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1
ANTERIOR
CRUCIATE
LIGAMENT
Prevalence
1 out of every 3000 people will suffer an
ACL injury per year.
Approximately 100,000 ACL
reconstructions are performed annually.
Miyasaka KC, et al. The incidence of knee ligament injuries in the
general population. Am J Knee Surg 1991;4:3-8.
Cavanaugh J. Anterior Cruciate Ligament Reconstruction. In:
Postsurgical Rehabilitation Guidelines for the Orthopedic
Clinician. Mosby, St. Louis, 2006.
Prevalence
Disrupted more than any other ligament in
the body
Johnson R. Prevention of cruciate ligament injuries. In: Feagin JJ
(ed). The Crucial Ligaments: Diagnosis and Treatment of
Ligamentous Injuries about the Knee. New York, 1988. Churchill
Livingstone.
2
ACL Reconstruction Cost
Variance
Archibald-Seiffer N, et al. Review of anterior cruciate ligament reconstruction cost variance
within a regional health care system. Am J Sports Med. 2015;43(6):1408-1412.
Archibald-Seiffer N, et al. Review of anterior cruciate ligament reconstruction cost variance
within a regional health care system. Am J Sports Med. 2015;43(6):1408-1412.
Function of the ACL
Primary restraint to anterior displacement of
tibia relative to the femur
Secondary stabilizer of rotation, mainly
with internal and external tibial rotation
Cruciates cross with tibial internal rotation
3
Ligament Restraints
ACL provides 85% of restraint to anterior displacement of
tibia between 30-90 degrees of knee flexion
Secondary Restraints – remaining 15%
ITB 25%
Mid 1/3 medial capsule 22%
Mid 1/3 lateral capsule 20%
MCL 16%: LCL 12%
Butler DL, Noyes FR, Grood ES: Ligamentous restraints to anterior-posterior drawer in the
human knee: a biomechanical study, J Bone Joint Surg Am 62:259-270, 1980.
Grood ES, Suntay WJ, Noyes FR, Butler DL: Biomechanics of the knee-extension exercise:
effect of cutting the anterior cruciate ligament, J Bone Joint Surg Am 66:725-734, 1984.
Minimum 5 year FU
1820 patients
78% - 1415 patients
75 (5.3%) had injury
to other knee
61 (4.3%) had injury
to reconstructed knee
Shelbourne KD, Gray T, Haro M. Incidence of subsequent injury to either
knee within 5 years after anterior cruciate ligament reconstruction with
patellar tendon autograft. Am J Sports Med 2009;37(2):246-251.
Women suffered more injuries than men to
contralateral knee (7.8% to 3.7%)
Injuries to reconstructed knee not significantly
different (4.3% vs 4.1%)
No difference in those returning to sports
sooner than 6 months compared to those after
6 months
Risk
17%<18
7% 18-25
4% > 25
Shelbourne KD, Gray T, Haro M. Incidence of subsequent injury to either
knee within 5 years after anterior cruciate ligament reconstruction with
patellar tendon autograft. Am J Sports Med 2009;37(2):246-251.
4
Anatomy
Intercondylar notch
A-shaped notch – higher risk for ACL
injury
With ER ACL gets caught against notch
and is cut by LFC
Uhorchak JM, et al. Risk factors associated with non-contact injury of the
anterior cruciate ligament: a prospective four-year evaluation of 859 West
Point cadets. Am J Sports Med 2003;31(6):831-842.
Anatomy
Intercondylar notch
Others though cast doubt that notch size
contributes to ACL injury
Schickendantz MS, Weiker GG. The predictive value radiographs in the
evaluation of unilateral and bilateral anterior cruciate ligament injuries.
Am J Sports Med 1993;21(1):110-113.
Teitz CC, et al. Symmetry of the femoral notch width index. Am J Sports
Med 1997;25(5):687-690.
Intercondylar Notch
615 male professional basketball players
NBA combine workouts between 1992-
1999
NBA league-wide injury database used to
identify injured players
Notch width index did not predict rate of
ACL injury
Lombardo S, Sethi PM, Starkey C. Intercondylar notch stenosis is not a
risk factor for anterior cruciate ligament tears in professional male
basketball players . Am J Sports Med 2005;33(1):29-34.
5
Anatomy
Q-angle
Those who sustained ACL injury
displayed significantly larger Q-angle
than those that did not sustain injury
Shambaugh JP, et al. Structural measures as predictors of injury in
basketball players. Med Sci Sports Exerc 1991;23(5):522-527.
Anatomy
Notchplasty
Before 1988 done only to increase visualization
of intercondylar area
Noticed upon subsequent arthroscopy that the
lateral aspect of graft became frayed
Now routinely take 11 mm for standard 10 mm
graft
Shelbourne KD and Trumper RV. Anterior Cruciate Ligament
Reconstruction: Evolution of Rehabilitation. In: Ellenbecker TS
(ed). Knee Ligament Rehabilitation. Churchill Livingstone 2000.
Anatomy
Absolute Size of ACL
Volume calculated via
MRI scans
27 noninjured knees of
those injured with
noncontact ACL injury
27 age matched controls
Chaudhari AMW, et al. Anterior cruciate ligament injured subjects
have smaller anterior cruciate ligaments than matched controls. A
MRI Study. Am J Sports Med 2009;37(7):1282-1287.
6
Anatomy
Contralateral volume for
injured subjects was
significantly smaller than
non injured subjects
Injured group volume =
1921 mm3
Uninjured group volume =
2151 mm3
Chaudhari AMW, et al. Anterior cruciate ligament injured subjects
have smaller anterior cruciate ligaments than matched controls. A
MRI Study. Am J Sports Med 2009;37(7):1282-1287.
ACL – Where Does It Fail
80% Mid Substance
18% Femur
2% Tibia
Younger patients often have an avulsion of
the tibial spine which is the insertion of the
ACL
ACL
35mm long
Stretches 10-12 mm
(1/3 increase) before it
ruptures
7
ACL
> 50% disruption
> 50% risk of
progression to
complete failure
Noyes FR, et al. Partial tears of anterior cruciate ligament.
Progression to complete ligament deficiency. J Bone Joint Surg.
1989;71B:825-833.
Mechanism of Injury
Combined valgus and
external rotation
applied to the knee
while the the foot is
firmly planted.
Mechanism of Injury
Non contact external
rotation
8
Mechanism of Injury
Excessive internal
rotatory force or
combination of
internal rotation and
hyperextension
Mechanism of Injury
Hyperextension
Perception of knee
“giving out”
Mechanism of Injury
Most injuries are noncontact injuries in
which sudden limb deceleration
accompanied by contraction of the
quadriceps muscle group
Football player planting and cutting
Basketball player catching a pass and
planting to cut toward basket
9
Mechanism of Injury
6 experts visually examined 39 videos of
ACL injury situations
72% did not involve contact
>50% of women injured pushed just before
injury
Perturbation may have influenced injury
Krosshaug T, et al. Mechanisms of anterior cruciate ligament injury in basketball. Am J Sports Med 2007;35(1):359-367.
Mechanism of Injury
Knee flexion angles at injury were higher in
males than females
Females 5.3 times higher risk of sustaining
valgus collapse
Preventive programs should include
distractive elements
Krosshaug T, et al. Mechanisms of anterior cruciate ligament injury in basketball. Am J Sports Med 2007;35(1):559-367.
Injury From External Contact
O’Donoghue “unhappy triad”
Combination of valgus, flexion, and external rotation applied to knee while foot is planted
Injury to ACL, MCL and Medial Meniscus (Lateral meniscus?)
10
Lateral Meniscus!
