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ANIMAL ACTION REPORT ADVANCING SCIENCE WITHOUT HARMING ANIMALS A PUBLICATION OF THE NATIONAL ANTI-VIVISECTION SOCIETY FALL 2012 www.navs.org By Dr. Brian Jones and Dr. Rodger Curren Continued on page 5 ADDRESSING THE CRUELTY-FREE DILEMMA In the late eighties and early nineties many animal protection groups and concerned consumers claimed significant victories as major cosmetics companies placed specific limits on—or completely stopped—animal testing for cosmetics and personal care products and their ingredients. But as new (and very large) consumer markets have opened up around the world, new hurdles to “not animal tested” claims appear left and right. As “cruelty-free” companies expand into these new markets, they face government regulations different from and generally much more onerous than those in the United States and Europe.

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Page 1: ANIMAL ACTION REPORT - National Anti-Vivisection Society...ANIMAL ACTION REPORT ... challenging the motives and ethics of a number of companies who have chosen to expand their mar-kets

ANIMAL ACTION REPORT

A D V A N C I N G S C I E N C E W I T H O U T H A R M I N G A N I M A L S

A P U B L I C A T I O N O F T H E N A T I O N A L A N T I - V I V I S E C T I O N S O C I E T Y • F A L L 2 0 1 2

www.navs.org

By Dr. Brian Jonesand Dr. Rodger Curren

Continued on page 5

ADDRESSING THE CRUELTY-FREE DILEMMAIn the late eighties and early nineties many animal protection groups and concerned consumers claimed significant victories as major cosmetics companies placed specific limits on—or completely stopped—animal testing for cosmetics and personal care products and their ingredients. But as new (and very large) consumer markets have opened up around the world, new hurdles to “not animal tested” claims appear left and right. As “cruelty-free” companies expand into these new markets, they face government regulations different from and generally much more onerous than those in the United States and Europe.

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2 N A V S • F A L L 2 0 1 2

A N I M A L A C T I O N R E P O R TA N I M A L A C T I O N R E P O R T

UP FRONTWITH NAVS

N E W S I T E M S A B O U T A N I M A L A D V O C A C Y

N AT I O N A L H E A D Q U A R T E R S

53 W. Jackson Blvd., Suite 1552Chicago, IL 60604Tel: 312-427-6065

800-888-NAVS(800-888-6287)

Fax: 312-427-6524Email: [email protected]

Visit us on the web: www.navs.org

The National Anti-Vivisection Society is a na-tional, not-for-profi t organization incorporated in the State of Illinois. A copy of NAVS’ annual fi nancial report is available upon request.

The National Anti-Vivisection SocietyAdvancing Science Without

Harming Animals

© 2012 The National Anti-Vivisection Society. All rights reserved. This publication may not be reproduced in whole or in part in any form without prior written permission from the publisher.

E X E C U T I V E D I R E C T O R

Peggy Cunniff

D I R E C T O R O F P R O G R A M S A N D C O M M U N I C AT I O N S

Clare Haggarty

D I R E C T O R O F L E G A L / L E G I S L AT I V E P R O G R A M S

Marcia Kramer

D I R E C T O R O F S C I E N C E P R O G R A M S

Dr. Pam Osenkowski

D I R E C T O R O F F I N A N C I A L O P E R AT I O N S

Elizabeth Zachara

A S S I S TA N T D I R E C T O R O F P R O G R A M S

Laura Ell

M A N A G E R , I N F O R M AT I O N S E R V I C E S

Andre Davis

M A N A G E R O F S P E C I A L P R O G R A M S

Jamie Aitchison

P R O G R A M A S S O C I AT E

Michael Foley

L E G A L R E S E A R C H C O O R D I N AT O R

Ian Bucciarelli

S C I E N C E A D V I S O R S

Eugene Elmore, Ph.D.Bernard E. Rollin, Ph.D.

Sherry Ward, Ph.D.

W R I T I N G

Mary Jane Rumminger

G R A P H I C D E S I G N

Stacy Sweat Designs

Their future depends on you

Your commitment to animals and the struggle to end vivisection is rewarded every time an animal is retired from research, an alternative to animal testing is developed by an innovative sci-

entist, or an entire school district abandons dissection for interactive computer simulations. By remembering the National Anti-Vivisection Society in your will, your legacy will provide greater compassion, respect and justice on behalf of all creatures.

To help you decide which estate planning option is best suited to you, NAVS has published The Legacy of Compassion: A Guide to Chari-table Giving for People Who Care. Please call NAVS at 800-888-NAVS (6287) if you would like a copy of this brochure. Or visit www.navs.org/plannedgiving.

If you wish to remember NAVS in your will, we suggest you consult an attorney, financial advisor or estate planner. Whatever form your gift takes, NAVS suggests the following language be included:

“To the National Anti-Vivisection Society, 53 West Jackson Boulevard, Chicago, Illinois, 60604, I bequest the sum of _______ for the general purposes of the organization.”

We wish to thank all of you who continue giving in an effort to find credible answers for a cruelty-free world.

Help animals sound off on Facebook and Twitter!

A steady way to give

You can help protect ani-mals from the cruelty of vivisection with NAVS’

Automatic Monthly Giving pro-gram. A minimum of $5 can be contributed on the same day ev-ery month automatically via your credit card, checking account or savings account. By taking ad-vantage of Automatic Monthly Giving, you help ensure we have the necessary, steady funding throughout the year to support our program activities. Our an-nual report on page 9 details how funds are spent. Ending the use of animals in science is a long-term struggle. Your ongoing support enables us to maintain a constant presence in the scientific field, en-couraging researchers to develop the alternatives that will one day replace animals.

All donations to NAVS are tax deductible.

Like” us at www.facebook.com/navs.us and join discus-sions on humane treatment

of animals. Recommend us to your friends and keep the voice for animals strong!

The NAVS Twitter feed keeps you current on the issues in ani-mal advocacy. Follow us at www.twitter.com/navs_us, or text “fol-low NAVS_US” to 40404 to get updates via SMS.

Your online presence raises the volume for animals!

