Agilent ICF Support Layer v3 · Support Layer v3.2 installed. Note: Agilent ICF Support Layer v2.2 and later is compatible with Waters Driver Pack 4 and later. GC control considerations

*715006563**Ver.00*

Agilent ICF Support Layer v3.3

Release Notes

715006563Version 00

Copyright © Waters Corporation 2020All rights reserved

General information

Copyright notice© 2020 WATERS CORPORATION. PRINTED IN THE UNITED STATES OF AMERICA AND INIRELAND. ALL RIGHTS RESERVED. THIS DOCUMENT OR PARTS THEREOF MAY NOT BEREPRODUCED IN ANY FORM WITHOUT THE WRITTEN PERMISSION OF THE PUBLISHER.

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Table of contents

General information ....................................................................................................... ii

Copyright notice ..................................................................................................................................... ii

Trademarks ............................................................................................................................................ ii

Agilent ICF Support Layer v3.3 .....................................................................................6

ICF Support Layer architecture..............................................................................................................6

Compliance recommendations ..............................................................................................................7Requalification with Waters' Total Assurance Plans ........................................................................7

New features..........................................................................................................................................8

Driver compatibility.................................................................................................................................8

GC control considerations......................................................................................................................9

System and software requirements ..................................................................................................... 11

Supported modules and firmware ........................................................................................................ 11Agilent LC - Pumps........................................................................................................................12Agilent LC - Sampling Systems.....................................................................................................13Agilent LC - Detectors ...................................................................................................................15Agilent LC - Column Compartments..............................................................................................17Agilent LC - Valve thermostat cluster (VTC)..................................................................................17Agilent LC - Valves, Valve Drives, and Clusters ............................................................................18Agilent LC - Fraction Collectors.....................................................................................................19Agilent LC - Fraction Collector Clusters (FCC)..............................................................................19Agilent LC - Other module types ...................................................................................................20Agilent LC - Systems.....................................................................................................................21Agilent CE - Firmware information.................................................................................................22Supported Agilent gas chromatography hardware ........................................................................22Agilent Gas Chromatograph and Headspace firmware.................................................................25GC Autosampler and Tray Compatibility .......................................................................................26Headspace compatibility................................................................................................................28Agilent GC firmware interoperability and support statements .......................................................28

Importing plate type definitions ............................................................................................................28

Upgrading Agilent ICF Support Layer ..................................................................................................29

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Installation process ..............................................................................................................................29Installing Agilent ICF Support Layer v3.3 ......................................................................................30Installing Agilent ICF Support Layer v3.3 on an Empower Citrix server........................................30Silent and push installations ..........................................................................................................31Silent installations..........................................................................................................................31Push installations...........................................................................................................................33Verifying the installation.................................................................................................................35Uninstalling Agilent ICF Support Layer v3.3..................................................................................36System validation ..........................................................................................................................36

Issues resolved in this release.............................................................................................................36CRI-530 .........................................................................................................................................37CRI-1009 .......................................................................................................................................37CRI-1236 .......................................................................................................................................37CRI-1328 .......................................................................................................................................37CRI-1390 .......................................................................................................................................37CRI-1724 .......................................................................................................................................37CRI-1744 .......................................................................................................................................37CRI-1819 .......................................................................................................................................38CRI-1830 .......................................................................................................................................38

Known issues in this release................................................................................................................38CRI-540 .........................................................................................................................................38CRI-668 .........................................................................................................................................38CRI-672 .........................................................................................................................................39CRI-862 .........................................................................................................................................39CRI-909 .........................................................................................................................................39CRI-1100 .......................................................................................................................................39CRI-1043 .......................................................................................................................................39CRI-1182 .......................................................................................................................................39CRI-1279 .......................................................................................................................................40CRI-1280 .......................................................................................................................................40CRI-1284 .......................................................................................................................................40CRI-1303 .......................................................................................................................................40CRI-1312 .......................................................................................................................................40CRI-1383 .......................................................................................................................................41CRI-1548 .......................................................................................................................................41CRI-1784 .......................................................................................................................................41CRI-1821 .......................................................................................................................................41CRI-1953 .......................................................................................................................................42INFICFSL-716 ...............................................................................................................................42INFICFSL-767 ...............................................................................................................................42INFICFSL-768 ...............................................................................................................................42

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INFICFSL-773 ...............................................................................................................................42INFICFSL-786 ...............................................................................................................................43

Issues addressed in this release..........................................................................................................43CRI-443 .........................................................................................................................................43CRI-742 .........................................................................................................................................43

Agilent PreConfiguration Utility ............................................................................................................43Configuring any type of Agilent GC using the PreConfiguration Utility..........................................44Configuring a GC system to include a headspace sampler...........................................................45Configuring the GC system (with or without a headspace sampler) in Empower..........................47

Options tab in the Instrument Method Editor ......................................................................................48

Dual tower support...............................................................................................................................49Scripts for dual tower support........................................................................................................49Enabling dual tower support in Empower ......................................................................................50

Diagnostics log export..........................................................................................................................52Enabling script for diagnostics log export ......................................................................................52Disabling script for diagnostics log export .....................................................................................52

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Agilent ICF Support Layer v3.3

These release notes explain how to install Waters ICF Support Layer version 3.3 for the AgilentInstrument Control Framework (ICF) version 2.6 Update 3, for control of all supported AgilentLiquid Chromatography (LC) and Gas Chromatography (GC) modules. This software is intendedfor use in conjunction with Empower 3 software in English, Japanese, and Chinese (simplified).

ICF Support Layer architectureThe ICF Support Layer primarily defines an interface for integrating instrument control into anapplication (such as Empower).

Figure 1–1: Interaction between Agilent ICF and Empower

Note: The items in the diagram denote the components of the architectural elements that allowinstruments to interface with Empower. Colors denote these separate layers of control. Itemsmay be housed on separate platforms, such as computers or instruments.

As shown above, Empower interacts with the ICF Support Layer and the ICF Support Layer inturn interacts with Agilent ICF. The ICF Support Layer acts as an interface between Empower and

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Agilent ICF to integrate instrument control into Empower on an instrument level. "Instrumentlevel" means that the ICF aggregates multiple RC.NET drivers to a combined instrument view.Due to the aggregation of multiple drivers, the application adapter layer is more lightweight,because aspects of the functionality and synchronization tasks are already covered within the ICFlayer.

The application and the instrument layers remain the same. But the RC.NET drivers, independentof the host CDS or workstation, can be modeled with finer granularity as required to control themodules.

Note: To understand the full impact of the interaction between the Waters ICF Support Layer andAgilent ICF, you may need more information on Agilent ICF. Refer to the Agilent InstrumentControl Framework (Agilent ICF) document available from the www.agilent.com website.

Important: • You must use the Agilent ICF release notes to understand functionality, including known

issues and supported configurations.

• You must have .NET framework version 4.6.2 (minimum) installed to successfully installAgilent ICF Support Layer.

Compliance recommendationsAny time you install, change, or uninstall software or system modules in a regulated environment,Waters recommends that you follow your organization's approved standard operating procedures.

A risk-based review may assist you in a regulated environment to evaluate changes detailed inthe release notes. Using company SOPs, determine if any documentation updates andrequalification of the system modules, chromatographic system, or chromatographic data system(CDS) are required.

Requalification with Waters' Total Assurance PlansThe Waters' Total Assurance Plan (TAP) with System Qualification Option covers upgrades andrequalification of the instrument driver, software, firmware, or hardware in these cases:

• During yearly requalification, as provided in the plan.

• If installing this release is required for operation of a new module or system, wherequalification of the new module or system is covered by the plan.

Requalification of the CDS software and computers after a driver upgrade may or may not beincluded in your TAP.

Review your TAP to determine which services are covered and which are not covered. Forsituations not covered by the plan, Waters can perform the qualification, but additional chargeswill apply.

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New featuresThis release provides the following new feature:

• Distributes Agilent ICF version 2.6 Update 3 (2.6.33) with LC driver version A.02.19 SR2(2.19.205) and GC driver version 3.1 (3.1.206).

• Agilent ICF Support Layer v3.3 provides support for the CTC Pal Series driver version1.4.0.16.

Note: The CTC driver is not bundled with ICF Support Layer v3.3, it is distributed and ownedby CTC Analytics AG. Contact CTC for more information.

Driver compatibilityThe release of Agilent ICF Support Layer v3.3 provides support for the Agilent ICF modules inICF version 2.6 Update 3 with ICF-LC drivers version A.02.19 SR2 and ICF-GC drivers version3.1.

Drivers are separate from and compatible with previous instrument control using legacy ICSinstrument drivers such as A1100 LC (v1.06), 7890 GC (v2.6), 6850 GC (v1.40), G1888A, andHS7697 headspace samplers (HCO v3.0), and with legacy Empower control for the 6890 GC.Installed legacy instrument control continues to operate with the systems for which it is specified.To allow access to legacy instrument methods, keep the legacy drivers installed on yourEmpower system.

Important: The Agilent ICF Support Layer v3.3 driver is not recommended for 6890 GCsystems configured with a G1888 or a HS7697A, due to known issue CRI-1784. For details, seeKnown issues in this release.

