THE STREM CHEMIKERA Publication of Strem Chemicals, Inc.

VOL. XXX No. 1 February, 2018

High Surface AreaSilica Nanoparticles

by Jean-Marie Basset and Pradeep Doggali

©Copyright 2018 by

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The Strem ChemikerVol. XXX No.1February, 2018

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American Chemical Society Award for Distinguished Service in the Advancement of Inorganic Chemistry

2018201720162015

Prof. Thomas B. Rauchfuss, University of IllinoisProf. William B. Tolman, University of MinnesotaProf. Vincent L. Pecoraro, University of MichiganProf. Kim R. Dunbar, Texas A&M University

Canadian Society for Chemistry Award for Pure or Applied Inorganic Chemistry

2018201720162015

Assoc. Prof. Eric Rivard, University of AlbertaProf. Dwight Seferos, University of TorontoProf. Curtis P. Berlinguette, University of British ColumbiaProf. Muralee Murugesu, University of Ottawa

Biographical Sketches:Prof. Jean-Marie Basset, Ph.D. ............................................................................Dr. Pradeep Kumar Doggali....................................................................................

12

Article 1: High Surface Area Fibrous Silica Nanoparticles (KCC-1) ............................ 3-23

High Surface Area Silica Nanoparticles Available from Strem............................. 24-25

New Products Introduced Since Chemiker XXIX (July 2016)............................... 26-99

New Kits Introduced Since Chemiker XXIX (July 2016)........................................ 101-110

AntPhos and WingPhos Kit .................................................................................BI-DIME Ligand Kit..............................................................................................Buchwald Biaryl Phosphine Ligand Mini Kit 3 for Aromatic Carbon-Heteroatom

Bond Formation, Suzuki Coupling and Negishi Cross-coupling.......................Buchwald Palladacycle Precatalyst Kit 2b (Methanesulfonato-2’-amino-1,1’- biphenyl-2-yl-Palladacycles Gen. 3)................................................................ CalB immo KIT™ - Immobilized enzyme..............................................................Enzyme carrier Lifetech™ ECRKIT1.....................................................................Graphene Quantum Dots (GQDs) Master Kit.......................................................Graphene Quantum Dots (GQDs) Mini Kit (Powders) .........................................Graphene Quantum Dots (GQDs) Mini Kit (Liquids) ............................................Lipase immo Kit - Immobilized enzymes...............................................................Solvias Josiphos Nickel Catalyst Kit ....................................................................

101102

103-104

105-106107107108108109109110

Available Booklets..................................................................................................... 112

Table of Contents

Glossary of Terms[α]D

AASACS

air sensitive

ampb.p.

d.dec.

elec. gr.f.p.

gran.heat sensitive

hydratehygroscopic

light sensitiveliq.

m.p.moisture sensitive

NMR gradeoptical grade

pwdr.primary standard

PURATREMpurified

P. Vol.pyrophoric

reagent

REO

SAstore cold

subl.superconductor grade

tech. gr.TLCv.p.xtl.

..........

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Specific rotationAtomic Absorption StandardConforms to American Chemical Society specificationsProduct may chemically react with atmospheric oxygen or carbon dioxide at ambient conditions. Handle and store under an inert atmosphere of nitrogen or argon.AmpouledBoiling point in °C at 760mm, unless otherwise notedDensityDecomposesElectronic Grade, suitable for electronic applicationsFlash point in °FGranularProduct may chemically degrade if stored for prolonged periods of time at ambient temperatures or higher. Store at 5°C or lower.Unspecified water content which may vary slightly from lot to lotProduct may absorb water if exposed to the atmosphere for prolonged periods of time (dependent on humidity and temperature). Handle and store under an inert atmosphere of nitrogen or argon.Product may chemically degrade if exposed to lightLiquidMelting point in °CProduct may chemically react with water. Handle and store under an inert atmosphere of nitrogen or argon.Suitable as a Nuclear Magnetic Resonance reference standardFor optical applicationsPowderUsed to prepare reference standards and standardize volumetric solutionsProduct has a minimum purity of 99.99% (metals basis)A grade higher than technical, often used where there are no official standardsPore volumeProduct may spontaneously ignite if exposed to air at ambient conditionsHigh purity material, generally used in the laboratory for detecting,measuring, examining or analyzing other substancesRare Earth Oxides. Purity of a specific rare-earth metal expressed as apercentage of total rare-earths oxides.Surface areaProduct should be stored at -18°C or 4°C, unless otherwise noted (see product details)SublimesA high purity, analyzed grade, suitable for preparing superconductorsTechnical grade for general industrial useSuitable for Thin Layer ChromotographyVapor pressure mm of HgCrystalline

Chemical purityMetals purity

..........

..........is reported after the chemical name, e.g. Ruthenium carbonyl, 99%is reported in parentheses with the respective element, e.g. Gallium (III) bromide, anhydrous, granular (99.999%-Ga) PURATREM where100% minus the metal purity is equal to the maximum allowable percentage of trace metal impurity

About Purity

1

Biographical Sketches

Prof. Jean-Marie Basset, Ph.D.

Prof. Jean-Marie Basset is a Distinguished Professor in the Physical Sciences and Engineering Division at King Abdullah University of Science & Technology (KAUST). From his start at KAUST in 2009 until October 2017 he served as Director of the KAUST Catalysis Center (KCC) of which he was also a founding member. He continues his work today at the KCC in Chemical Science.

Catalysis is a strategic domain for the world and particularly Saudi Arabia. It is a critical enabling science for the Kingdom’s energy future. Improvement in catalytic processes across the chemical and petroleum industries will increase resources, energy utilization efficiencies and reduce waste. The need for breakthroughs within

the crucial domains of catalysis are imperative to meet the energy challenges “beyond petroleum” such as the use of CO2 Natural Gas, CO utilization, and efficient photocatalysts for water splitting. Prof. Basset has been working to meet some of these challenges and help to catalysis field to advance from catalyst discovery to catalysis by design. He has recently developed a theory to predict any catalytic reaction on the basis of the catalysis by design using single site catalysis.

Before his move to KAUST, Prof. Basset served as the Research Director at the Centre National de la Recherche Scientifique (CNRS) since 1987. He first came to CNRS in 1971 and occupied several positions in his tenure including vice-director of the Institute of Catalysis (Lyon). He founded the consortium “Actane” on alkane activation with 11 university labs and 5 different companies. He founded his Laboratory of Surface Organometallic Chemistry in 1994. During this time he was also acting Scientific Director of the School of Chemistry, Physics and Electronics (CPE) at the University of Lyon in France (1992-1994). Prof. Basset’s Lyon lab was home to over 50 scientists, including Nobel Laureate Yves Chauvin. This lab has trained over 450 chemists through three- year scholarship programs.

He has written more than 600 publications in international journals and holds 70 patents most of which are protected internationally.

Prof. Basset’s achievements include: ▫ 2011 Member of the European Academy of Sciences and Arts (AUS) ▫ 2008 Doctor Honoris Causa, University of Xiamen (CN) ▫ 2008 Doctor Honoris Causa, TUM (DE) ▫ 2006 Augustine Award of the ORCS (USA) ▫ 2005 Distinguished Achievements Award of IMPI (USA) ▫ 2003 Chevalier dans l’Ordre National du Mérite (FR) ▫ 2003 Member of the European Academy of Sciences (EU) ▫ 2002 “Visiting Professor University of Hokkaido” (JAP) ▫ 2001 Member of the French Academy of Technologies (FR) ▫ 1999 “August-Wilhem-Von-Hofman-Vorselung” Lecturer (DE) ▫ 1998 Academy of Sciences Award, Prix de l’Institut Français du Pétrole (FR) ▫ 1998 Seaborg Lecturer in Inorganic Chemistry (Université de Berkeley) (USA) ▫ 1997 Procope Award for French –German collaboration (FR) ▫ 1997 Société Française de Chimie (Grand Prix) Prix Süe 1997 (FR) ▫ 1993 Corresponding member of the de French Academy of Sciences (FR) ▫ 1992 Grammaticakis Neuman Award of the French Academy of Sciences (FR) ▫ 1991 Max Plank Award with W. Herrmann (DE) ▫ 1987 Japan Society for the Promotion of Sciences Award (JAP) ▫ 1987 Alexander Von Humboldt Award (DE) ▫ 1984 Pacific Coast Lecturer West Coast (USA)

2

Dr. Pradeep Kumar Doggali

Dr. Pradeep Kumar Doggali is a Postdoctoral Fellow at King Abdullah University of Science and Technology (KAUST), Saudi Arabia. He completed his Master of Science in Chemistry (Specialization: Industrial Chemistry) in the year 2007 from Jawaharlal Nehru Technological University (JNTU), Hyderabad, India. That same year, he joined the National Environmental Engineering Research Institute (NEERI), a laboratory of Council of Scientific and Industrial Research (CSIR) in India to pursue his doctoral studies. His research work focused on developing Perovskite and Mixed Oxide type catalytic materials for coal combustion and post combustion control of carbon monoxide (CO) and particulate matter (PM) emissions. During his Ph.D. studies, he was

on deputation to Kyushu University, Japan as a visiting research student (2009) at the Laboratory of Prof. Y. Teraoka. There he worked on transition metal-based perovskite type catalysts for the control of diesel soot emissions from vehicles and stationary sources like generator sets. In 2012 he joined the R&D unit of Larson and Toubro (L&T) Power Limited (Vadodara, India) as a Research Executive. At L&T, Dr. Doggali contributed in the development of suitable biomass additives for the clean combustion of coal for gasification based systems.

As a Research Consultant in KAUST (2013), he worked on developing shape, size and morphology controlled nano structured metal oxides and mixed oxides using template assisted routes. Dr. Doggali’s postdoctoral work (2015) is primarily in the area of developing improved methods to synthesize Nano Fibrous Silica (KCC-1) to make it suitable for a variety of industrial applications. He is also developing various nanoparticle supported KCC-1 based catalysts for different reactions of significance for use in energy and environmental fields. He was conferred with DST (Department of Science and Technology), India, Young Scientist award in the year 2015.

Awards: ▫ GLOBAL-COE Internship Award at Kyushu University, Japan ▫ Best business plan presentation award at Technology Led Entrepreneurship Program of Indian Institute of Chemical Technology (CSIR-IICT) by the faculty of Indian Institute of Management (IIM) ▫ Best Oral presentation award on “Enviro 2025-Challenges, Interventions & Mitigations” held at NEERI, Nagpur, India. ▫ Awarded Senior Research Fellowship (SRF) by CSIR (Council of Scientific and Industrial Research, Government of India).

Biographical Sketches

3

High Surface Area Fibrous Silica Nanoparticles (KCC-1)Jean-Marie Basset and Pradeep Doggali

KAUST Catalysis Center4700 King Abdullah University of Science & Technology (KAUST),

Thuwal 23955-6900, Saudi Arabia

IntroductionGiven the growing demand for silica materials for various applications including catalysis, drug delivery, bio sensing, liquid chromatography, coating & paints, optically active materials, as well as in cosmetics, much research has been carried out to control the shape, structure, and pore-size leading to various types of mesoporous silica materials. However, the performance, and therefore the applicability, of mesoporous silica has been hindered by the limitation in accessibility to the active sites within the porous structure for many reasons, such as clogging of the pores by the sintering of active metals and also by accumulation of the carbonaceous by products inside the pores or at the external surface of porous materials. The morphology of the mesoporous silica could also influence the way drugs gets encapsulated and their subsequent release. Therefore, development and fabrication of novel silica materials with unique morphology that leads to high performances, which results in super efficiency is imperative to meet the emerging applications.

KAUST’s novel fibrous silica nanospheres (KCC-1)[1] offers a unique alternative shape, other than porosity, that has never before been seen in silica materials: a fibrous surface morphology arranged in three dimensional structure to form spheres. Unlike traditional pore-based silica, these nanospheres possess a fibrous structure that increases accessibility to most of the available surface area; this, for example, increases catalytic activity significantly. KCC-1 has been attracting the attention of researchers all over the world owing to its unique morphology and high surface area and therefore, making it ideal for use in a wide variety of catalytic reactions, sorbent and biological applications such as immobilization of enzymes and delivering DNAs.

A range of Nano catalysts synthesized using KCC-1 as a support have been showing excellent catalytic activity for various reactions of industrial importance. As a catalyst support/sorbent/carrier, KCC-1 has been demonstrating superior activity as compared to commercially available mesoporous silica materials such as MCM-41 and SBA-15. Some of these KCC-1 based materials and their corresponding reactions are included in Table.1.

S.N KCC-1 based material/catalyst/sorbent

Catalytic reaction/sorbent application/ carrier for DNAs and genes Reference

1. Tantalum hydride catalyst supported on KCC-1 Hydrometathesis of olefins 2

2. Ruthenium (Ru) nanoparticles supported on KCC-1 Hydrogenolysis of Propane 3

3. KCC-1 based silver nanocatalyst Hydrogenation of dimethyl oxalate (DMO) 4

4. Amine-functionalized KCC-1 CO2 Capture 5

5. Nitridated KCC-1 Knoevenagel condensation and transesterification 6

6. KCC-1 nanospheres CO2 methanation 7

7. KCC-1 supported Ag catalysts CO oxidation 8

8. Palladium nanoparticles supported on KCC-1

hydrogenation of alkenes and α,β-unsaturated carbonyl compounds 9

9. KCC-1 nanoparticles Synthesis of triazolo[1,2-a] indazole-triones 10

10. Manganese (Mn) incorporated KCC-1 catalytic ozonation of oxalic acid 11

11. Amine-grafted KCC-1 As a carrier to transport and deliver DNAs & genes 12

12. Atomic layer deposited (ALD) TiO2 on KCC-1 Photocatalytic dye degradation 13

Table 1.

4

Our group at catalysis research center (KCC) of KAUST has been working on catalytic applications using KCC-1 for different reactions. Successful attempts have been made in studying KCC-1 based catalysts for olefin and alkane metathesis, C-C Coupling, H2 production from natural gas, oxidation reactions and photocatalytic water splitting. Our research work on above mentioned application using KCC-1 is briefly discussed.

I) Hydro-metathesis of olefinsHydro-metathesis is a catalytic reaction of transition metal hydride, which in the presence of hydrogen catalyzes the direct conversion of olefins into alkanes having higher and lower numbers of carbon atoms. In this work, Tantalum hydride grafted on KCC-1 transforms an olefin in the presence of hydrogen at moderate temperatures into the expected corresponding alkane, and also transforms the same olefin into alkanes having a higher and lower number of carbon atoms. The catalytic hydro-metathesis of propylene (1:1 mixture of olefin and hydrogen) was performed and compared with 1-butene hydro-metathesis on a micropilot equipped with a stainless steel reactor at atmospheric pressure at 150°C . The reactions proceeded efficiently with 37–40% conversion of propylene and 48-51% of 1-butene. In the case of propylene, in addition to the expected hydrogenation product propane, butane (35–40%) and ethane (40%) were the major products formed, with methane, iso-butane, and pentanes as the minor products. In case of 1-butene, major products formed include butane, propane (47–61%) and hexanes (13– 25%) whereas ethane, propylene, pentanes, and heptanes formed as minor products. Remarkably, in both cases catalyst possessed high stability and regeneration ability[2]. Graphical representation of the process is presented below.

II) Hydrogenation of alkenesHydrogenation of alkenes and α,β-unsaturated carbonyl compounds have been studied using an efficient KCC-1 based catalyst (palladium nanoparticles supported on KCC-1). This resulted excellent yields of the corresponding products with very high chemo-selectivity in the case of α,β-unsaturated carbonyl compounds. We have observed the superior performance of KCC-1 in comparison with commercial mesoporous silica supports like MCM-41 and SBA-15 under identical conditions. These results are attributed to superior accessibility of catalytically active sites along with high loading and excellent dispersion of palladium in case of KCC-1[10].

O

Ph Ph

O

Ph Ph Ph Ph

Pd/KCC-1

hydrogenation

1,3-diphenyl-2-propene-1-one 1,3-diphenyl-2-propane-1-one Butane-1,3-diyldibenzene

+

III) Influence of metal particle (Au nanoparticles) size on catalytic CO oxidation In order to study the possible advantage of using the fibrous nature of KCC-1, we synthesized gold nanoparticles (Au NPs) with different size and supporting them on KCC-1. The activity of the resulting catalysts was and tested for CO oxidation reaction. It is evidenced by the HR-TEM studies that the size and the location of the Au NPs on the support observed to be dependent on the method of synthesis. The catalytic activity of the Au NPs proved to be size dependent. We have also observed that larger Au NPs of Au/KCC-1- NH2 were not able to penetrate the pores of KCC-1 and showed only limited catalytic activity. In this study, it was possible to place highly dispersed Au NPs with uniform size inside the fibers of KCC-1-NH2 by grafting HAuCl4 on Au/KCC-1-NH2 followed by reduction[14].

Tantalum Hydride grafted KCC-1

Lower Hydrocarbons Higher Hydrocarbons

Industrial Pollutants Fuels

5

IV) Coupling of methane to ethane and hydrogen We have developed a method to selectively produce hydrogen and ethane from methane by thermocatalytic decomposition of methane using Ru nanoparticles supported on Nano fibrous Silica (KCC-1) catalyst. These catalysts have been synthesized by post modification of KCC-1 with amine groups using APTS (3-aminopropyl triethoxysilane) followed by supporting nanoparticles on KCC-1. In this work, suitable temperatures and pressures have been found to produce a product having either hydrogen with solid carbon or ethane with solid carbon. The novelty of this approach also associated with the catalyst system that is efficient to produce the hydrogen and ethane as mentioned above with feed gas comprising less than 1000 ppm water. Also, the formation of hydrogen and ethane has not produced carbon dioxide (CO2) but a just carbon. Based on the structure of the carbon (formed in this reaction), it can have applications as carbon graphite/ carbon fiber/ carbon nanotube[15].

V) Photocatalytic water splittingWe have also been successful in utilizing fibrous nature of KCC-1 for photocatalytic reactions. Triazine-based carbon nitride (CN) synthesis in the presence of KCC-1, resulted in favorable effects to advance photocatalytic stability. The photocatalyst synthesized using this approach yielded a HER photocatalyst with a significant AQE of 22.1 ± 3% at 400 nm for solar to HER. The improved lifetime for the ground-state bleaching of the excited charge carriers was evidenced by time-resolved transient absorption spectroscopy. The synthesized CN/KCC-1 photocatalyst has been consistent with the higher photocatalytic performance than that of CN without KCC-1[16].

Solar Energy

Triazine basedcarbon nitride/KCC-1 catalyst

H2O H2 + 1/2 O2

Experiments are also in progress to test KCC-1 for different industrially important reactions considering its superior performance as compared to conventional silica supports.

Several researchers all over the globe have successfully utilized KCC-1 for various applications after our discovery of KCC-1 in 2010. Therefore, work carried out by research groups from other institutions has been discussed to sum-up the highlights of some potential applications of KCC-1.

VI) Hydrogenation of dimethyl oxalate (DMO) to Methylene Glycol (MG)Mengyao Ouyang et al. studied Ag/KCC-1 nanocatalyst for hydrogenation of dimethyl oxalate (DMO) to Methyl Glycolate (MG) and they compared the activity of Ag/KCC-1 with Ag/SBA-15 and Ag/MCM- 41. The results showed that dispersion of metals was completely dependent on the nature silica support used, which results in different dispersion and accessibility of active sites. Authors concluded that KCC-1 with hierarchical pore channels has higher accessible internal surface area and therefore displays high catalytic activity[4].

6

O

O

O

O HO

O

Omethyl glycolate

dimethyl oxalate

Ag/KCC-1 catalyst

H2

VII) Hydrogenation of functionalized aromatic compoundsM. Dhiman et al. synthesized ultrasmall platinum (Pt) nanoparticles on PEI (polyethylenimine) functionalized KCC-1 (KCC-1-PEI/Pt) and studied their activity for hydrogenation of 3-nitrostyrene. Authors observed an extraordinary selectivity for the said reaction and Pt (1%) supported on PEI functionalized KCC-1 was found to be selective towards reduction to 3-vinylaniline. On the other hand, 10% and 5% Pt loaded on KCC-1-PEI demonstrated high activity and selectivity towards 3-ethylaniline. It was observed that among studied catalysts KCC-1-PEI/Pt (1%) was found to be an efficient catalyst for the hydrogenation of a variety of substituted aromatic compounds. From obtained results it was described, how selectivity can be tuned just by changing the particle size of Pt nanoparticles. In this study, most active sites were observed to be subnanometer particles and pseudo-single atoms of Pt [17].

NH2

3-nitroaniline

NO2

NH2

CH2

3-vinylaniline

Pt/KCC-1

X. Le et al. investigated palladium supported KCC-1 catalyst for reduction of nitrophenols (4-NP) and hydrodeclorination of chlorophenols (4-CP). In order to synthesize catalysts, Pd precursor was added the functionalized KCC-1 followed by reduction with NaBH4. The Pd nanoparticles were well dispersed on fibers of KCC-1 and showed good catalytic activity for both the reactions. The higher catalytic activities was explained on the basis of morphological characteristics of the support which favors uniform dispersion and accessibility to Pd nanoparticles[18].

4-nitrophenol

NO2

OH

4-aminophenol

Pt/KCC-1nanocatalyst

OH

NH2

NaBH4

1-chloro-4-nitrobenzene

NO2

phenol

Pt/KCC-1nanocatalyst

Cl

HO

H2

In another one of their studies, X. Le et al. have explored magnetically retrievable core-shell catalyst Pd/Fe3O4@SiO2@KCC-1. The catalytic performance of the synthesized catalyst was determined by reduction reaction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP). The reduction rate was more for Pd/Fe3O4@SiO2@KCC-1 as compared to Pd on other supports. The catalyst was also tested for Suzuki coupling reaction and found to have good stability and reusability (up to five cycles)[19]. M. Dhiman et al.

7

reported a facile way for synthesis of metal nanoparticles (Rh, Ru, Pd) supported on KCC-1, wherein they used PEI as a pseudochelator. Their studies revealed that the use of PEI had an edge over complex dendrimer, making the process relatively inexpensive. The catalytic activities of synthesized catalysts (KCC-1-PEI/Rh, KCC-1-PEI/Ru, and KCC-1-PEI/Pd) were tested for hydrogenation of phenylacetylene and styrene. The activity of KCC-1-PEI/Rh was more for both hydrogenation of phenylacetylene and styrene, as compared to that of KCC-1-PEI/Ru, and KCC-1-PEI/Pd. The difference in the activity of these catalysts was attributed to varying adsorption coefficients for the different metal atoms. The higher activities exhibited by studied catalysts was explained on the basis of easy accessibility to metal atoms with KCC-1 despite PEI infiltration. KCC-1-PEI/Rh and KCC-1-PEI/Ru also showed excellent stability, which was maintained almost up to five cycles without any deterioration[20].

X. Le et al. also Studied Ni@Au core–shell nanoparticles supported KCC-1 for the reduction of 4-nitrophenol to 4-aminophenol in the presence of NaBH4. The examined catalyst showed superior catalytic activity in comparison with to Ni@Au NPs. This was explained by the high accessibility provided by KCC-1 and also due to the less aggregation of Ni@Au NPs on the KCC-1 nano-silica support. The Ni@Au/KCC-1 was also found to be an excellent catalysts to reduce 2-nitroaniline to o-Phenylenediamine. In this study, Ni@Au NPs as the active sites reduced the use of Au content not effecting the catalytic activity. Also possess paramagnetic nature, which makes the catalyst easy to recover for reuse. Authors have also shown that Ni@Au/KCC-1 can be reused at least ten times without significant reduction in catalytic activity. The sustainable activity was attributed to the inhibition of leaching of Ni@Au NPs from the mercaptopropyl groups functionalized KCC-1[21].

4-nitrophenol

NO2

OH4-aminophenol

Ni@Au/KCC-1nanocatalyst

OH

NH2

VIII) C-C bond forming reactionsSeveral research group have demonstrated use of KCC-1 for various catalytic reactions including, Suzuki coupling[22], Suzuki–Miyaura cross-coupling[23], Knoevenagel Condensation[6] and also synthesizing various industrially important organic compounds.

Fihri et al. investigated Pd nanoparticles supported KCC-1 for Suzuki coupling of aromatic halides. In order to prepare the catalysts, KCC-1 was first functionalized with amine groups using 3-aminopropyltriethoxysilane to obtain KCC-1-NH2. Later, the functionalized surface was treated with PdCl2 to prepare KCC-1-NH2/Pd. Authors found that the synthesized catalyst was active for different aryl bromides and iodides with aryl boronic acids and demonstrates good to excellent yields. It was possible to easily recover the catalyst from the reaction mixture and researchers reused it for a number of cycles with no significant change in the catalyst activity. Thus authors confirms the heterogeneity and good stability of this catalyst system. TEM investigations carried out in this study indicates no change in the morphology of fresh and used catalyst, which indicated no Ostwald ripening[22].

8

R1 = H, NO2, CN, MeCO, Cl, OHX = I, Br

Aryl bromides

biphenyl derivatives

Pd supported on KCC-1R1 X R2 B(OH)2

R2 = H, OMe

Aryl boronic acid

+

R2

R1

P. Gautam et al. synthesized palladium nanoparticles (Pd NPs) supported on KCC-1 and developed an economically viable and sustainable protocol for the carbonylative Suzuki–Miyaura cross coupling reaction. Pd nano particles supported on KCC-1 demonstrates the turnover number (TON) 28- times and a turnover frequency (TOF) 51-times greater than the best Palladium supported catalyst reported for the carbonylative cross-coupling between 4-iodoanisole and phenylboronic acid. Catalysts tested in this study could be recycled up to ten times with negligible loss in activity till eighth cycle[23].

Iodo benzenederivatives

biphenyl derivatives

Pd supported on PEIfunctionalized KCC-1 catalyst

R1

I

R2

B(OH)2

Phenyl boronic acidderivatives

+

R1 R2

O

IX) Knoevenagel condensationM.Bouhrara et al. synthesized Nitridated KCC-1 (solid base) by ammonolysis under a flow of ammonia (NH3). It was found that the synthesized catalyst is highly active for Knoevenagel condensation reactions of different aldehydes. Tested catalysts in this research work were active for the transesterification of esters with a wide range of alcohols compared to the reported catalysts. Authors explained the improvement in activity by the presence of both basic (amines) and acidic (silanols) sites and more importantly excellent accessibility of these sites in case of KCC-1. The unique structure of KCC-1 assists the substrates to easily penetrate and interact with basic amine and helps in improving the catalytic activity[6].

Benzaldehyde derivatives Knoevenagel condensed product

Nitridated KCC-1

R

Active methylene compounds

+

O

H

X

XR

X

X

X) Synthesizing different organic compoundsS.M. Sadeghzadeh explored KCC-1 based catalysts for construction of different organic compounds. Author reported a green and efficient method for synthesis of various triazolo [1,2-a]indazole-triones using KCC-1 catalyst at room temperature under solvent free conditions by visible light. Nano-SiO2, MCM-41, SBA-15 were also tested for synthesis of triazolo [1,2-a]indazole-triones using the same conditions. It was observed that the yields of the desired product was fair to good with Nano-SiO2, MCM-41, SBA-15. However, KCC-1 shows excellent yields for the same reaction. Non-negligible activity observed using KCC-1 was explained based on its shape, composition and morphology[10].

O

Odimedone

H

O

R1

benzaldehyde

HN

HNN

O

O

4-phenyl-1,2,4-triazolidine-3,5-dione

+ +N

N

N

R1O

triazolo[1,2-a]indazole-triones

O

O

Free KCC-1Visible light

Solvent freer.t.

9

In a different study, S.M. Sadeghzadeh synthesized ionic liquid functionalized KCC-1 and their activity was tested for the synthesis of quinazoline-2,4 (1H, 3H)-diones from CO2 and 2-aminobenzonitriles under mild conditions. Author compared the catalytic performance of ionic liquid functionalized KCC-1 and literature reported catalysts. Results in this study clearly indicate that the synthesized catalysts show good to excellent yields at lower temperature with small amount of catalyst, lower pressure of carbon dioxide and shorter reaction time. The synthesis was shown to be green, low-cost and was effective for the development of other materials[24].

NH2

2-aminobenzonitrilesR CN

+ CO2

KCC-1 supported ionicliquid (KCC-1.IL)

HN

NH

O

Oquinazoline-2,4(1H,3H)-dione

R

The author also investigated Fe3O4/KCC-1/BPAT MNPs core–shell nanocomposite for the synthesis of N-substituted 1,4-dihydropyridines with excellent yield under mild reaction condition. It was found that the studied catalyst was non-toxic, green and economically viable and recyclable for the synthesis of N-substituted 1,4-dihydropyridines[25].

NH2

Aniline derivatives

R1

CO2Me

CO2MeR

O

CO2Me

N

R

R1

MeO2C

MeO2C CO2Me

+ +

Cinnamic esters Di substituted Alkynes

N-substituted 1,4-dihydropyridines

Fe3O4/KCC-1/bis(4-pyridylamino)triazine (BPAT) catalyst

P. K. Kundu et al. studied KCC-1-PEI/Pd catalysts for decarbonylation of aldehydes, wherein they developed an efficient heterogeneous catalytic protocol for the decarbonylation of a variety of aldehydes with complete conversion to products. By doing this, authors have found an easy way for product purification (without chromatography) using KCC-1-PEI/Pd catalyst. The developed method in this study not only limited to aromatic aldehydes, but the decarbonylation of hetero aromatic, alkane, and alkenylaldehyde derivatives. Authors found that the studied catalyst have excellent recyclability even after eightcyles, which proves the sustainability of the studied catalyst system[26].

CHO

2-naphthaldehyde

H

naphthalene

Pd supported on PEIfunctionalized /KCC-1

S. Sadeghzadeh synthesized palladium nanoparticles (Pd NPs) dispersed on KCC-1 functionalized with different groups such as APTPOSS@KCC-1, hyperbranched polyglycerol@KCC-1 (HPG@KCC-1), and ionic liquid@KCC-1 (IL@KCC-1). These catalysts are evaluated for synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-one. It was observed that APTPOSS@KCC-1 displayed good catalytic

10

reaction and also exhibited excellent reusability in the catalytic reaction. The high activity of APTPOSS functionalized KCC-1 was attributed to its high accessibility and minimum aggregation. Also its tolerance to leaching of the nanoparticles[27].

O

OEt

O

ethyl 3-oxobutanoate

HN

NH2

Phenyl hydrazineR

++

R1

N

N

O

benzo[c]pyrazolo[1,2-a]cinnolin-1-one

R

R1

Pd/A@KCC-1

(A=APTPOSS, HPG, and IL) NPs

XI) Adsorbent for CO2 captureU. Patil et al. studied the use of silicon oxynitrides as adsorbents for CO2 capture. In this investigation authors synthesized three series of functionalized materials based on KCC-1, SBA-15 and MCM-41 with Si–NH2 groups in a single step process via thermal ammonolysis. Authors demonstrates that studied materials overcome several limitations associated with conventional aminegrafted mesoporous silica. Adsorbents prepared by ammonalysis shows good CO2 capture capacity, faster adsorption–desorption kinetics as well as effective regeneration and reuse. Also the studied materials demonstrate excellent thermal and mechanical stability[28]. Graphical representation of the process is presented below.

ThermalAmmonolysis

KCC-1 Silicon oxynitrides of KCC-1

Adsorbents forCO2 capature

B. Singh et al. synthesized KCC-1 based hybrid materials functionalized by different amine molecules using physisorption and covalent attachment. Synthesized materials were tested for their CO2 capture capacity. Among the studied materials, the tetraethylene pentamine (TEPA) based KCC-1 (KCC-1-TEPAads) showed superior capacity in comparison with MCM-41 in terms of textural stability, CO2 capture capacity, rate of adsorption as well as thermal stability. KCC-1-TEPAads demonstrates the adsorption capacity of 91.5 mmol g-1, whereas MCM-41-TEPAads CO2 capture capacity was observed to be only 73.1 mmol g-1. These results clearly indicate the superior stability of the KCC-1-based sorbents as compared to the conventional mesoporous materials[5]. Graphical representation of the above mentioned process is shown below.

Functionalizationwith Tetra Ethylene Pentamine (TEPA)

KCC-1 TEPA functionalized KCC-1

Adsorbents forCO2 capature

XII) Biological applications like immobilization of enzymes and DNA adsorption studiesZafar Ali et al. also studied the immobilization of lipase on KCC-1. Author’s method of synthesis, activation, and optimization of immobilization conditions, produced better resistance to temperature and pH inactivation as compared to the free lipase. Therefore, it widened the reaction pH and temperature regions, with the optimum pH and temperature of 7.5 and 40◦C, respectively. The immobilized Lipase i.e Candida Ragusa (ICRL) showed above 81% of the initial activity even after 28 days. Also 80% activity after 8 repeated cycles. Authors also demonstrated the ICRL improved storage stability, reusability as well as 700 U/g of protein as immobilization efficiency[29]. Graphical representation of Immobilization of enzyme on KCC-1 is shown below.

11

Xiaoxi Huang et al. performed DNA adsorption studies on a series of KCC-1- and MCM-41-based nanomaterials that are functionalized with organoamine groups. Authors observed higher adsorption capacities for KCC-1 based materials as compared to MCM-41 based nanomaterials. It was explained that DNA adsorption reaches saturation once the outer surfaces of the MCM-41 nanoparticles are occupied by the DNA molecules, leaving their inner channel spaces to play negligible role in the adsorption of DNA molecules. However, due to the unique fibrous morphology, KCC-1-based nanomaterials absorb DNAs efficiently both on their external and internal surfaces. Cellular toxicity tests performed in this study demonstrates the biocompatibility of KCC-1[12]. Graphical representation of DNA adsorbed KCC-1 is shown below.

XIII) Photo catalysisBayal et al. also reported a new method to fabricate TiO2 on the fibers of KCC-1. The synthesized KCC-1/TiO2 photocatalyst showed a very high yield of H2 (26.4 mmolh-1g-1 TiO2) in presence of UV light. The yield reported in this research study was one of the best reported so far for photocatalytic H2 generation. In addition, authors do not observe decrease in photocatalytic activity of KCC-1/TiO2, unlike conventional mesoporous silica materials and this effect was attributed to open morphology of KCC-1[30].

Solar Energy

TiO2 coatedKCC-1 nanocatalyst

H2O H2 + 1/2 O2

R. Singh et al. designed and synthesized KCC-1 based photo catalysts by coating TiO2 on fibers of KCC-1 using atomic layer deposition (ALD). Catalysts developed by authors showed superior catalytic activity for photocatalytic dye degradation in comparison to MCM-41 and SBA- 15 based TiO2 catalysts synthesized with aid of ALD as well as literature reported silica-supported TiO2 catalysts. Authors have described the advantages of KCC-1/TiO2 catalysts over MCM-41 and SBA-15 based TiO2. Some of these include uniform and conformal coating, less reduction in surface, enhanced light harvesting properties and better accessibility of active sites[13].

Solar Energy

TiO2 coatedKCC-1 catalyst(ALD technique)

H2O H2 + 1/2 O2

12

XIV) Optical sensing properties KCC-1 has been also explored as sensor with optical sensing properties and is used for detection of Hg2+ detection with very good selectivity, and sensitivity. The sensor was developed by immobilizing the rhodamine-based receptor (RB-Si) within the fibers of KCC-1. Authors observed that spirolactam ring opening of the rhodamine groups are the main reason for the fluorescence enhancement responses of RB-KCC-1 and obtained a detection limit of 9.05 × 10-7. Based on the results obtained authors conclude that the synthesized materials are potential candidates for the detection and effective removal of Hg2+ in biological, environmental, and industrial fields[31]. The below figure indicates the Graphical representation of RB-Si Immobilized KCC-1 acted as a sensor for the detection of Hg+2 ions.

XV) Effect of pore structure of silica on CO oxidation activityJ. Xu et al. studied the CO oxidation reaction using different Ag supported on mesoporous supports such as MCM-41, SBA-15 and KCC-1. Authors observed that the morphology of the supports influence the dispersion of Ag nanoparticles, consequently shows difference in catalytic activity. It was mentioned that when KCC-1 was used, the migration and agglomeration of Ag particles can be effectively hindered by the open access mesopores. Authors therefore conclude that in comparison with SBA-15 and MCM-41, KCC-1 shows very high catalytic activity[8].

Ag/KCC-1Catalyst

2CO + O2 2CO2

XVI) Oxidation of organosilanes to silanolsM. Dhiman et al. reported ultrasmall and pseudo single atoms of gold supported on KCC-1 for the oxidation of organosilanes to silanols with high Turnover Number (TON), which is nearly half a million (591,000) for dimethylphenyl silane as a model substrate). The Extraordinary catalytic activity and stability in this study was attributed to dispersion of ultrasmall nanoparticles and pseudo-single atoms of Au as well as Auδ+ species on fibers of KCC-1. This oxidation was carried out only at 45°C using water as an oxidant and hydrogen was observed to be the by-product in this study. Authors also mention that, it was possible to easily separate Au based KCC-1 catalyst and they are stable for several cycles. These results clearly indicates the reusability of catalyst[32].

Si

R1

R2 H

R3

Si

R1

R2 OH

R3

ultra small Au nano particlessupported on /KCC-1

Silane Silanol

XVII) CO2 methanationHamid et al. studied the catalytic activity of KCC-1 for CO2 methanation and found that KCC-1 is a probable candidate for the examined reaction as compared to MCM-41. The high activity of KCC-1 was attributed to the presence of abundant oxygen vacancy facilitating the CO2 adsorption/dissociation. With the help of IR studies, it was also explained that KCC-1 has significantly higher basicity in addition to oxygen vacancy than that of MCM-41. These two properties of the catalysts were explained as reasons for improved catalytic performance of the catalyst. KCC-1 in this research work show good stability throughout 90 h of reaction due to the resistance towards Ostwald ripening[7]. Graphical representation of CO2 methanation using KCC-1 is presented below.

13

XVIII) n-Heptane isomerizationFatah et al. synthesized Molybdenum oxide (MoO3) supported KCC-1 and phosphorus (P) loaded on MoO3/KCC-1 (P/MoO3/KCC-1) and studied its activity for n-Heptane isomerization. Synthesis was carried out by mixing the MoO3 and KCC-1 powder in a ball mill equipment. For doing this, an agate container having 300 cm3 volume and six-piece of 20 mm diameter agate ball (weight of approximately 11 g each) were used. Authors found a slight change in the morphology after the addition of MoO3 and modification with H3PO4. It was also observed MoO3/KCC-1 shows excellent catalytic activity for n-heptane isomerization. This was attributed to the high amount and high accessibility of the active sites as well as the high dispersion of MoO3

[33]. Graphical representation of the process is presented below.