Acknowledgement: Publication of this edition of NAVS’ Animal Action Report was made possible, in part, through a generous grant from the Helen Brach Foundation.

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F A L L 2 0 1 2 • N A V S 3

A N I M A L A C T I O N R E P O R TA N I M A L A C T I O N R E P O R T

At NAVS.org, you can:

Sign upReceive our weekly eblasts: Science First and Take Action Thursday.

Search forcruelty-free productsCheck the cruelty-free status of personal care products.

DownloadRead NAVS publications (including back issues of the Animal Action Report).

DonateSet up a monthly donation to either our General Fund or Sanctuary Fund.

Take actionSend letters on behalf of animals directly to legislators and decision makers.

Visit www.navs.org today and tell us what you think!

NAVS is pleased to announce the completion of our new and improved website, www.navs.org. As always, NAVS.org provides the most comprehensive, up-to-the-minute information on issues related to animals exploited in biomedical research, product testing and education. Our new layout and functionality offer users a simple way to navigate an often complex subject and to take action for animals.

Your mouse won’t believe how easy it is!

Scurry to the new NAVS.org!

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4 N A V S • F A L L 2 0 1 2

A N I M A L A C T I O N R E P O R T

2nd Place Adult:Ashley Senese, Speak, See, Hear No Evil

If a picture is worth a thousand words, the theme for NAVS’ Art for Animals 2012—“Being

a Voice for Those Who Cannot Speak for Themselves”—al-lowed artists of all ages and all disciplines to produce a roaring outcry on behalf of animals.

Art for Animals provides a non-monetary way to help NAVS spread our message of compassion and respect for animals. Compelling artwork has the ability to educate and inspire in a way mere words cannot. Our hope is that the artwork below will raise awareness about the exploitation of animals, and motivate people to take action.

NAVS extends a heartfelt “Thank You!” to everyone who participated in Art for Animals 2012. Congratulations to all the winners and honorable mentions! Visit www.navs.org to view an online gallery of winners from this and past competitions.

Congratulations to the winnersof Art for Animals 2012!

3rd Place Adult:Kevin Haseman, Can We Go Home

Best in Show:Conrad Javier, Free the Voice

Best Photo:Lindsay Phillips, Confinement

1st Place Adult:Joan Share, Connected

ConnectedDoes your own heart feel imprisonedWhen I look out from my cageDo you feel a twinge of heartacheFrom the sadness in my gaze

When I lift my paw to touch youWill you hold it in your handAnd embrace it with compassionSo I know you’ll understand

Would the water from my own tearsCause your eyes to cryAs I tremble from my own fearsWould you need to question why

When others try to hurt meTo accomplish their own endPlease do not desert meI need you as my friend

If you see someone abuse meWould it hurt you to the coreWould it make you want to shout and pleadNo more, no more, no more

You and I, we’re not so differentAs the world might choose to thinkFor our souls remain connected By a universal link

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F A L L 2 0 1 2 • N A V S 5

A N I M A L A C T I O N R E P O R T

Regulations in these new mar-kets often require companies to conduct animal testing before they can sell their products. Even though some alternative meth-ods have been accepted in recent years, countries such as China, Russia and Brazil initially required the animal testing of certain prod-ucts and ingredients for such end-points as oral toxicity (general poisoning), skin and eye irritation, and skin sensitization (allergy). While some companies chose not to enter these markets because it would require them to return to testing on animals, some moved into these countries regardless of the testing or because they were unaware of the requirements. Still Continued on page 6

Continued from page 1 others moved ahead into these countries since their publicly-stated pledge to consumers to do animal testing only “where required by law” wasn’t being broken. Because these tests were being done under legal require-ments, it was generally seen by company management as a rea-sonable step to take.

However, consumers and ani-mal protection groups are now challenging the motives and ethics of a number of companies who have chosen to expand their mar-kets and comply with the animal testing requirements in these new markets. Over the next year or two we should see what effects various recent calls to action, and in some cases legal proceedings, will have

in this quite volatile and emotion-ally charged arena.

A variety of laws and enforcement

Adding to the confusion sur-rounding whether or not a com-pany should begin selling cosmet-ics and personal care products in a country that has some type of animal testing requirement for products, ingredients or both, is the fact that each country seems to enforce these requirements dif-ferently. Certainly the country that requires the greatest amount of animal testing for cosmetics in-gredients and cosmetics is China.

Required use of animals for

product safety testing in

China and other countries

is creating a fi restorm of

protest against “cruelty-

free” companies who enter

these markets. For the

cosmetics and personal care

industry, global expansion

comes at the price of

potential boycotts at home.

The NAVS website maintains

a databank of companies

that do and do not follow

cruelty-free policies here and

abroad. While boycotting

sends an important message,

the solution to ending this

cruelty to animals must be

addressed on a grander

scale. NAVS is a proud

fi nancial supporter of the

International Outreach

Program described in this

article. The International

Foundation for Ethical

Research—which is funded

by NAVS—also approved

a grant to support this

effort. Read how dedicated

scientists are bringing their

non-animal testing methods

to developing countries

around the world.

ADDRESSING THE CRUELTY-FREE DILEMMA

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A N I M A L A C T I O N R E P O R T

animal testing for cosmetics. How-ever, over the last few years Brazil has limited requests for such tests for many regulatory submissions. Additionally, Brazil has shown an increasing interest in the ap-plicability and use of alternative methods to animal testing. In 2008, new legislation was adopted that regulates the use of animals for scientific purposes and requires monitoring of implementation of alternative methods (Law n. 11.794, 200). Since that time, sev-eral companies have been estab-lished that promote the use of in vitro testing and, more recently, a Brazilian Center for the Valida-tion of Alternative Methods was created.

In Russia, regulators have started to accept specific, unique, non-animal methods for irritation and toxicity, and some products are granted regulatory approval without any animal testing. For various reasons related to this adoption of non-animal methods

and review policies, the number of animals used has been greatly re-duced. However, should a product fail one of these Russia-specific non-animal methods, then ani-mal testing or reformulation of the product is required. Recently, however, there are indications that more standardized Organisation for Economic Co-operation and Development (OECD) in vitro Test Guideline1 methods will begin to be incorporated into Russian regulatory strategy.

