The project• You
What’s the difference?
ScholarshipsGrants
• Research support
• Project description most important
• Committee looking for reason NOT to fund you
• Student support
• Student track record most important
• Committee looking for reasons to fund you
Novelty & feasibility Achievements
Finding sources of money
• International• Federal• Provincial • University GFs & Private
ScholarshipsGrants
http://www.biology.sfu.ca/degree/graduate/financialhttp://www.sfu.ca/dean-gradstudies/scholarships_and_awards/
• Research councils• Government agencies• Corporations• Foundations & charities• NGOs
WebSupervisorOther studentsScientific societies
Two scholarship sources to note
• Awards made on basis of academic merit• minimum criterion for eligibility CGPA ≥ 3.5• one-semester awards• $6,250 • application deadline : 15 April
http://www.sfu.ca/dean-gradstudies/scholarships_and_awards/graduate_fellowships/
Graduate fellowships
Two scholarship sources to note
http://www.sfu.ca/dean-gradstudies/scholarships_and_awards/internal_awards/
• Often department or field-specific• Various eligibility criteria• Various deadlines: Jan, March, April, May, Sept
Private awards
Private awards – Sep 30 deadline!Graduate Award
Eligible Graduate Program(s) (see Terms of Reference)
Number of Awards Available
Value per Award
Glen Geen Graduate Scholarship in Marine Biology
Biological Sciences 1 $790
H.R. MacCarthy Graduate Bursary Biological Sciences 1 or 2 $3,800 or
$7,600
J. Abbott / M. Fretwell Graduate Fellowship in Fisheries Biology
Biological Sciences 1 $4,000
Mutual Fire Insurance Company of BC Graduate Scholarship in Biological Sciences
Biological Sciences 1 $4,600
Phyllis Carter Burr Graduate Scholarship in Developmental Biology and Cell Biology
Biological Sciences, Molecular Biology & Biochemistry, Biomedical Physiology & Kinesiology
2 $2,350
Sidney Hogg Memorial Graduate Scholarship Various programs in Faculty of Science 1 $700
Sulzer Pumps Inc. Graduate ScholarshipVarious programs in Faculty of Science or Faculty of Applied Science
2 $1,000
Once you’ve found a source
• Current guidelines• That the granting body funds the kind of project you have in mind or people like you• Eligibility criteria – that you fit ALL of them• The deadline!
Check:
Remember!
• Awarded (usually) on the basis of merit, not need!
• Rejection rates can be very high
(50-80+%)
Why are applications rejected?
You dropped the ball
• Deadline not met
• Guidelines not followed
Why are applications rejected?
Weak project
• Project predictable, routine or repetition
• Unrealistic budget/ timeframe/ workload
• Necessary resources not available
• Applicant/ team not suitable
Why are applications rejected?
Good project, but weak presentation• Objective unclear• Proposed methods unclear• Not enough detail in budget• Potential obstacles not discussed• Insufficient literature review• Insufficient knowledge of field• Poor writing: long, repetitious, ambiguous• Biased position
Why are applications rejected?Biased positionGrant submitted to SSHRC: Detrimental effects of popularizing anti-evolution's
"intelligent design theory" on Canadian students, teachers, parents, administrators and policymakers.
Committee’s response:The committee found that the candidates were qualified.
However, it judged the proposal did not adequately substantiate the premise that the popularization of Intelligent Design Theory had detrimental effects on Canadian students,teachers, parents and policy makers. Nor did the committee consider that there was adequate justification for the assumption in the proposal that the theory of Evolution, and not Intelligent Design theory, was correct.
http://leiterreports.typepad.com/blog/2006/04/canadian_sshrc_.html
Who are the reviewers?
• Unlikely to be experts in your exact subject area – but will usually be scientists
• Assume they are uninformed, but infinitely intelligent
• Often 2-3 reviewers per proposal
• Often 100 proposals per reviewer!
?
