8
Since the first Deep Brain Stimula- tion initiative of Tsinghua Univeristy in 2000, PINS Medical has gradually established a multinational corpora tion with headquarter based in Beiji and international business cente Singapore. As an innovative high-tech enter prise with focus on neuromodulation, a variety of clinical products have been developed to date, which include stimulators for deep brain, vagus nerve, spinal cord and sacral nerve stimulation therapies. PINS Medical devotes itself to providing cutting-edge treatments for patients who suffer from neurological disorders such as Parkinson’s Disease, Epilepsy, Chronic Pain and OAB, etc. As part of the “National Engineering Laboratory for Neuromodulation”, PINS Medical works in close cooperation with Tsinghua University and the numerous affiliated clinical centers, becoming a center of attraction for a wide range of professional talents in areas of clinical research, innovative R&D and business management. Since 2008, PINS Medi- cal has developed rapidly in becoming a leading brand in neuromodulation within the Chinese market, due to the success of its creative research platform that efficiency links basic research, R&D of novel products, clinical testing and market entry. With an outstanding reputation as a high-tech healthcare corporation, PINS Medical has a primary mission for providing innovative, high-quality products and services for patients to improve quality of life. PINS, which stands for Programma- ble Implanted Neuromodulation Stimulator, is also an abbreviation of “Patient Is No.1 alwayS”. This clearly presents the goal of PINS Medical for “restoring hope”, not simply as an innovation company but also across society to citizens. Looking into the future with the continuous rise in incidence of neuropsychiatric disorders and increased social burden across the globe, PINS Medical along with local governments, research centers, companies and top academic scien- tists, are now developing and promoting innovative therapies worldwide. y a- ing er in ch enter-

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Page 1: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

Since the first Deep Brain Stimula-

tion initiative of Tsinghua Univeristy

in 2000, PINS Medical has gradually

established a multinational corpora

tion with headquarter based in Beiji

and international business cente

Singapore. As an innovative high-tech enter

prise with focus on neuromodulation, a variety of

clinical products have been developed to date, which include stimulators for deep brain, vagus nerve, spinal cord and

sacral nerve stimulation therapies. PINS Medical devotes itself to providing cutting-edge treatments for patients who

suffer from neurological disorders such as Parkinson’s Disease, Epilepsy, Chronic Pain and OAB, etc.

As part of the “National Engineering Laboratory for Neuromodulation”, PINS Medical works in close cooperation with

Tsinghua University and the numerous affiliated clinical centers, becoming a center of attraction for a wide range of

professional talents in areas of clinical research, innovative R&D and business management. Since 2008, PINS Medi-

cal has developed rapidly in becoming a leading brand in neuromodulation within the Chinese market, due to the

success of its creative research platform that efficiency links basic research, R&D of novel products, clinical testing and

market entry.

With an outstanding reputation as a high-tech healthcare corporation, PINS Medical has a primary mission for providing

innovative, high-quality products and services for patients to improve quality of life. PINS, which stands for Programma-

ble Implanted Neuromodulation Stimulator, is also an abbreviation of “Patient Is No.1 alwayS”. This clearly presents the

goal of PINS Medical for “restoring hope”, not simply as an innovation company but also across society to citizens.

Looking into the future with the continuous rise in incidence of neuropsychiatric disorders and increased social burden

across the globe, PINS Medical along with local governments, research centers, companies and top academic scien-

tists, are now developing and promoting innovative therapies worldwide.

y

a-

ing

er in

ch enter-

Page 2: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

The Michelson Medical Research Foundation and the

Human Vaccines Project congratulate the 2019

recipients of the Michelson Prizes for Human

Immunology. These $150,000 awards support young

investigators applying disruptive research concepts to

advance vaccine and immunotherapy discovery

across major diseases.

Winners were selected via a rigorous global

competition and will receive their awards at the

2nd annual conference, The Future of Vaccine and

Immunotherapy Development, at the University of

California, Los Angeles, in June.

THE 2019

MICHELSON PRIZE

WINNERS

COULD YOU BE THE NEXT

MICHELSON PRIZE WINNER?

If you are a researcher under age 35 with an

innovative research concept, apply for the 2020

Michelson Prizes.

Applications open September 9, 2019

www.humanvaccinesproject.org/MichelsonPrizes

Murad Mamedov (UCSF):

Mapping γδ T Cell Receptor Ligands

Kamal Mandal (UCSF):

“Structural surfaceomics:” an approach

to identify cancer-specific cell surface protein

conformations for immunotherapeutic targeting

Avinash Sahu (Dana Farber):

Identification of cancer drugs

that boost immunotherapy response

Page 3: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

For adetailedbrochure,please call (800) 252-4910

All prices are per person twin share + air

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AAAS Travels on fascinatingtrips to all 7 contintents!

