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Table S2. Extracted data from experimental studies Reference Sample Characterist ics Study Design Randomisat ion Methodolog y & Details of Blinding Details of Training (duration, sessions, task stimuli) Underlyin g Automatic and/or Regulator y Processes Primary Outcomes (related to food or automatic/ regulatory processes) Additional Outcomes Reported (i.e. engagement, attrition, adverse effects) Key Findings Quality Assessment Boutelle et al., 2014 *Effect sizes calculated for d 29 children 8-12 years Mean age: 10.83 (1.28) BMI = 26.04kg/m 2 (4.08) F: 46%; M: 54% Training condition 14 children Mean age: 10.40 (1.24) BMI = 25.70kg/m 2 (3.78) F: 53.3%; M: 46.7% Control condition 15 children Randomised controlled trial Not specified Type of training: Attention bias modificati on 1-session; 288 trials Training condition: Attention trained away from unhealthy food words toward neutral words 100% of the time Control Attention bias Pre-and-post training Eating in absence of hunger (EAH) paradigm Unhealthy snack consumption in the absence of hunger Calculated calories consumed (EAH kcal) and percent of daily calorie needs consumed (EAH percent) Modified dot probe paradigm Attention bias No significant group by time interaction for attention bias, p = 0.073; No significant difference in attention bias in the training condition (p = 0.546, d = 0.26), or in the control condition p = 0.073, d = 0.63 from pre-to-post training. Significant group by time interaction for EAH percent, p = 0.018; 52%; Fair

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Page 1: ars.els-cdn.com  · Web viewDetails of Training (duration, sessions, task stimuli) Underlying Automatic and/or Regulatory Processes. Primary Outcomes (related to food or automatic

Table S2. Extracted data from experimental studies

Reference Sample Characteristics

Study Design Randomisation Methodology & Details of Blinding

Details of Training (duration, sessions, task stimuli)

Underlying Automatic and/or Regulatory Processes

Primary Outcomes (related to food or automatic/ regulatory processes)

Additional Outcomes Reported (i.e. engagement, attrition, adverse effects)

Key Findings Quality Assessment

Boutelle et al., 2014

*Effect sizes calculated for d

29 children8-12 yearsMean age: 10.83 (1.28)BMI = 26.04kg/m2

(4.08)F: 46%; M: 54%

Training condition14 childrenMean age: 10.40 (1.24)BMI = 25.70kg/m2

(3.78)F: 53.3%; M: 46.7%

Control condition15 childrenMean age: 11.29 (1.20)BMI = 26.40kg/m2

(4.48)F: 35.7%; M: 64.3

Randomised controlled trial

Not specified Type of training: Attention bias modification

1-session; 288 trials

Training condition:Attention trained away from unhealthy food words toward neutral words 100% of the time

Control condition:Attention trained toward unhealthy food words 50% of the time and neutral words 50% of the time

Attention bias Pre-and-post training

Eating in absence of hunger (EAH) paradigmUnhealthy snack consumption in the absence of hungerCalculated calories consumed (EAH kcal) and percent of daily calorie needs consumed (EAH percent)

Modified dot probe paradigm (stimuli not trained)Attention bias

Attention bias

No significant group by time interaction for attention bias, p = 0.073;No significant difference in attention bias in the training condition (p = 0.546, d = 0.26), or in the control condition p = 0.073, d = 0.63 from pre-to-post training.

Significant group by time interaction for EAH percent, p = 0.018;No significant change in EAH percent in the training condition from baseline to post-training (p = 0.466, d = 0.12).Control condition significantly increased EAH percent from baseline (M = 9.6, SD = 3.6); to post-training (M = 12.2, SD = 2.4), p = 0.006, d = 0.85.

Significant group by time interaction for EAH kcal, p = .022.No significant change in EAH kcal in the training condition from baseline to post-training (p = 0.542, d = 0.12).Significant increase in EAH

52%; Fair

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kcal in the control condition from baseline (M = 246.9, SD = 104.1) to post-training (M = 312, SD = 79.3), p = 0.009, d = 0.70.

Baseline attention bias did not moderate the between group change in EAH percent (β = 2.18, t = 1.46, p = 0.159) or EAH kcal (β = 2.49, t = 1.71, p = 0.103).