Initially one might think these governments are somewhat bar-baric and callous to the pain and suffering of animals, when the use of in vitro methods is so common elsewhere. However, perhaps we should not be too harsh in judging regulators in these countries for requiring the use of animal testing. For instance, each of these gov-ernmental agencies is relatively new in the global marketplace of cosmetics. They have not had the opportunity to gain experience

and understanding of safety and risk assessment for ingredients and products, while many inter-national companies and “Western” agencies have had decades to do so. Secondly, they have not had the training or exposure to non-ani-mal methods to replace or reduce the current requirements for ani-mal testing and, most important, each of these countries—Brazil, China, Russia—has asked for as-sistance in the form of training in non-animal methods for use in assessing the safety of cosmetics and raw ingredients.

Our goal moving forward: education and training in developing markets around the world

To address the request and needs for education and training in these countries, the Institute for In Vitro Sciences (IIVS) has

These requirements have been in place since 1990, initially under the direction of the Chinese Min-istry of Health (MOH). Ironically, these regulations were initiated about the same time many U.S. and European companies began placing restrictions on, or totally prohibiting, animal testing for their products.

Today, the China State Food and Drug Administration (sFDA) oversees the regulation of cos-metics products and ingredients produced and sold within China. In addition to the need for animal testing to obtain premarket ap-proval for sales within China, there is also the potential for animal testing of products and ingredi-ents when they are imported into China. This testing is conducted by the Customs, Inspection and Quarantine authority and is re-quired for most, if not all, ingre-dients and products brought into the Chinese market.

On the positive side, there are many scientists in China who are actively investigating non-animal methods. There are websites (e.g., www.vitrotox.com) describing ad-vances in in vitro (non-animal) techniques, and there are even books written in Chinese spe-cifically directed at such testing methods. However, it is extremely difficult, if not impossible, for any company—Chinese or non-Chi-nese—to sell products in China without some type of animal test-ing.

The situations in Brazil and Rus-sia are slightly different. Both of these countries retain require-ments for animal testing on their regulatory “books” and thus have the potential to ask for premarket

INITIALLY ONE MIGHT THINK THESE GOVERNMENTS ARE SOMEWHAT BARBARIC AND CALLOUS TO THE PAIN AND SUFFERING OFANIMALS, WHEN THE USE OF IN VITRO METHODS IS SO COMMON ELSEWHERE. Continued from page 5

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F A L L 2 0 1 2 • N A V S 7

A N I M A L A C T I O N R E P O R T

started two outreach programs. For those that may not know much about IIVS, it was founded in 1997 as a non-profit corporation dedi-cated to the advancement and utilization of non-animal meth-ods. IIVS operates as a center of excellence for in vitro methods used for product safety testing purposes. This includes providing not only laboratory contract ser-vices to hundreds of companies, but also training and education in non-animal methods to compa-nies and governmental agencies at their Gaithersburg, Maryland, laboratories. These rigorous sci-entific programs, coupled with educational and outreach initia-tives, have established IIVS as a global leader in the advancement of alternatives to animal testing.

The first IIVS outreach program is the International Outreach Pro-

gram (IOP), which has support from individuals, companies, animal protection organizations (including the National Anti-Vivisection Society), and other agencies interested in reducing or eliminating the need for ani-mal testing around the world. The IOP has recently supported three major outreach efforts. The first was for IIVS scientists to travel to China and work with Chinese experts on the 3T3 Neutral Red Phototoxicity assay. The Guang-dong Center for Disease Control had been working with the MOH and sFDA for many years to have the assay approved for cosmetics ingredients. In early November 2011, they requested a forum to discuss the method and a program toward acceptance of this method in China. Along with IIVS, experts from the U.S., Japan and China also attended a two-day discussion on the method. In February 2012, the sFDA presented the method for discussion with the expectation that the assay would be accepted

by late summer or early fall of 2012. This is a significant success by the Chinese government. Should the method be accepted as expected, the sFDA will have approved their first non-animal test method in less than one year from their first review. There is also a possibility that two more methods could be reviewed by the end of 2012.

The IOP also supported a labo-ratory workshop and training in Brazil in November of 2011. The Brazilian workshop was held at the Federal University of Goiás and was open to scientists from gov-ernment, industry and academia to promote the understanding and harmonization of non-animal methods across these many sec-tors. The program consisted of a combination of lectures and hands-on demonstrations of several in vitro methods, includ-ing eye irritation: OECD TG 437 (BCOP), phototoxicity: OECD TG 432 (3T3NRU PT), skin corrosion: OECD TG 435 (membrane barrier test), and starting doses for acute

toxicity: OECD TG 129 (3T3 NRU). Based on their experience from

this workshop, Brazilian scientists expressed an interest in learning even more about the regulatory application of in vitro test meth-ods. In response, IIVS is planning future practical workshops in Brazil with the help of Brazilian experts. The aim of these future workshops is to provide scientists with a theoretical and practical understanding of the application, laboratory procedures and data interpretation of in vitro meth-ods, such that they can be used to remove all need for animal test-ing as a potential requirement for cosmetics.

The most recent effort of the IOP was working with Russian regula-tors and scientists responsible for the safety evaluation of cosmetics ingredients and products. In late June 2012, IIVS hosted a four-day workshop for eleven attendees, mostly involved in regulatory activities, from Russia. Through

Continued on page 8

THE FIRST IIVS OUTREACH PROGRAM IS THE INTERNATIONAL OUTREACH PROGRAM (IOP), WHICH HAS SUPPORT FROM INDIVIDUALS, COMPANIES, ANIMAL PROTECTION ORGANIZATIONS (INCLUDING THE NATIONAL ANTI-VIVISECTION SOCIETY), AND OTHER AGENCIES INTERESTED IN REDUCING OR ELIMINATING THE NEED FOR ANIMAL TESTING AROUND THE WORLD.

