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A. D. Katsambas· T. M. Lotti (Eds.)
European Handbook of Dermatological Treatments
Springer-Verlag Berlin Heidelberg GmbH
A. D. Katsambas T. M. Lotti (Eds.)
European Handbook of Dermatological Treatments
2nd, revised reprint
, Springer
Professor Andreas D. Katsambas University of Athens - Greece of Dermatology and Venerology 35, Skoufa Str. GR-106 73 Athens Greece
Professor Torello M. Lotti University of Florence, Florence, Italy 23, Via Dante Alghierie I-51015 Montecatini Terme (PT) Italy
2"d revised reprint 2000
The Library of Concress has cataloged the original printing as follows:. European handbook of dermatological treatments/ A.D. Katsamaba, T.M. Lotti, eds.
p. cm. Includes bibliographical references. ISBN 978-3-662-03837-6 ISBN 978-3-662-03835-2 (eBook) DOI 10.1007/978-3-662-03835-2 1. Skin--Deseases--Handbooks, manuals, etc. 2. Dermatology
·Handbooks, manuals, etc.!. Katsambas, A.D. (Andreas D.), 1944· 1!. Lotti, T. M. (Torello M.), 1953- . [DNLM: 1. Skin Diseases--therapy. 2. Skin Diseases--diagnosis.
3. Diagnosis, Differential. 4· Dermatologie Agents--administration & dosage. WR 650 E89 1999) RL74.E94 1999 616.5--dc21 DNLM/DLC for Library of Congress
This work is subject to copyright. Ali rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in ohter way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright. Law of September 9,1965, in its current version, and permission for use must always be obtained from Springer-Verlag Berlin Heidelberg GmbH. Violations are liable prosecution under the German copyright law.
© Springer-Verlag Berlin Heidelberg 2000
Originally published by Springer-Verlag Berlin Heidelberg New York in 2000 Softcover reprint of the hardcover 2nd edition 2000
The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
Produci Liability: The publisher cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature.
Cover design: E. Kirchner, Heidelberg
Typesetting: cicero Lasersatz, Dinkelscherben
Printed on acid-free paper- SPIN: 10773671- 22/3130 - 5 4 3 2
Preface
This handbook presents the combined work of many prominent dermatologists from throughout Europe, based on their profound knowledge and clinical experience in various fields of dermatology.
The purpose of this manual is to provide an easy to use guide that describes not only the many dermatological diseases diagnosed today, but also the analogous drugs and methods of treatment available. Hence, as indicated in the title, dermatologists and non-dermatologists will find its contents to be most useful and concise.
The manual is divided into three main sections, diseases, methods, and drugs. The first part of the Handbook defines each disease with brief information on its etiology and pathophysiology. This is followed by a short account of diagnostic procedures and an extensive discussion of treatment and therapy. The authors try not only to present the classic and modern approaches to treatment, but also to provide their personal recommendations on the base of their expertise. The middle section describes up-todate methods and the possible use of therapeutic equipment, for diagnosis and treatment. The final part provides an alternative approach, indicating where medication and drugs could be an appropriate choice in the treatment of dermatological diseases.
This is simply a corrected edition of the European Handbook of Dermatological Treatments, which has been minimally revised and retains the exact form of the previous publication.
The response received from the initial publication of the Handbook, was enthusiastic and the book was widely accepted. It has been a great pleasure to provide this Handbook to fellow colleagues and new dermatologists in the continuing endeavour to treat dermatological and cutaneous diseases.
We wish to express our gratitude to all the distinguished colleagues who contributed towards this venture.
