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2015 Coding Changes Gloria Kirkham CPC, CPC-I, COBGC 317-454-7730 Fax 317-261-2229 1 Disclaimer The information contained in this presentation is intended solely for your personal reference. Such information is subject to change without notice, its accuracy is not guaranteed and it may not contain all material information concerning this topic. The Presenter makes no representation regarding, and assumes no responsibility or liability for, the accuracy or completeness of, or any errors or omissions in, any information contained herein. 2 264 new 143 deleted 134 revised 3 Evaluation and Management 2014 Complex Chronic Care Coordination Services 99487 no face-to-face visit, first hour 99488 one face-to-face visit, first hour 99489 each additional 30 minutes 2015 Care Management Services — New Section heading — Two new subsections — Deletion of code 99488 — Addition of code 99490 4

264 new 2014 Complex Chronic Care Coordination Services ...• Preparation of special reports (code 99080) • Analysis of data (code 99090, 99091) • Transitional care management

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  • 2015Coding Changes

    Gloria Kirkham CPC, CPC-I, COBGC317-454-7730

    Fax317-261-2229

    1

    DisclaimerThe information contained in this presentation is intended solely for your personal reference. Such information is subject to change without notice, its accuracy is not guaranteed and it may not contain all material information concerning this topic. The Presenter makes no representation regarding, and assumes no responsibility or liability for, the accuracy or completeness of, or any errors or omissions in, any information contained herein.

    2

    264 new 143 deleted 134 revised

    3

    Evaluation and Management2014 Complex Chronic Care Coordination Services

    – 99487 no face-to-face visit, first hour– 99488 one face-to-face visit, first hour– 99489 each additional 30 minutes

    2015 Care Management Services— New Section heading— Two new subsections— Deletion of code 99488— Addition of code 99490

    4

  • Evaluation and Management

    • Why were the Chronic Care Management(CCM) Services Created?

    • The goal was to recognize critical non-face-to-face time & services of advanced primary care.

    • Payment is around $40.00-$43.00 (Not released yet)

    5

    Evaluation and Management• Not a per beneficiary/per month

    payment (you must provide the service)• Coinsurance applies• In order to bill

    – Practitioner must inform beneficiary– Obtain written agreement– Must provide beneficiary a copy of the

    plan of care

    6

    Evaluation and ManagementPatients may be identified by practice-specific or other published algorithms that recognize:

    – Multiple illnesses– Multiple medication use– Inability to perform activities of daily living– Requirement for a caregiver, and/or– Repeat admissions or ER visits

    7

    Evaluation and Management

    CCM-Incident to– Modified the policy adopted in CY 2014– Allow incident to billing for CCM with

    “general supervision” when services provided by clinical staff

    – CFR 410.26

    8

  • Evaluation and Management

    Care Management Services– Provided by clinical staff, under the

    direction of a physician or other QHP (Qualified Healthcare Provider)

    – New code allows reporting for patients receiving at least 20 minutes of clinical staff time spent per calendar month.

    • (Full Minutes, no ½)

    9

    Evaluation and Management

    To patients who reside:– At home– Domiciliary– Rest home– Assisted living facility

    10

    Evaluation and ManagementManagement and support services may include:

    – Establishing– Implementing– Revising– Monitoring– Coordinating the care of other professionals and

    agencies– Educating the patient or caregiver about the

    patient’s condition, care plan, and prognosis

    11

    Evaluation and Management

    The Physician or QHP, provides or oversees the management and/or coordination of services, as needed, for all medical conditions, psychosocial needs, and is instrumental in the basic activities of daily living.

    12

  • Evaluation and Management

    A patient’s care plan is a comprehensive plan of care for all health problems, which is based on a physical, mental, cognitive, social, functional, and environmental assessment of the patient.