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8 N A V S • F A L L 2 0 1 2

A N I M A L A C T I O N R E P O R T

tion of non-animal methods in countries that have the potential to request, or absolutely require, animal testing for registration of various products. There are many advantages to having a group of companies working together in these efforts. In addition to be-ing able to combine company resources into a single cohesive effort, there is also the advantage of representing many companies with one unified voice to govern-ment officials. These government officials typically have little free time for meeting with individual companies. Having many com-panies represented collectively is incentive for officials to attend meetings with a single group, e.g., IIVS, as the meeting will be more impactful and productive.

Working through IIVS, this pro-gram provides impartiality to the discussions. IIVS is a representa-tive for the methods and their effective use, not for a specific company, product or ingredient, and IIVS does not sell product in

these countries. Through support of the IOC, several trips have been conducted to China and have laid thegroundwork for many future efforts: lectures at conferences and universities, evaluation of im-portant tissue models developed within China, and basic plans to establish training laboratories in

several regions in China. We are entering an important phase in the development and acceptance of non-animal methods, not un-like the efforts given during the 80s and 90s by individuals, non-governmental organizations and companies alike.

These efforts still require addi-tional support and guidance, and not all activities or efforts will be an immediate success. However, great progress has already been made in these three markets—China, Russia, Brazil—since IIVS established these programs a little more than one year ago. As the world turns, we also hope that it grows smaller, at least in regard to those countries that still look for the use of animals to determine the safety of cosmetics products and ingredients. It will take time, but eventually all countries will be comfortable in allowing the sale of cosmetics and personal care products that have never been tested on animals. 1 The OECD Guidelines for the testing of chemicals are a collection of internationally agreed testing methods used by governments, industry and independent laboratories to assess the

safety of chemical products.

Dr. Brian Jones is the director of education and outreach at the Institute for In Vitro Sciences, Inc. His career-long dedication to in vitro methods of product safety testing includes pioneering efforts to introduce animal testing alternatives to China.

Dr. Rodger D. Curren is a co-founder and president of the Institute for In Vitro Sciences, Inc. The recipient of many honors for his contributions to the in vitro fi eld, Dr. Curren serves on various national and international committees and science advisory boards, including the International Foundation for Ethical Research, focused on alternatives to whole animal testing.

a combination of lectures and hands-on laboratory training, the delegates gained firsthand knowledge of how non-animal test methods can be used to assess the safety of ingredients, cosmet-ics and personal care products. As in Brazil, Russian scientists were impressed with the sophis-tication of the methods taught. Additional training sessions in Maryland and Russia are already being planned to occur in the coming months. Opportunities to expand the knowledge of non-animal methods to areas outside of cosmetics will also be available through various Russian organi-zations and conferences arising through relationships established during this workshop.

The second of IIVS’ outreach programs is the International Outreach Consortium (IOC). The IOC is composed of companies from various industrial sectors dedicated to working together to support the training and educa-

THROUGH A COMBINATION OF LECTURES AND HANDS-ON LABORATORY TRAINING,THE DELEGATES GAINED FIRSTHAND KNOWLEDGE OF HOW NON-ANIMAL TEST METHODS CAN BE USED TO ASSESS THE SAFETY OF INGREDIENTS, COSMETICS AND PERSONAL CARE PRODUCTS.

Continued from page 7

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NAVS 2011 ANNUAL REPORT

F A L L 2 0 1 2 • N A V S 9

JULY 1, 2010 - JUNE 30, 2011

ANNUAL REPORT

Dear NAVS Supporters,

The National Anti-Vivisection Society measures success in terms of the progress we have made toward ending the suffering of animals used in research, product testing and education. As a non-profi t educational organization we are grateful for the position of trust that our supporters have in our efforts as responsible and professional advocates for animals and the advancement of humane science. We acknowledge our responsibility to provide a complete and transparent Annual Report of NAVS’ activities and how our resources have been used.

In measuring our progress in Fiscal Year 2011 we have highlighted specifi c actions taken by NAVS and their impact on the awareness and attitudes of people as well as their actual impact on the use of animals in the name of science. Of course, in order to end the suffering of animals used in science, it is important to note that it is never our efforts alone that deserve credit—the work of countless NAVS supporters and other animal advocates who believe in compassion for all creatures, innovative scientists who recognize the limitations of animal models and the promise of more humane methodologies, responsible government leaders and policy makers, private industries that are sensitive to their responsibilities to profi t without cruelty to animals, and the media for shining a spotlight on animals and how they are treated in our society—all contribute to changes in the way science is conducted.

NAVS’ specifi c programs and activities are categorized into fi ve general program areas: General Education and Public Awareness, Educational Programs for Students and Teachers, Science Initiatives, Legal/Legislative Efforts, and Special Initiatives and Cooperative Efforts. In addition to the direct costs associated with each of the specifi c programs under these categories, signifi cant general (indirect) expenses have been allocated among the categories, based on a determination of how NAVS’ time and resources are used. These costs include fi xed expenses such as rent, offi ce equipment, salaries, insurance, telephone and other utilities. Additionally, some educational activities and their costs are associated with multiple program areas, such as research and data processing, fulfi llment of requests for information and some meetings, and have been allocated, along with the fi xed program expenses, among the fi ve program categories as “indirect expenses.” If you have any questions on individual programming, please feel free to contact us directly.

Sincerely,

Peggy CunniffExecutive Director

We Educate.We Effect Change.

We Advocate.Advancing humane science requires changing how people think. NAVS takes a coordinated, wide-ranging approach that combines effective advocacy and innovative education. We invite you to review the Fiscal Year 2011 NAVS Annual Report for an understanding of how we work to end the exploitation of animals in product testing, biomedical research and education.

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NAVS 2011 ANNUAL REPORT

1 0 N A V S • F A L L 2 0 1 2

General Education and Public Awareness ProgramsNAVS uses a variety of media to promote its message of compassion, including our website—www.navs.org—social media, mass market and specialty publications, print advertising, TV and radio interviews, letters to the editor, direct mail, conferences, and participation in debates.