Shelbourne KD, Nitz PA. The O’Donoghue triad revisited: combined knee injuries involving anterior cruciate and medial collateral ligament tears. Am J Sports Med. 1991;19:474-477.
Barber F. Snow skiing combined anterior cruciate ligament/medial collateral ligament disruptions. Arthroscopy. 1994;10:85-89.
Barber F. Accelerated rehabilitation for meniscus repairs. Arthroscopy. 1994;10:206-210.
Duncan JB, et al. Meniscal injuries associated with acute anterior cruciate ligament tears in alpine skiers. Am J Sports Med. 1995;23:170-172.
Physical Examination
Patient usually feels and hears a “pop”
(80-90%)
Acute hemarthrosis develops within 12
hours
Factors Determining Treatment
Choices Access to rehab facility
4 week lag time
Surgery on acutely injured knee will lead to
decreased ROM and impaired function
One month prior to surgery begin PRE-HAB
Increase strength
Increase ROM
Decrease swelling
11
Surgical Procedures
Ideal Operation:
Fixation:
Screws rather than sutures
Bone-IPT-bone better fixation
Excellent strength
Allows immediate motion
Permits early activity
Prevent recurrence
Primary Repair
Original tissue is repaired back to itself
Poor long term results for intra-substance tears
repaired as an isolated procedure
Rupture affects blood supply
Medial intragenicular artery injured
Tissue becomes necrotic
Decreases integrity of graft
Appropriate only when true avulsion occurs
Indications for Primary Repair
True avulsion
Usually occurs in teens
Ligaments stronger than bones
Epiphyseal growth plate open
Fixation of bony fragment with screw
Sedentary individuals
Older individuals – less active
Partial ACL rupture with minimal instability
12
Primary Repair with Marrow
Stimulation
99 patients
26 treated with
primary repair of
proximal ACL tears
Marrow stimulation
via microfracture at
femoral footprint
Gobbi A, et al. Primary repair combined with bone marrow stimulation in acute
anterior cruciate ligament lesions. Am J Sports Med. 2009;37(3):571-578.
Primary Repair with Marrow Stimulation
Gobbi A, et al. Primary repair combined with bone marrow stimulation in acute
anterior cruciate ligament lesions. Am J Sports Med. 2009;37(3):571-578.
Gobbi A, et al. Primary repair combined with bone marrow stimulation in acute
anterior cruciate ligament lesions. Am J Sports Med. 2009;37(3):571-578.
13
Primary Repair with Marrow Stimulation
25 month follow up (17-38 mo)
Subjective scales lower (improved)
following procedure
Ligament laxity different
3.5 mm pre - 1.3 mm post
Gobbi A, et al. Primary repair combined with bone marrow stimulation in acute
anterior cruciate ligament lesions. Am J Sports Med. 2009;37(3):571-578.
Reconstructive Procedures
Replace original graft
Infrapatellar Tendon (IPT)
Extra-articular structure becomes an intra-
articular structure
Rejection phase
May create a synovitis response
This can lead to decreased blood supply
Different Procedures
Autograft: own tissue
Allograft: from “tissue bank”
Synthetics: man made tissue
14
Ligament Substitutions
Increased tensile strength
Increased fatigue strength
Decreased immunogenicity
Easy to install
Allows early rehab and return to activity
Allows biological ingrowth
Isometricity/Physiometry
Constant tension on ligament throughout
ROM
The ideal placement for intra-articular grafts
Improper placement is most common cause
of surgical failure
Autograft
Patellar tendon
Bone-IPT-bone procedure
Gold standard
Central 1/3 of IPT (10mm) on average
Semitendinosis/gracilis
Double, triple or quadruple looped for reinforcement
Iliotibial band/Quadriceps tendon
Not used very often
15
Patellar Tendon Autograft
Advantages
Readily available
Excellent strength
Best well documented long term results
Allows most aggressive rehab of all biological tissue secondary to strength and bone-bone healing
Patellar Tendon Autograft Disadvantages
Weakens extensor mechanism (?)
Associated risks
Patellar chondrosis
Tendinitis
ROM deficits
Patellar fracture
Tendon rupture
Requires diligent rehabilitation
IPCS may result
Excessive proliferation of scar tissue secondary to vascular supply
Patellar Tendon Autograft
Anatomic/pathologic limitations
Small/narrow tendon
Chronic tendinitis
Reduced performance in some jumping
sports
16
Surgical Technique
Bone-central 1/3 tendon-bone
Free graft, nothing attached
Procedures
Open reconstruction
Arthroscopically assisted procedure: Hole drilled out through femur, screw fixation from outside
Endoscopic technique: Do not drill all the way out of femur, screw fixation from inside
Semi-T, Gracilis
Tendon
Semi-T/Gracilis Autograft
Advantages
Readily available
Double/triple loop gives excellent strength (120-140%)
Doesn’t compromise the extensor mechanism
Biological graft (immunogenicity)
No weakness of hamstrings
Lipscomb AB, et al. Evaluation of hamstring strength following use of
Semitendinosis and gracilis tendons to reconstruct the anterior cruciate ligament.
Am J Sports Med. 1982;10(6):340-342.
17
No Loss of Hamstring Strength
Lipscomb AB, et al. Evaluation of hamstring strength following use of Semitendinosis and
gracilis tendons to reconstruct the anterior cruciate ligament. Am J Sports Med.
1982;10(6):340-342.
Harter RA, et al. Long-term evaluation of knee stability and function following surgical
reconstruction for anterior cruciate ligament insufficiency. Am J Sports Med 1988;16:434-
443.
Shino K, et al. Quantitative evaluation after arthroscopic anterior cruciate ligament
reconstruction: Allograft versus autograft. Am J Sports Med 1993;21:609-616.
Sachs RA, et al. Patellofemoral problems after anterior cruciate ligament reconstruction. Am
J Sports Med 1989;17:760-765.
Conteduca F, et al. LAD augmentation in ACL reconstructions with pes anserius:
Comparison between proximal and distal detachment. Internal-external forces analysis with
Cybex II evaluation. Presented at the IV European LAD Study Club Meeting, Edinburgh,
Scotland, 1990.
Yasuda K, et al. Graft site morbidity with autogenous semitendinosus and gracilis tendons.
Am J Sports Med 1995;23:706-714.
No Loss of Hamstring Strength
Simonian PT, et al. Assessment of morbidity of semitendinosus and gracilis tendon harvest
for ACL reconstruction. Am J Knee Surg 1997;10:54-59.
Carter TR, Edinger S. Isokinetic evaluation of ACL reconstruction. Hamstring versus patellar
tendon. Arthroscopy 1999;15:169-172.
Nakamura N, et al. Evaluation of Active Knee-Flexion and Hamstring Strength After
Anterior Cruciate Ligament Reconstruction Using Hamstring Tendons. Arthroscopy.
18(6):598-602, 2002.
Semi-T/Gracilis Autograft
Two possible explanations for maintaining
hamstring strength:
Tendons remain functional
Compensatory hypertrophy of undisturbed knee
flexors.
MRI cross sectional areas of biceps femoris,
semimembranosus and sartorius muscles were not
significantly different
Simonian PT, et al. Assessment of Morbidity of Semitendinosus and Gracilis
Tendon Harvest for ACL Reconstruction. Am J Knee Surg. 10(2):54-59;1997.
18
Semi-T/Gracilis Autograft
Distal most insertion of semi-T & Gracillis
tendons after harvest were always more
proximal than the non-op side
Majority of cases demonstrated some but
never complete re-growth or scar formation
of these tendon remnants
Simonian PT, et al. Assessment of Morbidity of Semitendinosus and Gracilis
Tendon Harvest for ACL Reconstruction. Am J Knee Surg. 10(2):54-59;1997.
