Pancosma, the pioneering Swiss company in the field of additives has launched the first and only 100% plant extracts product recognized by the EU commission as a zootechnical additive for broilers. This natural growth promoter is designed to increase weight gain in birds, to constantly reduce FCR and to improve final carcass quality. A standard of excellence developed on Pancosma’s 4 company values: transparency, safety, traceability and full efficacy.

www.pancosma.com

APPROVED ZOOTECHNICAL ADDITIVE

6930

PANCOSMA SA Voie des Traz, 6

1218 Le Grand Saconnex Switzerland

Subject: Pancosma brings to market the first 100% plant extract product approved as a zootechnical additive for broilers in the EU. Dear customers and partners

Pancosma is pleased to announce that the leading product XTRACT® 6930, has now achieved a new and unique status within the EU, branded as Xtract Evolution B.

The strict European addit ive classificat ion system has 5 different legal categories: . Technologic addit ives (e.g: emulsifiers, acidif iers…) . Nutrit ional addit ives (e.g.: vitamins, minerals…) . Sensorial addit ives (e.g.: flavors, plant extracts…) . Zootechnical addit ives (e.g.: enzymes, pre/ probiot ics...) . Coccidiostats

In order to pursue its differentiation strategy within the phytonutrient market, Pancosma in 2009

started the challenging process to upgrade XTRACT® 6930 from a sensorial to a zootechnical

category. Until now, no phytonutrient have been registered in the zootechnical category.

To achieve this goal, Pancosma submitted to EFSA (European Food Safety

Authority) a complete dossier detailing product standardization, manufacturing

process, traceability tests in pure form and in feed, toxicology studies and

performance trials in broilers.

After EFS A released their posit ive scient if ic opinion in February 2015, the EU commission approved XT RAC T® Evo lut ion-B (Xtract 6930) as a zootechnical addit ive and performance enhancer, havingpositive and consistent effects on broiler performance when used at 100 g/ t of feed. This official regulation is public and codif ied under Reg. No. 2015/ 1490. The registered product XTRAC T® Evolut ion-B ( product code: X60-6930) is now t raceable with the E number 4.d.11 in the EU.

IMPORT ANT: The use of this zootechnical registered addit ive in poultry feed or premixes, together with the advantage of being able to claim performance enhancements, is subject to a compulsory declaration on your feed and/ or premix labels displayed in the market. The E number (4.d.11) and the dosage should clearly and easily be identified by local authorit ies. fgfgfgggrgrg The Pancosma team remains at your disposal for any addit ional information you may need. We thank you for your continued loyalty.

My best regards

Jennifer MAURIN – Product Manager

6930

NEW ZOOTECHNICAL ADDITIVEEFSA & EU Commission acknowledge:The efficacy of XTRACT® Evolution-B (Xtract 6930), at a dose of 100 g/t of final broiler feed is approved by EU commission!

The efficacy of the product has been approved by EFSA and is brand specific.XTRACT® EVOLUTION-B is a micro encapsulated, standardised combination product of active substances naturally occurring in aromatic plants and spices, selected for their proven effects in broilers.

• Improvement of growth• Improvement of feed efficiency• Improvement of metabolizable

energy

Cinnamaldehyde  (3%)  

Carvacrol  (5%)  

Capsicum  oleoresin  (2%)  

PROCESS FOR OBTAINING A ZOOTECHNICAL FEED ADDITIVE REGISTRATIONA long process of differentiation

REGISTRATION REQUIREMENTS

Data collection Answering questions

OCTOBER 2009Strategic decision is taken by Pancosma

Characterisation• Raw materials• Manufacturing process• Final product• Stability assays

*EURL: European Union Reference laboratory

Section 1 Section 2 Section 3

Safety• Methods of analysis with EURL*• Consumer safety• Environmentalevaluation• Animal safety & residues intissue