Andreas Katsambas Torello Lotti
Contents
Diseases
Acne .............. . W.J. Cunliffe, and D.C. Seukeran
Acne Inversa ................ . R. Chatelain, C. Hary, B. Konz, and G. Plewig
Actinic Keratosis ... F. Camacho-Martinez
Adamantiades-Beh~et's Disease C.C. Zouboulis
Alopecia Areata Management R.Happle
Androgenic Alopecia . . . . . . . . . . . . C. Pierard-Franchimont, and G.E. Pierard
Antiphospholipid Syndrome ...... . P.G. Vlachoyiannopoulos, and H.M. Moutsopoulos
Aphthous Stomatitis G.Laskaris
Apocrine Miliaria . . . . . . . . H.R. Bruckbauer, and H.J. Vogt
Atopic Dermatitis . . . . . . . E.J.M. Van Leent, and J.D. Bos
Balanitis .. D.Freedman
Basal Cell Carcinoma D. Roseeuw, and A.D. Katsambas
3
11
15
21
31
38
44
51
56
58
69
75
VIII
Bowen's Disease G. Avgerinou
Bullous Pemphigoid A. Varelzidis
Candidiasis (Candidosis-Moniliasis-Trush) D. Rigopoulos
Contents
89
92
99
Chronic Actinic Dermatitis .............................. 106 G.M.Murphy
Cicatricial Alopecia . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 111 A. Tosti, and B.M. Piraccini
Contact Dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 117 L.Kanerva
Cutaneous Vasculitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 127 T.Ryan
Darier's Disease. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 131 C. Varotti, and F. Bardazzi
Dermatitis Herpetiformis . . . . . . . . . . . . . . . . . . . . . . . . . . .. 134 C. Gooptu, and F. Wojnarowska
Dermatomyositis S. Jablonska
............................ 138
Dermatophyte Infections .............................. 144 A. Tosti, and B.M. Piraccini
Diaper Dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 149 S. Reimann, and T.A. Luger
Drug-Induced Pemphigus. ............................. 153 K.E. Harman, and M.M. Black
Drug Eruption J.Revuz
............................. 155
Drug Photosensitivity ................................. 159 P. Santoianni, and E.M. Procaccini
Eccrine Miliaria . . . . . . . . . .... . . . . . . . . . . . . . . . . . . . . .. 164 H.R. Bruckbauer, and H.J. Vogt
Contents IX
Epidermolysis Bullosa ........ . 167 G. Menchini, B. Bianchi, and T. M. Lotti
Erysipelas .. . M. Balabanova
. ....................... 177
Erythema Multiforme ................................. 181 F. M. Brandao
Erythema Nodosum .................................. 185 A.Claudy
Erythrasma ....................................... 189 E. Koumantaki-Mathioudaki
Erythroplasia of Queyrat ............................... 192 B.-R.Balda
Factitial Dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 195 N. Tsankov, and 1. Stranski
Folliculitis . . G.R. Rousselet
.............................. 198
Furuncles and Carbuncles ..................... 202 R. Stadler, and M. Westenberger-Treumann
Gonorrhoea M.A. Waugh
Granuloma Annulare N. Raison-Peyron, and J. Meynadier
Hand Dermatitis ... K. Thestrup-Pedersen
..................... 209
......................... 212
. ........................ 218
Herpes Simplex Genitalis . . . . . . . . . . . . . . . . . . . . . . . . . . 224 P. Teofoli, P. Puddu, and T. M. Lotti
Herpes Simplex Virus Infection (Oro-facial) . . . . . . . . . . . . . . . . . . . . . 229 S.Kroon
Herpes Zoster . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234 S. Georgala
Hirsutism ....................................... 241 S. Rogers
x Contents
HIV Infection and AIDS: Present Status of Antiretroviral Therapy R. Husak, L. U. WOlfer, and C.C.E. Orfanos
.. 246
Hyperhidrosis . . . . . . . . . . . . . . .. ..................... 256 G. Campanile, G. Hautmann, and T.M. Lotti
Ichthyoses . . . . . . . . . . . M. Paradisi, and A. Giannetti
. .................... 261
Impetigo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 S. Veraldi, and R. Caputo
Kaposi's Sarcoma J.D. Stratigos
................................ 272
Keloids and Hypertrophic Scars . . . . . . . . . . . . . . . . . . . . . . . . . 281 G. Hautmann, and A. Mastrolorenzo
Keratoacanthoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287 P. Campolmi, M. Benci, C. Vallecchi, and T. M. Lotti
Leg Ulcers .. A.A. Ramelet
. ................ 292
Leishmaniasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301 M. Onder, and M.A. Gurer
Lentigo Maligna .................................... 308 R.P.R. Dawber, and Z.S. Gaspar
Leprosy or Hansen's Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 B. Flageul, and L. Dubertret
Lichen Planus A.Rebora