Semitendinosis/Gracilis Graft
Disadvantages
Limited long-term follow-up studies
Slower rehabilitation
Soft tissue to bone healing
Still requires diligent rehabilitation
Chronic tendonitis of Semimembranosis
Small tendon
Lizard Tail Phenomenon
19
Lizard Tail
Study to evaluate the ability of the native semi -T to
regenerate after harvest for ACL replacement
Rabbit model; All 10 specimens demonstrated regeneration
at 16 and 28 weeks with normal appearing histological and
morphologic characteristics
Biomechanical strength 23% normal at 16 weeks and 62%
normal at 28 weeks
Leis HT, et al. Hamstring Regrowth Following Harvesting for
ACL Reconstruction. J Knee Surg, 2003;16(3):159-164.
Lizard Tail
Patellar tendon harvest site has been shown
to refill with scar tissue
Biomechanically inferior to native patellar
tendon and not suitable for revision ACL
reconstruction
Leis HT, et al. Hamstring Regrowth Following Harvesting for
ACL Reconstruction. J Knee Surg, 2003;16(3):159-164.
Lizard tail in humans
40 patients ; pre-post ultrasonagraphy
Post US @ 2 wks, 1,2,3,6,12,18,24 mo.
2 weeks: site occupied by an area of increased
thickness and decreased echo, suggesting edema
of soft tissue
1 month: irregular hypoechoic structure appeared
in near anatomic position
Papandrea P, et al. Regeneration of the Semiteninosus Tendon
Harvested for Anterior Cruciate Ligament Reconstruction. J
Sports Med, 28(4):556-561, 2000.
20
Lizard tail in humans
2 mo: Thickness, width, and cross-sectional area were significantly greater than pre-operatively
1 yr: Distinct edges and reduction in thickness and width
18 & 24 mo: Echogenicity of structure very similar to that of normal tendon, but approx. 4 cm proximal to pes anserine.
Papandrea P, et al. Regeneration of the Semiteninosus Tendon
Harvested for Anterior Cruciate Ligament Reconstruction. J
Sports Med, 28(4):556-561, 2000.
ACL ALLOGRAFT
Allograft
Indications
Older individual with substantial DJD or
low desire for high impact activities
When short convalescence is important
Accept increased likelihood of graft
failure
21
Allograft
Advantages
Biological graft – cadaveric tissue retrieved
from tissue bank which is capable of
remodeling and repair
Decreased surgical morbidity with endoscopic
placement, no compromise of normal anatomy
May require less intense of rehabilitation
No other options
Allograft
Disadvantages
Transmission of communicable disease
Prolonged remodeling/revascularization time
Expense and availability – graft alone >$2000
Tissue radiation – decreased tensile strength (?)
YUCK effect - GJD
External biological tissue
Greater chance of infection
May create chronic synovitis
Allograft vs Auto in Younger
Systematic review with meta-analysis
Comparative studies of allograft vs autograft in those <25 years of age and high activity level
7 studies – 788 auto; 288 allo
Mean age 21.7 years; follow up time =24-51 months
Wasserstein D, Sheth U, Cabrera A, Spindler KP. A systematic
review of failed ACL reconstruction with autograft compared with
allograft in young patients. Am J Sports Med. 2015;7(3):207-216.
22
Allograft vs Auto in Younger
Pooled failure variance
Autografts = 9.6 (76/788
Allografts = 25% (57/228)
Wasserstein D, Sheth U, Cabrera A, Spindler KP. A systematic
review of failed ACL reconstruction with autograft compared with
allograft in young patients. Am J Sports Med. 2015;7(3):207-216.
Thermal Treatment to Partial
ACL Tears
Thermal energy has been useful in
treatment of shoulder instability for some
time
Recently thermal energy has been used to
treat laxity of the ACL following surgery or
in partially torn ACL’s
BE CAREFUL!
23
Thermal Treatment for ACL’s
A paucity of in vivo, in vitro, and clinical
data are available with regard to this
potential treatment regime.
Lopez and Markel
Monoploar RFE to the normal ACL of one knee in each of 18 dogs with sham treatment of the contralateral ACL.
Results showed rupture of all treated ligaments approximately 55 days after surgery.
Rupture detected by sudden onset of NW status and + drawer sign.
Lopez, MJ, Markel MD. Anterior cruciate ligament rupture after
thermal treatment in a canine model. Am J Sports Med. 2003;
31(2):164-167.
Sekiya JK, Golladay GJ, Wojtys E
Case Study
16 yo female injured L knee playing basketball
ACLR with semi T/Gracilis
5 months after surgery patient re-injured knee.
Arthroscopy revealed irreparable medial meniscus
tear with ACL in continuity but lax
Sekiya JK, et al. Autodigestion of a Hamstring ACL autograft following
thermal shrinkage. J Bone Joint Surg. 82A:1454-1457, 2000.
24
Autodigestion
ACL treated with heat probe 65 degrees C
as recommended by manufacturer
Graft shrinkage was seen. Following
procedure Lachmans revealed no increased
laxity compared to uninvolved side
13 week after 2nd surgery sustained non
contact knee injury
Sekiya JK, et al. Autodigestion of a Hamstring ACL autograft following
thermal shrinkage. J Bone Joint Surg. 82A:1454-1457, 2000.
Autodigestion
PE revealed 3+ Lachman’s with no end point
2 weeks later arthroscopy revealed to remnant of previous hamstring graft identifiable in the notch
Revision with BPTB
9 months following surgery no subjective instability and Lachman’s (-)
Sekiya JK, et al. Autodigestion of a Hamstring ACL autograft following
thermal shrinkage. J Bone Joint Surg. 82A:1454-1457, 2000.
Autodigestion
23 year old male athlete
Hyperextension injury playing semi professional
football
Tx four weeks after injury with RFE
Operative report detailed ligament treated on
anterior aspect with “good visual shrinkage”
Post treatment “looked like a normal ligament
with no laxity”
Bailie DS, Ellenbecker TS. Case illustrates risk of thermal shrinkage
in knee joint. Biomechanics 10(9):2003.
25
Bailie DS, Ellenbecker TS. Case illustrates risk of thermal shrinkage
in knee joint. Biomechanics 10(9):2003.
Bailie DS, Ellenbecker TS. Case illustrates risk of thermal shrinkage
in knee joint. Biomechanics 10(9):2003.
Autodigestion
Braced 3 weeks in full extension
Returned to full activities in 15 weeks
(-) Lachmans, pivot shift and no c/o pain or
instability
6 months later reported to clinic after
sustaining non-contact twisting injury while
playing soccer. Felt “pop” in same knee
Bailie DS, Ellenbecker TS. Case illustrates risk of thermal shrinkage
in knee joint. Biomechanics 10(9):2003.
26
Autodigestion
Minimal swelling and med joint line pain
2+ Lachman’s, 2+ pivot shift and 8mm side
to side difference laxity with KT-1000
MRI revealed non-visualization of ACL
Absence of ACL noted during surgery
Bailie DS, Ellenbecker TS. Case illustrates risk of thermal shrinkage
in knee joint. Biomechanics 10(9):2003.
27
Reasons for Autodigestion
Biomechanical alteration of the collagen
may have led to failure of the graft
An immune-mediated response resulted in
autodigestion of the graft.
Sekiya JK, et al. Autodigestion of a hamstring anterior cruciate
ligament autograft following thermal shrinkage: A case report and
sentinel of concern. J Bone J Surg. 2000;82-A(10):1454-1457.
Thermal Shrinkage – 2 Year FU
64 patients
2 centers
Lax ACL from native
or previous reconstructions
> 2 year follow-up
Smith DB, Carter TR, Johnson DH. High failure rate for electrothermal
shrinkage of lax ACL: Multicenter follow-up past 2 years. Arthroscopy.