Efficacy• 4 controlled performance trials• Animal product quality

OCTOBER 2013EFSA started theDossier’sevaluation

FEBRUARY 2013Dossier submissionto the EFSA

SEPTEMBER 2015 Official Journal publication OJ 2015/1490 XTRACT® is approved

FEBRUARY 2015EFSApositivescientificopinion is released

EFFICACY TRIALSOutcomes overview – New meta analysis

Submitted trials to EFSA – Example 1: Ross PM3

Improvement  of    AME  

7  comparisons  

Improvement  of    GROWTH  

20  comparisons    

Improvement  of    FEED  EFFICIENCY  

20  comparisons  

1,60  

1,62  

1,64  

1,66  

1,68  

1,70  

1,72  

FCR  (g/g)  

47  

48  

49  

50  

51  

ADG  (g/d)  

3200  

3250  

3300  

3350  

AMEn  (kcal/kg)  

Oguey et Bravo. PSA 2015

8  

2084  

2115  

2065  

2075  

2085  

2095  

2105  

2115  

EFSA  Journal  2015;13(2):4011,  trial  2    Technical  BulleCn  05  XTR004  .  Please  note  slight    

between  docs.  differences  due  to  staCsCcal  analysis      

a,  b,  P  <0.05  

Final  body  weight    at  d.  36  (g/birds)  

a    

b    

1,62  

1,6  

1,55  

1,57  

1,59  

1,61  

1,63  

1,65  

a    

b    

Feed  to  Gain  at  d.  36  

NegaCve  control  XTRACT®    

0%  

1%  

2%  

3%  

4%  

5%  

6%  

7%  

8%  

9%  

Mortality  +  Culled  (%)  

-­‐  25  %  

+ 4.5%P < 0.001

-3.9%P < 0.001

+ 2.4% P < 0.001

EFSA Journal 2015;13(2):4011, trial 2 TechnicalBulletin05XTR004.Pleasenoteslight

differencesbetweendocsduetostatisticalanalysis.

EFFICACY TRIALSSubmitted trials to EFSA – Example 2: Arbor Acres

New data on carcass quality

2084  

2206  

2000  

2050  

2100  

2150  

2200  

2250  

2300  

 EFSA  Journal  2015;13(2):4011,  trial  4  

Technical  BulleAn  07  XT-­‐TS  13  (focusing  only  on    carcass  quality)  

a,  b,  P  <0.05  

Final  body  weight    at  d.  35  (g/birds)  

a    

b    

2,66  

1,6  

1,5  

1,7  

1,9  

2,1  

2,3  

2,5  

2,7  

2,9  

a    

b    

Feed  to  Gain  at  d.  35  

NegaAve  control  XTRACT®    

0%  

1%  

1%  

2%  

2%  

3%  

3%  

4%  

Mortality  +  Culled  (%)  at  d.  35  

b    

1,45  

1,18  

0,00  

0,50  

1,00  

1,50  

2,00  

Abdominal  fat  (%)  

Awaad  et  al.,  2014  

17,4  

18,84  

16,5  

17  

17,5  

18  

18,5  

19  

Breast  meat  (%)  

-­‐  19%  P  <  0.01  

31,65   33,35  

0  

10  

20  

30  

40  

50  

Carcass  meat  (%)  

+  5.3  %  P  <  0.03  

+  8.3  %  P  <  0.01  

a,  b,  P  <0.05  

NegaFve  control  XTRACT®    

3,0

0.5

2084

2206

2000

2050

2100

2150

2200

2250

2300

a

b

MODE OF ACTIONS - BASICHow to get better performance?

Stimulation of enzymes secretions &/or activitiesGanesh & Bhat et al., 1984Jamroz et al., 2005Hernandez et al., 2004Bravo, Pirgozliev et al., 2014etc.

Anti-oxidant & anti inflammatory effects protecting gut epitheliumAwaad et al., 2014Garcia et al., 2007Karadas, Pirgozliev, Bravoet al., 2014Kim et al., 2010etc.

DIGESTIBILITY ENHANCER

NUTRIENTS ABSORPTION

The first 100% plant extracts product for broilers upgraded to zootechnical category in EU

www.pancosma.com

ACTIVELY BETTER

Growth: + 4.5 %FCR: - 3.9 %AME: + 50 kcal/kgAsk for our new meta analysis

Continue to define the nutraceutical frontier

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TECHNICAL SALES MANAGERcell: +27 (0) 72 037 0749email: frans@alliednutrition.comskype: frans.hagg

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