    13

    Evaluation and Management

    Typically include/not all inclusive– Patient’s problem list, with expected outcome

    and prognosis– Measurable treatment goals– Symptom management– Planned interventions– Medication management

    14

    Evaluation and Management

    – Community and/or social services ordered, and how the services of agencies and specialists not connected to the practice will be directed and/or coordinated

    – Identification of individuals responsible for each intervention

    – Requirement for periodic review, and, when applicable, revision of the care plan

    15

    Evaluation and Management

    CPT Codes 99487-99490 are reported only once per calendar month and may only be reported by the single physician or QHP who assumes the care management role with a particular patient for a the calendar month

    16

  • Evaluation and Management

    Codes 99487-99489 are not reported if chronic care management services are performed within the postoperative period of a reported surgery performed by the same individual.

    17

    Evaluation and Management• Determining the clinical staff time spent in

    performance of CCM Services for the month– Face to face time

    • Spent with the patient and/or family, caregivers, other professionals, and agencies

    – Non-face to face timeRevising, documenting, and implementing the care plan

    18

    Evaluation and Management

    • Only clinical staff can count time• When two or more clinical staff

    members are meeting about the patient, only count the time of one clinical staff member.

    19

    Evaluation and Management

    • On the first visit do not count that time

    • On days that an E/M service is reported do not count that time– 99201-99215; 99324-99337; 99341-

    99350

    20

  • Evaluation and Management• The care management office/practice

    must have the following capabilities:– Provide 24/7 access to physicians or other QHP or clinical

    staff including providing patients and caregivers with a means to make contact with health care professionals in the practice to address urgent needs regardless of the time of day or day of the week

    – Provide continuity of care with a designated member of the care team with whom the patient is able to schedule successive routine appointments

    21

    Evaluation and Management– Provide timely access and management

    for follow-up after an ER visit or facility discharge

    – Use an electronic health record system so that care providers have timely access to clinical information

    – Use a standardized methodology to identify patients who require care management services

    22

    Evaluation and Management– Have an internal care management process

    or function whereby a patient identified as meeting and requirements for these services starts receiving them in a timely manner

    – Use a form and format in the medical record that is standardized within the practice

    – Be able to engage and educate patients and caregivers as well as coordinate care among all service professionals, as appropriate for each patient

    23

    Evaluation and Management• Additional E/M services may be reported

    separately by the same physician or QHP during the same calendar month by using the appropriate E/M codes).

    • However the following services are integral to the performance of care management services (codes 99487-99490)

    24

  • Evaluation and Management• Care plan oversight services (codes

    99339, 99340, 99374-99380)• Prolonged services without direct

    patient contact (codes 99358-99359) • Anticoagulant management (codes

    99363, 99364)

    25

    Evaluation and Management• Medical team conference (codes 99366,

    99368)• Education and training (codes 98960-

    98962, 99071, 99078)• Telephone services (codes 98966-98968,

    99441-99443)• On-line medical evaluation (codes 98969,

    99444)

    26

    Evaluation and Management• Preparation of special reports (code 99080)• Analysis of data (code 99090, 99091)• Transitional care management services

    (codes 99495, 99496)• Medication therapy management services

    (codes 99605-99607)• End stage renal disease services (codes

    90951-90970)

    27

    Evaluation and Management

    • 99490 CCM services, at least 20 minutes of clinical staff time directed by a physician or other QHP, per month, with the following required elements:– Multiple (two or more) chronic conditions

    expected to last at least 12 months, or until the death of the patient

    28

  • Evaluation and Management– Chronic conditions place the patient at

    significant risk of death, acute exacerbation/decompensation, or functional decline

    – Comprehensive care plan established, implemented revised, or monitored

    – If less than 20 minutes duration in a calendar month is spent, this service is not reported separately

    29

    Evaluation and Management• 99487 Complex Chronic Care Management

    Services, required elements– Multiple (two or more) chronic conditions

    expected to last at least 12 months, or until the death of the patient

    – Chronic conditions place the patient at significant risk of death, acute exacerbation/ decompensation, or functional decline

    30

    Evaluation and Management• Establishment or substantial revision

    of a comprehensive care plan• Moderate or high complexity medical

    decision making• 60 minutes of clinical staff time

    directed by a physician or QHP, per calendar month

    31

    Evaluation and Management

    • +99489 Each additional 30 minutes of clinical staff time directed by a QHP per calendar month (List separately in addition to code for primary procedure)