2008;24:637-641.
Thermal Shrinkage – 2 Year FU
Failure as determined by 5mm increase in
laxity with KT-1000
Overall 50.8%
Previous reconstructions 78.9%
Native ACLs 38.1%
Smith DB, Carter TR, Johnson DH. High failure rate for electrothermal
shrinkage of lax ACL: Multicenter follow-up past 2 years. Arthroscopy.
2008;24:637-641.
28
Surgical Delay
Relationship between ACL reconstruction
delay and incidence of secondary injury
1434 patients
Time to surgery after initial injury
Ralles S, Agel J, Obermeier M, Tompkins M. Incidence of secondary
intra-articular injuries with time to anterior cruciate ligament
reconstruction. Am J Sports Med. 2015;43(6):1373-1379.
Surgical Delay
Time delay
0-3 months
4-12 months
> 12 months
Association noted between time to surgery and
injury
Trochlea, lat fem condyle, med tib plateau,
medial meniscus
Ralles S, Agel J, Obermeier M, Tompkins M. Incidence of secondary
intra-articular injuries with time to anterior cruciate ligament
reconstruction. Am J Sports Med. 2015;43(6):1373-1379.
Early Revision Predictors
32 adolescents – ACL surgery
Mean age 15.2 years
21(91%) followed at 10-20 years after
Clinical, radiographic and QOL data
Mansson O, Sernert N, Rostgard-Christnesen L, Dartus J. Long-term
clincal and radiographic results after delayed anterior cruciate ligament
reconstruction in adolescents. Am J Sports Med. 2014;43:138-145.
29
Early Revision Predictors
Reconstructed knee significantly more OA
compared with non involved knee
Tegner and Lysholm scores not different pre and
post
Strength and stability improved
Subjective scales varied
Mansson O, Sernert N, Rostgard-Christnesen L, Dartus J. Long-term
clinical and radiographic results after delayed anterior cruciate ligament
reconstruction in adolescents. Am J Sports Med. 2014;43:138-145.
Graft Failure
Categorization of Graft Failure
Error in Surgical Technique
Failure of Incorporation
Trauma
Gries PE, Johnson DL, Fu FH: Revision anterior cruciate ligament surgery: Causes of graft failure and technical considerations of revision surgery. Clin Sports Med. 12;839:1993.
30
Error in Surgical Technique
Initially incompletely recognized or
addressed complex ligament injuries
inadequate notch plasties
Improper tunnel placement
Improper graft tensioning
Insufficient fixation
Failure of Incorporation
Failure of graft to mature and remodel
Trauma
Insufficient or excessive rehabilitation
Recurrent injury (knee abuser)
31
Strain on ACL
Running Downhill 125%
Isometric quad contraction, 22° knee flex, 20-lb 62-121%
Isometric quad contraction, 0° knee flex, 20-lb 87-107%
Jog on floor 89%
Leg lift, 22° knee flexion 12-79%
Jog 5 mph on treadmill 62-64%
Isometric quad contraction, 45° knee flexion, 20-lb 50%
Walk without assist device 36%
Half-squat, one leg 21%
Quad set 18%
Walk with crutches, 50-lb weight bearing 7%
Stationary cycle 7%
Isometric hamstring contraction -7%
Strain on ACL Isometric quadriceps contraction 15° 4.4%
Squatting with resistance 4.0%
Active knee flexion with resistance 3.8%
Lachman’s test (150N anterior shear at 30°) 3.7%
Squatting without resistance 3.6%
Active knee flexion without resistance 2.8%
Quadriceps and hamstring co-contraction at 15° 2.7%
Isometric quadriceps contraction at 30° 2.7%
Stair climbing 2.7%
Anterior drawer test (150 N anterior shear at 90°) 1.8%
Stationary bicycle 1.7%
Quadriceps and hamstrings co-contraction at 30° 0.4%
Passive knee range of motion 0.1%
Isometric quadriceps at 60° and 90° 0.0%
Quad and hamstring co-contraction at 60 ° and 90 ° 0.0%
Isometric hamstring contraction at 30°, 60°, 90° 0.0%
Fleming BC, Beynnon BD, Renstrom PA, et al. The strain behaviouir of the
ACL during stair climbing. An in vivo study. Arthroscopy. 1999;15:185-191.
Ligamentization
Necrosis
Revascularization
Cellular proliferation
Collegen formation
32
Necrosis
First 3 weeks following surgery
Graft needs blood supply
Native cells diminish
Graft nourished by synovial fluid and bone
blood supply
Revascularization
Within first 6-8 weeks
Inflammatory response under control
Bone plugs generally incorporate into
tunnels within 12 weeks
Cell proliferation
Tissue begins to become vascularized
Fibroplasia
Fibroblastic activity collagen and elastin
Tensile strength of ligament slowly
increases
33
Collagen formation (Maturation)
Long-term process
Collagen remodeled in lines of stress
according to tensile forces placed on tissue
Tissue gradually assumes normal
appearance
May require over 1 year
Graft Maturity
Comparison of quad
tendon with bone to
hamstring auto
26 patients
12 quad
14 hamstring
1.5 T MRI .5 years
postoperatively
Ma Y, et al. Graft maturity of the reconstructed anterior cruciate ligament 6 months
postoperatively: a magnetic resonance imaging evaluation of quadriceps tendon with
bone block and hamstring tendon autografts. Knee Surg Sports Traumatol Arthrosc.
2014:DOI:10.1007/s00167-014-3302-0.
Signal to noise ratio
Quad tendon =1.74
Hamstring = 2.44
Rehab may require
modifications
Ma Y, et al. Graft maturity of the reconstructed anterior cruciate ligament 6 months
postoperatively: a magnetic resonance imaging evaluation of quadriceps tendon with
bone block and hamstring tendon autografts. Knee Surg Sports Traumatol Arthrosc.
2014:DOI:10.1007/s00167-014-3302-0.
34
Graft Maturity
Comparison of allo
vers auto
52 patients
30 allografts
22 autografts
3.0 T MRI 2 years
postoperatively
Hong L, Tao H, Cho S, Chen S, Yau Z, Chen S. Difference in graft maturity of the
reconstructed anterior cruciate ligament 2 years postoperatively. Am J Sports Med.
2012;40:1519-1526.
Graft Maturity
Outcomes
Subjective
IKDC
Tegner scores
Physical examination
Lachmans test
Anterior drawer
Hong L, Tao H, Cho S, Chen S, Yau Z, Chen S. Difference in graft maturity of the
reconstructed anterior cruciate ligament 2 years postoperatively. Am J Sports Med.
2012;40:1519-1526.
Graft Maturity
All normal function by 2 years
No subjective score difference
No difference in laxity measures
Signal/noise quotient allograft significantly higher
than autograft
Indicating inferior graft maturity
Hong L, Tao H, Cho S, Chen S, Yau Z, Chen S. Difference in graft maturity of the
reconstructed anterior cruciate ligament 2 years postoperatively. Am J Sports Med.
2012;40:1519-1526.
35
Structured Rehab with Surgery
Vs. Structured Rehab and option for surgery
121 young active
adults – acute ACL
tear
Rehab + ACL
repair
Rehab and option
for repair
Frobell RB, et al. A randomized trial of treatment for acute anterior
cruciate ligament tears. N Engl J Med 2010;364(4):331-342.
Structured Rehab with Surgery
Vs.
Structured Rehab and option for surgery
2 year follow-up
Change in outcome scales
4 subscales of KOOS
Short Form 36 Survey
Tegner Activity Scale
Frobell RB, et al. A randomized trial of treatment for acute anterior
cruciate ligament tears. N Engl J Med 2010;364(4):331-342.
Structured Rehab with Surgery
Vs.