P/MoO3/KCC-1

n-Heptane Isomerized products of n-Heptane

XIX) Benzene hydroxylation and 1-hexene epoxidation reactionsYang et al. prepared nanosized monodispersed amphiphilic titanosilicate composite (TS-1@KCC-1) materials, which exhibited superior thermal stability as well as catalytic activity. These surface active titanosilicates were evaluated for their activity in benzene hydroxylation and 1-hexene epoxidation reactions. They observed that Rh(OH)3 species supported TS-1@KCC-1 exhibited higher catalytic activity in benzene hydroxylation with hydrogen peroxide under Pickering Interface Catalysis (PIC) in comparison with phase-boundary catalysis (PBC). The PIC reaction system in this study demonstrates excellent chemical stability and reasonable reusability.[34]

+ HO OH

OH

Phenol

Titano silicates composites(TS-KCC-1)

Hydrogen peroxide

XX) Synthesis of cycliccarbonate from carbon dioxide and epoxidesS.M. Sadeghzadeh also studied the KCC-1 supported heteropolyacid-based ionic liquid (KCC-1/IL/HPW) for the synthesis of cycliccarbonate from carbon dioxide and epoxides under mild conditions. Authors observed increase in catalytic efficiency of IL/HPW after immobilization onto KCC-1 NPs and KCC-1/IL/HPW NPs are found to be recovered from the reaction mixture during the work-up procedure. Also the recycled catalyst was reused for ten consecutive cycles and observed to be active without any significant loss in catalytic activity. The developed method of synthesis in this study indicate a green and low-cost protocol for making heteropolyacid-based catalysts and is also promising for developing similar type of materials[35].

O

R

+ CO2 O O

O

R

KCC-1/IL/HPW NPs

Epoxide CarbonDioxide Cyclic carbonate

XXI) Synthesis of tetrahydrodipyrazolo pyridinesUsing the developed heteropolyacid-based ionic liquid (KCC-1/IL/HPW) catalyst S.M. Sadeghzadeh also investigated the synthesis of tetrahydrodipyrazolo pyridines. Catalyst was found to be active for the studied reaction and also it was possible to recover and reuse it several times without any significant decrease in activity and selectivity. The high activity of the catalyst was attributed to high accessibility of active sites available with KCC-1 based catalyst[36].

14

O

O O+ 2 NH2NH2 +

R

OHC

+ NH4OAc

R

NH

NH

NN

NH

Fe3O4/KCC-1/IL/HPW MNP

1,3-dicarbonylcompounds Hydrazine

Aldehydederivatives

Ammoniumacetate Tetrahydrodipyrazolopyridines

XXII) Synthesis of high surface area Silicon carbides (SIC)Eunjin Jung et al. made an attempt to make high-surface area SiC spheres by the nano casting technology using a KCC-1 as a template. Polycarbosilane and poly(phenyl carbosilane) were used as the precursor for silicon carbide and it was possible to obtain hollow spheres by the inversion of a template structure. In this work, poly (phenyl carbosilane) worked as a binding agent due to its higher molecular weight. Fibrous strcture of KCC-1 was obtained for hollow spheres of silicon carbides. The resulting fibrous hollow spheres possessed SiC nano crystals and also shows 407 m2/g BET surface area[37]. Graphical representation of the process that describes the synthesis of high surface area Silicon carbides (SIC) is shown below.

XXIII) Synthesis of β-enaminonesZ. N. Siddiqui et al. developed an efficient protocol for the preparation of β-enaminones using KCC-1 sulphuric acid catalyst. Synthesis of KCC-1 sulfuric acid (KCC-1-SA) was carried out by dispersing KCC-1 (1.0 g) in CH2Cl2 (10 mL) in a flask. This was achieved by first dissolving chlorosulfonic acid (8 mmol) in CH2Cl2 (10 mL) and the resulting solution was added to the KCC-1 suspension through a constant-pressure dropping funnel under stirring for around 30 min at room temperature. After this addition, the resulting mixture was stirred for another 30 min at room temperature. The obtained brown solid was collected by filtration and it was washed with ether (50 mL). Procedure was concluded with a drying step at room temperature. Authors carried out the reactions under thermal solvent-free conditions and after a few minutes they obtained excellent yields. It was concluded that the amount of catalyst used is very low and the followed methodology that is environmentally benign in comparison with H2SO4, in terms of the amount, hazardous nature and reaction conditions. It was possible to recover the catalyst and is recyclable up to seven cycles without much loss in activity[38].

NH2

KCC-1 based sulphuric acid catalyst

R

Aniline Di-ketone

R - H, p-OMe, m-NO2, p-Cl, p-OH, p-CH3

OO+ NH

O

R

b-enaminone

15

NH2

KCC-1 based sulphuric acid catalyst

R

Aniline Di-ketone

R - H, p-OMe, m-NO2, m-NO2, p-Cl, p-OH, p-CH3

+

NHR

b-enaminone

OO

O

XXIV) Hydrogenolysis of Alkanes Fihri et al. studied Ru nanoparticle supported on KCC-1 for the hydrogenolysis of propane and ethane. It was observed from the TEM images that Ru nanopartciles are fully loaded on fibers of KCC-1. Authors proved that KCC-1 showed better catalytic performance as compared to conventional mesoporous silica materials such as MCM-41 and SBA-15. This examination was carried out by loading comparable Ru content on aforementioned supports and testing under identical conditions. It was also explained that the superior catalytic activity of KCC-1 based catalyst is attributed to high accessibility of Ru supported on KCC-1. In addition, high activity of Ru/KCC-1 catalyst was explained through HR-TEM studies. Authors mention that in case of Ru/KCC-1 hexagonal shaped nanoparticles were present having several corners and sharp edges and these possess reactive atoms with lowest coordination numbers. Catalyst based on KCC-1 was observed to be stable with excellent lifetime. Deactivation was not observed even after 8 days[3].

Ru/KCC-1

H2

+ CH4

Propane Ethane Methane

XXV) Cumene hydrocrackingM. L. Firmansyah et al. prepared ZSM-5 zeoilte with KCC-1 by combining a microemulsion technique with zeolite seed-assisted crystallization. The resulting material (FZSM-5) possessed very good physicochemical properties such as high surface area, fibrous morphology and strong acid sites. Authors explained that the cumene hydrocracking activity of the material could be attributed to the large number of active sites as well as their high accessibility. High dispersion of the metal particle was also observed, which was mainly due to the large surface area of the FZSM-5 type catalyst. The catalytic activity for cumene hydrocracking and EB dehydrogenation was enhanced by the protonation and introduction of Pt into the FZSM-5 type catalyst[39].

16

XXVI) Dehydrogenation of aqueous solutions of HCOOH/HCOONaS.M. Sadeghzadeh synthesized a novel PbS (lead sulphide) containing Ionic liquid IL-based KCC-1 catalysts (KCC-1/IL/PbS) and studied their catalytic applications in dehydrogenation of aqueous solutions of HCOOH/HCOONa to H2 and CO2 gas. It was found that the activity was due to dendritic fibrous morphology of the KCC-1 as well as the synergistic effect between KCC-1/IL and the small PbS NPs. Catalysts investigated in this study could be recovered and reused at least ten times with no decrease in activity[40].

HO OIonic liquid (IL)-based (KCC-1/IL/PbS)

Formic acid Carbon dioxide Hydrogen

H HO C O +

XXVII) Spidery catalyst for the synthesis of quinazoline-2,4(1H,3H)-dionesS.M. Sadeghzadeh synthesized multi-carboxylic hyperbranched polyglycerol groups (HPG) functionalized KCC-1 and nanocatalysts based on noble metal (Au, Pd, and Cu) were developed with the functionalized KCC-1. These resulting catalysts observed to be having ultrasmall size and monodisperse particles with uniform distribution, and high loading capacity. With the help of synthesized catalysts, an economically viable and green protocol was developed for reaction of CO2 with 2-aminobenzonitrile to obtain quinazoline-2,4(1H, 3H)-diones. Authors examined the impact of HPG by synthesizing catalyst with HPG functionalization and without HPG functionalization i.e KCC-1/HPG/X (X = Au, Pd, Cu) and KCC-1/X (X = Au, Pd, Cu). It was observed that the amount of motionless nanoparticles in KCC-1/HPG/X were about twice that in KCC-1/X. From the results, the effectiveness of HPG functionalization on KCC-1 was demonstrated[41].

CN

NH2

2-aminobenzonitrile

R

+ CO2

(KCC-1) based nanocatalyst(Au, Pd, and Cu)

HN

NH

O

Oquinazoline-2,4(1H, 3H)-dione

R

XXVIII) Production of 5 hydroxymethylfurfural (HMF)N. Chermahini et al. functionalized KCC-1 with propylsulfonic acid groups (Pr-SO3H) and investigated resulting catalysts efficiency for the production of 5 hydroxymethylfurfural (HMF) by the dehydration of fructose. Authors achieved 67.71% yield and 68.32% selectivity for the HMF at a 99.11% fructose conversion. Although the acid loading on the catalyst surface was low, the results observed in this study are better as compared to the reported studies. It was explained that the catalyst was reusable and can be synthesized by an environmentally friendly process for the heterogeneous catalytic manufacture of 5-HMF[42].

OO

HO

5-(Hydroxymethyl)furfural

O OH

OHHO

HO OH

(2S,3S,4R,5R)-2,5-bis(hydroxymethyl)tetrahydrofuran-2,3,4-triol

Propylsulfonic acidfunctionalized KCC-1

H H

H

17

XXIX) Ozonation of oxalic acidS. Afzala et al. investigated the Manganese incorporated fibrous silica nanosphere (MnOx-0.013/KCC-1) for ozonation of oxalic acid. Synthesized catalysts show excellent activity and stability with minimum Mn leaching in comparison to MnOx loaded on MCM-41. The high catalytic activity of studied catalysts was attributed to the generation of hydroxyl radical. Authors mentioned that surfacehydroxyl groups observed with the help of phosphates and ATR-FTIR were found to be active sites[43]. Graphical representation of Mn loaded KCC-1 used for ozonation of oxalic acid is shown below.

S.M. Sadeghzadeh studied gold (III) phosphorus complex containing HPG-based KCC-1 and tested its catalytic activity for the cyclization of propargylic amines with CO2 to provide 2-oxazolidinones. It was observed that hot filtration tests and selective catalyst poison examinations showed the presence of soluble Au species during the reaction process. However, recovery studies demonstrated that no significant decrease has occurred in the activity and metal content of recovered KCC-1/IL/Au. On the other hand catalysts were able to be recovered and reused at least ten times with no loss in activity and selectivity. Through the obtained results it was concluded that superior effectiveness of HPG@KCC-1/PPh2/Au nanocatalyst was attributed to isolated HPG units incorporated in the fibers of KCC-1, which could control the mechanistic aspects through preventing the formation of agglomerated gold (III) phosphorus complex and stabilization of active catalytic gold species[44].

O N

O

2-oxazolidinone

R3

R2R1

Fe3O4/KCC-1/tetrazolylidene/Aunanoparticles

R1

HNR3

R2

O C O

Propargylic amine derivatives

+

XXX) One-pot synthesis of benzamideHong-gen Peng et al. Synthesized a core–shell material consisting of KCC-1 and encapsulated TS-1 zeolite (Si/Ti=40) in a microemulsion system. Rh(OH)3 species were supported on KCC-1 and the resulting bifunctional Rh(OH)3/TS-1@KCC-1 catalyst was used for obtaining primary amides from aldehyde, NH3 and H2O2 through one-pot ammoximation and rearrangement(benzamide from benzaldehyde). Authors explained that Titanosilicates are potential candidates for catalyzing the oxidation of NH3 with H2O2 to yield the hydroxylamine intermediate. The formed intermediate again reacts with aldehydes or ketones via non-catalytic oximation to produce oximes. In this study, the Rh(OH)3 species are considered to be the catalytic sites for the rearrangement of aldehyde oximes to amides. The synthesized TS-1@KCC-1 catalyst was also found to have superior hydrothermal and mechanical stability and is a robust support for dispersing and stabilizing the Rh(OH)3 species[45].

CHO

Benzaldehyde

+ NH3 + H2O

CONH2Rh(OH)3 supported onTS-1/KCC-1

Benzamide

18

Catalog Products of KCC-1Different grades of KCC-1 products have been included in the catalogue and these products based on their varied properties can have different applications in catalysis, paints& coatings, cosmetics and drug delivery. Table.1 indicates the particle size, specific surface area and pore volume of different grades of KCC-1. Figure (1-6) show the Transition Electron Microscopy (TEM) images of KCC-1 product portfolio.

Category Grade Particle size (nm)

Spec.Surface Area (m2/g)

Pore Volume (cm3/g)

Large

KCC-1 L1 ~900-1000 ~ 700 ~1.40

KCC-1 L2 ~900-1000 ~ 600 ~1.20

KCC-1 L3 ~900-1000 ~ 550 ~0.80

MediumKCC-1 M1 ~400-450 ~ 400 ~0.50

KCC-1 M2 ~300-350 ~ 600 ~0.60

Small KCC-1 S1 ~ 130-190 ~380 ~ 0.80

Table.2: Summary of properties of KCC-1 product portfolio

Figure.1: Transition Electron Microscopy images of KCC-1 (L1 grade)

19

Figure.2: Transition Electron Microscopy images of KCC-1 (L2 grade)

Figure 3: Transition Electron Microscopy images of KCC-1 (L3 grade)

20

Figure 4: Transition Electron Microscopy images of KCC-1 (M1 grade)

Figure 5: Transition Electron Microscopy images of KCC-1 (M2 grade)

21

Figure 6: Transition Electron Microscopy images of KCC-1 (S1 grade)

References:

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Bhunia, Sigismund Melissen, Manas R. Parida, Pradip Sarawade,┴ Jean-Marie Basset, Dalaver H. Anjum, Omar F. Mohammed, Philippe Sautet, Tangui Le Bahers, and Kazuhiro Takanabe. Chemistry of Materials 2015 (27) 8237−824717. Ultrasmall nanoparticles and pseudo-single atoms of platinum supported on fibrous nanosilica (KCC-1/Pt): engineering selectivity of hydrogenation reactions. Mahak Dhiman and Vivek Polshettiwar, Journal of Materials Chemistry A, 2016 (4)1241618. Fibrous nano-silica supported palladium nanoparticles: An efficient catalyst for the reduction of 4-nitrophenol and hydrodechlorination of 4-chlorophenol under mild conditions. Xuanduong Le, Zhengping Dong , Xinlin Li , Wei Zhang , Minhdong Le , Jiantai Ma, Catalysis Communications 59 (2015) 21–2519. Palladium nanoparticles immobilized on core–shell magnetic fibers as a highly efficient and recyclable heterogeneous catalyst for the reduction of 4-nitrophenol and Suzuki coupling reactions. Xuanduong Le,a Zhengping Dong, Yansheng Liu, Zhicheng Jin,aThanh-Do Huy, Minhdong Le and Jiantai Ma. Journal of Material Chemistry A 2014( 2) 19696–1970620. Efficient Synthesis of Monodisperse Metal (Rh, Ru, Pd) Nanoparticles Supported on Fibrous Nanosilica (KCC-1) for Catalysis. Mahak Dhiman, Bhagyashree Chalke, and Vivek Polshettiwar. ACS Sustainable Chemical Engineering. 2015 (3)3224−323021. Fibrous nano-silica containing immobilized Ni@Au core–shellnanoparticles: A highly active and reusable catalyst for thereduction of 4-nitrophenol and 2-nitroaniline. Xuanduong Le, Zhengping Dong, Wei Zhang, Xinlin Li, Jiantai Ma. Journal of Molecular Catalysis A: Chemical 395 (2014) 58–6522. Fibrous Nano-Silica (KCC-1)-Supported Palladium Catalyst: Suzuki Coupling Reactions Under Sustainable Conditions. Aziz Fihri, Dongkyu Cha, Mohamed Bouhrara, Noor Almana, and Vivek Polshettiwar. ChemSusChem 2012 (5) 85–8923. KCC-1 supported palladium nanoparticles as an efficient and sustainable nano catalyst for carbonylative Suzuki–Miyaura cross-coupling, Prashant Gautam, Mahak Dhiman, Vivek Polshettiwar and Bhalchandra M. Bhanage, Green Chem., 2016 (18)589024. Ionic liquid immobilized onto fibrous nano-silica: A highly active and reusable catalyst for the synthesis of quinazoline-2,4(1 H,3 H)-diones, Seyed Mohsen Sadeghzadeh, Catalysis Communications 72 (2015) 91–9625. Bis(4-pyridylamino)triazine-stabilized magnetite KCC-1: a chemoselective, efficient, green and reusable nanocatalyst for the synthesis of N-substituted 1,4-dihydropyridines. Seyed Mohsen Sadeghzadeh. RSC Advances 2016 (6) 9958626. Palladium Nanoparticles Supported on Fibrous Silica (KCC-1-PEI/Pd): A Sustainable Nanocatalyst for Decarbonylation Reactions. Pintu K. Kundu, Mahak Dhiman, Atanu Modak, Arindam Chowdhury, Vivek Polshettiwar, and Debabrata Maiti. ChemPlusChem 2016(81)1142 – 114627. Pd/APTPOSS@KCC-1 as a new and efficient support catalyst for C–H activation. Seyed Mohsen Sadeghzadeh, Rahele Zhiani and Shokufe Emrani. RSC Adv., 2017, 7, 2488528. Silicon oxynitrides of KCC-1, SBA-15 and MCM-41 for CO2 capture with excellent stability and regenerability. Umesh Patil, Aziz Fihri, Abdul-Hamid Emwas and Vivek Polshettiwar. Chemical Science 2012 (3) 222429. Immobilization of lipase on mesoporous silica nanoparticles with hierarchical fibrous pore. Zafar Ali, Lei Tian, Panpan Zhao, Baoliang Zhang, Nisar Ali, Muhammad Khan,Qiuyu Zhang. Journal of Molecular Catalysis B: Enzymatic 134 (2016) 129–135 30. Nanostructured Silica-Titania Hybrid using Fibrous Nanosilica as Photocatalysts. Nisha Bayal, Rustam Singh, and Vivek Polshettiwar. DOI: 10.1002/cssc.20170013531. Multifunctional fibrous silica composite with high optical sensing performance and effective removal ability toward Hg2+ ions. Zebin Sun, Dan Guo, Li Zhang, Haizhen Li, Bo Yang and Shiqiang Yan, Journal of Materials Chemistry B, 2015 (3)3201-321032. Organosilane Oxidation with a Half Million Turnover Number using Fibrous Nanosilica Supported Ultrasmall Nanoparticles and Pseudo-Single Atoms of Gold. Mahak Dhiman, Bhagyashree Chalke, and Vivek Polshettiwar. J. Mater. Chem. A, 2017, DOI: 10.1039/C6TA09434A33. n-Heptane isomerization over molybdenum supported on bicontinuous concentric lamellar silica KCC1: Influence of phosphorus and optimization using response surface methodology (RSM). N.A.A. Fataha S. Triwahyonob, A.A. Jalila , N. Salamun, C.R. Mamat, Z.A. Majid. http://dx.doi.org/10.1016/j.cej.2016.12.02834. Amphiphilic Titano silicates as Pickering Interfacial Catalysts for Liquid-Phase Oxidation Reactions. Yulin Yang, Wen-Juan Zhou, Armin Liebens, Jean-Marc Clacens, Marc Pera-Titus, and Peng Wu. Journal of physical chemistry 2015 (119) 25377−25384

References (continued):

23

35. A heteropolyacid-based ionic liquid immobilized onto fibrous nano-silica as an efficient catalyst for the synthesis of cyclic carbonate from carbon dioxide and epoxides, Seyed Mohsen Sadeghzadeh, Green Chemistry, 2015(17) 3059–306636. A heteropolyacid-based ionic liquid immobilized onto magnetic fibrous nano-silica as robust and recyclable heterogeneous catalysts for the synthesis of tetrahydrodipyrazolopyridines in water. Seyed Mohsen Sadeghzadeh, RSC Advances 2016 (6)7597337. The Synthesis of High-Surface Area Silicon Carbide by Conversion Method Using Carbosilane Polymer. Eunjin Jung, Yoon Joo Lee, Woo Teck Kwon, Younghee Kim, Dong Geun Shin, and Soo Ryong Kim. Defect and Diffusion Forum 353 (2014) 244-24738. Nano Fibrous Silica Sulphuric Acid as an Efficient Catalyst for the Synthesis of β-Enaminone. Zeba N. Siddiqui, Kulsum Khan, Nayeem Ahmed. Catalysis Letters 2014 (144)623–63239. Synthesis and characterization of fibrous silica ZSM-5 for cumene hydrocracking, M. L. Firmansyah, A. A. Jalil, S. Triwahyono, H. Hamdan, M. M. Salleh, W. F. W. Ahmadd, G. T. M. Kadj, Catalysis Science & Technology, 2016, 6, 5178–518240. PbS based ionic liquid immobilized onto fibrous nano-silica as robust and recyclable heterogeneous catalysts for the hydrogen production by dehydrogenation of formic acid, Microporous and Mesoporous Materials 234 (2016) 310-31641. Spidery catalyst for the synthesis of quinazoline- 2,4IJ1H,3H)-diones, Seyed Mohsen Sadeghzadeh, Catalysis Science & Technology, 2016, 6, 1435–1441-143542. Production of 5-hydroxymethylfurfural from fructose using a spherically fibrous KCC-1 silica Catalyst, Alireza Najafi Chermahini, Fereshte Shahangi, Hossein A. Dabbagh Mohammad Saraji, RSC Advances, 2016, 6, 3380443. Synthesis of manganese incorporated hierarchical mesoporous silicananosphere with fibrous morphology by facile one-pot approach forefficient catalytic ozonation. Shahzad Afzal, Xie Quana, Shuo Chen, Jing Wang, Dost Muhammad, Journal of Hazardous Materials 318 (2016) 308–31844. A green approach for the synthesis of 2- oxazolidinones using gold(I) complex immobilized on KCC-1 as nanocatalyst at room temperature. Seyed Mohsen Sadeghzadeh. Applied Organo metalic Chemistry 2016(30) 835–84245. One-pot synthesis of benzamide over a robust tandem catalyst based on center radially fibrous silica encapsulated TS-1. Hong-gen Peng, Le Xu, Haihong Wu, Kun Zhang and Peng Wu. Chemical Communications., 2013 (49) 2709-2711

References (continued):

High Surface Area Silica Nanoparticles

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SILICON (Compounds)SILICON (Compounds)

14-610014-6100

a

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~700 m2/g, (KCC-1 L1) (112945-52-5) SiO2; FW: 60.09; white pwdr.; SA: ~700 m2/g; P.Vol. ~1.4 cm3/g Note: Diameter: ~900-1000nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. Novel fibrous shaped silica nanospheres, denoted as KCC-1 (KAUST Catalysis Center)[1], have unique

physical properties which have never before been reported in silica materials. These nanomaterials have been developed by Prof. J. M. Basset of King Abdullah University of Science and Technology (KAUST). A fibrous surface morphology arranged in three-dimensional structure forms the spheres (Fig. 1). Unlike traditional pore-based silica, these nanospheres possess a fibrous structure that increases accessibility to the available surface area; this in turn, significantly increases the catalytic activity.

These materials exhibit excellent physical properties, including a high surface area, a fibrous surface morphology, good thermal and hydrothermal stabilities and high mechanical stability (Table 1). The fibrous morphology of KCC-1 remains unaffected even after mechanical compression up to 216 MPa pressure. This is superior to the conventional MCM-41 type of silica, which is affected at pressure 86 MPa.[1]

A range of heterogeneous catalysts, prepared using KCC-1 as a supporting material, have been showing excellent catalytic activity for various transformations of research and industrial importance. As a catalyst support, sorbent or carrier, KCC-1 is able to demonstrate superior activity as compared to regular mesoporous silica materials in energy related processes[2-3], a variety of organic reactions[4-7], biomedical applications and drug delivery systems[8], optoelectronic devices[9] and many others.

Product # Category Grade Particle Size (nm) Surface Area (m2/g) Pore Volume (cm3/g)

14-6100 Large (KCC-1 L1) ~900-1000 ~700 ~1.4

14-6110 Large (KCC-1 L2) ~900-1000 ~600 ~1.2

14-6120 Large (KCC-1 L3) ~900-1000 ~550 ~0.9

14-6200 Medium (KCC-1 M1) ~400-450 ~400 ~0.7

14-6210 Medium (KCC-1 M2) ~300-350 ~600 ~0.6

14-6300 Small (KCC-1 S1) ~130-190 ~380 ~0.8

References:1. Angew. Chem. Int. Ed. 2010, 49, 96522. Chem. Mater. 2015, 27, 82373. ACS Catalysis. 2016, 6, 27704. ChemSusChem 2012, 5, 855. Green Chem., 2016, 18, 5890 6. Angew. Chem. Int. Ed. 2011, 50, 27477. RSC Adv., 2017, 7, 248858. Langmuir 2014, 30, 108869. J. Mater. Chem. B, 2015, 3, 3201

High Surface Area Silica Nanoparticles

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SILICON (Compounds)14-611014-6110

a

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~600 m2/g, (KCC-1 L2) (112945-52-5) SiO2; FW: 60.09; white pwdr.; SA: ~600 m2/g; P.Vol. ~1.20 cm3/g Note: Diameter: ~900-1000nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g5g

Technical Note:1. See 14-6100 (page 24)

14-612014-6120

a

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~550 m2/g (KCC-1 L3) (112945-52-5) SiO2; FW: 60.09; white pwdr.; SA: ~550 m2/g; P.Vol. ~0.97 cm3/g Note: Diameter: ~900-1000nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g5g

Technical Note:1. See 14-6100 (page 24)

14-620014-6200

a

High Surface area Silica nanoparticles, medium, particle size ~400-450 nm, surface area ~400 m2/g, (KCC-1 M1) (112945-52-5) SiO2; FW: 60.09; white pwdr.; SA: ~400 m2/g; P.Vol. ~0.7 cm3/g Note: Diameter: ~400-450nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g5g

Technical Note:1. See 14-6100 (page 24)

14-621014-6210

a

High Surface area Silica nanoparticles, medium, particle size ~300-350 nm, surface area ~600 m2/g, (KCC-1 M2) (112945-52-5) SiO2; FW: 60.09; white pwdr.; SA: ~600 m2/g; P.Vol. ~0.6 cm3/g Note: Diameter: ~300-350nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g5g

Technical Note:1. See 14-6100 (page 24)

14-630014-6300

a

High Surface area Silica nanoparticles, small, particle size ~130-190 nm, surface area ~380 m2/g, (KCC-1 S1) (112945-52-5) SiO2; FW: 60.09; white to beige pwdr.; SA: ~380 m2/g; P.Vol. ~0.8 cm3/g Note: Diameter: ~130-190nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g5g

Technical Note:1. See 14-6100 (page 24)

14-631014-6300

a

High Surface area Silica nanoparticles, small, particle size ~40-50 nm, surface area ~520 m2/g, (KCC-1 S2) (112945-52-5) SiO2; FW: 60.09; white to beige pwdr.; SA: ~520 m2/g; P.Vol. ~1.3 cm3/g Note: Diameter: ~40-50nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g5g

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ALUMINUM (Compounds)ALUMINUM (Compounds)

13-030013-0300

a

Aluminum hydroxide isophthalate MOF (CAU-10, Isophthalate:Al=0.9-1.0) (1416330‑84‑1) Al(OH)(C8H4O4)x, X = 0.9-1.0; white solid; SA: 620-640 m2/g ; P.Vol. 0.23-0.27 cm3/g Note: Particle size: 0.4-0.7 micron, Thermal stability: 400ºC, Activation temperature: 150ºC Sold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

500mg2g

Technical Note:1. MOF exhibits water adsorption characteristics which make it a promising adsorbent for application in

heat-exchange processes1

References:1. Water adsorption behaviour of CAU‑10‑H: a thorough investigation of its structure–property relationships,

J. Mater. Chem. A, 2016, 4, 11859.2. Structures, Sorption Characteristics, and Nonlinear Optical Properties of a New Series of Highly Stable

Aluminum MOFs., Chem. Mater. 2013, 25, 17−26.

BIOCATALYSTS (Compounds) 07-315507-3155

a

CalB immo 1090™ - Immobilized enzyme white to slightly yellow spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 300-710 micron; CalB immo 1090 is an adsorbed preparation and is suitable for applications in solvent-free systems like oils, as well as organic solvents and it and can be used for (regio- and stereoselective) esterifications and transesterifications. CalB Immo 1090 has many advantages including high activity and the possibility to use in oils, organic solvent and bi-phasic systems. Sold in collaboration with Purolite for research purposes only.

10g50g

250g

07-315207-3152

a

CalB immo 5587™ - Immobilized enzyme white to slightly yellow spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 300-710 micron; CalB immo 5587 is an adsorbed preparation and is particularly suitable for applications where cost is an essential parameter, like biodiesel or industrial oil manufacture. CalB Immo 5587 has many advantages including cost-effectiveness in processes like biodiesel manufacture. It is also a highly robust carrier, particularly suitable for column configurations. Sold in collaboration with Purolite for research purposes only.

10g50g

250g

07-315907-3159

a

CalB immo 5872™ - Immobilized enzyme white to slightly yellow spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 300-1500 micron;CalB immo 5872 is an adsorbed preparation and is suitable for applications in solvent-free systems like oils, as well as organic solvents and it and can be used for (regio- and stereoselective) esterifications and transesterifications. CalB Immo 5872 has many advantages including cost-effectiveness and the possibility to use in oils, organic solvent and bi-phasic systems. Sold in collaboration with Purolite for research purposes only.

10g50g

250g

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BIOCATALYSTS (Compounds)07-314207-3142

a

CalB immo 8285™ - Immobilized enzyme white to slightly yellow spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 100-710 micron; CalB immo 8285 is covalently immobilized and is suitable for applications in water, organic solvents as well as solvent-free systems and can be used for (regio- and stereoselective) hydrolysis, esterifications and transesterifications. The lipase is immobilized by covalent immobilization onto Purolites highly hydrophobic carrier Purolite ECR8285 (an epoxy/butyl methacrylate co-polymer). Sold in collaboration with Purolite for research purposes only.

10g 50g 250g

07-314807-3148

a

CalB immo 8806™ - Immobilized enzyme white to slightly yellow spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 300-710 micron; CalB immo 8806 is an adsorbed preparation and is suitable for applications in solvent-free systems like oils, as well as organic solvents and it and can be used for (regio- and stereoselective) esterifications and transesterifications. CalB Immo 8806 has many advantages including high activity and the possibility to use in oils, organic solvent and bi-phasic systems. Sold in collaboration with Purolite for research purposes only.

10g 50g 250g

96-4050 CalB immo KIT™ - Immobilized enzyme

See page 107 07-313007-3130

a

CalB immo Plus™ - Immobilized enzyme white to off white spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 300-710 micron; CalB immo Plus is suitable for applications in organic solvents as well as solvent-free systems and can be used for (regio- and stereoselective) esterifications and transesterifications. CalB Immo Plus has many advantages including high activity and high mechanical stability. Sold in collaboration with Purolite for research purposes only.

10g 50g 250g

07-313307-3133

a

CalB immo Plus Food Grade™ - Immobilized enzyme white to slightly yellow spherical beads, dry (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Particle Size: 300-710 micron; CalBimmo Plus Food Grade is supplied in food-grade quality and conforms to the General Specifications and Considerations for Enzyme Preparations Used in Food Processing of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). CalB immo Plus is suitable for applications in organic solvents as well as a solvent-free systems and can be used for (regio- and stereoselective) esterifications and transesterifications. CalB Immo Plus has many advantages including high activity and high mechanical stability. Sold in collaboration with Purolite for research purposes only.

10g 50g 250g

06-092506-0925

a

Enzyme carrier Lifetech™ ECR1030M White to off white spherical beads (wet); SA: 80 - 120 m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 220-340 Å; Lifetech ECR1030M is a copolymer of divinylbenzene (DVB) and methacrylate with no functional groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase immobilization such as CALB. Lifetech ECR1030M main features are high mechanical stability compared to other existing resins, low surface area that grants high enzyme activity at low protein loading. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

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BIOCATALYSTS (Compounds)07-221507-2215

a

Enzyme carrier Lifetech™ ECR1504 White to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Lifetech ECR1504 is a copolymer of divinylbenzene (DVB) and styrene functionalized with tertiary amines. It is used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the tertiary amines on the polymer. It is particularly suitable for immobilization of enzymes with iP in the range 3 - 5 like many glycosidaseses. Lifetech ECR1504 main features are possibility to regenerate the resin, pH adjustment before immobilization and large particle size for column applications. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

07-222007-2220

a

Enzyme carrier Lifetech™ ECR1508 White to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Lifetech ECR1508 is copolymer of divinylbenzene (DVB) and styrene functionalized with tertiary amines. It is used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the tertiary amines on the polymer. It is particularly suitable for immobilization of enzymes with iP in the range 3 - 5 like many glycosidaseses. Lifetech ECR1508 main features are possibility to regenerate the resin, pH adjustment before immobilization and large particle size for column applications. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

07-222407-2224

a

Enzyme carrier Lifetech™ ECR1604 White to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Lifetech ECR1604 is a copolymer of divinylbenzene (DVB) and styrene functionalized with quaternary amines. It is used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the tertiary amines on the polymer. It is particularly suitable for immobilization of enzymes with iP in the range 3 - 5 like many glycosidaseses. Lifetech ECR1604 main features are possibility to regenerate the resin, pH adjustment before immobilization and large particle size for column applications. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

07-223007-2230

a

Enzyme carrier Lifetech™ ECR1640 White to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Lifetech ECR1640 is a copolymer of divinylbenzene (DVB) and styrene functionalized with quaternary amines. It is used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the tertiary amines on the polymer. It is particularly suitable for immobilization of enzymes with iP in the range 3 - 5 like many glycosidaseses. Lifetech ECR1640 main features are possibility to regenerate the resin, pH adjustment before immobilization and large particle size for column applications. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-092806-0928

a

Enzyme carrier Lifetech™ ECR1061M White to off white spherical beads (wet); SA: 400 - 510 m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 600-750 Å; Lifetech ECR1061M is a copolymer of divinylbenzene (DVB) with methacrylate with no functional groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase immobilization as CALB. Lifetech ECR1061M main features are higher porosity compared to Lifetech ECR1030M to allow better diffusion for bulky substrates or better application in viscous systems. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

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BIOCATALYSTS (Compounds)06-090506-0905

a

Enzyme carrier Lifetech™ ECR1090F White to off white spherical beads (wet); SA: 750 - 850 m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 150-300 micron; Pore Diameter: 900-1100 Å; Lifetech ECR1090F is a copolymer of divinylbenzene (DVB) and styrene with high porosity and no functional groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase immobilization. Lifetech ECR1090F main features are high porosity, high mechanical stability and high surface area. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-091306-0913

a

Enzyme carrier Lifetech™ ECR1090M White to off white spherical beads (wet); SA: 750 - 850 m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 900-1100 Å; Lifetech ECR1090M is a copolymer of divinylbenzene (DVB) and styrene with high porosity and no functional groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase immobilization. Lifetech ECR1090M main features are high porosity, high mechanical stability and high surface area. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-092206-0922

a

Enzyme carrier Lifetech™ ECR1091M White to off white spherical beads (wet); SA: > 450 m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 950-1200 Å; Lifetech ECR1091M is a copolymer of divinylbenzene (DVB) and styrene with very high porosity and no functional groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase immobilization. Lifetech ECR1091M main features are high porosity, high mechanical stability and high surface area. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-081006-0810

a

Enzyme carrier Lifetech™ ECR8204F White to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf life: 6 months; Particle Size: 150-300 micron; Pore Diameter: 300-600 Å; Lifetech ECR8204F is a methacrylate polymer functionalized with epoxy groups, used for covalent enzyme immobilization. Epoxides form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8204F main features are the low porosity, the hydrophilicity, high mechanical strengh and it is optimal for use in batch reactors. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-081306-0813

a

Enzyme carrier Lifetech™ ECR8204M White to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 6 months; Particle size: 300-710 micron; Pore Diameter: 300-600 Å; Lifetech ECR8204M is a methacrylate polymer functionalized with epoxy groups, used for covalent enzyme immobilization. Epoxides form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8204M main features are the low porosity, the hydrophilicity, high mechanical strengh and it is optimal for use in batch reactors and columns.

50g5x50g

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BIOCATALYSTS (Compounds)06-081706-0817

a

Enzyme carrier Lifetech™ ECR8209F white to off white spherical beads (wet) (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 6 months; Particle Size: 150-300 micron; Pore Diameter: 300-600 Å; Lifetech ECR8209F is a methacrylate polymer functionalized with epoxy groups, used for covalent enzyme immobilization. Epoxy groups form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8209F main features are the high porosity, the hydrophilicity and it is optimal for use in batch reactors.

50g5x50g

07-151207-1512

a

Enzyme carrier Lifetech™ ECR8309F white to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 150-300 micron; Pore Diameter: 600-1200 Å; Lifetech ECR8309F is a methacrylate polymer functionalized with amino groups on a short spacer (C2). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8309F main features are the medium porosity, the hydrophilicity and its optimal use in batch reactors. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

07-151507-1515

a

Enzyme carrier Lifetech™ ECR8309M White to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 600-1200 Å; Lifetech ECR8309M is a methacrylate polymer functionalized with amino groups on a short spacer (C2). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8309M main features are the medium porosity, the hydrophilicity and its optimal use in batch reactors and columns. Sold in collaboration with Purolite for research purposes only.

50g5x50g

07-151807-1518

a

Enzyme carrier Lifetech™ ECR8315F white to off white spherical beads (wet); SA: 60 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 150-300 micron; Pore Diameter: 1200-1800 Å; Lifetech ECR8315F is a methacrylate polymer functionalized with amino groups on a short spacer (C2). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. Lifetech ECR8315F main features are the high porosity, the hydrophilicity and its optimal use in batch reactors. Sold in collaboration with Purolite for research purposes only.