    • 99488 has been deleted. To report one or more face-to-face visits by the physician or QHP that are performed in the same month as 99487, use the appropriate E/M code

    32

  • Evaluation and ManagementNOTE: Physicians or QHP may not report complex care management services if the care plan is unchanged or requires minimal change (eg. Only a medication is changed or an adjustment in a treatment modality is ordered)

    33

    Evaluation and ManagementTypical adult patients who receive complex chronic care management services are treated with three or more prescription medications and may be receiving other types of therapeutic interventions (eg, physical therapy, occupational therapy).

    34

    Evaluation and Management

    Typical pediatric patients receive three or more therapeutic intervention (eg, medications, nutritional support, respiratory therapy).

    35

    Evaluation and Management99497 Advance care planning including the explanation and discussion of advance directives such as standard forms (with completion of forms, when performed), by the physician or QHP; first 30 minutes, face-to-face with the patient, family member(s), and/or surrogate

    36

  • Evaluation and Management

    +99498 each additional 30 minutes (List separately in addition to code for primary procedure)

    37

    Evaluation and ManagementAdvance Care Planning; are used to report the face-to-face service between a physician or QHP and a patient, family member, or surrogate in counseling and discussing advance directives, with or without completing relevant legal forms.

    38

    Evaluation and ManagementAn advance directive is a document appointing an agent and/or recording the wishes of a patient pertaining to his/her medical treatment at a future time should he/she lack decisional capacity at that time.

    39

    Evaluation and ManagementExamples of written advance directives include, but are not limited to Health Care Proxy, Durable Power of Attorney for Health Care Living Will, and Medical Orders for Life-Sustaining Treatment (MOLST)

    40

  • Evaluation and Management

    When using codes 99497, 99498, no active management of the problem(s) is undertaken during the time period reported.

    41

    Evaluation and ManagementSpecific Modifiers for Distinct

    Procedural Services http://www.cms.gov/Outreach-and-Education/Medicare-Learning-Network-MLN/MLNMattersArticles/Downloads/MM8863.pdfMLN Matters® Number: MM8863

    42

    Evaluation and Management

    • Release Date: August 15, 2014

    • Effective Date: January 1, 2015

    • Implementation Date: January 5, 2015

    43

    Evaluation and ManagementContractors shall use the following as the definition for the CR implementation date:

    The implementation date identified in a change request is the date by which Medicare fee-for- service contractors shall apply all changes detailed in the business requirements, unless otherwise specified. It is the date when all necessary updates to infrastructure, business processes and/or supporting technology changes shall be completed and operational in order to execute new/modified policy and procedure.

    Note: Implementation dates and effective dates are frequently not the same day. The Implementation date is the same for all business requirement(s) listed within a specific CR, unless otherwise specified.

    Contractors shall use the following as the definition for CR effective date:

    The effective date identified in a change request is the date on which any new rules, laws, processes and/or policies become active.

    44

  • Evaluation and Management

    (CMS) is establishing four new HCPCS modifiers to define subsets of the -59 modifier, a modifier used to define a “Distinct Procedural Service.”

    45

    Evaluation and Management• The primary issue associated with the -59

    modifier is that it is defined for use in a wide variety of circumstances, such as to identify:

    • Different encounters; • Different anatomic sites; and • Distinct services.

    46

    Evaluation and Management• The -59 modifier is • Infrequently (and usually correctly) used to

    identify a separate encounter; • Less commonly (and less correctly) used to

    define a separate anatomic site; and • More commonly (and frequently incorrectly)

    used to define a distinct service.

    47

    Evaluation and Management

    CMS believes that more precise coding options coupled with increased education and selective editing is needed to reduce the errors associated with this overpayment.