Structured Rehab and option for surgery
Both groups saw improvements
No significant change between two groups
in either primary or secondary outcomes
Early structured rehabilitation with surgery
did not attain better outcomes than
structured rehabilitation
Frobell RB, et al. A randomized trial of treatment for acute anterior
cruciate ligament tears. N Engl J Med 2010;364(4):331-342.
36
Editorial: Arthroscopy
Apples vs. Apples + Oranges
39% of delayed group went ahead to have
surgery
100% of surgery group had surgery, but so
did 39% of conservative
Tegner scores were significantly different
Tegner better at measuring higher demand
activities than KOOS
Richmond JC, Lubowitz JH, Poehling GG. Prompt operative
intervention reduces long-term osteoarthritis after knee anterior
cruciate ligament tear. Arthroscopy. 2011;27(2):149-152
Editorial: Arthroscopy
Surgical group returned to cutting activities
Non surgical group limited to jogging
Surgery group 39 of 60 (65%) sustained
meniscal damage at time of injury, but only
29 (48%) ended up with resections
Delayed surgery group 30 of 59 (51%)
sustained meniscal tears at time of injury,
but in end 41 of 59 (70%) required resection
Richmond JC, Lubowitz JH, Poehling GG. Prompt operative
intervention reduces long-term osteoarthritis after knee anterior
cruciate ligament tear. Arthroscopy. 2011;27(2):149-152
General ACL Rehabilitation
37
Discussion Today
Single-Bundle ACL
Reconstruction
Discussion Tomorrow
Double-Bundle ACL
Reconstruction
Single-Bundle Technique
Used since 1970’s
Geometry of ACL very
complex
Single-bundle technique
does not duplicate normal
anatomy?
Beynnon BD, et al. Treatment of anterior cruciate ligament injuries:
Part 1. Am J Sports Med 2005;33:1579-1602.
Beynnon BD, et al. Treatment of anterior cruciate ligament injuries:
Part 2. Am J Sports Med 2005;33:1751-1767.
38
Single-Bundle Technique
High level of OA following ACL
reconstructions.
Single-bundle unable to control valgus and
internal rotation force (Pivot Shift)
Woo SL, et al. The effectiveness of reconstruction of the anterior
cruciate ligament with hamstrings and patellar tendon: a cadaveric
study comparing anterior tibial and rotational loads. J Bone Joint
Surg 2002;84A:907-914.
Knee OA following
ACL reconstruction
prevalence rates in
studies may be too
high
Methodological
quality of studies low
Oiestad BE, et al. Knee OA after anterior cruciate ligament injury. A
systematic review. Am J Sports Med 2009;37(7):1434-1443.
Highest rated studies
report OA range of 0-
13% for those with
isolated ACL injury
OA ranges of 21-48%
with combined injuries
Oiestad BE, et al. Knee OA after anterior cruciate ligament injury. A
systematic review. Am J Sports Med 2009;37(7):1434-1443.
39
Single-Bundle Technique
2007 review
124 papers on double bundle
120 since 2000
Crawford C, Nyland J, Landes S, et al. Anatomic double-bundle ACL
reconstruction: a literature review. Knee Surg Sports Traumatol
Arthrosc 2007;15: 946-964.
Meta-Analysis
Double-bundle restores KT-1000 outcomes
0.52 mm closer than single-bundle (Sig)
Odds of normal pivot shift is higher in
Double-bundle than those in single-bundle
but – (Not Sig).
Meredick RB, et al. Outcomes of single-bundle versus double-bundle
reconstruction of the anterior cruciate ligament. A meta-analysis. Am
J Sports Med 2008;36:1414-1421.
http://www.docjago.com/uch/multiple_instab-Dateien/image004.jpg
40
Single-bundle Double-bundle
www.ceo-ortopedia.com.br/eventos.htm
Single-
bundle
Kondo E, et al. Prospective clinical comparisons of anatomic double-bundle
versus single-bundle anterior cruciate ligament reconstruction procedures in 328
consecutive patients. Am J Sports Med. 2008;36:1675-1687.
ACL Rehabilitation
41
Randomized
controlled trial
Formal PT
(17 sessions)
Home based
(4 sessions)
88/129 patients
returned at 2 or 4
years
Grant JA, Mohtadi NGH. Two- to 4 – year follow-up to a comparison of home versus
physical therapy – supervised rehabilitation programs after anterior cruciate ligament
reconstruction. Am J Sports Med 2010;38(7):1389-1394.
Outcomes
ACL QOL score
Knee ROM
Knee laxity
IKDC scores
Home based group had
higher mean ACL QOL
scores 38 weeks after
surgery
Both groups improved from
pre-post
Grant JA, Mohtadi NGH. Two- to 4 – year follow-up to a comparison of home versus
physical therapy – supervised rehabilitation programs after anterior cruciate ligament
reconstruction. Am J Sports Med 2010;38(7):1389-1394.
Systematic review
Level 1 & 2
54 appropriate
studies
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
42
CPM Following ACL
6 studies all had some limitations
Potentially caused type II error
No advantage for CPM use
Except for possible decrease in pain
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
Early Weight Bearing
1 RCT discussed later
Early weight bearing probably justified
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
Post Operative Bracing
11 studies
No study demonstrated worse outcomes
when bracing was not used
No increase in postop injuries, increased
pain, decreased motion, or increased knee
laxity in controls
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
43
Home-Based Rehab
4 RCTs
All have some potential bias!
Despite this it is reasonable to conclude
that a minimally supervised physical
therapy –based program can result in
successful ACL rehabilitation
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
Systematic review
Level 1 & 2
54 appropriate
studies
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part II: Open versus closed kinetic chain exercises, neuromuscular electrical
stimulation, accelerated rehabilitation, and misc topics. J Knee Surg 2008;21:225-234.
OKC vs CKC
5 RCTs
All have some potential bias!
All short term outcomes (6 weeks)
3 demonstrate lack of power
Need for additional study
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
44
Neuromuscular Electrical Stim
14 RCTs
For NM ESTM to be successful it must be
applied at high intensity
May help achieve quad strength
But is not a requirement
Wright RW, et al. A systematic review of anterior cruciate ligament reconstruction
rehabilitation. Part I: Continuous passive motion, early weight bearing, postoperative
bracing, and home based rehabilitation. J Knee Surg 2008;21:217-224.
CPM
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
No long term
benefit
No increased ROM
Insurance not
always approve so
cost issue
Early Weight Bearing
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
No new studies
45
Postoperative Bracing
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
6 new studies since
2005
None demonstrated
advantage from
bracing
OCK vs CKC
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
OKC activity after
6 weeks may
increase strength
without harming
graft
Not sufficient
evidence for OKC
prior to 6 weeks
NMES
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
No new studies
Some home units
may not be strong
enough to elicit
contraction
46
Accelerated Rehabilitation
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
2 new studies since
2005
Most return at 6
months
Unknown if shorter
time frames
harmful
Neuromuscular Training
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
9 new studies since
2005
Most have shown
efficacy
Recommended
some form of
training be included
Home Based Therapy
Wright RW, et al. Anterior Cruciate Ligament Reconstruction Rehabilitation: MOON
Guidelines. Sports Health. 2015;7(3):239-243.
2 new studies since
2005
Biases and
limitations
Have not been
shown to be
deleterious
47
74 patients – RCT
Neuromuscular program
Strengthening program
Follow-up
6 months
1 year
2 years
Outcomes
Cincinnati knee score
VAS pain; short form 36
Functional tests; strength
Risberg MA, Holm I. The long-term effect of 2 postoperative rehabilitation programs after
anterior cruciate ligament reconstruction. RCT with 2 years follow-up. Am J Sports Med
2009;37(10:1958-1966.