(Folkvord, Veling et al. 2016)

133 children7-10 yearsObese (3.8%); overweight (18.9%); normal-weight (73.5%); underweight (3.8%)F: 47%; M: 53%

Randomised controlled trial

Not specified Type of trainingModification of implicit processes in relation to eating behaviour

1-session; 132 trials

Go/no-go task

Go/no-go food task; 22 images of cute animals (go trials); 22 different images of jelly candy (no-go trials)

Go/no-go control task; 22 images of cute animals (go trials); 22 control images (coloured circles) (no-go trials)

Implicit biases Post-training

Food intake; jelly candy (trained stimuli); milk chocolate candy shells (stimuli not trained)Ad libitum food intake of unhealthy foods

Food intake

Significant between-group difference in total food intake, F(1, 129) = 6.32, p = 0.01, d = 0.44;Children in the go/no-go food task consumed significantly less (M = 169.6 kcal, SD = 117.0 kcal) than those in the go/no-go control task (M = 226.0 kcal, SD = 142.2 kcal).

50%; Fair

(Jiang, He et al. 2016)

40 children

Training condition20 childrenMean age: 6.30 years (0.47)

Randomised controlled trial

Randomised according to student number

Blinding not specified

Type of trainingInhibitory response modification

Training

Generic inhibitory control

Pre-and-post training

Generic go/no-go task paradigm (stimuli not trained)Generic inhibitory

Generic inhibitory control

Significant correlation between BMI and commission errors in the pre-training go/no-go task (r

50%; Fair

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BMI range = 12.56- 19.66BMI = 15.97kg/m2

(1.68)F:10; M: 10

Control condition20 childrenMean age: 6.40 years (0.50)BMI range 13.92-19.68BMI = 16.05kg/m2

(1.64)F:10; M: 10

condition

6 consecutive days of training; 10 minutes per day; 5 blocks of 40 trials

3 within-subjects conditions1. Inhibition

manipulation; food paired with no-go signal

2. Impulsivity manipulation; food paired with a go signal

3. Control manipulation;50% of time food paired with go signal, 50% of time food paired with no-go signal

Control Condition6 consecutive days; 10 minutes per day

Played with Lego blocks

control

Taste test; foods used during trainingFood consumption

= 0.70, p < 0.001).

Training condition: commission errors significantly reduced from pre-training (M = 9.13, SD = 4.54) to post-training (5.93, SD = 4.85),t(19) = 3.17, p = 0.005, r2 = 0.35, errors of omission significantly reduced from pre-training (M = 9.38, SD = 5.13) to post-training (M = 5.13, SD = 6.86), t(19) = 3.70, p = 0.002, r2 = 0.42,go response time was significantly faster post-training (M = 561.25, SD = 125.03) than pre-training (M = 631, SD = 123.07), t(19) = 3.64, p = 0.002, r2 = 0.41.

No significant differences pre-and-post training in the control condition.

Food consumption

Intake of Food A (paired with inhibition manipulation) was significantly lower post-training (M = 31.46g, SD = 15.62) compared with pre-training (M = 46.99g, SD = 16.66), p < 0.01No difference in consumption of Food B (paired with impulsivity manipulation) from pre-training (M = 42.30g, SD = 16.14) to post training (M = 43.26, SD = 17.28).

No significant difference in intake of Food C (paired with control manipulation)

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from pre-training (M = 41.87g, SD = 14.33) to post-training (M = 39.89g, SD = 13.29).

Consumption of Food A post-training significantly lower than consumption of Food B, t(18) = -4.25, p < 0.001, ŋp

2 = 0.50.

No difference in consumption of Food B and Food C post-training, t(18) = 1.79, p = 0.30, ŋp

2 = 0.15.(Liu, Zhu et al. 2015)

Training condition20 childrenMean age: 4.87 years (0.26)F: 8; M: 12

Control condition20 childrenMean age: 4.88 years (0.20)F: 10; M: 10

Randomised controlled trial

Not specified Training Type Inhibitory control training

3 weeks, 15 minutes per day, 4 training days per week,12 sessions in total

Training Condition

Commercial game on IPad tablet; “Fruit Ninja”; Food-specific Go/no-go paradigm; respond to fruits (go stimuli) and inhibit responses to bombs (no-go stimuli)

Control condition

3 weeks, 15 minutes day, 2 days per week, 6 sessions in

Inhibition; fluid intelligence; working memory

Pre-post testing

Generic go/no-go task (stimuli not trained)Generic inhibition

Day-night Stroop TasksInference control

Wechsler Preschool and Primary Scale of Intelligence-III (WPPSI-III);digit span subtestWorking memory

Raven’s Colored Progressive Matrices TestNonverbal abstract reasoning

Inhibition

No significant main effects of group for performance on the go-no/go task, F(1, 29) = 0.12, p = 0.727, ŋp

2 = 0.004.

Inference control

No significant main effects of group on the Stroop Task, F(1, 31) = 1.68, p = 0.204, ŋp

2 = 0.051.