Important compatibility noticesThe Waters ICF Support Layer v3.3 is backward-compatible with LAC/E modules installed withICF Support Layer v3.0, ICF Support Layer v3.1, and ICF Support Layer v3.2 in Empower for thefollowing:

• Agilent Liquid Chromatography (LC)

• Agilent Gas Chromatography (GC) with Liquid Sampler

All LAC/E modules running Agilent GC with Headspace Sampler must be upgraded to ICFSupport Layer v3.1, ICF Support Layer v3.2 with the Agilent ICF A.02.05, or ICF Support Layerv3.3 with the Agilent ICF 2.6 Update 3.

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Figure 1–2: Example of an ICF configuration in a mixed environment

Restriction: You cannot use functionalities included with the ICF Support Layer v3.3 on Agilentsystems connected to a LAC/E with ICF Support Layer v3.0, ICF Support Layer v3.1, or ICFSupport Layer v3.2 installed.

Note: Agilent ICF Support Layer v2.2 and later is compatible with Waters Driver Pack 4 andlater.

GC control considerationsKeep the following in mind when updating to Agilent ICF Support Layer version 3.3.

• Older Agilent drivers (6850 GC, G1888A, HS 7697A, 7890GC) are compatible with AgilentICF version 3.3 drivers. There is no need to uninstall them.

Note: This statement applies only if you are not using the Dual Tower feature. To avoidissues, you must uninstall the 7890 legacy drivers when using the Dual Tower feature.

• You must use Ethernet to connect to the GC instruments. RS232 serial communication is notsupported.

• The vial size is part of the configuration of Agilent G1888A HS and is a method parameter forAgilent 7697A HS. When you change the vial size on Agilent G1888A HS, the GC/HS systemmust be reconfigured using the PreConfiguration Utility.

• Before using the PreConfiguration Utility, it is highly recommended that you check and, ifneeded, adjust the configuration of the GC and HS hardware on the instrument (Gas types,Wash vials, Cool Down mode, Syringe size, Loop volume, Vial size (G1888A), and so on).using the keypad or the touchscreen interface.

• Use a fixed IP address for the GC and HS modules. DHCP is not recommended.

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• In the PreConfiguration utility, change Keypad Lock and Prep Run on Manual Request asneeded. Prep Run on Manual Request should be selected for Agilent G1888A HS andcleared for PAL-XT, PAL3, and Agilent 7697A HS. Prep Run on Manual Request needs notbe selected for manual injections, except when using an Agilent 6850 GC system.

• Do not create a GC instrument method offline. To view GC parameters in the instrumentmethod editor, you must scan and configure the instrument at least one time.

• Provide identical values for instrument method run time and sample set run time.

High and low throughput informationWhen running samples, the following headspace rules apply when you select the highthroughput option:

• The vials must be arranged sequentially (for example, 1, 2, 3).

• All instrument methods must be the same within a sample set.

• The number of injections for each line should be 1.

• Do not select Alter running sample set.

When you select low throughput in the instrument method, you can perform the followingoperations:

• You can arrange the vials in a non-sequential manner.

• Instrument methods can be different within a sample set.

• The number of injections for each line can be more than 1.

• You can select Alter running sample set.

When running samples, the following headspace rules apply:

• Method sets cannot contain instrument methods with both the low and high throughputoptions selected in the same sample set.

• Do not Pause a sample set.

• Do not perform single injections. Use only sample sets.

Agilent 6890, 7890, and 8890/8860 GC injectionsFor Agilent 6890, 7890, and 8890/8860 GCs, injections from the front and back injector towersare configured in this manner:

• Vial numbers 1-150 are injected using the front injector tower.

• Vial numbers 501-650 are injected using the back injector tower.

• Vial numbers 701-703 are injected using the single vial turret of the back injector tower.

Note: No front and back names are used to differentiate between the injectors, as in legacyAgilent 6890 and 7890 GCs. For example, F:1, B:2, and so on are not supported by the ICF-GCdrivers.

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Dual Tower modeIn Dual Tower mode, the vial numbers are specified as alphanumeric values. The vial numbersare used in the following manner:

• Vial numbers F:1-F:150 specify the front injector tower.

• Vial numbers B:1-B:150 specify the back injector tower.

The vial number range varies with turret capacity.

Example: For a 3-vial turret, the numbers should be F:1 to F:3 for the Front injector and B:1 toB:3 for the Back injector.

If the tray is not present, then it works with the turret capacity.

If the GC is configured with a headspace sampler and two Autosampler towers, dual towerfunctionality is not supported with the injector preference.

Note: The 16-vial turret does not support trays.

See also: For dual tower functionality, see Dual tower support.

System and software requirementsWaters supports this Agilent ICF update with Empower 3 Feature Release 2 software (minimum),English, Japanese, and Chinese (Simplified).

Restriction: You cannot install this software on computers with earlier Empower versions orfeature releases.

Agilent ICF Support Layer v3.3 supports the computer configurations, operating systems, andHotfixes that the relevant Empower version supports. For details, refer to the relevant version ofthe Empower 3 Installation, Configuration, and Upgrade Guide and release notes.

For incremental information on the operating system and hotfix support, visit the Waters websitewww.waters.com.

Supported modules and firmwareAgilent ICF Update version 2.6 Update 3, which is installed as part of the Agilent ICF SupportLayer 3.3 product, supports the Agilent LC modules listed in the following tables.

If you follow Agilent guidelines for firmware versions that Waters tested in previous ICF SupportLayer releases, Waters expects no incompatibilities. Consult Agilent or refer to the Agilentwebsite for additional firmware compatibility guidelines.

Recommended firmwareWith the release of Agilent driver version A.02.19 SR2 Waters recommends that you use thefollowing firmware revisions:

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Device Recommended firmware

Agilent 1100 Series, 1200 Series and 1200Infinity

A.07.01 or later

Agilent 1200 Series, 1200 Infinity and 1120Compact LC

B.07.23 or later

Agilent 1200 Infinity Hosted Modules C.07.20 or later

Agilent 1260/1290 Infinity II Modules D.07.23 or later

Note: All modules in that stack require a firmware update within set A/B/C/D.07.01, not only newmodules. For example, the fraction collector uses new detector features.

Agilent LC - Pumps

Product number Module name Minimum required firmwarerevision

G1310A 1200 Series Isocratic Pump A.06.10

G1310B 1260 Infinity Isocratic Pump A.06.32

G1311A 1200 Series QuaternaryPumpa

A.06.10

G1311B 1260 Infinity QuaternaryPumpa

A.06.32

G1311C 1260 Infinity Quaternary PumpVLa

A.06.32

G1312A 1200 Series Binary Pumpa A.06.10

G1312B 1260 Infinity Binary Pumpa A.06.10

G1312C 1260 Infinity Binary Pump VLa A.06.32

G1361A 1260 Infinity Preparative Pumpcluster with up to four

A.06.50

G1376A 1260 Infinity Capillary Pump A.06.10

G2226A 1260 Infinity Nanoflow Pump A.06.10

G4204A 1290 Infinity QuaternaryPumpa

B.06.50

G4220A 1290 Infinity Binary Pumpa B.06.23

G4220B 1290 Infinity Binary Pump VLa B.06.43

G4302A 1260 Infinity SFC BinaryPumpa

A.06.32

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G4782A 1260 Infinity II SFC BinaryPumpa

D.07.13

G5611A 1260 Infinity Bio-InertQuaternary Pumpa

A.06.32

G5654A 1260 Infinity II Bio-InertQuaternary Pumpa

D.07.01

G7104A 1290 Infinity II Flexible Pumpa B.06.71

G7104C 1260 Infinity II Flexible Pumpa D.07.20

G7110B 1260 Infinity II Isocratic Pump D.07.01

G7111A 1260 Infinity II QuaternaryPump VLa

D.07.01

G7111B 1260 Infinity II QuaternaryPumpa

D.07.01

G7112B 1260 Infinity II Binary Pumpa D.07.01

G7120A 1290 Infinity II High-SpeedPumpa

B.06.71

G7161A 1260 Infinity II PreparativeBinary Pump

D.07.20

G7161B 1290 Infinity II PreparativeBinary Pump

D.07.20

a. Pump valve clusters are possible for marked pumps with up to two valves of type G1160A and/or G1170A with 5067-4159 or5067-4147.

