A Conical Connection Implant3/4/5mm CW-HA350 CW-HA450 CW-HA550 Ø 5.8mm Standard Platform Screw type implant range Implants cover screw and healing caps. Available in heights: 3,4,5,6mm

®

M A K E I T S I M P L E

A Conical Connection Implant

P.16-17

P.18-19

P.20-21

P.23

P.14-15

P.12-13

P.11

P.10

P.9

P.8

P.6-7

P.4-5

P.22

P.24-25

MIS Warranty:

MIS exercises great care and effort in maintaining the superior quality of its products. All MIS products are guaranteed to be free from defects in material and workmanship. However, should a customer find fault with any MIS product after using it according to the directions, the defective product will be replaced.

Warning: Products should be used by licensed dentists only.

Introduction

Advantages

Implant range

Ø3.75mm Implants

Ø4.20mm Implants

Ø5mm Implants

Drilling procedures

Surgical kit

DSM

Restorative components

Success factors

Keys & Adapters

Insertion System

Packaging

Table of contents.

4.

© MIS Corporation. All rights reserved.

Always dedicated to the development of innovative

products and technologies, MIS' scientists and engineers

conduct continuous laboratory and field studies in

collaboration with prestigious universities and dental

research institutes. C1 is the innovative result of an

extensive research and development process, offering a

unique combination of surgical and restorative benefits.

6.

Advantages.

C1 conical connection implant

All C1 implants, superstructures and tools are color coded to simplify an immediate identification of their platform.

Advantages.

Yellow - indicates a narrow platform

Green - indicates a wide platform

Purple - indicates a standard platform

SurfaceThe surface roughness and micro-morphology combine sand blasting and acid etching. MIS' notable surface technology has provided millions of patients and clinicians with excellent osseointegration results and a long lasting clinical success.

The C1 implantC1 implant benefits from a conical connection with an anti-rotation, six position, cone index. The absolute implant-abutment fastening and the definite seal offered by the conical connection minimize micro-movements and preserve the bone.

Conical shapeWith its conical, root-shaped geometry and a unique thread design, C1 ensures a superior primary stability and offers the ultimate choice for a wide range of clinical cases and loading protocols ▪ Its root-shaped design makes C1 ideal for narrow spaces, restricted by adjacent teeth or implants.

Two spiral channels and domed apexThe two spiral channels at the apical end of the implant, coupled with its self tapping design enable mild direction refinement during the initial stages of insertion ▪ A domed apex allows a safer procedure.

Platform switchingThe C1 system incorporates platform switching by design, allowing the perfect environment for soft-tissue growth and minimizing bone resorption.

Micro ringsMicro rings (0.1x0.3) on the implant’s neck improve the BIC (Bone to Implant Contact) at the crestal zone.

Dual threadA dual thread design increases BIC, reinforcing osseointegration for long lasting clinical success ▪ The overall insertion rate of C1 is 1.5mm per revolution ▪ A self-tapping design and mild bone-compression properties enhance its primary stability.

CC1-00375

CS-HS375CS-HS475CS-HS575CS-HS675

3/4/5/6mm

Ø 4mm

CS-HA375CS-HA475CS-HA575CS-HA675

3/4/5/6mm

Ø 4.4mm

CC1-00500

16mm

16mm

11.50mm

11.50mm

13mm

13mm

8mm

8mm

10mm

10mm

Ø3.75mm

Ø5mm

Ø4.20mm

8.

