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Alzheimer’s disease and treatment
Eman youssif
Medical research institute2013
The content:*structure of the brain
*risk factors
*mechanism of Alzheimer’s disease
*symptoms
*treatment
Hearing Words Speaking Words Seeing Words Thinking
structure
Hippocampus: where short-term memories are converted to long-term memories
Continue introduction
Proteins present normally in the brain
Risk factors
1-genetic factor
2 -environmental factor
3 -age
4-life style
medication
smoking
Sleep deprivation
Depression and stress
Nutritional deficiency
Mechanism of Alzheimer’s disease
video
?Inside the Brain Unraveling the Mystery of Alzheimer's Disease [HQ]?þ.webm
Accumulation of beta amyloid
TAU protein
Change of the brain
Affected regions begin to shrink as nerve cells die .
Symptoms of Alzheimer’s disease
Stage 1 (Mild) 2 to 4 years
depression
Less energetic Getting lostRepetitive
questions and conversations
Losing things or misplacing them in
odd places
Noticeable changes in
personality or mood
Stage 2
Stage 2 (Moderate): 2 to 10 years
Forget recent events and their personal history
More disoriented and disconnected
from reality
Speech problems arise and
understanding
Reading and writing are more
difficult
Stage 3
Stage 3 (Severe) : 1 to 3 years during final stage
lose the ability to feed themselves, speak,
recognize people and control bodily
functions.
Their memory worsens and may become
almost non-existent. They will sleep often.
Stage 3 =memory loss
Treatment for stage 1Stay calm and be understanding.
Be patient and flexible. Don’t argue or try to convince.
Acknowledge requests and respond to them
Treatment for stage 1
Music therapy
In Alzheimer disruption of wavesso music can alter this disruption
So the result change the moodtreatment the first stage of Alzheimer
Treatment for stage 2Color therapy
drugs
Donepezil ,rivastigmine and galantamine
Increase communication between the nerve cells
Temporarily improve or stabilize the symptoms of Alzheimer’s disease
Finally advise to you
Advise to you
references
Books:
1-Strategies for creating better care environmentBib Alex2-the encyclopedia of ALZ.. Disease –bib Alex3-designing for Alzheimer’s disease-bib Alex
web site:http://www.alz.org/aaic/overview.asp?gclid=CLyHlciwir0CFeFZ2wodAxUASAhttp://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=147http://www.mayoclinic.org/diseases-conditions/alzheimers-disease/basics/causes/con-20023871http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-genetics-fact-sheethttp://www.nature.com/nrn/posters/ad/index.htmlhttp://www.ncbi.nlm.nih.gov/pubmed/10653281http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013812http://med.stanford.edu/news_releases/2007/july/music.htmlhttp://www.health.harvard.edu/newsweek/Preventing_memory_loss.htm
Lectures::
Neurology lec. By prof .dr .Mohamed B. Abou – Donia –December 2013Apoptosis course –medical research institute
Photo reference:
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