50g250g

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BIOCATALYSTS (Compounds)07-152007-1520

a

Enzyme carrier Lifetech™ ECR8315M white to off white spherical beads (wet); SA: 60 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 1200-1800 Å; Lifetech ECR8315M is a methacrylate polymer functionalized with amino groups on a short spacer (C2). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8315M main features are the medium porosity, the hydrophilicity and its optimal use in batch reactors and columns. Sold in collaboration with Purolite for research purposes only.

50g250g

07-152307-1523

a

Enzyme carrier Lifetech™ ECR8409F white to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 150-300 micron; Pore Diameter: 600-1200 Å; Lifetech ECR8409F is a methacrylate polymer functionalized with amino groups on a long spacer (C6). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8409F main features are the medium porosity, the hydrophilicity and its optimal use in batch reactors. Sold in collaboration with Purolite for research purposes only.

50g250g

07-152507-1525

a

Enzyme carrier Lifetech™ ECR8409M white to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 600-1200 Å; Lifetech ECR8409M is a methacrylate polymer functionalized with amino groups on a long spacer (C6). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8409M main features are the medium porosity, the hydrophilicity and its optimal use in batch reactors and columns. Sold in collaboration with Purolite for research purposes only.

50g250g

07-152807-1528

a

Enzyme carrier Lifetech™ ECR8415F white to off white spherical beads (wet); SA: 60 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 150-300 micron; Pore Diameter: 1200-1800 Å; Lifetech ECR8415F is a methacrylate polymer functionalized with amino groups on a long spacer (C6). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8415F main features are the high porosity, the hydrophilicity and its optimal use in batch reactors. Sold in collaboration with Purolite for research purposes only.

50g250g

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BIOCATALYSTS (Compounds)07-153007-1530

a

Enzyme carrier Lifetech™ ECR8415M White to off white spherical beads (wet); SA: 60 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 1200-1800 Å; Lifetech ECR8415M is a methacrylate polymer functionalized with amino groups on a long spacer (C6). It is used for covalent enzyme immobilization by pre-activation of the resin with glutaraldehyde and to subsequently form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature, at low ionic buffer strength. It can also be used for enzyme immobilization by ionic interaction of the ionizable surface aminoacids (Lys, Arg, His, Asp, Glu) with the charged amines on the polymer. Lifetech ECR8415M main features are the high porosity, the hydrophilicity and its optimal use in batch reactors. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

07-153207-1532

a

Enzyme carrier Lifetech™ ECR8806F White to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 150-300 micron; Pore Diameter: 350-600 Å; Lifetech ECR8806F is a methacrylic polymer functionalized with octadecyl groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase and transaminases immobilization. Lifetech ECR8806F main features are very enzyme activity achieved upon immobilization compared to other existing resins. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

07-153507-1535

a

Enzyme carrier Lifetech™ ECR8806M White to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-710 micron; Pore Diameter: 350-600 Å; Lifetech ECR8806M is a methacrylic polymer functionalized with octadecyl groups. It is used for enzyme immobilization by adsorption (hydrophobic interaction) and it is particularly suitable for lipase and transaminases immobilization. Lifetech ECR8806M main features are very high enzyme activity achieved upon immobilization compared to other existing resins. Optimal for column packed reactors. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-082006-0820

a

Enzyme carrier Lifetech™ ECR8209M white to off white spherical beads (wet); SA: 70 min. m2/g (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 6 months; Particle Size: 300-710 micron; Pore Diameter: 600-1200 Å; Lifetech ECR8209M is a methacrylate polymer functionalized with epoxy groups, used for covalent enzyme immobilization. Epoxy groups form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8209M main features are the high porosity, the hydrophilicity and it is optimal use in batch reactors and columns.

50g5x50g

06-082306-0823

a

Enzyme carrier Lifetech™ ECR8215F white to off white spherical beads (wet); SA: 60 min. m2/g (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 6 months; Particle Size: 150-300 micron; Pore Diameter: 1200-1800 Å; Lifetech ECR8215F is a methacrylate polymer functionalized with epoxy groups, used for covalent enzyme immobilization. Epoxy groups form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8215F main features are the very high porosity, the hydrophilicity and it is optimal for use in batch reactors.

50g 5x50g

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BIOCATALYSTS (Compounds)06-082606-0826

a

Enzyme carrier Lifetech™ ECR8215M white to off white spherical beads (wet); SA: 60 min. m2/g (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 6 months; Particle Size: 300-710 micron; Pore Diameter: 1200-1800 Å; Lifetech ECR8215M is a methacrylate polymer functionalized with epoxy groups, used for covalent enzyme immobilization. Epoxy groups form very stable covalent linkages with different protein surface groups as ε-NH2 in Lys or nucleophiles (amino, thiol, phenolic). Immobilization is performed under very mild experimental conditions of pH and temperature, at high ionic buffer strength. Lifetech ECR8215M main features are the very high porosity, the hydrophilicity and its optimal use in batch reactors and columns.

50g5x50g

06-082806-0828

a

Enzyme carrier Lifetech™ ECR8285 white to off white spherical beads (wet); SA: 100-200 m2/g (store cold) Note: Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 6 months; Particle Size: 250-1000 micron; Pore Diameter: 400-600 Å; Lifetech ECR8285 is a methacrylate polymer functionalized with both butyl and epoxy groups. This combination creates a good balance of hydrophobicity that makes the polymer optimal for immobilization of hydrophobic enzymes like lipases and transaminases. Epoxides form very stable covalent linkages with different protein groups (amino, thiol, phenolic) under very mild experimental conditions of pH and temperature. Lifetech ECR8285 main features are the process advtantages deriving from hydrophobic property combined with epoxy groups allowing the use in bi-phasic systems. Sold in collaboration with Purolite for research purposes only.

50g5x50g

96-0255 Enzyme carrier Lifetech™ ECRKIT1

See page 107 96-4065 Lipase immo Kit - Immobilized enzymes

See page 109

CALCIUM (Compounds) 20-820020-8200

a

Bis(N,N’-diisopropylformamidinato)calcium(II) dimer, (99.99 %-Ca) PURATREM (1959584‑78‑1) C28H60Ca2N8; FW: 588.99; tan to light-brown pwdr. air sensitive, moisture sensitive Note: Product sold under, use subject to, terms and conditions of label license at www.strem.com/harvard2.

1g5g

Technical Note:1. Calcium amidinate precursor for the atomic layer deposition (ALD) of

calcium containing thin films.References:

1. Sang Bok Kim, Chuanxi Yang, Tamara Powers, Luke M. Davis, Xiabing Lou, and Roy G. Gordon, Angew. Chem. Int. Ed., 2016, 55, 10228 –10233.

CARBON (Elemental Forms) 06-253006-2530

a

Graphene oxide (4mg/ml water dispersion) - low Mn. (1034343‑98‑0) C; brown liq. Note: Diameter: 5-30 micron flakes;

100ml 500ml

06-0330 Graphene Quantum Dots (GQDs), Aqua-Green Luminescent (1034343‑98‑0)

See page 48 06-0332 Graphene Quantum Dots (GQDs) in water, Aqua-Green Luminescent (1034343‑98‑0)

See page 48 06-0334 Graphene Quantum Dots (GQDs), Blue Luminescent (1034343‑98‑0)

See page 49 06-0336 Graphene Quantum Dots (GQDs) in water, Blue Luminescent (1034343‑98‑0)

See page 49 06-0340 Graphene Quantum Dots (GQDs) in water, Cyan Luminescent (1034343‑98‑0)

See page 49

N N

H

iPr iPr

Ca

N N

HiPr iPr

CaN

NH

iPr

iPr

N

NH

iPr

iPr

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CARBON (Elemental Forms)06-036506-0365

a

High Strength Metallurgical Graphene on GLASS HSMG® (10x10mm) (1034343‑98‑0) C; FW: 12.011Note: HSMG® Sold under license for research purposes only. U.S. Patent no. 9,284,640 B2.

1pc

06-034506-0345

a

High Strength Metallurgical Graphene on PMMA HSMG® (10x10mm) (1034343‑98‑0) C; FW: 12.011Note: HSMG® Sold under license for research purposes only. U.S. Patent no. 9,284,640 B2.

1pc

06-035506-0355

a

High Strength Metallurgical Graphene on PMMA HSMG® (25x25mm) (1034343‑98‑0) C; FW: 12.011Note: HSMG® Sold under license for research purposes only. U.S. Patent no. 9,284,640 B2.

1pc

06-036006-0360

a

High Strength Metallurgical Graphene on PMMA HSMG® (50x50mm) (1034343‑98‑0) C; FW: 12.011Note: HSMG® Sold under license for research purposes only. U.S. Patent no. 9,284,640 B2.

1pc

CHROMIUM (Compounds) 24-000024-0000

a

Chromium(III) acetate, 97% (1066‑30‑4) Cr(CH3CO2)3; FW: 229.13; green pwdr.

100g 500g

24-242724-2427

aHAZ

Chromium (III) naphthenate, 30-40% in heavy naphtha (2-2.5% Cr) (61788‑69‑0) green liq.

100g 500g

COBALT (Compounds) 27-102527-1025

a

Bis(1,4-di-t-butyl-1,3-diazabutadienyl)cobalt(II) Co(DAD)2, min. 98% (99.999%-Co) PURATREM (177099‑51‑3) C20H40CoN4; FW: 395.49; dark green-blue xtl. air sensitive Note: U.S. Patent Application No. 13/818,154. Product sold under, use subject to, terms and conditions of label license at www.strem.com/waynestate1

N

Co

N

N

N

tButBu

tBu tBu

250mg 1g 5g

27-048627-0486

aampHAZ

Bis(N,N’-di-i-propylacetamidinato)cobalt(II), min. 98% (99.99%-Co) PURATREM (Co(iPr-MeAMD)2 (635680‑58‑9) C16H34CoN4; FW: 341.40; green xtl. air sensitive, moisture sensitive Note: Product sold under, use subject to, terms and conditions of label license at www.strem.com/harvard2.

NCo

N N

N

iPr

iPr

iPr

MeMe

iPr 250mg 1g 5g

27-401027-4010

a

lambda-Tris[(1S,2S)-1,2-diphenyl-1,2-ethane-diamine]cobalt(III) chloride tetrakis[3,5-bis(tri-fluoromethyl)phenyl]borate dihydrate SKJ-1 (1542135‑29‑4) C74H60BCl2CoF24N6; FW: 1629.92(1665.92); orange pwdr. Note: U.S. Patent 14/417655

50mg 250mg

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COBALT (Compounds)27-401127-4011

a

delta-Tris[(1S,2S)-1,2-diphenyl-1,2-ethane-diamine]cobalt(III) chloride tetrakis(2, 3, 4, 5, 6- pentafluorophenyl)borate trihydrate SKJ-3 (1867120‑15‑7) C66H48BCl2CoF20N6; FW: 1445.74 (1501.80); orange solid Note: U.S. Patent 14/417655

50mg 250mg

COPPER (Compounds) 29-022529-0225

a

Copper(I) bromide, dimethyl sulfide complex, 99% (54678‑23‑8) BrC2CuH6S; FW: 205.59; off-white to light-green pwdr. moisture sensitive

5g 25g

29-500129-5001

aHAZ

Copper(II) trifluoromethanesulfonate, 99% (99.9%-Cu) (Copper triflate) (34946‑82‑2) Cu(CF3SO3)2; FW: 361.68; light green solid air sensitive

Cu2+S

F

F

F

-O

O

O

S

F

F

F

O-O

O 5g 25g 100g

29-551529-5515 Trifluoromethylthiolato(2,2-bipyridine)copper(I), 97%

(1413732‑47‑4) C11H8CuF3N2S; FW: 320.80; red xtl. air sensitive, moisture sensitive

N N

Cu

SCF3

250mg 1g

Technical Notes:1. Catalyst for nucleophilic trifluoromethylthiolation of aryl halides.2. Catalyst for synthesis of α-trifluoromethylthio- and seleno-α,β-unsaturated carbonyl compounds.3. Catalyst for trifluoromethylthiolation of vinyl bromides.4. Catalyst for trifluoromethylthiolation of bromopyridines.

[(bpy)Cu(SCF3)]MeCN, 110°C, 115h

R R

X SCF3

X = Br, IR = H, Me, Ph, Cl, CO2Me, CN, NO2, OMe

Tech. Note (1)Ref. (1,2)

R1

[(bpy)Cu(ECF3)]nE = S, Se, n = 1, 2

Br

R2

O

R1

ECF3

R2

O

Tech. Note (2)Ref. (3)

R(bpy)Cu(SCF3)

KF, Diglyme

Br

R

SCF3

R = OMe, NMe, NO2, CF3, F, Cl, et al.

Tech. Note (3)Ref. (4)

N

R(bpy)Cu(SCF3)

Dioxane

Br

N

R

SCF3Tech. Note (4)Ref. (4)

References:1. Angew. Chem. Int. Ed. 2013, 52, 1548.2. Tetrahedron, 2013, 69, 6046.3. Tetrahedron, 2014, 70, 672.4. J. Org. Chem. 2015, 80, 2912.5. Adv. Synth. Catal. 2016, 358, 386.

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ELECTROPOLISHED STAINLESS STEEL BUBBLERS (Vertical)ELECTROPOLISHED STAINLESS STEEL BUBBLERS (Vertical)

95-400295-4002

a

Stainless steel bubbler, 1200ml, vertical, electropolished with fill-port, high temp valves (315°C), DOT 4B, UN stamped Note: See the Technical Note tab at strem.com for drawings.

1cyl

95-300095-3000

a

Stainless steel bubbler, 150ml, vertical, electropolished with fill-port, replaceable-seat valves with rotated handles, DOT 4B, UN stamped Note: See the Technical Note tab at strem.com for drawings.

1cyl

GERMANIUM (Compounds) 32-321532-3215

a

Germanium(II) chloride dioxane adduct (28595‑67‑7) C4H8Cl2GeO2; FW: 231.65 air sensitive, moisture sensitive

2g 10g

GOLD (Elemental Forms) 79-092179-0921

a

Gold nanoparticles, 1% on carbon black (surfactant and reactant-free) (7440‑57‑5) Au; FW: 196.70; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

79-091679-0916

a

Gold nanoparticles, 1% on Titania (anatase) (surfactant and reactant-free) (7440‑57‑5) Au; FW: 196.70; dark purple pwdr. (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

79-090579-0905

a

Gold nanoparticles, 1% on Titania (rutile) (surfactant and reactant-free) (7440‑57‑5) Au; FW: 196.70; purple solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

79-092679-0926

a

Gold nanoparticles, 5% on carbon black (surfactant and reactant-free) (7440‑57‑5) Au; FW: 196.70; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g25g

79-093579-0935

a

Gold nanoparticles, 10% on Titania (anatase) (surfactant and reactant-free) (7440‑57‑5) Au; FW: 196.70; purple solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

79-093079-0930

a

Gold nanoparticles, 10% on Titania (rutile) (surfactant and reactant-free) (7440‑57‑5) Au; FW: 196.70; dark purple solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g 5g

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GOLD (Compounds)GOLD (Compounds)

79-123079-1230

a

Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-1,3-dihydro-4,5-dimethyl-2H-im-idazol-2-ylidene}gold(I), 98% IPrMeAuCl (1192141‑66‑4) C29H40AuClN2; FW: 649.0; white pwdr. air sensitive

N N

iPr

iPr iPr

iPr

Au

Cl

Me Me 100mg 500mg

INDIUM (Compounds) 49-490149-4901

a

Indium(III) acetylacetonate (99.99+%-In) PURATREM (14405‑45‑9) In(CH3COCHCOCH3)3; FW: 412.15; off-white pwdr.; m.p. 180-185; b.p. 260-280 subl.; d. 1.41

In

OO

O

O O

O Me

Me

MeMe

Me

Me

5g 25g

IRIDIUM (Compounds) 77-022077-0220

a

(2,2’-Bipyridine)bis[3,5-difluoro-2-[5-(trifluoro-methyl)-2-pyridinyl-kN][phenyl-kC]iridium(III) hexafluorophosphate, 95% (1092775‑62‑6) C34H18F16IrN4P; FW: 1009.70; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photocatalyst used for the chemo-, regio, and stereoselective

trifluoromethylation of styrene.2. Photoredox catalyst used in cross-coupling: Ir/Ni dual

catalysts for the synthesis of benzylic ethers.3. Iridium complex used for catalytic olefin hydroamidation enabled by proton-coupled electron transfer.4. Catalyst used for visible light photoredox cross-coupling of acyl chlorides with potassium

alkoxymethyltrifluoroborates.5. Iridium catalyst used in the photoredox/nickel dual catalytic cross-coupling of secondary alkyl

β-trifluoroboratoketones and –esters with aryl bromides.6. Photocatalyst used in the cross-coupling of trifluoroalkylboranes.

Ar

NMe2

CF3

Ir complex (3 mol%) visible light

5-CF3(dibenzothio-phenium)+BF4

-

Tech. Note (1)Ref. (1)

BF3KRO +

Ir complex (2.0mol%)NiCl2(dme), (3 mol%) dtbbpy (3 mol%)

3.0 equiv K2HPO4 dioxane/DMA (5:1)2x26 W CFL, 24 h, rt

BrR' R'

BnO

0.6 mmol 0.5 mmole

Tech. Note (2)Ref. (2)

ArX

O R1

R2

H

NX

O Ar

H

R1 R2

10 mol% thiophene0.3M CH2Cl2. blue LED, rt

Ir complex (2 mol%) 20mol% NBu4OP(O)(OBu)2 Tech. Note (3)

Ref. (3)

N

NN

N

Ir

F3C

F

F3C

FPF6

-

F

F

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IRIDIUM (Compounds)

Cl

O

+ R2

O BF3K

OO

R2

Ir complex (2 mol%) NiCl2(dme), (4 mol%) 4-t-Bu(pyr)oxazoline (4 mol%)

additive dioxane 25°C 26W CFL 30 h

Tech. Note (4)Ref. (4)

Bn

BF3KMe

OBr

CN

Bn

Me

O

CN

Ir complex (2.5mol%)NiCl2(dme), (2.5 mol%) dtbbpy (2.5 mol%)

additive dioxane 25°C 26W CFL 30 h

+Tech. Note (5)Ref. (5)

BF3K

R+ ArBr

Ar

R

Ir complex (2.5mol%)NiCl2(dme), (5 mol%)

dtbbpy (5 mol%) Cs2CO3 (1.5 equiv)dioxane, 23W CFL 22h

Tech. Note (6)Ref. (6)

References:1. J. Org. Chem., 2014, 79, 10446.2. Org. Lett., 2015, 17, 3294.3. J. Am. Chem. Soc., 2015, 137, 13495.4. Org. Lett., 2016, 18, 732.5. Org. Lett., 2016, 18, 2994.6. Org. Lett., 2016, 18, 5760.

77-045377-0453

a

(2,2’-Bipyridine)bis[3,5-difluoro-2-[5-trifluoro-methyl-2-pyridinyl-kN)phenyl-kC]iridium(III) hexafluorophosphate, 99% (1092775‑62‑6) [Ir(C10H8N2)(C12H5F5N)2] PF6; FW: 1009.70; yellow pwdr. Note: Photocatalyst

N

NN

N

Ir

F3C

F

F3C

FPF6

-

F

F

50mg 250mg

Technical Notes:1. See 77-0220 (page 37)

77-0220(cont.)

(2,2’-Bipyridine)bis[3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-kN][phenyl-kC]iridium(III) hexafluorophosphate, 95% (1092775‑62‑6)

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IRIDIUM (Compounds)

Cl

O

+ R2

O BF3K

OO

R2

Ir complex (2 mol%) NiCl2(dme), (4 mol%) 4-t-Bu(pyr)oxazoline (4 mol%)

additive dioxane 25°C 26W CFL 30 h

Tech. Note (4)Ref. (4)

Bn

BF3KMe

OBr

CN

Bn

Me

O

CN

Ir complex (2.5mol%)NiCl2(dme), (2.5 mol%) dtbbpy (2.5 mol%)

additive dioxane 25°C 26W CFL 30 h

+Tech. Note (5)Ref. (5)

BF3K

R+ ArBr

Ar

R

Ir complex (2.5mol%)NiCl2(dme), (5 mol%)

dtbbpy (5 mol%) Cs2CO3 (1.5 equiv)dioxane, 23W CFL 22h

Tech. Note (6)Ref. (6)

References:1. J. Org. Chem., 2014, 79, 10446.2. Org. Lett., 2015, 17, 3294.3. J. Am. Chem. Soc., 2015, 137, 13495.4. Org. Lett., 2016, 18, 732.5. Org. Lett., 2016, 18, 2994.6. Org. Lett., 2016, 18, 5760.

77-045377-0453

a

(2,2’-Bipyridine)bis[3,5-difluoro-2-[5-trifluoro-methyl-2-pyridinyl-kN)phenyl-kC]iridium(III) hexafluorophosphate, 99% (1092775‑62‑6) [Ir(C10H8N2)(C12H5F5N)2] PF6; FW: 1009.70; yellow pwdr. Note: Photocatalyst

N

NN

N

Ir

F3C

F

F3C

FPF6

-

F

F

50mg 250mg

Technical Notes:1. See 77-0220 (page 37)

77-021877-0218

a

4,4’-Bis(t-butyl-2,2’-bipyridine]bis[5-methyl-2-(4-methyl-2-pyridinyl-kN)phenyl-kC]iridium hexafluorophosphate, 95% (1607469‑49‑7) C44H48F6IrN4P; FW: 970.06; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Note:1. Catalyst used for the direct β-alkylation of aldehydes via

photoredox organocatalysis.

O

H

n-pent

Ph

COOBn

O

H

n-pent

Ph

COOBn

+

1 mol% photocatalyst20 mol% organocatalyst

DABCO, TFA, H2O DME, 23°C, 24 h light source

Tech. Note (1)Ref. (1)

References:1. J. Am. Chem. Soc., 2014, 136, 6858.

77-184577-1845

a

Chloro(1,5-cyclooctadiene)[4,5-di-methyl-1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene] iridium(I), min. 98% (1118917‑09‑1) C31H40ClIrN2; FW: 668.33; yellow pwdr.; m.p. >200C (dec)

N N

Ir

Cl

MeMe

Me

Me Me

MeMe Me 100mg500mg

77-028577-0285

a

[4,4’-Di-t-butyl-2,2’-bipyridine][bis[5-(t-bu-tyl)-2-[4-(t-butyl)-2-pyridinyl-kN]phenyl-kC]iridium(III) hexafluorophosphate, 95% (808142‑80‑5) C56H72F6IrN4P; FW: 1138.38; yellow pwdr. air sensitive Note: Photocatalyst N

N

N

N

Ir PF6-

tBu

tBu

tBu

tButBu

tBu 50mg250mg

77-185077-1850

a

Dimethylphenylphosphine(1,5-cyclooctadiene)[1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene] iridium(I) tetrakis(3,5-bis(trifluoromethyl)phenylborate, min. 98% (1884137‑92‑1) C37H47IrN2P(C32H12BF24); FW: 1606.18; red solid; m.p. 146-149

N N

Ir

P(Ph)Me2

MeMe

Me

Me Me

Me

+

B[C6H3(CF3)2]4-

100mg500mg

77-184077-1840

a

Triphenylphosphine(1,5-cyclooctadiene)[1,3-bis(2,4,6-trimethylphenyl)imidaz-ol-2-ylidene] iridium(I) tetrakis(3,5-bis(tri-fluoromethyl)phenylborate, min. 98% (1628471‑64‑6) C47H51IrN2P(C32H12BF24); FW: 1730.32; red solid; m.p. > 156C (dec)

N N

Ir

PPh3

MeMe

Me

Me Me

Me

+

B[C6H3(CF3)2]4-

100mg500mg

N

N

NN

Ir PF6-

tBu

tBu

Me

MeMe

Me

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IRIDIUM (Compounds)77-703077-7030

a

Tris[2-(2,4-difluorophenyl)pyridine]iridium(III), 95% (387859‑70‑3) C33H18F6IrN3; FW: 762.72; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photoredox catalysis for trifluoromethylation of arenes and

heteroarenes.2. Photocatalyst for C–F alkenylation coupling reactions

between perfluoroarenes and alkynes.

Ir(F-ppy)3R

HR

CF3CF3SO2Cl Tech. Note (1)Ref. (1)

Ir(F-ppy)3 (0.25 mol%)FnR R' R'' Fn-1R

DIPEA, 0°C, MeCN

R'

R''Tech. Note (2)Ref. (2)

References:1. Nature, 2011, 480, 224.2. Chem. Sci., 2016, 7, 6796.

77-610077-6100

a

Tris[5-fluoro-2-(2-pyridinyl-kN)phenyl-kC]iridium(III), 95% (370878‑69‑6) C33H21F3IrN3; FW: 708.75; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photosensitizer for the enantioselective coupling reaction

between (N-arylamino)methanes and (N-methanesulfonyl)-aldimines catalyzed by P-Spiro chiral (arylamino)phosphonium catalyst.

2. Photocatalyst for [2+2] styrene cycloadditions.3. Photocatalyst for azoylation of trimethoxybenzene by via C−H functionalization.

HN

NH

HN

NH

P

Ar

Ar BArF

Ph H

NMs

+ NPh

Ph

PhNPh

HNMs

GG = H, Me3Si

Ir(Fppy)3; light; RT, 24

Tech. Note (1)Ref. (1)

O

RPh Me

Me

Ph

R H

MeMe

1 mol% Ir(Fppy)3

light, DMSO

R = H, Me

Tech. Note (2)Ref. (2)

S

NBr +

OCH3

H3CO OCH3

OCH3

H3CO OCH3

N S

Ir(Fppy)3 (0.3%)N-cyclohexyl-N-

sobutylcyclohexanamine (0.5 equiv)

K2CO3 (2 equiv), Blue LEDs, Ar,30°C, MeCN (0,05 M)

Tech. Note (3)Ref. (3)

References:1. J. Org. Chem., 2016, 81, 6953.2. Chem. Sci., 2016, 7, 6796.3. Org. Lett., 2016, 18, 3996.

N N

N

Ir

F

F F

F

FF

N N

N

Ir

F

F

F

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IRIDIUM (Compounds)77-703077-7030

a

Tris[2-(2,4-difluorophenyl)pyridine]iridium(III), 95% (387859‑70‑3) C33H18F6IrN3; FW: 762.72; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photoredox catalysis for trifluoromethylation of arenes and

heteroarenes.2. Photocatalyst for C–F alkenylation coupling reactions

between perfluoroarenes and alkynes.

Ir(F-ppy)3R

HR

CF3CF3SO2Cl Tech. Note (1)Ref. (1)

Ir(F-ppy)3 (0.25 mol%)FnR R' R'' Fn-1R

DIPEA, 0°C, MeCN

R'

R''Tech. Note (2)Ref. (2)

References:1. Nature, 2011, 480, 224.2. Chem. Sci., 2016, 7, 6796.

77-610077-6100

a

Tris[5-fluoro-2-(2-pyridinyl-kN)phenyl-kC]iridium(III), 95% (370878‑69‑6) C33H21F3IrN3; FW: 708.75; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photosensitizer for the enantioselective coupling reaction

between (N-arylamino)methanes and (N-methanesulfonyl)-aldimines catalyzed by P-Spiro chiral (arylamino)phosphonium catalyst.

2. Photocatalyst for [2+2] styrene cycloadditions.3. Photocatalyst for azoylation of trimethoxybenzene by via C−H functionalization.

HN

NH

HN

NH

P

Ar

Ar BArF

Ph H

NMs

+ NPh

Ph

PhNPh

HNMs

GG = H, Me3Si

Ir(Fppy)3; light; RT, 24

Tech. Note (1)Ref. (1)

O

RPh Me

Me

Ph

R H

MeMe

1 mol% Ir(Fppy)3

light, DMSO

R = H, Me

Tech. Note (2)Ref. (2)

S

NBr +

OCH3

H3CO OCH3

OCH3

H3CO OCH3

N S

Ir(Fppy)3 (0.3%)N-cyclohexyl-N-

sobutylcyclohexanamine (0.5 equiv)

K2CO3 (2 equiv), Blue LEDs, Ar,30°C, MeCN (0,05 M)

Tech. Note (3)Ref. (3)

References:1. J. Org. Chem., 2016, 81, 6953.2. Chem. Sci., 2016, 7, 6796.3. Org. Lett., 2016, 18, 3996.

N N

N

Ir

F

F F

F

FF

N N

N

Ir

F

F

F

77-701577-7015

a

Tris(2-phenylpyridinato-C2,N)iridium(III), 95% (94928‑86‑8) C33H24IrN3; yellow pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photocatalyst for α-amino C–H arylation of cyano(hetero)arenes

by tertiary amines2. Photocatalyst for trifluoromethylation of alkenes and alkynes3. Photocatalyst for reduction of alkyl, alkenyl, aryl iodides (a) and

intramolecular reductive cyclizations (d)4. Photocatalyst for organocatalyst assisted direct arylation of allylic sp3 C–H bonds5. Photocatalyst for the generation multifluorinated biaryls via functionalization of the C−F bond of a

perfluoroarene and C−H bond of the other arene in the presence of amines6. Photocatalyst for visible-light photoredox arylation of thiols with various aryl halides

0.5-1.0 mol% fac-Ir(ppy)3, 26 WNaOAc, DMA, 23°C, 12h

R2 N R3

R1

CN

CN CN

N

R3

R1R2 Tech. Note (1)

Ref. (1)

R CF3R1 R3R2

orCF3 + R1

ORR2

CF3

R3fac-Ir(ppy)3 or Tech. Note (2)Ref. (2,3)

fac-Ir(ppy)3 (1.0 mol%)Bu3N (2.0 equiv.)

R I, Ar I, R1

R2I

R2

R H, Ar H, R1

R2H

R2

Hantzsch ester* or HCO2HMeCN, visible light

Tech. Note (3)Ref. (4)

fac-[Ir(ppy)3]Organocatalyst

H N

Y

NTech. Note (4)Ref. (5)

fac-[Ir(ppy)3] (0.25 mol%), DIPEA 1.2-6.0 equiv

K2CO3, MeCN, 0°C, blue LED, ArFnR Fn-1RArene–H

+HF*Base

Arene

Tech. Note (5)Ref. (6)

YY

YR1

XR2

SH

+

X=I, Br, Cl, FY=CH, N

[fac-Ir(ppy)]3, Cs2CO3, DMF, Ar

RT, 23 W CFLY

Y

YR1

SR2

Tech. Note (6)Ref. (7)

References:1. Science 2011, 334, 11142. Angew. Chem. Int. Ed. 2012, 51, 95673. Angew. Chem. Int. Ed. 2014, 53, 5394. Nat. Chem. 2012, 4, 8545. Nature 2015 519, 746. J. Am. Chem. Soc. 2016, 138, 25207. Angew. Chem. Int. Ed. 2017, 56, 874

N N

N

Ir

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IRIDIUM (Compounds)77-658077-6580

a

Tris[(2-(2-pyridinyl-kN)-5-(trifluoromethyl)phenyl-kC]iridium(III), 95% (500295‑52‑3) C36H21F9IrN3; FW: 858.78; yellow solid air sensitive Note: Photocatalyst N N

N

Ir

CF3

CF3

F3C 50mg 250mg

IRON (Compounds) 26-087326-0873

a

Bromocarbonyl[(1S,2S)-2,3-diphenylethylenediamine-N,N’-bis(2-diphenylphosphinoethyllidene)]iron(II) tetraphenylborate, FeATHer-II Catalyst (1257252‑03‑1) C67H65BBrFeN2OP2; FW: 1122.75; yellow pwdr. air sensitive, moisture sensitive Note: Sold in collaboration with GreenCentre for research purposes only. Patents: PCT/CA2013/050405, PCT 2013/010275.

N N

P P

Ph Ph

Ph

Fe

Br

C

OPh

PhPh

BPh4-

100mg500mg

Technical Note:1. Catalyst used in the transfer hydrogenation of ketones and imines.

O

C

R2R1 R1

C

HO

H

R20.016 to 0.05 mol% Fe catalyst 0.033 - 0.40 mol% KOtBu

iPrOH, 28 °C10s to 1 hour

Tech. Note (1)Ref. (1)

N

MeR1 R1

HN

H

Me

PPh2

O

PPh2

O

iPrOH, 28 °C10 s to 3 min

1.0 mol% Fe cat. 8 mol% KOtBu Tech. Note (1)

Ref. (1)

References:1. Science, 2013, 342, 1080.

26-124026-1240

a

1-Diphenylphosphino-1’-(di-t-butylphosphino)ferrocene, 97% (95408‑38‑1) C30H36FeP2; FW: 514.40; yellow to orange pwdr.; m.p. 75-79° air sensitive

Fe

PPh2

(tBu)2P

250mg 1g

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LANTHANUM (Compounds)77-658077-6580

a

Tris[(2-(2-pyridinyl-kN)-5-(trifluoromethyl)phenyl-kC]iridium(III), 95% (500295‑52‑3) C36H21F9IrN3; FW: 858.78; yellow solid air sensitive Note: Photocatalyst N N

N

Ir

CF3

CF3

F3C 50mg 250mg

IRON (Compounds) 26-087326-0873

a

Bromocarbonyl[(1S,2S)-2,3-diphenylethylenediamine-N,N’-bis(2-diphenylphosphinoethyllidene)]iron(II) tetraphenylborate, FeATHer-II Catalyst (1257252‑03‑1) C67H65BBrFeN2OP2; FW: 1122.75; yellow pwdr. air sensitive, moisture sensitive Note: Sold in collaboration with GreenCentre for research purposes only. Patents: PCT/CA2013/050405, PCT 2013/010275.

N N

P P

Ph Ph

Ph

Fe

Br

C

OPh

PhPh

BPh4-

100mg500mg

Technical Note:1. Catalyst used in the transfer hydrogenation of ketones and imines.

O

C

R2R1 R1

C

HO

H

R20.016 to 0.05 mol% Fe catalyst 0.033 - 0.40 mol% KOtBu

iPrOH, 28 °C10s to 1 hour

Tech. Note (1)Ref. (1)

N

MeR1 R1

HN

H

Me

PPh2

O

PPh2

O

iPrOH, 28 °C10 s to 3 min

1.0 mol% Fe cat. 8 mol% KOtBu Tech. Note (1)

Ref. (1)

References:1. Science, 2013, 342, 1080.

26-124026-1240

a

1-Diphenylphosphino-1’-(di-t-butylphosphino)ferrocene, 97% (95408‑38‑1) C30H36FeP2; FW: 514.40; yellow to orange pwdr.; m.p. 75-79° air sensitive

Fe

PPh2

(tBu)2P

250mg 1g

LANTHANUM (Compounds)

57-050557-0505

a

Lanthanum(III) bromide, anhydrous (99.99%-La) (REO) PURATREM (13536‑79‑3) LaBr3; FW: 378.62; white xtl. air sensitive, moisture sensitive

2g 10g

57-125057-1250

a

Tris[N,N,N,N-tetramethylguanidinium][tris(1S)-(1,1’-binaphalene)-2,2’-diolato]lanthanate La-HTMG-B (1611526‑71‑6) C75H78N9O6La; FW: 1340.38; tan pwdr. Note: U.S. Patent 14/898,925.

250mg 1g

Technical Notes:1. Catalyst used for an asymmetric Michael addition.2. Catalyst used for an asymmetric Michael addition of

1,3-dicarbonyls to enones.3. Catalyst used for the asymmetric aza-Michael addition of

methylhydroxylamine to chalcone derivatives.4. Catalyst used for the asymmetric direct aldol reaction of

acetophenone and pivaldehyde.

OO

BnO

O

OBn

O

OBnO

O

OBn*

Lan. catalyst (10 mole%) Na-X (30 mole%) H2O (X moles)

THF, 25°C, 12 h

+ Tech. Note (1)Ref. (1)

OO

R1O

O

OR1

O

OR1O

O

OR1

*

Lan. catalyst (10 mole%) NaI (3x mole%) H2O (3x mole%)

THF, 0°C, 12 h

+

R2R2

Tech. Note (2)Ref. (1)

O

Ar1 Ar2 CH3ONH2+O

Ar1 Ar2

NHOCH3

Lan. catalyst (x mole%) LiI (3x mole%) Drierite 1 equiv

THF, -20°C, 48 h *

Tech. Note (3)Ref. (1)

O

t-Bu H+

O

Ph

OH

t-Bu Ph

O

*

Lan. catalyst (8 mole%) Li-I (24 mol%) KO(tBu) (8 mol%) H2O (16 mol%)

THF, -20°C, 20 h

Tech. Note (4)Ref. (1)

References:1. J. Am. Chem. Soc., 2014, 136, 8034.

MANGANESE (Compounds) 25-134525-1345

a

Manganese(II) chloride anhydrous (99.995%-Mn) PURATREM (7773‑01‑5) MnCl2; FW: 125.84; pink solid; m.p. 650°; b.p. 1190°; d. 2.98 hygroscopic

5g 25g 100g

OO

La

OO

OO

NMe2

N NMe2+HH

Me2N

NMe2N + HH

NMe2

N

Me2N

HH+

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METALS SCAVENGING AGENTS (Compounds)METALS SCAVENGING AGENTS (Compounds)

07-220307-2203

a

1,4-Bis(2-isocyanopropyl)piperazine (SnatchCat Metal Scavenger) (51641‑96‑4) C12H20N4; FW: 220.31; white xtl. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 14/443,048; PCT/IB2014/062564.

NN

NC

CN

1g 5g

Technical Note:1. SnatchCat represents a universal tool for metal removal with a proven efficiency for Ru and Pd metals. The

product is an immediate metathesis reaction quencher, allowing reduced metal content to 10ppm after 20 min scavenging time and a simple workup by silica gel filtration. Compatible with a broad range of functional groups and solvents, the product is stable, non-toxic, non-volatile and odor-free.

COOEt

PhO 1. Nitro-Grela, 1 mol%

70°C, 60 min

2. SnatchCat 70°C, 30 min3. Filtration through silica gel

COOEt

PhO

N Br N

1. PhB(OH)2

(PPh3)2PdCl2 (5 mol%)

2. SnatchCat, 30 min3. Filtration through silica gel

Tech. Note (1)Ref. (1)

References:1. ChemSus Chem., 2015, 8, 4139.

