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Amber KunkelAdvisor: Jessica Wagenseil, D.Sc.Department of Biomedical EngineeringSaint Louis UniversityThe Feasibility of Using Stored Mouse Blood Vessels for Mechanical TestingWhat Are Blood Vessel Mechanics?How longitudinal force, diameter, compliance respond to inflation and longitudinal stretchingUnloaded dimensions Opening angle (residual strain)Stress and strain in response to stretches or inflations

Radial cutOpening angle (OA)Why Blood Vessel Mechanics?Model in vivo conditionsUnderstand normal functions and any abnormalitiesMechanics of mouse aorta and carotid used to study:Elastin +/- mice and Supravalvular Aortic Stenosis (Wagenseil lab)SmokingAortic developmentMuscular dystrophy and Marfan syndrome

Why Storage?Vessels usually tested within 1 day of dissectionBut the carotid and aorta are large elastic arteries, could theoretically be stored longerApplications of longer storage time:Improved collaborationEasier schedulingInsurance against equipment failure or other unexpected circumstancesStudy Overview30 mice (8 week old) sacrificed over 1 monthAscending aorta, left common carotid, and right common carotid removedFive time points: refrigerated in physiologic saline for 1, 3, 7, 14, or 28 days

Mechanical TestingSetupPreconditioningVessel BathPressure ControlledPump ForceTransducerMicroscope PressureTransducerDesktopComputer Translation StageLDzdStretchInflateMechanical Testing Ctd.Inflation protocolsAt 1, 1.1, and 1.2x in vivo length3 cycles, 0-175 mmHg, steps of 25, 12 sec/stepStretch protocolsAt 50, 100, and 150 mmHg3 cycles, 1-1.2x in vivo length

DimensionsThree rings cut from left carotid and ascending aortaImage under microscopeMeasure inner diameter, outer diameter, thicknessAscending aortas cut radially, used for opening angle measurements

Data Analysis Pressure-force, pressure-diameter, and pressure-compliance curves from 1 cycle of first inflation protocolImage J to compute thickness, inner and outer diametersCircumferential stretch, circ stress, and axial stressMatlab for opening angleANOVA and Scheffe post hoc test (P 3SD from mean and are not included in means or statistics for any of the dataPressurePressure0.00E+002.50E+015.00E+017.50E+011.00E+021.25E+021.50E+021.75E+020.00E+002.50E+015.00E+017.50E+011.00E+021.25E+021.50E+021.75E+02NameDateDays StoredVesselDiameterdifference b/w max and minForcediff b/w max and minCompliance (%)1day 20090609 lcc1200906091lcc13.76E+024.16E+024.61E+025.28E+025.97E+026.34E+026.56E+026.64E+022.88E+021.24E+001.03E+007.50E-013.60E-01-5.00E-01-1.07E+00-1.94E+00-2.78E+00-4.02E+001.06E+012.15E+012.54E+012.76E+011.93E+019.67E+004.69E+001.22E+001day 20090609 lcc21lcc23.68E+023.86E+024.50E+025.20E+026.10E+026.69E+026.82E+026.90E+023.22E+023.94E+003.91E+003.61E+003.26E+002.59E+002.37E+002.37E+002.37E+00-1.57E+004.89E+002.15E+013.21E+013.29E+012.70E+011.16E+013.12E+001.17E+001day 20090609 lcc31lcc34.18E+024.50E+025.04E+025.62E+026.82E+027.38E+027.57E+027.65E+023.47E+022.97E+002.91E+002.61E+002.21E+001.22E+005.20E-017.00E-02-3.90E-01-3.36E+007.66E+001.97E+012.35E+013.29E+012.96E+011.08E+013.63E+001.06E+001day 20090611 lcc1200906111lcc13.46E+023.73E+024.29E+025.01E+026.00E+026.50E+026.61E+026.72E+023.26E+023.75E+003.67E+003.49E+003.15E+002.40E+001.76E+001.28E+009.60E-01-2.79E+007.80E+002.28E+013.18E+013.65E+012.81E+011.00E+013.36E+001.66E+001day 20090611 lcc21lcc23.97E+023.94E+024.50E+025.70E+026.69E+026.90E+026.93E+026.96E+022.99E+022.34E+002.25E+002.08E+001.41E+005.30E-01-2.70E-01-7.00E-01-1.12E+00-3.46E+00-7.56E-011.35E+014.09E+014.40E+012.05E+013.57E+008.68E-014.33E-011day 20090611 lcc31lcc33.49E+023.76E+024.24E+024.64E+025.25E+026.10E+026.34E+026.53E+023.04E+02-1.30E-01-2.70E-01-5.00E-01-8.10E-01-1.46E+00-2.05E+00-2.67E+00-2.95E+00-2.82E+007.74E+002.05E+012.22E+012.26E+012.93E+012.01E+016.93E+003.00E+00One Day Average3.67E+023.89E+024.43E+025.17E+026.00E+026.51E+026.65E+026.75E+023.08E+020.00E+002.23E+002.12E+001.89E+001.47E+007.12E-011.48E-01-3.32E-01-7.04E-01-2.93E+006.33E+001.99E+012.93E+013.27E+012.56E+011.10E+013.77E+001.42E+00One Day St Dev2.09E+011.72E+011.56E+013.87E+015.12E+013.09E+012.31E+011.79E+011.59E+010.00E+001.72E+001.77E+001.77E+001.76E+001.77E+001.87E+002.13E+002.33E+009.15E-013.91775286983.32643270027.04161871897.37146711714.55740293175.32079341091.99400084580.86642139743day 20090612 lcc1200906123lcc13.78E+024.05E+024.53E+025.14E+025.84E+026.26E+026.37E+026.45E+022.67E+021.15E+001.08E+007.50E-012.20E-01-5.00E-01-1.18E+00-1.41E+00-1.75E+00-2.90E+007.14E+001.90E+012.53E+012.71E+012.08E+018.95E+003.01E+001.26E+003day 20090612 lcc23lcc23.97E+024.18E+024.61E+025.25E+026.05E+026.37E+026.48E+026.53E+022.56E+021.34E+001.22E+009.10E-014.20E-01-4.80E-01-9.40E-01-1.27E+00-1.71E+00-3.05E+005.29E+001.56E+012.42E+012.91E+012.05E+017.02E+002.50E+007.72E-013day 20090612 lcc33lcc33.86E+024.10E+024.48E+025.01E+025.78E+026.66E+027.04E+027.17E+023.31E+021.81E+001.66E+001.36E+009.30E-011.80E-01-7.00E-01-1.15E+00-1.47E+00-3.28E+006.22E+001.55E+012.11E+012.72E+013.06E+012.09E+017.55E+001.85E+003day 20090625 lcc4200906253lcc43.41E+023.86E+024.29E+025.04E+025.54E+025.89E+026.05E+026.16E+022.75E+021.45E+001.36E+001.21E+007.70E-013.60E-01-1.80E-01-5.30E-01-9.00E-01-2.35E+001.32E+012.43E+012.86E+012.74E+011.62E+019.03E+004.53E+001.82E+003day 20090625 lcc53lcc53.89E+024.21E+024.61E+025.12E+025.52E+025.78E+025.94E+026.08E+022.19E+02-1.60E-01-1.60E-01-4.30E-01-7.20E-01-1.08E+00-1.42E+00-1.71E+00-2.02E+00-1.86E+008.23E+001.77E+012.06E+011.89E+011.25E+017.48E+005.13E+002.36E+003day 20090625 lcc63lcc64.02E+024.34E+024.82E+025.54E+026.21E+026.53E+026.64E+026.72E+022.70E+027.00E-02-6.00E-02-2.60E-01-7.30E-01-1.48E+00-2.03E+00-2.46E+00-2.88E+00-2.95E+007.96E+001.90E+012.60E+012.70E+011.72E+016.84E+002.89E+001.20E+00Three Day Average3.82E+024.12E+024.56E+025.18E+025.82E+026.25E+026.42E+026.52E+022.70E+029.43E-018.50E-015.90E-011.48E-01-5.00E-01-1.08E+00-1.42E+00-1.79E+00-2.73E+008.01E+001.85E+012.43E+012.61E+011.97E+011.00E+014.27E+001.54E+00Three Day St Dev21.84872231216.305418322317.477604717719.397594352627.39829678434.970940317240.154700845639.76640122853.62E+010.79849024210.76866117370.75739025610.72137137920.7069936350.6327637790.64082498910.65474931595.26E-012.76815648653.24968399593.06017383853.63491887586.16611707945.41792937221.90783035150.569592357614day 20090625 lcc12009062514lcc13.97E+024.26E+024.72E+025.22E+025.65E+025.92E+026.02E+026.10E+022.13E+027.10E-016.90E-013.70E-01-6.00E-02-4.00E-01-8.30E-01-1.17E+00-1.63E+00-2.34E+007.30E+001.81E+012.14E+011.88E+011.30E+016.47E+003.02E+001.33E+0014day 20090625 lcc214lcc24.08E+024.24E+024.66E+025.09E+025.60E+025.89E+026.18E+026.32E+022.24E+02-7.00E-02-1.70E-01-5.20E-01-8.70E-01-1.55E+00-2.06E+00-2.68E+00-2.99E+00-2.92E+003.92E+001.38E+011.91E+011.92E+011.52E+011.01E+017.19E+002.27E+0014day 20090625 lcc314lcc34.05E+024.34E+024.72E+025.41E+025.92E+026.24E+026.40E+026.50E+022.45E+021.70E-016.00E-02-2.00E-01-7.00E-01-1.26E+00-1.76E+00-2.20E+00-2.60E+00-2.77E+007.16E+001.59E+012.34E+012.40E+011.48E+017.97E+004.13E+001.56E+0014day 20090626 lcc12009062614lcc14.00E+024.24E+024.58E+025.04E+025.60E+026.16E+026.42E+026.53E+022.53E+02-2.80E-01-4.70E-01-7.30E-01-1.10E+00-1.56E+00-2.14E+00-2.38E+00-2.70E+00-2.42E+006.00E+001.40E+011.81E+012.12E+012.11E+011.42E+015.93E+001.71E+0014day 20090626 lcc214lcc24.08E+024.37E+024.88E+025.36E+025.94E+026.40E+026.58E+026.72E+022.64E+02-1.09E+00-1.24E+00-1.51E+00-1.90E+00-2.47E+00-3.14E+00-3.61E+00-4.03E+00-2.94E+007.11E+001.88E+012.15E+012.07E+011.86E+011.06E+014.94E+002.13E+00Fourteen Day Average4.04E+024.29E+024.71E+025.22E+025.74E+026.12E+026.32E+026.43E+022.40E+02-1.12E-01-2.26E-01-5.18E-01-9.26E-01-1.45E+00-1.99E+00-2.41E+00-2.79E+00-2.68E+006.30E+001.61E+012.07E+012.08E+011.65E+019.86E+005.04E+001.80E+00Fourteen Day St Dev4.92950301756.082762530311.009087155616.195678435917.297398648421.63792966072223.44781439712.09E+010.65986362230.70917557770.69258212510.6676675820.74180186030.82890288940.87969881210.86130714612.81E-011.42737390092.27548325062.10309344112.05966863733.24531548812.94279663511.60856969630.3904386773frozen 20090629 lcc32009062914 frozenlcc34.50E+024.66E+025.04E+025.52E+026.02E+026.34E+026.45E+026.53E+022.03E+022.20E-011.40E-01-1.50E-01-6.10E-01-1.38E+00-2.15E+00-2.68E+00-3.15E+00-3.37E+003.56E+001.17E+011.77E+011.86E+011.44E+017.05E+002.98E+001.24E+00frozen 20090630 lcc12009063014 frozenlcc14.00E+024.24E+024.66E+025.25E+025.94E+026.34E+026.53E+026.61E+022.61E+029.50E-017.60E-013.80E-01-6.00E-02-6.60E-01-1.20E+00-1.62E+00-2.08E+00-3.03E+006.00E+001.59E+012.26E+012.58E+011.99E+019.73E+004.22E+001.23E+00frozen 20090630 lcc3lcc3 (may have already had hole at this point?)4.16E+024.42E+024.90E+025.46E+025.94E+026.21E+026.32E+026.37E+022.21E+02-6.00E-02-1.60E-01-4.70E-01-8.50E-01-1.10E+00-1.65E+00-1.95E+00-2.17E+00-2.11E+006.25E+001.71E+012.23E+012.02E+011.33E+016.32E+002.56E+007.91E-01Frozen Averages4.22E+024.44E+024.87E+025.41E+025.97E+026.30E+026.43E+026.50E+022.28E+023.70E-012.47E-01-8.00E-02-5.07E-01-1.05E+00-1.67E+00-2.08E+00-2.47E+00-2.84E+005.27E+001.49E+012.08E+012.15E+011.59E+017.70E+003.25E+001.09E+00Frozen St Dev25.534290669621.071307505719.218047073914.17744687884.61880215357.505553499510.598742063712.22020185322.97E+010.5214403130.46918368830.42930175870.40501028790.3629508690.47521924760.54243279150.5934924886.52E-011.48872649752.83458475262.74544384293.78642134293.51509844311.79712370940.86394746460.25505560487day 20090630 lcc4200906307lcc44.34E+024.56E+025.01E+025.76E+026.34E+026.74E+026.88E+026.98E+022.64E+025.10E-013.90E-014.00E-02-4.20E-01-9.20E-01-1.36E+00-1.71E+00-1.97E+00-2.48E+005.07E+001.49E+012.48E+012.50E+011.64E+018.39E+003.53E+001.45E+007day 20090630 lcc57lcc53.89E+024.16E+024.69E+025.44E+026.18E+026.56E+026.66E+026.72E+022.83E+021.18E+001.13E+009.40E-014.30E-01-1.50E-01-7.60E-01-1.10E+00-1.37E+00-2.55E+006.94E+001.97E+012.87E+012.96E+011.98E+017.67E+002.43E+009.01E-017day 20090701 lcc1200907017lcc14.05E+024.69E+025.06E+025.89E+026.69E+027.14E+027.09E+027.12E+023.07E+021.15E+008.80E-017.10E-011.70E-01-6.80E-01-1.62E+00-2.24E+00-2.77E+00-3.92E+001.58E+012.37E+012.43E+013.00E+012.03E+016.03E+00-2.77E-014.23E-017day 20090701 lcc27lcc24.29E+024.50E+024.88E+025.41E+025.92E+026.16E+026.32E+026.40E+022.11E+024.30E-013.00E-011.30E-01-2.80E-01-7.70E-01-1.16E+00-1.51E+00-1.85E+00-2.28E+004.90E+001.33E+011.93E+012.03E+011.35E+016.65E+003.86E+001.27E+007day 20090701 lcc37lcc34.26E+024.32E+024.85E+025.68E+026.58E+027.04E+027.12E+027.14E+022.88E+021.07E+001.02E+007.70E-011.30E-01-7.90E-01-1.59E+00-2.11E+00-2.66E+00-3.73E+001.41E+001.37E+012.94E+013.30E+012.28E+018.13E+001.42E+002.81E-01Seven Day Average4.17E+024.45E+024.90E+025.64E+026.34E+026.73E+026.81E+026.87E+022.71E+028.68E-017.44E-015.18E-016.00E-03-6.62E-01-1.30E+00-1.73E+00-2.12E+00-2.99E+006.82E+001.71E+012.53E+012.76E+011.86E+017.37E+002.19E+008.65E-01Seven Day St Dev18.981570008820.803845798314.549914089120.695410119230.906310035339.30903204133.238531856931.26019833593.67E+010.36663333180.37620473150.40542570220.34832456130.29878085610.35400564970.46100976130.58564494367.70E-015.40266052954.489999084.04989273254.95995544813.65090577751.00254332891.68347036390.511050000928day 20090702 lcc12009070228lcc14.05E+024.29E+024.66E+025.14E+025.60E+025.92E+026.13E+026.24E+022.19E+021.53E+001.37E+009.50E-014.70E-01-1.00E-01-7.20E-01-1.29E+00-1.70E+00-3.23E+005.93E+001.46E+011.89E+011.92E+011.47E+019.26E+005.34E+001.79E+0028day 20090702 lcc228lcc24.32E+024.50E+024.98E+025.44E+026.00E+026.32E+026.50E+026.61E+022.29E+023.10E+002.95E+002.65E+002.27E+001.74E+001.21E+008.20E-015.10E-01-2.59E+00*4.17E+001.48E+011.99E+011.95E+011.56E+018.18E+004.54E+001.69E+0031day 20090706 lcc12009070631lcc14.05E+024.44E+024.92E+025.55E+026.32E+026.64E+026.80E+026.93E+022.88E+021.17E+009.70E-017.20E-013.00E-01-5.30E-01-1.28E+00-1.90E+00-2.11E+00-3.28E+009.63E+002.04E+012.36E+012.67E+011.89E+017.47E+004.32E+001.91E+0031day 20090706 lcc231lcc23.64E+024.18E+024.47E+025.01E+025.49E+025.84E+026.10E+026.26E+022.62E+028.60E-016.60E-014.30E-01-3.00E-02-6.20E-01-1.25E+00-1.91E+00-2.38E+00-3.24E+001.48E+012.18E+011.90E+012.17E+011.60E+011.08E+017.08E+002.62E+0031day 20090706 lcc331lcc33.54E+024.08E+024.60E+025.20E+025.75E+025.97E+026.10E+026.13E+022.59E+021.64E+001.38E+001.12E+006.60E-011.90E-01-3.50E-01-6.40E-01-9.90E-01-2.63E+001.53E+012.80E+012.58E+012.36E+011.44E+016.00E+002.67E+004.92E-011 Month Average3.92E+024.30E+024.73E+025.27E+025.83E+026.14E+026.33E+026.43E+022.51E+021.66E+001.47E+001.17E+007.34E-011.36E-01-4.78E-01-9.84E-01-1.33E+00-2.99E+009.96E+001.99E+012.15E+012.21E+011.59E+018.35E+004.79E+001.70E+001 Month St Dev32.272279126217.498571370321.674870241822.174309459433.31215994233.529091845731.445190411333.06508732792.77E+010.86182944950.8824001360.86477164620.8953379250.95479317131.02023036611.13610298831.15638661363.51E-015.04335609835.56067112983.09001130793.08950351111.80760073731.82146750171.60504525090.7689875143w/o 7/2 lcc21.54E+001.42E+001.18E+008.47E-013.52E-01-1.09E-01-4.77E-01-6.79E-01*these are all around the same (-3) as they should be1.14708011021.10081197081.00421743720.95130509770.98515719981.11035988631.32261975731.42632969040-2525-5050-7575-100100-125125-150150-175Step1234567Step12345671 daydiam change2.18E+015.38E+017.38E+018.36E+015.04E+011.46E+019.80E+001force change-1.10E-01-2.32E-01-4.12E-01-7.62E-01-5.64E-01-4.80E-01-3.72E-013 day3.02E+014.33E+016.27E+016.40E+014.25E+011.72E+019.83E+003-9.33E-02-2.60E-01-4.42E-01-6.48E-01-5.75E-01-3.47E-01-3.67E-017 day2.80E+014.52E+017.38E+017.06E+013.86E+018.60E+005.80E+007-1.24E-01-2.26E-01-5.12E-01-6.68E-01-6.36E-01-4.36E-01-3.90E-0114 day2.54E+014.22E+015.12E+015.18E+013.80E+011.98E+011.14E+0114-1.14E-01-2.92E-01-4.08E-01-5.22E-01-5.38E-01-4.22E-01-3.82E-0128 day3.78E+014.28E+015.42E+015.64E+013.06E+011.88E+011.08E+0128(w/o 7/2 lcc2)-1.25E-01-2.35E-01-3.34E-01-4.95E-01-4.61E-01-3.68E-01-2.01E-01Frozen2.20E+014.27E+015.43E+015.57E+013.30E+011.37E+017.00E+00frozen-1.23E-01-3.27E-01-4.27E-01-5.40E-01-6.20E-01-4.17E-01-3.83E-01what is happening to the 1day b/w 75 and 100? Is that normal?Avg Diam ChangeDiam Change St Dev1 day3.13E+022.27E+013 day2.70E+023.62E+017 day2.71E+023.67E+0114 day2.40E+022.09E+0128 day2.51E+022.77E+01frozen2.28E+022.97E+01

