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Allergies in America: A Landmark Survey of Nasal Allergy Sufferers Conducted by Schulman, Ronca & Bucuvalas, Inc. February 17, 2006 Supported by:

Allergies in America: A Landmark Survey of Nasal Allergy Sufferers Conducted by Schulman, Ronca & Bucuvalas, Inc. February 17, 2006 Conducted by Schulman,

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Allergies in America: A Landmark Survey of Nasal Allergy Sufferers

Conducted bySchulman, Ronca & Bucuvalas, Inc.

February 17, 2006

Conducted bySchulman, Ronca & Bucuvalas, Inc.

February 17, 2006

Supported by:

2

QA. Including yourself, how many persons, aged 18 and older, live in this household (even if they are not there right now)? QB. Have any of these persons been diagnosed as having hay fever, rhinitis, or nasal

allergies? QC. How many persons, 18 or older, in this household have been diagnosed with hay fever, rhinitis or nasal allergies? N=61,655 adults in 31,470 households

Not diagnosed, 86%

Diagnosed, 14%

Adults Diagnosed with Nasal Allergies: Household Screening

3

QD. Has this person/have these persons had symptoms like sneezing, itching, watery eyes, nasal congestion, or other nasal allergy symptoms in the past 12 months? QE. Does this person/do any of these persons take any medication for their hay fever, rhinitis or nasal allergies? N=6,315 households with allergic

rhinitis

2%17%

76%5%

Current Nasal Allergies: Household Screening

4

10%12%

21%22%

17%15%

3%

5%

11%

22%

25%

20%

15%

1%

0%

10%

20%

30%

40%

50%

18-24 25-34 35-44 45-54 55-64 65 and older Refused

Screened Interviewed

QH. What is the age/ages of the person/persons with nasal allergies, rhinitis or hay fever? N=7,758 QD3. What is your age? N=2,500

Age of Persons with Nasal Allergies

5

Gender of Persons with Nasal Allergies

40%

60%

35%

65%

0%

20%

40%

60%

80%

100%

Male Female

Screened Interviewed

QH. What is the gender of the person/persons with nasal allergies, rhinitis or hay fever? N=4,614 QMGEN. Gender of respondent? N=2,500

6

Diagnosed with Nasal Allergies: Individual Screening

10%90%

QS1A. Has a doctor ever diagnosed you as having hay fever, rhinitis, or nasal allergies? Base: Persons identified as having been diagnosed and symptomatic or being treated for nasal allergies in household screen N=3,257

7

Current Nasal Allergies: Individual Screening

1%

32%

64%2%

QS1b. Do you still suffer from hay fever or nasal allergies? S1c. When was the most recent time that you experienced hay fever or symptoms of nasal allergies for a month or longer? QS2. In the past 12 months, have you taken a prescription medication to treat your nasal allergies? N=2,933 persons diagnosed

8

General Health Status

Poor/Very Poor4%

Fair12%

Good32%

Excellent19%

Very good33%

Q1. In general, would you say your health is excellent, very good, good, only fair, poor or very poor? Unweighted N=2,500

9

Asthma and Allergies

Never68%

Past 12 months20%

Not past 12 months12%

Q3c. Have you ever been diagnosed with asthma? Q3d. Have you had asthma in the past 12 months? Unweighted N=2,500

10

When Diagnosed With Nasal Allergies

7%

15%

18%

21%

14%

9%

5% 4%

7%

0%

5%

10%

15%

20%

25%

Under 6 6-11 12-17 18-29 30-39 40-49 50-59 60 andolder

Not sure

Q4. At what age were you first diagnosed with nasal allergies, rhinitis or hay fever? Unweighted N=2,500

11

Who Diagnosed Nasal Allergies

27%

20%

19%

12%

5%

4%

1%

1%

3%

8%

0% 10% 20% 30% 40% 50%

General Practice

Family Practice

Allergist

ENT

Pediatrician

Internal Medicine

Pulmonologist

Specialty Unknown

Other

Not sure

Q5. What was the medical specialty of the doctor who diagnosed you with nasal allergies? Unweighted N=2,500

12

Skin and Blood Tests for Allergies

Blood test only 8%

Not sure2%

Neither42%

Skin test only33%

Both15%

Q6a. Were you given a skin test to see what you were allergic to? Q6b. Were you given a blood test to see what you were allergic to? Unweighted N=2,500

13

Seasonal or Persistent Allergies

Not sure1%

Seasonal43%

Throughout the year56%

Q12. Would you describe your nasal allergies as seasonal or do they occur throughout the year? Unweighted N=2,500

14

Allergy Symptoms Worse During a Particular Season or Time of Year

71%

79%

66%

0%

20%

40%

60%

80%

100%

All Seasonal Persistent

Q12. Would you describe your nasal allergies as seasonal or do they occur throughout the year? Q13a. In the past 12 months, have your nasal allergy symptoms been more frequent or worse during a particular

season or time of year? Unweighted N=2,500

15

Season Allergies Are the Worse

56%

21%

45%

23%

0%

20%

40%

60%

80%

100%

Spring Summer Fall Winter

Q13b. During what times of the year are your nasal allergies the worse? Base: Worse at certain times Unweighted N=1,778

16

Allergies Worse Outdoors or Inside

Not sure1%

Same51%

Outside39%

Inside9%

Q13c. Are your nasal allergies worse when you are outdoors or inside, or is it about the same? Unweighted N=2,500

17

Symptoms During Worst Month

29%

25%

40%

12%

23%

13%

6%

11%

28%

30%

17%

15%

20%

10%

12%

12%

6%

10%

17%

16%

0% 20% 40% 60% 80% 100%

Repeated Sneezing

Watering Eyes

Stuffed up nose

Awakened / Unable to Sleep

Itching

Headache

Ear Pain

Facial Pain

Runny Nose

Post-nasal drip

Every day

Most days

Q14. During the worst one month period in the past year, did you have (symptom) every day, most days a week, a few days a week, a few days a month, less than that, or never? Unweighted N=2,500

18

How Bothersome are Symptoms

11%

16%

28%

26%

19%

33%

20%

28%

26%

25%

18%

40%

23%

20%

38%

36%

27%

31%

30%

31%

0% 20% 40% 60% 80% 100%

Repeated Sneezing

Watering Eyes

Red, itching eyes

Stuffed up nose

Itching

Headache

Ear Pain

Facial Pain

Runny Nose

Post-nasal drip

Extremely

Moderately

Q15. When you have nasal allergy attacks, how bothersome are the following symptoms usually --- extremely bothersome, moderately bothersome, slightly bothersome, or not bothersome ? Unweighted N=2,500

19

Most Bothersome Symptom

22%

14%

14%

10%

10%

9%

7%

5%

4%

4%

0% 5% 10% 15% 20% 25%

Stuffed up nose

Headache

Post-nasal drip

Red, itching eyes

Runny Nose

Repeated Sneezing

Facial Pain

Watering Eyes

Ear Pain

Itching

Most bothersome

Q16. Which of these symptoms was the most bothersome to you? Base: Had bothersome symptoms. Unweighted N=2,362

20

Degree of Discomfort from Allergies

Not sure1%

Can't Tolerate38%

Can Ignore6%

Can Tolerate55%

Q17. In general, when you have a nasal allergy attack would you say that your discomfort is usually something you can ignore, you can’t ignore it, but you can tolerate it, or you can’t tolerate it without relief? Unweighted

N=2,500

21

What Triggers Allergy Symptoms

41%

34%

22%

22%

18%

11%

6%

6%

6%

5%

4%

0% 10% 20% 30% 40% 50%

Pollen

Dust

Grass

Weather

Animals

Dampness/Mold/Mildew

Perfume

Tobacco Smoke

Plants/Trees/Leaves

Fumes, odors

Chemicals

Q19. What things usually trigger or make your nasal allergy symptoms worse? Unweighted N=2,500

22

What Triggers Allergy Symptoms (cont.)