Nonverbal abstract reasoning

Significant main effect of group on the Ravens’ task, F(1, 31) = 4.96, p = 0.03, ŋp

2

= 0.14.

Digit span

No significant main effects of group for the digit span task, F(1, 31) = 0.77, p = 0.386, ŋp

2 = 0.02.

46%; Poor

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total

Colour game on IPad tablet

(Porter, Bailey-Jones et al. 2018)

Study 1142 childrenMean age: 7.69 years (1.67)5-11 yearsF: 74% ; M: 26%

Training condition72 childrenMean age: 7.76 years (1.63)F: 53%; M: 47%

Control condition70 childrenMean age: 7.61 years (1.73)F: 51%; M: 49%

Study 2

81 children4-11 yearsMean age: 7.53 years (2.11)

Active food condition29 childrenMean age: 7.60 years (2.29)F: 16; M: 13

Control food condition25 childrenMean age: 7.42 years (2.29)F: 10; M: 15

Control non-food condition27 children

Randomised controlled trial

Not specified Study 1

Type of trainingInhibitory control training

1 training session; 4 blocks of 32 trials

Go/no-go task; 16 food stimuli; 8 healthy images healthy food; 8 images unhealthy food; go signal happy emoticons; no-go signal; sad emoticons

Active food condition (n = 72)Unhealthy foods paired with no-go signalHealthy foods paired with go signal

Control food condition (n = 70)Food stimuli paired with both signal types equally

Study 2

Inhibitory control

Study 1

Post-training

Food choice shopping task; 16 food images (half foods included in training); 8 healthy food; 8 unhealthy food; children asked to selected 8 foods they would most like to eat

Study 2

Pre-post training

Food choice shopping task; 12 food images (8 images of foods closely matched to those included in training); 6 healthy food; 6 unhealthy food; children asked to selected 8 foods they would most like to eat

Post-training

Real food task; 6 snack foods to choose from as participation reward (all foods had appeared in training); half healthy foods; half unhealthy foods

Study 1

Food choice shopping task

Significant effect of condition on number of healthy foods chosen, F(1, 136) = 5.03, p = 0.026, ŋp

2 = 0.036;Participants in the active food condition (M = 4.19, SD = 2.21) chose significantly more healthy foods than participants in the control food condition (M = 3.50, SD = 1.78).

Study 2

Food choice shopping task

Significant main effect of condition was found, F(1, 77) = 5.17, p = 0.008, ŋp

2 = 0.118;Those in the active food condition (M = 3.01, SE = 0.20) chose significantly more healthy foods than those in the control food (M = 2.30, SE = 0.22, p = 0.012) and control non-food condition (M = 2.15, SE = 0.21, p = 0.005).

Significant change in proportion of health foods cards chosen from pre-post training in the active food condition, t(28) = -4.79, p < 0.001, dz = 0.89.

Study 1: 60%; FairStudy 2: 54%; Fair

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Mean age: 7.57 years (2.17)F: 10; M: 17

Type of trainingInhibitory control training

1 training session; 3 blocks of 32 trials

Go/no-go task; see Study 1

Active food condition (n = 29); see Study 1

Control food condition (n = 25); see Study 1

Control non-food condition (n = 27); 8 images of technological games equipment (paired with no-go signal); 8 images of sports equipment (paired with go signal)

No significant change in the control food condition (p = 0.477, dz = 0.14) or control non-food condition (p = 0.353, dz = 0.18) in proportion of health food cards chosen

Real food task

Significant effect of condition on real food task, X2 = 4.76, p = 0.047.

Significant difference found between the active food condition (M = 1.00, SD = 0.76) and the control non-food condition (M = 0.52, SD = 0.67) in healthy foods selected, p = 0.028 .

No differences between active food condition and control food condition and control food control and control non-food condition in healthy foods selected (p > 0.204).

(Soetens and Braet 2007)

45 youngsters with overweightMean age: 14.98 years (1.51)Mean adjusted BMI: 175.76% (25.81)F: 30; M: 15

42 youngsters of normal-weightMean age: 14.74 years (1.81)Mean adjusted BMI: 104.78% (11.80)

Randomised controlled trial

Not specified Experimental condition (24 overweight; 20 normal-weight)Suppression condition; instructed to not think about food or eating

Control condition (21 overweight; 22 normal weight)

Attentional processing; explicit memory

Imbedded Word Task (IWT)Stimuli: 12 high caloric food words; 12 control wordsAttention processing

Recall task; recall words from IWTExplicit memory

Attentional processing

No significant interaction between word content and weight condition in the IWT, F(1, 79) =1.18, p = 0.28.

No significant interaction between word content, suppression condition and weight condition F(1, 79) = 0.31, p = 0.58.

