A Novel Fat Removal Tool for Human Tissue Brandon Boles, Audrey Guyer, Ryan Mitchell, Krunal Parikh,...
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A Novel Fat Removal Tool for Human Tissue Brandon Boles, Audrey Guyer, Ryan Mitchell, Krunal Parikh, Matthew Ringer Overview Background Information The
A Novel Fat Removal Tool for Human Tissue Brandon Boles, Audrey
Guyer, Ryan Mitchell, Krunal Parikh, Matthew Ringer Overview
Background Information The Product LifeCell aims to alleviate
safety concerns and improve the uniformity of their final allograft
products by implementing a new fat removal system to replace the
use of scalpels. Project Scope The scope of the project is to
develop a functional prototype to remove adipose tissue from the
dermal layer of donated human skin while also promoting technician
safety and increasing functionality over the current process. Final
Design Concept Generation Testing Plan Acknowledgements Testing of
the final design was completed by the senior design team and
technicians at LifeCell. The final design was used in removing
adipose tissue from human skin, and the new design was rated
against the current scalpel method for each metric. Metrics
LifeCell Corporation processes donated human skin tissue into
allografts to be used in surgeries. Currently, scalpels (see Figure
1) are used to remove the fat layer from the dermis before further
processing takes place. The current technique leads to a
non-uniform product and worker injury. We would like to thank our
sponsor, LifeCell Corporation, our advisor Dr. Anita Singh, as well
as Mr. Beard and the rest of the Senior Design Staff. Prototype The
final design is an 18,000 rpm motor with a torque rating of 771 g-
cm. It is powered by 3-6 V of rechargeable batteries that are in
circuit with a safety toggle switch and trigger button to initiate
blade movement. Concept Selection Design Process First Generation
This prototype featured a permanently installed stainless steel
blade on the Remington HC5550. The prototype was tested on pork
belly (Figure 3) to simulate donated human skin, as highlighted in
green, and it was compared to a static blade (red). Second
Generation This prototype featured a removable stainless steel
razor blade held in place by a 3-pin system. A blade guard made of
Delrin was installed above the blade mechanism to prevent adipose
tissue from entering the device. This prototype was also tested on
pork belly, as seen in Figure 4. Third Generation This prototype
incorporated a trigger button mechanism to increase control and
minimize potential harm to the technicians. This prototype was
tested on human tissue at LifeCell in Branchburg, New Jersey (see
Figure 5). Fourth Generation This prototype incorporated a modified
stainless steel bumper below the blade in order to minimize the
possibility of human error in terms of inflicting dermal damage
during fat removal. As well, this prototype used a blade with
curved edges to promote cutting. Validation MetricConstraint
Technician Incidents: No puncture wounds Safety Technician Fatigue:
50% reduction Safety Fat Removal: 100 % fat removal Functionality
Dermal damage: 80% reduction Functionality Cost: $20 disposable
costCost-efficient In order for the design to be implemented, it
must be superior in comparison to the current scalpel technique. A
qualitative feedback survey was administered to the technicians at
LifeCell. The survey includes questions on -ease of use-learning
curve -comfort -functionality-dermal damage The feedback from
LifeCell was used to validate the final design against the project
metrics. Concept A (see Figure 2) was selected based on discussions
with LifeCell. This device incorporates a bumper system that will
protect the dermal layer, an electrical component that reduces
worker fatigue, longitudinal motion that will reduce worker injury,
a blade replacement mechanism, and a trigger to activate the
device. The stainless steel blades have a serrated cutting edge and
are held in place by a 3-pin system. The blades are removable by
unscrewing the stainless steel bumper. See Figure 6 for a model of
the final design. Path Forward After hand-off of the final
prototype to the sponsor, the path forward will be to produce an
autoclavable replica for evaluation and eventual commercial use by
technicians in the class 100 cleanrooms at LifeCell. BMEG450:
Senior Design, Fall 2013 Figure 2: Concepts A, B, and C Figure 1:
Scalpel blade and handle Figure 3: Pork Belly test Figure 4: Blade
with pin system Figure 5: Visit to LifeCell Table 1: Metrics for
the fat removal tool Metrics were developed in consultation with
LifeCell to address the project constraints (see Table 1). Figure
6. Final design A B C