06-152206-1522

a

Chelating/scavenger resin with aminophosphonic - S940 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 425-850 micron; Purolite S940 is a chelating resin of macroporous structure, with a polystyrene matrix crosslinked with divinylbenzene (DVB) substituted with weakly acidic aminophosphonic active groups. This chemical structure facilitates the formation of complexes with metallic ions. The aminophosphonic chelating resins have a greater affinity for certain cations, and form more stable complexes with cations of low atomic mass metals than their iminodiacetic resin counterparts. Hence Purolite S940 is capable of fixing one or more specific cations from a larger range even from solutions which are highly concentrated. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-152506-1525

a

Chelating/scavenger resin with aminophosphonic - S950 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1000 micron; Purolite S950 is a macroporous aminophosphonic acid chelating resin, designed for the removal of cations of toxic metals such as lead, copper and zinc from industrial effluents at low pH. At somewhat higher pH values, calcium, magnesium and barium, as well as the toxic metals cadmium, nickel, and cobalt are strongly complexed and may be separated from quite high concentrations of univalent cations. Purolite S950 is highly selective (under the appropriate conditions) for a range of both heavy metal and common divalent ions. Hence its use may be recommended where it is necessary to remove calcium or magnesium in order to avoid possible precipitation, or where its selectivity for a particular range of metals offers advantages. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

New Products Introduced Since Chemiker XXIX (July 2016)

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METALS SCAVENGING AGENTS (Compounds)METALS SCAVENGING AGENTS (Compounds)

07-220307-2203

a

1,4-Bis(2-isocyanopropyl)piperazine (SnatchCat Metal Scavenger) (51641‑96‑4) C12H20N4; FW: 220.31; white xtl. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 14/443,048; PCT/IB2014/062564.

NN

NC

CN

1g 5g

Technical Note:1. SnatchCat represents a universal tool for metal removal with a proven efficiency for Ru and Pd metals. The

product is an immediate metathesis reaction quencher, allowing reduced metal content to 10ppm after 20 min scavenging time and a simple workup by silica gel filtration. Compatible with a broad range of functional groups and solvents, the product is stable, non-toxic, non-volatile and odor-free.

COOEt

PhO 1. Nitro-Grela, 1 mol%

70°C, 60 min

2. SnatchCat 70°C, 30 min3. Filtration through silica gel

COOEt

PhO

N Br N

1. PhB(OH)2

(PPh3)2PdCl2 (5 mol%)

2. SnatchCat, 30 min3. Filtration through silica gel

Tech. Note (1)Ref. (1)

References:1. ChemSus Chem., 2015, 8, 4139.

06-152206-1522

a

Chelating/scavenger resin with aminophosphonic - S940 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 425-850 micron; Purolite S940 is a chelating resin of macroporous structure, with a polystyrene matrix crosslinked with divinylbenzene (DVB) substituted with weakly acidic aminophosphonic active groups. This chemical structure facilitates the formation of complexes with metallic ions. The aminophosphonic chelating resins have a greater affinity for certain cations, and form more stable complexes with cations of low atomic mass metals than their iminodiacetic resin counterparts. Hence Purolite S940 is capable of fixing one or more specific cations from a larger range even from solutions which are highly concentrated. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-152506-1525

a

Chelating/scavenger resin with aminophosphonic - S950 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1000 micron; Purolite S950 is a macroporous aminophosphonic acid chelating resin, designed for the removal of cations of toxic metals such as lead, copper and zinc from industrial effluents at low pH. At somewhat higher pH values, calcium, magnesium and barium, as well as the toxic metals cadmium, nickel, and cobalt are strongly complexed and may be separated from quite high concentrations of univalent cations. Purolite S950 is highly selective (under the appropriate conditions) for a range of both heavy metal and common divalent ions. Hence its use may be recommended where it is necessary to remove calcium or magnesium in order to avoid possible precipitation, or where its selectivity for a particular range of metals offers advantages. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-150806-1508

a

Chelating/scavenger resin with aminoxime - S910 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Purolite® S910 is an amidoxime chelating resin, designed for the removal of cations of metals such as copper and iron from water or other solvent even at relatively low pH. It can also be used for the recovery of traces of precious metals from dilute solutions. It cannot be used for removal of alkaline earth metals. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-153006-1530

a

Chelating/scavenger resin with bispicolylamine - S960 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 425-1000 micron; Purolite® S960 is a macroporous poly-styrene divinylbenzene copolymer within which weakly basic bis-picolylamine chelating functional groups are covalently bonded. This resin has high selectivity for metals such as nickel, copper, and cobalt as compared to iron, aluminum, calcium, and magnesium. Purolite® S960 is active within the pH range of 0 8 and may function outside that range depending on the metals involved. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

06-152006-1520

a

Chelating/scavenger resin with iminodiacetic - S930Plus spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 425-1000 micron; Purolite S930Plus is a macroporous polystyrene; based chelating resin, with iminodiacetic groups designed for the removal of heavy metals from industrial effluents. Purolite S930Plus finds use in processes for extraction and recovery of metals from ores, galvanic plating solutions, pickling baths and effluents. Further uses include the decalcification of brine for chloralkali processes, where Purolite S930Plus shows advantages under certain operating conditions over the typically used aminophosphonic type resins such as Purolite S940. Purolite S930Plus has high selectivity and capacity for hardness and strontium and has excellent osmotic stability. Purolite S930Plus is susceptible to oxidation. Hence direct treatment of brine solutions containing free chlorine should be avoided, for instance by preliminary reaction with sulphur dioxide, sulphide or, by use of a treatment with activated carbon. Brine solutions can often contain significant concentrations of chlorates. In this case it is necessary to ensure that the displacement rinse prior to the acid regeneration is efficient, so as to avoid the formation of free chlorine from contact of chlorates in the brine solution with the regeneration acid. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-151406-1514

a

Chelating/scavenger resin with isothiouronium - S920Plus spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Purolite® S920Plus is a macroporous polystyrenic based chelating resin, with thiouronium groups designed for the selective removal of mercury and for the recovery of precious metals from industrial effluents. Mercury is strongly bound to the functional groups to form highly stable complexes, with high selective affinity compared with those of other heavy metals. These properties are largely unaffected by high chloride (or sulfate) content of the effluent. Effluent solutions which may typically contain 2 - 20 ppm of mercury can be treated to reduce the concentration in solution to less than 0.005 ppm. Purolite S920Plus can load up to 200g of mercury, or gold, or approximately 60g of platinum or palladium for each liter of resin, equivalent to 12.5, and 3.75 lb/ft3 respectively. Purolite S920Plus is designed for the removal of low concentrations of soluble mercury salts from waste streams and for the recovery of precious metals from rinse waters in the galvanic and electronic industries. It is also used in hydrometallurgy for the separation of precious metals from acid liquors. Mercury and precious metals are so strongly held, and run lengths are so long (thousands of hours) that it is not normally considered economic to regenerate the resin for reuse. Purolite S920Plus is more resistant to oxidation than many thiol based resins and contact with the atmosphere is not detrimental, however free chlorine and other strong oxidizing agents may damage the resin and their removal from solution by filtering through activated carbon is recommended. Sold in collaboration with Purolite for research purposes only.

50g5x50g

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METALS SCAVENGING AGENTS (Compounds)06-150106-1501

a

Chelating/scavenger resin with N-methylglucamine - S108 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 425-630 micron; Purolite® S108 is a macroporous polystyrenic based resin with excellent kinetics and functional groups specially designed for the selective removal of salts of boron from aqueous solutions. It is effective for such solutions over a wide range of pH values, and over a wide range of boron concentrations. The presence of boron ions in water for potable and agriculture/horticulture use, even in relatively small (ppm) concentrations can give rise to major problems. Even where concentrations of other ions are reasonably high, Purolite® S108 will reduce boron concentrations by an order of magnitude. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-152806-1528

a

Chelating/scavenger resin with phosphonic and sulfonic acid - S957 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 425-1000 micron; Purolite S957 is a specially developed Monophos chelating resin, which incorporates phosphonic, and sulfonic functional groups on a mechanically and osmotically resistant matrix. These combined properties give it high selectivity for iron and other transitional metals, even in acidic solutions. Purolite S957 has been especially designed for the selective removal of ferric iron from acidic solutions, such as copper electrolyte or from nickel, cobalt and zinc processing solutions. Purolite S957 can also be used in potable water applications for the selective removal of trace levels of selected metals from neutral pH waters. Its selectivity for uranium and other lanthanide elements should give good opportunities for its successful employment in other areas. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-153206-1532

a

Chelating/scavenger resin with polyamine - S985 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Purolite® S985 is a high capacity, macroporous, weak base anion exchange resin with a polyacrylic matrix supporting functional groups of the polyamine type. The carefully formulated, macroporous acrylic matrix ensures excellent exchange kinetics for the removal of trace heavy metals from waste water streams and the special polyamine functionality produces very interesting operating capacities and makes the uptake of metallic cations possible even when they are present in the waste stream as organic anionic complexes. Its tough and resilient macroporous structure also affords excellent mechanical, strength and resistance to osmotic shock. Sold in collaboration with Purolite for research purposes only.

50g5x50g

06-151806-1518

a

Chelating/scavenger resin with thiol - S924 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1000 micron; Purolite S924 is a chelating resin, polystyrene based and designed for the selective removal of mercury. The mercury is strongly bound to the functional groups to form highly stable complexes with high selective affinity compared with those of other heavy metals. Even so the high selectivity for metals such as silver, copper, lead, cadmium, nickel and cobalt, makes this resin useful in waste treatment and hydrometallurgical processes. The high selectivity for mercury is largely unaffected by high chloride or sulphate content of the effluent. Effluent solutions that may typically contain 0.01-25ppm of mercury can be treated to reduce the concentration to significantly less than 5ppb residual mercury. Purolite S924 can load up to 150 g (16 lb/cu.ft) of mercury per litre of resin. Purolite S924 is designed for the removal of moderately low concentrations of soluble mercury salts from brine streams used to produce caustic soda and chlorine where mercury cells are used, and may be regenerated with concentrated hydrochloric acid solutions. In the process for the manufacture of caustic soda and chlorine from brine, where all or part of the production uses mercury cells, the mercury rich regenerant acid may be neutralized with the sodium hydroxide to produce a recovered brine solution that may be recycled to the mercury cell process. Mercury may be present at very low concentrations and consequently run lengths are often long (thousands of hours). It is sometimes not economic to regenerate the resin for re-use. In such cases Purolite S920 may be preferred because of its higher capacity. Purolite S924 is prone to oxidation and long-term contact with the atmosphere is detrimental. It is recommended that this resin is shipped and stored under water. Also, free chlorine and other strong oxidizing agents may damage the resin. Their removal from solution by filtering through activated carbon is recommended. Sold in collaboration with Purolite for research purposes only.

50g5x50g

New Products Introduced Since Chemiker XXIX (July 2016)

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METALS SCAVENGING AGENTS (Compounds)06-151206-1512

a

Chelating/scavenger resin with thiourea - S914 spherical beads (wet) (store cold) Note: Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; Particle Size: 300-1200 micron; Purolite S914 is a macroporous type chelating resin with thiourea functionality. It has very high selectivity for mercury and platinum group metals such as platinum, gold and silver. Purolite S914 is stable over the whole pH range. The applications include mercury removal from brine and effluent in chloralkali process, mercury removal from flue gas scrubber effluent, recovery of platinum group metals from effluents amongst others. Sold in collaboration with Purolite for research purposes only.

50g 5x50g

MOFS AND LIGANDS FOR MOF SYNTHESIS (Compounds) 22-1070 Hexakis[μ-(2-amino-1,4-benzenedicarboxylato)][tetra-μ-hydroxyoc-

ta-μ-oxooctatitanium], NH2-MIL-125(Ti), CONEKTIC™ T125 (1309760‑94‑8)See page 96

40-1109 Zirconium aminobenzenedicarboxylate MOF (UiO-66-BDC-NH2, BDC-NH2:Zr=0.9-1.0) (1260119‑00‑3)See page 97

40-1108 Zirconium benzenedicarboylate MOF (UiO-66-BDC, BDC:Zr=0.66-0.98)See page 98

40-1112 Zirconium biphenyldicarboxylate MOF (UiO-66-BPDC/UiO-67, BPDC:Zr=0.9-1.0)See page 98

40-1114 Zirconium Fumarate MOF (UiO-66-FA, FA:Zr=0.66-0.98)See page 99

40-1106 Zirconium trans-1, 2-ethylenedicarboxylic acid MOF (UiO-66-FA, FA:Zr=1)See page 99

40-1111 Zirconium trimellitate MOF (UiO-66-BDC-COOH, BDC-COOH:Zr=0.9-1.0)See page 100

NANOMATERIALS (Elemental Forms) 79-0921 Gold nanoparticles, 1% on carbon black (surfactant and reactant-free)

(7440‑57‑5)See page 36

79-0916 Gold nanoparticles, 1% on Titania (anatase) (surfactant and reac-tant-free) (7440‑57‑5)See page 36

79-0905 Gold nanoparticles, 1% on Titania (rutile) (surfactant and reactant-free) (7440‑57‑5)See page 36

79-0926 Gold nanoparticles, 5% on carbon black (surfactant and reactant-free) (7440‑57‑5)See page 36

79-0935 Gold nanoparticles, 10% on Titania (anatase) (surfactant and reac-tant-free) (7440‑57‑5)See page 36

79-0930 Gold nanoparticles, 10% on Titania (rutile) (surfactant and reactant-free) (7440‑57‑5)See page 36

06-2530 Graphene oxide (4mg/ml water dispersion) - low Mn. (1034343‑98‑0)See page 33

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NANOMATERIALS (Elemental Forms)06-033006-0330

a

Graphene Quantum Dots (GQDs), Aqua-Green Luminescent (1034343‑98‑0) C; dark red-brown pwdr. light sensitive, (store cold) Note: Particle diameter: <5 nm. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100mg

Suggested Applications:Graphene quantum dots (GQDs), sheets of few-layered graphene and lateral dimensions smaller than 100nm possess strong quantum confinement and edge effects. Thus, they possess unique physical properties such as strong photoluminescence, which can be tailored for specific applications by controlling their size, shape, defects and functionality.

In contrast to classic QDs, such as metal or silicon quantum dots, GQDs are biocompatible, photostable and inherit superior thermal, electrical and mechanical properties from the graphene. These features can greatly contribute to various state-of-the-art applications: optical brighteners, taggants for security applications1, bioimaging markers2, flu-orescent polymers3, antibacterial4, antibiofouling5, and disinfection systems6, heavy metals7, humidity and pressure8 sensors, batteries9, flash memory devices10, photovoltaic devices11 and light-emitting diodes12.

Item #Photoluminescence

QY+ * λmax * Max emission FWHM *06-0330 / 06-0332 >17% 485 nm 525 nm 70 nm06-0334 / 06-0336 >65% 350 nm 445 nm 65 nm

06-0340 >25% 420 nm 490 nm 80 nmAbbreviations

QY+

λmax

FWHM

Quantum YieldMaximum excitation wavelengthFull width at half maximum

20nm

References:1. http://onlinelibrary.wiley.com/doi/10.1002/anie.201206791/abstract2. http://onlinelibrary.wiley.com/doi/10.1002/ppsc.201400219/abstract3. http://pubs.acs.org/doi/abs/10.1021/acsami.5b060574. http://pubs.acs.org/doi/abs/10.1021/acsami.6b017655. http://www.nature.com/articles/srep201426. http://pubs.acs.org/doi/abs/10.1021/nn501640q7. http://www.sciencedirect.com/science/article/pii/S00134686150004688. http://pubs.acs.org/doi/abs/10.1021/nl40034439. http://pubs.acs.org/doi/abs/10.1021/nl504038s10. http://iopscience.iop.org/article/10.1088/0957-4484/25/25/255203/meta11. http://onlinelibrary.wiley.com/doi/10.1002/anie.200906291/abstract12. http://link.springer.com/article/10.1007/s10853-012-7016-8

06-033206-0332

a

Graphene Quantum Dots (GQDs) in water, Aqua-Green Luminescent (1034343‑98‑0) C; cloudy orange liq. light sensitive, (store cold) Note: Particle diameter: <5 nm. Concentration: 1 mg/ml. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100ml

Technical Note:1. See 06-0330 (page 48)

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NANOMATERIALS (Elemental Forms)06-033006-0330

a

Graphene Quantum Dots (GQDs), Aqua-Green Luminescent (1034343‑98‑0) C; dark red-brown pwdr. light sensitive, (store cold) Note: Particle diameter: <5 nm. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100mg

Suggested Applications:Graphene quantum dots (GQDs), sheets of few-layered graphene and lateral dimensions smaller than 100nm possess strong quantum confinement and edge effects. Thus, they possess unique physical properties such as strong photoluminescence, which can be tailored for specific applications by controlling their size, shape, defects and functionality.

In contrast to classic QDs, such as metal or silicon quantum dots, GQDs are biocompatible, photostable and inherit superior thermal, electrical and mechanical properties from the graphene. These features can greatly contribute to various state-of-the-art applications: optical brighteners, taggants for security applications1, bioimaging markers2, flu-orescent polymers3, antibacterial4, antibiofouling5, and disinfection systems6, heavy metals7, humidity and pressure8 sensors, batteries9, flash memory devices10, photovoltaic devices11 and light-emitting diodes12.

Item #Photoluminescence

QY+ * λmax * Max emission FWHM *06-0330 / 06-0332 >17% 485 nm 525 nm 70 nm06-0334 / 06-0336 >65% 350 nm 445 nm 65 nm

06-0340 >25% 420 nm 490 nm 80 nmAbbreviations

QY+

λmax

FWHM

Quantum YieldMaximum excitation wavelengthFull width at half maximum

20nm

References:1. http://onlinelibrary.wiley.com/doi/10.1002/anie.201206791/abstract2. http://onlinelibrary.wiley.com/doi/10.1002/ppsc.201400219/abstract3. http://pubs.acs.org/doi/abs/10.1021/acsami.5b060574. http://pubs.acs.org/doi/abs/10.1021/acsami.6b017655. http://www.nature.com/articles/srep201426. http://pubs.acs.org/doi/abs/10.1021/nn501640q7. http://www.sciencedirect.com/science/article/pii/S00134686150004688. http://pubs.acs.org/doi/abs/10.1021/nl40034439. http://pubs.acs.org/doi/abs/10.1021/nl504038s10. http://iopscience.iop.org/article/10.1088/0957-4484/25/25/255203/meta11. http://onlinelibrary.wiley.com/doi/10.1002/anie.200906291/abstract12. http://link.springer.com/article/10.1007/s10853-012-7016-8

06-033206-0332

a

Graphene Quantum Dots (GQDs) in water, Aqua-Green Luminescent (1034343‑98‑0) C; cloudy orange liq. light sensitive, (store cold) Note: Particle diameter: <5 nm. Concentration: 1 mg/ml. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100ml

Technical Note:1. See 06-0330 (page 48)

06-033406-0334

a

Graphene Quantum Dots (GQDs), Blue Luminescent (1034343‑98‑0) C; dark brown pwdr. light sensitive, (store cold) Note: Particle diameter: <5 nm. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100mg

Technical Note:1. See 06-0330 (page 48)

06-033606-0336

a

Graphene Quantum Dots (GQDs) in water, Blue Luminescent (1034343‑98‑0) C; cloudy colorless liq. light sensitive, (store cold) Note: Particle diameter: <5 nm. Concentration: 1 mg/ml. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100ml

Technical Note:1. See 06-0330 (page 48)

06-034006-0340

a

Graphene Quantum Dots (GQDs) in water, Cyan Luminescent (1034343‑98‑0) C; cloudy brown liq. light sensitive, (store cold) Note: Particle diameter: <5 nm. Concentration: 1 mg/ml. Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK.

100ml

Technical Note:1. See 06-0330 (page 48)

96-7410 Graphene Quantum Dots (GQDs) Master Kit (1034343‑98‑0)

See page 108 96-7425 Graphene Quantum Dots (GQDs) Mini Kit (Powders) (1034343‑98‑0)

See page 108 96-7420 Graphene Quantum Dots in water (GQDs) Mini Kit (Liquids) (1034343‑98‑0)

See page 109 06-0365 High Strength Metallurgical Graphene on GLASS HSMG® (10x10mm) (1034343‑98‑0)

See page 34 06-0345 High Strength Metallurgical Graphene on PMMA HSMG® (10x10 mm) (1034343‑98‑0)

See page 34 06-0355 High Strength Metallurgical Graphene on PMMA HSMG® (25x25mm) (1034343‑98‑0)

See page 34 06-0360 High Strength Metallurgical Graphene on PMMA HSMG® (50x50mm) (1034343‑98‑0)

See page 34 28-0015 Nickel/palladium alloy nanoparticle on graphene (G-Ni33Pd67)

See page 62 78-3015 Platinum nanoparticles, 1% on carbon black (surfactant and reactant-free) (7440‑06‑4)

See page 80 78-3020 Platinum nanoparticles, 5% on carbon black (surfactant and reactant-free) (7440‑06‑4)

See page 80 78-3030 Platinum nanoparticles, 10% on carbon black (surfactant and reactant-free) (7440‑06‑4)

See page 80 78-3032 Platinum nanoparticles, 20% on carbon black (surfactant and reactant-free) (7440‑06‑4)

See page 80 78-3035 Platinum nanoparticles, 30% on carbon black (surfactant and reactant-free) (7440‑06‑4)

See page 80 78-3012 Platinum nanoparticles, 1% on Titania (anatase) (surfactant and reactant-free) (7440‑06‑4)

See page 81 78-3005 Platinum nanoparticles, 1% on Titania (rutile) (surfactant and reactant-free) (7440‑06‑4)

See page 81 78-3026 Platinum nanoparticles, 10% on Titania (anatase) (surfactant and reactant-free) (7440‑06‑4)

See page 81 78-3023 Platinum nanoparticles, 10% on Titania (rutile) (surfactant and reactant-free) (7440‑06‑4)

See page 81

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NANOMATERIALS (Compounds)NANOMATERIALS (Compounds)

14-6100 High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~700 m2/g, (KCC-1 L1) (112945‑52‑5)See page 92

14-6110 High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~600 m2/g, (KCC-1 L2) (112945‑52‑5)See page 93

14-6120 High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~550 m2/g (KCC-1 L3) (112945‑52‑5)See page 93

14-6200 High Surface area Silica nanoparticles, medium, particle size ~400-450 nm, surface area ~400 m2/g, (KCC-1 M1) (112945‑52‑5)See page 93

14-6210 High Surface area Silica nanoparticles, medium, particle size ~300-350 nm, surface area ~600 m2/g, (KCC-1 M2) (112945‑52‑5)See page 94

14-6300 High Surface area Silica nanoparticles, small, particle size ~130-190 nm, surface area ~380 m2/g, (KCC-1 S1) (112945‑52‑5)See page 94

14-6310 High Surface area Silica nanoparticles, small, particle size ~40-50 nm, surface area ~520 m2/g, (KCC-1 S2) (112945‑52‑5)See page 94

NICKEL (Compounds) 28-121028-1210

a

(Acetonitrile)dichloronickel(II), 99% (18897‑44‑4) C2H3Cl2NNi; FW: 170.65; yellow pwdr. air sensitive, hygroscopic

NiCl

ClN C Me

1g 5g

28-000928-0009

aHAZcd

Allyl(cyclopentadienyl)nickel(II), min. 97% (12107‑46‑9) C8H10Ni; FW: 164.86; dark purple liq.; d. 1.31 air sensitive, moisture sensitive, pyrophoric

Ni

1g 5g

28-022528-0225

a

Bis(1,4-di-t-butyl-1,3-diazabutadienyl)nickel(II) Ni(DAD)2, min. 98% (99.999%-Ni) PURATREM C20H40N4Ni; FW: 395.25; Bis(1,4-di-t-butyl-1,3-diazabutadienyl)nickel(II) Ni(DAD)2, min. 98% (99.999%-Ni) PURATREM air sensitive Note: U.S. Patent Application No. 13/818,154. Product sold under, use subject to, terms and conditions of label license at www.strem.com/waynestate1

250mg 1g 5g

28-017828-0178

a

Chloro(4-cyanophenyl){(R)-1-[(S)-2-(bis(4-fluo-rophenyl)phosphinoferrocenyl]ethyl(di-t-butyl-phosphine)}nickel(II) (2049086‑37‑3) C39H42ClF2FeNNiP2; FW: 774.69; red-violet solid Note: Sold in collaboration with Solvias for research purposes only.

P

P(tBu)2

NiFe

CN

Me

FF

Cl

100mg500mg

Technical Note:1. See 28-0170 (page 51)

28-017228-0172

a

Chloro(4-cyanophenyl){(R)-1-[(S)-2-(dicyclo-hexylphosphino)ferrocenyl]ethyl (dicyclohex-ylphosphine)}nickel(II) (2049086‑35‑1) C43H60ClFeNNiP2; FW: 802.88; orange solid Note: Sold in collaboration with Solvias for research purposes only.

P

PCy2

NiFe

Cy

CyCl CN

Me 100mg 500mg

Technical Note:1. See 28-0170 (page 51)

N

Ni

N

N

N

tButBu

tBu tBu

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NICKEL (Compounds)28-017528-0175

a

Chloro(4-cyanophenyl){(R)-1-[(S)-2-(dicyclo-hexylphosphino)ferrocenyl]ethyl (diphenyl-phosphine)}nickel(II) (2049086‑36‑2) C43H48ClFeNNiP2; FW: 790.79; orange solid Note: Sold in collaboration with Solvias for research purposes only.

P

PPh2

NiFe

Cy

CyCl CN

Me 100mg 500mg

Technical Note:1. See 28-0170 (page 51)

28-017028-0170

a

Chloro(4-cyanophenyl){(R)-1-[(S)-2-(diphen-ylphosphino)ferrocenyl]ethyl(di-t-butyl)phosphine} nickel(II) (2049086‑34‑0) C39H44ClFeNNiP2; FW: 738.71; red-violet solid Note: Sold in collaboration with Solvias for research purposes only.

P

P(tBu)2

NiFe

Ph

PhCl CN

Me 100mg 500mg

Technical Notes:1. Versatile, air-stable, low cost nickel catalyst alternative to palladium for carbon-carbon and

carbonheteroatom cross-coupling reactions.2. Used to react substituted aryl and heteroaryl halides and tosylates with ammonia to produce diverse aryl and

heteroaryl amines1.3. Used in monoarylation experiments using commercially available ammonia gas, ammonium salts or

ammonia stock solutions2,3.4. Catalyzes the coupling of aryl chlorides with gaseous amines in the form of their hydrochloride salts3.

References:1. Org.Process Res. Dev., 2015, 19, 1936.2. Angew. Chem, Int. Ed., 2015, 54, 3773.3. Angew. Chem, Int. Ed., 2015, 54, 3768.

28-109528-1095

a

Chloro(cyclopentadienyl){1,3-bis[2-(di-phenylmethyl)-4,6-dimethyl-phenyl]1H-imidazolium}nickel(II) (1955555‑28‑8) C50H46ClN2Ni; FW: 769.06; pink purple pwdr.

100mg 500mg

Technical Note:1. Complexes of this type are pre-catalysts for Suzuki-

Miyaura2 and Buchwald-Hartwig3,4 cross-couplings, and for hydrosilylation4 and hydrothiolation5 of alkenes.

References:1. Dalton Trans. 2016, 45, 117722. Dalton Trans. 2010, 39, 81533. Organometallics 2013, 32, 62654. Organometallics 2005, 24, 3442-3447.5. Organometallics 2006, 25, 4462

28-051828-0518

a

Chloro(2-methylphenyl)[1,1’-bis(diphenylphos-phino)ferrocene]nickel (II), 98% (1501945‑23‑8) C41H35ClFeNiP2; FW: 739.66; yellow pwdr. air sensitive Fe

P

P

Ph

Ph Ph

Ni

Ph

Cl Me

100mg 500mg

Technical Note:1. Air-stable nickel precatalyst for the amination of aryl chlorides, sulfamates, mesylates and triflates.

Tech. Note (1)Ref. (1)

References:1. Org. Lett., 2014, 16, 220.

96-3660 Solvias Josiphos Nickel Catalyst Kit

See page 110

N N

MeMe

MeMe

PhPh

HPh

Ph H

Ni

Cl

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NITROGEN (Compounds)NITROGEN (Compounds)

07-206107-2061

a

(2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-(diphenyl-methyl)-N,3,3-trimethylbutanamide, 98%, (99% ee) (1421052‑39‑2) C27H38N4OS; FW: 466.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

Ph NN N

StBuMe

O HPh NH2

H

50mg

07-206007-2060

a

(2S)-2-[[[[(1S,2S)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-(diphenyl-methyl)-N,3,3-trimethylbutanamide, 98%, (99% ee) (1421697‑46‑2) C27H38N4OS; FW: 466.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

Ph NN N

StBuMe

O HPh

H

NH2

50mg

07-095507-0955

a

(2R)-2-[[[[(1S,2S)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) C21H34N4OS; FW: 390.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

Ph NN N

S

NH2

tBuMe

O H H

50mg

07-095607-0956

a

(2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) (479423‑21‑7) C21H34N4OS; FW: 390.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-098807-0988

a

N-[(1R,2R)-2-Aminocyclohex-yl]-N’-[3,5-bis(trifluoromethyl)phenyl]thiourea, 98%, (99% ee) (860994‑58‑7) C15H17F6N3S; FW: 385.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N CF3

CF3

S

N

H H

NH2

100mg

07-701807-7018

a

(2S)-2-Amino-3,3-dimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) (207121‑91‑3) C13H20N2O; FW: 220.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-701907-7019

a

(2R)-2-Amino-3,3-dimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) (268556‑62‑3) C13H20N2O; FW: 220.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

O

t-Bu

NH2

500mg

07-208107-2081

a

N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide, 95%, (99% ee) (167316‑28‑1) C15H15F3N2O2S; FW: 344.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-208007-2080

a

N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-1,1,1-tri-fluoromethanesulfonamide, 98%, (99% ee) (852212‑89‑6) C15H15F3N2O2S; FW: 344.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

Ph Ph

H2N N SH

CF3

O

O

100mg

07-803307-8033

a

(2S)-2-Amino-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) (947383‑62‑2) C14H22N2O; FW: 234.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

O

NH2 Me

PhtBu

100mg

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NITROGEN (Compounds)07-803407-8034

a

(2R)-2-Amino-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) C14H22N2O; FW: 234.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

t-BuO

NMeNH2

100mg

07-841007-8410

a

N,N’-(S)-[1,1’-Binaphthalene]-2,2’-diylbis[N’-[3,5-bis(trifluoromethyl)phenyl]thiourea], 95%, (99% ee) (914497‑25‑9) C38H22F12N4S2; FW: 826.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. NH

NH NH

S

NH

S

CF3

CF3

CF3

CF3

100mg

07-075007-0750

a

2,2’-Bipyrazine, 95% (10199‑00‑5) C8H6N4; FW: 158.16; light-brown solid air sensitive Note: Ligand for photocatalyst synthesis.

NN

NN

250mg 1g

Technical Notes:1. Ligand for the ruthenium- promoted catalytic water oxidation reaction.2. Ligand for the ruthenium promoted photocatalytic Diels-Alder cycloaddition.3. Ligand for the ruthenium photocatalyzed intermolecular [3+2] cycloaddition of cyclopropylamines with olefins.4. Ligand for the ruthenium mediated photocatalytic reaction for the preparation of N-arylindoles.5. Endoperoxide synthesis by photocatalytic aerobic [2+2+2] cycloadditions.6. [Ru(bpz)3](PF6)2 catalyzed anti-Markovnikov hydrothiolation of olefins with a variety of thiols.7. [Ru(bpz)3](PF6)2 catalyzed [3+2] photooxygenation of aryl cyclopropanes.8. [Ru(bpz)3](PF6)2 catalyzed intermolecular [3 + 2] annulation of cyclopropylanilines with alkynes.

Tech. Note (1)Ref. (1)

[Ru(bpz)3]2+

MeO

Me

+Me

MeO

MeMe

Tech. Note (2)Ref. (2)

[Ru(bpz)3](PF6)2N

X

R3

R1

H

R2

nR+ N

X

R2

n

R

R3R1

HTech. Note (3)Ref. (3)

[Ru(bpz)3](PF6)2NH

R1

OR

R2

N

R1

R2

OR

Tech. Note (4)Ref. (4)

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NITROGEN (Compounds)

[Ru(bpz)3](PF6)2

OMe

O

Ph

MeO

OO

O

PhH

H

O2

Tech. Note (5)Ref. (5)

[Ru(bpz)3](PF6)2+SR H RR

RSH Tech. Note (6)

Ref. (6)

[Ru(bpz)3](PF6)2

MeO

Ph

MeO

O O

PhO2

Tech. Note (7)Ref. (7)

[Ru(bpz)3](PF6)2+NH

NH

Tech. Note (8)Ref. (8)

References:1. J. Am. Chem. Soc., 2008, 130, 16462.2. J. Am. Chem. Soc., 2011, 133, 19350.3. Angew. Chem. Int. Ed.,., 2012, 51, 222.4. Angew. Chem. Int. Ed.,., 2012, 51, 9562.5. Org. Lett.,., 2012, 14, 1640.6. J. Org. Chem.,., 2013, 78, 2046.7. Tetrahedron, 2014, 70, 4270.8. Beilstein J. Org. Chem., , 2014, 10, 975.

07-704307-7043

a

2,2-Bis[(4R)-4-benzyl-2-oxazolin-2-yl]propane, 98%, (99% ee) (141362‑77‑8) C23H26N2O2; FW: 362.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N N

O O

Bn Bn

100mg

07-704407-7044

a

2,2-Bis[(4S)-4-benzyl-2-oxazolin-2-yl]propane, 98%, (99% ee) (176706‑98‑2) C23H26N2O2; FW: 362.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-048107-0481

a

3,8-Bis[3,5-bis(trifluorometh-yl)phenyl]-1,10-phenanthroline (1228032‑35‑6) C28H12F12N2; FW: 604.39; off-white pwdr. NN

F3C

F3C

CF3

CF3

100mg 500mg

07-2203 1,4-Bis(2-isocyanopropyl)piperazine (SnatchCat Metal Scavenger)

(51641‑96‑4)See page 44

07-632007-6320

a

N-[(1R,2R)-2-[Bis(phenylmethyl)amino]cy-clohexyl]-N’-[3,5-bis(trifluoromethyl)phenyl]thiourea, 98%, (99% ee) (1240466‑16‑3) C29H29F6N3S; FW: 565.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

S

NH

N

CF3

CF3

Bn Bn

50mg

07-0750(cont.)

2,2’-Bipyrazine, 95% (10199‑00‑5)

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NITROGEN (Compounds)

[Ru(bpz)3](PF6)2

OMe

O

Ph

MeO

OO

O

PhH

H

O2

Tech. Note (5)Ref. (5)

[Ru(bpz)3](PF6)2+SR H RR

RSH Tech. Note (6)

Ref. (6)

[Ru(bpz)3](PF6)2

MeO

Ph

MeO

O O

PhO2

Tech. Note (7)Ref. (7)

[Ru(bpz)3](PF6)2+NH

NH

Tech. Note (8)Ref. (8)

References:1. J. Am. Chem. Soc., 2008, 130, 16462.2. J. Am. Chem. Soc., 2011, 133, 19350.3. Angew. Chem. Int. Ed.,., 2012, 51, 222.4. Angew. Chem. Int. Ed.,., 2012, 51, 9562.5. Org. Lett.,., 2012, 14, 1640.6. J. Org. Chem.,., 2013, 78, 2046.7. Tetrahedron, 2014, 70, 4270.8. Beilstein J. Org. Chem., , 2014, 10, 975.

07-704307-7043

a

2,2-Bis[(4R)-4-benzyl-2-oxazolin-2-yl]propane, 98%, (99% ee) (141362‑77‑8) C23H26N2O2; FW: 362.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N N

O O

Bn Bn

100mg

07-704407-7044

a

2,2-Bis[(4S)-4-benzyl-2-oxazolin-2-yl]propane, 98%, (99% ee) (176706‑98‑2) C23H26N2O2; FW: 362.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-048107-0481

a

3,8-Bis[3,5-bis(trifluorometh-yl)phenyl]-1,10-phenanthroline (1228032‑35‑6) C28H12F12N2; FW: 604.39; off-white pwdr. NN

F3C

F3C

CF3

CF3

100mg 500mg

07-2203 1,4-Bis(2-isocyanopropyl)piperazine (SnatchCat Metal Scavenger)

(51641‑96‑4)See page 44

07-632007-6320

a

N-[(1R,2R)-2-[Bis(phenylmethyl)amino]cy-clohexyl]-N’-[3,5-bis(trifluoromethyl)phenyl]thiourea, 98%, (99% ee) (1240466‑16‑3) C29H29F6N3S; FW: 565.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

S

NH

N

CF3

CF3

Bn Bn

50mg

07-632107-6321

a

N-[(1S,2S)-2-[Bis(phenylmethyl)amino]cyclohexyl]-N’-[3,5-bis(trifluoromethyl)phenyl]thiourea, 98%, (99% ee) (1233369‑39‑5) C29H29F6N3S; FW: 565.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-705107-7051

a

2,6-Bis[(4R)-4-tert-butyloxazolin-2-yl]pyridine, 98%, (99% ee) (185346‑17‑2) C19H27N3O2; FW: 329.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NN

OO

Nt-Bu t-Bu

100mg

07-705007-7050

a

2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine, 98%, (99% ee) (118949‑63‑6) C19H27N3O2; FW: 329.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-713007-7130

a

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]-3-[1-(di-methylamino)-3-methylbutan-2-yl]thiourea, 98%, (99% ee) (1048692‑61‑0) C16H21F6N3S; FW: 401.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

CF3

CF3

N

H

S

N

H

Me2N

iPr

50mg

07-702907-7029

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6’-methoxycinchon-an-9-yl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1352957‑59‑5) C32H30F6N4O3; FW: 632.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

NH

HN

MeOO

O

HN

CF3

CF3

50mg

07-702807-7028

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6’-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1407166‑63‑5) C32H30F6N4O3; FW: 632.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

NH

HN

MeOO

O

HN

CF3

CF3

50mg

07-712807-7128

a

3-[[3,5-Bis(trifluoromethyl)phenyl]ami-no]-4-[[(1S,2S)-2-(dimethylamino)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 95%, (99% ee) (1263205‑96‑4) C20H21F6N3O2; FW: 449.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

O O

NN

H H

CF3

CF3

NMe2100mg

07-712907-7129

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1R,2R)-2-(dimethylamino)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1211565‑07‑9) C20H21F6N3O2; FW: 449.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-102507-1025

a

3-[[3,5-Bis(trifluoromethyl)phenyl]ami-no]-4-[[(1R,2R)-2-(dimethylamino)-1,2-di-phenylethyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1223105‑89‑2) C28H23F6N3O2; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

O O

NN

H H

NMe2

Ph

Ph

CF3

F3C

50mg

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NITROGEN (Compounds)07-851007-8510

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1R,2R)-2-(dipentylamino)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1411983‑40‑8) C28H37F6N3O2; FW: 561.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

O O

NHN

NH

CF3

CF3

50mg

07-851107-8511

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(dipentylamino)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1411983‑41‑9) C28H37F6N3O2; FW: 561.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-843607-8436

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6’-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, 95%, (99% ee) (1256245‑84‑7) C32H28F6N4O3; FW: 630.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

NH

HN

MeOO

O

HN

CF3

CF3

50mg

07-843507-8435

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6’-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1256245‑79‑0) C32H28F6N4O3; FW: 630.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

NH

HN

MeOO

O

HN

CF3

CF3

50mg

07-561007-5610

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1R,2R)-2-(1-piperidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98% (1211565‑11‑5) C23H25F6N3O2; FW: 489.50; orange pwdr. Note: Sold in collaboration with Daicel for research purposes only.