Explicit Memory

54%; Fair

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F: 27; M: 15 Non-suppression condition; instructed to think about anything

Significant interaction between word content and weight condition in the free recall task, F(1, 79) = 7.59, p < 0.01.

Youngsters with overweight participants recalled significantly more food words than control words, t(44) = 5.22, p < 0.001 and recalled significantly more food words than youngsters of normal weight, t(85) = 2.31, p < 0.05.

No significant difference in recall of food words and control words in youngsters of normal weight, t(41) = 1.10, p = 0.28.

No significant interaction between word content, suppression condition and weight condition, F(1, 79) = 0.23, p = 0.63.

(Thorell, Lindqvist et al. 2009)

4-5 yearsMean age: 56 months (5.18)

Working memory training condition17 childrenMean age: 54 monthsF: 8; M: 9

Inhibition training condition18 childrenMean age: 54 monthsF: 9; M: 9

Randomised controlled trial

Randomisation not specifiedPre-post assessments conducted by blind assessor

Type of trainingWorking memory training; inhibition training

Training occurred over a 5-week period, for 15 minutes per day

Working MemoryCondition

Mean number of training days for

Working memory; inhibition; attention; problem solving; response speed

Pre-post training

WAIS-R-NI; Span Board TaskVisuo-spatial working memory

Word Span TaskVerbal working memory

Day-Night Stroop TaskInference control

Go/no-go TaskResponse inhibition

Working memory

Children in the working memory training condition improved significantly on both the visuo-spatial working memory task (p < 0.05) and verbal working memory task (p < 0.01) relative to the control condition.

No significant improvement in visuo-spatial working memory or verbal working memory in those in the inhibitory training condition

46%; Poor

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Active control condition14 childrenMean age: 58 monthsF: 7 ; M: 7

the working memory training condition (M = 23 days, SD = 2.5)

Computer game; visual stimuli presented on computer; child had to remember location and order of stimuli; task difficulty manipulated

Inhibition training condition

Mean number of training days for inhibition training condition (M = 23 days, SD = 2.8)

Computer game; Food-specific Go/no-go paradigm; Food-specific Stop-signal task; Flanker task

Active control condition

Mean number of training days for active control condition (M = 22 days, SD = 3.2)

(commissions); attention (omissions); response speed (reaction time)

NEPSY; auditory continuous performance taskAuditory attention

WPPSI-R; Block Design SubtestProblem solving

relative to those in the control condition (ps > 0.05).

Inhibition

No significant improvement in inference control or errors of commission in children in the working memory training condition or inhibitory training condition relative to those in the control condition (ps > 0.05).

Children in the inhibitory control condition significantly improved their performance on trained tasks including; the go/no-go paradigm (p < 0.01) and Flanker Task (p < 0.05) but not the stop-signal task (p > 0.05).

Attention

Children in the working memory training condition improved significantly on the auditory attention (p < 0.05) and attention as measured by errors of omission on the go/no-go task (p < 0.05) relative to the control condition.

Children in the inhibitory control condition demonstrated no significant improvements in attention relative to the control condition (p values not reported).

Problem solving

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Commercially available computer game

No significant improvement in problem solving in children in the working memory training condition or inhibitory training condition relative to those in the control condition (ps > 0.05).

Response speed

No significant improvement in response speed in children in the working memory training condition or inhibitory training condition relative to those in the control condition (ps > 0.05).

(Verbeken, Braet et al. 2013)

44 children in final phase of a 10-month inpatient treatment program8-14 yearsMean age: 9.79 years (1.09)F: 50%; M: 50%

Training condition22 childrenMean age: 11.50 years (1.60)Admission adjusted BMI: 181.88 (32.65)F: 11; M: 11

Care-as-usual condition22 childrenMean age: 11.41 years (1.93)Admission adjusted BMI: 185.65 (25.06)F: 9; M: 13

Randomised controlled trial

Randomisation using a random number generator by a person blind to the study

Blind assessor for post-test and follow-up measures

Type of trainingExecutive function training

Training condition

25 training sessions over 6 weeks; training sessions were completed 4 times a week and were comprised of two blocks of two training sessions; working memory training task; and inhibition training task

Training was embedded in a game-world ‘Braingame Brian’; each completed block

Executive functioning

Pre training, 1-week post-training

BRIEF; inhibition subscale; working memory subscale; meta-cognition index; total scale (completed by childcare worker)Executive function

Corsi Block-Tapping Task-forward and backwardVisuo-spatial working memory

The Stop TaskInhibition

Pre training, 1-week post-training, 8 weeks and 12 weeks after the treatment program

Height and weightBMI

Diary completed by child; VAS scales of liking of training; less fun (< 5); fun ( >5); and degree to which they tried hard to score well; little hard (<2.5); hard ( > 2.5)Training acceptability

Executive functioning

No significant time by condition interaction effect on the BRIEF inhibition scale, F(1, 41) = 0.57, p > 0.05, ŋ2= 0.01.