C1-10375 C1-13375 C1-16375

C1-10420 C1-11420 C1-13420 C1-16420

C1-11375C1-08375

C1-08420

C1-08500 C1-10500 C1-11500 C1-13500 C1-16500

CW-HS350CW-HS450CW-HS550

3/4/5mm

Ø 5mm

3/4/5mm CW-HA350CW-HA450CW-HA550

Ø 5.8mm

Standard PlatformScrew type implant range

Implants cover screw and healing caps.Available in heights: 3,4,5,6mm

Length

Type

Length

Type Implants cover screw and healing caps.Available in heights: 3,4,5mm

Wide PlatformScrew type implant range

Ø 3.10

Ø 3.75

Ø3

Ø 3.60

Ø3.15

1200-1500

900-1200

Ø1.90 Ø3 Ø3.75Ø2.40 Ø2.40

500-700 15-25

Ø3 Ø3.60

200-400

Ø3

C1-08375

C1-16375

C1-10375

C1-11375

C1-13375

Ø3.75mm

Ø3.75mm

Single-use final drill A specially designed final drill for 8mm, 10mm, 11.50mm, 13mm and 16mm implants is supplied with every implant, allowing a short, sterile and safe drilling procedure. This final drill should not be used in type 4 bone.

Standard PlatformCatalog No. Dimensions

Ø 3.75mmlength 8mm

Ø 3.75mmlength 10mm



Ø 3.75mmlength 11.50mm

Implant Procedure

Drilling Speed (RPM)

Diameter

For bonetype 1,2&3

Final drill

* The implant package includes: a cover screw, temporary cylinder and a final drill

The drilling sequence is demonstrated by a 13mm implant.

Procedure recommended by MIS cannot replace the judgment and professional experience of the surgeon.

Do not use the final drill for bone type 4

Titanium Alloy Ti 6Al 4V ELISand Blasted and Acid-Etched

Ø4.20mm

10.

Ø3.50

Ø4

Ø 3.60

Ø 4.20

Ø3.15

C1-08420

C1-16420

C1-10420

C1-11420

C1-13420

Ø4.20mm

1200-1500

900-1200

Ø2.40 Ø3Ø1.90 Ø2.40

500-700

Ø3.50 Ø3.50

400-700

Ø3.50Ø4

200-400

Ø4.20

15-25Drilling Speed (RPM)

Diameter

Ø 4.20mmlength 8mm




Ø 4.20mmlength 11.50mm

For bonetype 1,2&3

Final drill

Implant Procedure


Standard PlatformCatalog No.


Dimensions





Ø4.10 Ø 4.90

200-400

Ø5

15-25

Ø4

400-600

1200-1500

900-1200

Ø2.40 Ø3 Ø3.50Ø2.40Ø1.90

500-700

400-700

Ø5mm

C1-08500

C1-16500

C1-10500

C1-11500

C1-13500

Ø 5

Ø 4.50Ø 4.10

Ø 4.90

Ø4

Ø5mm

Ø4

Drilling Speed (RPM)

Diameter

For bonetype 1,2&3

Final drill

Implant Procedure


Wide Platform

Ø 5mmlength 8mm

Ø 5mmlength 10mm

Ø 5mmlength 13mm

Ø5mmlength 16mm

Ø 5mmlength 11.50mm

Catalog No. Dimensions







Ø3.7

5Ø

4.20

Ø5

C1 IMPLANT

P

ILOT

DRILL

Ø2.4

0mm

PILOT DRILL Ø2.40mm

B

ODY

TRY

IN Ø

2.40m

m BODY TRY IN Ø2.40mm

TW

IST

DRILL

3m

m

TWIST DRILL 3mm

B

ODY

TRY

IN Ø

3mm

TWIST DRILL 3.50mm

TWIST DRILL 3.50mm

FIN

AL D

RILL

BODY TRY IN Ø

3.5mm

BODY TRY IN Ø4mm

FINAL DRILL

SPAD

E / M

ARKI

NG D

RILL

Ø1.9

0mm

SPADE / MARKING DRILL Ø1.90m

m

FINAL DRILL

TWIST DRILL 4mm

TWIST DRILL 3mm

BODY TRY IN Ø2.40mm


SPADE / MARKING DRILL Ø1.90mm

12.


Initial surgical steps are common for all implant diameters. Additional steps are required as the implant's diameter grows.

DrillingProcedures.