Animal Action Reports The NAVS newsletter, Animal Action Report, also available in an electronic format, offers a comprehensive look at issues regarding vivisection and NAVS programs. Each issue featured specifi c programs, legislative endeavors, and the names of recipients of NAVS Sanctuary Fund grants. NAVS is grateful to the Helen Brach Foundation for support of this important publication.

NAVS WebsiteThe NAVS website continues to be a credible resource on the issue of vivisection and is updated with current campaigns and news, providing a valuable resource to one-time and repeat users.

Internet Eblasts NAVS electronic “blasts” were sent to NAVS supporters on a variety of issues, including appeals for the Sanctuary Fund and legislative alerts for important bills.

Social NetworkingNAVS’ online visibility has gained momentum on social networking sites such as Change.org, Facebook, MySpace and Twitter. NAVS has a profi le on Causes.com, End Animal Experimentation, with a growing number of followers. NAVS also posts daily tweets on issues of interest to the animal advocacy community.

Art for Animals 2011 NAVS’ annual art contest received a diverse collection of creative artwork, music, essays and poetry. Winners were announced on the NAVS website, along with pictures of current winning entries. Artwork has been featured throughout NAVS’ printed materials.

NAVS BrochuresThe NAVS general information brochure Taking Action for Animals was in great demand, necessitating a reprint to send to fi rst-time donors and to distribute at NAVS-sponsored events. The NAVS Sanctuary Fund brochure was also reprinted to address the needs of applicants seeking a Sanctuary Fund grant.

Educational Programs for Students and TeachersNAVS believes strongly that no student should be forced to harm animals in pursuit of a science education. More important, our efforts in this area are helping to end the needless suffering of animals by promoting humane education.

NAVS Biology Education Advancement Program (BioLEAP)

This program combines student and teacher counseling with promotion of NAVS’ extensive library of dissection alternatives.

Science Fairs NAVS is the only animal advocacy group offering an award at a national science fair, the Intel International Science and Engineering Fair, where high school students are awarded the Humane Science Award for experiments that advance science without harming animals. NAVS also supports the American Junior Academy of Sciences annual meeting and the Illinois Junior Academy of Science fair.

Science InitiativesNAVS disseminates the most authoritative and persuasive evidence available to advance scientifi c arguments against the use of animals in science. NAVS also continues to invest in the development and validation of alternative methods to the use of animals in product testing, biomedical research and education.

International Foundation for Ethical Research (IFER) IFER was founded in 1985 by NAVS to support scientists who are developing alternatives to the use of animals in product testing, biomedical research and education, especially projects that replace the use of archaic animal models with methodologies that are predictive for human health.

Science First A free e-newsletter, Science First, provides cutting edge science news of the week to subscribers.

Science CornerA regular feature on NAVS’ website, Science Corner, explains and provides context to complicated science issues for the layperson and professionals alike who want to learn more about advancing science without harming animals.

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NAVS 2011 ANNUAL REPORT

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NAVS Board of Directors

Kenneth Kandaras, President

Mary Ann Ligon, Vice President

Michael B. Mann, Secretary

J. Patrick Beattie, Treasurer

Peter O’Donovan

National Anti-Vivisection Society53 W. Jackson Blvd., Suite 1552

Chicago, IL 60604Tel: 312-427-6065Fax: 312-427-6524

Email: [email protected]

Legal/Legislative EffortsWorking at the local, state and federal levels of government, NAVS focuses on the constructive use of the legal system to advance greater justice for animals.

Take Action Thursday This free, weekly e-mail alert summarizes federal and state initiativesaffecting animals and asks subscribers to “take action” by contacting their legislators through the NAVS Advocacy Center.

Advocacy CenterNAVS drafts and submits comments on state and federal legislation, submits comments on proposed agency rulemaking, and drafts lettersfor supporters to use to take action through the NAVS website.

AnimalLaw.comAnimalLaw.com is an online resource providing relevant laws and legislation for 50 states and the federal government, along with model laws, case digests, and a weekly update of animal law newsfrom around the world.

International Institute for Animal Law (IIAL) IIAL received a grant from NAVS to promote legal scholarship and advocacy skills in the fi eld of animal law.

National Research Library for Animal AdvocacyIn partnership with The John Marshall Law School, NAVS helps make the National Research Library for Animal Advocacy available to law students and professors around the country through the law school’s inter-library loan program.

Independent Auditor’s Report We have audited the accompanying statement of financial position of the National Anti-Vivisection Society as of June 30, 2011 and 2010, and the related statements of activities, functional expenses, and cash flows for the years then ended. These financial statements are the responsibility of the Society’s management. Our responsibility is to express an opinion on these financial statements based on our audits.

We conducted our audits in accordance with auditing standards generally accepted in the United States of America. Those standards require that we plan and perform the audits to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and the significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of the National Anti-Vivisection Society as of June 30, 2011 and 2010, and the changes in its net assets and cash flows for the years then ended in conformity with accounting principles generally accepted in the United States of America.

Selden Fox, Ltd., Certified Public AccountantsSeptember 1, 2011

gal/Legislative Effforts

Special Initiatives and Cooperative EffortsNAVS is committed to supporting a variety of special initiatives, both within our organization and in cooperation with other animal advocacy groups. These efforts help save animal lives today while paving the way for long-term and positive change for animals.

NAVS Sanctuary Fund Grants NAVS awarded thousands of dollars as grants for emergency assistance to animal shelters and rescue operations. More than half a million dollars of grant money has been distributed to hundreds of groups since the inception of the NAVS Sanctuary Fund. Individual recipients are reported in the NAVS Animal Action Report and on the NAVS website.

Miscellaneous Small Grants NAVS continues to support the efforts of like-minded organizations whose works refl ect the mission of NAVS. NAVS supported the work of the National Council for Animal Protection, a professional association of national animal advocacy leaders, and provided a grant to the Humane Research Council to conduct a study to assess the progress of the animal protection movement.

The National Anti-Vivisection Society (NAVS) is dedicated

to ending the exploitation of animals used in science.