.............................. 324
Lichen Simplex Chronicus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328 M. Gantcheva
Lupus Erythematosus ................................ 333 B. Crickx, and S. Belaich
Lymphomas Primary Cutaneous ........................... 340 W.A. van Vloten
Malignant Melanoma ................................. 355 B.R.Balda
Contents
Mastocytosis (Urticaria Pigmentosa) A.P. Oranje, and D. Van Gysel
XI
363
Melasma . . . . . . . . . . .. ............................ 368 A.D. Katsambas, and T.M. Lotti
Mite Bites G.Leigheb
............................ 374
Molluscum Contagiosum ............................... 376 M. V. Milinkovic, and L. M. Medenica
Morphea: Circumscribed Scleroderma . . . . . . . . . . . . . . . . . . . . . . . . 384 U. F. Haustein
Necrobiosis Lipoidica ................................. 387 E. Grosshans
Nevi (Benign Melanocytic) .............................. 392 N. G. Stavrianeas
Nummular Eczema ................................... 407 H.R. Bruckbauer, S. Karl, and J. Ring
Pediculosis G. Campanile, and G. Hautmann
Pemphigus Erythematosus K.E. Harman, and M.M. Black
......................... 414
........................... 419
Pemphigus Foliaceus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421 K.E. Harman, and M.M. Black
Pemphigus Vegetans .................................. 425 K.E. Harman, and M.M. Black
Pemphigus Vulgaris ............................. 428 V. Ruocco, and S. Brenner
Photo ageing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437 N.M. Craven, and C.E.M. Griffiths
Pityriasis Lichenoides Acuta . . . . . . . . . . . . . . . . . . . . . . . . . . . 441 L. Andreassi
Pityriasis Lichenoides Chronica . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445 G. Lange Vejlsgaard
XII
Pityriasis Rosea H.Degreef
Contents
.. 449
Pityriasis Rubra Pilaris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453 W.A.D. Griffiths
Polymorphic Light Eruption (PLE) . . . . . . . . . . . . . . . . . . . . . . . . . . 459 J. Ferguson, and A.D. Katsambas
Porphyrias ...... . . .......................... 463 M. Lecha, and C. Herrero
Pruritus .. D. Ioannides
. ............................... 470
Psoriasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477 U. Mrowietz, and E. Christophers
Purpuras ............. . . . . . . . . . . . . . . . . . . . . . . 488 T.M. Lotti, C. Comacchi, and 1. Ghersetich
Pyoderma Gangrenosum M. Camilleri, and J.1. Pace
...................... 494
Raynaud's Phenomenon ............................... 504 C.G.M. Kallenberg
Rosacea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508 F.C.Powell
Sarcoidosis ....................................... 515 A.Rebora
Scabies .. . ................................ 518 A. G6rkiewicz-Petkow
Seborrheic Dermatitis ................................. 523 J. Faergemann
Seborrheic Keratosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527 A. Picoto
Sjogren's Syndrome .................................. 531 A.G. Tzioufas, and H.M. Moutsopoulos
Skin Diseases from the Marine Environment .................... 536 G. Monfrecola
Contents
Solar Urticaria M. Jeanmougin
XIII
541
Squamous Cell Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . 545 D. Roseeuw, and A. D. Katsambas
Subacute Cutaneous Lupus Erythematosus ..................... 549 M.N. Manoussakis, and H.M. Moutsopoulos
Syphilis .. M.A. Waugh
. .................... 556
Systemic Sclerosis - Scleroderma . . . . . . . . . . . . . . . . . . . . . . . . . . . 564 U. F. Haustein
Tick Dermatoses .................................... 570 G.Leigheb
Tinea Versicolor. Pityriasis Versicolor . . . . . . . . . . . . . . . . . . . . . . . . . 572 M. Le Maitre, and A. Dompmartin
Toxic Epidermal Necrolysis A.Minas
.......................... 577
Urethritis: Gonococcal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583 D. Freedman
Urethritis: Nongonococcal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 D. Freedman
Urticaria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595 F. Lawlor, and M.W. Greaves
Varicella .. S. Georgala
. ............................. 602
Vascular Birthmarks: Vascular Malformations and Haemangiomas . . . . . . . . 608 H. Yang, and G. W. Cherry
Vitiligo ......................................... 617 A.D. Katsambas, T.M. Lotti, and J. P. Ortonne
Warts and Condylomas ..... . .................... 624 J.M. Mascaro, and J.M. Mascaro Jr.