comp_summ

1day 20090609 lcc11day 20090609 lcc21day 20090609 lcc31day 20090611 lcc11day 20090611 lcc21day 20090611 lcc33day 20090612 lcc13day 20090612 lcc23day 20090612 lcc33day 20090625 lcc43day 20090625 lcc53day 20090625 lcc614 day 20090625 lcc114 day 20090625 lcc214day 20090625 lcc314 day 20090626 lcc114 day 20090626 lcc2frozen 20090629 lcc3frozen 20090630 lcc1frozen 20090630 lcc37day 20090630 lcc47day 20090630 lcc57day 20090701 lcc17day 20090701 lcc27day 20090701 lcc328day 20090702 lcc128day 20090702 lcc231day 20090706 lcc131day 20090706 lcc231day 20090706 lcc3PressureDiameterpressure-diameter

stress etc

1day 20090609 lcc11day 20090609 lcc21day 20090609 lcc31day 20090611 lcc11day 20090611 lcc21day 20090611 lcc33day 20090612 lcc13day 20090612 lcc23day 20090612 lcc33day 20090625 lcc43day 20090625 lcc53day 20090625 lcc614day 20090625 lcc114day 20090625 lcc214day 20090625 lcc314day 20090626 lcc114day 20090626 lcc2frozen 20090629 lcc3frozen 20090630 lcc1frozen 20090630 lcc37day 20090630 lcc47day 20090630 lcc57day 20090701 lcc17day 20090701 lcc27day 20090701 lcc328day 20090702 lcc128day 20090702 lcc231day 20090706 lcc131day 20090706 lcc231day 20090706 lcc3pressureforcepressure-force

dim-pixels22.747893675422.747893675436.19760581436.19760581436.664696916836.664696916820.945166506920.945166506927.664056101727.664056101729.687258770929.6872587709

max-min diameter change

dim-um20.897368255420.897368255421.84872231221.8487223124.92950301754.929503017532.272279126232.272279126218.981570008818.981570008817.233687939617.233687939616.305418322316.30541832236.08276253036.082762530317.498571370317.498571370320.803845798320.803845798315.642889758615.642889758617.477604717717.477604717711.009087155611.009087155621.674870241821.674870241814.549914089114.549914089138.74016004138.74016004119.397594352619.397594352616.195678435916.195678435922.174309459422.174309459420.695410119220.695410119251.222065557751.222065557727.39829678427.39829678417.297398648417.297398648433.31215994233.31215994230.906310035330.906310035330.883652633730.883652633734.970940317234.970940317221.637929660721.637929660733.529091845733.529091845739.30903204139.30903204123.080294625523.080294625540.154700845640.1547008456222231.445190411331.445190411333.238531856933.238531856917.8885438217.8885438239.766401228539.766401228523.447814397123.447814397133.065087327933.065087327931.260198335931.2601983359

