75 80 60 70 65 55 85 90 95 i n d n e s s H e a r t A t t a c k s o r a b e u o u c h r t b e c l h k o o o e d w d . K i d n r e Pressure exerted by blood on vessel walls. Artery Vessel Blood Lowering your pressure. How various hypertension drugs do their job. Medications and You What is blood pressure? Blood pressure is the force that moves blood through your arteries. Arteries are the blood vessels that carry blood from your heart to the rest of your body. High blood pressure is when your blood pressure is usually higher than it should be. It is also called hypertension. How are medications administered? About 1/2 of people with high 2 or more blood medicines to pressure control their blood pressure. take Blood pressure medication should begin to work within days. Once started, the medication should be used until your doctor tells you to stop. What can occur if not treated? High blood pressure often has no symptoms. It is considered a silent condition. Over time, high blood pressure can cause: in n . B l S t r o k e e y F a i l u T a l k w i t h y o u r d o c o f t e n t o t h a v e p r e s y s u r o Types (Classes) of High Blood Pressure Medicines There are currently nine types of medications that treat high blood pressure: 1. Centrally-Acting Alpha Adrenergics lower blood pressure by decreasing certain chemicals in the blood; therefore, relaxing blood vessels and enabling the heart to beat slowly and easily. 2. Beta Blockers target beta receptors that are found on cells of the heart muscles, smooth muscles, and other tissues. Beta blockers mainly work to weaken the effects of stress hormones on the heart. 3. Calcium Channel Blockers disrupt the movement of calcium through channels into blood vessels and heart cells; allow blood vessels to relax and heart to beat more easily and/or slowly. 4. Peripherally Acting Alpha-Adrenergic Blockers stop hormones from tightening the muscles in the walls of smaller arteries. By causing the aterial vessels to remain open and relaxed, these drugs improve blood flow and lower blood pressure. 5. Vasodilators help widen blood vessels, which results in relaxation of smooth muscle cells within the vessel walls. When blood vessels dilate, the flow of blood is increased due to a decrease in resistance. This dilation of arterial blood vessels decreases blood pressure. 6. Angiotensin-Converting Enzyme (ACE) Inhibitors slow the production of a hormone (angiotens II) that narrows blood vessels, causing dilatio of blood vessels and lowering blood pressure 7. Angiotensin II Receptor Blockers block the effect of the angiotensin II hormon on blood vessels; are alternatives to ACE inhibitor therapy. 8. Renin Inhibitors block the enzyme renin in the ultimate production of angiotensin II. 9. Diuretics (sometimes called water pills) help rid your body of salt and water. They work by making your kidneys put more sodium into your urine. The sodium, in turn, takes water with it from your blood. This decreases the amount of fluid flowing through your blood vessels, which reduces pressure on the walls of your arteries. Combination Medicines These are made up of 2 different kinds of blood pressure drugs. You may have high blood pressure if you are… A smoker Dealing with sleep apnea Physically inactive Older than 50 years Overweight or obese Dealing with diabetes or kidney disease Taking more than 2 grams of sodium per day African American, Hispanic or Latino/Latina A man who drinks more than 1 ounce of alcohol per day A woman who drinks more than half an ounce of alcohol per day A person whose mother or father has hypertension The more areas that describe you, the greater the chance that you may have high blood pressure now or in the future. Sources: 1. U.S. Food and Drug Administration 2. American Society of Hypertension e U.S. Department of Health and Human Services U.S. Food and Drug Administration Center for Drug Evaluation and Research www.fda.gov

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Page 1: 65 blood pressure. Once started, the 60

8590

indness

Heart Attacks

or abe u ou

ch r tb ec l h

k oo oe d wd

Kidn re

Pressure exerted by bloodon vesselwalls

ArteryVessel

Blood

Lowering your pressure How various hypertension drugs do their job

Medications and You

What is blood pressure

Blood pressure is the force that moves

blood through your arteries Arteries

are the blood vessels that carry blood from

your heart to the rest of your body High

blood pressure is when your blood pressure

is usually higher than it should be It is also

called hypertension

How are medications administered About

12 of peoplewith high 2

or more

blood medicines to

pressure control their blood pressure take

Blood pressure medication should begin to work within daysOnce started themedication should be used until your doctor tells you to stop

What can occur if not treatedHigh blood pressure often has no symptoms

It is considered a silent condition

Over time high blood pressure can cause

BlStrokeey Failu

Talk with your docoften to t have pres ysur o

Types (Classes) of High Blood Pressure Medicines There are currently nine types of medications that

treat high blood pressure

1 Centrally-Acting Alpha Adrenergicslower blood pressure by decreasing certain

chemicals in the blood therefore relaxing blood

vessels and enabling the heart to beat

slowly and easily

2 Beta Blockerstarget beta receptors that are found on cells

of the heart muscles smooth muscles and

other tissues Beta blockers mainly work to

weaken the effects of stress hormones on the

heart

3 Calcium Channel Blockersdisrupt the movement of calcium through

channels into blood vessels and heart cells

allow blood vessels to relax and heart to beat

more easily andor slowly

4 Peripherally Acting Alpha-Adrenergic Blockers stop hormones from tightening the muscles in

the walls of smaller arteries By causing the

aterial vessels to remain open and relaxed

these drugs improve blood flow and lower

blood pressure

5 Vasodilators help widen blood vessels which results in

relaxation of smooth muscle cells within the

vessel walls When blood vessels dilate the flow

of blood is increased due to a decrease in

resistance This dilation of arterial blood vessels

decreases blood pressure

6 Angiotensin-Converting Enzyme (ACE) Inhibitors slow the production of a hormone (angiotens

II) that narrows blood vessels causing dilatio

of blood vessels and lowering blood pressure

7 Angiotensin II Receptor Blockersblock the effect of the angiotensin II hormon

on blood vessels are alternatives to ACE

inhibitor therapy

8 Renin Inhibitors block the enzyme renin in the ultimate

production of angiotensin II

9 Diuretics (sometimes called water pills)

help rid your body of salt and water They

work by making your kidneys put more

sodium into your urine The sodium in turn

takes water with it from your blood This

decreases the amount of fluid flowing

through your blood vessels which reduces

pressure on the walls of your arteries

Combination Medicines These are made up of 2 different

kinds of blood pressure drugs

You may have high blood pressure if you arehellipA smoker

Dealing with sleep apneaPhysically inactiveOlder than 50 yearsOverweight or obese

Dealing with diabetes or kidney disease Taking more than 2 grams of sodium per day

African American Hispanic or LatinoLatinaA man who drinks more than 1 ounce of alcohol per dayA woman who drinks more than half an ounce of alcohol per dayA person whose mother or father has hypertension

The more areas that describe you the greater the chance that you may have high blood pressure now or in the future

Sources 1 US Food and Drug Administration2 American Society of Hypertension

US Department of Health and Human ServicesUS Food and Drug AdministrationCenter for Drug Evaluation and Researchwwwfdagov