Xanthomas .......... . . ......................... 631 A.D. Tosca, and J.C. Katsantonis
XIV Contents
Methods
Biopsy .......................................... 639 E.Haneke
Chemical Peelings ................................... 645 1. Ghersetich, P. Teofoli, M. Ribuffo, and T.M. Lotti
Cryosurgery . . . . . . . . . M.C. Boullie, and Ph. Lauret
Curettage E.Haneke
. ................. 657
.............................. 662
Electrosurgery ..................................... 664 E.Haneke
Epiluminescence Microscopy of Pigmented Skin Lesions . . . . . . . . . . . . . . 668 V. De Giorgi, and P. Carli
Extracorporeal Photo chemotherapy ......................... 675 B.R.Balda
Hair Restoration Surgery ............................... 678 S. Letessier
Lasers in Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687 1. Leite
Moh's Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693 A. Picoto, J.M. Labareda, R. Themido, and F. Coelho
Patch Testing A.Katsarou
................. 696
Photo chemotherapy .................................. 702 Ch. Antoniou
Sclerotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 707 E. Del Bianco, G. Muscarella, and P. Cappugi
Skin Augmentation (Fillings) 1. Rusciani, and S. Petraglia
..................... 712
Skin Resurfacing with the CO2 Laser ......................... 720 S. Letessier, and C. Veres
UVB Phototherapy Ch. Antoniou
................................ 727
Vaccine Strategies via Dendritic Cells in the Treatment of Malignant Melanoma 730 S. Moretti, and T.M. Lotti
Contents xv
Drugs
Antibacterial Agents in Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . 737 H. Giamarellou
Antifungals .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 748 V. Bettoli, and A. Tosti
Antihistamines ..................................... 756 A.D. Katsambas,A. Stratigos, and T.M. Lotti
Antiviral Drugs ..................................... 762 G. Hautmann, G. Campanile, E. Puma, and A.D. Katsambas
Bleaching Agents . . . . . . . W. Westerhof, and M.D. Njoo
. ........... 766
Corticosteroids Topical . . . . . . . . . . . . . . . . . . . . . . . . 778 J.G. Camarasa, and A. Gimenez-Arnau
Glucocorticoids Systemic ............................... 787 J.G. Camarasa, and A. Gimenez-Arnau
Insect Repellents ... S. Motta, and M. Monti
. ....................... 797
Psychoactive Agents in Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . 803 G. Hautmann, and E. Panconesi
Retinoids J.H. Saurat
............................ 812
Scabicides and Pediculicides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 A. G6rkiewicz-Petkow
Sunscreens ....................................... 825 D. Rigopoulos, Ch. Antoniou, and A.D. Katsambas
Topical Anaesthetics in Dermatology . . . . . . . . . . . . . . . . . . . . . . 829 F. B. de Waard-van der Spek, and A.P. Oranje
Topical Preparation and Vehicles M. Monti, and S. Motta
..................... 834
Subject Index .... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847
List of contributors
Andreassi, L. Dept. of Dermatology, Policlinico "Le Scotte", University of Siena, Siena-Italy
Antoniou, Ch. "A Sygros Hospital", 5 Dragoumi St., Athens 16121-Greece
Avgerinou, G. Dept. of Dermatology, University of Athens, "A Sygros Hospital", 5 Dragoumi St., Athens 16121-Greece
Balabanova, M. Dept. of Dermatology, Medical University, Sofia-Bulgaria
Balda,B.R. Dept. of Dermatology & Allergology, Zentralklinikum Augsburg, Stenglin StraBe 2, D-86156 Augsburg-Germany
Bardazzi, F. Dept. of Dermatology, Faculty of Medicine, University of Bologna, V. Massarenti 1, 1-40138 Bologna-Italy