Significant condition by time interactions on the BRIEF working memory subscale F(1, 41) = 4.54, p < 0.05, ŋ2 = 0.10 and meta-cognition index F(1, 41) = 5.57, p < 0.05, ŋ2 = 0.12.

No significant time by condition interaction effect on the BRIEF total scale, F(1, 41) = 3.33, p > 0.05, ŋ2= 0.08.

Visuo-spatial working memory

Significant condition by time interaction effect for Corsi Block-Tapping forward, F(1, 40) = 5.75, p ≤ 0.05, ŋ2 =

69%; Good

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of training tasks child received an elaboration of game-world or extra powers for Brian (main character of game)

Working memory training task; reproduction of sequence of rectangles (length of sequence is adapted)

Inhibition training task;Generic Go/no-no task

Care-as-usual condition

Teaching of healthy food choices; providing the opportunity to engage in daily physical activity; and provision of Cognitive Behavioural Techniques

0.13 and Corsi Block- Tapping backward, F(1, 40) = 5.22, p ≤ 0.05, ŋ2 = 0.12.

Inhibition

No significant time by condition interaction effect for inhibition, F(1, 40) = 0.02, p > 0.05, ŋ2 = 0.00.

Weight Loss

Significant time by condition interaction for adjusted BMI F(1, 38) = 3.58, p ≤ 0.05, ŋ2

= 0.22;Children in the training condition demonstrated significantly greater weight loss from post-test to 8-weeks follow-up than those in the care-as-usual condition, F(1,40) = 7.75, p ≤ 0.01, ŋ2 = 0.16.No significant between-group difference in weight loss from 8 weeks to 12 weeks follow up, F(1, 40) = 0.54, p > 0.05, ŋ2 = 0.01.

Treatment acceptability

94.74% tried hard to score well during the training tasks; M = 4.18, SD = 0.8244% reported that the training sessions were fun; M = 5.95, SD = 2.72.

(Verbeken, Boendermaker et al. 2018)

40 children attending 10-months inpatient obesity treatment programMean age: 12.58 years (1.43)F: 52.5%; M: 47.5%

Randomised controlled trial

Randomisation using a random number generator by a person blind to the study

Type of trainingApproach-avoidance training (AAT)

Training condition

Approach bias; attention bias; implicit association bias

Pre-post training

Approach/avoidance task; stimuli; 10 pictures of health food; 10 pictures of unhealthy food; 10

After each training session

Acceptability of computer task on 5 point Likert Scales;Liking scale (very

Approach bias; attentional bias; adjusted BMI

No significant (ps > 0.30) between-group differences in mean changes from pre-post training in attention

63%; Fair

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Training condition21 participantsMean age: 12.38 (1.63)Adjusted BMI = 145.77% (22.30)F: 12; M: 9

Control condition19 participantsMean age: 12.79 (1.18)Adjusted BMI: 136.69% (16.06)F: 9; M: 10

Blind assessor for post-test and follow-up measures

10 sessions over 4-weeks; sessions were comprised of 2 training blocks

AAT embedded in game; earn points for correct responses; points used to build virtual cities; social element

Stimuli: 8 pictures of healthy food; 8 pictures of unhealthy food

Unhealthy pictures push (avoid)Healthy pictures pull (approach)

Control Condition

Tetris computer game

pictures of neutral stimuliAttentional bias

Implicit association task; stimuli: pleasant words; unpleasant words and unhealthy food wordsImplicit association bias

Visual probe task; stimuli: heathy and unhealthy food picturesAttentional bias

Height and weightAdjusted BMI

nice to very boring) and difficulty scale (very difficult to very easy)

bias for unhealthy food; training condition (M = 5.94, SD = 46.61); control condition (M = 16.31, SD = 56.58); approach bias for unhealthy food; training condition (M = 73.61, SD = 123.97); control condition (M = 47.38, SD = 146.15); approach bias for healthy food; training condition (M = 47.06, SD = 85.26); control condition (M = 69.82, SD = 152.72; adjusted BMI; training condition (M = -7.37, SD = 4.19); control condition (M = -8.35, SD = 4.29).

Significant decrease in approach bias toward unhealthy food (p = 0.022) and toward healthy food (p = 0.032) pre-to-post training in the training condition, no significant change in control condition.