Agilent LC - Sampling Systems


G1313A 1100 Series Autosampler A.06.10

G1329A 1200 Series StandardAutosampler

A.06.10

G1329B 1260 Infinity StandardAutosampler

A.06.10

G1367A 1100 Series Well-PlateAutosampler

A.06.31

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G1367B 1200 Series High-PerformanceAutosampler

A.06.31

G1367C 1200 Series High-PerformanceAutosampler SL

A.06.31

G1367D 1200 Series High-PerformanceAutosampler SL+

A.06.31

G1367E 1260 Infinity High-Performance Autosampler

A.06.32

G1377A 1260 Infinity High-Performance MicroAutosampler

A.06.12

G1389A 1100 Series MicroThermostatted Autosampler

A.06.10

G2258A 1260 Infinity Dual-LoopAutosampler

A.06.50

G2260A 1260 Infinity PreparativeAutosampler (high flow)

A.06.50

G4226A 1290 Infinity Autosampler A.06.31

G4303A 1260 Infinity SFC StandardAutosampler

A.06.54

G4767A 1260 Infinity II SFCMultisampler

D.07.13

G5667A 1260 Infinity Bio-Inert High-Performance Autosampler

A.06.32

G5668A 1260 Infinity II Bio-InertMultisampler

D.07.13

G7167A 1260 Infinity II Multisampler D.07.13

G7167B 1290 Infinity II Multisampler D.07.13

G7129A 1260 Infinity II Vialsampler D.06.76

G7129B 1290 Infinity II Vialsampler D.06.76

G7129C 1260 Infinity II Vialsampler D.07.20

G7157A 1260 Infinity II PreparativeAutosampler

D.07.01

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Agilent LC - Detectors


G1314A 1100 Series VariableWavelength Detector

A.06.10

G1314B 1260 Infinity VariableWavelength Detector VL

A.06.10

G1314C 1260 Infinity VariableWavelength Detector VL+

A.06.10

G1314D 1200 Series VariableWavelength Detector

B.06.32

G1314E 1290 Infinity VariableWavelength Detector

B.06.32

G1314F 1260 Infinity VariableWavelength Detector

B.06.32

G1315A 1100 Series Diode ArrayDetector

A.06.10

G1315B 1200 Series Diode ArrayDetector

A.06.10

G1315C 1260 Infinity Diode ArrayDetector VL+

B.06.30

G1315D 1260 Infinity Diode ArrayDetector VL

B.06.30

G1365A 1100 Series MultipleWavelength Detector

A.06.10

G1365B 1200 Series MultipleWavelength Detector

A.06.10

G1365C 1260 Infinity MultipleWavelength Detector

B.06.30

G1365D 1260 Infinity MultipleWavelength Detector VL

B.06.30

G1321A 1200 Series FluorescenceDetector (FLD)

A.06.10

G1321B 1260 Infinity FluorescenceDetector Spectra

A.06.32

G1321C 1260 Infinity FluorescenceDetector

A.06.54

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G1362A 1260 Infinity Refractive IndexDetector

A.06.10

G4212A 1290 Infinity Diode ArrayDetector

B.06.30

G4212B 1260 Infinity Diode ArrayDetector

B.06.30

G4212A/B HDR-DAD Cluster 2x G4212A or 2x G4212B or acombination of 1x G4212A and1x G4212B

B.06.57

G4260B 1260 Infinity II ELSD a 32.06

G7102A 1290 Infinity II ELSD (LANonly)a

32.06

G7114A 1260 Infinity II VariableWavelength Detector

D.07.01

G7114B 1290 Infinity II VariableWavelength Detector

D.06.70

G7115A 1260 Infinity II Diode ArrayDetector WR

D.07.01

G7117A 1290 Infinity II Diode ArrayDetector FS

D.06.70

G7117B 1290 Infinity II Diode ArrayDetector

D.06.70

G7117C 1260 Infinity II Diode ArrayDetector HS

D.07.01

G7117A/B HDR-DAD Cluster 2x G7117A or 2x G7117B or acombination of 1x G7117A and1x G7117B

D.06.70

G7121A 1260 Infinity II FluorescenceDetector

D.07.01

G7121B 1260 Infinity II FluorescenceDetector Spectra

D.07.01

G7165A 1260 Infinity II MultipleWavelength Detector

D.07.01

G7162A 1260 Infinity II Refractive IndexDetector

D.06.76

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G7162B 1290 Infinity II Refractive IndexDetector

D.06.76

a. Per Agilent ELSD drivers revision A.01.07 Release Notes, it is not possible to use the existing instrument methods created byprevious versions of the ELSD driver. Loading an instrument method created using a previous version of the ELSD driverresults in " Error 102 method mismatch." New methods must be created.

Agilent LC - Column Compartments


G1316A 1260 Infinity ThermostattedColumn Compartment

A.06.10

G1316B 1200 Series ColumnCompartment SL

A.06.10

G1316C 1200 Series ThermostattedColumn Compartment SL a

A.06.14

G7116A 1260 Infinity II MulticolumnThermostat[firmware for host module inbrackets]

C.07.01 [B.07.01/D.07.01]

G7116B 1290 Infinity II MulticolumnThermostat[firmware for host module inbrackets]

C.06.75 [B.06.75/D.06.75]

G7130A Integrated ColumnCompartment ICC

D.06.76

a. Cluster with up to three G1316Cs with integrated 8pos/9port valves (products G4230A/B). Minimum two G1316C TCCs; thethird TCC can be a G1316A, B, or C.

Agilent LC - Valve thermostat cluster (VTC)The valve thermostat cluster (VTC) is a combination of G7116B, G1170A, and G1316C, as valveor column hosts, and G1316A/B and G7130A, as column hosts.

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Table 1–1: Supported Valve Thermostat Cluster (VTC) firmware

Module Minimum module firmware Minimum host modulefirmware

G7116B C.06.75 B.06.75/D.06.75

G1170A C.06.75 B.06.75/D.06.75

G7130A (within G7129A/B) D.06.76 N/A

G1316C A.06.55 N/A

G1316A/B A.06.10 N/A

Agilent LC - Valves, Valve Drives, and Clusters


G1156A 1200 Series 6 Position / 7 PortValve (400 bar)

A.06.02

G1157A 1200 Series 2 Position / 10Port Valve

A.06.02

G1158A 1200 Series 2 Position / 6 PortValve

A.06.02

G1158B 1200 Series 2 Position / 6 PortValve (600 bar)

A.06.02

G1159A 1200 Series 6 PositionSelection Valve

A.06.02

G1160A 1100 Series Multiple PurposeSwitching Valve (12 Position /13 Port)

A.06.02

G1162A 1200 Series 2 Position / 6 PortMicro Valve

A.06.02

G1163A 1200 Series 2 Position / 10Port Micro Valve

A.06.02

G1170A 1290 Infinity Valve Drive[firmware for host module inbrackets]

C.06.40[B.06.40/D.06.60]

G9322A 1260 Infinity II Clustering Valve(firmware for the host module)

D.07.23

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Agilent LC - Fraction Collectors


G1364A 1100 Series AutomaticFraction Collector Cluster ofup to 3 a

A.06.53

G1364B 1260 Infinity Fraction Collector(preparative-scale) Cluster ofup to 3 a

A.06.53

G1364C 1260 Infinity Fraction Collector(analytical-scale) Cluster of upto 3 a

A.06.53

G1364D 1100 Series Micro FractionCollector

A.06.53

G1364E 1260 Infinity II PreparativeFraction Collector b

D.07.23

G1364F 1260 Infinity II AnalyticalFraction Collector b

D.07.23

G5664A 1260 Infinity Bio-inert FractionCollector AS

A.06.53

G5664B 1260 Infinity II Bio-inertFraction Collector b

D.07.23

G7159B 1290 Infinity II PreparativeOpen-Bed Fraction Collector c

D.07.23

G7166A 1260 Infinity II PreparativeValve-Based Collector[firmware for host module inbrackets]

C.07.20 [B.07.23/D.07.23]

a. Any combination of G1364A/B/C or G5664A plus a fourth G1364A/B/C or G5664A for recovery can be clustered. Multipleindividual Fraction Collectors are not supported.

b. Can be clustered with a G7166A or the same module type for recovery collection.

c. Can be clustered with a G7166A for Recovery.

Agilent LC - Fraction Collector Clusters (FCC)The Fraction Collector Cluster is a combination of multiple preparative or analytical fractioncollectors.

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Preparative Fraction Collectors (G1364E, G7159B, G7166A) can be clustered with a G9322AClustering Valve. Analytical Fraction Collectors (G1364F, G5664B) can be clustered with a QuickChange Valve (G1170A with 5067-4159 or 5067-4194).

Possible Fraction Collector (FC) Possible RC

1x G1364E 1x G7166A or G1364E

1x G1364F 1x G7166A or G1364F

1x G5664B 1x G7166A or G5664B

1x G7159B 1x G7166A

up to 3x G1364E up to 1x G7166A or G1364E

up to 3x G1364F up to 1x G7166A or G1364F

up to 3x G5664B up to 1x G7166A or G5664B

up to 3x G7159B up to 1x G7166A

up to 3x G7166A -

Agilent LC - Other module types

Product Number Module name Minimum required firmwarerevision

G1390A a 1100 Series UniversalInterface Box (UIB)

A.06.02

G1390B a 1200 Infinity Series UniversalInterface Box II [firmware forhost module in brackets]

C.06.53[B.06.53/D.06.60]

G4227A 1290 Infinity Flexible Cube[firmware for host module inbrackets]

C.06.52[B.06.52/D.06.60]

G4240A Chip Cube A.06.36

G4301A 1260 Infinity Analytical SFCSystem

A.03.09

G7170B 1290 Infinity II MS FlowModulator[firmware for host module inbrackets]

C.07.20 [B.07.20/D.07.20]

a. The UIB is not compatible with CE modules.