O

O

CF3

CF3

NH

N

N H

50mg

07-561107-5611

a

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee) (1346683‑42‑8) C22H23F6N3O2; FW: 475.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-063007-0630

a

(2R)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-3,3-dimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) C22H23F6N3OS; FW: 491.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

O

t-Bu

HN

HN

S

CF3

CF3

50mg

07-063107-0631

a

(2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-3,3-dimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee) (1490388‑03‑8) C22H23F6N3OS; FW: 491.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-630007-6300

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]thiourea, 95%, (99% ee) (949480‑57‑3) C18H14F6N2OS; FW: 420.4; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

HN

S

HN

CF3

F3C

HO

100mg

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NITROGEN (Compounds)07-841807-8418

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1R,2R)-2-(1,3-dihydro-2H-isoindol-2-yl)cyclohexyl]thiourea, 95%, (99% ee) (620960‑27‑2) C23H23F6N3S; FW: 487.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

S

NH

N

CF3

CF3

50mg

07-841907-8419

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1S,2S)-2-(1,3-dihydro-2H-isoindol-2-yl)cyclohexyl]thiourea, 98%, (99% ee) C23H23F6N3S; FW: 487.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-133607-1336

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1S,2S)-2-(dimethylamino)cyclohexyl]urea, 95%, (99% ee) (1221442‑12‑1) C17H21F6N3O; FW: 397.4; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N CF3

CF3

O

N

H HNMe2

100mg

07-133707-1337

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1R,2R)-2-(dimethylamino)cyclohexyl]urea, 98%, (99% ee) (820242‑14‑6) C17H21F6N3O; FW: 397.4; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-134507-1345

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1R,2R)-2-(dipentylamino)cyclohexyl]thiourea, 98%, (99% ee) C25H37F6N3S; FW: 525.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

CF3

CF3

N

H

S

N

HN

Bu Bu

50mg

07-134607-1346

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1S,2S)-2-(dipentylamino)cyclohexyl]thiourea, 98%, (99% ee) (1429516‑79‑9) C25H37F6N3S; FW: 525.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-631807-6318

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1R,2R)-2-(1-piperidinyl)cyclohexyl]thiourea, 98%, (99% ee) (1289514‑24‑4) C20H25F6N3S; FW: 453.50; light red xtl. Note: Sold in collaboration with Daicel for research purposes only.

NH

S

NH

N

CF3

CF3

50mg

07-631907-6319 N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(1S,2S)-2-(1-piperidinyl)

cyclohexyl]thiourea, 98%, (99% ee) (1244061‑69‑5) C20H25F6N3S; FW: 453.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

07-135007-1350

a

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl]thiourea, 98%, (99% ee) (1314743‑49‑1) C19H23F6N3S; FW: 439.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N CF3

CF3

S

N

H HN

50mg

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NITROGEN (Compounds)07-091207-0912

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(2S)-2-pyrrolidinylmethyl]thiourea, 98% (904928‑30‑9) C14H15F6N3S; FW: 371.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

CF3

CF3

N

H

S

N

H

N

H

100mg

07-717307-7173

a

2-[(4R)-4-tert-Butyl-4,5-dihydro-2-oxazolyl]-5-(trifluoromethyl)pyridine, 98%, (99% ee) (1428537‑19‑2) C13H15F3N2O; FW: 272.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NN

O

t-Bu

F3C 50mg

07-712407-7124

a

2-[(4S)-4-tert-Butyl-4,5-dihydro-2-oxazolyl]-5-(trifluoromethyl)pyridine, 98%, (99% ee) (1416819‑91‑4) C13H15F3N2O; FW: 272.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-631207-6312

a

N,N’-(1R,2R)-1,2-Cyclohexanediyl-bis[N’-[3,5-bis(trifluoromethyl)phenyl]thiourea], 98%, (99% ee) (743458‑79‑9) C24H20F12N4S2; FW: 656.6; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

NH

HNS

NH

S

CF3

CF3

CF3

CF3

100mg

07-181307-1813

a

2,6-Dichloro-1-fluoropyridinium triflate, 95% (130433‑68‑0) C6H3Cl2F4NO3S; FW: 316.06; white to light-yellow pwdr. air sensitive, moisture sensitive, (store cold)

500mg 2g

07-128007-1280

a

2-(2,4-Difluorophenyl)-5-methylpyridine, 95% (583052‑21‑5) C12H9F2N; FW: 205.20; white solid air sensitive Note: Ligand for photocatalyst synthesis.

N

F

F

Me 500mg 2g

07-192307-1923

aHAZ

4,7-Dimethoxy-1,10-phenanthroline, 98% (92149‑07‑0) C14H10N2O2; FW: 238.24; white to off-white pwdr.; m.p. 210-212°; d. 1.25 air sensitive Note: Ligand for photocatalyst synthesis.

NN

MeO OMe 250mg 1g

Technical Notes:1. Palladium-catalyzed synthesis of benzofurans and coumarins from phenols and olefins.2. Copper-catalyzed benzylic C(sp3)-H alkoxylation of heterocyclic compounds.3. Synthesis of amides via copper-catalyzed amidation of aryl halides using isocyanides.4. Iridium-catalyzed silylation of aryl C-H bonds.5. Palladium-catalyzed intramolecular cyclization of nitroalkenes: synthesis of thienopyrroles. 6. A Copper-catalyzed N-alkynylation route to 2-substitued N-alkynyl pyrroles and their cyclization into

pyrrolo[2,1-c]oxazin-1-ones

R'OH

O R2

R1

Pd(OAc)2, 1-10 phenanthroline Cu(OAc)2. NaOAc air, ClCH2CH2Cl, 110°C

O OR1

Tech. Note (1)Ref. (1)

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NITROGEN (Compounds)07-091207-0912

a

N-[3,5-Bis(trifluoromethyl)phenyl]-N’-[(2S)-2-pyrrolidinylmethyl]thiourea, 98% (904928‑30‑9) C14H15F6N3S; FW: 371.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

CF3

CF3

N

H

S

N

H

N

H

100mg

07-717307-7173

a

2-[(4R)-4-tert-Butyl-4,5-dihydro-2-oxazolyl]-5-(trifluoromethyl)pyridine, 98%, (99% ee) (1428537‑19‑2) C13H15F3N2O; FW: 272.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NN

O

t-Bu

F3C 50mg

07-712407-7124

a

2-[(4S)-4-tert-Butyl-4,5-dihydro-2-oxazolyl]-5-(trifluoromethyl)pyridine, 98%, (99% ee) (1416819‑91‑4) C13H15F3N2O; FW: 272.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-631207-6312

a

N,N’-(1R,2R)-1,2-Cyclohexanediyl-bis[N’-[3,5-bis(trifluoromethyl)phenyl]thiourea], 98%, (99% ee) (743458‑79‑9) C24H20F12N4S2; FW: 656.6; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

NH

HNS

NH

S

CF3

CF3

CF3

CF3

100mg

07-181307-1813

a

2,6-Dichloro-1-fluoropyridinium triflate, 95% (130433‑68‑0) C6H3Cl2F4NO3S; FW: 316.06; white to light-yellow pwdr. air sensitive, moisture sensitive, (store cold)

500mg 2g

07-128007-1280

a

2-(2,4-Difluorophenyl)-5-methylpyridine, 95% (583052‑21‑5) C12H9F2N; FW: 205.20; white solid air sensitive Note: Ligand for photocatalyst synthesis.

N

F

F

Me 500mg 2g

07-192307-1923

aHAZ

4,7-Dimethoxy-1,10-phenanthroline, 98% (92149‑07‑0) C14H10N2O2; FW: 238.24; white to off-white pwdr.; m.p. 210-212°; d. 1.25 air sensitive Note: Ligand for photocatalyst synthesis.

NN

MeO OMe 250mg 1g

Technical Notes:1. Palladium-catalyzed synthesis of benzofurans and coumarins from phenols and olefins.2. Copper-catalyzed benzylic C(sp3)-H alkoxylation of heterocyclic compounds.3. Synthesis of amides via copper-catalyzed amidation of aryl halides using isocyanides.4. Iridium-catalyzed silylation of aryl C-H bonds.5. Palladium-catalyzed intramolecular cyclization of nitroalkenes: synthesis of thienopyrroles. 6. A Copper-catalyzed N-alkynylation route to 2-substitued N-alkynyl pyrroles and their cyclization into

pyrrolo[2,1-c]oxazin-1-ones

R'OH

O R2

R1

Pd(OAc)2, 1-10 phenanthroline Cu(OAc)2. NaOAc air, ClCH2CH2Cl, 110°C

O OR1

Tech. Note (1)Ref. (1)

N

N

R4

OHR2

R1

R3

N

NR3

O

R4

R1

R2cat. CuBrn / ligand oxidant

Tech. Note (2)Ref. (2)

R NC + Ar X

O

Ar NR

H

Cu2O, Cs2CO3, ligand

80% aq. DMSO, 85°C

Tech. Note (3)Ref. (3)

X

HR n

[Ir(cod)OMe]2

"phenanthroline"

X = CH,N,O,Sn = 0,1

X

[Si]R

X

R'R

R' = OH, Br, I, aryl

Tech. Note (4)Ref. (4)

Tech. Note (5)Ref. (5)

N

R1

H

R2BrN

R1

R2

N

R1

O+

CuSO4.5H2O (10 mol%) ligand (20 mol%)

K2CO3 (200 mol%) toluene (0.5M), 135°C 14 h

O

R2

Tech. Note (6)Ref. (6)

References:1. Angew. Chem. Int. Ed., 2013, 52, 12669. 2. Organic & Biomolecular Chemistry, 2014, 12, 2528.3. Tetrahedron Letts., 2014, 55, 4981.4. J. Am. Chem. Soc., 2015, 137, 592.5. European Journal of Organic Chemistry, 2017, 2017(14), 1902 6. Synthesis, 2017, 49, 2544.

07-632607-6326 N-[(1S,2S)-2-(Dimethylamino)cyclohex-

yl]-N’-[(1R,2S)-2-hydroxy-1,2-diphenylethyl]thiourea, 98%, (99% ee) C23H31N3OS; FW: 397.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

NH

S PhPh

N OH

50mg

07-632507-6325

a

N-[(1S,2S)-2-(Dimethylamino)cyclohex-yl]-N’-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]thiourea, 98%, (99% ee) C23H31N3OS; FW: 397.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NH

NH

S PhPh

N OH

50mg

07-1923(cont.)

4,7-Dimethoxy-1,10-phenanthroline, 98% (92149‑07‑0)

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NITROGEN (Compounds)07-206307-2063

a

1-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-3-(perfluorophenyl)thiourea, 98%, (99% ee) C15H18F5N3S; FW: 367.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. N F

F

N

H H

F

F

FNMe2S

100mg

07-206407-2064

a

1-[(1S,2S)-2-(Dimethylamino)cyclohexyl]-3-(perfluorophenyl)thiourea, 98%, (99% ee) C15H18F5N3S; FW: 367.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-802007-8020

a

N,N’-[(1S,2S)-1,2-Diphenyl-1,2-ethanediyl]bis[N’-[3,5-bis(trifluoromethyl)phenyl]thiourea], 95%, (99% ee) (1416334‑72‑9) C32H22F12N4S2; FW: 754.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

07-082107-0821

a

N,N’-[(1R,2R)-1,2-Diphenyl-1,2-ethanediyl]bis[N’-[3,5-bis(trifluoromethyl)phenyl]thiourea], 98%, (99% ee) (1012051‑90‑9) C32H22F12N4S2; FW: 754.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

Ph Ph

N NNN

CF3

CF3F3C

F3C

H H

S S

HH

100mg

07-182807-1828

a

1-Fluoropyridinium triflate, 95% (107263‑95‑6) C6H5F4NO3S; FW: 247.17; white to pale-yellow pwdr. air sensitive, moisture sensitive, (store cold)

500mg 2g

07-183507-1835

a

1-Fluoro-2,4,6-trimethylpyridinium triflate (107264‑00‑6) C9H11F4NO3S; FW: 289.25; white to pale-yellow pwdr. air sensitive, moisture sensitive, (store cold)

500mg 2g

07-098407-0984

a

(2S)-N-[(1R,2S)-2-Hydroxy-1,2-diphenyleth-yl]-2-pyrrolidinecarboxamide, 98%, (99% ee) (529486‑23‑5) C19H22N2O2; FW: 310.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

HN

O

NH

PhPh

OH

100mg

07-098307-0983

a

(2S)-N-[(1S,2R)-2-Hydroxy-1,2-diphenyleth-yl]-2-pyrrolidinecarboxamide, 98%, (99% ee) (529486‑25‑7) C19H22N2O2; FW: 310.40; whie to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NPh

OHH

PhO

NH

100mg

07-104007-1040

a

2-[(4R)-4-Isobutyl-4,5-dihydro-2-oxaz-olyl]-5-(trifluoromethyl)pyridine, 98%, (99% ee) C13H15F3N2O; FW: 272.30; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

F3C

N

O

iBu

50mg

07-705807-7058

a

2-[(4R)-4-Isopropyl-4,5-dihydro-2-oxazolyl]-5-(tri-fluoromethyl)pyridine, 98%, (99% ee) C12H13F3N2O; FW: 258.20; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

NN

O

i-Pr

F3C 100mg

07-103507-1035

a

(3aR,3’aR,8aS,8’aS)-2,2’-(1-Methylethylidene)bis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole], 95%, (99% ee) (189623‑45‑8) C23H22N2O2; FW: 358.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N N

OO

Me Me 100mg

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NITROGEN (Compounds)07-103407-1034

a

(3aS,3’aS,8aR,8’aR)-2,2’-(1-Methylethylidene)bis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole], 98%, (99% ee) (175166‑51‑5) C23H22N2O2; FW: 358.40; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N N

OO

Me Me 100mg

07-710507-7105

a

(4S,4’S)-2,2’-[2-Phenyl-1-(phenylmethyl)ethylidene]bis[4-(1-methylethyl)-4,5-dihydrooxazole], 95%, (99% ee) (444575‑98‑8) C27H34N2O2; FW: 418.60; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. N N

OO

iPr iPr

Ph Ph 50mg

07-178007-1780

a

2-Phenylpyridine, 95% (1008‑89‑5) C11H9N; FW: 155.20; amber liquid; b.p. 268-270º; f.p. 230º; d. 1.086 air sensitive Note: Ligand for photocatalyst synthesis. N Ph

1g

07-090507-0905

a

3-[[(1S,2S)-2-(1-Piperidinyl)cyclohexyl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, 95%, (99% ee) (1312991‑08‑4) C22H26F3N3O2; FW: 421.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

N

O

ON

N

CF3

H

H

50mg

07-262507-2625

a

2-[4-(Trifluoromethyl)phenyl]pyridine, 95% (203065‑88‑7) C12H8F3N; FW: 223.19; white to yellow solid air sensitive Note: Ligand for photocatalyst synthesis.

N

F3C

1g

07-184007-1840

a

2-[(Trifluoromethyl)thio]-1,1-dioxide-1,2-benzisothiazol-3(2H)-one, 97% (1647073‑46‑8) C8H4F3NO3S2; FW: 283.25; white solid air sensitive, moisture sensitive

NS

O

SCF3

O O 250mg 1g

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OXYGEN (Compounds)OXYGEN (Compounds)

08-012508-0125

a

3,3’,5,5’-Azobenzene tetracarboxylic acid, TazbH4, 97% (365549‑33‑33) C16H10N2O8; FW: 358.26; yellow-orange pwdr. Note: Ligand for MOF Synthesis

HOOC COOH

NN

COOHHOOC 1g 5g

08-206508-2065

a

(R)-2,2’,3,3’-Tetrahydro-1,1’-spirobi[indene]-7,7’-diol, 99% (223259‑62‑9) C17H16O2; FW: 252.31; white solid Note: Sold in collaboration with Daicel for research purposes only.

OHOH

250mg 1g

98-800098-8000

a

Water, 99.999% (PURATREM), 98-0295, contained in 50 ml Swagelok® cylinder (96-1070) for CVD/ALD (7732‑18‑5) H2O; FW: 18.015; colorless liq.; m.p. 0; b.p. 100; d. 1.0

25g

PALLADIUM (Elemental Forms) 28-001528-0015

a

Nickel/palladium alloy nanoparticle on graphene (G-Ni33Pd67) black pwdr. Note: U.S. Patent Application 14/667,859.

25mg100mg

Technical Note:1. NiPd NPs are useful catalysts for the tandem dehydrogenation

of ammoniaborane and hydrogenation of R-NO2 or R-CN to R-NH2. NiPd nanoparticles also catalyze Suzuki-Miyaura and Heck cross-coupling reactions. The product is synthesized via the borane reduction of nickel and palladium salts in oleylamine, followed by dispersing the resulting mixture of Ni/Pd nanoparticles on graphene. The catalyst is 100% recyclable and shows no drop in catalytic activity after one month, when stored in air or argon at ambient temperatures.

References:1. Nano Research, 2013, 6, 10.2. ACS Catal., 2014, 4, 1777.

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PALLADIUM (Elemental Forms)OXYGEN (Compounds)

08-012508-0125

a

3,3’,5,5’-Azobenzene tetracarboxylic acid, TazbH4, 97% (365549‑33‑33) C16H10N2O8; FW: 358.26; yellow-orange pwdr. Note: Ligand for MOF Synthesis

HOOC COOH

NN

COOHHOOC 1g 5g

08-206508-2065

a

(R)-2,2’,3,3’-Tetrahydro-1,1’-spirobi[indene]-7,7’-diol, 99% (223259‑62‑9) C17H16O2; FW: 252.31; white solid Note: Sold in collaboration with Daicel for research purposes only.

OHOH

250mg 1g

98-800098-8000

a

Water, 99.999% (PURATREM), 98-0295, contained in 50 ml Swagelok® cylinder (96-1070) for CVD/ALD (7732‑18‑5) H2O; FW: 18.015; colorless liq.; m.p. 0; b.p. 100; d. 1.0

25g

PALLADIUM (Elemental Forms) 28-001528-0015

a

Nickel/palladium alloy nanoparticle on graphene (G-Ni33Pd67) black pwdr. Note: U.S. Patent Application 14/667,859.

25mg100mg

Technical Note:1. NiPd NPs are useful catalysts for the tandem dehydrogenation

of ammoniaborane and hydrogenation of R-NO2 or R-CN to R-NH2. NiPd nanoparticles also catalyze Suzuki-Miyaura and Heck cross-coupling reactions. The product is synthesized via the borane reduction of nickel and palladium salts in oleylamine, followed by dispersing the resulting mixture of Ni/Pd nanoparticles on graphene. The catalyst is 100% recyclable and shows no drop in catalytic activity after one month, when stored in air or argon at ambient temperatures.

References:1. Nano Research, 2013, 6, 10.2. ACS Catal., 2014, 4, 1777.

46-166046-1660

a

Palladium on carbon - 1 wt % loading, activated synthetic carbon pellet (7440‑05‑3) Pd; FW: 106.42; black pellet; SA: Pd 130 m2/g; P.Vol. 1.2 cm3/g

10g50g

Technical Notes:1. The enhanced dispersion of these Pd particles on the high

purity carbon support (in both powder and pellet forms) en-ables the catalysts’ operation under mild conditions (from RT to 60 °C) with higher selectivity and minimum unwanted side reactions.

One of the key differences of the Pd/C catalyst in pellet form (46-1660) is its more accessible surface area. This product has macroporosity (10 micron) and meso-porosity (6 nm) which makes carbon considerably lower in density (0.27 g/mL versus 0.5 -0.8 g/mL) and lighter than other carbon supports. This macroporosity allows palladium to be distributed throughout the carbon support instead of just on the outside. As a result, the metal surface area is much greater (130 m2/g vs 20 m2/g) and has a much smaller particle size (3.5 nm vs 40 nm).

46-161046-1610

a

Palladium on carbon - 1 wt % loading, activated synthetic carbon powder (7440‑05‑3) Pd; FW: 106.42; black pwdr.; SA: Pd 150 m2/g; P.Vol. 0.35 cm3/g

10g 50g

46-163046-1630

a

Palladium on carbon - 5 wt % loading, activated synthetic carbon powder (7440‑05‑3) Pd; black pwdr.; SA: Pd 70 m2/g; P.Vol. 0.35 cm3/g

5g 25g

PALLADIUM (Compounds) 46-070046-0700

a

Bis(acetonitrile)palladium(II) p-toluenesulfonate, 98% (114757‑66‑3) C18H20N2O6S2Pd; FW: 530.91; yellow pwdr. air sensitive, (store cold)

50mg 250mg

46-024146-0241

a

Bis{[2-(Diadamantylphosphi-no)-3-methoxy-2’,4’,6’-tri-i-pro-pyl-3’-(2,3,5,6-tetrafluoro-4-bu-tylphenyl)-1,1’-biphenyl]palladium(0)}1,5-cyclooctadiene, [AlPhos Palladium complex] (1805783‑51‑0) C112H146F8O2P2Pd2; FW: 1951.13; yellow-green solid Note: Patents: US 6,395,916, US 6,307,087

50mg 250mg

Technical Notes:1. Ligand for the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides.2. Ligand for the Palladium-Catalyzed Fluorination of Aryl Triflates and Bromides.

X

Z

Br

Z = S, O, NRX = N, CH

2 eq AgF0.5 eq KF

2% [(AlPhos-Pd)2(1,5-COD)]

TBME, 130°C, 14 hX

Z

FTech. Note (1)Ref. (1)

Tech. Note (2)Ref. (2)

References:1. Organometallics, 2015, 34, 47752. J. Am. Chem. Soc.,, 2015, 137, 13433

OMe

iPr

iPr

iPrAd2P

F

F

F

F

nBu

PdPd

MeO

iPr

iPr

iPrPAd2

F

F

F

F

nBu

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PALLADIUM (Compounds)46-030846-0308

a

Bis[(trimethylsilyl)methyl](1,5-cy-clooctadiene)palladium(II), 98% (225931‑80‑6) C16H34PdSi2; FW: 389.03; gray pwdr. air sensitive, (store cold)

Pd

SiMe3

SiMe3

250mg 1g

96-5506 Buchwald Palladacycle Precatalyst Kit 2b

(Methanesulfonato-2’-amino-1,1’-biphenyl-2-yl- Palladacycles Gen. 3)See page 105

46-034746-0347

a

Methanesulfonato(2-bis(3,5-di(tri-fluoromethyl)phenylphosphi-no)-3,6-dimethoxy-2’,6’-bis(di-methylamino)-1,1’-biphenyl )(2’-methylamino-1,1’-biphenyl-2-yl)palladium(II) [Palladacycle Gen. 4] (1810068‑35‑9) C48H44F12N3O5PPdS; FW: 1140.32; yellow to orange solid Note: Patents: PCT/US2013/030779, US Serial No. 13/799620

PdN OMs

Me2N PR2

(H)Me

Me2N

OMe

OMe

R =

CF3

CF3

100mg500mg

46-093546-0935

a

Methanesulfonato{N-[2-(di-1-adamantylphosphino)phenyl]morpholine}(2’-amino-1,1’-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [Mor-Dalphos Palladacycle Gen. 3] C43H55N2O4PPdS; FW: 833.37; Beige to brown solid Note: Patents: PCT/US2013/030779, US Serial No. 13/799620

PdH2N OMs

NO PAd2

250mg 1g

Technical Note:1. Palladium catalyst for ammonia arylation2. Palladium catalyst for multicomponent one-pot synthesis of indoles.3. Palladium catalyst for primary aliphatic amination of aryl mesylates.4. Palladium catalyst for ketone mono-α-arylation of aryl mesylates.

RX

+ NH3 RNH2

X = Cl or OTsR= electron-donatingor withdrawing group

Tech. Note (1)Ref. (1)

X

Cl

+ H2NR1

NR1

R2O

Me R2+

MorDalPhos/Pd (cat.)

Cs2CO3

toluene, 90o

Tech. Note (2)Ref. (2)

OMs+

MorDalPhos/Pd (cat.)R R

HN

R' R''

NR'

tBuOH/1.4-dioxane K3PO4 110°, 16-20 h

R"Tech. Note (3)Ref. (3)

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PALLADIUM (Compounds)46-030846-0308

a

Bis[(trimethylsilyl)methyl](1,5-cy-clooctadiene)palladium(II), 98% (225931‑80‑6) C16H34PdSi2; FW: 389.03; gray pwdr. air sensitive, (store cold)

Pd

SiMe3

SiMe3

250mg 1g

96-5506 Buchwald Palladacycle Precatalyst Kit 2b

(Methanesulfonato-2’-amino-1,1’-biphenyl-2-yl- Palladacycles Gen. 3)See page 105

46-034746-0347

a

Methanesulfonato(2-bis(3,5-di(tri-fluoromethyl)phenylphosphi-no)-3,6-dimethoxy-2’,6’-bis(di-methylamino)-1,1’-biphenyl )(2’-methylamino-1,1’-biphenyl-2-yl)palladium(II) [Palladacycle Gen. 4] (1810068‑35‑9) C48H44F12N3O5PPdS; FW: 1140.32; yellow to orange solid Note: Patents: PCT/US2013/030779, US Serial No. 13/799620

PdN OMs

Me2N PR2

(H)Me

Me2N

OMe

OMe

R =

CF3

CF3

100mg500mg

46-093546-0935

a

Methanesulfonato{N-[2-(di-1-adamantylphosphino)phenyl]morpholine}(2’-amino-1,1’-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [Mor-Dalphos Palladacycle Gen. 3] C43H55N2O4PPdS; FW: 833.37; Beige to brown solid Note: Patents: PCT/US2013/030779, US Serial No. 13/799620

PdH2N OMs

NO PAd2

250mg 1g

Technical Note:1. Palladium catalyst for ammonia arylation2. Palladium catalyst for multicomponent one-pot synthesis of indoles.3. Palladium catalyst for primary aliphatic amination of aryl mesylates.4. Palladium catalyst for ketone mono-α-arylation of aryl mesylates.

RX

+ NH3 RNH2

X = Cl or OTsR= electron-donatingor withdrawing group

Tech. Note (1)Ref. (1)

X

Cl

+ H2NR1

NR1

R2O

Me R2+

MorDalPhos/Pd (cat.)

Cs2CO3

toluene, 90o

Tech. Note (2)Ref. (2)

OMs+

MorDalPhos/Pd (cat.)R R

HN

R' R''

NR'

tBuOH/1.4-dioxane K3PO4 110°, 16-20 h

R"Tech. Note (3)Ref. (3)

OMs+

MorDalPhos/Pd (cat.)R R

O

R"R'

O

R"R'

tBuOH/1.4-dioxane K3PO4 or K2CO3

90°C, or 110°C, 16-40 h

Tech. Note (4)Ref. (3)

References:1. Angew. Int. Ed., 2010, 49, 4071.2. Angew. Int. Ed., 2013, 52, 7242.3. Adv. Synth. Catal., 2015, 357, 100.

46-094046-0940

a

Methanesulfonato{N-[2-(di-1-adamantylphosphi-no)phenyl]morpholine}(2’-methylamino-1,1’-bi-phenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% MorDalphos Palladacycle Gen. 4 C44H57N2O4PPdS; FW: 847.39; off-white to gray solid Note: Patents: PCT/US2013/030779, US Serial No. 13/799620.

PdMeHN OMs

N

O PAd2

250mg 1g

Technical Note:1. See 46-0935 (page 64)

46-098046-0980

a

Methanesulfonato(2-dicyclohexylphosphi-no-1,1’-biphenyl)(2’-methylamino-1,1-biphe-nyl-2-yl)]palladium(II) dichloromethane adduct, min. 98% CyJohnphos Palladacycle Gen. 4 C38H46NO3PPdS; FW: 734.24; light brown solid Note: Patents: PCT/US2013/030779, US Serial No. 13/799620

PdMeHN OMs

Cy2P

250mg 1g

46-0935(cont.)

Methanesulfonato{N-[2-(di-1-adamantylphosphino)phenyl]morpholine}(2’-amino-1,1’-biphe-nyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [Mor-Dalphos Palladacycle Gen. 3]

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PHOSPHORUS (Compounds)PHOSPHORUS (Compounds)

15-196015-1960

a

4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydroben-zo[d][1,3]oxaphosphole, 98+% rac-AntPhos (1268693‑24‑8) C25H23O3P; FW: 370.42; pale yellow pwdr. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

P

O

tBu

25mg 100mg 500mg

Technical Notes:1. Ligand/palladium catalyst for general Miyaura borylation reactions.2. Ligand/palladium catalyst for general and sterically demanding Suzuki-Miyaura cross-coupling reactions.3. Ligand/palladium catalyst for aryl-alkyl Suzuki-Miyaura cross-coupling reactions.4. Ligand/nickel catalyst for intramolecular reductive cyclization.5. Ligand/palladium catalyst for Dearomative cyclization.

BrR

+O

BO

BO

O Bedford Pd precursor Ligand

KOAc, DMAc

RB

O

O Tech. Note (1)Ref. (1)

BrR

+ BHO Pd(OAc)2

Ligand

K3PO4, Dioxane

RHO

R R Tech. Note (2)Ref. (2)

BrR

+ BHO Pd(OAc)2

Ligand

K3PO4, toluene

RHO

nn

Tech. Note (3)Ref. (3)

OR'

O

R''n

Ni(COD)2Ligand

Et3SiHO

R'

HOSiEt3

R''n

O

R'

OH

R''n

Tech. Note (4)Ref. (4)

HO

R X [Pd]Ligand

K2CO3, toluene O

R

Tech. Note (5)Ref. (5,6)

References:1. Org. Lett., 2011,13,1366.2. Chem. Eur. J., 2013,19,2261.3. Org.Chem. Front., 2014,1, 225.4. Angew. Chem. Int. Ed., 2015, 54, 2520.5. Angew. Chem. Int. Ed., 2015, 54, 3033.6. Tetrahedron, 2016, 72, 1782.

15-196315-1963

a

(R)-4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphole,98+% (>99% ee) [(R)-AntPhos] (1456816‑37‑7) C25H23O3P; FW: 370.42; light-yello xtl. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

P

O

tBu

25mg 100mg 500mg

Technical Note:1. See 15-1960 (page 66)

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PHOSPHORUS (Compounds)PHOSPHORUS (Compounds)

15-196015-1960

a

4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydroben-zo[d][1,3]oxaphosphole, 98+% rac-AntPhos (1268693‑24‑8) C25H23O3P; FW: 370.42; pale yellow pwdr. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

P

O

tBu

25mg 100mg 500mg

Technical Notes:1. Ligand/palladium catalyst for general Miyaura borylation reactions.2. Ligand/palladium catalyst for general and sterically demanding Suzuki-Miyaura cross-coupling reactions.3. Ligand/palladium catalyst for aryl-alkyl Suzuki-Miyaura cross-coupling reactions.4. Ligand/nickel catalyst for intramolecular reductive cyclization.5. Ligand/palladium catalyst for Dearomative cyclization.

BrR

+O

BO

BO

O Bedford Pd precursor Ligand

KOAc, DMAc

RB

O

O Tech. Note (1)Ref. (1)

BrR

+ BHO Pd(OAc)2

Ligand

K3PO4, Dioxane

RHO

R R Tech. Note (2)Ref. (2)

BrR

+ BHO Pd(OAc)2

Ligand

K3PO4, toluene

RHO

nn

Tech. Note (3)Ref. (3)

OR'

O

R''n

Ni(COD)2Ligand

Et3SiHO

R'

HOSiEt3

R''n

O

R'

OH

R''n

Tech. Note (4)Ref. (4)

HO

R X [Pd]Ligand

K2CO3, toluene O

R

Tech. Note (5)Ref. (5,6)

References:1. Org. Lett., 2011,13,1366.2. Chem. Eur. J., 2013,19,2261.3. Org.Chem. Front., 2014,1, 225.4. Angew. Chem. Int. Ed., 2015, 54, 2520.5. Angew. Chem. Int. Ed., 2015, 54, 3033.6. Tetrahedron, 2016, 72, 1782.

15-196315-1963

a

(R)-4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphole,98+% (>99% ee) [(R)-AntPhos] (1456816‑37‑7) C25H23O3P; FW: 370.42; light-yello xtl. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

P

O

tBu

25mg 100mg 500mg

Technical Note:1. See 15-1960 (page 66)

15-196715-1967

a

(S)-4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphole,99+% (>99% ee) [(S)-AntPhos] (1807740‑34‑6) C25H23O3P; FW: 370.42; light yellow xtl. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

25mg 100mg 500mg

Technical Note:1. Ligand for the enantioselective nickel-catalyzed intramolecular reductive cyclization of alkynones.

Tech. Note (1)Ref. (1)

References:1. Angew. Chem. Int. Ed., 2015, 54, 2520.