Ø3.7

5

Ø4.20

Ø5

C1 IMPLANT

P

ILOT

DRILL

Ø2.4

0mm


B

ODY

TRY

IN Ø

2.40m

m BODY TRY IN Ø2.40mm

TW

IST

DRILL

3m

m

TWIST DRILL 3mm

B

ODY

TRY

IN Ø

3mm

TWIST DRILL 3.50mm

TWIST DRILL 3.50mm

FIN

AL D

RILL

BODY TRY IN Ø

3.5mm

BODY TRY IN Ø4mm

FINAL DRILL

SPAD

E / M

ARKI

NG D

RILL

Ø1.9

0mm

SPADE / MARKING DRILL Ø1.90m

m

FINAL DRILL

TWIST DRILL 4mm

TWIST DRILL 3mm

BODY TRY IN Ø2.40mm


SPADE / MARKING DRILL Ø1.90mm

STANDARD

WIDE

Ø1.90 Ø2.40 Ø3Ø2.40 Ø3 Ø3.50 Ø4Ø4Ø3.50

Procedure Tools Description.

Spade / marking drill Ø1.90mm

Body try in Ø2.40mm for tapered implant procedure

Body try in Ø3mm for tapered implant procedure

Twist drill 3mm, external irrigation

Twist drill 3.50mm, external irrigation

Twist drill 4mm, external irrigation

Final drill

Body try in Ø3.50mm for tapered implant procedure

Body try in Ø4mm for tapered implant procedurePilot drill Ø2.40mm

14.

MK-0044

MT-GDN33

MT-GDN50

MT-BTT24

MT-BTT30

MT-BTT35

MT-RI030

MT-SMD10

MT-TDN30

MT-TDN35

CT-SSI10 CT-SLI10 CT-SDI01

MT-P2408

MT-P2410

With external irrigation drills

Advanced Surgical Instrument Kit.

MT-TDN19

CT-WSI10 CT-WLI10CT-WDI01MT-BTT40 MT-BTT45MT-BTT45 MT-BTT50

MT-SM005

MT-DE001

MT-SHA10

MT-PP240

MT-P2411

MT-P2413

MT-P2416

MT-LM005

MT-SRA10

MT-TDN40

MT-TDT45

MT-TDN50

13.

.

MECHANICAL STABILITY BIOLOGICAL STABILITY

Thanks to a unique drilling methodology,

the implant's geometric design enables a moderate compression of the bone at the top 2/3 of its body. This congestion, enabled by a distinctive conical shaped final drill, provides an immediate and

prolonged mechanical primary stability.

A n e n h a n c e d secondary biological stability

is achieved by integration of the implant's geometry, morphology and

a differential drilling approach. The compartments formed between the implant's threads at the bottom 1/3 of the cavity, generate an ideal habitat

for sustainable bone growth leading to an accelerated

osseointegration.

The Dual Stability Mechanism

(DSM) provided by C1 is based on an integrative development involving the implant’s macro and micro structure as well as a unique differential drilling methodology. C1’s conical design enables

moderate compression of the bone at the coronal 2/3 of the implant's body, providing an immediate mechanical primary stability, while the apical 1/3 of the implant is designed to enable rapid bone growth aimed to minimize stability loss during the first weeks after surgery.

The compartments formed between the threads are a result of the differential drilling approach, which prevents bone compression at the apical section of the implant. The result is an ideal habitat for accelerated and sustainable bone growth and osseointegration, establishing the

Thanks to a unique drilling methodology, the implant's geometric

design enables a moderate compression of the bone at the top 2/3 of its body. This compression, enabled by a distinctive conical shaped final drill, provides

an immediate and prolonged mechanical primary stability.

16.

MECHANICAL STABILITY BIOLOGICAL STABILITY

Thanks to a unique drilling methodology,

the implant's geometric design enables a moderate compression of the bone at the top 2/3 of its body. This congestion, enabled by a distinctive conical shaped final drill, provides an immediate and

prolonged mechanical primary stability.