No significant differences between programs at 1 and 2
years for Cincinnati knee scale
At 2 years
NE group significantly improved function and
reduced pain
SE group significantly improved hamstring strength
Both SE and NE type of exercises should be used
following ACL reconstruction
Risberg MA, Holm I. The long-term effect of 2 postoperative rehabilitation programs after
anterior cruciate ligament reconstruction. RCT with 2 years follow-up. Am J Sports Med
2009;37(10:1958-1966.
Postoperative
1-2 decades ago knee placed in 20-30
degrees of flexion for 6-8 weeks with
restricted weight bearing
Recent advances in surgical technique and
understanding of tissue healing have
allowed early p/o ROM and immediate
weight bearing
48
Past vs. Present
PAST PRESENT
Prolonged
Immobilization
Immediate Motion
Non-Weight Bearing Early Weight Bearing
Slow Progression of
Activity
Accelerated Return to
Activity
Immobilization
Generally knee placed in controlled motion brace locked in extension or between 20-0 degrees of flexion
Correct isometric placement allows full ROM without disrupting the autograft
If procedure combined with collateral ligament repair or meniscus repair, ROM may be restricted
Immobilization
Knee is kept immobilized during
ambulation and at night, but removed for
supervised exercises
49
Cryotherapy
Patients utilizing continuous cryotherapy
Required less medication
Converted from injectable to oral meds
sooner
Greater percentage of compliant patients
Cohn BT, et al. The effects of cold therapy in the postoperative
management of pain in patients undergoing anterior cruciate ligament
reconstruction. Am J Sports Med 1989;17:344-349.
Cryotherapy
Patients utilizing continuous cryotherapy
Were out of bed and ambulating sooner
Performed ROM exercises with more
ease.
Cohn BT, et al. The effects of cold therapy in the postoperative
management of pain in patients undergoing anterior cruciate ligament
reconstruction. Am J Sports Med 1989;17:344-349.
Raynor MC, et al. Crotherapy after ACL reconstruction. A meta-
analysis. J Knee Surg. 2005;18:123-129.
Knee Effusion 53 year old male following
bilateral patellar tendon rupture
repair after fall.
Used cryocuff device for 2
weeks straight.
Returned at 4 weeks with
eschars of both knees
Then debridement, dressing
change and wound coverage
Lee CK, et al. Sever frostbite of knees after cryotherapy. Orthopedics.
2007;30:
http://www.healio.com/orthopedics/journals/ORTHO/%7B8F4A824C-BAD6-
4708-8242-DC8B11857CCA%7D/Severe-Frostbite-of-the-Knees-After-
Cryotherapy?full=1
50
Knee Effusion
4 weeks after free tissue skin
graft transplant
Lee CK, et al. Sever frostbite of knees after cryotherapy. Orthopedics.
2007;30:
http://www.healio.com/orthopedics/journals/ORTHO/%7B8F4A824C-BAD6-
4708-8242-DC8B11857CCA%7D/Severe-Frostbite-of-the-Knees-After-
Cryotherapy?full=1
Knee Effusion
188 patients; single surgeon
Effusion, ROM, instability,
MVIC and activation level.
Effusion grade did not correlate
with quadriceps central
activation ratio
People may adapt to effusion?
Experimentally induced
effusion may be different than
natural effusion
Lynch AD, Logerstedt DS, Axe MJ, Snyder-Mackler L.Quadriceps activation
failure after anterior cruciate ligament rupture is not mediated by knee joint
effusion. J Orthop Sports Phys Ther. 2012;42:502-510.
Rate of Exercise Progression
Depend on surgical procedure and graft selection
Can progress most rapidly with bone-tendon -bone
repairs or allograft repairs with bone plugs due to
better fixation
Open procedures, or procedures using semi-T,
Gracilis, quad tendon or iliotibial band may
require slower progression due to soft tissue
fixation
51
Rate of Exercise Progression
Even though early movement will create a
stronger better oriented scar and ligament
healing, too much stress or too rapid
progression can stretch or damage repairs
Graft Strength
Animal studies indicate that graft strength
may reach weakest point at 6-8 weeks
postoperatively
Butler DL, et al. Mechanical properties of primate vascularized vs. non-
vascularized patellar tendon grafts: change over time. J Orthop Res
1989;7:68-79.
Graft Strength
Graft may only reach failure loads of 11 and
50% of native ACL at 1-year post operative.
Ballock RT, et al. Use of patellar tendon autograft for anterior cruciate
ligament reconstruction in the rabbit: a long-term histologic and
biomechanical study. J Orthop Res 1989;7:474-485.
52
Graft Strength
Most studies done on animal models
Makes determining optimal load and
optimal timing of load in humans difficult
to determine.
Beynnon BD, et al. The science of anterior cruciate ligament rehabilitation.
Clin Orthop 2002;9-20.
Primary Goal of ACL
Reconstruction
Restoration of knee stability
Safe and expedient return to normal
activities and athletics
Early recognition of complications
Maximum Protection Phase
0-6 weeks: Goals
Protect graft fixation
Minimize effects of immobilization
Control swelling and inflammation
Achieve full extension ASAP
Educate patient on rehab
53
Brace
Dependent on fixation.
Generally:
0-1 week: locked in full extension for ambulation and sleeping
May be longer with soft tissue healing, e.g., hamstring, quad tendon
1-4 weeks: Unlocked for ambulation, sleeping
Weight Bearing
Generally:
0-4 weeks: weight bearing as tolerated
Emphasis on achieving full knee extension
at heel strike with FWB on involved side
Decrease ambulation with flexed knee
Wean off crutches when good quad control
and able to perform SLR with no lag
54
Bone Mineral Density - ACL
BMD and BMC
15 Subjects
Ages 17-51 Years
Time from surgery 6 to 32 months
BMD < in involved lower extremity
Reiman MP, Rogers ME, Manske RC. Interlimb differences in lower
extremity bone mineral density following ACLR. J Orthop Sports Phys
Ther 2006;36(11):837-844.
Bone Mineral Density - ACL
6.6% < at trochanteric region
4.0% < for entire hip
3.4% < for intertrochanteric region
Reiman MP, Rogers ME, Manske RC. Interlimb differences in lower
extremity bone mineral density following ACLR. J Orthop Sports Phys
Ther 2006;36(11):837-844.
Weight Bearing
24 patients per group
Controls
6-12 weeks
6-7 months
12-15 months
Neitzel HA, Kernozek TW, Davies GJ. Loading response following
ACL reconstruction during parallel squat exercise. Clin Biomech.
2002;17:551-554.
55
Weight Bearing
Smith squat rack
Pedar sensors
3 sets of 9 squats
randomized
3 angles (30,60,90°)
3 weights (40# bar only, 35% BW, 50%
BW)
Neitzel HA, Kernozek TW, Davies GJ. Loading response following ACL
reconstruction during parallel squat exercise. Clin Biomech. 2002;17:551-
554.
Weight Bearing
Do you feel like
equal weight placed through both feet?
Significant differences (p<0.05) between
with group interaction with weight and
angle
Neitzel HA, Kernozek TW, Davies GJ. Loading response following
ACL reconstruction during parallel squat exercise. Clin Biomech.
2002;17:551-554.
Weight Bearing
6-12 weeks
Unconscioulsy “Unload LE”
6-7 months
Unconsciously “Unload LE”
12-14 months
Do not “Unload”
Neitzel HA, Kernozek TW, Davies GJ. Loading response following
ACL reconstruction during parallel squat exercise. Clin Biomech.
2002;17:551-554.
