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Antenatal Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology Dr BLK Superspeciality Hospital, New Delhi

Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

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Page 1: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Antenatal Hydronephrosis(ANH):

Surgical Aspects

Dr Prashant Jain Sr. Consultant

Pediatric Surgery & Pediatric Urology

Dr BLK Superspeciality Hospital, New Delhi

Page 2: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Antenatal Hydronephrosis

Renal anomalies accounts for 17% of all the

congenital anomalies

Hydronephrosis is commonest

(1-5% of all pregnancies)

Management dilemma

Page 3: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

ANTENATAL HYDRONEPHROSIS DILATATION OF FETAL RENAL COLLECTING SYSTEM

Transient dilatation

(41 to 88%)

Vesico-ureteric reflux

(10 -20%)

True Obstruction

(20 -50%)

Page 4: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

What is True Obstruction???

• Anatomical or Functional impairment in urinary

drainage from kidney which ultimately is going to

affect the renal function

Impairment in Urinary drainage

Dilatation

Impairment of renal functions

Page 5: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

True obstruction

Pelvi Ureteric Junction

Uretero-vesical Junction

Bladder outlet Posterior Urethral Valve

Page 6: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Why diagnostic Dilemma?

Transient impairment of urinary flow

Permanent impairment of urinary flow

IMPORTANT TO DIFFERENTIATE

Page 7: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Evaluation Of ANH

- Ultrasound

- Micturiting Cystourethrogram

- Nuclear renal scan

* DRCG

* DMSA

* DTPA

- Magnetic Resonance Urography (MRU)

Page 8: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Antero-Posterior Diameter of

Renal Pelvis (Transverse plane)

Page 9: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Definition of ANH by AP(Antero-Posterior) Diameter

of Renal Pelvis

Mild 4 to <7 mm 7 to <9 mm

Moderate 7 to 10 mm 9 to 15 mm

Severe >10 mm >15 mm

Second trimester Third trimester

Page 10: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Case: Antenatal hydronephrosis

Antenatal scan- 32 wks

Lt hydronephrosis with dilated pelvicalyceal system; No

hydroureter

Antero-posterior(AP) diameter of Lt renal pelvis: 13 mm

AFI: 9

What Next??

13mm

Page 11: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Counseling is Challenge…..

Is it a transient dilatation or pathological

dilatation?

What is accurate diagnostic tool?

How to prognosticate?

How long to follow?

When to operate?

Page 12: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis
Page 13: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Risk Of Postnatal Pathology

Mild: 11.8%

Moderate:44.1%

Severe: 88.3%

Page 14: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Moderate hydronephrosis (Resolution: 40-

50%)

CAN NOT BE IGNORED

Re-assessment after delivery

Will require regular follow up with USG and

renal scans

Continue pregnancy till term

Page 15: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Post natal

Newborn passing urine

Bladder not palpable

USG KUB after 48-72hrs

AP Diam: 14mm

What Next?

Chemoprophylaxis

USG & DTPA Scan after 1 month of age

What Next?

Page 16: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

ANTENATAL HYDRONEPHROSIS

Post Natal USG at 48 -72 hrs

No hydronephrosis

Repeat USG at 3 months

No hydronephrosis No further evaluation

Hydronephrosis present Hydro-ureteronephrosis present

Chemoprophylaxis Early MCU

Mild Moderate/severe

Chemoprophylaxis ??MCU DTPA Scan

USG at 3, 6, 12 mths

B/L HN, BLADDER OUTLET OBSTRUCTION, AND SINGLE KIDNEY NEEDS EARLY EVALUATION

Page 17: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Consider Surgery

Split function is < 40%

Progressive increase in AP diameter

Symptomatic

Page 18: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

RK AP DIAMETER LK AP DIAMETER

ANTENATAL - 14 MM

DAY3 - 14 MM

1MTH - 18 MM

3MTH - 18 MM

6MTH 19

12MTH 19

DTPA scan

Advised DTPA scan

Page 19: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

At 2 months of age

Page 20: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

At 1 year of age

Page 21: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Pyeloplasty

Page 22: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Case: Antenatal Hydronephrosis