1 day3 day14 day7 day28 dayPressure (mmHg)Average Diameter (um)Average Diameter v. Pressure

dim_summ1.71728564891.71728564890.65986362230.79849024210.79849024210.65986362230.36663333180.36663333180.86182944950.86182944951.76944058961.76944058960.70917557770.76866117370.76866117370.70917557770.37620473150.37620473150.8824001360.8824001361.77243617661.77243617660.69258212510.75739025610.75739025610.69258212510.40542570220.40542570220.86477164620.86477164621.76497308761.76497308760.6676675820.72137137920.72137137920.6676675820.34832456130.34832456130.8953379250.8953379251.77453374161.77453374160.74180186030.7069936350.7069936350.74180186030.29878085610.29878085610.95479317130.95479317131.87251702261.87251702260.82890288940.6327637790.6327637790.82890288940.35400564970.35400564971.02023036611.02023036612.12642187722.12642187720.87969881210.64082498910.64082498910.87969881210.46100976130.46100976131.13610298831.13610298832.33161531992.33161531990.86130714610.65474931590.65474931590.86130714610.58564494360.58564494361.15638661361.1563866136

1 Day3 day14 day7 day28 dayPressure (mmHg)Average force (mN)Average Force v. Pressure

3.91775286983.91775286982.76815648652.76815648651.42737390091.42737390095.04335609835.04335609835.40266052955.40266052953.32643270023.32643270023.24968399593.24968399592.27548325062.27548325065.56067112985.56067112984.489999084.489999087.04161871897.04161871893.06017383853.06017383852.10309344112.10309344113.09001130793.09001130794.04989273254.04989273257.37146711717.37146711713.63491887583.63491887582.05966863732.05966863733.08950351113.08950351114.95995544814.95995544814.55740293174.55740293176.16611707946.16611707943.24531548813.24531548811.80760073731.80760073733.65090577753.65090577755.32079341095.32079341095.41792937225.41792937222.94279663512.94279663511.82146750171.82146750171.00254332891.00254332891.99400084581.99400084581.90783035151.90783035151.60856969631.60856969631.60504525091.60504525091.68347036391.68347036390.86642139740.86642139740.56959235760.56959235760.39043867730.39043867730.76898751430.76898751430.51105000090.5110500009