56
Weight Bearing
Most patients thought they had
demonstrated equal WB
? Accelerated rehabilitation program
Full sports at 6 months after surgery
Benefit of early single-leg exercise
Neitzel HA, Kernozek TW, Davies GJ. Loading response following
ACL reconstruction during parallel squat exercise. Clin Biomech.
2002;17:551-554.
Weight Bearing
RCT with 49 patients
Immediate weight bearing vs delayed
weight bearing x 2 weeks
BPTB ACL reconstruction
Follow up 2 weeks and final
Tyler T, et al. The effect of immediate weight bearing after anterior
cruciate ligament reconstruction. Clin Orthop 1998;357:141-148.
Weight Bearing
ROM – NS at 2 weeks or final (6-14 mo)
VMO EMG activity significant increase at
2 weeks in weight bearing group
Final follow up both groups EMG same
Tyler T, et al. The effect of immediate weight bearing after anterior
cruciate ligament reconstruction. Clin Orthop 1998;357:141-148.
57
Weight Bearing
Statistically significant decrease in
anterior knee pain
Pain in 7/20 restricted WB
Pain in 2/25 immediate WB
ROM and KT scores not sig different
between groups
Tyler T, et al. The effect of immediate weight bearing after anterior
cruciate ligament reconstruction. Clin Orthop 1998;357:141-148.
Maximum Protection Phase
0-6 weeks Control of postoperative
pain, and edema: use cryotherapy, e-stim, elevation and compression
Caution if using Cryocuff and Tube-grip together – may compromise vascular flow
Mindrebo N, Shelbourne KD. Knee pressure dressings and their effect
on lower extremity venous capacitance and venous outflow. Orthop Int
1994;2:273.
Maximum Protection Phase
0-6 weeks Begin setting exercises
and muscle stimulation to prevent atrophy
Due to closed packed position, little stress placed on graft in full knee extension
58
Quadriceps Atrophy
Atrophy and weakness of quadriceps can
begin immediately following ACL repair
and is the major group that undergoes
atrophic changes.
Sachs R, et al. Patellofemoral problems after ACL reconstruction. Am J Sports
Med 1989;17:760-7655.
Gerber C, et al. The lower extremity musculature in chronic symptomatic
instability of the ACL. J Bone Joint Surg 1985, 67A:1034-1043.
Quad Atrophy
Like to see forceful quadriceps contraction within the 4th post-operative day
If unable to initiate we will begin neuromuscular electrical stimulation to facilitate a contraction
Electrical Stimulation of ThighArvidssoon I, et al. Prevention of quadriceps wasting after immobilization:
an evaluation of the effect of electrical stimulation. Orthopedics.
1986;9:1519-1528.
Delitto A, et al. Electrical stimulation versus voluntary exercise in
strengthening thigh musculature after anterior cruciate ligament surgery.
Phys Ther 1988;68:660-663.
Fitzgerald GK, et al. A modified neuromuscular electrical stimulation
protocol for quadriceps strength training following anterior cruciate ligament
reconstruction. J Orthop Sports Phys Ther 2003;33:492-501.
Lieber RL, et al. Equal effectiveness of electrical and volitional strength
training for quadriceps femoris muscles after anterior cruciate ligament
surgery. J Orthop Res 1996;14:131-138.
Paternostro-Sluga T, et al. Neuromuscular electrical stimulation after
anterior cruciate ligament surgery. Clin Orthop 1999;368:166-175.
59
Electrical Stimulation of ThighRebai H, et al. Effects of two electrical stimulation frequencies in thigh muscles after
knee surgery. Int J Sports Med 2002;23:604-609.
Ross M, The effect of neuromuscular electrical stimulation during closed kinetic chain
exercise on lower extremity performance following anterior cruciate ligament
reconstruction. Sports Med Train Rehabil 2000;9:239-251.
Sisk TD, et al. Effect of electrical stimulation on quadriceps strength after reconstructive
surgery of the anterior cruciate ligament. Am J Sports Med 1987;15:215-220.
Snyder-Mackler L, et al. Electrical stimulation of the thigh muscles after reconstruction
of the anterior cruciate ligament. J Bone Joint Surg 1991;73A:1025-1035.
Snyder-Mackler et al. Strength of quadriceps femoris muscle recovery after
reconstruction of the anterior cruciate ligament. J Bone Joint Surg 1995; 77A:1166-1173.
Wigerstad-Lossing I, et al. Effects of electrical muscle stimulation combined with
voluntary contractions after knee ligament surgery. Med Sci Sports Exerc 1988;20:93-98.
Range of Motion
Regain full extension ASAP!
What is normal motion?
Both men and women have hyper-
extension
Men = 5° while Women = 6°
DeCarlo M, Sell K.E. Normative data for range of motion and single-leg hop
in high school athletes. J Sport Rehabil 1997;6:246-255.
60
502 patients
14.1 years PO
Regression analysis
Most important factor
in subjective scores
Knee motion
Shelbourne KD, Gray T. Minimum 10- year results after anterior cruciate
ligament reconstruction. How the loss of normal knee motion compounds
other factors related to the development of OA after surgery. Am J Sports Med
2009;37(3):471-480.
Shelbourne KD, Gray T. Minimum 10- year results after anterior cruciate ligament
reconstruction. How the loss of normal knee motion compounds other factors related
to the development of OA after surgery. Am J Sports Med 2009;37(3):471-480.
98% of patients with normal motion,
normal articular cartilage and intact
menisci had normal radiographs
Even a 3-5° loss of extension motion
compared to opposite knee affected
outcomes
Shelbourne KD, Gray T. Minimum 10- year results after anterior cruciate
ligament reconstruction. How the loss of normal knee motion compounds
other factors related to the development of OA after surgery. Am J Sports Med
2009;37(3):471-480.
61
Study to determine factors related to
motion loss after ACL reconst.
217 consecutive patients
ROM recorded at:
Day of surgery
6 weeks
3 months
Quelard B, et al. Preoperative factors correlating with prolonged range of motion
deficit after anterior cruciate ligament reconstruction. Am J Sports Med
2010;38(10):2034-2039.
Significant correlations
with motion loss and:
Pre-op ROM
Lat comp bone
contusion
Operative delay < 45
days
Female sex
Quelard B, et al. Preoperative factors correlating with prolonged range of motion
deficit after anterior cruciate ligament reconstruction. Am J Sports Med
2010;38(10):2034-2039.
Maximum Protection Phase
Regain full extension ASAP
Passive knee extension with heel block,
prone knee hangs
62
Maximum Protection Phase
Immediate motion to decrease risk of
complications related to loss of motion
Complication rates range from 9-74%
Noyes FR, et al. Early knee motion after open and arthroscopic
anterior cruciate ligament reconstruction. Am J Sports Med
1984;15:149-160.
Dodds JA, et al. Results of knee manipulation after anterior cruciate
ligament reconstruction Am J Sports Med 1991; 19:283-287.
Graf B, Uhr F. Complications of intra-articular anterior cruciate
reconstruction Clin Sports Med 1988;7:835.
Wojtys EM, et al. Patella baja syndrome. Presented at the annual
meeting of the AAOS. New Orleans, LA, 1986.
Cyclops lesion 15-year old
Hamstring ACL 16 weeks PO
Maximum Protection Phase
Knee “Thunks”
Knee is bent slightly and gently allowed to
“thunk” down into extension
May be hard for patient to understand or
tolerate so may want to do on uninvolved
side first
Shelbourne KD, et al. Rehabilitation after anterior cruciate ligament
reconstruction with a contralateral patellar tendon graft: Philosophy, protocol,
and addressing problems. In: Manske RC (ed). Post Surgical Sports
Orthopedic Rehabilitation: Knee and Shoulder, Mosby, 2006.
63
Maximum Protection Phase
Flexion will generally return in time.