Belaich,S. 101, Rue de Rennes, F-75006 Paris-France
Bettoli, V. Universita degli Studi di Bologna, Dept. di Medicina Clinica Specialistica e Sperimentale, Clinica Dermatologica, Ospedale Policlinico S. Orsola-Malpighi, Via Massarenti, 1-40138 Bologna-Italy
Bianchi,B. Via Crispi 38, Pisa 56100-Italy
Black,M.M. st. John's Institute of Dermatology, st. Thomas's Hospital, Lambeth Palace Road, London SE17EH-England
Bos,J.D. Dept. of Dermatology AO 252, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE-Amsterdam-The Netherlands
XVIII List of contributors
Boullie, M. C. Hopital Charles Nicolle, 1, Rue de Germont, Rouen-France
Brandao,F. R. S. Domingos, A Lapa 89-5, P-1200 Lisboa-Portugal
Brenner, S. Dept. of Dermatology, Sourasky Medical Center, Tel Aviv-Israel
Bruckbauer, H. R. Dept. of Dermatology & Allergy, am Biederstein, Technical University Munich, BiedersteinerstraBe 29, D-80802 Munich-Germany
Camacho-Martinez, F. Universitdad de Sevilla, Dept. de Dermatologia, Avda. Republica, Argentina 22,5 D, Sevilla-Spain
Camarasa, J. Dermatology Department, Hospital del Mar. 1M 1M, Univ. Autonoma de Barcelona, Passceig Maritim 25-29,08003 Barcelona-Spain
Camillier, M. Mayo-Clinic, Minnesota -USA
Campanile, G. L. Dept. of Dermatology, University of Florence, 37 via Alfani, 1-50121 Florence-Italy
Campolmi, P. Dept. of Dermatology, University of Florence, Florence-Italy
Caputo,R. Institute of Dermatologic Science, University of Milan, Milan -Italy
Cappugi,P. Dept. of Dermatology, University of Florence, Florence-Italy
Carli, P. Dept. of Dermatology, University of Florence, 37 via Alfani, 1-50121 Florence-Italy
Chatelain, R. Dermatologische Klinik & Poliklinik, Ludwig-Maximilians, Univ. Mtinchen, FrauenlobstraBe 9-11, D-80337 Munich-Germany
Cherry,G. Churchill Hospital, Headington, Oxford OX3 7LJ-UK
Christophers, E. Dept. of Dermatology, University of Kiel, SchittenhelmstraBe 7, D-24105 Kiel-Germany
List of contributors
Claudy,A. Clinique Dermatologique, Hopital Edouard Herrior, Place d' Arsanval, F-69437 Lyon Cedex 03-France
Coelho,F. Superior Technician Farmacy, Centro de Dermatologia Medic-Cirurgica, ARS de Lisboa e Vale do Tejo, Rua Jose Estevao 135,1150 Lisboa-Portugal
Comacchi, C. Dept. of Dermatology, University of Florence, 37 via Alfani, U -50121 Florence-Italy
Craven, N. M. Section of Dermatology, University of Manchester, Manchester-UK
Crickx,B. Paris-France
Cunliffe, W. J. Skin Research Centre, The General Infirmary at Leeds-Leeds LSI3EX-UK
Dawber, R. P. R. Dept. of Dermatology, The Churchill Hospital, OX3 7LJ Oxford-UK
Del Bianco, E. Dept. of Dermatology, Univ. of Florence, Florence-Italy
De Giorgi Dept. of Dermatology, University of Florence, 37 via Alfani, I -50121 Florence-Italy
Degreef,H. Universitaire Ziekenhuizen Leuven Derm., UZ Sint-Rafael, Kapucijnenvoer 35, B-3000 Leuven-Belgium
De Waard-Van der Spek, F. B.
XIX
Dept. of Dermato-Venereology, Univ. Hospital Rotterdam, Rotterdam-The Netherlands
Dompmartin, A. Caen-France
Dubertret, L. Dept. of Dermatology, Hospital Henri Mondor, 51 Av. Du Marechal Lattre de Tassigny, F-94010 Creteil-France
Faergemann, J. Dept. of Dermatology, Sahlgrenska University Hospital, S-41345 Gothenburg-Sweden
Ferguson, J. Photobiology Unit, Ninewells Hospital and Medical School, Dundee, DDI 9SY-Scotland
xx
Flageul, B. Paris-France
Figueiredo, A. Rua Infanta D. Maria Lt 38-B 3 Esq, P-303 Coimbra-Portugal
Freedman, D. 88 Ranelagh Village, Dublin 6-Ireland
Gantcheva, M.