Writing the application: about the work
• Read the instructions!• If outline of sections is provided, follow it.• If not, you should have:
– Title– Summary (10%)– Justification (background) (20%)– Aims (10%)– Methods (30%)– Outputs (15%)– Budget (10%)– Time schedule (5%)
Title
• The reviewer’s first impression• Clever, catchy, clear and informative but not cute• If it’s a question, make sure your data will answer it• Avoid acronyms, scientific names, and jargon• Use words/expressions found in the mission of
your target funding body
Examples
A study of the correlates of the distribution of
Microspathodon chrysurus
What determines the distribution of the endangered
yellowtail damselfish?
BAD GOOD
Biodiversity of amphibians in Tanzania
Does the umbrella species concept work? A test with
Tanzanian amphibians
Do divers break coral when looking at seahorses?
Charismatic fish and diving tourism: impacts on corals
Examples – successful CIHR Master’s awards
• Colour Perception in Children with Autism • Characterizing the Roles of Cytochrome P450 Isozymes in
Breast Cancer • The neural correlates of marijuana addiction: Differences in
drug and emotional stimulus processing in addicted versus healthy controls.
• The Structural and Biochemical Analysis of the BAM complex in Escherichia coli
Summary (abstract)
• The reviewer’s second impression
(and sometimes the only thing s/he’ll read!)
• It should answer 4 questions:– Why is the work important?
– What has already been done?
– What do you intend to do?
– How are you going to do the work?
• Write it last
Justification (background)
• Start with the general area and narrow it down to focus on specific project
• Include brief literature review (key references)• Explain the problem (including lack, knowledge
gaps)• Give reasons for undertaking this particular
research• Indicate why you are well placed to undertake
the project
Justification (background)
• Pitch it to make it fit the mission (within reason!)
• Remember who the reviewers are
• Clear, logical, explicit
• Avoid overkill and hyperbole
Some no-no words
• Critical
• Dramatic
• Tragic
• Hopeless
• Desperate
Readers don’t want to be told how to feel!
Aims/ objectives• One sentence for overall objective• Then provide 2-4 specific objectives
(which are achievable!)• Know the difference between
– Aims– Objectives/ goals– Predictions– Hypotheses– Theories
Example
AIM: The aim of this project is to assess the damage to corals caused by divers seeking fish such as seahorses and frogfish (S/F).
OBJECTIVES: More specifically, I will: (1) compare coral damage at S/F and control sites; (2) record diver behaviour at S/F and control sites; (3) quantify the spatial extent of coral damage; and (4) evaluate the rate of recovery of S/F sites.
ExampleLong-term goal of project: To study the genetic basis of variation in
virulence in A. fumigatus and A. nidulans to identify previously-unknown genes, or to identify new roles for known genes.
Specific objectives:
1. Develop molecular markers spanning the A. fumigatus genome at sufficient density to allow linkage and QTL mapping.
2. Construct a linkage map for A. fumigatus based on these molecular markers by genotyping a panel of progeny from a cross between two strains.
3. Map quantitative trait loci (QTL) that affect virulence (i.e., identify genetic regions containing virulence genes) using the markers and linkage map developed from Objectives 1 and 2.
Methods
• How, when and why
• Describe all activities to be undertaken, the methods for each and when the work will be done
• Link clearly method to objective
• Indicate how data will be analysed
• Justify unorthodox methods
What not to forget
• Details (e.g. no. of transects, transect length, no. of individuals to be observed, for how long, source of reagents, organisms if not standard, etc.)
• Field/lab assistants, local help and contacts
• Relate to your relevant experience• Any ethical issues your work entails• A CONTINGENCY PLAN!
Outputs
• Also called ‘Significance’
• What about negative results?
• What will come out of this project in terms of:– Advancement of science– General benefit to people or species– Data dissemination
Budget
• Be realistic
• Stay within the range usually granted by your target funding body
• Provide a clear breakdown of items and costs
• Justify everything
• Build in some ‘fat’
• Mention other sources of funding
Time schedule
• Can be just a line or two in the methods or
• A small table showing when specific tasks will be carried out
May-June 09 Habitat assessment on dived and control sites
July 09 Observations of diver behaviour
Aug-Sept 09 Data analysis and write-up
Style tips
• Clear and simple• Short sentences, short paragraphs• Font no smaller than 11pt (Times)• Leave spaces (e.g. paragraph indents)• Avoid right justification• No jargon• Avoid ‘this’, ‘that’, and dangling participles
– E.g., Stopping every 5 m to record tree density, 20 transects will be run in total.