3%

2%

2%

1%

1%

1%

1%

1%

1%

6%

9%

0% 10% 20% 30% 40% 50%

Pollution

Food/Drink

Outdoors

Hay/Straw/Weeds

Insescts

Stress

Virus or Cold

Air quality/Dry heat/Air conditioning

Nothing

Other

Not Sure

Q19. What things usually trigger or make your nasal allergy symptoms worse? Unweighted N=2,500

23

Employment Status of Persons with Nasal Allergies

Homemaker7%

Disabled4%

Student5%

Unemployed3%Retired

19%

Part time9%

Full time53%

D6. Are you currently employed full-time, employed part-time, in the military, unemployed and looking for work, retired and not working, student, homemaker, disabled or too ill to work? Unweighted N=2,500

24

Do Nasal Allergies Keep from Working Full Time

Yes5%

No36%

Working full time53%

Retired6%

Q21a. Do your nasal allergies keep you from working full time? Unweighted N=2,500

25

Nasal Allergies Stop or Limit Working

Keep from working5%

Limit work9%No

80%

Retired6%

Q21a. Do your nasal allergies keep you from working full time? Q21b. Are you limited in the kind or amount of work you do because of your nasal allergies? Unweighted N=2,500

26

Missed Work due to Nasal Allergies

Yes30%

No70%

Q22a. Have you missed work in the past 12 months due to your nasal allergies? Base: Employed full time Unweighted N=1,315

27

Work Interference from Nasal Allergies

Neither48%

Both20%

Missed work only10%

Interfered only22%

Q22a. Have you missed work in the past 12 months due to your nasal allergies? Q23a. Aside from actually missing work, have your nasal allergy symptoms in the past 12 months interfered with your performance at work? Base: Employed full time Unweighted N=1,315

28

Work Interference due to Allergies

None1%

Little16%

Some28%

A lot20%Moderate

35%

Q23b. On days when you had nasal allergy symptoms how much did the symptoms interfere with your ability to do your job? Did the symptoms interfere a lot, a moderate amount, some, only a little, or not at all? Base: Full time, Interfered with work Unweighted N=547

29

Productivity and Allergies

95%

72%

0%

20%

40%

60%

80%

100%

No Symptoms Symptoms at worstQ24. Thinking about your productivity on a scale of 0 to 100, where 100 means 100% productivity, where would

you rank your productivity on days when you don’t have nasal allergy symptoms? Q25. Where would you rank your productivity on the same scale of 0 to 100 … when your nasal allergies are at their worst? Base: Employed full time Unweighted N=1,315

Mean Productivity

30

Exposed to Allergens at Workplace

Not sure2%

Yes58%

No40%

N26a. Are you exposed to anything at your workplace that affects your nasal allergy symptoms? Base: Full time and interferes at work. Unweighted N=511

31

Avoid Activities because of Allergies

Yes35%

No65%

Q27a. Do you avoid any activities because of your nasal allergies? Unweighted N=2,500

32

Symptoms During Worst Month

13%

26%

44%

8%

29%

23%

38%

36%

15%

36%

0%

20%

40%

60%

80%

100%

Depressed orblue

Irritable Tired Embarrassed Miserable

Sometimes

Frequently

Q30. During allergy season, how often do you feel (ITEM) – frequently, sometimes, rarely or never? Unweighted N=2,500

33

Impact of Allergies on Daily Life

Not sure1%

Didn't really impact14%

Little19%

Some26%

A lot15%

Moderate25%

Q31. During allergy season, would you say the condition impacted your daily life …..? Unweighted N=2,500

34

Nasal Allergy Control in Past Week

Not sure1%

Completely24%

Well controlled28%

Somewhat controlled33%

Not controlled5%

Poorly controlled 9%

Q32. Overall, how well would you say that your nasal allergies have been controlled in the last week? Would you say it was completely controlled, well controlled, somewhat controlled, poorly controlled, or not controlled at all? Unweighted N=2,500

35

Allergy Symptom Severity in Past Week

No symptoms23%

Mild symptoms36%

Severe11%

Moderate symptoms30%

Q33. How would you describe your nasal allergies during the last week? Would you say you had … no symptoms, mild symptoms, moderate symptoms, or severe symptoms? Unweighted N=2,500

36

Other Conditions in the Past Week

50%

23%

17%

16%

15%

10%

9%

2%

33%

0% 20% 40% 60% 80% 100%

Sinus problems

Heartburn or GERD

Cold or flu

Earaches

Migraines

Skin rashes

Fever

Pink eye

None of theseHad

Q37. During the last week have you had ………….? Unweighted N=2,500

37

Usual Source of Medical Care

1%

1%

2%

1%

1%

1%

3%

87%

5%

0% 20% 40% 60% 80% 100%

Doctor's office

Hospital outpatient clinic

Public Health clinic

Hospital ER

Company or Union clinic

Veteran's hospital/clinic

Clinic

Other

Not sure

Q41. Is the place that you usually go for your overall medical care, medical advice or treatment a……? Unweighted N=2,500

38

Primary Health Care Provider

Not sure1%

Other1%

Physician Asst4%

Doctor87%

Nurse Practitioner7%

Q41b. Who do you see most often for your health care, medical advice or treatment ……? Unweighted N=2,500

39

Specialty of Doctor Treating Nasal Allergies

30%

23%

12%

9%

6%

1%

1%

2%

0% 10% 20% 30% 40% 50%

General practice

Family practice

Internal medicine

Allergist

ENT

OB/GYN

Pulmonologist

Other

Q43. What is the medical specialty of the doctor that you see most often for your nasal allergies? Unweighted N=2,500

40

Seen Doctor for Nasal Allergies in Past 12 Months

No, not seen doctor, 52%

47%

1%

Q42a. Have you seen a health practitioner about your nasal allergies in the past 12 months? Unweighted N =2,500

41

Skin Test for Nasal Allergies

7%

5%

4%19%

66%

Q45a. Has your doctor or health practitioner ever given you a skin test to see what causes your nasal allergies? Q45b. When was the most recent time you had a skin test for your nasal allergies? Unweighted N =2,500

42

Blood Test for Nasal Allergies

7%2%

2%

6%

82%

QN46a. Has your doctor or health practitioner ever given you a blood test to see what causes your nasal allergies? QN46b. When was the most recent time you had a blood test for your nasal allergies? N =2,500

43

Shots for Nasal Allergies

9%

2%

2%

11%

75%

QN47a. Has your doctor or health practitioner ever given you nasal allergy shots? QN47b. When was the most recent time you had nasal allergy shots? Unweighted N =2,500

44

Drops or Extracts for Nasal Allergies

11%2%

1%

2%

83%

QN47c. Has your doctor or health practitioner ever given you nasal allergy drops or extracts by mouth or under the tongue to treat your nasal allergies? QN47d. When was the most recent time you had nasal allergy drops or extracts by mouth or under the tongue? Unweighted N =2,500

45

Shown How to Use Nasal Spray

2%

31%14%

8%

15%

30%

Q48a. Has a health practitioner ever shown you how to use a nasal spray for your nasal allergies? Q48b. When was the most recent time a health practitioner showed you how to use a nasal spray for your

nasal allergies? Unweighted N=2,500

46

Follow Health Practitioner’s Advice

1%

36%

41%

13%

4%

4%

Q49. Would you say that you follow your health practitioner’s advice on the management and treatment of your nasal allergies – all of the time, most of the time, some of the time, rarely or never? Unweighted N=2,500

47

Satisfaction with Health Practitioner’s Management of Your Allergies

57%

31%

2%

7%

3%

Q51. Overall, how satisfied are you with your health practitioner’s management and treatment of your nasal allergies? Unweighted N=2,500

48

Changed Doctors due to Dissatisfaction

87%

13%

Q52a. Have you ever changed doctors because you were dissatisfied with their management of your nasal allergies? Unweighted N=2,500

49

Seen Specialist for Nasal Allergies

14%

10%76%

Q54a. Have you seen a specialist about your nasal allergies in the past 12 months? Unweighted N=2,500

50

Satisfaction with Specialist’s Management of Your Allergies

5%

10%

22%

63%

1%

Q54c. Overall, how satisfied are you with your specialist’s management and treatment of your nasal allergies? Base: Seen specialist other than primary doctor in the past year. Unweighted N=265

51

Types of Medications Used for Allergies

28%27%

42%

3%

0%

10%

20%

30%

40%

50%

Prescription only Non-prescriptiononly

Both Neither

Q62. For the current management and treatment of your nasal allergy symptoms do you use prescription medications only, non-prescription medications only, or both? Unweighted N=2,500