1 day3 day14 day7 day28 dayPressure (mmHg)ComplianceCompliance v Pressure

000000000000000000000000000000000000000000000000

one day compliance

PressurePressurePressure0.00E+002.50E+015.00E+017.50E+011.00E+021.25E+021.50E+021.75E+020.00E+002.50E+015.00E+017.50E+011.00E+021.25E+021.50E+021.75E+020.00E+002.50E+015.00E+017.50E+011.00E+021.25E+021.50E+021.75E+02Circ Stretch Ratio (1)Diff b/w final + initialCirc Stress (2)Axial Stress (4)NameDateDays StoredVesseldiffdiff1day 20090609 lcc1200906091lcc18.97E-011.06E+001.22E+001.49E+001.73E+001.86E+001.90E+001.93E+001.04E+001.51E+008.36E+002.17E+014.94E+019.02E+011.32E+021.65E+022.00E+021.99E+021.86E+011.80E+012.05E+012.66E+013.40E+014.16E+014.84E+015.49E+013.62E+011day 20090609 lcc21lcc28.69E-019.71E-011.17E+001.43E+001.73E+001.90E+001.95E+001.97E+001.10E+001.80E+007.75E+002.44E+015.43E+011.07E+021.63E+022.06E+022.45E+022.43E+026.38E+016.48E+016.83E+017.54E+019.16E+011.16E+021.37E+021.54E+029.05E+012.54223967912.50040721642.4971100482.24882993232.20254372642.6827776023.08987079353.46172352071day 20090609 lcc31lcc39.75E-011.10E+001.30E+001.56E+001.94E+002.14E+002.19E+002.21E+001.24E+001.37E+007.42E+002.06E+014.40E+019.33E+011.43E+021.81E+022.14E+022.13E+023.52E+013.67E+013.90E+014.47E+015.75E+017.31E+018.65E+019.70E+016.18E+011day 20090611 lcc1200906111lcc17.85E-018.96E-011.08E+001.36E+001.65E+001.78E+001.82E+001.85E+001.06E+001.64E+007.68E+002.40E+015.98E+011.20E+021.74E+022.16E+022.60E+022.58E+026.78E+016.88E+017.29E+018.20E+019.87E+011.13E+021.27E+021.42E+027.39E+012.78182208692.73162034932.75879100142.5674682932.49998327872.55510260852.68553542392.95185068741day 20090611 lcc21lcc28.64E-018.88E-011.09E+001.46E+001.76E+001.81E+001.82E+001.83E+009.64E-012.43E+006.18E+001.96E+015.56E+011.08E+021.45E+021.75E+022.03E+022.01E+023.26E+013.31E+013.53E+014.48E+015.75E+016.54E+017.33E+018.08E+014.82E+011day 20090611 lcc31lcc37.17E-018.28E-019.60E-011.10E+001.32E+001.52E+001.64E+001.68E+009.65E-011.11E+005.59E+001.54E+013.01E+016.08E+011.01E+021.43E+021.80E+021.78E+02-1.36E+00-1.25E+00-4.27E-011.45E+007.46E+001.82E+013.10E+014.23E+014.37E+01One Day Average8.51E-019.57E-011.14E+001.40E+001.69E+001.83E+001.89E+001.91E+001.06E+001.64E+007.16E+002.10E+014.88E+019.65E+011.43E+021.81E+022.17E+022.15E+023.61E+013.67E+013.93E+014.58E+015.78E+017.13E+018.37E+019.52E+015.91E+012.13E+012.16E+012.36E+012.94E+013.91E+014.96E+015.98E+016.87E+01One Day St Dev0.08980452930.10551203630.11945394660.16067732120.20382537430.19910593410.18118747680.1778949250.10174974050.45146974221.05315331993.310364279710.688546596320.575527984425.351754134426.643339253529.964611109629.858114770326.448667676726.904226234327.998653046330.082221054434.377778748938.765335948841.906559055745.387292337620.46051317916.742852857117.258050835217.893231964320.484479601323.818970763424.864618465124.86680799524.73042134563day 20090612 lcc1200906123lcc17.74E-019.02E-011.07E+001.28E+001.52E+001.66E+001.70E+001.72E+009.44E-019.34E-015.22E+001.60E+013.48E+016.66E+011.00E+021.26E+021.49E+021.48E+021.43E+011.48E+011.56E+011.84E+012.40E+013.26E+013.99E+014.74E+013.30E+013day 20090612 lcc23lcc28.61E-019.58E-011.11E+001.35E+001.59E+001.69E+001.72E+001.73E+008.72E-011.38E+006.19E+001.77E+014.08E+017.70E+011.08E+021.34E+021.60E+021.59E+021.73E+011.72E+011.87E+012.22E+012.84E+013.79E+014.56E+015.25E+013.52E+013day 20090612 lcc33lcc38.32E-019.21E-011.08E+001.25E+001.51E+001.76E+001.86E+001.90E+001.07E+001.38E+005.79E+001.96E+013.99E+017.98E+011.36E+021.84E+022.23E+022.22E+022.53E+012.51E+012.64E+012.93E+013.75E+015.42E+017.14E+018.61E+016.07E+013day 20090625 lcc4200906253lcc48.55E-011.05E+001.23E+001.51E+001.72E+001.83E+001.89E+001.93E+001.07E+001.37E+008.61E+002.20E+015.17E+018.89E+011.27E+021.63E+021.99E+021.97E+022.51E+012.68E+012.94E+013.68E+014.68E+015.61E+016.74E+017.79E+015.28E+013day 20090625 lcc53lcc59.08E-011.04E+001.20E+001.38E+001.52E+001.61E+001.66E+001.70E+007.96E-011.58E+007.31E+001.94E+014.04E+016.62E+019.19E+011.19E+021.46E+021.44E+02-1.55E+00-1.99E-011.97E+008.19E+001.55E+012.27E+013.16E+014.05E+014.20E+013day 20090625 lcc63lcc68.94E-011.04E+001.20E+001.43E+001.65E+001.74E+001.77E+001.79E+008.97E-011.71E+008.51E+002.11E+014.71E+018.74E+011.22E+021.50E+021.79E+021.78E+021.58E+002.16E+004.93E+001.15E+012.04E+012.99E+013.92E+014.71E+014.55E+01Three Day Average8.54E-019.85E-011.15E+001.37E+001.59E+001.71E+001.77E+001.80E+009.41E-011.39E+006.94E+001.93E+014.24E+017.76E+011.14E+021.46E+021.76E+021.75E+021.37E+011.43E+011.62E+012.11E+012.88E+013.89E+014.92E+015.86E+014.49E+01Three Day St Dev0.04809379630.06604700790.06680769980.09411503190.08169132760.07809301120.08972064230.09597903470.110090660.26273415751.43045300242.20028375915.98337174679.802348133216.888815907124.62427931630.392697164130.35046010211.46540169211.297807351111.070202563710.786313002211.571810667413.526882636416.337916955518.704803740210.552315189814day 20090625 lcc12009062514lcc18.67E-019.74E-011.14E+001.32E+001.46E+001.54E+001.57E+001.60E+007.30E-011.57E+007.21E+002.00E+014.06E+016.58E+019.17E+011.17E+021.40E+021.38E+029.74E+001.06E+011.38E+011.66E+012.37E+013.14E+013.71E+014.33E+013.36E+0114day 20090625 lcc214lcc29.80E-011.05E+001.20E+001.35E+001.51E+001.64E+001.73E+001.77E+007.91E-012.86E+007.46E+002.12E+014.00E+016.86E+011.01E+021.34E+021.63E+021.61E+021.87E-013.22E-012.38E+006.17E+001.02E+011.66E+012.58E+013.54E+013.52E+0114day 20090625 lcc314lcc39.09E-011.01E+001.15E+001.36E+001.54E+001.63E+001.68E+001.71E+008.03E-011.87E+008.15E+002.11E+014.59E+017.92E+011.11E+021.43E+021.75E+021.73E+023.03E+004.22E+006.22E+001.14E+011.92E+012.74E+013.71E+014.67E+014.37E+0114day 20090626 lcc12009062614lcc11.13E+001.23E+001.37E+001.56E+001.79E+002.00E+002.06E+002.11E+009.74E-012.93E+001.10E+012.66E+015.19E+019.16E+011.45E+021.84E+022.25E+022.22E+02-3.42E+00-2.54E+00-3.13E-015.13E+001.50E+013.25E+014.72E+016.14E+016.48E+0114day 20090626 lcc214lcc29.10E-011.04E+001.19E+001.36E+001.55E+001.71E+001.75E+001.79E+008.80E-011.81E+007.76E+002.11E+014.09E+017.12E+011.13E+021.41E+021.69E+021.68E+02-1.31E+01-1.26E+01-1.04E+01-5.79E+001.34E+001.21E+011.99E+012.83E+014.14E+01Fourteen Day Average9.60E-011.06E+001.21E+001.39E+001.57E+001.70E+001.76E+001.80E+008.36E-012.21E+008.32E+002.20E+014.39E+017.53E+011.12E+021.44E+021.74E+021.72E+02-7.14E-013.77E-032.34E+006.71E+001.39E+012.40E+013.34E+014.30E+014.37E+01Fourteen Day St Dev0.10526895020.10000259970.09429644490.09616851990.12927567460.17558809840.18339528120.18993333440.09394133370.63869248281.54270744612.62569651895.096320112810.392308473120.283090880924.696872223231.050679671130.62515347788.43967786578.60214642188.89179174728.36253953928.606005559.155559472810.671193558212.499103417912.5005977896frozen 20090629 lcc32009062914 frozenlcc31.14E+001.21E+001.33E+001.49E+001.63E+001.73E+001.77E+001.79E+006.46E-015.32E+001.36E+013.41E+016.69E+011.07E+021.53E+021.91E+022.26E+022.21E+026.05E+008.54E+001.22E+011.94E+012.62E+013.61E+014.39E+015.44E+014.84E+01frozen 20090630 lcc12009063014 frozenlcc19.32E-011.04E+001.18E+001.39E+001.59E+001.70E+001.74E+001.77E+008.35E-011.82E+009.68E+002.56E+015.66E+019.65E+011.39E+021.75E+022.13E+022.12E+021.54E+011.43E+011.60E+012.35E+013.25E+014.67E+015.70E+016.94E+015.40E+01frozen 20090630 lcc3lcc31.05E+001.14E+001.32E+001.50E+001.67E+001.74E+001.78E+001.80E+007.48E-012.80E+001.05E+012.98E+015.66E+019.50E+011.29E+021.63E+021.93E+021.90E+022.48E-011.61E+006.18E+001.27E+012.47E+013.48E+014.70E+015.65E+015.63E+01Frozen