More tips
• Avoid spelling mistakes
• Use point form
• Use subheadings, bold or italics (sparingly)
More tips
• Give yourself time
• Read and re-read it (and get your friends to read it too)
• Good proposals are hypothesis-driven
Writing the application: about you
• Highlight your accomplishments in a clear and unambiguous manner
• Sell yourself but don’t exaggerate your contributions
• Where possible, provide objective criteria, e.g., journal impact factors
• Check the criteria to know what to emphasize
Accomplishments
•Published papers in peer-reviewed journals• Productivity and journal rank count• Sole authored papers are valuable• In multi-authored papers, state the role that you
played
•Papers in review• Show that you can complete projects
•Invited talks
Accomplishments
• Unsolicited talks/posters• Demonstrate ability to complete projects
• Technical reports
• Grades
• Awards
Extracurricular stuff
• Mentoring junior students (e.g., undergrads, newbie grad students)
• Teaching •Lecturing•TAing
• Academic admin •Student representative on a Department or University committee
• Career-related volunteer work
What about non-academic stuff?
Getting letters of reference
• Ask for them early
• Provide information• Terms of reference of grant/scholarship• Your proposal• Your CV
• Make sure they know you well
How could you sell your project?
NSERC
The application
• Form 200
• Proposal (=1 page)
• Contributions and statement• MSc: 1 page• PhD: 2 pages• PDF: 4 pages
The process
• Applications assessed by 2 reviewers
• Grade assigned from 10 – 99%
• 50% of PDFs eliminated
• Applications presented by reviewers
• All members grade
• ~5 min per application
• Toxicological risk of nanomaterials in freshwater• Parasites and metallothionine production in fish• Population connectivity in large ungulates• Stability in food webs• Bioamplification of POPs• Polyandry in field crickets• Landscape genetics of wild cats
Subjects Isabelle was asked to review
The criteria: evidenceAcademic excellence
Research aptitude and potential
• Grades (last 2 years), Honour rolls & Dean’s lists• Academic awards
• Proposal and papers• Research awards (e.g. USRAs)• Letters of reference
Communication, interpersonal & leadership abilities• Conferences (esp. awards)• Involvement• Letters of reference
The criteria: weighting
AE
RAP
CILA
MSc PhD PDF
50% 30%
50%
20%
70%
30%
30%
20%
The likelihood of success(if you made it to competition week in 2009)
MSc
PhD
~70%
~60%
~20%
General things that increase your chances
• Follow instructions (esp. about max length)
• Choose your referees carefully
• Get your application read by someone else
• Make things obvious/easy to find
• Write down ALL of your accomplishments
• Emphasise extracurricular activities
Specific things that increase your chances
1. Proposal
• Write a proposal, not a general area of interest• Needs to have:
• Hypotheses/predictions• Details of methods• Significance
• PDFs: (Slightly) new direction is better than same
as PhD• No jargon
Specific things that increase your chances
1. Proposal
• Justification of location of tenure (esp. PDF)• Good justification should have:
• Person• Facilities and support• Opportunities for research collaborations• Other opportunities
Specific things that increase your chances
2. Research aptitude and potential
• Papers, papers, papers (but not just
quantity)• Average # papers in 2008 applications
• PhD applicants: 2.2 (range: 0-10)• PDF applicants: 5.0 (range: 0-24)
• Give impact factor of journals (esp. if high)
Specific things that increase your chances
2. Research aptitude and potential
• Awards: apply for everything you can!• Report $ obtained• NSERC USRAs
Specific things that increase your chances
• Don’t underestimate• Present with clear headings• What to do:
• Conferences• Oral presentations• Teaching experience (TA, outreach)• Involvement in academic and wider community• Organise events/people• Extracurricular breadth
3. Communication, interpersonal & leadership abilities
Specific things that increase your chances
• Make sure the referee knows you• Make sure the referee can say positive things about you• Important to mention:
• Rankings • Info pertinent to project• Info pertinent to RAP and CILA (with evidence)
Letters of reference