96-0650 BI-DIME Ligand Kit

See page 102 15-029315-0293

a

(11aR)-3,7-Bis([1,1’-biphenyl]-4-yl)-10,11,12,13-tetrahydro-5-hydroxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1297613‑77‑4) C41H31O4P; FW: 618.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO P

OOH

25mg

15-029415-0294

a

(11aS)-3,7-Bis([1,1’-biphenyl]-4-yl)-10,11,12,13-tetrahydro-5-hydroxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1297613‑77‑4) C41H31O4P; FW: 618.67; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg

15-136615-1366

a

(11bR)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (791616‑62‑1) C36H17F12O4P; FW: 772.5; white to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

OOH

CF3

CF3

CF3

CF3

100mg

15-136715-1367

a

(11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (878111‑17‑2) C36H17F12O4P; FW: 772.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

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PHOSPHORUS (Compounds)15-137615-1376

a

(11bR)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-8,9,10,11,12,13,14,15-octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphos-phepin, 98%, (99% ee) (1011465‑24‑9) C36H25F12O4P; FW: 780.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

CF3

CF3

CF3

CF3

PO

OH

25mg 100mg

15-137715-1377

a

(11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-8,9,10,11,12,13,14,15-octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxa-phosphepin, 98%, (99% ee) C36H25F12O4P; FW: 780.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

15-027615-0276

a

(11aR)-3,7-Bis(4-chlorophenyl)-10,11,12,13-tetra-hydro-5-hydroxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) C29H21Cl2O4P; FW: 535.36; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

Cl

Cl

OO

POOH

50mg

15-027515-0275

a

(11aS)-3,7-Bis(4-chlorophenyl)-10,11,12,13-tetrahydro-5-hydroxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1258327‑05‑7) C29H21Cl2O4P; FW: 535.36; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

15-328015-3280

a

(11bR)-2,6-Bis[4-(1,1-dimethylethyl)phenyl]-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (861909‑30‑0) C40H37O4P; FW: 612.71; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

t-Bu

t-Bu

PO

OH

50mg

15-033915-0339

a

(11aR)-3,7-Bis((4-(1,1-dimethylethyl)phenyl)-10,11,12,13-tetrahydro-5-hydroxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) C37H39O4P; FW: 578.7; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO P

O

OH

tBu

tBu

25mg

15-033815-0338

a

(11aS)-3,7-Bis((4-(1,1-dimethylethyl)phenyl)-10,11,12,13-tetrahydro-5-hy-droxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) C37H39O4P; FW: 578.70; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg

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PHOSPHORUS (Compounds)15-136815-1368

a

(11bR)-2,6-Bis(3,5-dimethylphenyl)-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphos-phepin, 98%, (99% ee) (861909‑53‑7) C36H29O4P; FW: 556.6; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

OOH

CH3

CH3

CH3

CH3

100mg

15-136915-1369

a

(11bS)-2,6-Bis(3,5-dimethylphenyl)-4-hydroxy-4-oxide-di-naphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1170736‑59‑0) C36H29O4P; FW: 556.6; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

15-137315-1373

a

(11bR)-2,6-Bis(3,5-dimethylphenyl)-8,9,10,11,12,13,14,15-octahydro-4-hydroxy-4-ox-ide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1065214‑95‑0) C36H37O4P; FW: 564.7; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

CH3

CH3

CH3

CH3

PO

OH

25mg 100mg

15-137415-1374

a

(11bS)-2,6-Bis(3,5-dimethylphenyl)-8,9,10,11,12,13,14,15-octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) C36H37O4P; FW: 564.7; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

15-037415-0374

a

Bis(pentafluorophenyl)phenylphosphine, 97% (5074‑71‑5) C18H5F10P; FW: 442.20; white pwdr.; m.p. 59-61°; b.p. 105°C/0.3mm; f.p. >110°C air sensitive P

F

F F

F

F

F

F F

F

F

250mg 1g

15-027715-0277

a

(11aR)-3,7-Bis(1-pyrenyl)-10,11,12,13-tetrahydro-5-hy-droxy-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) C49H31O4P; FW: 714.7; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

O POOH

25mg

15-027815-0278

a

(11aS)-3,7-Bis(1-pyrenyl)-10,11,12,13-tetrahydro-5-hydroxy-di-indeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) C49H31O4P; FW: 714.7; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg

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PHOSPHORUS (Compounds)15-063815-0638

a

Bis(p-sulfonatophenyl)phenylphos-phine dihydrate dipotassium salt, 97% (308103‑66‑4) C18H13K2O6PS2; FW: 498.60(534.63); white pwdr.; m.p. 98-102° air sensitive

PhP

SSO

O

O

O

O--O K+K+2H2O

100mg 500mg

15-139515-1395

a

(R)-3,3’-Bis2,4,6-triisopropyl-phenyl)-5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-binaph-thyl-2,2’-diyl Hydrogenphosphate, 98%, (99% ee) (929294‑27‑9) C50H65O4P; FW: 761; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

P(O)OH

i-Pr

i-Pr

i-Pr

i-Pr

i-Pr i-Pr

25mg 100mg

15-139415-1394

a

(S)-3,3’-Bis2,4,6-triisopropylphenyl)-5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-binaphthyl-2,2’-diyl Hydrogenphosphate, 98%, (99% ee) (878111‑20‑7) C50H65O4P; FW: 761; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

96-5495 Buchwald Biaryl Phosphine Ligand Mini Kit 3 for Aromatic Carbon-Heteroatom

Bond Formation, Suzuki Coupling and Negishi Cross-couplingSee page 103

15-620515-6205

a

3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% rac-BI-DIME (1246888‑90‑3) C19H23O3P; FW: 330.36; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038

P

O

MeO OMetBu

25mg 100mg 500mg

Technical Notes:1. Ligand/palladium catalyst for general and sterically demanding Suzuki-Miyaura cross-coupling reactions2. Ligand/palladium catalyst for sterically demanding Buchwald-Hartwig amination3. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions.4. Ligand/nickel catalyst for asymmetric intramolecular reductive cyclization5. Ligand/rhodium catalyst for asymmetric hydroboration

BrR + B

HO Pd(OAc)2 Ligand

K3PO4, DioxaneR

HO

R R Tech. Note (1)Ref. (1,2)

BrR

+ HN

Pd(OAc)2 Ligand

K3PO4, tolueneR"

R'N

R"

R'R Tech. Note (2)Ref. (3)

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (3)Ref. (4,5,6)

OR'

OR''n

Ni(COD)2Ligand

Et3SiHO

R'

HOSiEt3

R''n

O

R'

OHR''n

Tech. Note (4)Ref. (7,8)

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PHOSPHORUS (Compounds)15-063815-0638

a

Bis(p-sulfonatophenyl)phenylphos-phine dihydrate dipotassium salt, 97% (308103‑66‑4) C18H13K2O6PS2; FW: 498.60(534.63); white pwdr.; m.p. 98-102° air sensitive

PhP

SSO

O

O

O

O--O K+K+2H2O

100mg 500mg

15-139515-1395

a

(R)-3,3’-Bis2,4,6-triisopropyl-phenyl)-5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-binaph-thyl-2,2’-diyl Hydrogenphosphate, 98%, (99% ee) (929294‑27‑9) C50H65O4P; FW: 761; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

P(O)OH

i-Pr

i-Pr

i-Pr

i-Pr

i-Pr i-Pr

25mg 100mg

15-139415-1394

a

(S)-3,3’-Bis2,4,6-triisopropylphenyl)-5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-binaphthyl-2,2’-diyl Hydrogenphosphate, 98%, (99% ee) (878111‑20‑7) C50H65O4P; FW: 761; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

96-5495 Buchwald Biaryl Phosphine Ligand Mini Kit 3 for Aromatic Carbon-Heteroatom

Bond Formation, Suzuki Coupling and Negishi Cross-couplingSee page 103

15-620515-6205

a

3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% rac-BI-DIME (1246888‑90‑3) C19H23O3P; FW: 330.36; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038

P

O

MeO OMetBu

25mg 100mg 500mg

Technical Notes:1. Ligand/palladium catalyst for general and sterically demanding Suzuki-Miyaura cross-coupling reactions2. Ligand/palladium catalyst for sterically demanding Buchwald-Hartwig amination3. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions.4. Ligand/nickel catalyst for asymmetric intramolecular reductive cyclization5. Ligand/rhodium catalyst for asymmetric hydroboration

BrR + B

HO Pd(OAc)2 Ligand

K3PO4, DioxaneR

HO

R R Tech. Note (1)Ref. (1,2)

BrR

+ HN

Pd(OAc)2 Ligand

K3PO4, tolueneR"

R'N

R"

R'R Tech. Note (2)Ref. (3)

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (3)Ref. (4,5,6)

OR'

OR''n

Ni(COD)2Ligand

Et3SiHO

R'

HOSiEt3

R''n

O

R'

OHR''n

Tech. Note (4)Ref. (7,8)

HN

O

(Bpin)2B

HN

O

OO

R R

Rh(NBD)2BF4

DABCO+

ligandTech. Note (5)Ref. (9)

References:1. Angew. Chem., Int. Ed. 2010, 49, 5879-5883 2. Chem. Eur. J. 2013, 19, 2261-22653. Adv. Syn. Cat. 2011, 353, 533-5374. Org. Lett. 2012, 14 , 2258–22615. J. Am. Chem. Soc., 2014, 136, 570–5736. Angew. Chem., Int. Ed. 2015, 54, 7144-71487. Angew. Chem., Int. Ed. 2015, 54, 2520 -25248. Org. Chem. Front. 2015, 2, 1322-13259. J. Am. Chem. Soc. 2015, 137, 6746-6749

15-621115-6211

a

(R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (R)-BI-DIME (1373432‑03‑7) C19H23O3P; FW: 330.36; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

P

O

MeO OMetBu

25mg 100mg 500mg

Technical Notes:1. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions.2. Ligand/nickel catalyst for asymmetric intramolecular reductive cyclization3. Ligand/rhodium catalyst for asymmetric hydroboration

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (1)Ref. (1,2,3)

OR'

OR''n

Ni(COD)2Ligand

Et3SiHO

R'

HOSiEt3

R''n

O

R'

OHR''n

Tech. Note (2)Ref. (4,5)

HN

O

(Bpin)2B

HN

O

OO

R R

Rh(NBD)2BF4

DABCO+

ligandTech. Note (3)Ref. (6)

References:1. Org. Lett. 2012, 14 , 2258–22612. J. Am. Chem. Soc., 2014, 136, 570–5733. Angew. Chem., Int. Ed. 2015, 54, 7144-71484. Angew. Chem., Int. Ed. 2015, 54, 2520 -25245. Org. Chem. Front. 2015, 2, 1322-13256. J. Am. Chem. Soc. 2015, 137, 6746-6749

15-6205(cont.)

3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% rac-BI-DIME (1246888‑90‑3)

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PHOSPHORUS (Compounds)15-621015-6210 (S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]

oxaphosphole, min. 97% (S)-BI-DIME (1373432‑09‑7) C19H23O3P; FW: 330.36; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

25mg 100mg 500mg

Technical Note:1. See 15-6211 (page 71)

15-622515-6225

a

(2R,3R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-methyl-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% (R,R)-Me-BI-DIME (1477517‑18‑2) C20H25O3P; FW: 344.38; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

P

O

MeO OMetBu

Me

25mg 100mg 500mg

Technical Note:1. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (1)Ref. (1,2,3)

References:1. Org. Lett. 2012, 14 , 2258–22612. J. Am. Chem. Soc. 2014, 136, 570-5733. Angew. Chem., Int. Ed. 2015, 54, 7144-7148

15-622015-6220

a

(2S,3S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-methyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (S,S)-Me-BI-DIME (1373432‑11‑1) C20H25O3P; FW: 344.38; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

25mg 100mg 500mg

Technical Note:1. See 15-6225 (page 72)

15-623515-6235

a

(2R,3R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-i-propyl-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% (R,R)-iPr-BI-DIME (1477517‑19‑3) C22H29O3P; FW: 372.44; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

P

O

MeO OMetBu

iPr

25mg 100mg 500mg

Technical Note:1. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (1)Ref. (1,2,3)

References:1. Org. Lett. 2012, 14 , 2258–22612. J. Am. Chem. Soc. 2014, 136, 570-5733. Angew. Chem., Int. Ed. 2015, 54, 7144-7148

15-623015-6230

a

(2S,3S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-i-propyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (S,S)-iPr-BI-DIME (1477517‑21‑7) C22H29O3P; FW: 372.44; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

25mg 100mg 500mg

Technical Note:1. See 15-6235 (page 72)

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PHOSPHORUS (Compounds)15-621015-6210 (S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]

oxaphosphole, min. 97% (S)-BI-DIME (1373432‑09‑7) C19H23O3P; FW: 330.36; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

25mg 100mg 500mg

Technical Note:1. See 15-6211 (page 71)

15-622515-6225

a

(2R,3R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-methyl-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% (R,R)-Me-BI-DIME (1477517‑18‑2) C20H25O3P; FW: 344.38; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

P

O

MeO OMetBu

Me

25mg 100mg 500mg

Technical Note:1. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (1)Ref. (1,2,3)

References:1. Org. Lett. 2012, 14 , 2258–22612. J. Am. Chem. Soc. 2014, 136, 570-5733. Angew. Chem., Int. Ed. 2015, 54, 7144-7148

15-622015-6220

a

(2S,3S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-methyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (S,S)-Me-BI-DIME (1373432‑11‑1) C20H25O3P; FW: 344.38; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

25mg 100mg 500mg

Technical Note:1. See 15-6225 (page 72)

15-623515-6235

a

(2R,3R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-i-propyl-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% (R,R)-iPr-BI-DIME (1477517‑19‑3) C22H29O3P; FW: 372.44; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

P

O

MeO OMetBu

iPr

25mg 100mg 500mg

Technical Note:1. Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions

Br + BHO

Pd(OAc)2 Ligand

K3PO4, DioxaneHO

RR'

R"

R'

R"

R

Tech. Note (1)Ref. (1,2,3)

References:1. Org. Lett. 2012, 14 , 2258–22612. J. Am. Chem. Soc. 2014, 136, 570-5733. Angew. Chem., Int. Ed. 2015, 54, 7144-7148

15-623015-6230

a

(2S,3S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-i-propyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (S,S)-iPr-BI-DIME (1477517‑21‑7) C22H29O3P; FW: 372.44; light-yellow xtl. Note: Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038.

25mg 100mg 500mg

Technical Note:1. See 15-6235 (page 72)

15-101115-1011

a

Cyclohexyldi-t-butylphosphine, 98% (10wt% in hexanes) (436865‑11‑1) C14H29P; FW: 228.36; colorless liq. air sensitive

5g 25g

15-197015-1970

a

(2R,2’R,3R,3’R)-4,4’-Di(anthracen-9-yl)-3,3’-di-t-butyl-2,2’,3,3’-tetrahydro-2,2’-bibenzo[d][1,3]oxaphosphole, min 98% (>90% ee), [(2R,2’R,3R,3’R)-WingPhos] (1884680‑45‑8) C50H44O2P2; FW: 738.83; light yello pwdr. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

P

O

H

P

O

H

tBu

tBu

25mg 100mg 500mg

Technical Note:1. Ligand for rhodium-catalyzed enantioselective addition of arylboroxines to simple aryl ketones.

[Rh], LigandCsF, MgBr2, MTBE

Ar R

O+ (Ar'BO)3

Ar Ar'

HO R Tech. Note (1)Ref. (1)

References:1. Angew. Chem.Int Ed., 2016, 55, 4527.

15-197515-1975

a

(2S,2’S,3S,3’S)-4,4’-Di(anthracen-9-yl)-3,3’-di-t-butyl-2,2’,3,3’-tet-rahydro-2,2’-bibenzo[d][1,3]oxaphosphole, min 98%, (>99% ee), [(2S,2’S,3S,3’S)-WingPhos] (1435940‑19‑4) C50H44O2P2; FW: 738.83; light yellow pwdr. air sensitive, (store cold) Note: Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390.

25mg 100mg 500mg

Technical Notes:1. Ligand/Rhodium catalyst for asymmetric hydrogenation.2. Ligand/Rhodium catalyst for asymmetric arylboronic reagents addition to aryl ketones.

Rh[(nbd)(L)]BF4

DCM, H2

NHAcR

NHAcR

Tech. Note (1)Ref. (1)

Ar

O

R

[Rh(C2H4)2Cl]2, L

CsF, MgBr2, MTBE(Ar'BO)3+

Ar Ar'

HO R Tech. Note (2)Ref. (2)

References:1. Angew. Chem.Int.Ed., 2013, 52, 4235.2. Angew. Chem.Int Ed., 2016, 55, 4527.

15-033415-0334

a

(11aR)-3,7-Di-9-anthracenyl-10,11,12,13-tetra-hydro-5-hydroxy-5-oxide-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1345628‑08‑1) C45H31O4P; FW: 666.71; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

O PO

OH

25mg

15-033515-0335

a

(11aS)-3,7-Di-9-anthracenyl-10,11,12,13-tetrahydro-5-hydroxy-5-oxide-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1393527‑23‑5) C45H31O4P; FW: 666.71; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg

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PHOSPHORUS (Compounds)15-087015-0870

a

(11bS)-N-((R)-2,3-dihydro-1H-inden-1-yl)-N-(Di-n-butyl methyl)dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin-4-amine (2019254‑27‑2) C38H40NO2P; FW: 573.7 Note: Patent: UK1710941.4

OP

ON

nBunBu

15-172015-1720

a

1-(2-Di-t-butylphosphinophenyl)-3,5-diphe-nyl-1H-pyrazole, 98% (628333‑86‑8) C29H33N2P; FW: 440.56; white xtl.; m.p. 138-142° air sensitive

P(tBu)2

NN

Ph

Ph

250mg 1g

15-083715-0837

a

(11bS)-2,6-Di-9-phenanthrenyl-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphos-phepin, 98% (1043567‑32‑3) C48H29O4P; FW: 700.71; red brown pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

OOH

50mg

15-138015-1380

a

Diphenyl[4-(N,N-dimethylamino)phenyl]phosphine, min. 95% (739‑58‑2) C20H20NP; FW: 305.35; white solid; m.p. 151-154° air sensitive

NPMe

Me

Ph

Ph

1g 5g

15-086015-0860

a

(11bS)-N-(Diphenylmethyl)-N-isopropyldinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin-4-amine (1637749‑69‑9) C36H30NO2P; FW: 539.6 Note: Patents: US20160074852, EP2986375

O

OP N

iPr

Ph

Ph

15-036415-0364

a

(11bR)-2,6-Di-1-pyrenyl-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) C52H31O4P; FW: 748.80; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

O

OH

50mg

15-036515-0365

a

(11bS)-2,6-Di-1-pyrenyl-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) C52H31O4P; FW: 748.8; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

Technical Note:1. See 15-0364 (page 74)

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PHOSPHORUS (Compounds)15-030915-0309

a

(11bR)-4-Hydroxy-2,6-bis(4-methoxyphenyl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (695162‑88‑0) C34H25O6P; FW: 560.50; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

POOH

OMe

OMe

50mg

15-030815-0308

a

(11bS)-4-Hydroxy-2,6-bis(4-methoxyphenyl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1374030‑19‑9) C34H25O6P; FW: 560.5; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

Technical Note:1. See 15-0309 (page 75)

15-031715-0317

a

(11bS)-4-Hydroxy-2,6-bis([1,1’:3’,1’’-terphenyl]-5’-yl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1496637‑05‑8) C56H37O4P; FW: 804.90; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

O

OH

Ph

Ph

Ph

Ph

50mg

15-139215-1392

a

(11bR)-4-Hydroxy-2,6-bis[4-(trifluoromethyl)phenyl]-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 95%, (99% ee) (791616‑59‑6) C34H19F6O4P; FW: 636.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

POOH

CF3

CF3

100mg

15-139315-1393

a

(11bS)-4-Hydroxy-2,6-bis[4-(trifluoromethyl)phenyl]-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 95%, (99% ee) (1264573‑23‑0) C34H19F6O4P; FW: 636.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

15-371315-3713

a

(11bS)-4-Hydroxy-2,6-bis(2,4,6-trimethylphenyl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin (878111‑18‑3) C38H33O4P; FW: 584.64; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

15-371215-3712

a

(11bR)-4-Hydroxy-2,6-bis(2,4,6-trimethylphenyl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (695162‑87‑9) C38H33O4P; FW: 584.64; white to yellow pwdr.; m.p. 224-230.5° Note: Sold in collaboration with Daicel for research purposes only.

OO

POOH

Me

MeMe

Me

Me Me

50mg

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PHOSPHORUS (Compounds)15-138115-1381

a

(11bR)-4-Hydroxy-2,6-bis[2,4,6-tris(1-methylethyl)phenyl]-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (791616‑63‑2) C50H57O4P; FW: 753.0; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

POH

Oi-Pr

i-Pr

i-Pr i-Pr

i-Pri-Pr

100mg

15-138215-1382

a

(11bS)-4-Hydroxy-2,6-bis[2,4,6-tris(1-methylethyl)phenyl]-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (874948‑63‑7) C50H57O4P; FW: 753.0; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

15-138815-1388

a

(11bR)-4-Hydroxy-2,6-di-1-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (864943‑23‑7) C40H25O4P; FW: 600.6; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

POOH

100mg

15-138915-1389

a

(11bS)-4-Hydroxy-2,6-di-1-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (929097‑93‑8) C40H25O4P; FW: 600.6; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

15-139015-1390

a

(11bR)-4-Hydroxy-2,6-di-2-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (791616‑56‑3) C40H25O4P; FW: 600.6; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

POOH

100mg

15-139115-1391

a

(11bS)-4-Hydroxy-2,6-di-2-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (874948‑60‑4) C40H25O4P; FW: 600.6; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

15-138615-1386

a

(11bR)-4-Hydroxy-2,6-diphenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (695162‑86‑8) C32H21O4P; FW: 500.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

PO

OH

100mg

15-138715-1387

a

(11bS)-4-Hydroxy-2,6-diphenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (874948‑59‑1) C32H21O4P; FW: 500.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

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PHOSPHORUS (Compounds)15-082015-0820

a

(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-bis(triphenylsilyl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (957790‑94‑2) C56H49O4PSi2; FW: 873.13; white to yellow pwdr.; m.p. >264° Note: Sold in collaboration with Daicel for research purposes only.

O

O

SiPh3

SiPh3

PO

OH

50mg

15-082115-0821

a

(11bS)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-bis(triphenylsilyl)-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1157989‑25‑7) C56H49O4PSi2; FW: 873.13; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

15-138315-1383

a

(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-di-1-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1242066‑20‑1) C40H33O4P; FW: 608.7; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

O

OH

25mg 100mg

15-138415-1384

a

(11bS)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-di-1-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) C40H33O4P; FW: 608.7; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

15-137815-1378

a

(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-di-2-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (922711‑75‑9) C40H33O4P; FW: 608.7; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

PO

OH

25mg 100mg

15-137915-1379

a

(11bS)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-di-2-naphthalenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) C40H33O4P; FW: 608.7; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

25mg 100mg

15-139615-1396

a

(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-diphenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (791616‑65‑4) C32H29O4P; FW: 508.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

Ph

Ph

PO

OH

100mg

15-139715-1397

a

(11bS)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-diphenyl-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (945852‑48‑2) C32H29O4P; FW: 508.5; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

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PHOSPHORUS (Compounds)15-137015-1370

a

(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (297752‑25‑1) C20H21O4P; FW: 356.4; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO

PO

OH

100mg

15-137115-1371

a

(11bS)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin, 98%, (99% ee) (1193697‑61‑8) C20H21O4P; FW: 356.4; White to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

15-037715-0377 (11aR)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-di-

1-naphthalenyl-5-oxide-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1297613‑73‑0) C37H27O4P; FW: 566.59; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only. O

OP

OOH

50mg

15-218515-2185

a

(11aS)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-di-1-naphthalenyl-5-oxide-diindeno[7,1-de:1’,7’-fg] [1,3,2]dioxaphosphocin 98% (99% ee) (1258327‑08‑0) C37H27O4P; FW: 566.59; white to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

15-219015-2190

a

(11aR)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-di-2-naphthalenyl-5-oxide-diindeno[7,1-de:1’,7’-fg] [1,3,2]dioxaphosphocin, 98% (99% ee) (1297613‑74‑1) C37H27O4P; FW: 566.59; white to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

O

OP

OOH

50mg

15-029015-0290

a

(11aS)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-di-2-naphthalenyl-5-oxide-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) C37H27O4P; FW: 566.59; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

15-217015-2170

a

(11aR)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-diphenyl-diindeno[7,1-de:1’,7’-fg] [1,3,2]dioxa-phosphocin, 98% (99% ee) (1297613‑72‑9) C29H23O4P; FW: 466.46; white to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO P

O

OH

50mg

15-217115-2171

a

(11aS)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-diphenyl-diindeno[7,1-de:1’,7’-fg] [1,3,2]dioxaphosphocin, 98% (99% ee) (1258327‑04‑6) C29H23O4P; FW: 446.46; white to light-yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

50mg

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PHOSPHORUS (Compounds)15-596515-5965 (11aR)-10,11,12,13-Tetrahydro-5-hydroxy-5-oxide-

diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99%) (1352810‑35‑5) C17H15O4P; FW: 314.27; white to yellow pwdr. Note: Sold in collaboration with Daicel for research purposes only.

OO P

O

OH

100mg

15-596615-5966

a

(11aS)-10,11,12,13-Tetrahydro-5-hydroxy-5-oxide-diindeno[7,1-de:1’,7’-fg][1,3,2]dioxaphosphocin, 98%, (99% ee) (1258327‑03‑5) C17H15O4P; FW: 314.27; orange pwdr. Note: Sold in collaboration with Daicel for research purposes only.

100mg

15-055715-0557

a

(11aS)-1,2,10,11-Tetramethyl-4,8-bis(t-butyl)-6-[[(2S,5S)-(2,5-diphenyl-1-phos-pholanyl) methoxy]-dibenzo[d,f][1,3,2]dioxaphosphepin] SaxS,S-BOBPHOS (1373349‑83‑7) C41H50O3P2; FW: 652.78; white microxtl. pwdr. moisture sensitive

100mg500mg

Technical Notes:1. Rhodium/phospholane catalysts for the unusually high regioselectivity in the enantioselective

hydroformylation of vinyl arenes.2. An asymmetric hydroformylation catalyst that delivers branched aldehydes from alkyl alkenes

Ar

ligandRh(acac)(CO)2

Ar

OHC

H2/CO (~3 bar)

S/C up to 10000up to 92% eeB:L > 50/1

Tech. Note (1)Ref. (1)

R

RCHO

0.4% [Rh(acac)(CO)2

0.5 mol% (SaxS,S)-BobPhos

CO/H2 (5 bar)toluene, 15°C

75-90% branchedaldehyde selectivity:up to 93% ee

Tech. Note (2)Ref. (2)

References:1. Chem Commun., 2014, 50, 1475.2. Angew. Chem. Int. Ed., 2012, 51, 2477.

15-109915-1099

a

1,3,5,7-Tetramethyl-8-(2-di-o-tolylphosphinophenyl)-2,4,6-trioxa-8-phosphaadamantane PAd-DalPhos (1902911‑38‑9) C30H34O3P2; FW: 504.54; white pwdr. air sensitive, moisture sensitive

P(o-tolyl)2

P

OOO

250mg 1g

O

OP

Me

MeMe

Me

tBu

tBu

P

Ph

Ph

O

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PHOSPHORUS (Compounds)15-093515-0935

a

Tris(1-adamantyl)phosphine, 97% (897665‑73‑5) C30CH45P; FW: 436.65; white to off-white pwdr. air sensitive Note: Sold in collaboration with GreenCentre for research purposes only. Patents: 62248056.

250mg 1g 5g

Technical Note:1. A stable phosphine ligand which can bind to metals such as palladium

to be used in Suzuki-Miyaura couplings in making drug intermediates. Dramatic effects in catalysis are also accessible now by using PAd3 as a ligand during Suzuki-Miyaura cross-coupling of chloro(hetero)arenes.1,2

Ad3P

Pd

NH

C

O

Me

Ar-Y + (HO)2B-R

(Y = Cl, Br)K3PO4 or K2CO3

THF, tol, or BuOH

(x mol%)Ar-R

OTs

Tech. Note (1)Ref. (1,2)

References:1. Synlett., 2017, 28(3), 280-288.2. J. Am. Chem. Soc., 2016, 138, 6392.

15-772515-7725

a

Tris(2,6-dimethoxyphenyl)phosphine, min. 97% (85417‑41‑0) C24H27O6P; white to off-white pwdr.; m.p. 145-147° air sensitive

5g

PLATINUM (Elemental Forms) 78-301578-3015

a

Platinum nanoparticles, 1% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

78-302078-3020

a

Platinum nanoparticles, 5% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

78-303078-3030

a

Platinum nanoparticles, 10% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g 5g

78-303278-3032

a

Platinum nanoparticles, 20% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

78-303578-3035

a

Platinum nanoparticles, 30% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

P

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PLATINUM (Elemental Forms)15-093515-0935

a

Tris(1-adamantyl)phosphine, 97% (897665‑73‑5) C30CH45P; FW: 436.65; white to off-white pwdr. air sensitive Note: Sold in collaboration with GreenCentre for research purposes only. Patents: 62248056.

250mg 1g 5g

Technical Note:1. A stable phosphine ligand which can bind to metals such as palladium

to be used in Suzuki-Miyaura couplings in making drug intermediates. Dramatic effects in catalysis are also accessible now by using PAd3 as a ligand during Suzuki-Miyaura cross-coupling of chloro(hetero)arenes.1,2

Ad3P

Pd

NH

C

O

Me

Ar-Y + (HO)2B-R

(Y = Cl, Br)K3PO4 or K2CO3

THF, tol, or BuOH

(x mol%)Ar-R

OTs

Tech. Note (1)Ref. (1,2)

References:1. Synlett., 2017, 28(3), 280-288.2. J. Am. Chem. Soc., 2016, 138, 6392.

15-772515-7725

a

Tris(2,6-dimethoxyphenyl)phosphine, min. 97% (85417‑41‑0) C24H27O6P; white to off-white pwdr.; m.p. 145-147° air sensitive

5g

PLATINUM (Elemental Forms) 78-301578-3015

a

Platinum nanoparticles, 1% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

78-302078-3020

a

Platinum nanoparticles, 5% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g 25g

78-303078-3030

a

Platinum nanoparticles, 10% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g 5g

78-303278-3032

a

Platinum nanoparticles, 20% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

78-303578-3035

a

Platinum nanoparticles, 30% on carbon black (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; black solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

P

78-301278-3012

a

Platinum nanoparticles, 1% on Titania (anatase) (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; gray solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g25g

78-300578-3005

a

Platinum nanoparticles, 1% on Titania (rutile) (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; light gray solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

5g25g

78-302678-3026

a

Platinum nanoparticles, 10% on Titania (anatase) (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; dark gray solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

78-302378-3023

a

Platinum nanoparticles, 10% on Titania (rutile) (surfactant and reactant-free) (7440‑06‑4) Pt; FW: 195.10; dark gray solid (store cold) Note: Manufactured by laser ablation. Sold in collaboration with Particular® for research purposes only.

1g5g

PLATINUM (Compounds) 78-045578-0455

a

cis-Dichlorodiammineplatinum (II), CISPLATIN (USP) (15663‑27‑1) cis-Pt(NH3)2Cl2; FW: 300.06; yellow to orange xtl.; m.p. 230°

1g 5g

98-135098-1350

a

(Trimethyl)methylcyclopentadienylplatinum(IV), 99% (99.999%-Pt) PURATREM (94442‑22‑5) (CH3)3(CH3C5H4)Pt; FW: 319.32; off-white pwdr.; m.p. 30-31°; b.p. (subl. 23°C/0.053mm); d. 1.88 air sensitive, (store cold)

PtMe Me

Me

Me 500mg 2g 10g

PRASEODYMIUM (Compounds) 59-100059-1000

a

Tris[N,N,N,N-tetramethylguanidinium][-tris(1S)-(1,1’-binaphalene)-2,2’-diolato]praseodymate Pr-HTMG-B C75H78N9O6Pr; FW: 1342.38; off-white pwdr. Note: U.S.Patent 14/898,925.

250mg1g

Technical Note:1. See 57-1250 (page 43)

OO

Pr

OO

OO

NMe2

N NMe2+HH

Me2N

NMe2N + HH

NMe2

N

Me2N

HH+

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RUTHENIUM (Compounds)RUTHENIUM (Compounds)

44-608544-6085

a

Allylbis(2-aminoethyldiphenylphosphino)ruthenium(II) tetrafluoroborate, 98% (1352633‑94‑3) C31H37BF4N2P2Ru; FW: 687.46; off-white to pale yellow solid Note: Sold in collaboration with GreenCentre for research purposes only. Patents: PCT/2013/010275.

BF4-

NH2

Ph2P

H2NPPh2

Ru+

100mg 500mg

Technical Notes:1. A highly active catalyst for the hydrogenation of amides to alcohols and amines.2. Catalyst used for the hydrogenation of functionalized amides under basic and neutral conditions.

N

O

Rn R

x

+ 2H2 Ru complex

4-5 mol% baseTHF, 24 h, TON up to 7120

HN

OH

Rn R

x

Tech. Note (1)Ref. (1)

O

N

R

R'

O

+ 2H2

O

N

H

R'

OH

R

+

Ru complexbase-free or base-assisted

THF, 50 atm H2, 100°C, 24 h

TONs up to 500

Tech. Note (2)Ref. (2)

References:1. Angew. Chem. Int. Ed., 2011, 50, 10377.2. Catal. Sci. Technol., 2015, 5, 1186.

44-075944-0759

a

(1,3-Bis(2,6-diisopropylphenyl)-4-((4-ethyl-4-methylpiperzain-1-ium-1-yl)methyl)imidaz-olidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(II) chloride dihydrate FixCat (1799947‑97‑9) C45H67Cl2N4ORuCl 2(H2O); FW: 887.47 (923.50); green pwdr. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790; PCT/EP2013/053967

100mg 500mg

Technical Note:1. Fixcat is a stable olefin metathesis initiator with very good

solubility in neat water. The product efficiently promotes ring-closing, cross, and enyne metathesis reactions of water soluble substrates. Suitable for homogeneous and heterogeneous in batch or flow setup.

The Fixcat structure was also optimized to serve as a versatile and very stable catalyst, easily immobilized on solid supports. In its SCA-15 supported version, it showed exceptional efficiency in promoting ring- closing and cross-metathesis reactions, in both batch and continuous flow setups. Fix Cat is also applicable as a homogeneous catalyst, where compatible solvents include alcohols and halogenated solvents.

NTs FixCat (20ppm)

Toluene, 1.0M 45°C, 71%

Ts

TON 35500TOF10 min 1590 min-1

Tech. Note (1)Ref. (1)

References:1. ChemSus Chem., 2015, 8, 4139.

N N

Ru

iPr

iPriPr

iPr

Cl

ClO

iPr

N

NEt Me+

Cl-

2H2O

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RUTHENIUM (Compounds)RUTHENIUM (Compounds)

44-608544-6085

a

Allylbis(2-aminoethyldiphenylphosphino)ruthenium(II) tetrafluoroborate, 98% (1352633‑94‑3) C31H37BF4N2P2Ru; FW: 687.46; off-white to pale yellow solid Note: Sold in collaboration with GreenCentre for research purposes only. Patents: PCT/2013/010275.

BF4-

NH2

Ph2P

H2NPPh2

Ru+

100mg 500mg

Technical Notes:1. A highly active catalyst for the hydrogenation of amides to alcohols and amines.2. Catalyst used for the hydrogenation of functionalized amides under basic and neutral conditions.

N

O

Rn R

x

+ 2H2 Ru complex

4-5 mol% baseTHF, 24 h, TON up to 7120

HN

OH

Rn R

x

Tech. Note (1)Ref. (1)

O

N

R

R'

O

+ 2H2

O

N

H

R'

OH

R

+

Ru complexbase-free or base-assisted

THF, 50 atm H2, 100°C, 24 h

TONs up to 500

Tech. Note (2)Ref. (2)

References:1. Angew. Chem. Int. Ed., 2011, 50, 10377.2. Catal. Sci. Technol., 2015, 5, 1186.

44-075944-0759

a

(1,3-Bis(2,6-diisopropylphenyl)-4-((4-ethyl-4-methylpiperzain-1-ium-1-yl)methyl)imidaz-olidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(II) chloride dihydrate FixCat (1799947‑97‑9) C45H67Cl2N4ORuCl 2(H2O); FW: 887.47 (923.50); green pwdr. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790; PCT/EP2013/053967

100mg 500mg

Technical Note:1. Fixcat is a stable olefin metathesis initiator with very good

solubility in neat water. The product efficiently promotes ring-closing, cross, and enyne metathesis reactions of water soluble substrates. Suitable for homogeneous and heterogeneous in batch or flow setup.

The Fixcat structure was also optimized to serve as a versatile and very stable catalyst, easily immobilized on solid supports. In its SCA-15 supported version, it showed exceptional efficiency in promoting ring- closing and cross-metathesis reactions, in both batch and continuous flow setups. Fix Cat is also applicable as a homogeneous catalyst, where compatible solvents include alcohols and halogenated solvents.

NTs FixCat (20ppm)

Toluene, 1.0M 45°C, 71%

Ts

TON 35500TOF10 min 1590 min-1

Tech. Note (1)Ref. (1)

References:1. ChemSus Chem., 2015, 8, 4139.

N N

Ru

iPr

iPriPr

iPr

Cl

ClO

iPr

N

NEt Me+

Cl-

2H2O

44-074844-0748

a

[1,3-Bis(2,6-di-i-propylphenyl)imidazolidin-2-ylidene][(2-((1-methoxy(methyl)amino)-1-oxopropan-2-yl)oxy]benzylidenediiodoruthenium(II) GreenCat-I2 C39H53I2N3O3Ru; FW: 966.74; green solid air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/666,009PCT/EP2013/062435. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air

Ru

O

MeN

Me

O

Me

IO

I

NN

iPr

iPr

iPr

iPr

100mg500mg

44-077044-0770

a

1,3-Bis(2,6-di-i-propylphenyl)imidazoli-din-2-ylidene)(2-i-propoxy-5-nitrobenzylidene) ruthenium(II) dichloride Nitro-Grela SiPr (928795‑51‑1) C37H49Cl2N3O3Ru; FW: 755.78; green pwdr. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air

Ru

O

iPr

Cl

Cl

NN

iPr

iPr

iPr

iPr

NO2

100mg500mg

44-078244-0782

a

[1,3-Bis(2,6-di-i-propylphenyl)imidazoli-din-2-ylidene)(2-i-propoxy-5-nitrobenzylidene) ruthenium(II) diiodide nitro-Grela I2 SIPr (1874265‑00‑5) C37H49I2N3O3Ru; FW: 938.68; olive brown pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8ºC under inert atmosphere. Catalyst may be weighed in air

Ru

O

NN

iPr

iPr

iPr

iPr

I

iPrNO2

I

100mg500mg

44-079344-0793

a

[1,3-Bis(2,6-di-i-propylphenyl)imidaz-olidin-2-ylidene)(tricyclohexylphos-phine)-(2-oxo-5-nitrobenzylidene)ruthenium(II) chloride LatMet SIPr (1544328‑59‑7) C52H77ClN2OPRu; FW: 913.68; dark green xtl. air sensitive Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 9,328,132, PCT/EP2013/065839.

Ru

O

NN

iPr

iPr

iPr

iPr

Cy3P

Cl

100mg500mg

44-005644-0056

aamp

Bis(N,N’-di-tert-butylacetamidinato)ruthenium(II) dicarbonyl, 98% (99.99%-Ru) PURATREM (949113‑49‑9) C22H42N4O2Ru; FW: 495.67; Beige to yellow solid; m.p. 204 air sensitive, moisture sensitive Note: Product sold under, use subject to, terms and conditions of label license at www.strem.com/harvard2

NRu

N N

N

tBu

tBu

tBu

tBu

Me Me

CO

CO

1g5g

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RUTHENIUM (Compounds)44-035544-0355

a

[Bis(pyrazol-1-yl)(acetimino)hydridoborato](p-cymene)ruthenium(II) trifluoromethanesul-fonate (1607436‑49‑6) C19H25BF3N5O3RuS; FW: 572.38; yellow pwdr. Note: Sold under license from USC for research purposes only. U.S. Patent No. 62/082,992.

MeN

N

N

NRu

BH

N Me

CF3SO3-

iPr

+

100mg500mg

Technical Note:1. Dual site catalyst for the mild, selective nitrile reduction.

CNO2N

Ru catalyst NaBH4

92%

NH2

O2N Tech. Note (1)Ref. (1)

References:1. Chem. Comm., 2014, 50(40), 5391.

44-075544-0755

a

1,3-Bis(2,4,6-trimethylphenyl)-4-[(trimethylammonio)methyl]imidazolidin-2-ylidene]-(2-i-propoxybenzylidene)dichlororuthenium(II) hexafluorophosphate StickyCat PF6 C35H48Cl2F6N3OPRu; FW: 843.72; green pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790, PCT/EP2013/053967. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

NNMe

Me

Me

Me

MeMe

Cl

iPr

Me3N+PF6

-

Cl

100mg 500mg

44-079544-0795

a

1,3-Bis(2,4,6-trimethylphenyl)-4-[(trimethylammonio)methyl]imidazolidin-2-ylidene]-(2-i-propoxy-5-nitrobenzylidene)dichlororuthenium(II) chloride nitro-StickyCat Cl (1415661‑45‑8) C35H47Cl3N4O3Ru; FW: 779.20; green pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790 PCT/EP2013/053967. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

iPr

Cl

Cl

NN

Me

Me

Me

Me

MeMe

Me3N + Cl-

NO2

100mg 500mg

44-076744-0767

a

[1,3-Bis(2,4,6-trimethylphenyl)imidazo-lidin-2-ylidene)-(2-i-propoxy-5-nitroben-zylidene) ruthenium(II) diiodide nitro-Grela I2 (1874264‑99‑9) C31H37I2N3O3Ru; FW: 854.52; olive brown pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

NN

Me

Me

Me

Me

MeMe

I

iPrNO2

I

100mg 500mg

44-078744-0787

a

[1,3-Bis(2,4,6-trimethylphenylimidazolidin-2-ylidene)(tricyclohexylphosphine)-(2-oxo-5-nitrobenzylidene)ruthenium(II) chloride Nitro-LatMet (1544328‑53‑1) C46H64ClN3O3PRu; FW: 874.52; brown xtl. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 9,328,132, PCT/EP2013/065839.

Ru

O

NN

Me

Me

Me

Me

MeMe

Cy3P

Cl

NO2

100mg 500mg

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RUTHENIUM (Compounds)44-035544-0355

a

[Bis(pyrazol-1-yl)(acetimino)hydridoborato](p-cymene)ruthenium(II) trifluoromethanesul-fonate (1607436‑49‑6) C19H25BF3N5O3RuS; FW: 572.38; yellow pwdr. Note: Sold under license from USC for research purposes only. U.S. Patent No. 62/082,992.