52

Non-Prescription Medicine for Allergies in Past 4 Weeks

49% 51%

0%

20%

40%

60%

80%

100%

Yes No

Q63a. In the past 4 weeks, have you used any over-the-counter, non-prescription medicine to give you relief from nasal allergy symptoms? Unweighted N=2,500

53

Non-Prescription Medicine for Allergies: Recency of Use

54%

18%6%

5%

16%

Q63a. In the past 4 weeks, have you used any over-the-counter, non-prescription medicine to give you relief from nasal allergy symptoms? Q63b. When was the most recent time that you used an over the counter, non-prescription medicine for relief from nasal allergy symptoms? Unweighted N=2,500

54

Which OTC Medicine Used

22%

20%

17%

10%

6%

5%

3%

2%

2%

1%

1%

1%

36%

0% 10% 20% 30% 40% 50%

Claratin

Benadryl

Sudafed

Tylenol Allergy

Cold medicines

Afrin

Actifed

Alavert

Chloritrimenton

Tavist

Nasalcrom

Neo-Synephrine

Other

Q63c. What is the name of the over-the-counter medicines you take/took for nasal allergies? Base: Used in past 4 weeks. Unweighted N=1,345

55

Satisfaction with Recent OTC Medicine for Nasal Allergies

1%

41%

48%

7%

3%

Q63f. How satisfied are you with the over-the-counter medicine you used for your nasal allergies in the past 4 weeks? Base: Used OTC for nasal allergies in the past 4 weeks. Unweighted N=1,344

56

Prescription Nasal Spray for Allergies in Past 4 Weeks

34%

66%

0%

20%

40%

60%

80%

100%

Yes No

Q64a. In the past 4 weeks, have you used any prescription nasal spray for your nasal allergies? Unweighted N=2,500

57

Prescription Nasal Spray for Allergies: Recency of Use

36%

7%

14%

24%18% 1%

Q64a. In the past 4 weeks, have you used any prescription nasal sprays for your nasal allergies? Q64b. When was the most recent time that you used a prescription nasal spray for your nasal allergies? Unweighted N=2,500

58

Which Prescription Nasal Spray Used

41%

21%

14%

10%

5%

3%

9%

0% 10% 20% 30% 40% 50%

Flonase

Nasonex

Nasacort

Rhinocort

Astelin

Naserel

Other

Q64c. What is the name of the prescription nasal spray you take/took for nasal allergies? Base: Used in past 4 weeks. Unweighted N=919

59

How Many Symptoms Relieved by Nasal Spray

1%

3%

34%

46%

16%

Q65. Does your current prescription nasal spray give you relief from all of your symptoms, most symptoms, some symptoms, or no symptoms? Base: Use prescription nasal spray. Unweighted N=919

60

How Quickly Does it Relieve

37%

21%

8%

2% 1% 1%2%

12%

4%

0%

10%

20%

30%

40%

50%

Within 1hour

1 hour 2 hours 3-4hours

5-6hours

7-10hours

11-23hours

1-6 days Oneweek or

more

Q68. How long does it take for your current prescription nasal spray to begin giving you symptom relief? Unweighted N=919

61

Does Effectiveness Wear Off

7%

45%

48%

Q69a. Does your current prescription nasal spray lose effectiveness over the course of the day or night, or does it remain as effective as when you first took it? Base: Used prescription nasal spray Unweighted N=919

62

When Begins Losing Effectiveness

18%

32%

20%

17%

3%

5%

5%

0% 10% 20% 30% 40% 50%

Less than 4 hours

4-7 hours

8-11 hours

12-15 hours

16-23 hours

24 hours or longer

Not sure

Q69b. How long after taking your current nasal allergy medicine does it begin losing effectiveness? Base: Nasal spray loses effectiveness. Unweighted N=440

63

Satisfaction with Recent Rx Nasal Spray for Nasal Allergies

4%

6%

39%

49%

1%

Q70a. How satisfied are you with the prescription nasal spray you used for your nasal allergies in the past 4 weeks? Base: Used Rx nasal spray for nasal allergies in the past 4 weeks. Unweighted N=919

64

Satisfaction with Rx Nasal Sprays for Nasal Allergies

4%

34%

38%

12%

12%

Q70b. In general, how satisfied have you been with the prescription nasal spray you have used for your nasal allergies in the past? Base: Ever used Rx nasal spray for nasal allergies. Unweighted N=2,033

65

Reason for Not Using Rx Nasal Spray Recently

30%

11%

11%

11%

9%

8%

7%

6%

2%

2%

1%

1%

1%

1%

4%

0% 10% 20% 30% 40% 50%

No symptoms

Not bad enough

Not effective

Haven't seen doctor/Received prescription

Side effects

Don't like sprays

Don't like/Prefer other meds.

No insurance/Cost too high

Don't tolerate

Interferes with condition/meds.

Dependence concerns

Hard to use

Taste/Smell

Causes nosebleeds

Other

Q71. Why haven’t you used a prescription nasal spray you take/took for nasal allergies in the past 4 weeks? Base: Used in past but not past 4 weeks. Unweighted N=1,156

66

Other Prescriptions for Allergies in Past 4 Weeks

22%

77%

0%

20%

40%

60%

80%

100%

Yes No

Q72a. Have you taken any other prescription medications for your nasal allergies in the past 4 weeks? Unweighted N=2,500

67

Other Prescription Medicine Used

33%

26%

14%

9%

7%

1%

1%

24%

3%

0% 10% 20% 30% 40% 50%

Allegra

Zyrtec

Singulaire

Claritin Rx

Clarinex

Prednisone/Medroldose pack

Fexofenadine

Other

Not sure

Q72b. What is the name of the other prescription medicine you take/took for nasal allergies? Base: Used in past 4 weeks. Unweighted N=576

68

How Many Symptoms Relieved by Nasal Spray

22%

50%

23%

1%

2%

Q73. Does this prescription medicine give you relief from all of your symptoms, most symptoms, some symptoms, or no symptoms? Base: Use other prescription medicine. Unweighted N=576

69

How Quickly Does it Relieve

23%25%

14%

3%1% 1%

3%

10%

3%

0%

10%

20%

30%

40%

50%

Within 1hour

1 hour 2 hours 3-4hours

5-6hours

7-10hours

11-23hours

1-6 days Oneweek or

more

Q76. How long does it take for this prescription medicine to begin giving you symptom relief? Base: Use other prescription medicine. Unweighted N=576

70

Does Effectiveness Wear Off

6%

51%

42%

Q77a. Does this prescription medicine lose effectiveness over the course of the day or night, or does it remain as effective as when you first took it? Base: Use other prescription medicine. Unweighted N=576

71

When Begins Losing Effectiveness

9%

24%

29%

20%

7%

5%

5%

0% 10% 20% 30% 40% 50%

Less than 4 hours

4-7 hours

8-11 hours

12-15 hours

16-23 hours

24 hours or longer

Not sure

Q77b. How long after taking this nasal allergy medicine does it begin losing effectiveness? Base: Other prescription medicine loses effectiveness. Unweighted N=243

72

Satisfaction with Other Prescription Medicine for Nasal Allergies

1%

52%

38%

7%

3%

Q78. How satisfied are you with the other prescription medicine you used for your nasal allergies in the past 4 weeks? Base: Used other prescription medicine for nasal allergies in the past 4 weeks. Unweighted N=576

73

Medicine for Allergies in Past 4 Weeks

49%

34%

22%

44%

71%

29%

0%

20%

40%

60%

80%

100%

OTC Rx Nasal Spray Other Rx Any Rx Any Medication No Medication

Q63a. In the past 4 weeks, have you used any over-the-counter, non-prescription medicine to give you relief from nasal allergy symptoms? Q64a. In the past 4 weeks, have you used any prescription nasal spray for your

nasal allergies? Q72a. Have you taken any other prescription medications for your nasal allergies in the past 4 weeks? Unweighted N=2,500

74

Use of Prescription Meds for Nasal Allergies

31%

51%

17%

1%

0%

20%

40%

60%

80%

100%

All year Only Part Year Never take Not sure

Q79. Do you take prescription medicines for your nasal allergies all through the year or only during the times of the year that your nasal allergies are the worst? Unweighted N=2,500