April 29, 2020, 715006563 Ver. 00Page 20

Agilent LC - Systems


G4286A 1120 Compact LC, Isocratic B.06.50

G4286B 1220 Infinity LC SystemIsocratic, Man. Inj., VWD, 600bar

B.06.50

G4287A 1120 Compact LC, Isocraticwith Oven and ALS

B.06.50

G4287B 1220 Infinity LC Isocratic, ALS,TCC, VWD, 600 bar

B.06.50

G4288A 1120 Compact LC, Gradient B.06.50

G4288B 1220 Infinity LC Gradient,Man. Inj., VWD, 600 bar

B.06.50

G4289A 1120 Compact LC, Gradientwith Oven

B.06.50

G4289B 1220 Infinity LC Gradient,ALS, TCC, VWD, 600 bar

B.06.50

G4290A 1120 Compact LC, Gradientwith Oven and ALS

B.06.50

G4290B 1220 Infinity LC Gradient,ALS, Man. Inj., TCC, VWD,600 bar

B.06.50

G4291B 1220 Infinity LC Isocratic, Man.Inj., TCC, VWD, 600 bar

B.06.50

G4292B 1220 Infinity LC Isocratic, ALS,VWD, 600 bar

B.06.50

G4293B 1220 Infinity LC Gradient,ALS, VWD, 600 bar

B.06.50

G4294B 1220 Infinity LC Gradient,ALS, TCC, DAD, 600 bar

B.06.50

G4288C 1220 Infinity LC System VL,Gradient, Man. Inj. VWD, 400bar

B.06.50

G4289C 1220 Infinity LC System VL,Gradient, Man. Inj. VWD, 400bar

B.06.50

April 29, 2020, 715006563 Ver. 00Page 21


G4290C 1220 Infinity LC System VL,Gradient, ALS, TCC, VWD,400 bar

B.06.50

G4293C 1220 Infinity LC System VL,Gradient, ALS, VWD, 400 bar

B.06.50

Agilent CE - Firmware information


G7150A G7100 CapillaryElectrophoresis II

B.06.25

G7151A Diode Array Detector for CE B.06.25

Supported Agilent gas chromatography hardware

Agilent GC modelnumber

Module name Inlets (describedbelow)

Detectors (describedbelow)

8890 G3540A S/S, P/P, COC, PTV,PCM, VI, MMI, HT‐PTV

TCD, FID, NPD, FPDECD, μECD, Dual WFPD, AIB

G3542A S/S, P/P, COC, PTV,PCM, VI, MMI, HT‐PTV






8860 G2790A S/S, P/P, COC, PCI TCD, FID, NPD,μECD, FPD, FPD+

April 29, 2020, 715006563 Ver. 00Page 22




Intuvo 9000 G3950A S/S, MMI TCD, FID, NPD, FPDECD, μECD, XCD

G3952A S/S, MMI TCD, FID, NPD, FPDECD, μECD, XCD

G3953A S/S, MMI TCD, FID, NPD, FPDECD, μECD, XCD

7890B and 7890A+ G3440B S/S, P/P, COC, PTV,PCM, VI, MMI, HT-PTV

TCD, FID, NPD, FPDECD, μECD, Dual WFPD, AIB, XCD

G3442B S/S, P/P, COC, PTV,PCM, VI, MMI, HT-PTV






7890A G3440A S/S, P/P, COC, PTV,PCM, VI, MMI, HT-PTV


G3442A S/S, P/P, COC, PTV,PCM, VI, MMI, HT-PTV






7820 G4350A S/S, P/P, COC, PCIa TCD, FID, NPD,μECD, FPD, FPD+

6890A G1530A S/S, P/P, COC, PTV,PCM, VI


G1540A S/S, P/P, COC, PTV,PCM, VI


April 29, 2020, 715006563 Ver. 00Page 23




6890Plus G1530A S/S, P/P, COC, PTV,PCM, VI


G1540A S/S, P/P, COC, PTV,PCM, VI


6890N G1530N S/S, P/P, COC, PTV,PCM, VI


G1540N S/S, P/P, COC, PTV,PCM, VI


6850 G2630A/B S/S, P/P, COC, PTV TCD, FID, NPD, ECD,FPD, AIB

a. For PCI, GC revision A.01.18 or higher and GC driver version B.01.01 or higher.

Table 1–2: Inlet descriptions

Inlet abbreviation Description

S/S Split/Splitless

P/P Purged/Packed

COC Cool On-Column

PTV Programmable Temperature Vaporization

PCM Pneumatics Control Module

VI Volatiles Interface

MMI Multimode Inlet

HT-PTV High Temp-PTV

PCI Packed Column EPR Inlet

Table 1–3: Detector descriptions

Detector abbreviation Description

TCD Thermal Conductivity Detector

FID Flame Ionization Detector

NPD Nitrogen Phosphorus Detector

FPD Flame Photometric Detector

April 29, 2020, 715006563 Ver. 00Page 24

Table 1–3: Detector descriptions (continued)

Detector abbreviation Description

μECD micro Electron Capture Detector

Dual W FPD Dual Wavelength Flame Photometric Detector

AIB Analog Input Board

XCD (Sulphur or Nitrogen) ChemiluminescenceDetector

ECD Electron Capture Detector

Agilent Gas Chromatograph and Headspace firmware

Product number Communication type Minimum firmware

Agilent 6890 Series I and IIGas Chromatographs

Ethernet A.03.08

Agilent 6890A and 6890+ GasChromatographs

Ethernet A.03.08

Agilent 6890N GasChromatograph

Ethernet N.06.07

Agilent 6850 Series GasChromatograph(serial numbers <10243001)

Ethernet A.03.07

Agilent 6850 Series II NetworkGas Chromatograph(serial numbers >10243001)

Ethernet A.06.02

Agilent 7820A GasChromatograph

Ethernet A.01.17.004

Agilent 7890A GasChromatograph

Ethernet A.01.16

Agilent 7890B GasChromatograph

Ethernet B.02.04

Agilent Intuvo 9000 GasChromatograph

Ethernet A.01.03

Agilent G1888A HeadspaceAutosampler

Ethernet A.01.10

Agilent HS7697A HeadspaceSampler (G4556A, G4557A)

Ethernet A.01.08

April 29, 2020, 715006563 Ver. 00Page 25

Product number Communication type Minimum firmware

Agilent 8890 GasChromatograph

Ethernet 2.0

Agilent 8860 GasChromatograph

Ethernet 2.0

GC Autosampler and Tray CompatibilityNotes: • Communication for GC samplers and trays is handled through the GC.

• All trays must be in the 7793 range of devices. Trays older than the 7793 range are notsupported.

Agilent GC model number Module name Module type

Intuvo 9000 series 7693A G4513A Injector

G4514A Tray

G4515A BCR/Mixer

G4521A LVI Syringe Carriage

G4522A Cooling Accessory

G4520A Tray with BCR/Mixer

7650 G3430A GC ALS Controller

G4567A Injector

7890 Series 7693A G3430A GC ALS Controller

G4513A Injector

G4514A Tray

G4515A BCR/Mixer




7683A G2613A Injector

G2614A Tray

G2615A BCR/Mixer

7683B G2913A Injector

G2614A Tray

April 29, 2020, 715006563 Ver. 00Page 26


G2615A BCR/Mixer


G4567A Injector

7820 Series 7693 G3430A GC ALS Controller

G4513A Injector


G4567A Injector

6890 7693 G4516A ALS Controller

G4513A Injector

G4514A Tray

G4515A BCR/Mixer

G4517A 6890 Plus ALS Card




7683B G2912A ALS Controller

G4516A ALS Controller

G2913A Injector

G2614A Tray

G2916A Tray

G2615A BCR/Mixer

7683A G2612A ALS Controller

G4516A ALS Controller

G2613A Injector

G2614A Tray

G2615A BCR/Mixer

7673C G1512A ALS Controller

G1513A Injector

18596C Tray

G1926A BCR/Mixer

7673B 18593B Injector

18596B Tray

G2615A BCR/Mixer

April 29, 2020, 715006563 Ver. 00Page 27


6850 7683B G2613A Injector

7693 G4513A Injector

6850 G2880A Injector

Headspace compatibilityCommunication is handled via the LAN.

Agilent GC model number Module type

7697A G4556A

7697A G4557A

G1888A Headspace

Agilent GC firmware interoperability and support statementsAgilent releases GC firmware updates independently of software releases.

All Agilent GC instrument firmware revisions are designed to be backward-compatible with theinstalled instrument base.

Agilent recommends using the latest module firmware revision to provide the highest level ofsystem capability.

Importing plate type definitionsYou can import or select plate type definitions using the Configuration Manager window.

To import plate type definitions:

1. Select Configuration Manager > Plate Types.

2. Inside a row in the Plate Type Name field, right-click, and select Import from Text.

Alternative: Right-click in the field, and select New to specify a new plate type name,and then click OK.