MeN

N

N

NRu

BH

N Me

CF3SO3-

iPr

+

100mg500mg

Technical Note:1. Dual site catalyst for the mild, selective nitrile reduction.

CNO2N

Ru catalyst NaBH4

92%

NH2

O2N Tech. Note (1)Ref. (1)

References:1. Chem. Comm., 2014, 50(40), 5391.

44-075544-0755

a

1,3-Bis(2,4,6-trimethylphenyl)-4-[(trimethylammonio)methyl]imidazolidin-2-ylidene]-(2-i-propoxybenzylidene)dichlororuthenium(II) hexafluorophosphate StickyCat PF6 C35H48Cl2F6N3OPRu; FW: 843.72; green pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790, PCT/EP2013/053967. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

NNMe

Me

Me

Me

MeMe

Cl

iPr

Me3N+PF6

-

Cl

100mg 500mg

44-079544-0795

a

1,3-Bis(2,4,6-trimethylphenyl)-4-[(trimethylammonio)methyl]imidazolidin-2-ylidene]-(2-i-propoxy-5-nitrobenzylidene)dichlororuthenium(II) chloride nitro-StickyCat Cl (1415661‑45‑8) C35H47Cl3N4O3Ru; FW: 779.20; green pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790 PCT/EP2013/053967. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

iPr

Cl

Cl

NN

Me

Me

Me

Me

MeMe

Me3N + Cl-

NO2

100mg 500mg

44-076744-0767

a

[1,3-Bis(2,4,6-trimethylphenyl)imidazo-lidin-2-ylidene)-(2-i-propoxy-5-nitroben-zylidene) ruthenium(II) diiodide nitro-Grela I2 (1874264‑99‑9) C31H37I2N3O3Ru; FW: 854.52; olive brown pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

NN

Me

Me

Me

Me

MeMe

I

iPrNO2

I

100mg 500mg

44-078744-0787

a

[1,3-Bis(2,4,6-trimethylphenylimidazolidin-2-ylidene)(tricyclohexylphosphine)-(2-oxo-5-nitrobenzylidene)ruthenium(II) chloride Nitro-LatMet (1544328‑53‑1) C46H64ClN3O3PRu; FW: 874.52; brown xtl. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 9,328,132, PCT/EP2013/065839.

Ru

O

NN

Me

Me

Me

Me

MeMe

Cy3P

Cl

NO2

100mg 500mg

44-103544-1035

a

Carbonylchlorohydrido[bis(2-di-t-butylphosphinoethyl)amine]ruthenium(II), min. 97% (1421060‑10‑7) C21H46ClNOP2Ru; FW: 527.07; off-white solid air sensitive

RuP

P

CO

N

H

Cl tBu

tBu

tBu

tBu

H 250mg 1g

44-104344-1043

a

Carbonylchlorohydrido[bis(2-di-cyclohexyl-phosphinoethyl)amine]ruthenium(II), min. 97% (1421060‑11‑8) C29H54ClNOP2Ru; FW: 631.22; white solid air sensitive

RuP

P

CO

N

H

Cl Cy

CyCy

H

Cy

250mg1g

Technical Notes:1. Catalyst for the hydrogenation of ethylene carbonate to methanol.2. Catalyst for the generation of hydrogen from aqueous ethanol solution.3. Catalyst for the N-formylation of morpholine with hydrogen and carbon dioxide.

OO

O

+ H250 atm THF, 140°C

Catalyst, KOtBu OHHO + MeOH + HCOOMe Tech. Note (1)Ref. (1)

NaOH/H2OCatalyst

OH H2Tech. Note (2)Ref. (2)

CO2 + H2 +N

O

H

CatalysttBuOK, THF, 120°C

NH

O

OTech. Note (3)Ref. (3)

References:1. Angew. Chem. Int. Ed., 2012, 51, 13041.2. ChemSusChem, 2014, 7, 2419.3. Angew. Chem. Int. Ed., 2015, 54, 6186.

44-103244-1032

a

Carbonylchlorohydrido[bis(2-di-i-propylphos-phinoethyl)amine]ruthenium(II), min. 97% (1311164‑69‑8) C17H38ClNOP2Ru; FW: 470.96; off-white solid air sensitive

RuP

P

CO

N

H

Cl iPr

iPr

iPr

iPr

H 250mg 1g

Technical Notes:1. Catalyst for hydrogenation of ethylene carbonate to methanol.2. Catalyst for dehydrogenation of aqueous-phase methanol to hydrogen and carbon dioxide.3. Catalyst for hydrogenation of diethyl oxalate.4. Catalyst for generation of hydrogen from aqueous ethanol solution.5. Ruthenium- catalyzed hydrogen generation from glycerol and selective synthesis of lactic acid.6. Catalyst N-formylation of morpholine with hydrogen and carbon dioxide.

OO

O

+ H250 atm THF, 140°C

Catalyst, KOtBu OHHO + MeOH + HCOOMe Tech. Note (1)Ref. (1)

MeOH + H2O H2 + CO20.5 M NaOH, 72.0 ºC

Catalyst Tech. Note (2)Ref. (2)

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RUTHENIUM (Compounds)

EtO

O OEt

O

H2; - EtOH

EtO

O OHTech. Note (3)Ref. (3)

NaOH/H2OCatalyst

OH H2Tech. Note (4)Ref. (4)

KOH, 110°C, 24 hrCatalystHO OH

OHH2 + O

OH

OH

Tech. Note (5)Ref. (5)

CO2 + H2 +N

O

H

CatalysttBuOK, THF, 120°C

NH

O

OTech. Note (6)Ref. (6)

References:1. Angew. Chem. Int. Ed., 2012, 51, 13041.2. Nature, 2013, 495, 85.3. ChemCatChem, 2013, 5, 3228.4. ChemSusChem, 2014, 7, 2419.5. Green Chem., 2015, 17, 193.6. Angew. Chem. Int. Ed., 2015, 54, 6186.

44-079744-0797

a

Dichloro(1,3-Bis(2,6-di-i-propylphenyl)-4-((4-ethyl-4-methylpiperzain-1-ium-1-yl)methyl)im-idazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(II) hexafluorophosphate FixCat PF6 C45H67Cl2F6N4OPRu; FW: 996.98; green pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790 PCT/EP2013/053967. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

N N

Ru

iPr

iPriPr

iPr

ClO

iPr

N

NEt Me+

PF6-

Cl

100mg500mg

44-076044-0760

a

Dichloro(1,3-bis(2,4,6-trimethylphenyl)imidaz-olidin-2-ylidene){2-[(ethoxy-2-oxoethylidene)amino]benzylidene}ruthenium(II) HeatMet C32H37Cl2N3O2Ru; FW: 667.63; dark purple xtls. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 14/443,034; PCT/IN2013/002543.

N N

Ru

Me

MeMe

Me

Cl

ClN

Me Me

OEt

O

100mg500mg

Technical Note:1. HeatMet catalyst is a highly efficient latent catalyst, requiring thermal activation to in initiate catalytic

activity. Its characteristics are especially suitable to mold polymerization of reactive monomers such as dicyclopentadiene (DCPD). The product is soluble in toluene and dichloromethane.

HeatMet Tech. Note (1)Ref. (1)

References:1. ChemSus Chem., 2015, 8, 4139.

44-1032(cont.)

Carbonylchlorohydrido[bis(2-di-i-propylphosphinoethyl)amine]ruthenium(II), min. 97% (1311164‑69‑8)

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RUTHENIUM (Compounds)

EtO

O OEt

O

H2; - EtOH

EtO

O OHTech. Note (3)Ref. (3)

NaOH/H2OCatalyst

OH H2Tech. Note (4)Ref. (4)

KOH, 110°C, 24 hrCatalystHO OH

OHH2 + O

OH

OH

Tech. Note (5)Ref. (5)

CO2 + H2 +N

O

H

CatalysttBuOK, THF, 120°C

NH

O

OTech. Note (6)Ref. (6)

References:1. Angew. Chem. Int. Ed., 2012, 51, 13041.2. Nature, 2013, 495, 85.3. ChemCatChem, 2013, 5, 3228.4. ChemSusChem, 2014, 7, 2419.5. Green Chem., 2015, 17, 193.6. Angew. Chem. Int. Ed., 2015, 54, 6186.

44-079744-0797

a

Dichloro(1,3-Bis(2,6-di-i-propylphenyl)-4-((4-ethyl-4-methylpiperzain-1-ium-1-yl)methyl)im-idazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(II) hexafluorophosphate FixCat PF6 C45H67Cl2F6N4OPRu; FW: 996.98; green pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 61/603,790 PCT/EP2013/053967. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

N N

Ru

iPr

iPriPr

iPr

ClO

iPr

N

NEt Me+

PF6-

Cl

100mg500mg

44-076044-0760

a

Dichloro(1,3-bis(2,4,6-trimethylphenyl)imidaz-olidin-2-ylidene){2-[(ethoxy-2-oxoethylidene)amino]benzylidene}ruthenium(II) HeatMet C32H37Cl2N3O2Ru; FW: 667.63; dark purple xtls. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 14/443,034; PCT/IN2013/002543.

N N

Ru

Me

MeMe

Me

Cl

ClN

Me Me

OEt

O

100mg500mg

Technical Note:1. HeatMet catalyst is a highly efficient latent catalyst, requiring thermal activation to in initiate catalytic

activity. Its characteristics are especially suitable to mold polymerization of reactive monomers such as dicyclopentadiene (DCPD). The product is soluble in toluene and dichloromethane.

HeatMet Tech. Note (1)Ref. (1)

References:1. ChemSus Chem., 2015, 8, 4139.

44-079244-0792

a

Dichloro(1,3-di-i-propylimidazoli-din-2-ylidene){2-[(ethoxy-2-oxoethylidene)amino]benzylidene} ruthenium(II) HeatMet SIPr (2097273‑88‑4) C38H49Cl2N3O2Ru; FW: 751.79; dark violet pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 14/443,034.

N N

Ru

iPr

iPriPr

iPr

ClNO

Et

O

Cl

100mg 500mg

44-042844-0428

a

Dichloro(mesitylene)ruthenium(II) dimer, 98% (52462‑31‑4) C18H24Cl4Ru2; FW: 584.33; red pwdr. air sensitive, (store cold)

500mg2g

Technical Notes:1. Catalyst for asymmetric transfer hydrogenation of

cyclic imines and iminiums in water.2. Catalyst for selective hydration of nitriles to amides in

pure aqueous medium under neutral conditions.3. Catalyst for reduction of allylic alcohol using alcohols

as solvent and hydrogen donor.4. Catalyst for selective hydrosilylation of primary amides into secondary amines with PhSiH3.

Tech. Note (1)Ref. (1)

R C NR NH2

O

R = Alkyl, aryl, heteroaryl, alkenyl

[RuCl2(mesitylene)]2/P-N LigandsH2O/100°C/1-15h Tech. Note (2)

Ref. (2,5)

Ru CatalystR4

OH

R1

R2

R3

R4

OH

R1

R2

R3

R OH

Tech. Note (3)Ref. (3,4)

[RuCl2(mesitylene)]2NH2R

O

HNR RSilane, 100°C

Tech. Note (4)Ref. (6)

References:1. Chem. Commun., 2006, 1766.2. Chem. Eur. J. 2008, 14, 6601.3. Green Chem., 2009, 11, 1992.4. Catal. Commun. 2011, 13, 91.5. Organometallics 2011, 30, 5442.

RuCl

RuCl

Cl Cl

Me

Me

Me

Me

Me

Me

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RUTHENIUM (Compounds)44-046044-0460

a

Dihydrotetrakis(triphenylphosphine)ruthenium(II), 95% (19529‑00‑1) C72H62P4Ru; FW: 1152.23; yellow to green pwdr.; m.p. 181-183° air sensitive

PPh

PhPh

4

RuH

H

250mg 1g

Technical Notes:1. Catalyst for transfer hydrogenation of ketones with alcohols involving carbon-carbon bond formation.2. Catalyst for oxidative cyclization of 2-aminobenzyl alcohol with ketones.3. Amidation catalyst of alcohols or aldehydes with amines.4. Stereoselective semireduction of internal alkynes to Z-olefins under transfer hydrogenation conditions.5. Catalyst for synthesis of cyclic imides from nitriles and diols via hydrogen transfer mechanism.6. Catalyst for direct hydrogenation of carboxylic acids using triphos-type ligands.

R

OR' OH+

R

OH

R'

Ru Catalyst Tech. Note (1)Ref. (1)

R

O+

Ru Catalyst

NH2

OH

N R

Tech. Note (2)Ref. (2)

Ru Catalyst

R1 H

OH2N R2+

R1 NH

R2

O

R1 OHor Tech. Note (3)Ref. (3)

Ru CatalystR1 R2

R1 R2Tech. Note (4)Ref. (4)

Ru CatalystR1 CN

HOR2

R3HON

R2

R3

O

O

R1 + 2H2+ Tech. Note (5)Ref. (5)

Ru Catalyst/N-(PR)3

R OH

O

R OH70 bar H2

Tech. Note (6)Ref. (6)

References:1. J. Org. Chem., 2001, 66, 9020.2. Chem. Commun., 2001, 2576.3. J. Org. Chem., 2010, 75, 3002.4. Chem. Eur. J., 2010, 16, 12214.5. Org. Lett., 2014, 16, 4404.6. ChemSusChem., 2016, 9, 177.

44-074044-0740

a

(1,3-Di-o-tolylimidazolidin-2-ylidene)(2-i-prop-oxy-5-nitrobenzylidene)dichlororuthenium(II) Nitro-Grela SI-o-Tolyl C27H29Cl2N3O3Ru; FW: 615.51; green pwdr. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

NN

Me

Me

Cl

iPrNO2

Cl

100mg 500mg

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RUTHENIUM (Compounds)44-046044-0460

a

Dihydrotetrakis(triphenylphosphine)ruthenium(II), 95% (19529‑00‑1) C72H62P4Ru; FW: 1152.23; yellow to green pwdr.; m.p. 181-183° air sensitive

PPh

PhPh

4

RuH

H

250mg 1g

Technical Notes:1. Catalyst for transfer hydrogenation of ketones with alcohols involving carbon-carbon bond formation.2. Catalyst for oxidative cyclization of 2-aminobenzyl alcohol with ketones.3. Amidation catalyst of alcohols or aldehydes with amines.4. Stereoselective semireduction of internal alkynes to Z-olefins under transfer hydrogenation conditions.5. Catalyst for synthesis of cyclic imides from nitriles and diols via hydrogen transfer mechanism.6. Catalyst for direct hydrogenation of carboxylic acids using triphos-type ligands.

R

OR' OH+

R

OH

R'

Ru Catalyst Tech. Note (1)Ref. (1)

R

O+

Ru Catalyst

NH2

OH

N R

Tech. Note (2)Ref. (2)

Ru Catalyst

R1 H

OH2N R2+

R1 NH

R2

O

R1 OHor Tech. Note (3)Ref. (3)

Ru CatalystR1 R2

R1 R2Tech. Note (4)Ref. (4)

Ru CatalystR1 CN

HOR2

R3HON

R2

R3

O

O

R1 + 2H2+ Tech. Note (5)Ref. (5)

Ru Catalyst/N-(PR)3

R OH

O

R OH70 bar H2

Tech. Note (6)Ref. (6)

References:1. J. Org. Chem., 2001, 66, 9020.2. Chem. Commun., 2001, 2576.3. J. Org. Chem., 2010, 75, 3002.4. Chem. Eur. J., 2010, 16, 12214.5. Org. Lett., 2014, 16, 4404.6. ChemSusChem., 2016, 9, 177.

44-074044-0740

a

(1,3-Di-o-tolylimidazolidin-2-ylidene)(2-i-prop-oxy-5-nitrobenzylidene)dichlororuthenium(II) Nitro-Grela SI-o-Tolyl C27H29Cl2N3O3Ru; FW: 615.51; green pwdr. (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

NN

Me

Me

Cl

iPrNO2

Cl

100mg 500mg

44-076344-0763

a

Tricyclohexylphosphine(2-i-propoxy-5-nitroben-zylidene)dichlororuthenium(II) Nitro-Grela 1 gen. (625082‑83‑9) C28H44Cl2NO3PRu; FW: 645.60; brown pwdr. air sensitive, (store cold) Note: Sold in collaboration with Apeiron Synthesis, Inc. U.S. Patent 6/867,303 PCT/EP2003/01122. Store at 2-8°C under inert atmosphere. Catalyst may be weighed in air.

Ru

O

PCy3

Cl

iPrNO2

Cl

100mg500mg

44-791044-7910

a

Tris(2,2’-bipyrazine)ruthenium(II) hexafluoro-phosphate, 95% (80907‑56‑8) C24H18F12N12P2Ru; FW: 865.48; red pwdr. air sensitive Note: Photocatalyst.

50mg250mg

Technical Notes:1. Endoperoxide synthesis by photocatalytic aerobic [2+2+2]

cycloadditions.2. Aerobic oxidation of a tertiary aliphatic amine under visible-light

photocatalysis. Facile synthesis of methylene-bridged bis-1,3-dicarbonyl compounds.

3. Hydrophosphinylation of unactivated alkenes with secondary phosphine oxides under visible-light photocatalysis.

4. [3+2] Photooxygenation of aryl cyclopropanes via visible light photocatalysis.5. Photocatalytic synthesis of dihydrobenzofurans by oxidative cycloaddition of phenols.

visible light

Ru catalyst O2

OMe

O

PhO

O

OH

HPh

MeO

Tech. Note (1)Ref. (1)

O O

R1 R2N

Ph+

O O

R1 R2

O O

R1 R2

1 mol% Ru catalyst

MeCN, 4Å MS, 30°C12 h, white LED, air (1 atm)

Tech. Note (2)Ref. (2)

OPR1

R1 H R2 R3+ cat.

i-PrOH, 30 or 50°C,visible light

OPR1

R1 R3

R2

27-90% yield

Tech. Note (3)Ref. (3)

MeO

Ph

O O

Ph

MeO visible light0.5 mol% Ru catalyst

O2, 1 hTech. Note (4)Ref. (4)

MeO

OH

OMe

OMe

O

OMe

OMe

Me

Ru catalyst

(NH4)2S2O8 2 (NH4)HSO4

+Tech. Note (5)Ref. (5)

2PF6-

NN

N

N

N

N

NN

NN

NN

Ru

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RUTHENIUM (Compounds)

References:1. Org. Lett., 2012, 14, 1640.2. Chemistry – An Asian Journal, 2012, 7, 2764.3. Green Chemistry, 2013, 15, 1844.4. Advanced Synthesis & Catalysis, 2014, 356, 2831.5. J. Am. Chem. Soc., 2015, 137, 5654.

44-794044-7940

a

Tris[4,4’-bis(t-butyl)-2,2’-bipyridine]ruthenium(II) hexafluorophosphate, 95% (75777‑87‑6) C54H72F12N6RuP2; FW: 1196.19; red pwdr. air sensitive Note: Photocatalyst.

50mg 250mg

Technical Notes:1. Photoredox catalysed C-P bond formation reactions

– visible light mediated oxidative phosphonylations of amines.

2. Aerobic oxidation of a tertiary aliphatic amine under visible-light photocatalysis: facile synthesis of methylene-bridged bis-dicarbonyl compounds.

3. Photoredox catalysis as an efficient tool for the aerobic oxidation of amines and alcohols.

4. Visible-light induced, direct synthesis of polysubstituted furans from cyclopropyl ketones.

N

R1

R1

R2

+

OP

R3O H

R3O

Ru catalyst 5W lamp

toluene/water

N

R1

R1

O P OR3

R2

OR3

Tech. Note (1)Ref. (1)

O O

R1 R2N

Ph+

O O

R1 R2

O O

R1 R2

1 mol% Ru catalyst

MeCN, 4Å MS, 30°C12 h, white LED, air (1 atm)

Tech. Note (2)Ref. (2)

MeN

Ar R

Ar1 NH2

R1 R2

OH

HN

Ar R

Ar1 N Ar1

R1 R2

O

Ru catalyst

O2

Tech. Note (3)Ref. (3)

ArR3

R2

O

R1

O

R2 R3

Ar R1 O

Br R3

Ar R1

Ruthenium cat. visible light

oxidativeannulation

site selective bromination

R2 = H

Tech. Note (4)Ref. (4)

References:1. Chem. Commun., 2011, 47, 8679.2. Chemistry – An Asian Journal, 2012, 7, 2764.3. ACS Catalysis, 2012, 2, 2810.4. J. Org. Chem., 2016, 81, 7008.

N

N

N

NN

N

Ru 2PF6-

tBu

tBu

tBu

tBu tBu

tBu

44-7910(cont.)

Tris(2,2’-bipyrazine)ruthenium(II) hexafluorophosphate, 95% (80907‑56‑8)

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RUTHENIUM (Compounds)

References:1. Org. Lett., 2012, 14, 1640.2. Chemistry – An Asian Journal, 2012, 7, 2764.3. Green Chemistry, 2013, 15, 1844.4. Advanced Synthesis & Catalysis, 2014, 356, 2831.5. J. Am. Chem. Soc., 2015, 137, 5654.

44-794044-7940

a

Tris[4,4’-bis(t-butyl)-2,2’-bipyridine]ruthenium(II) hexafluorophosphate, 95% (75777‑87‑6) C54H72F12N6RuP2; FW: 1196.19; red pwdr. air sensitive Note: Photocatalyst.

50mg 250mg

Technical Notes:1. Photoredox catalysed C-P bond formation reactions

– visible light mediated oxidative phosphonylations of amines.

2. Aerobic oxidation of a tertiary aliphatic amine under visible-light photocatalysis: facile synthesis of methylene-bridged bis-dicarbonyl compounds.

3. Photoredox catalysis as an efficient tool for the aerobic oxidation of amines and alcohols.

4. Visible-light induced, direct synthesis of polysubstituted furans from cyclopropyl ketones.

N

R1

R1

R2

+

OP

R3O H

R3O

Ru catalyst 5W lamp

toluene/water

N

R1

R1

O P OR3

R2

OR3

Tech. Note (1)Ref. (1)

O O

R1 R2N

Ph+

O O

R1 R2

O O

R1 R2

1 mol% Ru catalyst

MeCN, 4Å MS, 30°C12 h, white LED, air (1 atm)

Tech. Note (2)Ref. (2)

MeN

Ar R

Ar1 NH2

R1 R2

OH

HN

Ar R

Ar1 N Ar1

R1 R2

O

Ru catalyst

O2

Tech. Note (3)Ref. (3)

ArR3

R2

O

R1

O

R2 R3

Ar R1 O

Br R3

Ar R1

Ruthenium cat. visible light

oxidativeannulation

site selective bromination

R2 = H

Tech. Note (4)Ref. (4)

References:1. Chem. Commun., 2011, 47, 8679.2. Chemistry – An Asian Journal, 2012, 7, 2764.3. ACS Catalysis, 2012, 2, 2810.4. J. Org. Chem., 2016, 81, 7008.

N

N

N

NN

N

Ru 2PF6-

tBu

tBu

tBu

tBu tBu

tBu

44-793044-7930

a

Tris(4,4’-dimethyl-2,2’-bipyridine)ruthenium(II) hexafluorophosphate, 95%, DMBPY (83605‑44‑1) C36H36F12N6RuP2; FW: 943.71; red pwdr. air sensitive Note: Photocatalyst. N

N

N

NN

N

Ru 2PF6-

Me

Me

Me

Me Me

Me

50mg 250mg

44-795544-7955

a

Tris(1,10-phenanthroline)ruthenium(II) hexafluorophosphate, 95% (60804‑75‑3) C36H24F12N6RuP2; FW: 931.62; red pwdr. air sensitive Note: Photocatalyst

50mg 250mg

Technical Notes:1. Photoredox catalyst for nickel assisted cross-coupling

reactions of ammonium alkylsilicates with aryl bromides

2. A photosensitizer for cobalt catalyzed visible-light driven CO2 - Reduction to CO in CH3CN/H2O Solution

Tech. Note (1)Ref. (1)

Tech. Note (2)Ref. (2)

References:1. J. Am. Chem. Soc., 2016, 138, 475.2. Angew. Chem. Int. Ed., 2017, 56, 738.

NN

NN

N

N

Ru 2PF6-

SiR2

R Br

R3+ R3

R1

R2[Ru hv] Cat / [Ni] CatO

O 2

HNR'R"2

CO2

Ru/Co cat., hv

CH3CN/H2OCO

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SAMARIUM (Elemental Forms)SAMARIUM (Elemental Forms)

62-623562-6235

aHAZ

Samarium powder (99.9% REO) 325 mesh (7440‑19‑9) Sm; FW: 140.4; 325 mesh; m.p. 1072º; b.p. 1778º; d. 7.40 air sensitive, moisture sensitive

5g 25g

SCANDIUM (Compounds) 21-120021-1200

a

Tris(N,N’-di-i-propylformamidinato)scandium(III), (99.9%-Sc) C21H45ScN6; FW: 426.58; white to off-white pwdr. air sensitive, moisture sensitive Note: Product sold under, use subject to, terms and conditions of label license at www.strem.com/harvard2

Sc

N

N

N

NN

NiPr

iPr

iPr

iPr

iPr

iPr

1g 5g

SILICON (Compounds) 14-107214-1072

a

Bis(t-butylamino)silane, BTBAS (99.999%-Si) PURATREM (186598‑40‑3) C8H22N2Si; FW: 174.36; colorless liq.; b.p. 167°C; f.p. 30°C; d. 0.816 moisture sensitive

1g 5g 25g

14-153014-1530

a

Bis(dimethylamino)dimethylsilane, 99+% BDMADMS (3768‑58‑9) [N(CH3)2]2(CH3)2Si; FW: 146.31; colorless liq.; b.p. 128-129°; f.p. -3°C; d. 0.81 moisture sensitive

SiNN

Me Me

MeMe

Me Me

5g 25g

Technical Notes:1. Used in the chemical vapor deposition of silicon nitride films, and also the atomic layer deposition of SiNxCy

dielectric sealing layers using plasma-enhanced atomic layer deposition (PE-ALD).1,2,3,4

2. Used as a reagent for silylation.5,6

References:1. AIP Conference Proceedings, 2015, 1649(1, Irago Conference 2014), 41-46.2. Materials Science in Semiconductor Processing, 2015, 29, 139-142.3. Applied Surface Science, 2010, 257(4), 1196-1203.4. Surface and Coatings Technology, 2008, 202(9), 1606-1614.5. Microelectronic Engineering, 1991, 13(1‑4), 47-50.6. Journal of Vacuum Science & Technology, B: Microelectronics and Nanometer Structures, 1990, 8(6), 1481-7.

14-610014-6100

a

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~700 m2/g, (KCC-1 L1) (112945‑52‑5) SiO2; FW: 60.09; white pwdr.; SA: ~700 m2/g; P.Vol. ~1.4 cm3/g Note: Diameter: ~900-1000nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. Novel fibrous shaped silica nanospheres, denoted as KCC-1 (KAUST Catalysis Center)[1], have unique

physical properties which have never before been reported in silica materials. These nanomaterials have been developed by Prof. J. M. Basset of King Abdullah University of Science and Technology (KAUST). A fibrous surface morphology arranged in three-dimensional structure forms the spheres (Fig. 1). Unlike traditional pore-based silica, these nanospheres possess a fibrous structure that increases accessibility to the available surface area; this in turn, significantly increases the catalytic activity.

These materials exhibit excellent physical properties, including a high surface area, a fibrous surface morphology, good thermal and hydrothermal stabilities and high mechanical stability (Table 1). The fibrous morphology of KCC-1 remains unaffected even after mechanical compression up to 216 MPa pressure. This is superior to the conventional MCM-41 type of silica, which is affected at pressure 86 MPa.[1]

NH

tBu

SiHN

tBu

H H

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SILICON (Compounds)

A range of heterogeneous catalysts, prepared using KCC-1 as a supporting material, have been showing excellent catalytic activity for various transformations of research and industrial importance. As a catalyst support, sorbent or carrier, KCC-1 is able to demonstrate superior activity as compared to regular mesoporous silica materials in energy related processes[2-3], a variety of organic reactions[4-7], biomedical applications and drug delivery systems[8], optoelectronic devices[9] and many others.

Product # Category Grade Particle Size (nm) Surface Area (m2/g) Pore Volume (cm3/g)

14-6100 Large (KCC-1 L1) ~900-1000 ~700 ~1.4

14-6110 Large (KCC-1 L2) ~900-1000 ~600 ~1.2

14-6120 Large (KCC-1 L3) ~900-1000 ~550 ~0.9

14-6200 Medium (KCC-1 M1) ~400-450 ~400 ~0.7

14-6210 Medium (KCC-1 M2) ~300-350 ~600 ~0.6

14-6300 Small (KCC-1 S1) ~130-190 ~380 ~0.8

References:1. Angew. Chem. Int. Ed. 2010, 49, 96522. Chem. Mater. 2015, 27, 82373. ACS Catalysis. 2016, 6, 27704. ChemSusChem 2012, 5, 855. Green Chem., 2016, 18, 5890 6. Angew. Chem. Int. Ed. 2011, 50, 27477. RSC Adv., 2017, 7, 248858. Langmuir 2014, 30, 108869. J. Mater. Chem. B, 2015, 3, 3201

14-611014-6110

a

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~600 m2/g, (KCC-1 L2) (112945‑52‑5) SiO2; FW: 60.09; white pwdr.; SA: ~600 m2/g; P.Vol. ~1.20 cm3/g Note: Diameter: ~900-1000nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. See 14-6100 (page 92)

14-612014-6120

a

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~550 m2/g (KCC-1 L3) (112945‑52‑5) SiO2; FW: 60.09; white pwdr.; SA: ~550 m2/g; P.Vol. ~0.97 cm3/g Note: Diameter: ~900-1000nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. See 14-6100 (page 92)

14-620014-6200

a

High Surface area Silica nanoparticles, medium, particle size ~400-450 nm, surface area ~400 m2/g, (KCC-1 M1) (112945‑52‑5) SiO2; FW: 60.09; white pwdr.; SA: ~400 m2/g; P.Vol. ~0.7 cm3/gNote: Diameter: ~400-450nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. See 14-6100 (page 92)

14-6100(cont.)

High Surface area Silica nanoparticles, large, particle size ~900-1000 nm, surface area ~700 m2/g, (KCC-1 L1) (112945‑52‑5)

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SILICON (Compounds)14-621014-6210

a

High Surface area Silica nanoparticles, medium, particle size ~300-350 nm, surface area ~600 m2/g, (KCC-1 M2) (112945‑52‑5) SiO2; FW: 60.09; white pwdr.; SA: ~600 m2/g; P.Vol. ~0.6 cm3/g Note: Diameter: ~300-350nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. See 14-6100 (page 92)

14-630014-6300

a

High Surface area Silica nanoparticles, small, particle size ~130-190 nm, surface area ~380 m2/g, (KCC-1 S1) (112945‑52‑5) SiO2; FW: 60.09; white to beige pwdr.; SA: ~380 m2/g; P.Vol. ~0.8 cm3/g Note: Diameter: ~130-190nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

Technical Note:1. See 14-6100 (page 92)

14-631014-6300

a

High Surface area Silica nanoparticles, small, particle size ~40-50 nm, surface area ~520 m2/g, (KCC-1 S2) (112945‑52‑5) SiO2; FW: 60.09; white to beige pwdr.; SA: ~520 m2/g; P.Vol. ~1.3 cm3/g Note: Diameter: ~40-50nm; This product is under license of patented Technology from King Abdullah University of Science and Technology – KAUST. Patent PCT/IB2010/002421.

1g 5g

14-144514-1445

aHAZ

Silicon(IV) bromide, (99.99% Si) PURATREM (7789‑66‑4) SiBr4; FW: 347.72; colorless liq.; m.p. 5.4º; b.p. 154º; d. 2.772 moisture sensitive

5g 25g

14-194314-1943

a

2,2,4,4-Tetramethyl-3,8,11,14,17-pentaoxa-2,4-disilaoctadecane, 99+% Electrolyte solvent ANL-2SM3 (855996‑83‑7) C15H36O5Si2; FW: 352.61; colorless liq. Note: Use for batteries for medical devices expressly excluded. U.S. Patent: 8,076,031 B1; 14/266,052.

5g 25g

Organosilicon Electrolytes for Lithium Ion Batteries 1. Silicon based electrolytes with polyethylene glycol oligomers improve thermal and electrochemical stability of lithium-ion batteries. 2. Increases battery long-term stability. 3. Are less flammable than conventional organic carbonate-based solvents and maintain the safe operation of batteries. 4. Improves conductivity and kinetics of the lithium salts.

Electrochemical and Physical Properties: 1. Disiloxane liquid electrolyte ANL-2SM3 exhibits electrochemical stability, high thermal stability, and low viscosity.- Viscosity 3.8 cP at 25ºC; The conductivity and viscosity of ANL-2SM3-based electrolyte are 3.65x10-4 Scm-1 and 18 cP at 25ºC [1,2] Charged cathode material is more thermally stable in the siloxane- based electrolyte than in the carbonate-based electrolyte [1]. Boiling point 269-271ºC; Glass transition temperature -103.0ºC 2. Soluble electrolytic lithium salts: LiBOB, LiPF6, ANL2SM3, and LiTFSIANL-2SM3 is compatible with nanostructured material-based electrodes [3]. 3. Disiloxane/LiBOB or Disiloxane /LiPF6 electrolytes show conductivities up to 6.2x10-4 Scm-1 at room temperature. Disiloxane electrolytes doped with 0.8MLiBOB are stable to 4.7 V. The LiBOB/disiloxane combinations were found to be good electrolytes for lithium-ion cells [4].References:

1. J. Power Sources, 2006, 160, 6452. J. Power Sources, 2006, 160, 13553. Chem. Mater., 2007, 19, 57344. J. Power Sources, 2010, 195, 6062

OO

MeSiOMe

OOMe SiMe3

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SILVER (Compounds)SILVER (Compounds)

47-257547-2575

a

[1,3-Bis[2,6-bis(i-propyl)phenyl]-2-imid-azolidinylidene]difluoromethylsilver(I) (1643366‑13‑5) C28H39AgF2N2; FW: 549.50; off-white pwdr. air sensitive, (store cold)

100mg500mg

Technical Notes:1. Catalyst for Pd(dba)2/DPPF assisted direct difluoromethylation

of aryl bromides and iodides.2. Pre-catalyst for copper assisted difluoromethylthiolation of aryl

and heteroaryl diazonium salts.3. Pre-catalyst for palladium assisted difluoromethylthiolation of pyridyl, quinolinyl, benzothiazolyl, thiophenyl,

carbazolyl and pyazolyl heteroaryl bromides, iodides, triflates and aryl iodides.

Pd(dba)2/DPPF; [(SiPr)AgCF2H]

NaOtBu (2 equiv)dioxane or toluene, 80 °C, 4–6 h

R R

X CF2H

X=Br, I

Tech. Note (1)Ref. (1)

[Cu(CH3CN)4]PF6/bpyR R

NaBF4 SCF2H[(SiPr)AgCF2H]+ S8

THF, RT[(SiPr)AgSCF2H] Tech. Note (2)

Ref. (2)

R

X

X=Br, I, OTf

Pd(dba)2/LigandR

SCF2H[(SiPr)AgCF2H]+ S8

THF, RT[(SiPr)AgSCF2H]

Ar = pyridyl, quinolinyl, benzothiazolyl, thiophenyl, carbazolyl, pyazolyl

Ar Ar Tech. Note (3)Ref. (3)

References:1. Nat. Commun. 2014, 5, 5405.2. Angew. Chem. Int. Ed. 2015, 54, 7648.3. Chem. Sci., 2016, 7, 3757.

SODIUM (Compounds) 11-114611-1146

a

Sodium hexafluorophosphate 99% (99.99%-Na) PURATREM (21324‑39‑0) F6NaP; FW: 167.95; white pwdr.; d. 2.37 air sensitive, moisture sensitive, hygroscopic

2g 10g

11-114711-1147

aHAZ

Sodium hexafluorophosphate 99% (99.99%-Na) PURATREM (<10ppm H2O) (21324‑39‑0) NaPF6; FW: 167.95; white pwdr. air sensitive, moisture sensitive, hygroscopic Note: Suitable for battery applications

1g 5g

11-101511-1015

a

Sodium tetrakis(4-fluorophenyl)borate dihydrate, 97% (207683‑22‑5) C24H20BF4NaO2; FW: 414.18(450.21); white xtl.

250mg 1g 5g

TITANIUM (Compounds)

N N

iPr

iPr

iPr

iPrAg

CF2H

Na+ PF6-

B-

F

F

F F

Na+

2 H2O

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TITANIUM (Compounds)22-107022-1070

a

Hexakis[μ-(2-amino-1,4-ben-zenedicarboxylato)][tetra-μ-hy-droxyocta-μ-oxooctatitanium], NH2-MIL-125(Ti), CONEKTIC™ T125 (1309760‑94‑8) C48H34N6O36Ti8; FW: 1653.74; yellow pwdr.; SA: ~1530; P.Vol. ~0.74 Note: Sold in collaboration with framergy for research purposes only. Patents: US8940392; EP2398812; JP5850750; KR101732623; CA2750746.

250mg1g

22-224022-2240

aHAZ

Tetrakis(dimethylamino)titanium(IV), 99% TDMAT (99.99%-Ti) PURATREM (3275‑24‑9) Ti[N(CH3)2]4; FW: 224.20; yellow to orange liq.; f.p. -22°F air sensitive, moisture sensitive

1g 5g 25g

VANADIUM (Compounds) 23-036523-0365

a

Tetrakis(ethylmethylamino)vanadium(IV), 98% TEMAV (791114‑66‑4) C12H32N4V; FW: 283.35; dark green liq. air sensitive, moisture sensitive

N(Et)Me

VMe(Et)N N(Et)Me

N(Et)Me

250mg 1g 5g

YTTERBIUM (Compounds) 70-013070-0130

a

Tris[N,N,N,N-tetramethylguanidinium][tris(1S)-(1,1’-binaphalene)-2,2’-diolato]ytterbate Yb-HTMG-B (1611526‑75‑0) C75H78N9O6Yb; FW: 1374.52; off-white to pale yellow pwdr. Note: U.S. Patent 14/898,925.