The NAVS Mission

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NAVS 2011 ANNUAL REPORT

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2010 2011

PROGRAM AND EDUCATION

68.87% 69.29%

General Education/ Public Awareness 61.34%

Student/ Teacher Outreach 4.23%

Legal/Legislative 13.66% Science Programs 10.84%

Special Initiatives/ Cooperative Efforts 9.93%

ADMINISTRATIVE11.39% 11.18%

FUNDRAISING19.74% 19.53%

TOTAL REVENUE (2011) $3,349,555

TOTAL EXPENSES (2011) $2,584,035

FUNCTIONAL BREAKDOWN OF EXPENSES

Program& Education$1,790,548

Fundraising$504,609

Administrative$288,878

69.29%

19.53%

11.18%

JULY 1, 2010 TO JUNE 30, 2011

More Than Just Numbers Investing in humane science for a cruelty-free future

NET ASSETS

Restricted: Special ProjectSanctuary Fund $144,798

Investment 286,879

Unrestricted 5,374,144

TOTAL NET ASSETS $5,805,821

TOTAL LIABILITIESAND NET ASSETS $5,842,747

LIABILITIES AND NET ASSETS

CURRENT LIABILITIES

Accounts Payable $6,024

Accrued Expenses 548

Accrued Vacation 30,354

Total Current Liabilities 36,926

TOTAL LIABILITIES $36,926

INVESTMENTS

Common StocksMkt. Value $4,949,875

Investments Restricted 286,879

TOTAL INVESTMENTS $5,236,754

ALL EXPENSES PROGRAM AND EDUCATION EXPENSES ASSETS

CURRENT ASSETS

Cash and Cash Equivalents $525,216

Prepaid Expenses 24,156

Accrued Interest Receivable 2,821

Property and Equipment 53,800

TOTAL ASSETS BEFORE INVESTMENTS $605,993General Education/

PublicAwareness$1,098,303

Science Programs$194,059

Legal/Legislative

$244,559

SpecialInitiatives/CooperativeEfforts$177,850

Student/Teacher

Outreach$75,777

The balance sheet for Fiscal Year 2011 summarizes the assets, liabilities and net assets of the National Anti-Vivisection Society.

NAVS earns its revenue in three major ways: funds from operations, which include new memberships, membership renewals, donations, literature sales and grants received ($995,262); non-operation funds such as interest and dividends ($1,040,538); and funds from bequests and legacies from our sup-porters ($1,313,755).

As a non-profi t organization, NAVS’ main fi nancial goal is to direct the maximum amount of our resources to our educational programs. The accompany-ing chart shows how the money was spent: 69.29 percent of our resources were directed to educational programs, 11.18 percent to administrative costs and 19.53 percent to fundraising expenses.

Educational expenses include all of NAVS’ programs – the NAVS Animal Action Report and other publications, our extensive public awareness programs (which utilize a variety of media), the operation of BioLEAP, and our support of IFER, AFMA and IIAL, all of the programs that keep members apprised of developments in anti-vivisection issues, and accurate, persuasive education programs to acquaint the public with the issues and inform them of how they can make a difference for the animals.

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Continued on page 14

Walking into the exhibi-tion hall on the first day of judging at the Intel

International Science and Engi-neering Fair (Intel ISEF) one be-comes witness to a celebration of scientific innovation and imagina-tion. Approximately 1,200 projects are neatly arranged in rows, each one the culmination of months or sometimes years of scientific in-quiry by high school students from around the world. Their work has already been judged as excellent in regional competitions.

Some historyWith more than a dozen catego-

ries from Animal Science to Plant Science to consider, NAVS over the years has recognized winners who exemplify the principles of our Humane Science Award in many different fields. The NAVS judges review projects for both their sci-entific excellence and how they advance science without harming animals.

Why has NAVS been awarding prizes to students at Intel ISEF for the past 11 years? After moni-toring science fairs in the 1990s and observing numerous student projects that caused harm and even death to animals, NAVS saw the need to press for changes to the rules of qualification. It took a shareholders’ resolution to finally get the attention of Intel Corpo-ration, now sponsor of the fair, and Society for Science and the Public, who administers it. Over time, this has led to progress in establishing rules that promote humane science. Additionally,

Future Scientists Inspire Hope at Intel ISEFNAVS Humane Science Award Marks 11th year

In summary, the winners of the 11th NAVS Humane Science Award at Intel ISEF are:

DavidLiu(Far right)

MEDICINE AND HEALTH

Synthetic Nanoparticle-Based Nanozymes for Pancreatic Cancer Therapy

RaghavTripathi(Second from right)

CELLULAR AND MOLECULAR

Biology—Toward the Cure: Abnormal Protein Interactions between Amyloid Beta and Tau as a Therapeutic Target for Alzheimer’s Disease

Samantha Marquez(Left)

ENGINEERING: MATERIALS

AND BIOENGINEERING

A New Frontier in Biomedical Engineering: Ex-situ Bioengineering of Hepato- & Neuro-Celloidosomes

1st place 2nd place 3rd place

Why has NAVS been awarding prizes to students at Intel ISEF for the past 11 years? After monitoring science fairs in the

1990s and observing numerous student projects that caused harm and even death to animals, NAVS saw the need to press

for changes to the rules of qualifi cation.

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animals at such a preliminary stage of experimentation would be a waste of resources. I think it’s immature to do less than one year of experimentation and go straight to animal testing.” David added: “With such powerful tools available nowadays, we don’t need to be so reliant on using animals for experimentation and education. I think computer and mathematical models are the way to go.” In addition to winning the NAVS first-place prize, David was awarded a four-year scholarship to the Florida Institute of Tech-nology for his work, another sign of the excellence of his project.

Second-place winner, Raghav Tripathi, chose to do his research on Alzheimer’s disease—in part because of his grandfather’s health. He was offered the choice of an animal or non-animal mod-el to begin his research but felt

NAVS negotiated the opportunity to reward those students whose projects advance humane science. Our purpose is to create a positive incentive for future outstanding scientists to pursue ethical careersthat do not exploit animals.

