Abnormal Third Stage of Labour

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    POSTPARTUM HEMORRHAGE

    Definitions:

    Primary postpartum hemorrhage:

    Blood loss at delivery within 24 hours

    exceeding:

    Vaginal delivery: > 500 ml ( 500 ml isconsidered

    physiological)

    Cesarean delivery: > 1000 ml ( 1000 ml is

    considered

    physiological).

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    Secondary postpartum

    hemorrhage:

    Excessive blood loss > 24 hours

    and < 12 weeks postpartum

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    Etiology:

    Lack of efficient uterine contraction (uterine atony)

    commonest cause of primary PPH.

    Retained parts of the placenta.

    Vaginal or cervical lacerations. Uterine rupture rare.

    Clotting disorders, uterine inversion, or rupture

    extremely rare.

    Risk

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    Risk factors:

    Risk factors for primary PPH include first pregnancy,maternal obesity, a large baby, twin pregnancy, prolonged

    or

    augmented labor, and antepartum hemorrhage. High

    multiparitydoes not appear to be a strong risk factor, either in

    high- or low-income countries, even after controlling for

    maternal age. Despite the identification of risk factors,

    primary

    PPH often occurs unpredictably in low-risk women.

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    Complications:

    Hypovolemic shock, disseminated

    intravascular coagulation

    (DIC), renal failure, hepatic failure,adult respiratory

    distress syndrome, and death.

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    Management

    :Primary postpartum hemorrhage

    Obtain help (multidisciplinary approach).

    Vigorous uterine massage until firm.

    Identify and repair any vaginal and cervical lacerations.

    Place initial suture above the apex. Ensure adequateexposure; if necessary, transfer patient to surgical suite.

    Manually explore the uterus; ensure adequate intravenous

    (IV) access.

    Laboratory tests: complete blood count with plateletconcentration,

    blood type, antibody screen, fibrinogen, fibrin split

    products, prothrombin time, and partial prothrombin time.

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    Administer uterotonic drugs :

    1. Oxytocin 2080 IU in 1000 ml of normal saline

    (NS),fast IV drip, and/or

    2. Misoprostol 8001000 g rectally

    3. Methergine 0.2 mg intramuscular (IM) (if

    evidence ofhypertension do not administer) every 24 hours,

    and/or

    4. Carboprost tromethamine (Hemabate;

    prostaglandinF2 *PGF2+) 0.25 mg IM every 1590 minutes.

    Maximum dose is 2 mg (do not administer if asthma

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    Rectal misoprostol is a useful first-line drug for

    the treatmentof PPH. Compared with a combination of IM

    syntometrine

    injection and oxytocin infusion, rectal

    misoprostol 800 g is associated with astatistically significant

    reduction in the number of women who

    continued to

    bleed after the intervention and those who

    required medical

    co-interventions to control the bleeding.

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    During the administration of

    uterotonic agents, bimanualcompressionmay control

    hemorrhage. The physician

    places his or her fist in the

    vagina and presses on theanterior surface of the uterus

    while an abdominal hand

    placed above the fundus

    presses on the posterior wall.

    Thiswhile the Blood for

    transfusion made available.

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    suture bleeding sites.

    uterine artery ligation.

    B-Lynch stitch for uterine compression.

    Hysterectomy.

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    B-Lynch compressive sutures

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    Uterine Artery Ligation

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    RETAINED PLACENTA

    Definition:

    The placenta is undelivered at > 30 minutes

    after deliverydespite active management of the third

    stage.

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    Etiology: Preterm birth: incidence is inversely

    proportional to gestational

    age.

    Cord avulsion: incidence is 3% with controlled

    cord traction. Placenta accreta.

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    Complications:Hemorrhage

    infection,

    genital tract trauma

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    Management: Provide adequate anesthesia.

    Attempt manual extraction.

    Once placental margin is identified, gently peel the

    placenta from the uterine wall and remove it.May

    considerultrasound to ascertain if placental removal is

    complete.

    Palpate and massage the fundus until firm.

    injection of oxytocin (10 or 20 IU in 1 or2 ml) in NS (1819 ml) is effective in the management of

    retained placenta at 2030 minutes by decreasing the

    need for manual placental removal compared with NS

    alone or expectant management.

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    Removal of Abnormal

    Placenta

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    UTERINE INVERSION

    :Definition

    Collapse of the uterine fundusinto the endometrial cavity.

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    Risks:Excess cord traction.

    fundal pressure.

    fundal cord insertions.

    abnormal placentations.

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    Summon anesthesia and nursing staff.

    Provide large-bore access and IV fluid therapy.

    Withhold uterotonic agents.

    To decrease bleeding, avoid separating theplacenta.

    Consider pharmacological uterine relaxation:

    magnesium sulfate IV bolus

    terbutaline IV 0.25 mg subcutaneously 1 nitroglycerin 50500 g orally or by anesthesia

    Management

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    Manual manipulation of the uterus

    Rare surgical intervention (laparotomy) if cannot

    correctby vaginal manipulation alone:

    Huntington procedure clamps are placed on

    the round ligaments 2 cm deep in the inversion andgentle

    upward traction applied. Repeat clamping as

    necessary.

    Haultain procedure an incision is made in the

    posterior

    portion of the inversion ring to increase its size

    and to reposition the uterus.

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    Uterotonic agents when uterus repositioned:

    Oxytocin 2040 IU/L NS IV, Methergine 0.2 mgIM

    every 6 hours as needed, or Hemabate 0.25 mg

    IMrepeated every 2560 minutes as needed.

    Treat PPH or retained placenta as mentioned

    above.

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