75

Change Prescription Medicines for Nasal Allergies

10%

2%

8%

12%

38%

29%

Q81a. How often do you change nasal allergy medicines ---several times each year, once a year, every few years, only rarely or never? Unweighted N=2,500

76

Why Changed Medicine for Nasal Allergies

37%

23%

11%

8%

5%

4%

3%

3%

3%

3%

2%

2%

2%

1%

3%

4%

0% 10% 20% 30% 40% 50%

Not effective enough

Doctor wanted to try other

Patient wanted to try other

Bothersome side effects

Cost/co-pay

Didn't treat symptoms

Not covered

Safety concerns

Developed an immunity

Availability/ Convenience/ Free samples

Not long lasting enough

Taken off market

Haven't changed allergy medicines

Not fast enough

Not sure

Other

Q81b. Why have you changed nasal allergy medicines? Anything else? Base: Have changed nasal allergy medicines. Unweighted N=1,723

77

Asked Doctor to Change Medication

66%

34%

Q82a. Have you ever asked your doctor to change your nasal allergy medication because you were dissatisfied with it? Unweighted N=2,500

78

Why Dissatisfied with Nasal Allergy Medicine

66%

21%

12%

10%

1%

1%

1%

4%

2%

0% 20% 40% 60% 80% 100%

Wasn't effective

Bothersome side effects

Effectiveness wore off

Didn't provide 24 hour relief

Not covered

Cost/co-pay

Hard to administer

Other

Not sure

Q82c. Why were you dissatisfied with that medicine? Base: Have asked doctor to change nasal allergy medicines. Unweighted N=860

79

How Quickly Supposed to Relieve

47%

17%

4%

1%

1%

4%

10%

15%

0% 10% 20% 30% 40% 50%

Within 1 hour

1-3 hours

4-6 hours

7-9 hours

10-12 hours

13-24 hours

25 hours or longer

Not sure

Q85. How quickly are prescription medicines supposed to begin providing symptom relief for nasal allergies? Unweighted N=2,500

80

How Long Supposed to Relieve

10%

19%21%

4%

30%

16%

0%

10%

20%

30%

40%

50%

Less than 6hours

6-11 hours 12-17 hours 18-23 hours 24 hours orlonger

Not sure

Q86. How long are prescription medicines supposed to provide symptom relief for nasal allergies? Unweighted N=2,500

81

Effectiveness Ever Wore Off before 24 Hours

9%

33%

58%

Q87a. Have you ever found that the effectiveness of a product that promised 24 hour relief began wearing off earlier? Unweighted N=2,500

82

Effectiveness Wore Off: Multiple Products

9%

33%

4%

16%

39%

Q87a. Have you ever found that the effectiveness of a product that promised 24 hour relief began wearing off earlier? Q87b. Has this happened with more than one nasal allergy product? Unweighted N=2,500

83

When Does Effectiveness Wear Off

3%2%

3%

15% 15%

19% 19%

25%

0%

10%

20%

30%

40%

50%

Within 1hour

1 hour 2 hours 3-4 hours 5-6 hours 7-10 hours 11 or more Not sure

Q87c. About how long after you started taking it does a nasal allergy medicine’s effectiveness begin wearing off? Base: Found nasal allergy medicine offering 24 hour relief wearing off. Unweighted N=1,461

84

Stopped Taking Because Effectiveness Wore Off

33%

57%

0%

20%

40%

60%

80%

100%

All Patients Unweighted N=2,500 Experienced Wear-off Unweighted N=1,461

Q87d. Have you ever stopped taking a product for your nasal allergies because its effectiveness had worn off?

85

Effectiveness Wears Off Over Time

6%

40%

2%

15%

38%

Q88a. Have you ever found that a product’s effectiveness in treating your nasal allergy symptoms wears off over time even when you are taking the medicine as prescribed? Q88b. Has this happened to you with more

than one nasal allergy product? Unweighted N=2,500

86

When Does Effectiveness Wear Off

12%

7% 6%

13% 13%

10%12%

27%

0%

10%

20%

30%

40%

50%

Within 1month

1 month 2 months 3-4 months 5-6 months 7-10 months 11 or moremonths

Not sure

Q88c. About how long after you started taking it does a nasal allergy medicine’s effectiveness begin wearing off even when taken as prescribed? Base: Found nasal allergy medicine wearing off. Unweighted N=1,364

87

Stopped Taking Because Effectiveness Wore Off

36%

66%

0%

20%

40%

60%

80%

100%

All Patients Unweighted N=2,500 Experienced Wear-off Unweighted N=1,364

Q88d. Have you ever stopped taking a product for your nasal allergies because its effectiveness had worn off?

88

Nasal Allergy Meds Cause Nosebleeds

2%

20%

78%

Q89a. Have any of the medicines that you have taken for your nasal allergy ever caused nosebleeds? Unweighted N=2,500

89

How Bothersome were Nosebleeds

1%8%

32%

28%

31%

Q89b. How bothersome were those nosebleeds? Base: Medicine caused nosebleeds. Unweighted N=501

90

Side Effects of Allergy Medicines

8%

3%

11% 10%

2% 4%

7%

3%

8%12%

7%

17%

11%

22%

25%

12%

26%

2%

0%

10%

20%

30%

40%

50%

Bad taste Burning Drippingdown throat

Drying feeling Headaches Drowsiness

Some

Most

All

Q90. How many of the medicines that you have taken for allergy had the following types of side effects --- all, most, some, few or none? Unweighted N=2,500

91

How Bothersome are Side Effects

7% 7%

13% 12% 12% 12%

15%

11%

20% 22%

13%

21%

0%

10%

20%

30%

40%

50%

Bad taste Burning Dripping downthroat

Drying feeling Headaches Drowsiness

Moderately

Extremely

Q91. How bothersome are the following side effects of nasal allergy medicines --- extremely, moderately, slightly or not bothersome? Unweighted N=2,500

92

Try to Avoid Certain Medicines

1%

62%

36%

Q100a. Are there any nasal allergy medications that you try to avoid using? Unweighted N=2,500

93

Reason Stopped Taking Nasal Allergy Prescription

37%

35%

32%

25%

14%

11%

4%

3%

39%

0% 10% 20% 30% 40% 50%

Didn't find it effective

Effectiveness began wearing off

Didn't provide 24 hour relief

Bothersome side effects

Not covered

Co-pay was too high

Dosing schedule was difficult

Hard to administer

None of these

Q94. Have you ever stopped taking a nasal allergy medicine prescribed by your doctor because…. Unweighted N=2,500

94

Tell Doctor when Stop Taking Rx Meds

1%

51%

48%

Q95. When you have stopped taking a nasal allergy medicine for one of these reasons, do you always tell your doctor right away? Base: Have stopped taking nasal allergy medicine prescribed by doctor. Unweighted N=1,490

95

Get Money’s Worth from Rx Meds

10%

55%

34%

Q97. Overall, do you feel that patients get their money’s worth out of prescription medicines for nasal allergies? Unweighted N=2,500

96

Most Important for Nasal Allergy Medicine

17%

32%

37%

2%

6%

5%

1%

0% 10% 20% 30% 40% 50%

Fast symptom relief

Long lasting relief

Complete symptom relief

Easy to take

Few side effects

Low cost

Not sure

Q98. In choosing a nasal allergy medicine, which would be the most important to you …? Unweighted N=2,500

97

Important for Nasal Allergy Medicine

17%

32%

37%

6%

5%

22%

30%

15%

13%

13%

2%

1%

4%

1%

0% 20% 40% 60% 80% 100%

Fast symptom relief

Long lasting relief

Complete symptomrelief

Easy to take

Few side effects

Low cost

Not sure

Most Next

Q98. In choosing a nasal allergy medicine, which would be the most important to you …? Q99. What would be the next most important to you? Unweighted N=2,500

98

How Many Symptoms Relieved for Success

1%

1%4%

8%53%

33%

Q101. How many symptoms would a nasal allergy medicine have to relieve for you to consider it a successful treatment --- all, most, some, a few or none? Unweighted N=2,500

99

Percent Relief for Success

86%84% 85%

83%85%

0%

20%

40%

60%

80%

100%

All Patients N=2,500 No symtoms Mild symptoms Moderate symptoms Severe symptoms

Q102. On a scale of 0 to 100 percent, what percent symptom relief would you expect from a nasal allergy medicine for it to be considered a successful treatment? Q33. How would you describe your nasal allergy symptoms in the past week?