This year’s winners speak about humane science

In 2012 the change is real, as evidenced by this year’s winners. When asked about their choice of project and what considerations they used in choosing a non-animal model, NAVS received responses that showed a huge shift in the way young scientists viewed the use of animal models. David Liu, this year’s first-place winner, asserted: “I think using

that human tissue and computer modeling would better further his investigation. According to Raghav, “Human tissue is read-ily available and we need to change the research field from the ground up; to change re-search at its core.” His own per-sonal ethical conviction defined his project and he was rewarded not only by NAVS, but by Intel. They awarded him “best” in his category as well as the first-place prize in his category. Raghav also won the European Union Contest for Young Scientists and its trip to Europe.

Samantha Marquez, who chose to work in bioengineering, de-signed and fabricated 3-D orga-nized cell structures called “cel-loidosomes” that can be used to replace animal testing with in vitro organ and organism models. Sa-mantha explained, “I see the future

of the celloidosome in replacing some of the current methods of animal testing by providing a hu-mane, accurate alternative in the form of in vitro tissues that closely mimic organs, glands, and organ-ism functions inside the body. One of the goals of my research is to substitute current animal models with the in vitro humane celloido-some model.” In thanking NAVS for the award, Samantha offered, “We need to recognize that being conscious of the environment and humane towards animals goes farther than sensitivity: it is about our humanity.” Samantha’s project also won the first-place prize in her category from Intel Corporation.

Congratulations to the 2012 win-ners of the NAVS Humane Science Award, as well as to hundreds of other students who believe that all science should be “humane” science.

“I think using animals at such a preliminary stage of experimentation would be a waste of resources. I think it’s immature to do less than one year of experimentation and go straight to animal testing.”

David Liu, 2012 fi rst-place winner

Continued from page 13

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The purpose of offering the NAVS Humane Science Award at Intel ISEF is to

prove that humane science is better science and to encour-age the best and brightest young science students to pursue ca-reers in science without harm-ing animals. The NAVS judges eagerly return each year because of the encouraging response that they receive from these students who “get it!”and have embraced what NAVS has stood for since our founding in 1929. These students are making their mark using hu-man cells, tissues and organs in their quest for discovery and find-ing “humane solutions to human problems.”

This year NAVS was assisted by both veteran and novice judges to review the projects for their scientific merit. According to Dr. Eugene Elmore, a cell biologist at the University of California at Ir-vine, who volunteers as a NAVS sci-ence advisor and long-time judge for the NAVS Humane Science Award: “Each year I am impressed with the quality of the scientific projects and the exceptional ex-pertise demonstrated by the stu-dents. It is a difficult task to select just three of the many exceptional projects. Based on their quality of science and insights into difficult problems, I am convinced that the future of science is in good hands. We have a lot to look forward to from these capable and aspiring young scientists.”

Dr. Pamela Osenkowski, NAVS director of science programs, at-tended Intel ISEF for the first time this year, and brought a fresh new perspective to the judging. “I had heard a lot about what it is like to be a judge at Intel ISEF from the NAVS staff, but I was completely blown away by the magnitude of the science fair and by how en-thusiastic and bright the students were!” Dr. Osenkowski, who also

Judging Projects at Intel ISEF

teaches at Loyola University in Chicago, reveled in the Intel ISEF experience which celebrates the accomplishments of high school students. After the fair she report-ed: “I think it is wonderful that NAVS recognizes young scientists early in their careers with the Hu-mane Science Award. I am proud to work for the only animal advo-cacy group that gives an award at Intel ISEF and look forward to judging the science fair in years to come.”

Another veteran of Intel ISEF, NAVS executive director Peggy Cunniff, has often said that pre-senting the prizes to students at

Intel ISEF is a highlight of her year. “When the students hear their names called and literally come running up to the stage to receive their certificates, I can see that there is a real sense of excitement and pride in their faces. The hand-shakes—and often the hugs—of these students remind me of how important the NAVS Humane Sci-ence Award is to them. The NAVS award lets them know early in their careers that they are on the right track.”

Each winner of the NAVS Hu-mane Science Award and all the students and teachers present at the Intel ISEF who enthusi-

astically applaud them are real signs of progress and hope. How-ever, we know that our work is not done until this science fair prohibits projects that cause any harm to any animals—or all of the students themselves pursue scientific discovery with innova-tive methodologies that do not use animals. Knowing that many of these students in the past have gone on to win Nobel prizes for sci-ence and become leaders in their fields, NAVS will continue to invest in these brilliant young scientists. They can change the course of science and end the cruelty and waste of animal research.

(Above, L-R) Dr. Eugene Elmore, David Liu, Raghav Tripathi, Samantha Marquez, Peggy Cunniff, Dr. Pam Osenkowski

(Left) 2012 winners at Intel ISEF receive many awards for outstanding projects

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Meet the animalsyou’ve helpedYour special donations to the NAVS Sanctuary Fund continue to provide emergency as-

sistance to animals in need. One hundred percent of donations to this fund goes to the aid of animals suffering as a result of natural disaster, neglect or cruelty. Below are stories

about some of the animals you’ve helped.

Please help us keep funds at the ready to answer the many calls for help, each of which is carefully screened. Meet some of your newest friends below!

Ways to donate:

• Visit www.navs.org• Call 800-888-NAVS(800-888-6287)• Return the donor form on page 19

SPEAK UP FOR HORSES in Falmouth, KY, advocates on behalf of horses that have been neglected, abused, discarded, or bound for slaughter. They also provide rescue and rehoming efforts and educate the public about horse slaughter, horse welfare laws, and what it means to be a responsible horse owner. A NAVS Sanctuary Fund grant was awarded to help purchase grass and hay, a scarce commodity as a result of this summer’s drought.

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SAFE HAVEN FOR CATS is a no-kill shelter for cats in Raleigh, NC. In addition to providing adoption services for cats and kittens in need of good homes, they also assist the community in providing spay/ neuter services in connection with a local clinic. A NAVS Sanctuary Fund grant was awarded to help cover costs incurred when they rescued several cats from hoarding situations.

CEDARHILL ANIMAL SANCTUARY in Caledonia, MS, is currently home to approximately 300 animals including cats, dogs, pigs, horses, tigers and lions. They provide lifetime care for all of the animals at the sanctuary. A NAVS Sanctuary Fund grant was recently awarded to help Cedarhill transport and care for two lions and four tigers relinquished from a roadside zoo.

