AGROPROCESSING AND NATURALPRODUCTS DIVISION

CSIR-National Institute for Interdisciplinary Science andTechnology (CSIR-NIIST)Thiruvananthapuram,

Microbiologist

Chemists

Biologists

Industry/

The Team ……..

Food Technologists

Chemical Engineers

Flavour Science & Technology (Spices)

Lipid Science & Technology (Oilseeds)

Natural Products (Herbs)- A Chemistry/ Biology/ ChemicalEngineering Interdisciplinary programme

Vision

“ To emerge the first choice of the users of its outputs ofR & D, be it technology, product, service or knowledge”.

Analytical facilities (In-house)

GCMS

HPLC

HPTLC

Confocal Microscope

Flow Cytometer

Real time PCR

Multimode readers

FTIR

Particle size analyser

Texture analycer

Freeze drier/ Lyophiliser

Polarimeter

Colorimeter

Differential canning

colorimeter

Oil seeds/ Flavour Science & Technology Group

7

Services rendered by the Oil seeds/ Spices group

• Process Development

• Technology transfer/ Industrial trouble shooting

• Scale up processes at Pilot Plant

• Preparation of DPR

• Detailed engineering of the plant

• Engineering support for erection and commissioning of the plant

• Training of operating personnel

• ost commissioning assistance and product analysis.

Concept to CommercializationConcept to Commercialization

FRESH GINGER PROCESSING TECHNOLOGY IN NORTH EAST

• NIIST have set up commercial ventures inNorth East states of Manipur, Meghalaya,Sikkim for processing of Ginger, Turmeric andGreen Cardamom

• Technology transfered to Mizoram &Arunachal Pradesh to set up commercial units

• Ensured remunerative return to the ruralfarmers

A New Venture to cater 7.5 TPD ginger is under implementation at Wayanad, Kerala

Current status

Pre Commissioning trials over

TURN KEY EXECUTION FRESH CHILLI PROCESSING UNIT AT BYADAGI

• First venture in India for Processing of 20TPD of Fresh Chillies making High Colour valueadded product free of Aflatoxins

• Continuous processing which can cater chilliright from harvest even during adverseconditions

• Employment for 20 rural unskilled womenand Remunerative prices for farmers

Science & Technology to the rescue of the Chilli farmer

Concept to commercialization

Refrigeration/Adsorption dehumidified drier

Problem Drying during the rainy harvesting

season Very long residence time for drying Development of surface cracks on

dried products Loss of essential oils Oozing out of essential oils on

dried product

Result Operate at lower temperature and

shorter drying time Higher mass transfer rate Improved product quality Catapulted one entrepreneur as

the largest exporter of Nutmegfrom India

SolutionEnergy efficient refrigeration/adsorptiondehumidified drier designed and commissionedCapacity: 2T/day

Processing of Nutmeg prior to 2011: (Counter Clockwise from Top): 1. SunDrying of Nutmeg; 2. Firing of Hot Air Generator 3. Mat over which Nutmegis spread for drying; 4. Drying in Progress

Processing of Nutmeg under New System: (Clockwise from Top): 1. Nutmeg readiedto be loaded into Drier; 2. Nutmeg being stacked in the Insulated Drier Room; 3. TheRADD System

Aflatoxin free products for Exports to New Markets: Europe and USA

Manual sorting to remove un-dried nutmeg; 2. Firing of the Hot Air Generator

Modernized Unit has vastly improved the Quality of Work and Life of Workers

NIISTTBIC

Technical Support

Equipment Lease

Start-up Companies

Fundingagency

Grant for basicinfrastructure

Venture finance

Exit Ventures

“Sweat Equity”

Return on “SweatEquity”

A specialized facility where essential infrastructure, technical expertise and consultancyservices are available

TBIC IN AGRO PROCESSING

A JOINT INITIATIVE OF CSIR – NIIST & GOVT OF KERALA

Entrepreneurs

Natural Products (Auyrveda)

Chemistry/ Biology/ Chemical EngineeringInterdisciplinary programme

EXTRACTSCHEMICAL

ANTIOXIDANTACTIVITY

BIOLOGICAL

ACTIVITY

PRODUCTS:FUNCTIONAL FOODSNUTRACEUTICALS

EVIDENCE BASED HERBAL/NUTARCEUTICAL PRODUCTSFOR PREVENTIVE HEALTH AND DISEASE MANAGEMENT

Products Focus

Herbal pills/soft gel capsules/supplementsBioactive phytochemicals for health management

Health food suppliments: Prevention and managementDiabetes, CVD

Instant drinksMicroencapsulated ready to reconstitutable drinks withantioxidant, immune health and general well being bioactives

Functional vegetable oilWith antioxidant, disease preventive and general well beingbioactives

Functional ShorteningTailor made shortenings with antioxidant, cholesterollowering, health management bioactives

Biology programmes in AP & NP Division

General ObjectivesDevelopment of nutraceuticals for general well being and preventive

healthLead generation from medicinal plants (Ayurveda, traditional

knowledge- documented and non-documented) for diabetes,cancerand cardiovascular disease (CVD)Bioprospection of Western Ghats biodiversity for sustainable useDevelopment of new screening models & biomarker for Diabetes,

CVD & Cancer

Fractionation

Active fractions

Detailed activity studies- antidiabetic,antiinflammatory, anti cancer & against CVD

Antidiabetic studiesAntidiabetic studies

Anti inflammatorystudies

Anti inflammatorystudies

Insulin secretionGlucose uptake

Cell differentiationInflammatory

cytokinesNFkB expression

Insulin secretionGlucose uptake

Cell differentiationInflammatory

cytokinesNFkB expression

Anti oxidant studies-Chemical & cellular

assays

Anti oxidant studies-Chemical & cellular

assays

Active extract

Sequential extraction

Anti oxidant studiesChemical assays

Anti oxidant studiesChemical assays

CVDCVD

Extraction of bioactives and evaluation of biological activity

OXIDATIVESTRESS DIABETES INFLAMMATION CVD CANCER

Free radicals α-amylaseinhibitor COX inhibition In vitro LDL

oxidation MTT

GSH & GSSG α-glucosidaseinhibitor

Interleukinsecretion ACE inhibitor Cell cycle

assay

GPx/GR Glucose uptake NFκB expressionHMGCoAreductaseinhibition

Apoptosis

SODGlut4

expression/translocation

COX expression Angiogenesis

Catalase Adipocytedifferentiation

Models for biological evaluation

Product quality and stability studies

Process development in lab level

Scale up studies in pilot plant

Cost evaluation and feasibility studies

Product supply for test marketing

Product formulation and process development

To sum up ……To sum up ……

Convergence of expertise in Engineering/Food technology/ Biological areasto add value to regional resources

Enzyme assisted processes for active ingredient isolationMarketing of Generic expertise Solvent extraction, drying, oil seeds & spicesprocessing - Engineering new Industrial ventures

Modernization of the traditional Ayurveda sector/ functional , nutraceuticalfood industry

Continue to offer technological support to oil seed / spice industry

Creating the environment and opportunities for new venture creation in Agroprocessing through TBIC by

Market research and preparation of business plans for venture funding ,Technicalco-ordination with statutory agencies, financial institutions and prospective endmarkets Nucleating and accelerating collaborative technology projects suitable for newventure development through TBIC

THANKS