Averages1.04E+001.13E+001.28E+001.46E+001.63E+001.73E+001.76E+001.78E+007.43E-013.31E+001.13E+012.98E+016.00E+019.94E+011.40E+021.76E+022.11E+022.08E+027.22E+008.14E+001.14E+011.85E+012.78E+013.92E+014.93E+016.01E+015.29E+01Frozen St Dev1.06E-018.62E-028.25E-025.94E-024.05E-022.27E-021.96E-021.55E-020.09428395221.80E+002.08E+004.26E+005.96E+006.45E+001.20E+011.41E+011.67E+0115.69487828647.62E+006.34E+004.93E+005.41E+004.16E+006.52E+006.89E+008.10E+004.07117223367day 20090630 lcc4200906307lcc49.56E-011.04E+001.21E+001.46E+001.66E+001.78E+001.83E+001.86E+009.05E-011.61E+006.55E+001.84E+014.20E+017.10E+011.04E+021.33E+021.59E+021.57E+026.17E+006.46E+008.39E+001.46E+012.26E+013.29E+014.30E+015.25E+014.64E+017day 20090630 lcc57lcc59.47E-011.06E+001.24E+001.50E+001.69E+001.80E+001.83E+001.85E+009.02E-012.18E+001.18E+013.25E+017.44E+011.23E+021.80E+022.24E+022.63E+022.61E+022.23E+012.48E+013.09E+014.09E+015.52E+017.23E+018.70E+011.01E+027.88E+017day 20090701 lcc1200907017lcc11.01E+001.23E+001.40E+001.64E+001.91E+002.04E+002.03E+002.03E+001.02E+001.47E+001.32E+013.40E+017.10E+011.27E+021.88E+022.18E+022.51E+022.49E+021.86E+012.03E+012.53E+013.35E+014.78E+016.30E+016.84E+017.64E+015.78E+017day 20090701 lcc27lcc21.00E+001.07E+001.19E+001.34E+001.51E+001.58E+001.62E+001.64E+006.35E-013.31E+001.19E+013.01E+015.83E+019.87E+011.38E+021.72E+022.01E+021.98E+028.37E+009.43E+001.44E+012.12E+013.28E+014.44E+015.70E+016.53E+015.69E+017day 20090701 lcc37lcc31.02E+001.04E+001.22E+001.46E+001.75E+001.86E+001.88E+001.89E+008.68E-016.35E+001.14E+013.25E+017.05E+011.38E+021.94E+022.42E+022.75E+022.69E+022.10E+012.27E+012.70E+013.54E+015.11E+016.59E+017.98E+018.69E+016.59E+01Seven Day Average9.87E-011.09E+001.25E+001.48E+001.70E+001.81E+001.84E+001.85E+008.67E-012.98E+001.10E+012.95E+016.33E+011.12E+021.61E+021.98E+022.30E+022.27E+021.53E+011.67E+012.12E+012.91E+014.19E+015.57E+016.70E+017.64E+016.11E+01Seven Day St Dev0.03291803160.07910940830.08447092530.10545388170.14756533440.16384995330.14864045330.14138247620.14248836722.01583830852.5553090526.390022492913.351902947826.861870217138.457266971944.317182173548.579907001147.67020368077.47538124818.24010156759.434166256810.849256068513.720138568816.444360574117.614143418718.786638641112.054708881228day 20090702 lcc12009070228lcc11.03E+001.12E+001.23E+001.39E+001.55E+001.63E+001.69E+001.72E+006.96E-012.75E+001.40E+013.44E+016.60E+011.11E+021.54E+022.00E+022.44E+022.41E+023.09E+013.11E+013.41E+013.93E+014.91E+015.83E+017.06E+018.33E+015.23E+0128day 20090702 lcc228lcc21.06E+001.12E+001.26E+001.41E+001.57E+001.65E+001.70E+001.73E+006.72E-014.12E+001.60E+014.18E+018.18E+011.35E+021.87E+022.39E+022.90E+022.85E+026.49E+016.68E+017.27E+018.24E+019.73E+011.13E+021.31E+021.50E+028.46E+0131day 20090706 lcc12009070631lcc19.88E-011.09E+001.25E+001.46E+001.65E+001.75E+001.80E+001.83E+008.38E-012.87E-011.80E+014.72E+019.90E+011.68E+022.38E+023.03E+023.69E+023.69E+022.62E+013.05E+013.88E+015.30E+016.86E+018.40E+011.06E+021.31E+021.05E+0231day 20090706 lcc231lcc21.06E+001.23E+001.37E+001.55E+001.73E+001.86E+001.94E+002.00E+009.39E-012.28E-011.53E+013.69E+017.18E+011.21E+021.76E+022.30E+022.87E+022.87E+021.92E+012.14E+012.60E+013.28E+014.23E+015.41E+016.79E+018.49E+016.57E+0131day 20090706 lcc331lcc38.72E-011.05E+001.20E+001.41E+001.57E+001.64E+001.68E+001.70E+008.31E-019.78E-011.53E+013.83E+017.99E+011.32E+021.79E+022.25E+022.71E+022.70E+02w/o 3rd3.58E+013.69E+014.29E+015.20E+016.51E+017.91E+019.39E+011.08E+027.18E+011 Month Average1.00E+001.12E+001.26E+001.44E+001.61E+001.71E+001.76E+001.80E+007.95E-011.67E+001.57E+013.97E+017.97E+011.33E+021.87E+022.39E+022.92E+022.90E+022.71E+023.54E+013.73E+014.29E+015.19E+016.45E+017.77E+019.39E+011.11E+027.58E+011 Month St Dev0.07707890270.06667705380.06436232230.06383368220.07418747490.09707940520.11114389120.12273075430.11053605631.70608194861.43800291234.970734815212.53537290421.695553105431.211215353138.460707506746.843026320447.632411617821.257340880517.601889541817.359848899617.79521663919.064138595421.352505072423.612451032826.181475844828.919705534919.888206824612345670-2525-5050-7575-100100-125125-150150-175avg w/o 3rd2.02E+001.52E+013.79E+017.49E+011.25E+021.74E+022.24E+022.73E+02avg w/o 2nd2.80E+013.00E+013.54E+014.43E+015.63E+016.89E+018.46E+011.02E+02stepwise changes1day1.06E-011.81E-012.62E-012.88E-011.46E-015.25E-022.53E-02stdev w/o 3rd1.75514249060.83549373223.10848558867.351963344511.078287018514.075381793916.871976655221.0334356307stdev w/o 2nd7.08E+006.40E+007.26E+009.85E+001.26E+011.49E+011.85E+012.24E+013day1.31E-011.62E-012.19E-012.19E-011.27E-015.38E-022.94E-02how far 3rd is away-0.98710797093.32590436393.00589008173.28416864563.92764083724.56454208074.71508238934.5879518541how far 2nd is away5.21397619545.74912781775.12383158073.86955825853.24802702562.97974151952.50689348942.13288547947day1.03E-011.61E-012.29E-012.23E-011.08E-012.79E-021.46E-0214day1.00E-011.50E-011.80E-011.80E-011.31E-015.76E-023.62E-0228day1.25E-011.39E-011.80E-011.67E-019.49E-025.59E-023.31E-0212345671234567frozen8.88E-021.46E-011.86E-011.67E-019.83E-023.71E-022.00E-020-2525-5050-7575-100100-125125-150150-1750-2525-5050-7575-100100-125125-150150-175stepwise changes1day5.52E+001.38E+012.79E+014.77E+014.64E+013.81E+013.58E+01stepwise changes1day5.48E-012.59E+006.55E+001.20E+011.35E+011.25E+011.14E+013day5.55E+001.24E+012.31E+013.52E+013.67E+013.18E+013.00E+013day6.14E-011.87E+004.91E+007.70E+001.01E+011.03E+019.38E+007day7.98E+001.85E+013.38E+014.84E+014.92E+013.69E+013.19E+017day1.44E+004.48E+007.90E+001.28E+011.38E+011.13E+019.39E+0014day6.11E+001.37E+012.19E+013.14E+013.71E+013.16E+013.05E+0114day7.17E-012.34E+004.37E+007.16E+001.01E+019.42E+009.60E+0028day1.41E+012.27E+013.70E+014.97E+014.93E+014.97E+014.92E+0128day1.95E+005.46E+008.84E+001.20E+011.26E+011.57E+011.71E+01frozen7.94E+001.86E+013.02E+013.94E+014.06E+013.60E+013.51E+01frozen9.17E-013.31E+007.08E+009.27E+001.14E+011.01E+011.08E+01DateDays StoredVesselstretch where crossing200906091lcc11.1651lcc21.14I think?? This is one that didn't stretch all the way1lcc31.14Same problem as above not sure200906111lcc11.081lcc21.111lcc31.175One Day Average1.135One Day St Dev200906123lcc11.1453lcc21.133lcc31.135200906253lcc41.1453lcc51.143lcc61.13Three Day AverageThree Day St Dev2009062514lcc11.18??? Looks funky14lcc21.1914lcc31.1652009062614lcc11.1414lcc21.175Fourteen Day AverageFourteen Day St Dev2009062914 frozenlcc31.192009063014 frozenlcc11.145lcc3 *n/aFrozen AveragesFrozen St Dev200906307lcc41.137lcc51.115200907017lcc11.1857lcc21.127lcc31.15Seven Day Average1.14Seven Day St Dev2009070228lcc11.14528lcc21.1552009070631lcc11.1831lcc21.231lcc31.121 Month Average1 Month St Devcirc stretch diffcirc stress diffaxial stress diff1 day1.06E+002.15E+025.91E+013 day9.41E-011.75E+024.49E+01just out of curiosity but I don't think these are very useful7 day8.67E-012.27E+026.11E+0114 day8.36E-011.72E+024.37E+0128 day7.95E-012.71E+027.58E+01frozen7.43E-012.08E+025.29E+01circ stretch diff st devcirc stress stdevaxial stdev0.101749740529.858114770320.4605131790.1100906630.35046010210.55231518980.142488367230.625153477812.50059778960.093941333715.69487828644.07117223360.110536056347.670203680712.05470888120.024722549221.257340880519.8882068246