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Angkor Wat &Bintan Island“Ring of Fire”December18-27,2019

Where

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for scientists and STEM enthusiasts alike. It’s “Where

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Page 4: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

Science Translational Medicine publishes peer-reviewed, cutting-edge biomedical

research in the felds of cardiology, cancer, immunotherapy, infectious diseases

and vaccines, bioengineering and devices, neurology and neurodegenerative

diseases, obesity, diabetes andmetabolic disorders, drug discovery, genomic

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Page 5: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

Science Immunology publishes original, peer-reviewed,

science-based research articles that report critical advances

in all areas of immunological research, including important

new tools and techniques.

Formore information: ScienceImmunology.org

Publish your research

in Science Immunology

Page 6: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

new productsLIFE SCIENCE TECHNOLOGIES

1198 21 JUNE 2019 • VOL 364 ISSUE 6446 sciencemag.org/custom-publishing SCIENCE

Produced by the Science/AAAS Custom Publishing Office

Wide-Mouth Bottle and Cap System

Designed to help scientists accommodate

sample quantities from 250 mL to 20 L, the

Media Bottle and Multiport Cap System

� !"!�����������!���!��! �� �� !���"�

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collection and storage. The wide neck simpli-

�! ��"�� !"��� ����! ����������������!" ��

pastes, granules, and liquids. Spoons, spatu-

las, tweezers, and large funnels are easily ma-

nipulated through the opening. Made from 33

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resistant to acids, corrosive chemicals, and thermal shock, withstand-

ing temperatures as high as 500∞C���������������������������������

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���������������������������������������� ���������������������������

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DWK Life Sciences

For info: 800-225-1437

������������� �����

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this

space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not

implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/about/new-products-section for more information.

Automated NGS Library Prep

�! ���! ����!���� � ���������! !���! �� � �����������!������

experiments, with the epMotion 5073m NGS solution from Eppendorf.

Until now, automated construction of next-generation sequencing (NGS)

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which is timely and can incorporate pipetting errors. epMotion can

process up to 24 samples simultaneously in a fully automated fashion.

��������� ! �������� ! �� ����� ��� �� � ���!���� �� ��������! �

required single- and multichannel pipetting tools with a range of

5 µLñ300 µL, and a special rack that accommodates all required solutions.

�� �������� �� ��� ����� ! � � �� �� !�� ������ ����� �� �������-

channel dispensing tools to optimize pipetting steps and tip use, even in

�� �� �������� ��� ���� !���� ��� �� � ���� � ������ ��� ���

reduces wasteóall on a footprint of only six letter-sized pieces of paper.

Eppendorf

�14���1#�$%%�!&'�(%'%

www.eppendorf.com/ngs-compact

Microbioreactor System

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selection, media and feed optimization, and early process development

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����33���34�����413��3���� �����/0�* (��14���4� ��3�14��41����1��

T cells, induced pluripotent stem cells, and other immune-derived cell

�3�����3����4� 13��3 3��1��1����43��� ��3�������13��3�4� �3�3��

�41���3������ ��3�����43�� �3���� ����4���3�������� ������14�����34��

more consistent cell-line screening and ranking. Adaptation of cell lines to

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��41��143��14�������3��� ��43�������3���3������4������3��3 ��4���

functionality. New media-mixing steps automate the creation of media

� 3����3 ����������3�33���1��43��������������3�����43�����34414���

Sartorius Stedim Biotech

�/2����/��+"��'!(�##%�$! �!

www.sartorius.com

LC/MS and GC/MS Sample Preparation

Together with sister company J.G. Finneran Associates, Porvair Sciences

/012� ���� ���1��1�1���/��/�����/� ���1��� ��� ���1 �����/21��

and microplates to enhance liquid and gas chromatography (LC/GC)

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���1��21� 2 ��/�� ���1���� �/ ���12� 21� � �� ��1��/��������� ���

save time. The highly acclaimed P3 (Protein Precipitation Plate) sets the

� �� 2���/2�1-��1����� ���1�/�/��� ����21�/������2/�1����2/����/�/��-

cal samples that can interfere with downstream LC/MS and GC/MS ap-

���� ��/����/2�/�12�&!��1 2���/2� �2����1��1.�,��2/��1�����1�����*��� �1�

� �1��11���1��������1��������21 1���1���2/�����/����1�2�,�� � ��1�

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�2/���1� �� ���1�����12��� �1��� ���� ���/���� �����/��1�/���/��1���/��

plates with the option of a dedicated sample concentrator. In independ-

1����/�� 2 ���1��1�������/2� �2����1��1.��11���1����� �1�� �1��11��

repeatedly shown to contain near-zero contaminants, ensuring protection

against leaching and interference with your LC/MS or GC/MS analyses.