A n e n h a n c e d secondary biological stability

is achieved by integration of the implant's geometry, morphology and

a differential drilling approach. The compartments formed between the implant's threads at the bottom 1/3 of the cavity, generate an ideal habitat

for sustainable bone growth leading to an accelerated

osseointegration.

implant’s long term biological stability. The DSM mechanism combines benefits of both high primary stability and an accelerated osseointegration process, abridging the way to complete long term stability.

An enhanced secondary biological stability is achieved by

integration of the implant's geometry, morphology and a differential drilling

approach. The compartments formed between the implant's threads at the bottom 1/3 of the cavity generate an ideal habitat for sustainable bone

growth leading to an accelerated osseointegration.

18.

Stoppers

Four sleeves for each diameter in 8, 10, 11.5 and 13mm lengths, color coded according to drills

Box

The tray can be taken out of the box for better convenience

Scale

Teflon OUT Insert

Teflon IN Insert

Simple.

Quick, easy assembly

Kit Contents Ø2.80 stoppers(for Ø3.75mm implants)

Ø3.20 stoppers(for Ø4.20mm implants)

Easy.Color coding for a quick identification of sleeve diameter

Safe. Safe drilling to desired depth

Clear. Clearly arranged depth sleeves for 8 to13mm for two diameters, Ø2.8 and Ø3.2mm

Following the use of MIS' length based pilot drills, the C1 Standard Platform Stoppers Kit ensures drilling to the exact desired depth. The kit includes the most commonly used lengths: 8, 10, 11.5 and 13mm.

Drill Stoppers Kit Standard Platform.

MK-BC101

8mm10mm

11.5mm13mm

MK-CDS08 MK-CDS10

MK-CDS11 MK-CDS13

Simple.

Quick, easy assembly

For 8mm implants For 10mm implants

For 11.5mm implants For 13mm implants

Kit Contents

Scale

Box

Stoppers

The tray can be taken out of the box for better convenience

Five sleeves 3.0, 3.5, 4, 4.5 and 5mm diameters, color coded according to drills

Desireddrilling depth

Teflon OUT Insert

Teflon IN Insert

Easy.Color coding for a quick identification of sleeve diameter

Safe. Safe drilling to desired depth

Clear. Clearly arranged depth sleeves for Ø2.8mm to Ø5mm diameter drills

Following the use of MIS' length based pilot drills, the C1 Drill Stoppers Length Kits enable a safe and easy drilling to the exact desired depth. MIS offers 4 different kits in lengths of: 8, 10, 11.5 and 13mm.

Drill Stoppers Kits Depth Based.

Advantages.

20.

Micro Structure - Surface Morphology

The surface roughness and microgeometry is achieved by sand blasting and acid-etching. A larger surface area increases bone-to-implant contact (BIC), resulting in a long term clinical success.

A high success rate is achieved through a combination of advanced geometric design and our well established surface morphology.

Success.

20

15

10

5

0

Microgram

Implant

Jerusalem, Israel, IADRAugust 03, 2004

Hebrew University

Adsorption of Serum Protein to Modified Titanium SurfacesM.N. Sela, L.Badihi, G.Rosen, D.Kohavi and D. Steinberg

The use of Titanium (Ti) implants is a novel clinical procedure in dentistry. The adsorption of biological molecules to the implant’s surface triggers a sequence of events that may determine the outcome of this procedure. Clinical data suggests that modified Ti surfaces play an important role in the success or failure of the implant. Objective: the purpose of this study was to investigate the interaction between Ti implants with different surface properties and serum proteins, in order to find the optimal implant surfaces which may improve the Osseointegration process and implant intake.

Materials & Methods: Six mm in diameter Ti disks with two types of surface modifications were compared: Machined and Sandblast plus Acid-Etched. The disks were coated with mixtures of Human Serum Albumin conjugated with fluorescein (HAS-FITC).

Following incubation, the coat was removed from the disks by SDS. A Confocal Scanning Laser Microscope was used to visualize and measure the HAS-FITC coat and the degree of protein removal from the Ti surfaces.