List of contributors
Dept. of Dermatology, Medical University, 1 Georgi Sifiiski Str., 1431 Sofia-Bulgaria
Gaspar, Z. S. Princess Alexandra Hospital, Woollongabba, Queensland-Australia
Georgala, S. Dept. of Dermatology, University of Athens, "A Sygros Hospital", Athens-Greece
Ghersetich, I. Dept. of Dermatology, University of Florence, via degli Alfani 37, 1-50121 Florence-Italy
Giamarellou, H. Athens University School of Medicine, Infectious Diseases Department, "Laiko General Hospital", Athens 11527-Greece
Gimenez-Arnau, A. Dept. of Dermatology, Hospital del Mar. 1M 1M, Univ. Autonoma de Barcelona, Passeig Maritim 25-29, 08003 Barcelona-Spain
Giannetti, A. Dept. of Dermatology, University of Modena, via del Pozzo 71,1-41100 Modena-Italy
Gooptu,c. Dept. of Dermatology, The Churchill Hospital, Headington OS3 7LJ Oxford-UK
Gorkiewicz-Petkow, A. Dept. of Dermatology, Warsaw School of Medicine, Koszykowa 82A, 02-008 Warsaw-Poland
Greaves,M. St. John's Institute of Dermatology, St. Thomas's Hospital, Lambeth Palace Road, London SE17EH-UK
Griffiths, C. E. M. Section of Dermatology, Univ. Manchester School of Medicine, Hope Hospital, Manchester M6 8HD-UK
List of contributors
Griffiths, W. A. D. st. John's Institute of Dermatology, st. Thomas's Hospital, Lambeth Palace Road, London SE17EH-UK
Grosshans, E. Clinique Dermatologique, Faculte de Medicine, I-Place de l'Hopital, F-67091 Strasbourg-France
Gurer Ali, M. GAZI University, Ankara -Turkey
Haneke,E. Hautklinik, Arrenbergerstra6e 20-56, D-42117 Wuppertal-Germany
Happle,R. Dept. of Dermatology, Philipp Univ. of Marburg, Deutschhausstra6e 9, D-35033 Marburg-Germany
Harman, K. E. st. John's Institute of Dermatology, St. Thomas's Hospital, Lambeth Palace Road, London SE17EH-UK
Hary,C. Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Univ. Munich, Frauenlobstra6e 9-11, D-80337 Munich-Germany
Haustein, u.F. Dept. of Dermatology, Univ. of Leipzig, Liebigstra6e 21, D-04103 Leipzig-Germany
Hautmann, G. Dept. of Dermatology, Univ. of Florence, 37 via Alfani, 1-50121 Florence-Italy
Herrero,C. Servei de Dermatologia, Hospital Clinic, Facultat de Medicina, Univ. de Barcelona, Barcelona-Spain
Husak,R. Dept. of Dermatology, Univ. Medical Ctr BF, The Free University of Berlin, Hindenburgdamm 30, D-12200 Berlin-Germany
loannides, D. Dept. of Dermatology, Aristotle Univ., Medical School, 3 PP Germanou Street, 54622 Salonika-Greece
Jablonska, S. Dept. of Dermatology, Warsaw School of Medicine, Koszykowa 82a, 02-008 Warsaw-Poland
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Jeanmougin, M. 155 Boulevard Magenta, F-75009 Paris-France
Kallenberg, C. G. M. Cronningen-The Netherlands
Kanerva,L. Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN -00250 Helsinki -Finnland
Karl, S.
List of contributors
Dept. of Dermatology & Allergy, am Biederstein, Technical University Munich, BiedersteinerstraBe 29, D-80802 Munich-Germany
Katsambas, A. D. Dept. of Dermatology, University of Athens, "A Sygros Hospital", 5 Dragoumi St., Athens 16121-Greece
Katsantonis, J. c. Dept. of Dermatology, Faculty of Medicine, University of Crete, Heraklion 71110 Crete-Greece
Katsarou, A. Dept. of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi Street, Athens 16121-Greece
Konz,B. Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Univ. Munich, FrauenlobstraBe 9-11, D-80337 Munich-Germany
Koumantaki-Mathioudaki, E. Dept. of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi Street, Athens 16121-Greece
Kroon,S. Pederstupvej 40, DK-5210 Odens NV-Denmark
Labareda, J. M. Centro de Dermatologia Medico-Cirurgica, ARS de Lisboa e Vale do Tejo, Rua Jose Estevao 135,1150 Lisboa-Portugal
Vejlsgaard-Lange, G. Rigshospitalet Copenhagen Univ. Hospital, The Rhima Center, Tagensvej 20, DK-22o Copenhagen N-Denmark
Larregue, M. 350, Avenue Jacques-Coeur, 86021 Poitiers, France
List of contributors XXIII
Laskaris, G. Dept. of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi Street, Athens 16121-Greece
Lauret, Ph. Hopital Charles Nicolle, 1, rue de Germont, Rouen-France
Lawlor, F. Dermatology Unit, St. Andrew's Hospital, Devas Street, Bow London E3 3NT -UK
Lecha,M. Servei de Dermatologia, Hospital Clinic, Facultat de Medicina, Univ. de Barcelona, c/VillarroeI170, E-08036 Barcelona-Spain
Ledo,A. Pasei de la Castellana 167, E-28046 Madrid-Spain
Leigheb,G. Dept. di Science Mediche, Universita degli studi di Torino, via Solaroloi 17, 1-28100 Novara-Italy
Leite, L. Calcada da Ajuda 82-1, P-1300 Lisboa -Portugal
Le Maitre, M. 1 Avenue de 6 Juin, F-14000 Caen-France
Letessier, S. 28 Place Saint-Ferdinand, F-75017 Paris-France
Lotti, T.M. Dept. of Dermatology, University of Florence, 37 via Alfani, 1-50121 Florence-Italy
Luger, T.A. Universitats-Hautklinik Munster, Von-EsmarchstraBe 56, D-48149 Munster-Germany
Manoussakis, M. N. Dept. of Pathophysiology, School of Medicine, University of Athens, Greece
Mascaro, J. M. Hospitale Clinic, Dept. of Dermatology, Casanova 143, E-08036 Barcelona-Spain
Mascaro, J. M. Jr. Hospitale Clinic, Dept. of Dermatology, Casanova 143, E-08036 Barcelona-Spain
Mastrolorenzo, A. Dept. of Dermatology, University of Florence-Italy
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Medenica, 1. J. M. Belgrade-Yugoslavia
Menchini, G. Dept. of Dermatology, University of Siena, Siena-Italy
Meynadier, J.