JUNGLE FRIENDS PRIMATE SANCTUARY in Gainesville, FL, provides a permanent safe haven for abused or unwanted primates who are cast off from the pet trade, retired from research, or confiscated by authorities. The animals in their care live in large habitats designed to promote normal behaviors, natural enrichment, and socialization and companionship of other monkeys. A NAVS Sanctuary Fund grant was awarded to build a new habitat for two capuchins retired from a university psychology department.

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PEACE RIVER REFUGE & RANCH in Zolfo Springs, FL, is a lifetime care sanctuary for non-releasable wild animals. The animal residents—who range from big cats to bears, wolves, primates, bats and more—have been used in research, abandoned, or have been kept as “pets.” Peace River provides the space and peace they need to heal and thrive. A NAVS Sanctuary Fund grant was awarded to help defray costs associated with relocating the sanctuary and its residents.

FORT COLLINS CAT RESCUE & SPAY/NEUTER CLINIC in Fort Collins, MO, is dedicated to the well-being of all cats and dogs in the community. Their emphasis is on preventing pet overpopulation and on the sheltering and placement of surrendered or abandoned cats into loving, permanent homes. A NAVS Sanctuary Fund grant was awarded to help sterilize, vaccinate and microchip pets of qualifying low-income residents.

DUTCHESS COUNTY SPCA in Hyde Park, NY, rescues, shelters, and secures permanent homes for adoptable companion animals. They also advocate for the highest standards of animal care and enforce animal cruelty laws throughout Dutchess County. A NAVS Sanctuary Fund grant was awarded to help subsidize medical and boarding costs for over 400 cats rescued from two separate hoarding situations.

BORN FREE USA PRIMATE SANCTUARY in Dilley, TX, offers more than 500 primates (many of whom were rescued from abusive situations in laboratories, roadside zoos, and private possession) life in as natural an environment as possible with minimal human interference. A NAVS Sanctuary Fund grant was awarded to help transport 112 macaques from a defunct sanctuary.

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PLEASE DONATE TODAY

• Name

• Address

• City, State, Zip

•Daytime phone

• E-mail

• Print name as shown on card

• Signature

COMPLETE AND RETURN THIS FORM OR GO TO WWW.NAVS.ORG TO SUPPORT NAVS’ HUMANE SOLUTIONS TO HUMAN PROBLEMS

Our life-saving work depends on the generosity of people like you.

YES! I want to partner with NAVS to help spare animals from the

cruelty and waste of animal experimentation. My gift to sponsor all

NAVS’ educational and advocacy programs: (Check one)

I would like to learn more about leaving a bequest to NAVS. Please send me a complimentary copy of The Legacy of Compassion. (Or visit www.navs.

org/plannedgiving.)

I want to support the NAVS Sanctuary Fund with my gift of$I want to invest in

NAVS’ efforts to support innovative scientists who are developing alternatives to animals in science with my gift of$

Please sign me up for NAVS Automatic Monthly Giving, as described on page 2.Please charge $ each month to my credit card. I have filled out the credit card information below. (Or go to www.navs.org/

Donate. To contribute via checking or

savings account, please call NAVS at

1-800-888-6287.)

If paying by check, please make payable to NAVS and return with

this form in the envelope provided.

Or mail to: NAVS

3071 Paysphere Circle

Chicago, IL 60674-0030.

All donations are tax deductible to the fullest extent of the law.

If you have any questions about this form or making a donation,please feel free to call us at 800-888-6287.

Sign me up for Take Action Thursday weekly eblast.My e-mail address is printed above.

Sign me up for Science First weekly eblast. My e-mail address is printed above.

Sign me up for all NAVS eblasts.My e-mail address is printed above.

I prefer the online newsletter Animal Action Report;

do not send me the print version.My e-mail address is printed above.

OTHER WAYSTO DONATE:

$25 $50 $250

$Other amount

Please visit www.navs.orgfor more information

$100

NID10

NIF10

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• Total Donation $

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VISA MasterCard Discover AmEx(CIRCLE ONE)

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Non-profit Org.U.S. Postage

PAIDNational

Anti-VivisectionSociety

National Anti-Vivisection Society53 W. Jackson Blvd. Suite 1552Chicago, IL 60604

Return Services Requested

Continued from page 18

PREGNANT MARE RESCUE (PMR) in Watsonville, CA, is dedicated to saving pregnant mares from abuse, neglect and a trip to the slaughterhouse. PMR provides a safe, natural environment for mares to foal and nurture their young in peace before preparing them for loving forever homes. A NAVS Sanctuary Fund grant was awarded to help transport slaughter-bound pregnant mares to the sanctuary.

PROJECT PERRY, THE CENTRAL VIRGINIA PARROT SANCTUARY in Louisa, VA, is dedicated to the rescue, rehabilitation, adoption and sanctuary of parrots living in captivity. They provide a safe place for birds to go when no other options are available. While every effort is made to adopt them out to loving forever homes, birds that are not suitable for adoption remain at the sanctuary in a cage-free flighted environment. A recent NAVS Sanctuary Fund grant helped Project Perry rescue four birds from a hoarding situation.

VOICE FOR HORSES RESCUE NETWORK (VFHRN) in Toledo, OH, is committed to providing humane treatment of horses that are sick, injured, abused, auction/slaughter bound or relinquished by their owners. VFHRN is committed to eliminating the causes of equine suffering through intervention, education and community awareness while promoting humane ethics. A NAVS Sanctuary Fund grant provided funds for the medical care of incoming horses, and to help transport adopted horses to their new homes.

MYSTIC FARM WILDLIFE RESCUE, INC. (MFWR) in Sagle, ID, provides shelter and care for orphaned and/or injured wildlife. Specializing in ungulates—moose, elk, deer—MFWR also provides rescue, rehabilitation and release for animals in their care. A NAVS Sanctuary Fund grant helped MFWR maintain sustainability by providing funds for the executive director’s continuing education in wildlife rehabilitation.

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