1day 20090609 lcc11day 20090609 lcc21day 20090609 lcc31day 20090611 lcc11day 20090611 lcc21day 20090611 lcc33day 20090612 lcc13day 20090612 lcc23day 20090612 lcc33day 20090625 lcc43day 20090625 lcc53day 20090625 lcc614day 20090625 lcc114day 20090625 lcc214day 20090625 lcc314day 20090626 lcc114day 20090626 lcc2frozen 20090629 lcc3frozen 20090630 lcc1frozen 20090630 lcc37day 20090630 lcc47day 20090630 lcc57day 20090701 lcc17day 20090701 lcc27day 20090701 lcc328day 20090702 lcc128day 20090702 lcc231day 20090706 lcc131day 20090706 lcc231day 20090706 lcc3pressurecirc stretch ratiocirc stretch ratio v pressure

1day 20090609 lcc11day 20090609 lcc21day 20090609 lcc31day 20090611 lcc11day 20090611 lcc21day 20090611 lcc33day 20090612 lcc13day 20090612 lcc23day 20090612 lcc33day 20090625 lcc43day 20090625 lcc53day 20090625 lcc614day 20090625 lcc114day 20090625 lcc214day 20090625 lcc314day 20090626 lcc114day 20090626 lcc2frozen 20090629 lcc3frozen 20090630 lcc1frozen 20090630 lcc37day 20090630 lcc47day 20090630 lcc57day 20090701 lcc17day 20090701 lcc27day 20090701 lcc328day 20090702 lcc128day 20090702 lcc231day 20090706 lcc131day 20090706 lcc231day 20090706 lcc3pressurecirc stresscirc stress v pressure

000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000

1day 20090609 lcc11day 20090609 lcc21day 20090609 lcc31day 20090611 lcc11day 20090611 lcc21day 20090611 lcc33day 20090612 lcc13day 20090612 lcc23day 20090612 lcc33day 20090625 lcc43day 20090625 lcc53day 20090625 lcc614day 20090625 lcc114day 20090625 lcc214day 20090625 lcc314day 20090626 lcc114day 20090626 lcc2frozen 20090629 lcc3frozen 20090630 lcc1frozen 20090630 lcc37day 20090630 lcc47day 20090630 lcc57day 20090701 lcc17day 20090701 lcc27day 20090701 lcc328day 20090702 lcc128day 20090702 lcc231day 20090706 lcc131day 20090706 lcc231day 20090706 lcc3pressureaxial stressaxial stress v pressure

29.858114770329.858114770330.35046010230.35046010230.625153477830.625153477815.694878286415.694878286447.670203680747.670203680721.257340880521.2573408805

max-min diff in circ stress w/o 7/6 lcc1

20.46051317920.46051317910.552315189810.552315189812.500597789612.50059778964.07117223364.071172233612.054708881212.054708881219.888206824619.8882068246

max-min diff in axial stress

0.45146974220.45146974220.26273415750.26273415752.01583830852.01583830850.63869248280.63869248281.80373355641.80373355641.70608194861.70608194861.05315331991.05315331991.43045300241.43045300242.5553090522.5553090521.54270744611.54270744612.08216750672.08216750671.43800291231.43800291233.31036427973.31036427972.20028375912.20028375916.39002249296.39002249292.62569651892.62569651894.25555265434.25555265434.97073481524.970734815210.688546596310.68854659635.98337174675.983371746713.351902947813.35190294785.09632011285.09632011285.95935589115.959355891112.53537290412.53537290420.575527984420.57552798449.80234813329.802348133226.861870217126.861870217110.392308473110.39230847316.45050361536.450503615321.695553105421.695553105425.351754134425.351754134416.888815907116.888815907138.457266971938.457266971920.283090880920.283090880912.024213990312.024213990331.211215353131.211215353126.643339253526.643339253524.62427931624.62427931644.317182173544.317182173524.696872223224.696872223214.052407791914.052407791938.460707506738.460707506729.964611109629.964611109630.392697164130.392697164148.579907001148.579907001131.050679671131.050679671116.719282938416.719282938446.843026320446.8430263204

1 day3 day7 day14 day14 day (frozen)1 monthpressure (mmHg)circ stresscirc stress v pressure (excl 7/6 lcc1)

0.08980452930.08980452930.04809379630.04809379630.03291803160.03291803160.10557712080.10557712080.10526895020.10526895020.07707890270.07707890270.10551203630.10551203630.06604700790.06604700790.07910940830.07910940830.0861935630.0861935630.10000259970.10000259970.06667705380.06667705380.11945394660.11945394660.06680769980.06680769980.08447092530.08447092530.08254106760.08254106760.09429644490.09429644490.06436232230.06436232230.16067732120.16067732120.09411503190.09411503190.10545388170.10545388170.05940449740.05940449740.09616851990.09616851990.06383368220.06383368220.20382537430.20382537430.08169132760.08169132760.14756533440.14756533440.04047886560.04047886560.12927567460.12927567460.07418747490.07418747490.19910593410.19910593410.07809301120.07809301120.16384995330.16384995330.02270748570.02270748570.17558809840.17558809840.09707940520.09707940520.18118747680.18118747680.08972064230.08972064230.14864045330.14864045330.01961719260.01961719260.18339528120.18339528120.11114389120.11114389120.1778949250.1778949250.09597903470.09597903470.14138247620.14138247620.0154813870.0154813870.18993333440.18993333440.12273075430.1227307543

1 day3 day7 day14 day14 day (frozen)1 monthpressure (mmHg)circ stretch ratiocirc stretch ratio v. pressure

0000026.448667676726.448667676711.46540169211.4654016927.47538124817.47538124818.43967786578.43967786577.62258764717.622587647107.07644911827.07644911820000026.904226234326.904226234311.297807351111.29780735118.24010156758.24010156758.60214642188.60214642186.33613399326.336133993206.39871040736.39871040730000027.998653046327.998653046311.070202563711.07020256379.43416625689.43416625688.89179174728.89179174724.93340573024.933405730207.26442485747.26442485740000030.082221054430.082221054410.786313002210.786313002210.849256068510.84925606858.36253953928.36253953925.40562704595.405627045909.85164809619.85164809610000034.377778748934.377778748911.571810667411.571810667413.720138568813.72013856888.606005558.606005554.15734155114.1573415511012.626142401612.62614240160000038.765335948838.765335948813.526882636413.526882636416.444360574116.44436057419.15555947289.15555947286.52390213696.5239021369014.857440724414.85744072440000041.906559055741.906559055716.337916955516.337916955517.614143418717.614143418710.671193558210.67119355826.89067053386.8906705338018.481232627518.48123262750000045.387292337645.387292337618.704803740218.704803740218.786638641118.786638641112.499103417912.49910341798.09949570748.0994957074022.447125836522.4471258365

1 day3 day7 day14 day14 day (frozen)1 monthpressure (mmHg)axial stressaxial stress v. pressure (exc 7/2 lcc2)

0.10174974050.10174974050.110090660.110090660.14248836720.14248836720.09394133370.09394133370.11053605630.11053605630.02472254920.0247225492

max-min change in circ stretch

1day3day7day14day28dayfrozenstepchange in stretch ratiochange in circ stretch ratio b/w pressures

1day3day7day14day28dayfrozenstepwise changes in circ stress excl 7/6 lcc1

000000000000000000000000000000000000000000

1day3day7day14day28dayfrozenstepwise changes in axial stress excl 7/2 lcc2

000000000000000000000000000000000000000000000000

1 day3 day7 day14 day28 dayfrozencirc stretch ratiocirc stresscirc stress v circ stretch ratio

000000000000000000000000000000000000000000000000

1day3day7day14day28datfrozenlong stress v circ stretch ratio

Vessel StorageComplianceSacrifice DateTest DateTime (days)Mouse #VesselRingOuterInnerODIDThicknessVesselRingOuterInnerODIDThicknessVesselOAMajorMinorMajorMinorMajorMinorMajorMinor6/8/096/9/0911LCC1392.78260.817239.581156.361326.7985197.97164.41375ASC1541.988358.014473.386247.837450.001360.611544.69475ASC1156.02012443.763312.73306.416166.319378.2465236.367570.93952536.393339.865442.133230.871438.129336.50250.81352179.19243430.752277.972265.335139.721354.362202.52875.9173493.32367.598384.202266.405430.459325.303552.577753170.8075Avg353.1356666667212.288833333370.4234166667Avg439.5296666667340.805666666749.362Avg168.6733333333St dev25.745914162920.97684922925.7689640878St dev9.846006364718.04313930794.1370957733St dev11.732641326/8/096/9/0912LCC1393.825340.888292.529230.906367.3565261.717552.8195ASC1545.596288.122374.277170.26416.859272.268572.29525ASC1132.29572414.095279.052263.064139.248346.5735201.15672.708752574.779334.349443.083183.956454.564313.519570.522252132.4883420.57297.922296.446195.084359.246245.76556.74053617.565359.521496.056207.045488.543351.550568.496253134.624Avg357.7253333333236.212833333360.75625Avg453.322312.446166666770.4379166667Avg133.1359St dev10.474616584131.390392424810.5351911439St dev35.858135576239.65189673061.9009035571St dev1.29231421496/8/096/9/0913LCC1430.421321.977277.891192.486376.199235.188570.50525ASC1563.146246.21451.712131.963404.678291.837556.42025ASC189.8322420.889340.05238.105180.581380.4695209.34385.563252474.779283.319363.582162.308379.049262.94558.0522141.31593377.119342.768246.163189.618359.9435217.890571.02653507.416287.611396.553166.485397.5135281.51957.99725374.6608Avg372.204220.807333333375.6983333333Avg393.7468333333278.767166666757.4898333333Avg101.9362333333St dev10.83047495513.16732338348.54724289St dev13.223170708414.64150194080.9266907633St dev34.93722853126/10/096/11/0911LCC1432.839281.685277.259143.512357.262210.385573.43825ASC1465.66364.664368.809255.295415.162312.05251.555ASC1137.13482402.555349.089248.815208.701375.822228.75873.5322448.572376.183344.963245.474412.3775295.218558.57952137.47533376.192330.203220.878166.875353.1975193.876579.66053501.376393.654384.246252.222447.515318.23464.64053135.9719Avg362.0938333333211.006666666775.5435833333Avg425.0181666667308.501558.2583333333Avg136.8606666667St dev12.061383008717.44904428853.5656625465St dev19.532511169411.91145867436.5486592966St dev0.7882986136/10/096/11/0912LCC1408.552375.011296.204242.256391.7815269.2361.27575ASC1497.666387.338412.141275.117442.502343.62949.4365ASC1154.83412409.725384.009246.618240.05396.867243.33476.76652538.542286.075412.988189.503412.3085301.245555.53152146.50133429.369333.453281.258200.883381.411241.070570.170253460.995373.878358.684262.348417.4365310.51653.460253138.4295Avg390.0198333333251.211569.4041666667Avg424.0823333333318.463552.8094166667Avg146.5883St dev7.877155964115.64546626827.7737376239St dev16.156645260822.28143476643.0991844525St dev8.20264603896/10/096/11/0913LCC1482.863313.044339.025162.508397.9535250.766573.5935ASC1515.701350.774402.942230.907433.2375316.924558.1565ACS1147.33912426.732332.623299.75223.971379.6775261.860558.90852588.447324.828428.488193.88456.6375311.18472.726752137.39743420.362316.748281.793170.608368.555226.200571.177253496.224374.274346.573259.741435.249303.15766.0463109.7439Avg382.062246.275833333367.8930833333Avg445.94325307.170569.386375Avg131.4934666667St dev14.843595613918.24920451237.8741106971St dev12.96838504796.91532266667.2934767187St 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dev10.05486041396/4/097/2/09283LCC1476.938261.929367.568170.918369.4335269.24350.09525ASC1611.443321.676526.296228.597466.5595377.446544.5565ACS1129.73592368.068343.583283.392252.134355.8255267.76344.031252604.591346.893489.176246.311475.742367.743553.999252127.06573443.473222.554354.212140.443333.0135247.327542.8433584.003334.557478.263241.599459.28359.93149.67453123.1095Avg352.7575261.444545.6565Avg467.1938333333368.373666666749.4100833333Avg126.6370333333St dev18.402814132612.24805563143.88971216St dev8.24931179458.77473746524.7269249011St dev3.33393319876/5/097/6/0928 (31)1LCC1393.076322.741322.553243.747357.9085283.1537.37925ASC1577.899361.192475.67273.505469.5455374.587547.4792426.733297.918346.143228.993362.3255287.56837.378752583.568370.89487.234277.726477.229382.4847.3745ASC192.66023396.641298.339321.828223.755347.49272.791537.349253570.649352.65496.268267.031461.6495381.649540283.2289Avg355.908281.169833333337.3690833333Avg469.4746666667379.572333333344.9511666667390.4746St dev7.61738244087.58465774330.0171779898St dev7.78999153294.33691769394.2881544496Avg88.78796/5/097/6/0928 (31)2LCC1356.5272.656268.206188.095314.578228.150543.21375ASC1582.125295.499495.492218.97438.812357.23140.7905St dev4.93670665422342.685204.366255.799120.441273.5255188.1242.702752596.797311.574492.018220.291454.1855356.154549.0155ASC1105.3983374.431292.308280.605206.941333.3695243.77344.798253577.122260.323496.161186.921418.7225341.54138.59075296.9246Avg307.1576666667220.014543.5715833333Avg437.24351.642166666742.7989166667398.2218St dev30.604282283428.70470299881.0926177663St dev17.78368578928.76441036715.4949209522Avg100.18146666673LCC1402.04287.068342.986212.926344.554277.95633.299ASC1628.981298.712547.95190.473463.8465369.211547.3175St dev4.56397271836/5/097/6/0928 (31)2351.414310.641279.099234.097331.0275256.59837.214752599.113345.982496.916256.323472.5475376.619547.964ACS1129.7993374.116302.022285.896218.426338.069252.16142.9543629.931294.991538.239199.758462.461368.998546.73125289.5144Avg337.8835262.238333333337.8225833333Avg466.285371.609833333347.3375833333394.787St dev6.765157666313.79150196074.8561149359St dev5.46754810224.3398055640.6166203417Avg104.7001333333St dev21.89554540661LCC1ASC12233AvgAvgSt devSt dev2LCC1ASC12233AvgAvgSt devSt dev3LCC1ASC12233AvgAvgSt devSt dev1LCC1ASC12233AvgAvgSt devSt dev2LCC1ASC12233AvgAvgSt devSt dev3LCC1ASC12233AvgAvgSt devSt dev