Maximum Protection Phase
If hamstring repair may hold active heel
slides for up to 3 weeks.
Some allograft procedures require lifting of
pes – hold active hamstring contraction x 3
weeks
Maximum Protection Phase
Generous patellar mobilizations to decrease risk of
IPCS, arthrofibrosis, knee flexion contracture
Wall slides and heel slides to increase knee flexion
64
Maximum Protection Phase
Precaution:
By 4-6 weeks bone plugs should be adequately healed
Suppose 8-12 weeks before soft tissue healed into tunnels with hamstrings
At 4-6 weeks the graft itself is at its weakest point in the rehab process
West RV, Harner CD. Graft selection in anterior cruciate ligament
reconstruction. J Am Acad Orthop Surg 2005;13(3): 197-207.
Maximum Protection Phase
Stretching
If hamstring may hold
stretching of gastroc
and hamstrings for up
to 3-4 weeks
Maximum Protection Phase
4-6 weeks graft weak and actually necrotic
Avoid resisted OCK activities in the range
of 30-0 degrees of flexion
65
Maximum Protection Phase
Total Leg Strength
(TLS)
SLR x 4
Multi-hip
Moderate Protection Phase
6-12 weeks
Normalize gait
Maintain full extension
Protect fixation
Full flexion ROM
Improve strength, endurance, and
proprioception of lower extremity
Moderate Protection Phase
6-12 weeks This phase is characterized by exercises utilized to
increase strength and ROM
Muscles require increased intensity to allow adaptation for sport-specific demands
By 9-12 weeks graft is becoming more vascularized
Progressive exercises to work on strengthening not only quads and hams, but TLS should be emphasized
120º of knee flexion and extension should easily be obtained during this time frame
66
Moderate Protection Phase
6-12 weeks Precaution:
Avoid CKC exercises
between 60-90º of
knee flexion (PF) and
OKC between 30-0º of
knee flexion as
anterior tibial
translation may stretch
graft?
Minimal Protection Phase
12-24 weeks OKC isotonic exercise
from 90 - 45° safe
Advanced CKC exercises
Single leg squats
Leg press 0 - 45°
Step-up progression
Balance and proprioception
Minimal Protection Phase
12-24 weeks
Bilateral squats level
ground
Progress with
weighted balls or
dumb bells
67
Minimal Protection Phase
12-24 weeks Advanced CKC
exercises
Squats on labile
surface
Watch for proper
form!
Balance and
proprioception
Minimal Protection Phase
12-24 weeks
Advanced CKC
exercises
Balance and
proprioception
Minimal Protection Phase
12-24 weeks Advanced CKC
exercises
Balance and
proprioception
68
Minimal Protection Phase
12-24 weeks Single-leg exercises important
Athletes in competition spend
tremendous amounts of time in
a single-leg position
Single-leg landing training
Minimal Protection Phase
12-24 weeks
Single-leg landing
training
Good Landings!
Minimal Protection Phase
12-24 weeks
Single-leg landing
training
Poor Landings!
Be careful of
excessive rotation in
the transverse plane
upon landing.
69
Minimal Protection Phase
12-24 weeks Lunges
Lunge onto labile
surface
Lunge with
perturbation
Sports specific tasks
Minimal Protection Phase
12-24 weeks
Emphasis placed on light functional
activities such as jogging, stepping,
footwork and agility drills
These activities can be initiated if strength
assessment reveals 75-80% of uninvolved
side and arthrometer reveals stable graft
Minimal Protection Phase
12-24 weeks Plyometrics and
velocity spectrum
isokinetics can be
begun
By 6 months most
return to full pre-
injury activity level
70
Return to Sport Phase 6-9
Months
Goals
Progress:
Strength
Power
Proprioception
Return to Sport Phase 6-9
Months Continue
strengthening and
flexibility as previous
Walk/jog progression
Forward/backward
running
Cutting/crossover
Sports specific drills
Return to Sport Phase 6-9 Months
Double leg squat on BOSU
Labile surface
71
Return to Sport Phase 6-9
Months Plyometrics
Double leg jumps
Labile surface
Return to Sport Phase 6-9
Months Plyometrics
Single leg jumps
Labile surface
72
Deficits in Quad Strength
Literature review
Side to side strength differences
6 months =23% (3-40%)
12 months = 14% (3-28%)
Self reported function deficits
6 months = 14%
12 months = 13%
Hop tests
6 months = 11%
12 months = 1.3%
Lepley LK. Deficits in quadriceps strength and patient-oriented
outcomes at return to activity after ACL reconstruction: A review of
the current literature. Sports Health. 2015;7(3):231-238.
Survival of Graft
All patients – one
surgeon 1993-1994
Telephone or email
Minimum 15 years
after surgery
Bourke HE, et al. Survivial of the anterior cruciate ligament graft and
the contralateral ACL at a minimum of 15 years. Am J Sports Med.
2012;40:1985-1992.
Survival of Graft
775 patients met criteria
BPTB = 314; Ham = 359
673 (89%) responded
23% had suffered graft rupture or contralateral
ACL tear
Graft survival not different between groups
Ham = 88%; BPTB 91%
Bourke HE, et al. Survival of the anterior cruciate ligament graft and
the contralateral ACL at a minimum of 15 years. Am J Sports Med.
2012;40:1985-1992.
73
Survival of Graft
Contralateral rupture 2x as frequent as graft
rupture in BPTB group
Positive family history of ACL injury doubled
odds of having injury to graft or contralateral
ACL
Men less favorable survival rate of graft than
women.
Bourke HE, et al. Survival of the anterior cruciate ligament graft and
the contralateral ACL at a minimum of 15 years. Am J Sports Med.
2012;40:1985-1992.
Smoking and ACL Reconstruction
ACL reconstruction in patients who use tobacco
associated with increased rates of
Infection
VTE
Subsequent ACL reconstruction
Cancienne JM, et al. Tobacco use is associated with increased
complications after anterior cruciate ligament reconstruction. Am J
Sports Med. 2016;44(1):99-104.
Smoking and ACL Reconstruction
66 smokers – FU 5.67 years
238 non-smokers – FU 6.61 years
Similar in age, gender, graft type, fixation
and associated meniscal and chondral
pathology
Karim A, et al. Smoking and reconstruction of the anterior cruciate
ligament. J Bone Joint Surg 2006;88B:1027-1031.
74
Smoking and ACL Reconstruction
Assessment
IKDC scores
Cruciometer
readings
Karim A, et al. Smoking and reconstruction of the anterior cruciate
ligament. J Bone Joint Surg 2006;88B:1027-1031.
Smoking and ACL Reconstruction
SS Poor outcomes in
smokers
IKDC scores
Frequency of pain
Intensity of pain
Laxity
Karim A, et al. Smoking and reconstruction of the anterior cruciate
ligament. J Bone Joint Surg 2006;88B:1027-1031.
Smoking and ACL Reconstruction
Less likely to return to their original level of
pre-injury sport
Well-known negative effects of smoking on
tissue healing affects ACL reconstruction
patients also!
Karim A, et al. Smoking and reconstruction of the anterior cruciate
ligament. J Bone Joint Surg 2006;88B:1027-1031.
75
Smoking and ACL Reconstruction
14 studies
8 smoking and
ligaments
6 smoking and articular
cartilage
Negative association of
smoking
Kanneganti P, et al. The effect of smoking on ligament and cartilage
surgery in the knee. A systematic review. Am J Sports Med.
2012;40:2872-2878.
Smoking and ACL Reconstruction
Negative effects from
various perspectives
Molecularly
Biomechanically
Clinically
Kanneganti P, et al. The effect of smoking on ligament and cartilage
surgery in the knee. A systematic review. Am J Sports Med.
2012;40:2872-2878.