100

How Quickly Must Relieve

43%

27%

10%

4%

1%

1%

8%

5%

0% 10% 20% 30% 40% 50%

Within 1 hour

1 hour

2 hours

3-4 hours

5-6 hours

7-10 hours

11 hours or longer

Not sure

Q103. How quickly after taking would a nasal allergy medicine have to begin relieving symptoms for you to consider it a successful treatment? Unweighted N=2,500

101

How Long Must Last

5%

18%

18%

24%

5%

27%

3%

0% 10% 20% 30% 40% 50%

Less than 4 hours

4-7 hours

8-11 hours

12-15 hours

16-23 hours

24 hours or longer

Not sure

Q104. How long after you take a dose of nasal allergy medicine should symptom relief last for you to consider it a successful treatment? Unweighted N=2,500

102

Failed to Follow Physician Instructions

41%

37%

35%

27%

22%

21%

19%

19%

3%

0% 10% 20% 30% 40% 50%

Lack of symptom relief

Loss of effectiveness overtime

Lack of symptoms

Troublesome side effects

Worry about side effects

Cost of drugs

Concern about long termuse

Poor toleration

Doctor's instructions hardto follow

Q108. People with nasal allergies sometimes fail to follow their physician’s instructions about their medicines for allergies. Have you ever failed to take an allergy medicine as prescribed because of ……

Unweighted N=2,500

103

Allergies Impact on Activities with Children

87%

3%

10%

Q109b. Do your nasal allergies interfere with activities that you would like to do with the children? Q109c. Do your nasal allergies ever make you feel guilty when they interfere with activities with the children? Base: Children under 18 Unweighted N=882

104

Attitudes about Nasal Allergies

55%

28%

15%

22%

56%

64%

29%

43%

20%

36%

19%

21%

0% 20% 40% 60% 80% 100%

Nasal allergies are serioushealth problem in US

Nasal allergies usuallycause some lifestyle

limitations

There are no truly effectivetreatments for nasal

allergies

Frequent nasal allergysymptoms can be

prevented

Nasal allergies can makeasthma worse

Nasal allegies can causesinus infections

Agree strongly

Agree somewhat

Q110. Now I am going to read you a series of statements. As I read each statement , please tell me whether you agree strongly, agree somewhat, disagree somewhat or disagree strongly with the statement. Unweighted N=2,500

105

Source of Health Insurance

67%

14%

14%

5%

3%

2%

1%

11%

0% 20% 40% 60% 80% 100%

Through work, school orunion

Bought directly by you

Medicare

Medicaid

Military/VA/Champus

Other

Not sure

Not covered

Q111a. Do you have any sort of health insurance or health plan to cover your health care costs? Q111c. Is your coverage under that/those plans from ….. Unweighted N=2,500

106

How Much of Prescription Drug Costs Covered

11%

3%

4%

3%19%

50%

10%

Q111d. How much of the costs of your prescription drugs is covered by your health plan --- all, most, some, little or none? Unweighted N=2,500

107

Insurance Restricts Type Of Medicine

10%

59%

20%

11%

Q111f. Does your insurance restrict your doctor from prescribing specific nasal allergy medications for you? Unweighted N=2,500

108

Need for Patient Education

49%

40%

7%

2%

3%

Q113. How much need do you think there is for better education of people with nasal allergies about their condition and its treatment? Unweighted N=2,500

109

Family History of Nasal Allergies

27%

37%

49%

46%

13%

17%

2%

0% 20% 40% 60% 80% 100%

Father

Mother

Brothers or sisters

Children

Grandparents

None of these

Not sure

Q116. Do any of the following relatives of yours have nasal allergies? Unweighted N=2,500

110

Pets in the Household

40%

28%

3%

2%

1%

1%

2%

44%

0% 10% 20% 30% 40% 50%

Dog

Cat

Bird

Fish

Hamster/gerbil

Rabbit

Other

No pets in house

Q117a. Do you have any pets living in your house? Q117b. What kind of pet or pets? Unweighted N=2,500

111

Smokers in Household

76%

24%

Q118a. Does anyone in your household smoke? Unweighted N=2,500

Allergies in America: Survey of Health Professionals

Conducted bySchulman, Ronca & Bucuvalas, Inc.

February 28, 2006

Conducted bySchulman, Ronca & Bucuvalas, Inc.

February 28, 2006

Supported by:

113

Study Design

Population Sampling Frame Interview LengthCompleted Sample

Population Aged 18+ National RDD 34.8 minutes 2,500

Cross-section: 1/5/06-1/31/06

Health Professional Survey-- Adult Primary Care-- Allergy-- Otolaryngology-- Nurse practitioner-- Physician assistant

AMA/AOA Master List

19.4 minutes

100100100 50 50

Physician Survey: 1/17/06-2/14/06

114

Health Provider Type

25% 25% 25%

13% 13%

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

ENT Allergist Primary care NursePractitioner

Physician Asst

Base: Total completed interviews N=400

115

Primary Ambulatory Care Setting

1%

45%

44%

1%

41%

25%

22%

6%

4%

1%

1%

19%

18%

16%

34%

2%

6%

4%

2%

2%

17%

44%

34%

10%

0% 5% 10% 15% 20% 25% 30% 35% 40% 45% 50%

Solo practice

Single-specialtygroup

Multi-specialty group

Clinic

HMO

Hospital Outpatient

Other Nurse Prac./Physician Asst.Primary careAllergistENT

Q3. In what type of ambulatory care setting do you spend MOST of your (out-patient) patient care time during a usual work week? Is it… N=400

116

Patients Seen on Outpatient Basis

80

97

113

103

0

20

40

60

80

100

120

ENT Allergist Primary Care NursePrac./Physician

Asst

Q4. In an average week, about how many patients do you see on an outpatient basis? N=400

Wee

kly

aver

age

117

Percent of Patients with Rhinitis

22%22%

64%

33%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care NursePrac./Physician

Asst

Q5. About what percent of the outpatients you see each week have allergic rhinitis? N=400

Wee

kly

aver

age

118

How Bothersome are Symptoms

81%

73%

77%10%

8%

26%

16%

84%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Extremely Moderately

Q6. For most patients that you see with allergic rhinitis, how bothersome are their nasal allergy symptoms? Would you say they are extremely bothersome, moderately bothersome, slightly bothersome or not bothersome? N=400

119

Most Bothersome Symptoms

96%

53%

50%

73%

98%

45%

57%

74%

78%

90%

46%

51%

63%

72%

90%

10%

5%

10%

14%

22%

75%

68%

45%

37%

69%

0% 20% 40% 60% 80% 100%

Red/Itching eyes

Watery eyes

Runny nose

Post-nasal drip

Nasal congestion

Patients (single choice)

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

Q7. Which of the following nasal allergy symptoms are most bothersome to your patients? N=400PQ16. Which of these symptoms was the most bothersome to you? Base: Had bothersome symptoms.

Unweighted N=2,362

120

Most Bothersome Symptoms (Cont.)

55%

31%

41%

42%

41%

4 1%

3 9%

3 9%

3 3%

4 8%

31%

30%

29%

36%

37%

4%

4%

9%

14%

7%

50%

31%

37%

45%

47%

0% 20% 40% 60% 80% 100%

Ear pain

Itching

Repeated sneezing

Headache

Facial pain

Patients (single choice)

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

Q7. Which of the following nasal allergy symptoms are most bothersome to your patients? N=400PQ16. Which of these symptoms was the most bothersome to you? Base: Had bothersome symptoms.