Results: The Confocal Microscope images revealed a significantly higher amount of HAS-FITC coat on the rough disks, as compared with the machined disks. Furthermore, under similar experimental conditions, less HAS-FITC could be removed from the rough disks than from the machined disks.

Conclusions: Absorption of albumin to the rough treated Ti surface is both qualitatively and quantitatively far more intense, as compared with the machined surfaces. Further studies of the chemical and physical characterization of the modified Ti surfaces are underway. Moreover, additional serum proteins, as well as oral microorganisms, are being examined for their interactions with the modified Ti surfaces.

Albumin

IGG

Fibronectin

Fibrinogen

Machine

Machine

MIS surface

22.20.22.

MT-SRA10

CT-SLI10

CT-SSI10

MT-SHA10

MT-LM005

MT-SM005

Squ

are

conn

ectio

n to

rat

chet

ada

pter

Han

d w

renc

h sq

uare

con

nect

ion

Long

mot

or a

dapt

er fo

r 0.

05"

hex.

Sho

rt m

otor

ada

pter

for

0.05

" he

x.

Long

inse

rtio

n to

ol, S

P

Sho

rt in

sert

ion

tool

, SP

The C1 mountless implants have their own placement tools. These tools are designed to facilitate quick and reliable implant procedures.

Keys & Adapters.

Standard platform tools shown

13

2

1.

2.

3.

20.

Insertion tool in hand key adapter

Insertion tool for motor

Insertion tool in ratchet adapter

The unique "3 in One" key system minimizes the number of tools in the surgical kit and maximizes flexibility for the user.

"3 in One" Insertion System.

Insertion Options.

24.

Each C1 implant comes with sterilized components for multiple clinical scenarios.

Package Contents.

Cov

er S

crew

Fina

l Dril

l

Insi

de T

ube

Out

side

Tub

e

Impl

ant

13.

Tem

pora

ry C

ylin

der

Following the "Make It Simple" philosophy, MIS is proud to be the first to include a comprehensive tool set which includes: a single use final drill, a cover screw and a temporary cylinder with every C1 implant, meeting all your clinical needs.

12.

Packaging.

Easy pull tab

Implant identification markings

Logical storage

The easily identified pull tab facilitates quick and easy opening during surgery.

The implant's package allows a convenient logical arrangement in its drawer and an immediate identification of the contents.

Quick identification of implant's size and length. A sticker on top of the box, specifies implant's diameter, length and platform size.

Providing a simple indication identification of implant type, length and diameter, the C1 package is well designed for ease of use during surgery.

A double packing system ensures sterilization and safety. Packages are designed for ease of use during surgery and for use with surgical gloves.

Implant diameter & platform indicationThe outer tube is color-coded indicating the implant's platform. The numeric indication specifies the implant's diameter and length.

Platform code Prosthetic platform indicationProsthetic components are marked by specific colors, representing their platforms.

® All rights reserved. No part of this publication may be reproduced, transcribed, stored in an electronic retrieval system, translated into any language or computer language, or be transmitted in any form whatsoever, without the prior written consent of the publisher.

Authorized European Representative:MIS Germany, Paulinenstraße 12a, 32427 Minden, GERMANY

0483

© MIS Corporation. All Rights Reserved.

MIS Implants Technologies Ltdwww.mis-implants.com

MC

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ev.1M

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08 Rev.1

© MIS Corporation. All rights reserved.

MIS’ Quality System complies with international

quality standards: ISO 13485:2003 - Quality

Management System for Medical Devices, ISO

9001: 2008 - Quality Management System and

CE Directive for Medical Devices 93/42/EEC. MIS’

products are cleared for marketing in the USA

and CE approved.MIS Implants Technologies Ltd.www.mis-implants.com

®

MC

-CO

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ev.8

Documents

A Conical Connection Implant3/4/5mm CW-HA350 CW-HA450 CW-HA550 Ø 5.8mm Standard Platform Screw type implant range Implants cover screw and healing caps. Available in heights: 3,4,5,6mm