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CT and MR Imaging Diagnosis aof Hepatocellular Carcino
Development, Growth, and Spr
"athologic and Imaging #s
D$I: %&'%%()*radiol'%(%++-%
Radiological Societ! of .orth #merica
http:**pu/s'rsna'org*doi*a/s*%&'%%()*radiol'%(%
RI0# 123RI#.4
%%-%&5&((
"em/im/ing
dr' 6!dia "ur/a, Sp'Rad
http://pubs.rsna.org/doi/abs/10.1148/radiol.14132361http://pubs.rsna.org/doi/abs/10.1148/radiol.14132361http://pubs.rsna.org/doi/abs/10.1148/radiol.14132361http://pubs.rsna.org/doi/abs/10.1148/radiol.14132361
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De7nisi dan Insidensi HepatoceCarcinoma
Hepatocellular carcinomatumor epitel !ang terdapat padterdiri
dari sel8sel !ang mirip dengan sel hepar 9hepatosit
"aren;im hepar diganti;an oleh
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1a;tor Resi;o HepatocellularCarcinoma
Sirosis hepatis)&> ;asus HCC dengan sirosis hepatis
Hepatitis 3 dan C
Geogra7
=enis ;elaminla;i8la;i ? perempuan
onsumsi al;ohol ??
Mero;o;
$/esitas
Dia/etes
Hereditar! hemochromatosis
#@atoAin
Riwa!at ;eluarga dengan HCC
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"atogenesis HepatocellularCarcinoma 9Hepatocarcinogene
Hepatokarsinogenesister
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Manifestasi linis HepatocellulaCarcinoma
#simtomati;/ervariasi se ;asus
Ge
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HCC non sirosis:
Malaise
#nore;sia
.!eri perut ;uadran ;anan atasB ;onstan, sering;ali sangat
hemem/uru; setelah ma;an
Distensi a/domen hepatomegali dengan atau tanpa asites
I;terus
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Diagnosis Hepatocel
Carcinoma
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"emeri;saan 6a/oratorium
"emeri;saan penanda tumor#1" 9#lpha 1eto "rotein
Gli;oprotein dihasil;an oleh hepar
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"emeri;saan Imaging
Eltrasonograph! 9ESG
Computed Tomograph! 9CT
Magnetic Resonance Imaging 9MRI
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ESG 9Eltrasonograph!
Diguna;an untu; mengamatiHCC pada C6D
Ting;at sensitivitas dete;si HCC++> 8 F->
.amun, /ila di/anding;andengan CT dan MRI, ting;at
sensitivitas le/ih rendah HCC hipoe;oi; di/anding;an
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Computed Tomograph! 9CT
CT dan MRI dengan ;ontraslini I diagnosis HCC
Dosis: %'5 B m6*g33
9per;iraan: +5&mg iodin*ml
#dministrasi ;ontras: (8-m6*deti;
+ fase:
6ate hepatic arterial
"ortal venous
Dela!ed phase
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Magnetic Resonance Imaging 9
ontras: Gadolinium
GadoAetate disodium
Gado/enate dimeglumine
Dosis ;ontras: &,&58&'%mmol*g33
#dministrasi ;ontras: m6*deti;
+ fase:
6ete hepatic arterial
"ortal venous
Dela!ed phase
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.odul Sirosis
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.odul Displasti;
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Stadium HCC
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Stadium &
St di #
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Stadium #
St di 3
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Stadium 3
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Stadium C
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Stadium C
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Diagnosis 3anding
Cholangiocarcinomas 9CCC
;eganasan pada sistem saluran /iliaris !ang mung;in /erasal
saluran empedu e;strahepati;, !ang /era;hir pada ampula a
Sirosis hepatis
Hepatocellular adenomas 9H#s
Merupa;an tumor
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Daftar "usta;a
%' Choi =in84oung, 6ee =eong8Min, Sirlin' Claude 3' CT and MR
Imaging Diagnosis and StagiHepatocellular Carcinoma: "art I'
Development, Growth, and Spread: e! "athologic anRadiolog! RS.#
&%( : -+58-5&
' Mc2vo!' Sinead H, McCarth!' Colin =, 6avelle' 6isa ", Moran'
Deirdre 2, Cantwell' Colin "=, Gi/ne!' Ro/ert G, Malon' Dermot 2'
Hepatocellular Carcinoma: Illustrated Guide to S!Radiologic
Diagnosis and Staging #ccording to Guidelines of the #merican
#ssociation 6iver Diseases' Radio Graphics &%+ ++:%-5+8%--)
+' Tiwari8Hina #rif, al/ 3o//! , Chundru Sur!a, Sharma "uneet ,
Costello =ames , GuessnMartin' Diego R' MRI of hepatocellular
carcinoma: an update of current practices' Diag&%(
&:&F8%
(' 3ruiA =ordi, Sherman Morris' Management of Hepatocellular
Carcinoma: #n Epdate' ##%&&8%&%
5' 3ruiA =ordi, Sherman Morris' Management of Hepatocellular
Carcinoma: #n Epdate' ##5
-' arsinoma Hepatoseluler' Dia;ses dari
http:**eprints'undip'ac'id*((5*+*/a/J'pdfpaSeptem/er &%5 pu;ul
&'&& I3
' Sari "aramita' 3iomar;ers for Hepatocellular Carcinoma'
Dia;ses dari
http:**www'scri/d'com*doc*%-(&))+*3iomar;ers8for8Hepatocellular8CarcinomaKscri/d
padSeptem/er &%5 pu;ul +'&& I3
http://eprints.undip.ac.id/44757/3/bab_2.pdfhttp://eprints.undip.ac.id/44757/3/bab_2.pdfhttp://www.scribd.com/doc/164208823/Biomarkers-for-Hepatocellular-Carcinoma#scribdhttp://www.scribd.com/doc/164208823/Biomarkers-for-Hepatocellular-Carcinoma#scribdhttp://www.scribd.com/doc/164208823/Biomarkers-for-Hepatocellular-Carcinoma#scribdhttp://www.scribd.com/doc/164208823/Biomarkers-for-Hepatocellular-Carcinoma#scribdhttp://eprints.undip.ac.id/44757/3/bab_2.pdfhttp://eprints.undip.ac.id/44757/3/bab_2.pdfhttp://eprints.undip.ac.id/44757/3/bab_2.pdf
