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S138 Abstracts / Gait & Posture 39S (2014) S1–S141 Fig. 2. BTS Smart movement imaging using the Davis modified model. The kinematic parameters were registered with BTS Smart movement analysis system (Fig. 2). The registration of five mus- cle groups electrical activity in left and right lower limb (m.vastus medialis oblique, m.rectus femoris, plantar flexor group, ham- strings, lateral dorsal flexor group) was carried out with telemetric EMG measurement system NORAXON TeleMyo 2400 G2. Results: 180 movement cycles were registered for each training device. Discussion and conclusions: The measurements results sug- gest there is a statistically significant difference between muscle activation (EMG), range of motion and joint angles in the movement cycles performed on two tested training devices. The registered muscle activation patterns give the opportunity to be compared with muscle activation patterns in the same muscle groups during skiing reported in literature [2]. Reference [1] Bober T, Rutkowska-Kucharska A, Pietraszewski B. Cwiczenia plyometryczne – charakterystyka biomechaniczna, wskazniki zastosowania. Sport wyczynowy 2007;7–9:511–3. [2] Panizzolo FA, et al. Comparative analysis of muscle activation patterns between skiing on slopes and on training devices. Proc Eng 2010;2:2537–42. http://dx.doi.org/10.1016/j.gaitpost.2014.04.197 P82 A longitudinal study of gait function in people with Alzheimer disease Ylva Cedervall 1,, Kjartan Halvorsen 2 , Anna Cristina Åberg 1 1 Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Sweden 2 Department of Information Technology, Uppsala University, Sweden Introduction and aim: Executive and attention dysfunctions have been suggested to be the main cause of early gait impairments and falls in people with Alzheimer’s disease (AD). Walking in daily life, places high demands on the interplay between cognitive and motor functions. A well-functioning ability to dual-tasking is thus essential for walking safely. Identifying changes in gait function during dual-tasking may guide the design of interventions aimed at fall prevention, and contribute to maintaining physical function and among people with AD. The aims were, to study longitudinal changes in gait parameters during single- and dual-task conditions over a period of two years among people with initially mild AD. Patients/materials and methods: Twenty-one individuals with mild AD (Mini Mental State Examination: 21–30), 10 male/11 female: 55–78 years, were included. The data collection was con- Fig. 1. The cross-sectional differences between gait speed at single – task names and dual-task animals. Fig. 2. The dual task cost percent for naming animals. The horizontal line indicates a reference value (9%) for healthy older adults. ducted on three occasions, 12 months apart. A Qualisys ® motion capture system, a three-dimensional optical gait analysis system, was used. Reflecting markers were applied on anatomical land- marks according to a standardized procedure. The participant walked barefoot a distance of 7 m. A six camera Pro Reflex ® sys- tem recorded the position of the markers at a sampling frequency of 240 Hz. At each gait occasion, the following gait parameters were computed: gait speed, step width, -length, -height, and double support time. All gait parameters were examined at the partici- pant’s comfortable gait speed during three different conditions; five single-task trials, three dual-task trials naming names, and three dual-task trials naming animals. The mean values of 3–4 steps in the middle part of each trial were analysed. Results: There was a significant decline in gait speed and step length during single- and dual-tasking. In contrast, no significant longitudinal change could be found in dual-task cost (single-task value–dual-task value). However, the cross-sectional differences between single- and dual-tasks gait parameters were significant for 9/10 comparisons at baseline, 8/10 at the one-year follow-up, and 9/10 at the two-year follow-up. The significant differences for all gait parameters were observed between the one- and the two-year follow-ups. Systematic visual examination of the motion capture files revealed that the gait speed slowing in dual-tasking included, e.g. general hesitating, intermittent stops in single- and double stance (Figs. 1 and 2). Discussion and conclusions: Gait function was found to be markedly affected in early years of AD. In addition to a slowed gait speed, an evident impact of dual-tasking was shown. How- ever, the dual-task cost appeared to remain stable over time. This was unexpected and could be hypothesized to reflect a diminish- ing ability to adjust walking to declining cognitive function. Various gait pattern disturbances were observed during dual-tasking and contributed to the slowed gait speed, and may also increase fall risk. Future research may be focused on identification of people at risk of AD by the use of dual-task methods, and on dual-task walking performances to identify fall risk in AD. http://dx.doi.org/10.1016/j.gaitpost.2014.04.198

A longitudinal study of gait function in people with Alzheimer disease

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S138 Abstracts / Gait & Posture 39S (2014) S1–S141

Fig. 2. BTS Smart movement imaging using the Davis modified model.