3. Type the path and name of the plate type file, or browse to the location of the file.

4. Type a name for the new plate type definition, and then click OK.

April 29, 2020, 715006563 Ver. 00Page 28

Upgrading Agilent ICF Support Layer

To upgrade Agilent ICF Support Layer:

1. Log in to the computer as a user with local Administrator privileges.

2. Ensure that Empower 3 software and version 3.0, 3.1, or 3.2 of the Agilent ICF SupportLayer are installed on the computer.

3. Restart the computer.

4. Browse to the location of the upgrade build, and then double-click the Setup.exe file.

5. Follow all prompts to complete the upgrade.

6. To complete the installation, restart the computer.

Requirement: Using Windows' Computer Management, verify that the Waters DHCPServer service is running before you power-on the Agilent instruments.

7. Power-on the Agilent instruments.

Installation processTo use this software on an Empower Enterprise (client/server) system, you must install it on everyLAC/E module, client, and Citrix application server that interacts with the Agilent instrument, itsmethods, or results. You should not install the Waters ICF Support Layer v3.3 software on thedatabase server unless the server hosts Empower client software and interacts with the Agilentinstrument, its methods, or data.

Note: For compatibility information, see Driver compatibility section.

Before installationBefore you install Waters ICF Support Layer v3.3 software, you must remove the followingsoftware, if present, using Microsoft's Add/Remove Programs feature:

• Agilent ICF Support version 2.2.1 in support of the CTC Analytics PAL 3 robotic sampler

• Agilent ICF Support version 1.0 drivers, including:

• Agilent LC (version 1.0.0.0)

• Agilent ICF (version 1.02.24)

• Agilent ICF - LC Drivers (version 1.02.017)

Recommendation: Back up all Empower software projects, library information, and databasesbefore beginning the installation process.

April 29, 2020, 715006563 Ver. 00Page 29

Installing Agilent ICF Support Layer v3.3Note: These instructions are not applicable for installing the ICF Support Layer v3.3 on anEmpower Citrix application server. See the separate topic Installing Agilent ICF Support Layerv3.3 on an Empower Citrix server.

To install the Agilent ICF Support Layer v3.3 using a downloaded executable file:

1. Power-off the Agilent instruments and restart the computer.

2. Log in to the computer using an account with local administrator privileges.

3. Download the ICF_Support_v33.exe file.

4. Double-click the ICF_Support_v33.exe file to extract the installation files to a temporarylocation.

5. Browse to the temporary location, open the ICF Support v33 folder, and then double-clickthe Setup.exe file.

6. Follow all prompts to complete the installation.

7. To complete the installation, restart the computer.

Requirement: Using Windows' Computer Management, verify that the Waters DHCPServer service is running before you power-on the Agilent instruments.

8. Power-on the Agilent instruments.

Installing Agilent ICF Support Layer v3.3 on an Empower Citrix server

To install Agilent ICF Support Layer v3.3 on an Empower Citrix server:

1. Download the ICF_Support_v33.exe file.

2. Browse to the ICF_Support_v33.exe file and double-click it to extract the installationfiles to a temporary location.

3. Put the server in Install mode by opening a command prompt and typing Change user/install.

Result: A message appears: User session is ready to installapplications.

4. Browse to the ICF Support v33 folder.

5. Select the Setup.exe file, and then click Open.

Tip: To see the file, you may need to select All Files from the Files of type list.

6. Follow all prompts to complete the installation.

7. Return the server to Execute mode by opening a command prompt and typing Changeuser/execute.

April 29, 2020, 715006563 Ver. 00Page 30

Silent and push installationsYou can install or remove the Agilent ICF Support Layer v3.3 software using either a silent or apush installation. Both silent and push installations and removals are unattended, meaning thatthese operations do not require user interaction.

During a silent installation or removal, you deploy Agilent ICF Support Layer v3.3 on a singleEmpower client, LAC/E module, or Citrix server. You store the information required for theoperation in a response file and an instrument-driver list file. You then call both files from acommand prompt or from the commands in a batch file.

During a push installation or removal, you deploy Agilent ICF Support Layer v3.3 to multipleEmpower clients, LAC/E modules, or Citrix servers from a host computer. You control pushinstallations and removals using PsExec, a Microsoft command-line tool. When you run PsExec,the response file is called as a command line argument after the setup.exe file.

Silent installations

Create or modify the response fileCreate or update the response file. The response file must be in XML format, using the correctXML syntax. You can update the response file, but the file extension must remain .RSP. The fileyou need to modify is located in the \\ICF Support v33\Push Install\ICS_Response_EN.rsp folder. If you create a new response file, save it and name it ICS_Response_EN.rsp, and then replace the original file in the aforementioned location.

ICS_Response_EN.rsp

<?xml version="1.0" encoding="utf-8" ?> <Configuration>  <ACTION>InstallAll</ACTION>

  <LANGUAGE></LANGUAGE>

 <ICS_LIST>\\share\ICF Support v33\Push Install\ICS_List_EN.txt</ICS_LIST>

 <LOG_FILE_NETWORK_LOCATION>\\share\Logs</LOG_FILE_NETWORK_LOCATION>-->

April 29, 2020, 715006563 Ver. 00Page 31

 <RESTART>false</RESTART>

 <WORKING_DIRECTORY>\\share</WORKING_DIRECTORY> </Configuration>

Note: Share is the name of the share folder created with the installation media Agilent ICFSupport Layer v3.3.

Performing a silent installation or removal

To perform a silent installation or removal:

1. For silent installations on a LAC/E module, skip step 1 and proceed to step 2. If you areinstalling or removing the Agilent ICF Support Layer v3.3 software on a Citrix server, putthe Citrix server in Install mode by opening a command prompt and typing Changeuser /install.

2. In the response file, do one of the following:

• To install drivers, ensure that the ACTION property is set to InstallALL.

• To remove drivers, ensure that the ACTION property in the response file is set to RemoveAll.

See also: Create or modify the response file

3. Place the Build inside the created Share folder.

4. In the ICS_Response_EN.rsp file, update the IP of the destination machine where youplan to install the Agilent ICF Support Layer v3.3 build.

5. Run Setup.exe from a command prompt or from a batch file.

Requirement: The command must include the name of the response file and the path to Setup.exe; for example, \\Share\ICF Support v33\Setup.exe /responseFile\ICF support v33\Push Install\ICS_Response_EN.rsp.

Result: The Agilent ICF Support Layer v3.3 instrument drivers are installed on orremoved from the LAC/E module or Citrix server. Ensure that the node restarts.

6. If you are installing or removing the Agilent ICF Support Layer v3.3 software on a Citrixserver, return to Execute mode by opening a command prompt and typing Change user/execute.

Note: Removing the ICF Support Layer v3.3 software does not remove the Agilent ICF orICF Drivers. See Uninstalling Agilent ICF Support Layer v3.3.

April 29, 2020, 715006563 Ver. 00Page 32

Push installations

Push installation requirementsAgilent ICF Support Layer v3.3 software supports push installations for instrument componentsoftware using a Microsoft tool called PsExec. This utility is not included in the media, but you candownload it using the following link: http://technet.microsoft.com/.

At this site, type psexec in the search box and click Search. Click the PsExec link and follow theinstructions for downloading and installing the latest version of PsExec.

Using PsExec involves the following tasks:

• Creating or updating the response file.

• Placing the Agilent ICF Support Layer v3.3 software in the shared path.

• Obtaining local administrator privilege on each Citrix server or LAC/E module.

• Running the PsExec command in DOS, specifying the destination system where the AgilentICF Support Layer v3.3 software is to be installed, along with the network path of the setupfile placed in the server.

Restriction: When you perform a push installation on multiple computers, you must use thesame type of computer for each installation (for example, all Citrix servers or all LAC/E modules).You cannot push installations onto a mix of computer types.

Enabling administrative shares on Windows 10

When you perform a push installation on Windows 10, you might need to enable theadministrative shares by adding a new registry entry. If the administrative shares are not enabled,a push installation results in an Access denied error message.

To enable administrative shares on Windows 10:

1. Open Registry Editor by typing regedit in the search box on the taskbar.

2. Navigate to HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\policies\system.

3. Right-click System and select New > DWORD (32-bit).

4. Type the name LocalAccountTokenFilterPolicy and press Enter.

5. Right-click LocalAccountTokenFilterPolicy, and then click Modify.

6. In the Value box, type 1, and then click OK.

7. Exit Registry Editor.


April 29, 2020, 715006563 Ver. 00Page 33

http://technet.microsoft.com/

Performing a push installation or removal

To perform a push installation or removal:

1. For push installation/removal of the Agilent ICF Support Layer v3.3 software on an LAC/Emodule, put the Citrix server in Install mode by opening a command prompt and typing Change user / install.

2. In the response file, do one of the following:

• To install drivers, ensure that the ACTION property is set to InstallALL.

• To remove drivers, ensure that the ACTION property in the response file is set to RemoveAll.

See also: • Create or modify the response file

• Create the node list file.