Implicit association bias

No significant (ps > 0.30) between-group differences in mean changes from pre-post training in implicit association bias; training condition (M= -0.04, SD = 0.58); control condition (M = 0.03, SD = 0.51).

Training acceptability

Liking of training (M = 2.80, SD = .92)Difficult of training (M = 3.30, SD = 1.06)

(Verbeken, Braet et al.

36 youngsters of an inpatient obesity

Randomised controlled trial

Not specified Type of trainingInhibition;

Inhibition; attentional

Pre-post training FeasibilityAttrition rates

Cognitive training effects 52%; Fair

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2018) treatment program of a rehabilitation centre9-15 yearsMean age: 12.06 years (1.47)F: 52.8%; M: 47.2%

Training condition21 participantsMean age: 12.00 years (1.55)Adjusted BMI = 136.18% (18.78)F: 9; M: 12

Control condition15 participantsMean age: 12.00 years (1.41)Adjusted BMI = 130.67% (18.59)F: 7; M: 8

attentional bias; approach bias6 sessions over 5 weeks

Three training tasks (all tasks trained 4 times; 2 tasks a session);

1. Inhibition trainingGo/no-go paradigm Stimuli; healthy or unhealthy food pictures

Training condition-Go-related letter cue paired with healthy food picturesNo-go letter cue related with unhealthy food pictures

Control condition- letter-cues matched 50/50 with healthy and unhealthy food pictures

2. Attentional trainingVisual probe attention

bias; approach bias

Go/no-go paradigmIdentical paradigm used during control condition trainingFood-related inhibition

Visual-probe attention taskIdentical paradigmused during control condition trainingAttentional bias

Approach/avoidance taskIdentical paradigmused during control condition trainingApproach bias

Behaviour Rating Inventory of Executive Functioning BRIEF; inhibition subscaleInhibition

Self-report version of the BRIEF-SR; inhibition subscaleInhibition

Height and weightBMI

No significant between-group differences in approach bias toward unhealthy foods (ŋp

2= 0.006); attention bias towards unhealthy foods, (ŋp

2= 0.004); mean reaction times for healthy (ŋp

2 < 0.001) and unhealthy foods (ŋp

2 < 0.001) on the go trials.

Inhibition

Significant interaction between time and condition F(1, 34) = 12, 343, p = 0.001 (ŋ2= 0.26) on the BRIEF inhibition subscale;Inhibition scores significantly decreased in training condition from pre-training (M = 15.524, SD = 1.125) to post-training (M = 14.286, SD = 1.165).Inhibition increased in control group from pre-training (M = 18.133, SD = 1.331) to post-training (m = 19.267, SD = 1.379).

BRIEF-SR inhibition subscale no significant interaction effect (F < 1; p = .928).

Weight

No significant interaction between time and condition on weight, F(1, 34) = 0.765, p = .388, ŋp

2 = 0.02.

Significant main effect of time, p = 0.009, ŋp

2 = 0.247;Significant difference in

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task;presented series of pictures of healthy and unhealthy foods, arrow presented on one picture

Training condition- arrow always appeared on healthy food

Control condition -matching of arrow placement and content of pictures was 50/50

3. Approach biasStimuli: healthy and unhealthy foods

Training condition-Unhealthy food tilted to right – instructed to press up key; pictures zooms out (avoid)Healthy food tilted to left – instructed to press down

weight between pre-training and post-training, p = .000.Significant difference in weight between post-training and follow-up, p = .035.No significant difference in weight between pre-training and follow-up, p = .433.

Feasibility

93% of participants completed the training program

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key; pictures zooms in (approach)

Control condition-matching between tilt and content of pictures was 50/50

(Warschburger, Gmeiner et al. 2018)

59 participants8-16 yearsOverweight or obeseF: 33; M: 26

Explicit training condition30 participants

Implicit training condition29 participants

Randomised controlled trial

Cluster randomisation

Type of trainingApproach-avoidance training (AAT)

6 sessions over two weeks (first 4 daily basis, remaining sessions after break of 2-3 days)

AAT-20 photographs of high-energy snacks and 20 pictures of vegetables

Implicit training React to shape of plate-push square plates (snacks) pull circular plates (vegetables)

Explicit trainingReact to type of foodPush snacks, pull vegetables

Approach tendencies; implicit associations

Pre-post training

AAT response latencies (trained stimuli)Compatibility scores calculated; positive values corresponding to intended training effect (push snacks, pull vegetables)

Implicit Association Test (stimuli not trained)7 images of high energy snacks, 7 images of positive and negatively valenced wordsImplicit associations

Height and weightBMI-SDS

Rating of general liking of training on 5-point Likert scaleAcceptance of AAT

Approach-avoidance tendencies

Compatibility scores for snacks and vegetables; significant main effect of time (p < 0.001, ŋ2 = 0.18); no main effect of training condition (p = 0.375, ŋ2 = 0.01) or interaction between time and training condition (p = 0.383, ŋ2 = 0.01).