Vessel StorageLCC = z5p0ASC = 2p5Compliancez5p0 = 856 pixels/mmz2p5 = 438 pixels/mmSacrifice DateTest DateTime (days)Mouse #VesselRingOuterInnerODIDThicknessVesselRingOuterInnerODIDThicknessVesselOAMajorMinorMajorMinorMajorMinorMajorMinor6/8/096/9/0911LCC1458.8551401869304.6927570093279.8843457944182.6647196262381.7739485981231.274532710375.2497079439ASC11237.4155251142817.38356164381080.7899543379565.83789954341027.399543379823.3139269406102.0428082192ASC1156.02012518.4147196262365.3387850467357.9626168224194.2978971963441.8767523364276.130257009382.873247663621224.6415525114775.94748858451009.4360730594527.1027397261000.294520548768.2694063927116.01255707762179.19243503.214953271324.7336448598309.9707943925163.2254672897413.9742990654236.598130841188.688084112131126.301369863839.2648401826877.1735159817608.2305936073982.7831050228742.7020547945120.04052511423170.8075Avg412.5416666667248.000973520282.2703465732Avg1003.4923896499778.095129376112.698630137Avg168.6733333333St dev30.077002526724.50566498736.7394440278St dev22.47946658641.19438198149.44542414St dev11.732641326/8/096/9/0912LCC1460.0759345794398.2336448598341.7394859813269.75429.1547897196305.744742990761.7050233645ASC11245.6529680365657.8127853881854.5136986301388.7214611872951.7328767123621.6175799087165.0576484018ASC1132.29572483.7558411215325.9953271028307.3177570093162.6728971963404.8755841122234.995327102884.940128504721312.2808219178763.35388127851011.605022831419.99086757991037.8173515982715.7979452055161.00970319632132.4883491.3200934579348.0397196262346.3154205607227.9018691589419.6799065421287.108644859866.285630841131409.9657534247820.82420091321132.5479452055472.70547945211115.394977169802.6267123288156.38413242013134.624Avg417.9034267913275.949571651170.9769275701Avg1034.9817351598713.347412481160.8171613394Avg133.1359St dev12.236701616936.671019187912.3074662895St dev81.867889443390.52944459044.3399624591St dev1.29231421496/8/096/9/0913LCC1502.828271028376.1413551402324.6390186916224.8668224299439.4848130841274.752920560782.3659462617ASC11285.7214611872562.12328767121031.3059360731301.2853881279923.9223744292666.2956621005128.8133561644ASC189.8322491.6927570093397.2546728972278.160046729210.9591121495444.4737149533244.559579439399.95706775721083.9703196347646.8470319635830.095890411370.5662100457865.4086757991600.3310502283132.53881278542141.31593440.5595794393400.4299065421287.5735981308221.5163551402420.4947429907254.544976635582.974883177631158.4840182648656.6461187215905.3721461187380.102739726907.5650684932642.7374429224132.4138127854374.6608Avg434.8177570093257.952492211888.4326323988Avg898.9653729072636.454718417131.2553272451Avg101.9362333333asc seems a little smaller than restSt dev12.652424012815.38238713029.9850968341St dev30.189887462133.42808662292.1157323364St dev34.93722853126/9 avg421.7542834891260.634345794480.55996884746/10/096/11/0911LCC1505.6530373832329.0712616822323.9007009346167.6542056075417.3621495327245.77745327185.7923481308ASC11063.1506849315832.5662100457842.0296803653582.8652968037947.8584474886712.4474885845117.7054794521ASC1137.13486/9 stdev11.626601963614.1659905538.85265224332470.2745327103407.8142523364290.671728972243.8095794393439.0443925234267.240654205685.901869158921024.1369863014858.8652968037787.5867579909560.4429223744941.5011415525674.0148401826133.74315068492137.47533439.476635514385.7511682243258.035046729194.9474299065412.6139018692226.491238317893.061331775731144.6940639269898.7534246575877.2739726027575.84931506851021.7237442922726.5616438356147.58105022833135.9719Avg423.0068146417246.503115264888.2518496885Avg970.3611111111704.3413242009133.0098934551Avg136.8606666667St dev14.090400711120.38439753334.1654936291St dev44.594774359427.195111128614.9512769329St dev0.7882986136/10/096/11/0912LCC1477.2803738318438.0969626168346.0327102804283.0093457944457.6886682243314.521028037471.5838200935ASC11136.2237442922884.3333333333940.9611872146628.12100456621010.2785388128784.5410958904112.8687214612ASC1154.83412478.6507009346448.6086448598288.1051401869280.4322429907463.6296728972284.268691588889.680490654221229.5479452055653.1392694064942.894977169432.6552511416941.3436073059687.7751141553126.78424657532146.50133501.5992990654389.5478971963328.5724299065234.6764018692445.5735981308281.624415887881.974591121531052.5853.602739726818.9132420091598.9680365297953.051369863708.9406392694122.05536529683138.4295Avg455.6306464174293.471378504781.0796339564Avg968.2245053272727.0856164384120.5694444444Avg146.5883St dev9.202285004818.27741386479.0814691868St dev36.88731794750.87085563117.0757635903St dev8.20264603896/10/096/11/0913LCC1564.0922897196365.7056074766396.0572429907189.8457943925464.8989485981292.951518691685.9737149533ASC11177.399543379800.8538812785919.9589041096527.1849315068989.1267123288723.5719178082132.7773972603ASC1147.33912498.5186915888388.578271028350.1752336449261.648364486443.5484813084305.911799065468.818341121521343.4863013699741.6164383562978.2831050228442.64840182651042.551369863710.4657534247166.04280821922137.39743491.0771028037370.0327102804329.1974299065199.308411215430.5549065421264.252920560783.150992990731132.9315068493854.5068493151791.2625570776593.0159817352993.7191780822692.1392694064150.78995433793109.7439Avg446.3341121495287.705412772679.3143496885Avg1008.4657534247708.7256468798149.8700532725Avg131.4934666667St dev17.340649081721.31916414999.1987274499St dev29.608185040815.788407914616.6517733303St dev19.48055664926/11 avg441.6571910696275.893302180782.8819444444ONE DAY AVERAGESAvg431.7057372793268.263823987581.7209566459980.74847793711.3416412988134.7034183156136.44798333336/11 stdev16.807254178625.61540367474.7334943629ONE DAY ST DEVSt dev21.536929227127.61149887879.674066566458.526136662859.551678947419.033882500725.11011768786/9/096/12/0931LCC1447.125435.0689252336294.7488317757279.9707943925441.0969626168287.359813084176.8685747664ASC11272.0570776256762.82648401831010.6575342466514.18493150681017.4417808219762.4212328767127.5102739726ASC1135.46512498.6191588785424.6764018692324.3072429907256.6764018692461.6477803738290.491822429985.57797897221438.7716894977646.34474885841196.3082191781351.55022831051042.5582191781773.9292237443134.31449771692161.26983486.8119158878379.8644859813330.8773364486206.1004672897433.3382009346268.488901869282.424649532731194.7853881278847.1141552511906.6506849315550.55022831051020.9497716895728.600456621146.17465753423141.325Avg445.3609813084282.113512461181.6237344237Avg1031.7539954338751.2648401826140.2445776256Avg146.0199666667St dev14.628549605411.9027257794.4095951246St dev15.279479750132.05227861578.3863994328St dev13.52784792656/9/096/12/0932LCC1482.9018691589432.2453271028301.6331775701248.1413551402457.5735981308274.887266355191.3431658879ASC11314.7305936073885.26484018261070.4885844749530.30821917811099.997716895800.3984018265149.7996575342ASC1161.76822489.1261682243428.6378504673322.2792056075289.1109813084458.8820093458305.695093457976.593457943921410.6301369863724.75799086761153.8356164384469.54109589041067.6940639269811.6883561644128.00285388132144.62333467.9170560748371.6144859813326.1238317757221.7862149533419.765771028273.955023364572.905373831831246.1141552511887.1666666667976.703196347624.10730593611066.6404109589800.4052511416133.11757990873143.8441Avg445.4071261682284.845794392580.2806658879Avg1078.1107305936804.1640030441136.9733637747Avg150.0785333333St dev22.215699517418.06203817099.7562631572St dev18.96200604276.516281849111.3984851751St dev10.13104230786/9/096/12/0933LCC1484.2137850467391.5128504673335.8691588785256.1962616822437.863317757296.032710280470.9153037383ASC11358.4223744292690.52054794521077.794520548438.33105022831024.4714611872758.0627853881133.2043378995ASC1122.11382539.9976635514353.2172897196403.9672897196213.5934579439446.6074766355308.780373831868.913551401921261.1940639269910.5547945205996.7602739726610.84931506851085.8744292237803.8047945205141.03481735162116.96543496.4158878505394.5432242991330.5362149533252.5817757009445.4795560748291.558995327176.960280373831343.9200913242718.23059360731086.4794520548447.05707762561031.0753424658766.7682648402132.15353881283128.9432Avg443.3167834891298.790693146472.2630451713Avg1047.1404109589776.2119482496135.4642313546Avg122.6741333333St dev4.75639228478.93581677954.1892442057St dev33.706764012424.28930252444.8527946528St dev6.00852754796/12 avg444.6949636552288.583333333378.0558151616/22/096/25/0931 (4)LCC1470.3925233645279.9275700935313.2126168224144.4427570093375.160046729228.827686915973.1661799065ASC11118.00456621995.6301369863880.99543379777.07077625571056.8173515982829.0331050228113.8921232877ASC1143.44736/12 stdev1.19376202188.94477427915.06143224662464.5257009346320.660046729333.1787383178175.9871495327392.5928738318254.582943925269.004964953321116.7945205481027.897260274861.3378995434756.27397260271072.345890411808.8059360731131.7699771692114.95293510.3446261682281.5140186916351.3563084112139.8107476636395.9293224299245.583528037475.172897196331163.002283105948.0068493151850.1461187215653.81278538811055.50456621751.9794520548151.76255707763128.924Avg387.8940809969242.998052959572.4480140187Avg1061.5559360731796.6061643836132.4748858447Avg129.1080666667St dev11.153461071113.07083880013.146056058St dev9.367400243939.949245060318.9450550551St dev14.24809174046/22/096/25/0932 (5)LCC1512.6004672897315.1425233645363.2172897196151.5689252336413.8714953271257.393107476678.2391939252ASC11247.7374429224842.0936073059987.8584474886503.73287671231044.9155251142745.7956621005149.5599315068ASC1158.15442452.453271028419.4567757009295.2815420561243.9450934579435.9550233645269.61331775783.170852803721190.0639269406969.5091324201838.5296803653705.34018264841079.7865296804771.9349315068153.92579908682111.01383487.8563084112338.4392523364325.8563084112218.4007009346413.1477803738272.128504672970.509637850531340.0342465753733.1164383562992.0753424658425.46803652971036.5753424658708.7716894977163.901826484392.9457Avg420.9914330218266.378309968877.3065615265Avg1053.7591324201742.1674277017155.7958523592Avg120.7046333333St dev12.96390056247.88238156756.3819231754St dev22.922886331431.73754635947.3515516944St dev33.66716244276/22/096/25/0933 (6)LCC1521.203271028367.601635514353.9497663551215.6320093458444.402453271284.790887850579.8057827103ASC11147.0684931507878.5936073059892.6255707763648.84703196351012.8310502283770.7363013699121.0473744292ASC1160.68252456.5841121495398.5654205607340.796728972259.3247663551427.5747663551300.060747663663.757009345821205.8744292237969.4931506849976.9817351598732.43835616441087.6837899543854.7100456621116.48687214612139.10433527.296728972375.5887850467355.3142523364204.2651869159451.4427570093279.789719626285.826518691631323.9497716895879.0958904111039.3630136986588.46803652971101.5228310502813.9155251142143.803652968391.8004Avg441.1399922118288.213785046776.4631035826Avg1067.345890411813.1206240487127.1126331811Avg130.5290666667St dev12.263889415210.560104797611.4081522827St dev47.71562233441.992515206814.633596667St dev35.232611245THREE DAY AVERAGES430.6850661994277.223357995876.73085410181055.8158929477781.2089675292137.3034627093133.1857333333THREE DAY ST DEV24.523827021221.22059829367.077922823828.556132538736.915152020713.63943026421.7191364246/11/096/25/09141LCC1570.6857476636292.476635514419.3551401869180.9976635514431.5811915888300.176401869265.7023948598ASC11446.0410958904799.14383561641096.0502283105491.34703196351122.5924657534793.698630137164.4469178082ASC1123.40682537.7313084112339.1857476636370.5327102804167.953271028438.4585280374269.242990654284.607768691621386.3561643836801.68493150681086.502283105564.73972602741094.0205479452825.6210045662134.19977168952114.45353520.5771028037394.5934579439346.0817757009241.8177570093457.5852803738293.949766355181.817757009331339.6073059361871.69178082191009.098173516554.34931506851105.649543379781.7237442922161.96289954343136.8768Avg0000442.5416666667287.789719626277.3759735202Avg00001107.4208523592800.3477929985153.5365296804Avg124.9123666667St dev000013.474315351216.360886715810.2054088773St dev000014.368081759122.691427675616.7921185049St dev11.28721152296/11/096/25/09142LCC1480.6787383178362.1028037383329.9042056075206.566588785421.390771028268.235397196376.5776869159ASC11358.9315068493926.3630136986932.4931506849556.91552511421142.647260274744.7043378995198.9714611872ASC1112.34742518.4964953271328.0712616822353.148364486191.7745327103423.2838785047272.461448598175.411214953321311.8538812785876.399543379930.0410958904616.56392694061094.1267123288773.3025114155160.41210045662102.12543507.875349.5689252336338.5046728972200.7698598131428.7219626168269.637266355179.542348130831357.5593607306769.47488584471090.0707762557475.87899543381063.5171232877782.9748858447140.27111872153124.5973Avg0000424.4655373832270.111370716577.1770833333Avg00001100.0970319635766.9939117199166.5515601218Avg113.0233666667St dev00003.80576284162.15254705452.1297939763St dev000039.901480953419.899938004829.8278774829St dev11.25118974176/11/096/25/09143LCC1433.7675233645410.8072429907305.4988317757286.4719626168422.2873831776295.985397196363.1509929907ASC11135.5867579909995.2579908676859.3926940639658.52283105021065.4223744292758.9577625571153.2323059361ASC1119.05972505.9357476636421.7745327103349.2464953271262.6880841122463.8551401869305.967289719678.943925233621426.2808219178679.72831050231094.2305936073362.55936073061053.00456621728.394977169162.30479452052112.34333490.4953271028373.3668224299342.6144859813223.1156542056431.9310747664282.865070093574.533002336431359.8652968036726.01598173521076.4132420091406.87442922371042.9406392694741.6438356164150.64840182653128.3485Avg439.3578660436294.939252336472.2093068536Avg1053.7891933029742.9988584475155.3951674277Avg119.9171666667St dev21.756321545811.58658501098.1488556087St dev11.261386846415.32638339026.1217930407St dev8.03697975446/25 avg426.065096054275.071748442475.49667380586/12/096/26/09141LCC1432.4742990654322.410046729301.9497663551204.6051401869377.4421728972253.27745327162.0823598131ASC11182.016563147709.8322981366943.2215320911491.1138716356945.9244306418717.1677018634114.3783643892ASC1122.12756/25 st dev20.788240148319.27734831212.47654322182466.0035046729266.7721962617340.0957943925139.5093457944366.3878504673239.802570093563.292640186921191.7908902692742.78674948241012.8053830228505.734989648967.2888198758759.2701863354104.00931677022149.68013442.1343457944304.1775700935287.1728971963177.7511682243373.1559579439232.462032710370.346962616831235.7432712215658.5403726708988.4140786749397.2795031056947.1418219462692.8467908903127.1475155283140.6603Avg372.3286604361241.847352024965.2406542056Avg953.4516908213723.0948930297115.1783988958Avg137.4893St