    48

  • Evaluation and Management• XE Separate Encounter, A Service That Is Distinct Because It

    Occurred During A Separate Encounter, • XS Separate Structure, A Service That Is Distinct Because It

    Was Performed On A Separate Organ/Structure, • XP Separate Practitioner, A Service That Is Distinct Because It

    Was Performed By A Different Practitioner, and • XU Unusual Non-Overlapping Service, The Use Of A Service

    That Is Distinct Because It Does Not Overlap Usual Components Of The Main Service.

    49

    Evaluation and ManagementCMS will continue to recognize the -59 modifier, but notes that Current Procedural Terminology (CPT) instructions state that the -59 modifier should not be used when a more descriptive modifier is available. While CMS will continue to recognize the -59 modifier in many instances, it may selectively require a more specific - X{EPSU} modifier for billing certain codes at high risk for incorrect billing.

    50

    Evaluation and ManagementFor example, a particular NCCI PTP code pair may be identified as payable only with the -XE separate encounter modifier but not the -59 or other -X{EPSU} modifiers. The -X{EPSU} modifiers are more selective versions of the -59 modifier so it would be incorrect to include both modifiers on the same line.

    51

    Musculoskeletal System

    20600 Arthrocentesis, aspiration and/or injection, small joint or bursa (eg, fingers, toes), without ultrasound guidance

    20604 with ultrasound guidance, with permanent recording and reporting

    – (Do not report 20600, 20604 in conjunction with 76942)

    52

  • Musculoskeletal System

    20605 Arthrocentesis, aspiration and/or injection, intermediate joint or bursa (eg, temporomandibular, wrist, elbow or ankle, olecranon bursa); without ultrasound guidance

    20606 with ultrasound guidance, with permanent recording and reporting.

    – (Do not report 20605, 20606 in conjunction with 76942)

    53

    Musculoskeletal System20610 Arthrocentesis, aspiration and/or

    injection, major joint or bursa (eg, shoulder, hip, knee, subacromial bursa); without ultrasound guidance

    20611 with ultrasound guidance, with permanent recording and reporting

    – (Do not report 20610, 20611 in conjunction with 27370, 76942)

    54

    Musculoskeletal System21811 Open treatment of rib

    fracture(s) with internal fixation includes thoracoscopic visualization when performed unilateral/ 1-3 ribs

    21812 4-6 ribs21813 7 or more ribs

    For bilateral procedure, report with modifier 50

    55

    Musculoskeletal System22510 Percutaneous vertebroplasty

    (bone biopsy included when performed), 1 vertebral body, unilateral or bilateral injection, inclusive of all imaging guidance cervicothoracic

    22511 lumbosacral+22512each additional cerviothoracic or

    lumbosacral vertebral body (List separately in addition to code for primary procedure)

    56

  • Musculoskeletal System22513 Percutaneous vertebral

    augmentation, including cavity creation (fracture reduction and bone biopsy included when performed) using mechanical device (eg, kyphoplasty(, 1 vertebral body, unilateral or bilateral cannulation, inclusive of all imaging guidance; thoracic

    22514 lumbar+22515 each additional thoracic

    or lumbar vertebral body (List separately in addition to code for primary procedure)

    57

    Musculoskeletal System27279 Arthrodesis, sacroiliac joint,

    percutaneous or minimally invasive (indirect visualization), with image guidance, includes obtaining bone graft when performed, and placement of transfixing device

    27280 Arthrodesis, open, sacroiliac joint, including obtaining bone graft, including instrumentation, when performed

    For bilateral procedures report modifier 50

    58

    Cardiovascular System

    Category III codes 0319T-0328T related to subcutaneous implantable defibrillator procedures have been deleted and replaced with 33270-33273

    59

    Cardiovascular System#33270 Insertion or replacement of

    permanent subcutaneous implantable defibrillator system, with subcutaneous electrode, including defibrillation threshold evaluation, induction of arrhythmia, evaluation of sensing for arrhythmia termination, and programming or reprogramming of sensing or therapeutic parameters, when performed.