The kinematic parameters were registered with BTS Smartmovement analysis system (Fig. 2). The registration of five mus-cle groups electrical activity in left and right lower limb (m.vastusmedialis oblique, m.rectus femoris, plantar flexor group, ham-strings, lateral dorsal flexor group) was carried out with telemetricEMG measurement system NORAXON TeleMyo 2400 G2.

Results: 180 movement cycles were registered for each trainingdevice.

Discussion and conclusions: The measurements results sug-gest there is a statistically significant difference between muscleactivation (EMG), range of motion and joint angles in the movementcycles performed on two tested training devices. The registeredmuscle activation patterns give the opportunity to be comparedwith muscle activation patterns in the same muscle groups duringskiing reported in literature [2].

Reference

[1] Bober T, Rutkowska-Kucharska A, Pietraszewski B. Cwiczenia plyometryczne– charakterystyka biomechaniczna, wskazniki zastosowania. Sport wyczynowy2007;7–9:511–3.

[2] Panizzolo FA, et al. Comparative analysis of muscle activation patterns betweenskiing on slopes and on training devices. Proc Eng 2010;2:2537–42.

http://dx.doi.org/10.1016/j.gaitpost.2014.04.197

P82

A longitudinal study of gait function in peoplewith Alzheimer disease

Ylva Cedervall 1,∗, Kjartan Halvorsen 2, AnnaCristina Åberg 1

1 Department of Public Health and CaringSciences/Geriatrics, Uppsala University, Sweden2 Department of Information Technology, UppsalaUniversity, Sweden

Introduction and aim: Executive and attention dysfunctionshave been suggested to be the main cause of early gait impairmentsand falls in people with Alzheimer’s disease (AD). Walking in dailylife, places high demands on the interplay between cognitive andmotor functions. A well-functioning ability to dual-tasking is thusessential for walking safely. Identifying changes in gait functionduring dual-tasking may guide the design of interventions aimedat fall prevention, and contribute to maintaining physical functionand among people with AD. The aims were, to study longitudinalchanges in gait parameters during single- and dual-task conditionsover a period of two years among people with initially mild AD.

Patients/materials and methods: Twenty-one individuals withmild AD (Mini Mental State Examination: 21–30), 10 male/11female: 55–78 years, were included. The data collection was con-

Fig. 1. The cross-sectional differences between gait speed at single – task namesand dual-task animals.

Fig. 2. The dual task cost percent for naming animals. The horizontal line indicatesa reference value (9%) for healthy older adults.

ducted on three occasions, 12 months apart. A Qualisys® motioncapture system, a three-dimensional optical gait analysis system,was used. Reflecting markers were applied on anatomical land-marks according to a standardized procedure. The participantwalked barefoot a distance of 7 m. A six camera Pro Reflex® sys-tem recorded the position of the markers at a sampling frequencyof 240 Hz. At each gait occasion, the following gait parameters werecomputed: gait speed, step width, -length, -height, and doublesupport time. All gait parameters were examined at the partici-pant’s comfortable gait speed during three different conditions; fivesingle-task trials, three dual-task trials naming names, and threedual-task trials naming animals. The mean values of 3–4 steps inthe middle part of each trial were analysed.

Results: There was a significant decline in gait speed and steplength during single- and dual-tasking. In contrast, no significantlongitudinal change could be found in dual-task cost (single-taskvalue–dual-task value). However, the cross-sectional differencesbetween single- and dual-tasks gait parameters were significantfor 9/10 comparisons at baseline, 8/10 at the one-year follow-up,and 9/10 at the two-year follow-up. The significant differencesfor all gait parameters were observed between the one- and thetwo-year follow-ups. Systematic visual examination of the motioncapture files revealed that the gait speed slowing in dual-taskingincluded, e.g. general hesitating, intermittent stops in single- anddouble stance (Figs. 1 and 2).

Discussion and conclusions: Gait function was found to bemarkedly affected in early years of AD. In addition to a slowedgait speed, an evident impact of dual-tasking was shown. How-ever, the dual-task cost appeared to remain stable over time. Thiswas unexpected and could be hypothesized to reflect a diminish-ing ability to adjust walking to declining cognitive function. Variousgait pattern disturbances were observed during dual-tasking andcontributed to the slowed gait speed, and may also increase fall risk.Future research may be focused on identification of people at riskof AD by the use of dual-task methods, and on dual-task walkingperformances to identify fall risk in AD.

http://dx.doi.org/10.1016/j.gaitpost.2014.04.198