250mg 1g

Technical Note:1. See 57-1250 (page 43)

OO

Yb

OO

OO

NMe2

N NMe2+HH

Me2N

NMe2N + HH

NMe2

N

Me2N

HH+

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YTTRIUM (Compounds)YTTRIUM (Compounds)

39-585039-5850

a

Tris[N,N,N,N-tetramethylguanidinium][tris(1S)-(1,1’-binaphalene)-2,2’-diolato]yttrate Y-HTMG-B (1611526‑73‑8) C75H78N9O6Y; FW: 1290.39; orange pwdr. Note: U.S. Patent 14/898,925.

250mg1g

Technical Note:1. See 57-1250 (page 43)

ZIRCONIUM (Compounds) 98-404298-4042

aHAZ

Tetrakis(dimethylamino)zirconium(IV), 99% (99.99%-Zr) TDMAZ, 40-4115, contained in 50ml Swagelok® cylinder (96-1070) for CVD/ALD (19756‑04‑8) Zr[N(CH3)2]4; FW: 267.53; light yellow xtl. moisture sensitive, (store cold) Note: Product sold under, use subject to, terms and conditions of label license at www.strem.com/harvard1

25g

40-110940-1109

a

Zirconium aminobenzenedicarbox-ylate MOF (UiO-66-BDC-NH2, BDC-NH2:Zr=0.9-1.0) (1260119‑00‑3) Zr6O4(OH)4(C8H5NO4)x, X = 5.4-6.0; yellow solid; SA: 800-1075 m2/g; P.Vol. 0.31-0.41 cm3/g Note: Particle size: 0.1-0.5 micron, Thermal stability: 300ºC, Activation temperature: 150ºC Sold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

500mg2g

Technical Notes:1. Useful MOF for adsorption of CO2 applications1.2. Catalyst MOF used in the conversion of toxic

agents to non-toxic products2.References:

1. Carbon Dioxide Adsorption in Amine‑Functionalized Mixed‑Ligand Metal‑Organic Frameworks of UiO‑66 Topology., Chem.Sus.Chem. 2014.

2. Tailoring the Pore Size and Functionality of UiO-Type Metal−Organic Frameworks for Optimal Nerve Agent Destruction, Inorg. Chem. 2015.

3. Towards Metal‑Organic Framework based Field Effect Chemical Sensors: UiO‑66‑NH2 for Nerve Agent Detection, Chem. Sci., 2016, 7, 5827.

OO

Y

OO

OO

NMe2

N NMe2+HH

Me2N

NMe2N + HH

NMe2

N

Me2N

HH+

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ZIRCONIUM (Compounds)40-110840-1108

a

Zirconium benzenedicarboylate MOF (UiO-66-BDC, BDC:Zr=0.66-0.98) Zr6O4(OH)4(C8H4O4)x X = 3.96-5.88; white solid; SA: 1050-1400 m2/g; P.Vol. 0.42-0.58 cm3/g Note: Particle size: 0.2-0.5 micron, Thermal stability: 400ºC, Activation temperature: 300ºC Sold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

500mg2g

Technical Note:1. New zirconium-based inorganic building brick

that allows the synthesis of very high surface area MOF’s with unprecedented stability3.

References:1. Tuned to Perfection: Ironing Out the Defects in Metal−Organic Framework UiO-66 Chem. Mater. 2014, 26, 4068−4071.2. H2 storage in isostructural UiO‑67 and UiO‑66 MOFs Phys. Chem. Chem. Phys., 2012, 14, 1614–1626.3. A New Zirconium Inorganic Building Brick Forming Metal Organic Frameworks with Exceptional Stability. J.

Am. Chem. Soc. 2008, 130, 13850–13851.

40-111240-1112

a

Zirconium biphenyldicarboxyl-ate MOF (UiO-66-BPDC/UiO-67, BPDC:Zr=0.9-1.0) Zr6O4(OH)4(C14H8O4)x, X = 5.4-6.0; white solid; SA: 2400-2500 m2/g; P.Vol. 0.85-0.98 cm3/g moisture sensitive Note: Particle size: 0.4-0.7µ, Thermal stability: 450ºCSold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

250mg1g

Technical Notes:1. Metal−organic framework showing excellent

stability to water, reversible water vapor adsorption, and increased volumetric capacity for methane adsorption1

2. Remarkable stability at high temperatures, high pressures and in the presence of different

solvents, acids and bases2,3

References:1. UiO-67-type Metal−Organic Frameworks with Enhanced Water Stability and Methane Adsorption Capacity,

Inorg. Chem. 2016, 55, 1986−1991.2. H2 storage in isostructural UiO‑67 and UiO‑66 MOFs, Phys. Chem. Chem. Phys., 2012, 14, 1614–1626.3. A New Zirconium Inorganic Building Brick Forming Metal Organic Frameworks with Exceptional Stability. J.

Am. Chem. Soc. 2008, 130, 13850–13851, Jasmina Hafizovic Cavka, Søren Jakobsen, Unni Olsbye, Natha-lie Guillou, Carlo Lamberti, Silvia Bordiga, and Karl Petter Lillerud.

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ZIRCONIUM (Compounds)40-111440-1114

a

Zirconium Fumarate MOF (UiO-66-FA, FA:Zr=0.66-0.98) Zr6O4(OH)4(C4H2O4)x, X = 3.96-5.88; white solid; SA: 650-960 m2/g; P.Vol. 0.26-0.4 cm3/g Note: Particle size: 0.1-0.5 micron, Thermal stability: 200ºC, Activation temperature: 130ºC Sold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

500mg2g

Technical Notes:1. Metalorganic framework used in a large number of

studies for the storage of hydrogen or methane2

2. Water adsorption in MOF’s for many applications such as dehumidification, thermal batteries, and delivery of drinking water in remote areas3

References:1. Water harvesting from air with metal‑organic frameworks powered by natural sunlight. Science, 2017, 356,

430–434.2. A Facile “Green” Route for Scalable Batch Production and Continuous Synthesis of Zirconium MOFs. Eur.

J. Inorg. Chem. 2016, 4490–4498. 3. Water Adsorption in Porous Metal−Organic Frameworks and Related Materials, J. Am. Chem. Soc., 2014,

136, 4369−4381.4. A water‑born Zr‑based porous coordination polymer: Modulated synthesis of Zr‑fumarate MOF. Microporous

and mesoporous materials , 2015, 203,186-194.

40-110640-1106

a

Zirconium trans-1, 2-ethylenedicarboxylic acid MOF (UiO-66-FA, FA:Zr=1) Zr6O4(OH)4(C4H2O4)6; cream solid; SA: 720-770 m2/g; P.Vol. 0.29-0.32 cm3/g Note: Particle size: 0.1-0.5 micron, Thermal stability: 200ºC, Activation temperature: 150ºC Sold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

500mg2g

Technical Notes:1. Metalorganic framework used in a large number of studies for the storage of hydrogen or methane2

2. Water adsorption in MOF’s for many applications such as dehumidification, thermal batteries, and delivery of drinking water in remote areas3

References:1. Water harvesting from air with metal‑organic frameworks powered by natural sunlight. Science, 2017, 356,

430–434.2. A Facile “Green” Route for Scalable Batch Production and Continuous Synthesis of Zirconium MOFs. Eur.

J. Inorg. Chem. 2016, 4490–4498. 3. Water Adsorption in Porous Metal−Organic Frameworks and Related Materials, J. Am. Chem. Soc., 2014,

136, 4369−4381.4. A water‑born Zr‑based porous coordination polymer: Modulated synthesis of Zr‑fumarate MOF. Microporous

and mesoporous materials , 2015, 203,186-194.

COOH

COOH

Zr OO

HO

OH

ZrZr

Zr Zr

O

ZrHO

O

OH

O O

OO

O

O

O

O

COOHHOOC

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ZIRCONIUM (Compounds)40-111140-1111

a

Zirconium trimellitate MOF (UiO-66-BDC-COOH, BDC-COOH:Zr=0.9-1.0) Zr6O4(OH)4(C9H4O6)x, X = 5.4-6.0; white solid; SA: 550-600 m2/g; P.Vol. 0.25-0.27 cm3/g Note: Particle size: 0.2-0.5 micron, Thermal stability: 350ºC, Activation temperature: 150ºCSold under license from Inven2 AS for research purposes only. PCT/GB2009/001087.

500mg2g

Technical Notes:1. MOF for which the introduction of copper

markedly increases ammonia adsorption capacities1

2. Functionalized forms show the highest selectivity, good working capacity and medium ranged CO2 adsorption enthalpy that make these materials very promising for physi-sorption-based processes2

References:1. Engineering Copper Carboxylate Functionalities on Water Stable Metal−Organic Frameworks for

Enhancement of Ammonia Removal Capacities. J. Phys. Chem. C, 2017, 121, 3310−3319.2. Functionalizing porous zirconium terephthalate UiO‑66(Zr) for natural gas upgrading: a computational

exploration., Chem. Commun., 2011, 47, 9603–9605.

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KITS - AntPhos and WingPhos KitKITS (Compounds)

96-381096-3810 AntPhos and WingPhos Kit Sold in collaboration with Zejun for research purposes only. Patents ZL201310020371.1, CN 201610056390. Components also available for individual sale.Contains the following:

P

O

tBu

15-1960 25mg

P

O

tBu

15-1963 25mg

P

O

tBu

15-1967 25mg

P

O

H

P

O

H

tBu

tBu

15-1970 25mg

P

O

H

P

O

H

tBu

tBu

15-1975 25mg

15-1960 4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydrobenzo[d][1,3]

oxaphosphole, 98+% rac-AntPhos (1268693‑24‑8)25mg See page 66

15-1963 (R)-4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphole,98+% (>99% ee) [(R)-AntPhos] (1456816‑37‑7)

25mg See page 66

15-1967 (S)-4-(Anthracen-9-yl)-3-(t-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphole,99+% (>99% ee) [(S)-AntPhos] (1807740‑34‑6)

25mg See page 67

15-1970 (2R,2’R,3R,3’R)-4,4’-Di(anthracen-9-yl)-3,3’-di-t-butyl-2,2’,3,3’-tetrahydro-2,2’-bibenzo[d][1,3]oxaphosphole, min 98% (>90% ee), [(2R,2’R,3R,3’R)-WingPhos] (1884680‑45‑8)

25mg See page 73

15-1975 (2S,2’S,3S,3’S)-4,4’-Di(anthracen-9-yl)-3,3’-di-t-butyl-2,2’,3,3’-tetrahydro-2,2’-bibenzo[d][1,3]oxaphosphole, min 98%, (>99% ee), [(2S,2’S,3S,3’S)-WingPhos] (1435940‑19‑4)

25mg See page 73

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KITS - BI-DIME Ligand Kit96-065096-0650

a

BI-DIME Ligand Kit Sold in collaboration with Zejun for research purposes only. Patents: ZL2013105048267, CN104558038. Components also available for individual sale.Contains the following:

P

O

MeO OMetBu

15-6205 25mg

P

O

MeO OMetBu

15-6210 25mg

P

O

MeO OMetBu

15-6211 25mg

P

O

MeO OMetBu

Me

15-6220 25mg

P

O

MeO OMetBu

Me

15-6225 25mg

P

O

MeO OMetBu

iPr

15-6230 25mg

P

O

MeO OMetBu

iPr

15-6235 25mg

15-6205 3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d]

[1,3]oxaphosphole, min. 97% rac-BI-DIME (1246888‑90‑3)25mg See page 70

15-6210 (S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% (S)-BI-DIME (1373432‑09‑7)

25mg See page 72

15-6211 (R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole, min. 97% (R)-BI-DIME (1373432‑03‑7)

25mg See page 71

15-6220 (2S,3S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-methyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (S,S)-Me-BI-DIME (1373432‑11‑1)

25mg See page 72

15-6225 (2R,3R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-methyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (R,R)-Me-BI-DIME (1477517‑18‑2)

25mg See page 72

15-6230 (2S,3S)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-i-propyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (S,S)-iPr-BI-DIME (1477517‑21‑7)

25mg See page 72

15-6235 (2R,3R)-3-(t-Butyl)-4-(2,6-dimethoxyphenyl)-2-i-propyl-2,3-di-hydrobenzo[d][1,3]oxaphosphole, min. 97% (R,R)-iPr-BI-DIME (1477517‑19‑3)

25mg See page 72

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - Buchwald Biaryl Phosphine Ligand Mini Kit 396-549596-5495

a

Buchwald Biaryl Phosphine Ligand Mini Kit 3 for Aromatic Carbon-Heteroatom Bond Formation, Suzuki Coupling and Negishi Cross-coupling For aromatic carbon-heteroatom bond formation and Suzuki Coupling. Patents: US 6,395,916, US 6,307,087. Components also available for individual sale.Contains the following:

Me

MeiPriPr

iPr

P(tBu)2

OMeMe(OMe)

(Me)

15-1063 250mg

PCy2

tBu OMe

tBu

15-1105 250mg

PPh2

NMe2Me2N

15-1125 100mg

iPriPr

SO3Na

PCy2

15-1135 100mg

PCy2

OMeMeO

SO3Na

15-1142 500mg

PCy2

NMe2Me2N

15-1147 250mg

PEt2NMe2Me2N

2HBF4

15-1151 100mg

PCy2

NMe2

15-1154 250mg

OMe

MeiPriPr

iPr

P(tBu)2

15-1168 100mg

PAd2

OMe

iPriPr

iPrnBu

FF

FF

15-2065 100mg

NMe2Me2N

PtBu

Ph

15-3010 250mg

P

CF3

CF3 2NMe2Me2N

OMe

MeO

15-3015 100mg

P

CF3

CF32O(iPr)(iPr)O

OMe

MeO

15-3020 250mg

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - Buchwald Biaryl Phosphine Ligand Mini Kit 3

15-1063 2-Di-t-butylphosphino-4-methoxy-3,5,6-trimethyl-2’,4’,6’-tri-i-propyl)-1,1’-biphenyl, min. 98% [~1:1 mixture with regioisomer, 2-Di-t-butylphosphino-5-me-thoxy-3,4,6-trimethyl-2’,4’,6’-tri-i-propylbiphenyl] (1359986‑21‑2)

250mg Visit strem.com

15-1105 2-Dicyclohexylphosphino-2’-methoxy-4’,6’-di-t-butyl-1,1’-bi-phenyl, min. 98% VPhos (1848244‑75‑6)

250mg Visit strem.com

15-1125 2-Diphenylphosphino-2’,6’-bis(dimethylamino)-1,1’-biphe-nyl, min. 98% PhCPhos (1447963‑71‑4)

100mg Visit strem.com

15-1135 2’-Dicyclohexylphosphino-2,6-di-i-propyl-4-sulfona-to-1,1’-biphenyl hydrate sodium salt (XPhos-SO3Na) (870245‑84‑4)

100mg Visit strem.com

15-1142 2’-Dicyclohexylphosphino-2,6-dimethoxy-3-sulfona-to-1,1’-biphenyl hydrate sodium salt (water soluble SPhos), min. 98% (1049726‑96‑6)

500mg Visit strem.com

15-1147 2-Dicyclohexylphosphino-2’,6’-bis(dimethylamino)-1,1’-bi-phenyl, min. 98% CPhos (1160556‑64‑8)

250mg Visit strem.com

15-1151 2-Diethylphosphino-2’,6’-bis(dimethylamino)-1,1’-biphenyl di(hydrogen tetrafluoroborate) salt, min. 98% EtCPhos

100mg Visit strem.com

15-1154 2-Dicyclohexylphosphino-4’-(N,N-dimethylamino)-1,1’-bi-phenyl, 98% (1185899‑00‑6)

250mg Visit strem.com

15-1168 2-(Di-t-butylphosphino)-3-methoxy-6-methyl-2’,4’,6’-tri-i-propyl-1,1’-biphenyl, min. 98% RockPhos (1262046‑34‑3)

100mg Visit strem.com

15-2065 2-(Diadamantylphosphino)-3-methoxy-2’,4’,6’-tri-i-pro-pyl-3’-(2,3,5,6-tetrafluoro-4-butylphenyl)-1,1’-biphenyl, AlPhos (1805783‑60‑1)

100mg Visit strem.com

15-3010 2-(t-Butylphenylphosphino)-2’,6’-dimethylamino-1,1’-biphenyl, 98% (t-Bu)PhCPhos (1660153‑91‑2)

250mg Visit strem.com

15-3015 2-[Bis(3,5-trifluoromethylphenylphosphino)-3,6-dime-thoxy]-2’,6’-dimethylamino-1,1’-biphenyl, 98% (1810068‑30‑4)

100mg Visit strem.com

15-3020 2-[Bis(3,5-trifluoromethylphenylphosphino)-3,6-dime-thoxy]-2’,6’-di-i-propoxy-1,1’-biphenyl, 98% (1810068‑31‑5)

250mg Visit strem.com

96-5495(cont.)

Buchwald Biaryl Phosphine Ligand Mini Kit 3 for Aromatic Carbon-Heteroatom Bond Formation, Suzuki Coupling and Negishi Cross-coupling For aromatic carbon-heteroatom bond formation and Suzuki Coupling.

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - Buchwald Palladacycle Precatalyst Kit 2b96-550696-5506

a

Buchwald Palladacycle Precatalyst Kit 2b (Methanesulfonato-2’-amino-1,1’-biphenyl-2-yl- Palladacycles Gen. 3) Patents: US 6,395,916, US 6,307,087. Components also available for individual sale.Contains the following:

PdH2N OMs

NMe2

Me2N PEt2

46-0348 50mg

PdH2N OMs

(tBu)2P

46-0357 100mg

PdH2N OMs

P(tBu)3

46-0387 250mg

PPh

O

O

O

MeMe

MeMe

H2N Pd OMs

46-0392 500mg

PdH2N OMs

NMe2

Me2N PCy2

46-0487 100mg

PdH2N OMs

NO PAd2

46-0935 250mg

PdH2N OMs

PPh2

N

O

PPh2

H

46-0959 100mg

PdH2N OMs

PPh2

Fe PPh2

46-2128 250mg

PdH2N OMs

Me2N P(tBu)2

46-2135 250mg

PdH2N OMs

Ph2P PPh2

46-2153 250mg

PdH2N OMs

P(tBu)2

Fe P(tBu)2

46-2158 250mg

PdH2N OMs

P(tBu)2

iPr

iPr

iPr

Me Me

Me

Me

46-2163 100mg

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KITS - Buchwald Palladacycle Precatalyst Kit 2b

46-0348 Methanesulfonato[2-diethylphosphino-2’,6’-bis(dimethyl-amino)-1,1-biphenyl](2’-amino-1,1’-biphenyl-2-yl)palladi-um(II), min. 98% [EtCPhos Palladacycle Gen. 3]

50mg Visit strem.com

46-0357 Methanesulfonato(2-di-t-butylphosphino-1,1’-binaphthyl)(2’-amino-1,1’-biphenyl-2-yl)palladium(II), min. 95% [TrixiePhos Palladacycle Gen. 3]

100mg Visit strem.com

46-0387 Methanesulfonato(tri-t-butylphosphino)(2’-amino-1,1’-biphe-nyl-2-yl)palladium(II), 98% [P(t-Bu)3 Palladacycle Gen. 3] (1445086‑17‑8)

250mg Visit strem.com

46-0392 Methanesulfonato(1,3,5,7-tetramethyl-8-phenyl-2,4,6-tri-oxa-8-phosphaadamantane)(2’-amino-1,1’-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [MeCgPPh Palladacycle Gen. 3]

500mg Visit strem.com

46-0487 Methanesulfonato(2-dicyclohexylphosphino-2’,6’-bis(dimethy-lamino)-1,1’-biphenyl)(2’-amino-1,1’-biphenyl-2-yl)palladium(II), 98% [CPhos Palladacycle Gen. 3] (1447963‑73‑6)

100mg Visit strem.com

46-0935 Methanesulfonato{N-[2-(di-1-adamantylphosphino)phenyl]morpholine}(2’-amino-1,1’-biphenyl-2-yl)palladium(II) dichloro-methane adduct, min. 98% [Mor-Dalphos Palladacycle Gen. 3]

250mg See page 64

46-0959 Methanesulfonato[4,6-bis(diphenylphosphino)phenoxazine](2’-amino-1,1’-biphenyl-2-yl)palladium(II), 98% [NiXantphos Palladacycle Gen. 3] (1602922‑03‑1)

100mg Visit strem.com

46-2128 Methanesulfonato[1,1’-bis(diphenylphosphino)ferrocene)](2’-amino-1,1’-biphenyl-2-yl)palladium(II), min. 98% [DPPF Palladacycle Gen. 3] (1445086‑28‑1)

250mg Visit strem.com

46-2135 Methanesulfonato[2-(di-t-butylphosphino)-2’-(N,N-dimeth-ylamino)-1,1’-biphenyl](2’-amino-1,1’-biphenyl-2-yl)palladi-um(II) dichloromethane adduct, min. 98% [t-BuDavePhos Palladacycle Gen. 3] (1445085‑92‑6)

250mg Visit strem.com

46-2153 Methanesulfonato[2,2’-bis(diphenylphosphino)-1,1’-binaph-thyl](2’-amino-1,1’-biphenyl-2-yl)palladium(II), min. 98% [BINAP Palladacycle Gen. 3]

250mg Visit strem.com

46-2158 Methanesulfonato(1,1’-bis(di-t-butylphosphino)ferrocene)(2’-amino-1,1’-biphenyl-2-yl)palladium(II), min. 98% [DTBPF Palladacycle Gen. 3]

250mg Visit strem.com

46-2163 Methanesulfonato(2-di-t-butylphosphino-3,4,5,6-tetrameth-yl-2’,4’,6’-tri-i-propylbiphenyl)(2’-amino-1,1’-biphenyl-2-yl)palladium(II), min. 95% [Me4 t-ButylXPhos Palladacycle Gen. 3] (1507403‑85‑1)

100mg Visit strem.com

96-5506(cont.)

Buchwald Palladacycle Precatalyst Kit 2b (Methanesulfonato-2’-amino-1,1’-biphenyl-2-yl- Palladacycles Gen. 3)

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - CalB immo KIT™ - Immobilized enzyme96-405096-4050

a

CalB immo KIT™ - Immobilized enzyme Store in dry conditions (2-8°C). Do not freeze. Shelf Life: 1 year; Sold in collaboration with Purolite for research purposes only. Components also available for individual sale.Contains the following:

07-3130 CalB immo Plus™ - Immobilized enzyme 10g See page 2707-3142 CalB immo 8285™ - Immobilized enzyme 10g See page 2707-3148 CalB immo 8806™ - Immobilized enzyme 10g See page 2707-3152 CalB immo 5587™ - Immobilized enzyme 10g See page 2607-3155 CalB immo 1090™ - Immobilized enzyme 10g See page 2607-3159 CalB immo 5872™ - Immobilized enzyme 10g See page 26

Item # Immobilized on Immobilization Enzyme activity (PLU/g dry)

07-3130 DVB/methacrylate Adsorption >9,000

07-3142 Epoxy/butyl methacrylate Covelent >10,000

07-3148 Octadecyl methacrylate Adsorption >10,000

07-3152 Styrene/DVB copolymer Adsorption >4,000

07-3155 Macroporous styrene/DVB Adsorption >8,000

07-3159 Styrene/DVB Adsorption >3,500

Appearance: White to slightly yellow spherical beads, free from foreign matterPricipal Applications: Screening of immobilized lipases for process development, Esterifi cations (regio- and stereo-se-lective), Transesterfi cation, Amidation, Fats and oils modifi cationAdvantages: Fast screening in process development, Wide selection of enzyme carriers for different applications

KITS - Enzyme Carrier Lifetech™ ECRKIT1 96-025596-0255

a

Enzyme carrier Lifetech™ ECRKIT1 Store in dry conditions (2-20°C). Do not freeze. Shelf Life: 5 years; This enzyme carrier kit allows rapid screening of different methods of enzyme immobilization. Sold in collaboration with Purolite for research purposes only. Components also available for individual sale.Contains the following:

06-0810 Enzyme carrier Lifetech™ ECR8204F 50g See page 2906-0828 Enzyme carrier Lifetech™ ECR8285 50g See page 3306-0913 Enzyme carrier Lifetech™ ECR1090M 50g See page 2906-0925 Enzyme carrier Lifetech™ ECR1030M 50g See page 2707-1512 Enzyme carrier Lifetech™ ECR8309F 50g See page 3007-1532 Enzyme carrier Lifetech™ ECR8806F 50g See page 32

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - Graphene Quantum Dots (GQDs) Master Kit96-741096-7410

a

Graphene Quantum Dots (GQDs) Master Kit Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK. Components also available for individual sale.Contains the following:

06-0330 Graphene Quantum Dots (GQDs), Aqua-Green

Luminescent (1034343‑98‑0)100mg See page 48

06-0332 Graphene Quantum Dots (GQDs) in water, Aqua-Green Luminescent (1034343‑98‑0)

100ml See page 48

06-0334 Graphene Quantum Dots (GQDs), Blue Luminescent (1034343‑98‑0)

100mg See page 49

06-0336 Graphene Quantum Dots (GQDs) in water, Blue Luminescent (1034343‑98‑0)

100ml See page 49

06-0340 Graphene Quantum Dots (GQDs) in water, Cyan Luminescent (1034343‑98‑0)

100ml See page 49

Item #Photoluminescence

QY+ * λ max * Max emission FWHM *

06-0330 / 06-0332 >17% 485 nm 525 nm 70 nm

06-0334 / 06-0336 >65% 350 nm 445 nm 65 nm

06-0340 >25% 420 nm 490 nm 80 nm

Particle diameter: <5 nmTopographic height: 1.0 - 2.0 nmConcentration: 1mg/ml (for liquid items)

Abbreviations: QY+ = Quantum Yield; λ max = Maximum excitation wavelength; FWHM = Full width at half maximum

KITS - Graphene Quantum Dots (GQDs) Mini Kit (Powders) 96-742596-7425

a

Graphene Quantum Dots (GQDs) Mini Kit (Powders) Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK. Components also available for individual sale.Contains the following:

06-0330 Graphene Quantum Dots (GQDs), Aqua-Green Luminescent

(1034343‑98‑0)100mg See page 48

06-0334 Graphene Quantum Dots (GQDs), Blue Luminescent (1034343‑98‑0)

100mg See page 49

Item # Color & FormPhotoluminescence

QY+ * λ max * Max emission FWHM *

06-0330 dark red-brown pwdr. >17% 485 nm 525 nm 70 nm

06-0334 dark brown pwdr. >65% 350 nm 445 nm 65 nm

Particle diameter: <5 nmTopographic height: 1.0 - 2.0 nm

Abbreviations: QY+ = Quantum Yield; λ max = Maximum excitation wavelength; FWHM = Full width at half maximum

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - Graphene Quantum Dots in water (GQDs) Mini Kit (Liquids)96-742096-7420

a

Graphene Quantum Dots in water (GQDs) Mini Kit (Liquids) Sold in collaboration with Dotz Nano Ltd. for research purposes only. Suggested use within 6 months of purchase. Do not freeze. Store in DARK. Components also available for individual sale.Contains the following:

06-0332 Graphene Quantum Dots (GQDs) in water, Aqua-Green

Luminescent (1034343‑98‑0)100ml See page 48

06-0336 Graphene Quantum Dots (GQDs) in water, Blue Luminescent (1034343‑98‑0)

100ml See page 49

06-0340 Graphene Quantum Dots (GQDs) in water, Cyan Luminescent (1034343‑98‑0)

100ml See page 49

Item # Color & FormPhotoluminescence

QY+ * λ max * Max emission FWHM *

06-0332 cloudy orange liq. >17% 485 nm 525 nm 70 nm

06-0336 cloudy colorless liq. >65% 350 nm 445 nm 65 nm

06-0340 cloudy brown liq. >25% 420 nm 490 nm 80 nm

Particle diameter: <5 nmTopographic height: 1.0 - 2.0 nmConcentration: 1mg/ml

Abbreviations: QY+ = Quantum Yield; λ max = Maximum excitation wavelength; FWHM = Full width at half maximum

KITS - Lipase immo Kit - Immobilized enzymes96-406596-4065

a

Lipase immo Kit - Immobilized enzymes The KIT contains 10g of each of the following:- CalB immo Plus™(Lipase from Candida antarctica B)*07-3130*- CalA immo (Lipase from Candida antarctica A)- TL immo (Lipase from Thermomyces lanuginosa)- RM immo (Lipase from Rhizomucor miehei)- CR immo (Lipase from Candida rugosa)- PS immo (Lipase from Pseudomonas cepacia)

A selection of immobilized lipases on different Lifetech™ ECR enzyme carrier resins for screening purposes. Store in dry conditions (2-8°C). Do not freeze.Sold in collaboration with Purolite for research purposes only. Components also available for individual sale.Contains the following:

Pricipal Applications: Esterifications (regio - and stereo-selective), Transesterfication, Kinetic resolution of racemic alcohols, amines, esters and triacylclycerides, Fats and oils modification, Hydrolysis of esters

Advantages: Fast screening in process development, Wide selection of immobilized lipases, Optimal for all applictions in organic solvents.

New Products Introduced Since Chemiker XXIX (July 2016)

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KITS - Solvias Josiphos Nickel Catalyst Kit96-366096-3660

a

Solvias Josiphos Nickel Catalyst Kit Sold in collaboration with Solvias for research purposes only. Components also available for individual sale.Contains the following:

P

P(tBu)2

NiFe

Ph

PhCl CN

Me

28-0170 100mg

P

PCy2

NiFe

Cy

CyCl CN

Me

28-0172 100mg

P

PPh2

NiFe

Cy

CyCl CN

Me

28-0175 100mg

P

P(tBu)2

NiFe

CN

Me

FF

Cl

28-0178 100mg

28-0170 Chloro(4-cyanophenyl){(R)-1-[(S)-2-(diphenylphosphino)

ferrocenyl]ethyl(di-t-butyl)phosphine} nickel(II) (2049086‑34‑0)

100mg See page 51

28-0172 Chloro(4-cyanophenyl){(R)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyl (dicyclohexylphosphine)}nickel(II) (2049086‑35‑1)

100mg See page 50

28-0175 Chloro(4-cyanophenyl){(R)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyl (diphenylphosphine)}nickel(II) (2049086‑36‑2)

100mg See page 51

28-0178 Chloro(4-cyanophenyl){(R)-1-[(S)-2-(bis(4-fluorophenyl)phosphinoferrocenyl]ethyl(di-t-butylphosphine)}nickel(II) (2049086‑37‑3)

100mg See page 50

Visit strem.com for the following:

▪ New Product Announcements▪ Searchable Catalog▪ Technical Notes▪ Safety Data Sheets (SDS)▪ Certificates of Analysis (CofA)▪ Product Pricing and Availability

If you are unable to find a product you need please contact us.

Custom synthesis services are available.

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© 2017 Strem Chemicals, Inc.

The Strem Product Line

Strem Chemicals, Inc.7 Mulliken WayDexter Industrial ParkNewburyport, MA 01950-4098U.S.A.

Office Tel: (978) 499-1600Office Fax: (978) 465-3104

Toll-free (U.S. & Canada)Tel: (800) 647-8736Fax: (800) 517-8736

Email: info@strem.comwww.strem.com

Strem Chemicals, Inc.15, rue de l’AtomeZone IndustrielleF-67800 BISCHHEIM (France)Tel.: +33 (0) 3 88 62 52 60Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals, Inc.Postfach 1215D-77672 KEHL, GermanyTel.: +49 (0) 7851 75879Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals UK, Ltd.An Independent Distributor of Strem Chemicals ProductsNewton Hall, Town StreetNewton, Cambridge, CB22 7ZE, UKTel.: 0845 643 7263Fax: 0845 643 7362Email: enquiries@strem.co.uk

OUR LINE OF RESEARCH CHEMICALSBiocatalysts & Organocatalysts Electronic Grade ChemicalsFullerenesHigh Purity Inorganics & Alkali MetalsIonic LiquidsLigands & Chiral LigandsMetal Acetates & CarbonatesMetal Alkoxides & beta-DiketonatesMetal Alkyls & AlkylamidesMetal Carbonyls & DerivativesMetal Catalysts & Chiral CatalystsMetal Foils, Wires, Powders & ElementsMetal Halides, Hydrides & DeuteridesMetal Oxides, Nitrates, ChalcogenidesMetal ScavengersMetallocenesNanomaterialsOrganofluorinesOrganometallicsOrganophosphines & ArsinesPorphines & PhthalocyaninesPrecious Metal & Rare Earth ChemicalsVolatile Precursors for MOCVD, CVD & ALD

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© 2017 Strem Chemicals, Inc.

The Strem Product Line

Strem Chemicals, Inc.7 Mulliken WayDexter Industrial ParkNewburyport, MA 01950-4098U.S.A.

Office Tel: (978) 499-1600Office Fax: (978) 465-3104

Toll-free (U.S. & Canada)Tel: (800) 647-8736Fax: (800) 517-8736

Email: info@strem.comwww.strem.com

Strem Chemicals, Inc.15, rue de l’AtomeZone IndustrielleF-67800 BISCHHEIM (France)Tel.: +33 (0) 3 88 62 52 60Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals, Inc.Postfach 1215D-77672 KEHL, GermanyTel.: +49 (0) 7851 75879Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals UK, Ltd.An Independent Distributor of Strem Chemicals ProductsNewton Hall, Town StreetNewton, Cambridge, CB22 7ZE, UKTel.: 0845 643 7263Fax: 0845 643 7362Email: enquiries@strem.co.uk

OUR LINE OF RESEARCH CHEMICALSBiocatalysts & Organocatalysts Electronic Grade ChemicalsFullerenesHigh Purity Inorganics & Alkali MetalsIonic LiquidsLigands & Chiral LigandsMetal Acetates & CarbonatesMetal Alkoxides & beta-DiketonatesMetal Alkyls & AlkylamidesMetal Carbonyls & DerivativesMetal Catalysts & Chiral CatalystsMetal Foils, Wires, Powders & ElementsMetal Halides, Hydrides & DeuteridesMetal Oxides, Nitrates, ChalcogenidesMetal ScavengersMetallocenesNanomaterialsOrganofluorinesOrganometallicsOrganophosphines & ArsinesPorphines & PhthalocyaninesPrecious Metal & Rare Earth ChemicalsVolatile Precursors for MOCVD, CVD & ALD

Custom Synthesis

cGMP Facilities

FDA Inspected

Drug Master Files

Complete Documentation

MOF

© 2017 Strem Chemicals, Inc.

The Strem Product Line

Strem Chemicals, Inc.7 Mulliken WayDexter Industrial ParkNewburyport, MA 01950-4098U.S.A.

Office Tel: (978) 499-1600Office Fax: (978) 465-3104

Toll-free (U.S. & Canada)Tel: (800) 647-8736Fax: (800) 517-8736

Email: info@strem.comwww.strem.com

Strem Chemicals, Inc.15, rue de l’AtomeZone IndustrielleF-67800 BISCHHEIM (France)Tel.: +33 (0) 3 88 62 52 60Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals, Inc.Postfach 1215D-77672 KEHL, GermanyTel.: +49 (0) 7851 75879Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals UK, Ltd.An Independent Distributor of Strem Chemicals ProductsNewton Hall, Town StreetNewton, Cambridge, CB22 7ZE, UKTel.: 0845 643 7263Fax: 0845 643 7362Email: enquiries@strem.co.uk

OUR LINE OF RESEARCH CHEMICALSBiocatalysts & Organocatalysts Electronic Grade ChemicalsFullerenesHigh Purity Inorganics & Alkali MetalsIonic LiquidsLigands & Chiral LigandsMetal Acetates & CarbonatesMetal Alkoxides & beta-DiketonatesMetal Alkyls & AlkylamidesMetal Carbonyls & DerivativesMetal Catalysts & Chiral CatalystsMetal Foils, Wires, Powders & ElementsMetal Halides, Hydrides & DeuteridesMetal Oxides, Nitrates, ChalcogenidesMetal ScavengersMetallocenesNanomaterialsOrganofluorinesOrganometallicsOrganophosphines & ArsinesPorphines & PhthalocyaninesPrecious Metal & Rare Earth ChemicalsVolatile Precursors for MOCVD, CVD & ALD

Custom Synthesis

cGMP Facilities

FDA Inspected

Drug Master Files

Complete Documentation

Metal Organic Frameworks

and Ligands for MOF Synthesis

CARBON

© 2017 Strem Chemicals, Inc.

The Strem Product Line

Strem Chemicals, Inc.7 Mulliken WayDexter Industrial ParkNewburyport, MA 01950-4098U.S.A.

Office Tel: (978) 499-1600Office Fax: (978) 465-3104

Toll-free (U.S. & Canada)Tel: (800) 647-8736Fax: (800) 517-8736

Email: info@strem.comwww.strem.com

Strem Chemicals, Inc.15, rue de l’AtomeZone IndustrielleF-67800 BISCHHEIM (France)Tel.: +33 (0) 3 88 62 52 60Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals, Inc.Postfach 1215D-77672 KEHL, GermanyTel.: +49 (0) 7851 75879Fax: +33 (0) 3 88 62 26 81Email: info.europe@strem.com

Strem Chemicals UK, Ltd.An Independent Distributor of Strem Chemicals ProductsNewton Hall, Town StreetNewton, Cambridge, CB22 7ZE, UKTel.: 0845 643 7263Fax: 0845 643 7362Email: enquiries@strem.co.uk

OUR LINE OF RESEARCH CHEMICALSBiocatalysts & Organocatalysts Electronic Grade ChemicalsFullerenesHigh Purity Inorganics & Alkali MetalsIonic LiquidsLigands & Chiral LigandsMetal Acetates & CarbonatesMetal Alkoxides & beta-DiketonatesMetal Alkyls & AlkylamidesMetal Carbonyls & DerivativesMetal Catalysts & Chiral CatalystsMetal Foils, Wires, Powders & ElementsMetal Halides, Hydrides & DeuteridesMetal Oxides, Nitrates, ChalcogenidesMetal ScavengersMetallocenesNanomaterialsOrganofluorinesOrganometallicsOrganophosphines & ArsinesPorphines & PhthalocyaninesPrecious Metal & Rare Earth ChemicalsVolatile Precursors for MOCVD, CVD & ALD

Custom Synthesis

cGMP Facilities

FDA Inspected

Drug Master Files

Complete Documentation

Carbon-Based Nanomaterials & Elemental Forms

Carbon Nanotubes, Graphene – Powder,

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