dev5.573403535610.55728578474.4634049602St dev11.998754758333.606034606311.5898275159St dev14.04734396396/12/096/26/09142LCC1433.1962616822403.2815420561304.714953271281.4544392523418.2389018692293.084696261762.5771028037ASC11353.7805383023544.08902691511073.4699792961312.9751552795948.9347826087693.2225672878127.8561076605ASC1154.20622480.0829439252411.3072429907334.2581775701263.7102803738445.6950934579298.98422897273.35543224321321.9109730849579.42650103521116.3913043478345.2587991718950.66873706730.8250517598109.92184265012142.06183564.0560747664318.8574766355400.7628504673165.023364486441.4567757009282.893107476679.281834112131131.0724637681869.4182194617909.2836438923639.22567287781000.2453416149774.2546583851112.99534161493153.7358Avg435.1302570093291.654010903471.738123053Avg966.6162870945732.7674258109116.9244306418Avg150.0012666667St dev14.78104337348.1404049778.4689892422St dev29.136517129940.55095016919.5910255344St dev6.87980139646/12/096/26/09143LCC1439.9964953271349.7289719626316.7593457944238.9964953271394.8627336449277.877920560758.4924065421ASC11171.6438923395796.3830227743953.6666666667562.0434782609984.0134575569757.8550724638113.0791925466ASC1106.86172440.1682242991335.7079439252323.5852803738208.9579439252387.9380841122266.271612149560.833235981321241.1904761905587.77846790891046.0310559006375.4492753623914.4844720497710.7401656315101.8721532091297.6763415.5537383178372.2231308411293.4778037383254.7990654206393.8884345794274.138434579459.87531227.9958592132598.66459627331036.5134575569399.6832298137913.3302277433718.098343685397.6159420293147.857Avg392.2297507788272.762655763259.7335475078Avg937.27605245728.8978605935104.1890959282Avg117.4649St dev3.74848192615.92420241441.1768080649St dev40.479894356125.34611973347.9877529265St dev26.71804779416/26 avg399.8962227414268.754672897265.5707749221Fourteen Day Averages417.675623053276.517393561870.57911474561019.7751846652749.1834571135.2958637826127.134727777832.095034309125.14406017636.0090925497Fourteen Day St Dev28.998055359920.431870212318.219409726775.567314324536.078771038527.937920785217.97626855286/15/096/29/09141LCC1529.5128504673290.5198598131443.3609813084197.1553738318410.0163551402320.258177570144.879088785ASC11391.3150684932873.93378995431150.1757990868633.88356164381132.6244292237892.0296803653120.2973744292ASC1128.74242495.7593457944383.4112149533382.2476635514261.2476635514439.5852803738321.747663551458.918808411221482.4885844749635.69178082191242.5684931507375.11415525111059.0901826484808.8413242009125.12442922372155.2293418.9299065421400.7172897196312.546728972262.3200934579409.8235981308287.43341121561.195093457931418.9680365297706.54794520551202.4680365297480.35388127851062.7579908676841.4109589041110.67351598173126.1078Avg419.808411215309.813084112254.9976635514Avg1084.8242009132847.4273211568118.6984398782Avg136.6930666667St dev17.127542267119.39566862378.8365454155St dev41.436814237941.91924511967.3569468637St dev16.10654828616/15/096/29/09142LCC1537.0338785047284.8504672897363.5630841122143.9252336449410.9421728972253.744158878578.5990070093ASC11447.6940639269702.05479452051211.3196347032490.14840182651074.8744292237850.7340182648112.0702054795ASC1135.93242514.796728972267.9299065421371.5151869159113.1273364486391.363317757242.321261682274.521028037421495.8219178082589.11187214611279.7237442922320.24657534251042.4668949772799.9851598174121.24086757992103.89743454.3820093458360.9205607477286.5128504673201.964953271407.6512850467244.238901869281.706191588831315.2876712329895.64155251141108.0342465753616.79452054791105.4646118722862.4143835616121.52511415533121.1434Avg403.3189252336246.768107476678.2754088785Avg1074.2686453577837.7111872146118.2787290715Avg120.3244St dev10.48379217236.11705042023.6034956123St dev31.503227042133.18957051175.3786171944St dev16.03319609446/15/096/29/09143LCC1461.7873831776328.9065420561335.6413551402211.7546728972395.3469626168273.698014018760.8244742991ASC11389.6506849315593.97031963471180.0890410959343.50456621991.8105022831761.796803653115.0068493151ASC1120.63062515.9404205607362.9182242991391.933411215241.703271028439.4293224299316.818341121561.305490654221217.4543378995783.06849315071024.1278538813550.93835616441000.2614155251787.5331050228106.36415525112138.21713520.2651869159306.5689252336391.7546728972199.9906542056413.4170560748295.872663551458.772196261731173.7716894977832.44748858451002.7853881278640.11872146121003.1095890411821.452054794590.82876712333119.9152Avg416.0644470405295.463006230560.300720405Avg998.3938356164790.2606544901104.0665905632Avg126.2543St dev22.160102004921.56308226351.3454121027St dev5.876498228329.921010874712.251694464St dev10.36626196716/29 avg413.0639278297284.014732606464.52459761166/16/096/30/09141LCC1448.9474299065406.0887850467326.6705607477292.8154205607427.5181074766309.742990654258.8875584112ASC11545.2694063927679.22374429221292.6621004566411.69406392691112.2465753425852.1780821918130.0342465753ASC1141.93916/29 st dev8.644542997333.044886086512.20017257552447.7978971963368.2803738318331.5035046729251.9859813084408.039135514291.744742990758.147196261721377.7146118722789.67808219181120.9680365297532.3013698631083.696347032826.6347031963128.53082191782145.62273522.8177570093349.8855140187378.1950934579229.5436.351635514303.84754672966.252044392531424.894977169731.94748858451192.6735159817467.24429223741078.4212328767829.9589041096124.23116438363140.8742Avg423.9696261682301.778426791361.0955996885Avg1091.454718417836.2572298326127.5987442922Avg142.812St dev14.48596575179.17579275744.4809290909St dev18.198425567713.88768277333.0117299441St dev2.49169196936/16/096/30/09142LCC1471.7464953271402.714953271345.9672897196238.0408878505437.2307242991292.00408878572.613317757ASC11253.6369863014881.51019.6917808219659.22602739731067.5684931507839.4589041096114.0547945205ASC1141.87082490.8668224299411.8714953271343.7184579439256.7862149533451.3691588785300.252336448675.55841121521368.7694063927840.84931506851151.8333333333616.26712328771104.8093607306884.0502283105110.379566212145.03353454.6460280374325.3656542056323.5619158878215.3364485981390.0058411215269.44918224360.278329439331356.2922374429702.07762557081167.7077625571475.43150684931029.1849315068821.5696347032103.80764840183143.0488Avg426.2019080997287.235202492269.4833528037Avg1067.1875951294848.3595890411109.4140030441Avg143.3177St dev32.13394282715.94569799698.1066475947St dev37.81365343832.17720914825.191361581St dev1.59840490186/16/096/30/09143LCC1515.5432242991264.3060747664393.9871495327132.7897196262389.9246495327263.388434579463.2681074766ASC11259.5776255708796.95205479451057.8515981735584.68264840181028.2648401826821.2671232877103.4988584475ASC1154.3732484.1471962617355.6214953271342.6740654206226.9871495327419.8843457944284.830607476667.526869158921244.50456621823.06164383561050.3493150685593.0981735161033.7831050228821.7237442922106.02968036532100.51183518.5070093458307.0257009346396.3317757009185.0852803738412.7663551402290.708528037461.028913551431199.5639269406836.5913242009959.497716895604.94063926941018.0776255708782.2191780822117.92922374433171.8155Avg407.5251168224279.642523364563.941296729Avg1026.7085235921808.403348554109.152587519Avg142.2334333333St dev15.6524370114.37998745493.3008702786St dev7.96756626622.67730612667.7054054058St dev37.1696276221Fourteen Day (Frozen) Averages416.1480724299286.783391744564.68234034271057.1395865043828.0698883815114.5348490614135.2724833333Fourteen Day (Frozen) St Dev18.79821845924.610567351617.232767438741.503653274933.677639295510.167669742217.91979386216/23/096/30/0971 (4)LCC1580.4485981308330.2009345794412.4871495327194.6565420561455.3247663551303.571845794475.8764602804ASC11259.1757990868933.21461187211023.0410958904691.5981735161096.1952054794857.3196347032119.4377853881ASC1142.68082550.0011682243303.898364486382.3808411215124.4637850467426.9497663551253.422313084186.763726635521334.0342465753752.29223744291157.2808219178555.97260273971043.1632420091856.626712328893.26826484022161.73453536.0490654206394.3948598131363.7091121495216.0420560748465.2219626168289.875584112287.673189252331335.404109589790.25570776261076.4132420091560.69178082191062.8299086758818.5525114155122.13869863013145.1476Avg449.1654984424282.289914330283.4377920561Avg1067.3961187215844.1662861492111.6149162861Avg149.8543lcc thick may be higher hereSt dev19.865615711325.92104738046.564075276St dev26.809233353722.18488511215.9459539553St dev10.36222174976/23/096/30/0972 (5)LCC1533.2768691589315.2278037383414.578271028191.2943925234424.2523364486302.936331775760.6580023364ASC11296.5662100457648.24885844751097.7853881278442.1073059361972.4075342466769.946347032101.2305936073ASC1149.44092494.1775700935281.6273364486374.078271028167.0163551402387.902453271270.547313084158.677570093521279.1301369863849.27397260271107.2831050228598.23059360731064.2020547945852.7568493151105.72260273972169.73500.7359813084387.398364486362.6810747664258.6355140187444.0671728972310.658294392566.704439252331179.9863013699938.5799086758960.5114155251719.71461187211059.2831050228840.1130136986109.58504566213142.0052Avg418.7406542056294.713979750862.0133372274Avg1031.9642313546820.9387366819105.5127473364Avg153.7153666667St dev28.485134957221.28210539394.1815495481St dev51.63621930944.61092351024.1811776752St dev14.33365918826/23/096/30/0973 (6)LCC1512.828271028353.1892523364363.6764018692207.0362149533433.0087616822285.356308411273.8262266355ASC11402.7305936073609.46803652971171.5407.50684931511006.0993150685789.5034246575108.2979452055ASC1177.5862459.2838785047368.2067757009315.0911214953245.2523364486413.7453271028280.17172897266.786799065421217.2785388128867.5593607306998.2648401826663.65525114161042.4189497717830.9600456621105.72945205482146.82863446.0093457944288.0514018692307.2838785047174.3563084112367.0303738318240.820093457963.105140186931246.203196347748.52511415531065.5433789954528.801369863997.3641552511797.1723744292100.0958904113162.1055Avg404.5948208723268.782710280467.906055296Avg1015.2941400304805.8786149163104.7077625571Avg162.1733666667St dev33.927654487824.3546899115.4474741433St dev23.893351206622.05701303084.1953918512St dev15.37881231126/30 avg421.6996041018285.740459501667.97957230017day 6/30 avg424.1669911734281.928868120571.11906152656/24/097/1/0971LCC1463.5735981308321.5175233645339.5226.8679906542392.5455607477283.183995327154.6807827103ASC11434.2739726027783.42009132421149.9520547945523.64611872151108.8470319635836.799086758136.0239726027ASC1132.05736/30 stdev16.012771008511.63297952228.252466637622.775429182112.969404375711.06771760372609.6051401869246.1226635514454.023364486125.5560747664427.8639018692289.789719626269.037091121521340.2671232877991.97716894981093.5502283105736.06392694061166.1221461187914.8070776256125.65753424662129.49053542.1063084112254.8528037383392.3656542056154.7418224299398.4795560748273.553738317862.462908878531533.2168949772769.01598173521239.7739726027529.66894977171151.1164383562884.7214611872133.19748858453103.29Avg406.2963395639282.17581775762.0602609034Avg1142.0285388128878.7758751903131.6263318113Avg121.6126St dev18.9122416178.16480794457.1866189438St dev29.69936218139.34239639925.3588395435St dev15.91965353366/24/097/1/0972LCC1520.9088785047335.7955607477424.5257009346245.5887850467428.3522196262335.057242990746.6474883178ASC11223.44748858451170.8584474886986.7534246575874.91780821921197.1529680365930.8356164384133.1586757991ASC1133.36152517.7815420561341.6425233645394.9813084112197.9918224299429.7120327103296.486565420666.612733644921312.7579908676815.74429223741097.5639269406579.18949771691064.2511415525838.3767123288112.93721461192149.7943500.566588785371.5502336449403.6343457944261.2067757009436.058411215332.420560747751.818925233631313.1849315068887.13013698631092.6392694064702.71004566211100.1575342466897.6746575342101.24143835623143.426Avg431.3742211838321.321456386355.0263823988Avg1120.5205479452888.9623287671115.779109589Avg142.1938333333St dev4.113210436121.548013371810.3618816507St dev68.751095379446.84112233616.1472841925St dev8.28525437656/24/097/1/0973LCC1447.9521028037411.3317757009340.5549065421294.9801401869429.6419392523317.767523364555.9372079439ASC11337.803652968854.01826484021119.2100456621607.28538812791095.9109589041863.247716895116.3316210046ASC1135.21462491.726635514384.2418224299364.785046729262.1869158878437.984228972313.485981308462.249123831821245.2442922374936.5616438356998.8150684932722.06164383561090.9029680365860.4383561644115.23230593612168.0263489.4182242991357.1635514019361.0420560748254.5490654206423.2908878505307.795560747757.747663551431460.698630137706.82648401831218.1301369863447.03424657531083.7625570776832.5821917808125.59018264843129.9412Avg0000430.3056853583313.016355140258.644665109Avg1090.1921613394852.0894216134119.051369863Avg144.3939333333St dev7.36912393025.00254147023.2501583638St dev6.105313370716.95205411555.6893916974St dev20.63511856267/1 avg422.658748702305.504543094558.5771028037Seven Day Averages423.4128699377293.716705607564.84808216511077.8992897007848.4685438864114.7153729072145.65723333337/1 stdev14.180330278420.62560898693.5174259343Seven Day St Dev24.133332633524.983353562810.945606917857.324631073941.643646033212.657142405717.88139592086/4/097/2/0928 (1 mo)1LCC1490.2394859813342.8621495327386.0911214953242.5747663551416.550817757314.332943925251.1089369159ASC11150.6118721461909.1461187215961.3675799087708.22146118721029.8789954338834.794520547997.5422374429ASC1121.74362420395.5922897196337.2768691589305.1635514019407.7961448598321.220210280443.287967289721240.4726027397810.3972602741016.6598173516555.44292237441025.4349315068786.051369863119.6917808219296.28573452.9112149533298.8656542056337.5911214953208.4205607477375.8884345794273.005841121551.44129672931215.0365296804797.51141552511043.5433789954583.76484018261006.2739726027813.65410958996.30993150683144.5062Avg400.0784657321302.852998442448.6127336449Avg1020.5292998478811.5104.5146499239Avg120.8451666667St dev21.401618624726.07677529084.6143762649St dev12.543850772224.442868607513.1582149702St dev24.12280128646/4/097/2/0928 (1 mo)2LCC1479.0689252336372.8738317757377.5023364486273.8796728972425.9713785047325.691004672950.1401869159ASC11308.8127853881894.47031963471095.63470319