Unweighted N=2,362

121

Discomfort During Allergy Attack

45%

60%

44%

45%

38% 55%

55%

55%

38%

55%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

Can't tolerate Can't ignore

Q8. In general, would you say that patients’ discomfort during a nasal allergy attack is usually something they can ignore, they can’t ignore it, but they can tolerate it, or they can’t tolerate it without relief? N=400

PQ17. In general, when you have a nasal allergy attack would you say that your discomfort is usually something you can ignore, you can’t ignore it, but you can tolerate it, or you can’t tolerate it without relief? Unweighted

N=2,500

122

Patients Missing Work due to Rhinitis

19%

19%

13%

23%

32%

27%

30%

3%

3%

14%

40%

0% 10% 20% 30% 40% 50% 60% 70%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients (yes)

All (91% to 100%) Most (51% to 90%) Some (11% to 50%)

Q9. Among your patients with allergic rhinitis who are employed, how many would you estimate have missed work in the past 12 months due to their nasal allergies? N=400

PQ22a. Have you missed work in the past 12 months due to your nasal allergies? Base: Employed full time Unweighted N=1,315

123

Productivity when Nasal Allergies are at Their Worst

72%

62%64%60%

65%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care Nurse Prac./Physician Asst

Patients

Q10. Thinking about productivity at work on a scale from 0 to 100, where 100 means 100% productivity, where would you rank the productivity of persons with allergic rhinitis, when their nasal allergies are at their worst? N=400

PQ24. Thinking about your productivity on a scale of 0 to 100, where 100 means 100% productivity, where would you rank your productivity on days when you don’t have nasal allergy symptoms? PQ25. Where would you rank your productivity on the same scale of 0 to 100 … when your nasal allergies are at their worst? Base: Employed full time Unweighted N=1,315

Wee

kly

aver

age

124

Impact of Allergies on Daily Life

15%

62%

44%

47%

25%

34%

18%

47%

30%

63%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

A lot Moderate

Q11. For the average patient with allergic rhinitis, during allergy season, would you say the condition impacted their daily life a lot, impacted their daily life a moderate amount, impacted their daily life some, impacted their daily life a little, or does not really impact their daily life? N=400

PQ31. During allergy season, would you say the condition impacted your daily life …..? Unweighted N=2,500

125

Classification of Nasal Allergies

41%

61%

71%

60%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care NursePrac./Physician

Asst

Q12. Do you classify the severity of nasal allergies in patients [DOCTOR VERSION: when you make the diagnosis] [PA/NP VERSION: when you initially see them]? N=400

Wee

kly

aver

age

126

Percent of Patients with Seasonal Allergies

43%

57%55%

39%

49%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care Nurse Prac./Physician

Asst

Patients

Q13a. What proportion of your patients with nasal allergies would you classify as having seasonal rather than perennial allergies? N=400

PQ12. Would you describe your nasal allergies as seasonal or do they occur throughout the year? Unweighted N=2,500

Wee

kly

aver

age

127

Proportion of Patients Classified by Symptom Severity

46%

45%

41%

27%

34%

34%26%

23%

35%

28%

42%

20%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Severe Moderate Mild

Q13b. What proportion of your patients with nasal allergies would you classify as having…? N=400

128

Skin Test to Confirm Diagnosis

49%

27%

39%

43%

27%

25%3%

3%

56%

3%

3%

2%

4%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients (yes)

Always Most of the time Sometimes

Q14. How often do you conduct a skin test, either in your office or by referral, when making or confirming a diagnosis of allergic rhinitis…? N=400

PQ6a. Were you given a skin test to see what you were allergic to? Unweighted N=2,500

129

Blood Test to Confirm Diagnosis

23%

12%

3%

28%

27%

19%1%

2%

1%

3%

1%

5%

33%

0% 10% 20% 30% 40% 50%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients (yes)

Always Most of the time Sometimes

Q15. How often do you conduct a blood test, either in your office or by referral, when making or confirming a diagnosis of allergic rhinitis…? N=400

PQ6b. Were you given a blood test to see what you were allergic to? Unweighted N=2,500

130

Allergy Shots to Treat Nasal Allergies

25%

18%

36%

10%

44%

35%

27%4%

9%

9%

13%

3%

44%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients (ever)

All Most Some

Q16. Among your patients with allergic rhinitis, do you give allergy shots to or refer patients to get allergy shots to treat nasal allergies to all, most, some, a few or none? N=400

PQN47a. Has your doctor or health practitioner ever given you nasal allergy shots? Unweighted N =2,500

131

Allergy Drops to Treat Nasal Allergies

17%

3%

7%

13%

12%

8%

2%

4%

3%

1%

3%

6%

0% 5% 10% 15% 20% 25% 30%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients (ever)

All Most Some

Q17. Among your patients with allergic rhinitis, do you give or refer patients to get allergy drops or extracts by mouth or under the tongue to treat nasal allergies to all, most, some, a few or none? N=400

PQN47c. Has your doctor or health practitioner ever given you nasal allergy drops or extracts by mouth or under the tongue to treat your nasal allergies? Unweighted N =2,500

132

How Often Show How to Use Nasal Spray

31%

4%

3%

3%

22%

64%

55%

72%

73%

15%

15%

15%

40%

22%

1%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

At least once a year Every few years When first prescribed/5 years or more

Q18. How often do you show patients how to use a nasal spray for their nasal allergies? N=400PQ48a. Has a health practitioner ever shown you how to use a nasal spray for your nasal allergies? PQ48b.

When was the most recent time a health practitioner showed you how to use a nasal spray for your nasal allergies? Unweighted N=2,500

133

How Often Patients Follow Advice

36%

1%1%1%

67% 70%

57%

39%

41%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

Most of the time

All of the time

Q19. Would you say that most of your patients with allergic rhinitis follow your advice on the management and treatment of nasal allergies…? N=400

PQ49. Would you say that you follow your health practitioner’s advice on the management and treatment of your nasal allergies – all of the time, most of the time, some of the time, rarely or never? Unweighted N=2,500

134

Percent of Patients Very Satisfied With Disease Management

78%87%

62%

57%

3%4%3%

72%

8%

31%

17%28%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

All (91% to 100%) Most (51% to 90%) Some (11% to 50%)

Q20. Approximately, what proportion of your patients with nasal allergies would you say are VERY satisfied with the management of their disease? Would you say… N=400

PQ51. Overall, how satisfied are you with your health practitioner’s management and treatment of your nasal allergies? Unweighted N=2,500

135

Effect of Medical Treatment on Quality of Life

34%

26%

41%51%

46%

74%

60%

42%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

A lot Moderate

Q21. How much effect does medical treatment have on the quality of life for an adult with allergic rhinitis? N=400

136

How Often Patients Change Allergy Medications

10%

29%

34%

25%

8%

38%

29%

39%

35%

12%

12%

19%

20%

17%

38%

20%

13%

17%

21%

28%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

Several times a year Once a year Every few years Rarely

Q22. How often do your patients with allergic rhinitis change allergy medicines – sever times each year, once a year, once every few years, only rarely or never? N=400

PQ81a. How often do you change nasal allergy medicines ---several times each year, once a year, every few years, only rarely or never? Unweighted N=2,500

137

Patients Ask to Change Allergy Medicine

16%

51%

63%

56%

34%

1%

1%

1%

1%

13%

9%

5%

61%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients (yes)

All (91% to 100%) Most (51% to 90%) Some (11% to 50%)

Q23a. What proportion of your patients with allergic rhinitis have asked you to change their allergy medication because they were dissatisfied with it – all, most , some, only a few or none? N=400

PQ82a. Have you ever asked your doctor to change your nasal allergy medication because you were dissatisfied with it? Unweighted N=2,500

138

Reasons for Dissatisfaction with Medicine

3 5%

9%

1 1%

6%

5 3%

8 7%

5%

9%

1 3%

1 3%

3 3%

7 8%

8%

6%

8%

2 0%

3 1%

6 9%

1 0%

1%

1%

1 2%

2 1%

6 6%

8 2%

1 9%

1 1%

7%

1%

1 1%

0% 20% 40% 60% 80% 100%

No relief throughday/night

Co-pay too high

Not covered byinsurance

Effectiveness wearsoff

Bothersome sideeffects

Not effective

Patients

Nurse Prac./Physician Asst.Primary care

AllergistENT

Q23b. Why are patients dissatisfied with their allergy medicine? [Unaided question] Base: Have asked to change medicine because dissatisfied N=395

PQ82c. Why were you dissatisfied with that medicine? Base: Have asked doctor to change nasal allergy medicines. Unweighted N=860

139

Reasons for Dissatisfaction with Medicine (cont.)