    60

  • Cardiovascular System#33271 Insertion of subcutaneous

    implantable defibrillator electrode#33272 Removal of subcutaneous

    implantable defibrillator electrode#33273 Repositioning of previously

    implanted subcutaneous implantable defibrillator electrode

    61

    Cardiovascular SystemNew subsection:Extracorporeal Membrane Oxygenation or Extracorporeal Life Support ServicesECMO and /or ECLS procedures

    New Introductory guidelines

    New Family of codes 33946-33989

    62

    Cardiovascular SystemCodes 33960 and 33961 were originally developed for use in the neonatal population for severe postpartum respiratory insufficiency, However this treatment has evolved and is now being provided to a variety of adults with severe influenza, pneumonia, and respiratory distress syndrome, as well as to pediatric patients.

    63

    Cardiovascular System

    As a result, codes 33960, 33961, and 36822 have been deleted, and the Cardiac Assist guidelines have been revised to remove reference to deleted code 36822.

    64

  • Cardiovascular System

    ECMO/ECLS is a procedure that provides cardiac and/or respiratory support to the heart and/or lungs, which allows them to rest and recover when sick or injured.

    65

    Cardiovascular SystemECMO/ECLS supports the function of the heart and/or lungs by continuously pumping some of the patient’s blood out of the body to an oxygenator where oxygen is added to the blood, carbon dioxide is removed, and the blood is warmed before it is returned to the patient.

    66

    Cardiovascular SystemThere are two methods that can be used to accomplish ECMO/ECLS.One method is Venoarterialextracorporeal life support, which supports both the heart and the lungs. Venoarterial ECMO/ECLS requires that two cannulae are placed: one in a large vein and one in a large artery.

    67

    Cardiovascular SystemThe other method is Venovenousextracorporeal life support, Venovenous ECMO/ECLS is used for lung support only and requires one or two cannula(e), which are placed in a vein.

    68

  • Cardiovascular SystemThe insertion, repositioning, and the removal of the cannula(e) are surgical procedures that can be performed percutaneously, open or by sternotomyor thoracotomy approach and are done on different days.

    69

    Cardiovascular System

    Codes 33946-33989 will facilitate proper reporting of physician work and allow the appropriate professionals who are involved in the treatment of these complex patients to report their services.

    70

    Cardiovascular SystemCodes 33946 and 33947 describe the initial insertion of the cannulation of the ECMO/ECLS circuit and setting of parameters performed by the physician, which involves determining the necessary ECMO/ECLS device components, blood flow, gas exchange, and other necessary parameters to manage the circuit. For insertion of a cannulation for extracorporeal circulation, report codes 33951-33956

    71

    Cardiovascular SystemCodes 33948 and 33949 describe the daily management of the ECMO/ECLS circuit and monitoring parameters requiring physician oversight to ensure that specific features of the interaction of the circuit with the patient are met. ECMO therapy is very invasive and requires constant one-on-one monitoring, assessment, and adjustments.

    72

  • Cardiovascular SystemIt would not be appropriate to append modifier 63 to 33946-33949. It would also not be appropriate to report the daily management codes 33948 and 33949 on the same day in conjunction with the initiation codes 33946 and 33947

    73

    Cardiovascular System

    For more information on these codes see the manual provided.

    74

    Digestive SystemIn 2014 CPT code set, the Esophagus/Endoscopy section was restructured into three subsections: Esophagoscopy, Esophagogastroduodenoscopy (EGD), and Endoscopic Retrograde Cholangiopancreatography(ERCP). In those subsections, the codes were revised, deleted, and added to bundle services that were commonly performed together and to describe current practice more accurately.

    75

    Digestive SystemIn the 2015 CPT code set, changes have been made to the Intestines and Rectum Endoscopy subsections for the same purposes. A Colonoscopy decision tree has been added to help users select the appropriate colonoscopy code.