Compatibility scores for snacks; significant main effect of time (p < 0.001, ŋ2= 0.290, and interaction between time and training condition (p < 0.001, ŋ2 = 0.14), no main effect of training condition (p = 0.39, ŋ2= 0.01)

Compatibility scores for vegetables; no significant main effects of time (p = 0.53, ŋ2= 0.08), training condition (p = 0.66, ŋ2= 0.00) or interaction between time and training condition, (p = 0.133, ŋ2= 0.04).

Significant increases in compatibility scores were identified only for the first

58%; Fair

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two sessions with large effect sizes; session 1 F(1, 54) = 18.11, p < 0.001, ŋ2= 0.25; session 2 F(1, 54) = 9.98, p = 0.003, ŋ2= 0.16.

Change in compatability scores was not significantly correlated with BMI-SDS ( r = 0.19, p = 0.165).

Implicit association

No significant changes in implicit association over timeF(1, 54) = 0.14, p = 0.712.No significant effect of training condition on implicit association F(1, 54) = 0.08, p = 0.773, or interaction between time and training condition F(1, 54) = 0.04, p = 0.837.

Post-training compatibility scores were negatively correlated with post training IAT scores , r = -0.29, p = 0.03.

No significant correlations between implicit association and BMI-SDS, pre (r = 0.20, p = 0.139) or post training (r = -0.02, p = 0.861).

Training acceptability

Mean liking score of the training was 2.46 (1.04)

Mean liking score of the explicit condition (M = 2.73, SD = 0.98) was higher than that of the implicit condition

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(M = 2.17, SD = 1.04).

Significant correlation between acceptance scores and change in compatibility scores (r = 0.30, p = 0.02).

(Warschburger, Gmeiner et al. 2018)

232 children and adolescentsinpatients for obesity treatment8-16 yearsMean age: 13.09 years (1.84)BMI-SDS = 2.7 (0.47)F: 53.9%; 46.1%

Participants demographics not reported for each group (no significant differences between groups)

Randomised control trial

Not specified Type of trainingApproach-avoidance training

6 sessions over two weeks

AAT training condition

Vegetables pictures placed on circular plates instructed to pull plate towards them (approach)Snack pictures placed on square plates instructed to push plate away (avoid)

Control condition

Vegetable and snack pictures presented equally on circular and square plates

Implicit association bias; attention bias; response inhibition; eating behaviours

Pre-post training

Modified Implicit Association TestStimuli (not trained); high-calorie snacks; neutral objects; attributes with positive/negative valenceImplicit association bias

Modified dot probe taskStimuli (not trained); high-calorie snack pictures and non-food picturesAttention bias

Stroop testComputer-based ( ≥ 12 years); stimuli (not trained); fruits and vegetables Paper-and-pencil (<12 years); stimuli; colour wordsResponse inhibition

Pre-training, post training, 6-month follow-up, 12-months follow-up

Food consumption based on list of food items

Approach-avoidance bias

Significant time by group interaction for approach-avoidance bias reaction time p = 0.023, ŋ2= 0.02;Training group baseline (M = 65.37, SD = 229.37); post-training (M = 105.14, SD = 199.91); control condition (M = 43.81, SD = 233.85); post-training (M = -4.23, SD = 188.85).

Significant time by group interaction for approach-avoidance bias error rate; p = 0.01, ŋ2= 0.03Training group; baseline (M = 0.01, SD = 0.15); post-training (M = 0.01, SD = 0.16); control condition; baseline (M = 0.08, SD = 0.35); post-training (M = -0.03, SD = 0.14).

Implicit Association Bias

No significant effect of training on implicit association bias, p = 0.55, ŋ2 <0.01.

Attention bias

No significant effect of training on attention bias, p = 0.126, ŋ2 = 0.01.

63%; Fair

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Problematic, unproblematic food consumption

Brief Self-Control ScaleSelf-control

German Eating Disturbance QuestionnaireDisinhibition of eating due to internal and external cues

Height and weightBMI-SDS

Inhibition

No significant effect of training on computer based F (1,141) = 0.95, p = 0.332, or paper and‐pencil‐based inhibition measures, F (1,72) = 1.07, p = 0.305.

Eating behaviours/weight-related outcomes

Significant effect of training on problematic food consumption at 6-months (p = 0.014, ŋ2= 0.05) but not at 12-months (p = 0.331, ŋ2= 0.01).