2%

1%

2%

2%

2%

3%

1%

2%

1%

1%

1%

4%

2%

3%

2%

5%

2%

4%

1%

4%

1%

1%

1%

1%

1%

1%

1%

0% 20% 40% 60% 80% 100%

Other

Hard to administer

Dosing scheduledifficult

Cost/Expensive

Don't like nasal spray

Doctor wanted toswitch

Wanted to trysomething else

Patients

Nurse Prac./Physician Asst.Primary care

AllergistENT

Q23b. Why are patients dissatisfied with their allergy medicine? [Unaided question] Base: Have asked to change medicine because dissatisfied N=395

PQ82c. Why were you dissatisfied with that medicine? Base: Have asked doctor to change nasal allergy medicines. Unweighted N=860

140

Most Important Attribute of Allergy Medicine

1%

2 0%

3 0%

5%

2%

1%

2 8%

1 9%

4 3%

2%

4%

4%

1 3%

2 6%

3 8%

3%

3%

1 7%

1 7%

3 2%

3 7%

2%

6%

5%

1%

1%

4 2%

2 4%

3 1%

4 1%

0% 20% 40% 60% 80% 100%

Fast symptom relief

Long lasting symptomrelief

Complete symptomrelief

Easy to take

Few side effects

Low cost

Patients

Nurse Prac./Physician Asst.Primary care

AllergistENT

Q38. In choosing a medicine for nasal allergies, which would be most important to your patients? N=400PQ98. In choosing a nasal allergy medicine, which would be the most important to you …? Unweighted N=2,500

141

Most Important Attributes of Allergy Medicine

1 6%

3 9%

5 1%

1 6%

2 5%

8%

4 8%

5 2%

4 9%

1 3%

1 6%

2 2%

3 3%

4 3%

4 8%

1 6%

1 9%

3 9%

3 9%

6 2%

5 2%

6%

1 9%

1 8%

2 9%

1 3%

5 4%

3 9%

4 9%

6 1%

0% 20% 40% 60% 80% 100%

Fast symptom relief

Long lasting symptomrelief

Complete symptomrelief

Easy to take

Few side effects

Low costPatients

Nurse Prac./Physician Asst.Primary care

AllergistENT

Q38. In choosing a medicine for nasal allergies, which would be most important to your patients? Q39. What would be next most important to your patients? N=399

PQ98. In choosing a nasal allergy medicine, which would be the most important to you …? PQ99. What would be the next most important to you? Unweighted N=2,500

142

Preferred Medicines for Moderate to Severe Persistent Allergy Symptoms

9%

61%

1%

3%

10%

11%

5%

57%

4%

3%

6%

7%

4%

16%

37%

54%

8%

2%

5%

6%

9%

17%

41%

53%

39%

16%

5%

4%

6%

5%

28%

4%

0% 20% 40% 60% 80% 100%

Non sedating antihistamines

Oral antihistamines

Internasal antihistamines

Antichol. Nasal spray

Antihis./decon. RX

Antihis. OTC

Antihis. RX

Inhaled Corticosteroids

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

Q31. What class or classes of medication is your preferred choice for adults with moderate to severe persistent allergy symptoms? [Unaided response] N=400

143

Preferred Medicines for Moderate to Severe Persistent Allergy

Symptoms (cont.)

1 %

1 0%

9%

1%

2%

2%

1 5 %

5%

4%

4%

4%

4%

7%

5%

1%

1%

1%

3%

5%

7%

2%

2%

1%

4%

3%

1%

0% 20% 40% 60% 80% 100%

Other

Cromolyn

Decongestant nasal spray OTC

Leukotrienes

Antihis./decon. OTC

Decon. OTC

Medication names

Nasal steroids

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

Q31. What class or classes of medication is your preferred choice for adults with moderate to severe persistent allergy symptoms? [Unaided response] N=400

144

Patients Using Intra-Nasal Corticosteroids

36%

54%58%

72%72%

14%

7%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

Past 4 weeks Past 6 months Past year

Q32. What proportion of your patients with allergic rhinitis are currently using an intra-nasal corticosteroid for their condition? N=400

PQ64a. In the past 4 weeks, have you used any prescription nasal sprays for your nasal allergies? PQ64b. When was the most recent time that you used a prescription nasal spray for your nasal allergies? Unweighted N=2,500

145

Symptoms Relieved by Intra-nasal Corticosteroids

70%80%

73% 46%

16%

1%4%

72%

34%

19%25%30%

23%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

All Most Some

Q33. Do intra-nasal corticosteroids give most patients relief from all of their symptoms, most symptoms, some symptoms, few symptoms, or no symptoms? N=400

PQ65. Does your current prescription nasal spray give you relief from all of your symptoms, most symptoms, some symptoms, or no symptoms? Base: Use prescription nasal spray. Unweighted N=919

146

Time for Intra-nasal Corticosteroids Relief

71%

53%

63%

43%

12%

35%

17%

24%

35%

4%

14%

23%

18%

11%

50%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

Hours Days Weeks

Q34. How long does it take an intra-nasal corticosteroid to begin giving symptoms relief? N=400PQ68. How long does it take for your current prescription nasal spray to begin giving you symptom relief?

Unweighted N=919

147

How Long Intra-nasals Provide Relief

Q25. How long are intra-nasal corticosteroids supposed to provide symptoms relief for nasal allergies? N=400

6 1%

6 4%

8 4%

6 7%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care NursePrac./Physician

Asst.

24 h

ou

rs o

r lo

ng

er

148

Do Intra-nasals Lose Effectiveness

48%

29%

37%

25%

48%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

Q35a. Do intra-nasal corticosteroids lose effectiveness over the course of the day or night, or do they remain as effective as when the patient first took it? N=400

PQ69a. Does your current prescription nasal spray lose effectiveness over the course of the day or night, or does it remain as effective as when you first took it? Base: Used prescription nasal spray Unweighted N=919

Yes

149

Time Until Intra-nasals Lose Effectiveness

Q35b. How long after taking an intra-nasal corticosteroid does it begin losing effectiveness allergies? Base: Lose effectiveness over day and night N=139

PQ69b. How long after taking your current nasal allergy medicine does it begin losing effectiveness? Base: Nasal spray loses effectiveness. Unweighted N=440

5%

21%

30%32%

25%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

24 h

ou

rs o

r lo

ng

er

150

Intra-Nasal Corticosteroids Wear Off Over Time

Q27a. Have you ever found that the effectiveness of intra-nasal corticosteroid products in treating nasal allergy symptoms wears off over time, even when taking the medicine as prescribed? N=400

54%54%50%

55%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care NursePrac./Physician

Asst

Yes

151

Time Until Intra-nasal Corticosteroids Wear Off

7%

16%

4%

56%

36%

54%

48%

16%

26%

17%

26%

11%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Hours Days Weeks

Q27b. About how long after the patient starts taking an intra-nasal corticosteroid does its effectiveness for allergy symptoms begin wearing off, even when being taken as prescribed? Base: Effectiveness wears off N=213

152

Side Effects of Intranasal Corticosteroids

Q28. How many of the intranasal corticosteroids for nasal allergies have the following types of side effects – all, most, some, few or none? N=400

5%

4%

10%

1%

20%

12%

42%

20%

2%

5%

31%

13%

45%

18%

6%

2%

19%

34%

3%

20%

38%

0% 20% 40% 60% 80% 100%

Bad taste

Burning

Dripping down throat

Drying feeling

Headaches

Drowsiness

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

153

Patients Avoid Any Intra-Nasal Corticosteroids

31%35%

24%

18%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care NursePrac./Physician

Asst

Q29a. Are there any intranasal corticosteroid medications for nasal allergies that your patients try to avoid using? N=400

Yes

154

Reasons Avoid Intranasal Corticosteroids by Specialty

10%

6%

5%

4%

3%

3%

3%

2%

2%

2%

2%

2%

8%

7%

7%

13%

15%

19%

36%

0% 20% 40% 60% 80% 100%

Smell/bad odor or smell/Taste

Nosebleeds

Burning/stinging

Side effects (not specified)

Spray up nose

Drying/Dried out

Price/cost

Don't work

Medication only mentioned

Dripping down throat

Headaches

Steroids

Not covered by insurance

Drowsiness/sleepy/tired/fatigue

Absorbs into system

Bad experience

Don't like it/causes discomfort

Don't understand/fear

Other

Q29b. Why do your patients try to avoid that/those product(s)? N=108

155

Satisfaction of Patients with Intra-nasal Corticosteroids

34%

54%

61%

55%

38%

41%

41%

39%

42%

57%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

Very satisfied Somewhat satisfied

Q36. In general, how satisfied are your allergic rhinitis patients with their intra-nasal corticosteroids? Would you say that they are very satisfied, somewhat satisfied, somewhat dissatisfied, or very dissatisfied? N=400