List of contributors
Service de Dermatologie, Hopital st. Eloi, 2 Avenue Bertin Sans, F-34295 Montpellier Cedex 5-France
Millinkovic, M. M. Dept. of Dermatology, University of Belgrade, Belgrade-Yugoslavia
Minas,A. Dept. of Dermatology, Aristotle University Medical School,3 PP Germanou St, 54622 Salonica-Greece
Monfrecola, G. Dept. of Dermatology, University Frederico II of Naples, Via Pansini 5, 1-80131 Napoli-Italy
Monti,M. University of Milan, Istituto Clinico Humanitas, Unit of Dermatology, Via Manzani 56, 1-20089 Rozzana Milano-Italy
Moretti, S. Dept. of Dermatology, University of Florence, Florence-Italy
Motta,S. University of Milan, Istituto Clinico Humanitas, Unit of Dermatology, Via Manzani 56, 1-20089 Rozzana Milano-Italy
Muscarella, G. Dept. of Dermatology, Univ. of Florence, Florence-Italy
Moutsopoulos, H. M. Dept. of Pathophysiology, School of Medicine, National University of Athens, Greece
Mrowietz, U. Dept. of Dermatology, University of Kiel, SchittenhelmstraBe 7, D-24105 Kiel-Germany
Murphy, G. M. National Photobiology Unit, Beaumont Hospital, Dublin-Ireland
Njoo,M.D. Netherlands Institute for Pigmentary, Disorders, AMC IWO Gebouw, Meibergdreef 35, 1105 AZ Amsterdam-The Netherlands
List of contributors
Onder,M. Dept. of Dermatology, GAZI University, Ankara-Turkey
Oranje, A. P. Dept. of Dermato-Venereology, University Hospital & Erasmus Univ., Rotterdam-The Netherlands
Orfanos, C.E. Dept. of Dermatology, Univ. Medical Center BF, The Free Univ. of Berlin, Berlin-Germany
Ortonne, J.-P. Service de Dermatologie, Hopital de l' Archet II, Nice-France
Pace, J. L. University of Malta School, Msida & st. Philip's Hospital, Venera-Malta
Panconesi, E. Dept. of Dermatology, University of Florence, Florence-Italy
Paradisi, M. lstituto San Gallicano, Rome-Itlay
Petraglia, S. Catholic University, Dept. of Dermatology, Lgo A. Gemelli 8, 00168 Rome-Italy
Picoto,A. Centro de Dermatologia, Medico-Cirurgica de Lisboa, Lisboa-Portugal
Pierard, G. E.
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Dept. of Dermatopathology, Univ. Of Liege, CHU Sart Tilma, B-4000 Liege-Belgium
Pierard-Franchimont, C. Dept. of Dermatopathology, Univ. Of Liege, CHU Sart Tilma, B-4000 Liege-Belgium
Piraccini, B. M. Dept. of Dermatology, University of Bologna, Bologna-Italy
Plewig,G. Dept. of Dermatology, Ludwig-Maximilians University, Munich-Germany
Powell, F. Regional Centre of Dermatology, Mater Hospital, Dublin-7-lreland
Procaccini, E. M. Dept. of Dermatology, University of Naples, Naples-Italy
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Raison-Peyron, N. Montpellier-France
Ramelet, A. A. 2 Place Benjamin Constant, CH-lO03 Lausanne-Switzerland
Rebora,A. Dept. of Dermatology, University of Genoa, Genoa-Italy
Reimann,S. Dept. of Dermatology, University of Munster, Munster-Germany
Revuz,J.