3. Place the Build inside a shared folder.

4. In the ICS_Response_EN.rsp file, verify the IP/hostname of the shared path.

5. For push installations on a LAC/E module, run Setup.exe from a command prompt orfrom a batch file.

Requirement: The command must include the name of the response file and the path to Setup.exe. For example, psexec@Share\ICF support v33\Push Install\nodes.txt \\Share\\ICF Support v33\Setup.exe /responseFile \\ Share\ICF support v33\Push Install\ICS_Response_EN.rsp \i \sResult: The Agilent ICF Support Layer v3.3 instrument drivers are installed on orremoved from the LAC/E modules. Ensure that the computer restarts.

Note: Removing the ICF Support Layer v3.3 software does not remove the Agilent ICF orICF drivers. See Uninstalling Agilent ICF Support Layer v3.3.

Important: Ensure that your antivirus program allows psExec to run and perform thepush installation.

Create the node list file

To create the node list file:

1. Create a .txt file on the computer on which you will perform the installation or removal.

2. List in the .txt file the names or IP addresses of all the Empower clients, LAC/E modules,or Citrix servers on which to install instrument drivers or from which to remove them.

Note: Use a separate line for each item.

April 29, 2020, 715006563 Ver. 00Page 34

Verifying the installation

To verify the installation:

1. Click Start > All Programs > Empower > Empower Installation Log.

2. Search for lines similar to these:

************************************************************** DM [09:41:25:776 AM]: Product: ICF Support -- Installation completed successfully.DM [09:41:42:601 AM]: Completed the installation of Agilent Instrument Control FrameworkDM [09:42:30:620 AM]: Completed the installation of Agilent Instrument Control Framework - Driver PackageDM [09:42:55:045 AM]: Completed the installation of Agilent Instrument Control Framework - Driver Package

**************************************************************3. Click Start > All Programs > Empower > Verify Files to run the Verify Files utility and

generate a checksum.txt file.

Tip: The checksum.txt file documents the installation of options or service packs andverifies the integrity of disk files by comparing their current CRCs and sizes with theoriginal values recorded during installation of the base software and any installed option orservice pack.

Result: Once executed, reports are generated in a browser window. The reports are alsosaved in the user's Temp folder and in the Empower\Script folder.

Note: Files installed for the Agilent ICF support are not included in the checksum.txtfile generated by the Verify Files utility. To verify the installation for the Agilent ICFcomponents, execute the following batch file: \Empower\Instruments\AgilentLC\IQTWizard\ICFIQT.bat. If the computer name is longer than 15 characters, the IQT.exe does not run properly and does not provide feedback or generate reports. Agilentdocumented this issue as 278675.

4. From the Windows Control Panel of the LAC/E module, Citrix server, or Client, access Programs and Features and confirm that the following versions are installed:

Figure 1–3: Installed Agilent ICF Support and ICF Drivers from Windows ControlPanel

April 29, 2020, 715006563 Ver. 00Page 35

Uninstalling Agilent ICF Support Layer v3.3To ensure that file verification is successful following the removal of the software, you must restartthe computer before you uninstall the Agilent ICF Support.

Note: Remove Agilent ICF Support Layer v3.3 before you uninstall ICF-LC or ICF-GC instrumentdrivers.

To uninstall Agilent ICF Support Layer v3.3:


2. Select Start > All Programs > Empower > Remove Waters Instrument ComponentSoftware.

3. Click Remove.

4. Select the product you want to remove, and then click Next.

5. Follow the prompts to remove the instrument component software from your system.

Result: The registry and new CRC checksums are updated for the Empower softwareinstallation. Oracle software or system files are not affected.

Note: Removing Waters Agilent ICF Support Layer v3.3 does not remove the Agilent ICFsoftware itself. You can remove the Agilent ICF software through the Microsoft Windows Programs and Features utility. To remove Agilent ICF from Programs and Features,select and remove Agilent Instrument Control Framework 2.6 Update 3 first, and thenremove the other two drivers (GC/HS Drivers 3.1 and LC Drivers A.02.19 SR2).


System validationAfter you install or uninstall the software on a qualified system, determine if the system requiresre-qualification according to your laboratory's standard operating procedures.

Requirement: If this is the initial installation in a GxP-regulated environment, perform a fullqualification of the Empower software.

Recommendation: Run the Verify Files utility or the SystemsQT for Empower IQ, and thenreview the resulting file for an entry that states No installation changes were detected.

Tip: The date displayed when running Verify Files (or Empower IQ) reflects only the most recentinstallation. See the Empower.log file for the complete history.

Issues resolved in this releaseThis section lists the problems resolved in this release. The numbers identify issues that Waterspersonnel monitor within a system change request tracking tool.

April 29, 2020, 715006563 Ver. 00Page 36

CRI-530Previously, in versions 3.1 and 3.2 of the Agilent ICF Support Layer, part of the Agilent plateswere missing from the AgilentPlatesForImport folder and could not be imported.

Now, all Agilent plates are available for import.

CRI-1009The Invalid injection volume error no longer occurs when operating with two runningGCs with ALS + HS.

CRI-1236The ICF Support Layer v3.3 installation wizard supports Chinese and Japanese localization.

Note: The issue was particular to ICF v3.2.

CRI-1328Previously, when a 6890 GC and a 7890 GC were configured on the same LAC/E, the Agilentplug-in stopped functioning.

Now, in the same scenario, the Agilent plug-in functions as expected.

CRI-1390Previously, with an Agilent LC system, the Condition column function resulted in an InstrumentFailure Bad Data error.

Now, the Condition column function completes successfully.

CRI-1724Previously, in version 3.2 of the Agilent ICF Support Layer, the Enable Analysis sample coolerfunction was not available in instrument methods.

Now, the function is available.

CRI-1744In version 3.2 of the Agilent ICF Support Layer, the Vial Plate definition did not specify the correctdimensions, as defined in version 3.0 of the Agilent ICF Support Layer.

April 29, 2020, 715006563 Ver. 00Page 37

Now, the Vial Plate definition is correct.

CRI-1819Previously, with Agilent ICF Support Layer v3.2 and Agilent ICF v2.6 drivers, the 1290 ELSD7102A detector remained stuck in the pre-run state for 600 seconds, and then generated the Server busy error.

Now, the issue no longer occurs.

CRI-1830Previously, when running a sample set on an Agilent GC with an Agilent Headspace Sampler inlow throughput mode, the Alter running sample function did not work as expected. The systemdisplayed the Waiting for injection message in the Run Samples window and did notproceed to the next injection.

Now, in the same scenario, the Alter running sample function works as expected.

Known issues in this releaseThis section lists the known issues and solutions for this release. The numbers identify issuesthat Waters and Agilent personnel monitor within a system change request tracking tool.

For the Agilent ICF 2.6 Update 3 there are no known issues; however, refer to Agilentdocumentation for their reported issues.

CRI-540After changing the vial size in ICF pre-configuration for G1888 Headspace, the Vial Missingerror message appears in the Message Center. The issue occurs with Agilent drivers.

Solution: Click Quit in the error message window, reopen Agilent pre-configuration utility, andverify that the configuration matches the G1888 settings.

Note: Agilent documented the issue as defect number 292088.

CRI-668On a 7890B GC, Monitor Baseline stops when reaching the method run time and fails to functionas expected. The issue occurs with Agilent drivers.

Note: Agilent documented the issue as defect number 291784.

April 29, 2020, 715006563 Ver. 00Page 38

CRI-672Installing the ICF 3.0/3.1 build writes the 1019 Missing ICF Support configuration inthe ACQUITY components list error in the installation file.

Solution: The error can be safely ignored. The Agilent ICF installs correctly despite the log fileentry.

CRI-862Performing a silent installation of the Agilent Instrument Control Framework (ICF) writes the 3010error code to the installation log file.

Solution: The error requests a restart and you can safely ignore it. The Agilent ICF installscorrectly despite the log file entry.

CRI-909When using an Agilent 6890 GC system, the first time you click Load configuration from GC inthe pre-configuration utility, the configuration completes successfully. Clicking Loadconfiguration from GC again produces the error Failed to connect to 6890 at <IPaddress>.

Solution: Restart the GC and acquisition client.

CRI-1100The ICF Manual Injection function is not available in versions 3.1, 3.2, and 3.3 of the Agilent ICFSupport Layer.

Note: The ICF Manual Injection function is available when not configured with injectors.

Solution: None.

CRI-1043When the Agilent GS Flame Ionization Detector is out, the system records a flat baseline until theend of the sequence instead of triggering the Instrument failure error.

Solution: None.

CRI-1182In the Instrument Method Editor, in the Columns window, clicking Only Show Columns results ina Microsoft .NET Framework error.

April 29, 2020, 715006563 Ver. 00Page 39

Note: The issue occurs only with saved methods.

Solution: None.

CRI-1279In versions 3.1, 3.2, and 3.3 of the Agilent ICF Support Layer, the gas sampling valve does notfunction as expected when selecting GC_valve from the Preference Injector drop-down list.

Solution: None.

CRI-1280In versions 3.0, 3.1, 3.2, and 3.3 of the Agilent ICF Support Layer, in instrument methods, settingthe GC equilibration time to more than ten minutes results in an instrument failure. The sameissue occurs if the GC readiness time combined with the GC equilibration time take more than tenminutes.