20 wks scan

28 wks scan

36 wks scan

Before discharge

Rt AP of Pelvis diameter of 6

mm

Rt AP diameter of pelvis 8 mm

Rt AP of Pelvis diameter of 8 mm

Rt AP diameter of pelvis 7mm

USG at 1mth Rt AP of Pelvis diameter of 8 mm

USG at 3mth & 1 year No dilatation

Page 23: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Antenatal Scan 32 wks

Bilateral hydronephrosis and hydroureter

Bilateral AP diameter 7mm

Bilateral echogenic kidneys

Bladder full; Key hole sign

AFI 8

Page 24: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

• POSSIBILITIES????

Page 25: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Antenatal Scan:

Hydrouretronephrosis

Vesico-ureteric reflux

Vesico-ureteric junction obstruction

Posterior Urethral Valve

Page 26: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Counseling

Obstruction at vesico-urethral junction

Need for surgery(Endoscopic

Fulgaration)

Need for long term follow up

Risk of ESRD

Page 27: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Case…

37 wks, LSCS, 1.6 kg

USG: B/L HN & HU

Thinned out renal parenchyma

Thickened and distended bladder

Catheterised

Serum Na: 132

Serum K: 5.3

S. Creatinine:1.6

VBG: Normal

Urine C/S: sterile

Page 28: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

MCU

Page 29: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Endoscopic Fulgaration of Valves

Page 30: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Post Operataive

Stable

Polyuria: 5ml/kg/hr(Post operative diuresis)

Catheter removed after 72 hrs

Polyuria Settled in 7 days

Discharged with S.Creatinine of 1meq/l

Chemoprophylaxis

Anticholinergics (Tropan)

Page 31: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Follow up

Intermittent dribbling present

Urinary Stream good

DMSA: left scarred kidney

S.Creatinine : 0.6

Dilatation on USG is less, PVR5 ml

Now 2yrs

No chemoprophylaxis

Needs long term follow up

MCU on follow up

Page 32: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Fulgaration with resectocope

Page 33: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Case

Ante natal USG s/o left moderate hydronephrosis

Repeat USG, dilatation of upper kidney with hydroureter s/o

duplex system and ureterocele

Page 34: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

VCUG and MRU

Page 35: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Ureterocoel Incision

Page 36: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Repeat USG after 2 wks

Page 37: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

CASE

Antenatal scan 32 wks

Left hydronephrosis AP diam of renal pelvis

11mm

Left ureteric dilatation present

Right Kidney normal

Bladder normal

Page 38: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Post natal

Term male newborn;3kg

Newborn passing urine

Bladder not palpable

Antibiotic prophylaxis

USG KUB after 48-72hrs

AP Diam: 11mm;Ureter dilated

MCU under antibiotic cover

WHAT NEXT

WHAT NEXT

Page 39: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

MCU

• Rt Grade III VUR

Page 40: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

DMSA Scan

• Scarred left kidney

Page 41: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Follow up Advice

Chemoprophylaxis

Early toilet training

Avoid constipation

Perineal Hygine

Growth/BP monitoring

Regular Urine

examination/ultrasounds/DMSA scan

Page 42: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

When to intervene?

Recurrent breakthrough UTI

Progressive scars in DMSA SCAN

Parents choice

Endoscopic injection Vs Ureteric

Reimplantation

Page 43: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

STING technique (Subureteric transurethral injection)

43

Page 44: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

Follow Up

Chemoprophylaxis stopped

Follow up with nephrologist

Page 45: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis

CARRY HOME MESSAGE

Do not ignore ANH even if it is transient

Remember AP diameter of pelvis 4/7/10 mm

Most ANH just need surveillance

Hydronephrosis is not synonymous with obstruction

Be positive, supportive, ANH usually have good prognosis.

Page 46: Antenatal Hydronephrosis(ANH): Surgical Aspects Hydronephrosis(ANH): Surgical Aspects Dr Prashant Jain Sr. Consultant Pediatric Surgery & Pediatric Urology ... Rt AP diameter of pelvis