List of contributors
Service de Dermatologie, Hopital Henri-Mondor, F-94010 Creteil Cedex-France
Ribuffo,M. Dept. of Immundermatology, IDI IRCCS, Rome-Italy
Rigopoulos, D. Univ. Dermatological Clinic, "A Sygros Hospital", 5, I Dragoumi Street, Athens 16121-Greece
Ring,J.O. Dept. of Dermatology & Allergy Biederstein, Technical University Munich, Munich -Germany
Rogers, S. St. Vincent's Hospital, Elm Park, Dublin 4-Ireland
Roseeuw,D. Academic Hospital, Free Univ. of Brussels, Belgium -Brussels
Rousselet, G. R. Choisy Ie Roi -France
Ruocco,V. Dept. of Dermatology, Second Univ. of Naples, Naples-Italy
Rusciani, L. Catholic University, Rome-Italy
Ryan, T. Hill House, Abberbury Avenue, Iffley, OX44EU Oxford-UK
Santoianni, P. Dept. of Dermatology, University of Naples, Naples-Italy
List of contributors XXVII
Saurat, J.-H. Dept. of Dermatology, Geneva-Switzerland
Stadler, R. Hautklinik, Klinikum Minden, PortastraBe 7-9, D-32423 Minden-Germany
Stavrianeas, N. G. Dept. of Dermatology, Univ. of Athens, "A Sygros Hospital", Athens-Greece
Stratigos, A. J. Dept. of Dermatology, Univ. of Athens-Greece
Stratigos, J. D. Dept. of Dermatology, Univ. of Athens-Greece
Teofoli,P. Dept. of Immunodermatology, Instituto Dermopatico, del'Immacolata, Rome-Italy
Themido,R. Centro de Dermatologia Medico-Cirurgica,ARS de Lisboa e Vale do Tejo, Rua Jose Estevao 135,1150 Lisboa-Portugal
Thestrup-Pedersen, K. Dept. of Dermatology, Marselisborg Hospital, Univ. of Aarhus, Aarhus C-Denmark
Tosca,A.D. Dept. of Dermatology, Faculty of Medicine, Univ. of Crete, Heraklion 71110 Crete-Grasse
Tosti,A. Univ. degli Studi di Bologna, Clinica Dermatologica, Osepdale Polic1inico S. Orsola-Malpighi, Via Massarenti 1,1-40138 Bolognia-Italy
Tsankov,N. Medical University, Dept. of Dermatology, 1 Georgi Sofiski Str, 1431 Sofia-Bulgaria
Tzioufas,A. G. Dept. of Pathophysiology, School of Medicine, Univ. of Athens, Athens-Greece
Van Gysel, D. Dept. of Pediatrics, Ons Lieve Vrouw Hospital, Aalst -Belgium
Van Leent, E. J. M. Dept. of Dermatology, Academic Medical Center, Univ. of Amsterdam, PO Box 22700, 1100 DE Amsterdam
Van Vloten, W. Dept. of Dermatology, Univ. Hospital, Utrecht-The Netherlands
XXVIII List of contributors
Varelzidis, A. Dept. of Dermatology, University of Athens, Athens-Greece
Varotti, C. Dept. of Dermatology, University of Bologna, Bologna-Italy
Veraldi, S. Inst. of Dermatological Sciences, University of Milan, Via Pace 9, 20122 Milan-Italy
Veres, C. 5 rue Villebois-Mareuil, 75017 Paris-France
Vlachoyiannopoulos, P. G. Dept. of Pathophysiology, National University of Athens, Athens-Greece
Vogt,H.J. Dept. of Dermatology & Allergy, am Biederstein, Technical University of Munich, BiedersteinerstraBe 29, D-80802 Munich-Germany
Waugh,M.A. University of Leeds, General Infirmary at Leeds-Leeds-KU
Westenberger-Treumann, M. Hautklinik, Klinikum-Minden, PortastraBe 7-9
Westerhof, W. Netherlands Institute for Pigmentory Disorders,Amsterdam-Netheriands
Wolfer, L. U. Dept. of Dermatology, Univ. Medical Center, Free Univ. of Berlin, Hindenburgdamm 30, 12200 Berlin-Germany
Yang,H. Dept. of Dermatology, Oxford-UK
Zouboulis, C. C. Dept. of Dermatology, Univ. Medical Center BF, The Free Univ. of Berlin, Berlin-Germany