Solution: None.

CRI-1284When a GC with Headspace Sampler 7697A or G1888 (without ALS injector) is connected to aLAC/E, while creating methods, the Options tab lists the injector twice, with both Front and Back.

Solution: Select the correct option depending on the instrument configuration (Front or Back)and start the injection.

CRI-1303On Agilent 6890 GC and Agilent 7890 GC, the following actions that configure how the systemhandles ALS errors do not work as expected: Pause for user interaction, Skip to the nextsample, Abort the sequence.

Solution: None.

CRI-1312Occasionally, the download of an Agilent LC Instrument Method fails and the following messageerrors appear:

• In the Message Center: Method download failed because instrument isoffline.

• In the Run Samples window: System Idle-Instrument Failure.

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Solution: None.

CRI-1383Upgrading from Agilent ICF Support version 3.1 to Agilent ICF Support versions 3.2 and 3.3deletes the configuration details in the host registry and, when running samples, results in aninstrument failure or a Server busy error.

Solution: To recreate the configuration details in the host registry after upgrade, delete theexisting MAC address, specify again the MAC address, and click Scan Instruments.

CRI-1548In versions 3.0, 3.1, 3.2, and 3.3 of the Agilent ICF Support Layer, you cannot configure theinstrument methods to run a needle wash in triplicate. The issue occurs with Agilent drivers.

Solution: None.

Note: Agilent ticket number for this issue is 209-66361.

CRI-1784When running an acquisition on an Agilent 6890 GC with an Agilent Headspace sampler, thesystem does not plot the channel data.

Solution: None.

Alternative: Use Agilent ICF Support Layer v3.2 with Agilent ICF A.02.05, which incorporatesGC driver version B.01.03a, on the acquisition client that controls the 6890 GC with the AgilentHeadspace sampler. In a mixed environment, all other Empower nodes, including Citrix servers,are supported with this upgrade.

See also: For an example of an ICF configuration in a mixed environment, see Drivercompatibility.

Note: Agilent documented this issue as 293241.

CRI-1821With Agilent ICF Support Layer v3.2 and v3.3, when running an acquisition on an Agilent GC withan Agilent Headspace Sampler, the Equilibrate and Condition Column functions lead toinstrument failure for both high throughput and low throughput modes.

Note: Running acquisitions on an Agilent GC with an ALS configuration works as expected.

Solution: None.

Alternative: Use the Equilibrate and Condition Column functions in a separate sample set.

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CRI-1953In an Enterprise environment, with a CTC PAL3 driver, the control panels from the Run Sampleswindow are not displayed.

Note: The issue does not occur on an Empower personal setup with a CTC PAL3 driver.

Solution: None.

INFICFSL-716With an Agilent LC system, in the Sample Set Method Editor, when using the equilibrate function,an Analysis aborted by another module error messages appears in the MessageCenter every time the system switches from the equilibrate to the inject function.

Note: The issue occurs when acquiring the data.

Solution: None.

INFICFSL-767In Run Samples, on the Instrument Method tab of the Instrument Method Editor window,clicking the graph Column #1 dotted line results in an Unhandled exception error.

Solution: • Right-click Graph View and select Only Show Oven Temperature.

• Right-click Graph View and clear the Only Show Oven Temperature selection.

• Click Graph View.

INFICFSL-768In the Instrument Method Editor, in the Columns window, when selecting Show InstrumentActuals, the system does not display the Read Back values of the GC.

Solution: None.

INFICFSL-773In the Instrument Method Editor, in the Signals window, when clicking Hide Dual Injection SignalAssignments, an Unhandled exception error occurs.

Solution: None.

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INFICFSL-786In the Instrument Method Editor, in the Miscellaneous window, when changing the pressure unitsand then saving the instrument method, the system incorrectly reverts to the previously selectedpressure unit. The system should retain the selection at least until the next power cycle.

Solution: None.

Issues addressed in this releaseThe issues listed in this section were addressed in this software version as described in theindividual issue description. Because these issues are not reproducible outside of the customerenvironment, Waters cannot verify the effectivity of the changes.

CRI-443Occasionally, when you ran a sample set on an Agilent LC Infinity II module, the Server busyerror message appeared in the Run Samples window when these conditions occur: the system istransitioning between sample rows while preparing for a run by downloading the method.

Note: The issue is fixed in Agilent ICF 2.6 Update 2, LC driver version A.02.19 SR2. Agilentdocumented this issue in their document entitled: "ICF 2.6 Update 2 Release Information" asdefect number 401099.

CRI-742Occasionally, for systems running Agilent ICF Support version 3.1, the AgilentPlugInServer stopsfunctioning with the Kernelbase.dll crash.

Note: A small memory leak was identified in Agilent driver version A.02.18. This issue wasresolved in Agilent driver version A.02.19 SR2 and included in Agilent ICF 2.6 Update 2. Thememory leak occurs in all autosamplers with thermostat controls when acquiring data fromautosampler channels.

Agilent PreConfiguration UtilityUse the Agilent PreConfiguration Utility to remotely configure a new system. Always launch theutility from the Empower Configuration Manager > Tools menu.

The PreConfiguration Utility connects to a LAC/E module using the module's IP address or hostname. You can select and configure the instruments you want to use and create a new systemthat contains the selected instruments.

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Note: To configure Agilent LC systems, search for the Tech Note "Using the AgilentPreConfiguration Utility with Agilent Instrument Control Framework (ICF) Support" on the Waterssupport site support.waters.com .

Configuring any type of Agilent GC using the PreConfiguration UtilityFollow this procedure to configure an Agilent GC using Empower's PreConfiguration Utility.

To configure an Agilent GC system using the PreConfiguration Utility:

1. Using the front panel of the GC instrument, set up the Agilent GC with a static IP address.

2. Log in to Empower from any client or through the Citrix server.

3. From Configuration Manager, click Tools > Agilent PreConfiguration.

4. In the Configuration Directory dialog box, type the host name or IP address of the LAC/Enode, and then click Connect.

Note: When you are connected to the node, the New button is enabled.

5. In the Configuration Directory dialog box, click New.

Note: Before you proceed to the next step, ensure that you are able to ping the IPaddress of the Agilent GC system from the LAC/E Command Prompt window.

6. In the Configuration Editor window, select Agilent 68xx/78xx/9000/88xx/7697/G1888 GC/HS., and then do the following:

• Expand 68xx/78xx/9000/88xx/7697/G1888 GC/HS.

• Select the instrument you want to configure.

• Click > to move the instrument to the right-hand pane of the Configuration Editorwindow, and then select it.

• In the right-hand pane of the Configuration Editor window, select the instrument, andthen click Configure.

7. In the Connection tab of the Configure dialog box, specify the IP Address, and thenclick Get GC Configuration.

8. In the Configuration tab of the Configure dialog box, specify or modify selections asneeded, confirm that the modules are read correctly, and then click OK to close the Configuration window.

Note: If you are adding a headspace sampler, proceed to step 4 in the Configuring a GCsystem to include a headspace sampler. Otherwise, click OK to close the ConfigurationEditor.

Result: The Configuration Directory lists the configured Agilent GC systems with theirappropriate IP addresses as the assigned names. If you are finished configuring GCsystems, click Exit to close the PreConfiguration Editor Utility. If not, repeat the procedure.

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https://support.waters.com/

Configuring a GC system to include a headspace samplerYou must use the Agilent PreConfiguration Utility to configure a headspace sampler with a GCsystem in Empower software. The headspace sampler is no longer listed as a separateinstrument in Empower software.

Note: The following procedure applies to a G1888A or an HS7697A headspace sampler.

To configure an Agilent GC system to include a headspace sampler using the PreConfiguration Utility:

1. Configure the Agilent GC system following this procedure: Configuring any type of AgilentGC using the PreConfiguration Utility.

2. From Configuration Manager, click Tools > Agilent PreConfiguration.

3. In the Configuration Directory dialog box, type the host name or IP address of the LAC/Enode, and then click Connect.

4. Using the front panel of the headspace sampler, set up the headspace sampler with astatic IP address.

Note: Before you proceed to the next step, ensure that you are able to ping the IPaddress of the headspace sampler from the LAC/E Command Prompt window.

5. In the Configuration Editor window, add the headspace sampler by following these steps:

• Select Agilent 68xx/78xx/9000/88xx/7697/G1888 GC/HS.

• Expand Agilent 68xx/78xx/9000/88xx/7697/G1888 GC/HS.

• Select the headspace sampler you want to configure.

• Click > to move the headspace sampler to the right-hand pane of the ConfigurationEditor window, beneath the GC in the list.

• Select the headspace sampler in the right-hand pane, and then click Configure.

6. On the Connection tab of the Configure dialog box, specify the headspace IP Address.

7. On the Configuration tab of the Configure dialog box, select Upload Config fromInstrument. Confirm that the information is correct in the Instrument, System, and Resource Conservation tabs. If not, modify as needed, and then click OK.

Result: The Configure dialog box closes.