Porvair Sciences

�/2����/�� !!�##&�$���

www.microplates.com/resources/porvair-chromatography-catalogue

High-Yield Protein Production in CHO Cells

�� �'$������!�&������'&�$�����&���'$����'���$�$%&'� �' ����

�& ���$'��&�&�$������'$�&���� &����$��&' �&����������� �����&��$��

�&������&����������&'��� ��&��&&�� ���$��&'��$��&'�� ���� � �� ��&��' �-

�&���&��'&�$����&����' ��&����&�&�&��'&�$��� ��&&��� ������

�$�� '���� � ��& ���$'��'$������ ����$��&� ���$��&'�'&�$���� ���

�'$�&������� �� �� ���&����"���&��&� ����$'�'&�$���� ����'$�&������

drug discovery continues to grow, and with the majority of therapeutic

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�� ��&&���$'� �� ���'&�� ��&�� ���'$����' ��&���&��'&�$���� ��$'���

CHOgro High Yield Expression System consists of CHOgro Expression

Medium, L-glutamine and poloxamer 188 medium supplements, CHOgro

Complex Formation Solution, TransIT-PRO Transfection Reagent, and

�� �'$����&'���� ��&'�������$���� ��$���'& ����&���&��'$�&���&�-

�'&�$���'$�&#����� ����$������&'�� ���&� ���&�&�����&�&��� ���

Mirus Bio

For info: 888-530-0801

������+����)�)�

Automated Colony Counting System

'��)�&���+)������)�����������*�+��*������*�������� )�����+)��) )-

gists to load plates and count colonies on up to 100 plates in

30 minóideal for improving throughput and accuracy in highly regulated

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*��+)�*�� ��)��)+����(�� ����)�+) � �������)��+�*��*���������

water analysis.

Synbiosis

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Page 7: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

CALL FOR NOMINATIONS

3 AWARDS

1 international senior award - € 150,0002 international junior awards - € 50,000 each

A distinguished international Jury will choose the Awardees:Dr. Elizabeth H. Blackburn, Prof. Pascale Cossart, Prof. Catherine Dulac, Dr. Yasmine Belkaïd, Prof. Alain Fischer,Prof. Jörg H. Hacker, Prof. Jules A. Hoffmann, Prof.Antonio Lanzavecchia, Dr Gary J. Nabel, Prof. Staffan Normark,Prof.Michel C.Nussenzweig, Prof.Anne O’Garra, Prof. Jeffrey V. Ravetch, Prof. Philippe Sansonetti.

Scientific Coordinator of Awards: Prof. Pascale Cossart

SPECIAL FOCUS FOR GLOBAL HEALTH

1 - IMMUNOLOGY

2 - MICROBIOLOGY & INFECTION

Awards Ceremony: Thursday, 12th December, 2019

DEADLINE FOR APPLICATION: JUNE, 25th

MORE INFORMATION ON:www.sanofi-institutpasteur-awards.com

TO APPLY:https://www.sanofi-institutpasteur-awards.org

CONTACT:[email protected]

Page 8: Angkor Wat - Science · Angkor Wat & Bintan Island “Ringof Fire” December18-27,2019 Where Science Gets Social. AAAS’Member Community is a one-stop destination for scientists

ARTIFICIAL INTELLIGENCE AUTONOMOUS VEHICLES BIOMATERIALS IN ROBOTICS HUMANOIDS LAND & UNDERSEA ROBOTS MEDICAL & SURGICAL ROBOTS

MICRO/NANO ROBOTS ROBOT ENGINEERING ROBOTS IN EDUCATION SPACE ROBOTS THEORETICAL ADVANCES WITH POSSIBLE APPLICATIONS

Transforming the Future

of Robotics

As amultidisciplinary online-only journal, Science Robotics publishes original,peer-reviewed,

research articles that advance the feld of robotics.The journal provides a central forum for

communication of new ideas, general principles, and original developments in research and

applications of robotics for all environments.

Learnmore at: ScienceRobotics.org