PQ70b. In general, how satisfied have you been with the prescription nasal spray you have used for your nasal allergies in the past? Base: Ever used Rx nasal spray for nasal allergies. Unweighted N=2,033

156

Patients Avoid Using Intra-Nasal Corticosteroids for Nasal Allergies

Q37a. Do patients avoid using intra-nasal corticosteroids for their nasal allergies? N=400

42%40%

55%

41%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary Care NursePrac./Physician

Asst

Yes

157

Reasons Avoid Intra-nasal Corticosteroids

22%

54%

5%

4%

5%

18%

29%

55%

8%

8%

10%

15%

30%

30%

45%

12%

5%

2%

2%

10%

40%

57%

1%

6%

11%

1%

9%

8%

29%

20%

2%

7%

2%

2%

29%

2%

0% 20% 40% 60% 80% 100%

Taste/smell

No insurancecoverage/cost too much

Not effective

Other side effects

Nosebleeds

Safety

Side effects

Don't like sprays

Patients

Nurse Prac./Physician Asst.Primary care

AllergistENT

Q37b. Why do they avoid using intra-nasal corticosteroids for their nasal allergies? Base: Avoid using intra-nasal corticosteroids for nasal allergies N=178

PQ71. Why haven’t you used a prescription nasal spray you take/took for nasal allergies in the past 4 weeks? Base: Used in past but not past 4 weeks. Unweighted N=1,156

158

Reasons Avoid Intra-nasal Corticosteroids (cont.)

2%

2%

4%

4%

2%

4%

3%

3%

5%

2%

7%

5%

5%

1%

1%

30%

2%

11%

4%

2%

2%

5%

2%

4%

0% 20% 40% 60% 80% 100%

Dependence worry

Hard to use

No symptoms

Don't tolerate well

Not bad enough

Too drying

Timing/frequency of use

Don't give immediate relief

Other

Patients

Nurse Prac./Physician Asst.Primary care

AllergistENT

Q37b. Why do they avoid using intra-nasal corticosteroids for their nasal allergies? Base: Avoid using intra-nasal corticosteroids for nasal allergies N=178

PQ71. Why haven’t you used a prescription nasal spray you take/took for nasal allergies in the past 4 weeks? Base: Used in past but not past 4 weeks. Unweighted N=1,156

159

Number of Symptoms Relieved for Success

33%

76%

75%

76%

53%

7%

6%

6%

4%

78%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

All Most

Q40. How many symptoms would an intranasal corticosteroid have to relieve for you to consider it a successful treatment – all, most, some, a few or none? N=400

PQ101. How many symptoms would a nasal allergy medicine have to relieve for you to consider it a successful treatment --- all, most, some, a few or none? Unweighted N=2,500

160

Percent Symptom Relief for Success

85%

77%

71%73%72%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care NursePrac./Physician

Asst.

Patients

Q41. On a scale of 0 to 100 percent, what percent symptom relief would you expect from an intra-nasal corticosteroid for it to be considered a successful treatment? N=400

PQ102. On a scale of 0 to 100 percent, what percent symptom relief would you expect from a nasal allergy medicine for it to be considered a successful treatment? Unweighted N=2,500

Mea

n

161

How Quick Symptom Relief for Success

54

49

5859

0

10

20

30

40

50

60

70

ENT Allergist Primary care NursePrac./Physician

Asst.

Q42. How quickly after taking would an intra-nasal corticosteroid have to begin relieving symptoms for you to consider it a successful treatment? N=400

Mea

n n

um

ber

of

ho

urs

162

Time Intra-nasals Last for Success

54%

61%

73%

62%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care NursePrac./Physician

Asst.

Q43. How long after taking a dose of intra-nasal corticosteroid should symptom relief last for you to consider it a successful treatment? N=400

Wan

tin

g 2

4-h

ou

rs o

r lo

ng

er (

%)

163

Opinions About Nasal Allergies

Q44. Now I am going to read you a series of statements. As I read each statement, please tell me whether you agree strongly, agree somewhat, disagree somewhat or disagree strongly with the statement. N=400

PQ110. Now I am going to read you a series of statements. As I read each statement , please tell me whether you agree strongly, agree somewhat, disagree somewhat or disagree strongly with the statement. Unweighted N=2,500

82%

71%

25%

49%

78%

77%

35%

30%

1%

38%

70%

55%

44%

24%

1%

45%

73%

58%

55%

28%

15%

22%

56%

64%

79%

58%

2%

40%

59%

3%

0% 20% 40% 60% 80% 100%

Nasal allergies are a serious health problem inthe US

Even with proper treatment nasal allergiesusually cause some lifestyle limitations

There are no truly effective treatments fornasal allergies

Frequent nasal allergy symptoms can beprevented in most cases

Nasal allergies can make asthma worse

Nasal allergies can cause sinus infections

Patients

Nurse Prac./Physician Asst.Primary care

Allergist

ENT

164

Patients Get Monies Worth from Rx Medicines

55%

87%91%

85%82%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Patients

Q30. Overall, do your patients feel they get their money’s worth out of prescription medicines for nasal allergies? N=400PQ97. Overall, do you feel that patients get their money’s worth out of prescription medicines for nasal allergies?

Unweighted N=2,500

Yes

165

Need for Better Education of Patients

49%

38%

37%

43%

40%

57%

52%

61%

57%

43%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Patients

Strong need Moderate need

Q45. How much need do you think there is for better education of PEOPLE WITH NASAL ALLERGIES about their condition and its treatment? Do you think there is a… N=400

PQ113. How much need do you think there is for better education of people with nasal allergies about their condition and its treatment? Unweighted N=2,500

166

Aware of Professional Guidelines

64%

46%

88%

62%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care Nurse Prac./Physician Asst.

Q46a. Are you aware of any professional guidelines for the diagnosis and management of allergic rhinitis? N=400

Yes

167

Publisher of Guidelines

21%

15%

1%

3%

2%

22%

40%

2%

11%

4%

28%

20%

5%

3%

13%

3%

3%

11%

13%

56%

16%

2%

57%

0% 20% 40% 60% 80% 100%

ALA

AMA

ERS

Other medical society

AAOA

Joint task force

AAAAI

ACAAI

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

Q46b. Who publishes those guidelines? Base: Aware of Guidelines N=260

168

Publisher of Guidelines (cont.)

2%

13%

2%

3%

2%

3%

7%

2%

2%

2%

33%

2%

2%

2%

5%

9%

39%

2%

6%

0% 20% 40% 60% 80% 100%

NHLBI

WHO

NIH

AAA

Medical journal

ARIA

Other

Don't know

Nurse Prac./Physician Asst.

Primary care

Allergist

ENT

Q46b. Who publishes those guidelines? Base: Aware of Guidelines N=260

169

Graduation Year

37%

36%

25%

14%

6%

16%

43%3%

21%

42%

27%

28%

29%

35%

22%

15%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

1950 to 1975 1976 to 19851986 to 1995 1996 or later

D1. In what year did you [DOCTOR VER: graduate from Medical or Osteopathic school] [NP/PH VER: receive your license as a physician assistant]? N=400

170

Continuing Medical Education

92%

79%

99%95%

0%

20%

40%

60%

80%

100%

ENT Allergist Primary care NursePrac./Physician

Asst.

D2. Have you taken any continuing medical education (CME) courses related to the management and treatment of allergic rhinitis [DOCTOR VER: since medical school] [PA/NP VER: since receiving your license]? N=400

Yes

171

Primary Practice Location

37%

54%

23%

6%

3%

10%

6%

12%

18%33%

22%

29%

35%

42%

20%

14%

21%

13%

1%

1%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Central city Suburb Small city Town Rural

D3. Is your primary practice located in a central city, a suburb, a small city, a town or a rural area? N=400

172

Gender

14%

24%

79%21%

75%

76%

86%

25%

0% 20% 40% 60% 80% 100%

ENT

Allergist

Primary care

Nurse Prac./PhysicianAsst.

Male Female

D4. Gender N=400