8. In the Configuration Editor dialog box, click OK.

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Figure 1–4: Configuration Editor

9. After you configure the headspace sampler, only the GC and its IP address appear in the Configuration Directory dialog box. In the Configuration Directory dialog box, click Exit.

Figure 1–5: Configuration Directory

10. Continue with the next GC configuration topic.

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Configuring the GC system (with or without a headspace sampler) inEmpower

Once you finish creating the entry in the PreConfiguration Utility in Configuration Manger, youmust configure the Agilent GC system in Empower software.

To configure the GC system (with or without a headspace sampler) in Empowersoftware:

1. In the Configuration Manager window, select Nodes from the Empower 3 configurationtree, select the desired node from the table, and then right-click and select Properties.

2. In the Node Properties dialog box, select the Configure DHCP tab, and then click Configure DHCP.

3. In the Waters DHCP Server Configuration window, click Add.

4. In the Add IP Address dialog box, do the following, and then click OK:

• In the IP address field, specify the static IP address that you assigned to the AgilentGC. This must match the IP address assigned to the PreConfiguration Utility, which isdescribed in the previous section.

• In the MAC address field, specify the MAC address of the Agilent GC.

• In the Instrument type field, select AgGC.

• In the Serial Number/Unique Name field, type the serial number or the unique namethat is in accordance with your SOP.

Note: Even though you configured a headspace sampler using the Configuring a GCsystem to include a headspace sampler procedure, the Waters DHCP Server Configurationdialog box lists the GC instrument only and not the headspace sampler.

5. In the Waters DHCP Server Configuration dialog box, click OK.

6. In the Node Properties dialog box, select the Instruments tab, and then click ScanInstruments. The OK? column in the Instruments tab of the Nodes Properties dialog boxdisplays a value of Yes for the AgGC.

Note: Click OK to close the Node Properties dialog box.

7. Create a chromatographic system in Empower by following these steps:

• From the Configuration Manager window, right-click New > Chromatographic System.

• On the New Chromatographic System Wizard - Type Entry page, select Create NewSystem, and then click Next.

• On the New Chromatographic System Wizard - Select Server page, select theappropriate node, and then click Next.

Note: Even with a Headspace/GC system, there should be only one AgGC listed in theEmpower chromatographic system.

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• On the New Chromatographic System Wizard - System Selection page, select AgGCfrom the Available Instruments list (beneath Unused Components), drag it to the NewSystem Instruments pane, and then click Next.

• On the New Chromatographic System Wizard - Access Control page, select ShareSystem with other Network Users, select the appropriate Allow Access and AllowAccess to Groups settings, and then click Next.

• On the New Chromatographic System Wizard - Name Selection page, type a systemname and any system-related audit trail comments in the System Comment field.Ensure that the Online check box is selected, and then click Finish.

Result: A message informs you that the system is online and ready for use.

Note: You can confirm that the Agilent GC or Agilent GC/HS system is configured inEmpower by selecting the node in the Configuration Manager window, and then right-clicking Export to text. The Agilent GC or Agilent GC and HS configuration is exported toa text file. Review the text file output for accuracy.

8. From the Empower Log On window, select Run Samples, and then select the project andthe chromatographic system you created.

Options tab in the Instrument Method EditorUse the Options tab to select the throughput mode for the headspace injection and to indicateyour injection preference.

Note: The Options tab is available only if you configured headspace in the AgilentPreConfiguration Utility.

Throughput OptionsBy default, High Throughput is enabled. Use this option to perform single headspaceextractions.

To perform multiple headspace extractions, clear the High Throughput check box. Empowerconsiders this low throughput.

Tip: For throughput options, refer to the GC control considerations topic.

Injection PreferenceUsing Injection Preference, you can choose the injector as part of the instrument method, perthe PreConfiguration Utility.

Select the injector between ALS and Headspace from the drop-down list, as follows.

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Figure 1–6: Injector selection

Note: Here GC_Front represents front ALS and GC_Back represents back ALS.

Tip: When ALS is the preferred injector, the High Throughput becomes disabled.

Recommendation: Do not use different injection sources in the same sample set.

Dual tower supportAgilent ICF Support Layer v3.3 provides support for dual tower acquisitions. If two sequentialsample lines with both front and back injector vial numbers are present in the sample set, theyare eligible for dual tower parallel acquisition, but only if both lines specify the same InstrumentMethod/Method Set, number of injections, and Run Time.

Note: For dual tower support, configure the Gas Chromatography (GC) module with both frontand back autosampler tower.

Details for dual tower support:

• Installing Agilent ICF Support Layer v3.3 with the Legacy GC/HS driver might cause conflict.Do not use both legacy drivers and ICF Support in the same workstation.

• In Dual Tower mode, the vial numbers are defined using alphanumeric values:

F:1 Where “F” indicates the front tower and “1” is the vial number.

B:2 Where “B” indicates the Back Tower and “2” is the vial number.

• When Dual Tower mode is disabled, the vial numbering convention remains the same as inAgilent ICF Support Layer v3.1.

Scripts for dual tower supportScripts to enable and disable dual tower support are located at xxx\Build folder\UtilityScripts\DualTower You must run the scripts on all clients (including Citrix Server)and LAC/E nodes.

Important: To use the dual tower feature, you must uninstall legacy drivers.

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Enabling script for dual tower supportTo enable dual tower support on a client, use the "Enable_Dual_Tower.bat" script.

To enable dual tower support:

1. Navigate to the xxx\Build folder\UtilityScripts\DualTower folder.

2. Right-click Enable_Dual_Tower.bat and select Run as administrator.

3. Restart the client.

4. When you configure the DHCP, select the A7890 instrument type.

Note: The A7890 entry enables dual tower support for all GCs.

Important: If the system is configured with the AgGC instrument type, you must reconfigure theinstrument type as A7890 and re-create the system.

Disabling script for dual towerTo disable dual tower support from the registry, use the "Disable_Dual_Tower.bat" script.

To disable dual tower support:

1. Navigate to the xxx\Build folder\UtilityScripts\DualTower folder.

2. Right-click Disable_Dual_Tower.bat and select Run as administrator.

3. Restart the client.

Important: You must reconfigure the Instrument Type as AgGC and re-create the system, afteryou disable Dual Tower support.

Enabling dual tower support in EmpowerBy default, dual tower support for any GC is disabled.

To enable dual tower support in Empower:

1. Open Run Samples.

2. From the menu, choose Customize > Defaults.

3. In the dialog box, select 7890 is Dual Tower Instrument.

Tip: This Empower checkbox enables Dual Tower support for all GC instruments.

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Once dual tower is enabled, you can see three radio buttons in the Empower Run Sampleswindow.

Notes: • These radio buttons can be used to view the front sample lines, back sample lines, or both

front and back sample lines.

• The radio buttons have no impact on acquisition of the vials defined in the sample set; theymerely filter the sample set based on Front, Back, or Dual selection.

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Diagnostics log exportThe diagnostics logs are the logs and messages generated from the Empower Run Sample > Diagnostics Log window. These logs are generated for each instrument. Different instrumentshave their own set of logs, which you can find on their respective diagnostics tabs. Agilent ICFSupport Layer v3.2 and v3.3 let you export diagnostics logs into an external file fortroubleshooting.

Scripts to enable diagnostics log export are located in xxx\Build folder\UtilityScripts\DiagnosticLogExport.

Note: The diagnostics log option is disabled by default.

Enabling script for diagnostics log exportTo enable the export of diagnostics logs to an external file, use the Enable_Third_Party_Logs.bat script. Run this script on any LAC/E where you want loggingfor the systems on that LAC/E.

To enable the export of diagnostics logs:

1. Navigate to the xxx\Build folder\UtilityScripts\DiagnosticLogExportfolder on the LAC/E you want to change.

2. Right-click Enable_Third_Party_Logs.bat and select Run as administrator.

3. Restart the LAC/E.

Result: The logs then start generating and appear in the C:\Empower\Instruments\Log\<DHCPInstrumentName> folder with the filename Third_Party_Instrument_Logs_01.txt. If the file size exceeds the limit, Empowercreates a new file in the same folder with the filename Third_Party_Instrument_Logs_02.txt and the logs fromThird_Party_Instrument_Logs_01.txt will be backed up in the newly created file.The Third_Party_Instrument_Logs_01.txt file continues to collect the logs with therecent messages. The logs for each Instrument appear in their respective folders.

Disabling script for diagnostics log exportTo disable the export of diagnostics log to an external file, use the"Disable_Third_Party_Logs.bat" script. Diagnostics logs are enabled on the LAC/E connected tothe system.

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To disable the export of diagnostics logs:

1. Navigate to the xxx\Build folder\UtilityScripts\DiagnosticLogExportfolder on the LAC/E you want to change.

2. Right-click Disable_Third_Party_Logs.bat and select Run as administrator.

3. Restart the LAC/E.

Note: This disables the logs export.

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Documents

Agilent ICF Support Layer v3 · Support Layer v3.2 installed. Note: Agilent ICF Support Layer v2.2 and later is compatible with Waters Driver Pack 4 and later. GC control considerations