Significant effect of training on self-control at 6-months (p = 0.011, ŋ2 = 0.05) but not at 12-months (p = 0.19, ŋp= 0.01).

No significant effect of training on BMI-SDS at 6-months (p = 0.115, ŋ2= 0.02) or 12-months (p = 0.276, ŋ2

= 0.01.

No effect of training on disinhibited eating at 6-months (p = 0.495, ŋ2 < 0.01) or 12-months (p = 0.341, (ŋ2= 0.01).

(Zhao, Chen et al. 2015)

30 children

15 children in training conditionMean age: 10.07 years (1.28)F:8; M:7

15 children in control condition

Randomised controlled trial

Randomly assigned according to last 2 digits of participant’s student number

Details of blinding not specified

Type of TrainingInhibitory response modification

Training occurred for 20 minutes on 7 consecutive days; sessions

Response inhibition; inference control

Pre-post training

Go/no-go taskResponse inhibition

The stroop colour-word inference taskInference control

Inhibition

Post-training (M = 8.67, SD = 7.15) children in the training condition made significantly fewer errors of omission than pre-training (M = 12.60, SD = 7.66), p ≤ 0.01.No significant change in

48%; Poor

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Mean age: 10.60 years (1.35)F:8; M:7

comprised of 7 blocks of 30 trials

Training condition

Execution of response to command if followed by verbal expression “Wesley says”; inhibition of response if not followed by command

Control condition

Children participated in extracurricular activities unrelated to training game

control condition, p > 0.05.

Post-training (M = 7.93, SD = 7.51) children in the training condition made significantly fewer errors of commission than pre-training (M = 13.27, SD = 8.10), p ≤ 0.01.No significant change control condition, p > 0.05.

Inference control

No significant within-group changes or between-group differences in inference control reaction time.

No significant within-group changes or between-group differences in inference control accuracy.

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Kittel, R., Schmidt, R., & Hilbert, A. (2017). Executive functions in adolescents with binge-eating disorder and obesity. The International Journal of Eating Disorders, 50(8), 933-941. doi:https://dx.doi.org/10.1002/eat.22714

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Levitan, R. D., Rivera, J., Silveira, P. P., Steiner, M., Gaudreau, H., Hamilton, J., . . . Team, M. S. (2015). Gender differences in the association between stop-signal reaction times, body mass indices and/or spontaneous food intake in pre-school children: an early model of compromised inhibitory control and obesity. International Journal of Obesity (2005), 39(4), 614-619. doi:https://dx.doi.org/10.1038/ijo.2014.207

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Mehl, N., Bergmann, S., Klein, A. M., Daum, M., von Klitzing, K., & Horstmann, A. (2017). Cause or consequence? Investigating attention bias and self-regulation skills in children at risk for obesity. Journal of Experimental Child Psychology, 155, 113-127. doi:https://dx.doi.org/10.1016/j.jecp.2016.11.003

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Miller, A. L., Rosenblum, K. L., Retzloff, L. B., & Lumeng, J. C. (2016). Observed self-regulation is associated with weight in low-income toddlers. Appetite, 105, 705-712. doi:https://dx.doi.org/10.1016/j.appet.2016.07.007

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Nazarbol, N., & Fath, N. (2015). The role of BMI in predicting emotion-driven impulsivity and sensitivity to reward/punishment in over-obese adolescents. Biomedical and Pharmacology Journal, 8SE, 729-737. doi:10.13005/bpj/776

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Nederkoorn, C., Jansen, E., Mulkens, S., & Jansen, A. (2007). Impulsivity predicts treatment outcome in obese children. Behaviour Research and Therapy, 45(5), 1071-1075.

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Pauli-Pott, U., Albayrak, O., Hebebrand, J., & Pott, W. (2010b). Does inhibitory control capacity in overweight and obese children and adolescents predict success in a weight-reduction program? European Child & Adolescent Psychiatry, 19(2), 135-141. doi:https://dx.doi.org/10.1007/s00787-009-0049-0

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Pentz, M. A., Spruijt-Metz, D., Chou, C. P., & Riggs, N. R. (2011). High Calorie, Low Nutrient Food/Beverage Intake and Video Gaming in Children as Potential Signals for Addictive Behavior. International Journal of Environmental Research and Public Health, 8(12), 4406-4424. doi:10.3390/ijerph8124406

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Schmitt, S. A., Korucu, I., Jones, B. L., Snyder, F. J., Evich, C. D., & Purpura, D. J. (2017). Self-regulation as a correlate of weight status in preschool children. Early Child Development and Care, 1-11. doi:10.1080/03004430.2017.1299715

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