    76

  • Decision to undergo 

    Colonoscopy

    Diagnostic Procedure

    Does Not Reach Splenic Flexure

    Flexible Sigmoidoscopy 

    (45330)

    Beyond Splenic Flexure, But Not To the Cecum

    Colonoscopy (45378; Modifier 

    53)

    To Cecum

    Colonoscopy (45378, No Modifier)

    Therapeutic Procedure

    Does Not Reach Splenic Flexure

    Flexible Sigmoidoscopy (45331‐45347)

    Beyond Splenic Flexure, But Not To the Cecum

    Colonoscopy (45379‐45398; Modifier 52)

    To Cecum

    Colonoscopy (45379‐45398; No Modifier)

    77

    Digestive SystemDefinition of Colonoscopy –RevisedColonoscopy Is the examination of the entire colon, from the rectum to the cecum, and may include the examination of the terminal ileum or small intestine proximal to an anastomosis

    78

    Digestive SystemDefinition of Colonoscopy through StomaColonoscopy through Stoma is now defined as the examination of the colon, from the colostomy stoma to the cecum or colon-small intestine anastomosis, and may include examination of the terminal ileum or small intestine proximal to an anastomosis

    79

    Digestive System

    Definition of ProctosigmoidoscopyProctosigmoidoscopy is the examination of the rectum and may include examination of a portion of the sigmoid colon

    80

  • Digestive System

    Definition of SigmoidoscopySigmoidoscopy is the examination of the entire rectum, sigmoid colon and may include examination of a portion of the descending colon.

    81

    Digestive System2014 CPT Code

    2015 HCPCS Code

    Long Descriptor

    44383 G6018 Ileoscopy, through stoma; with transecdoscopic stent placement (includes predilation)

    44393 G6019 Colonoscopy through stoma; with ablation of tumor(s), polyp(s), or other lesion(s) not amenable to removal by hot biopsy forceps, bipolar cautery or snare technique

    44397 G6020 Colonoscopy through stoma; with transendoscopicstent placement (includes predilation)

    44799 G6021 Unlisted procedure, intestine

    82

    Digestive System2014 CPT Code

    2015 HCPCS Code

    Long Descriptor

    45339 G6022 Sigmoidoscopy, flexible; with ablation of tumor(s), polyp(s), or other lesion(s) not amenable to removal by hot biopsy forceps, bipolar cautery or snare technique

    45345 G6023 Sigmoidoscopy, flexible; with transendoscopic stent placement (includes predilation)

    45383 G6024 Colonoscopy, flexible, proximal to splenic 

    45387 G6025 Colonoscopy, flexible, proximal to splenic flexure; with transendoscopic stent placement (includes predilation)

    83

    Digestive System2014CPT Code

    2015 HCPCS Code

    Long Descriptor

    0226T G6025 Anoscopy, high resolution (HRA) (with magnification and chemical agent enhancement); diagnostic, including collection of specimen(s) by brushing or washing when performed

    0227T G6027 Anoscopy, high resolution (HRA) (with magnification and chemical agent enhancement); with biopsy(ies)

    84

  • Digestive SystemIf the patient is Medicare (Original, Medicare Advantage), and :

    – If the code has not changed from 2014 to 2015

    – Physicians report the CPT code

    – If the code has changed from 2014 to 2015

    – Physicians report the G code

    – If the code is new for 2015– Physicians report the CPT code

    85

    Digestive SystemStent placement:New codes include pre- and post-dilation and guide wire passage.Use 74360 if fluoroscopic guidance is performed.

    86

    Digestive SystemStent Placement OLD NEW

    Colonoscopy through Stoma

    44397 44402

    Flexible Sigmoidoscopy

    45345 45347

    Colonoscopy 45387 45389

    87

    Digestive SystemEndoscopic Mucosal Resection

    Not separately reportable with biopsy, submucosal injection, snare, or band ligation for the same lesion. (Now included)

    88

  • Digestive SystemBalloon Dilation of multiple strictures can be reported with modifier 59 for each additional stricture dilatedUse 74360 if fluoroscopic guidance is performed(Not separately reportable with ablation or stent placement procedures)

    89

    Digestive SystemBottom line: If 2 or more procedures are reported together 75% of the time it is likely they are or will be bundled.

    Review this section in detail

    90

    Digestive SystemEffective January 1, 2015, Anesthesia professionals who furnish a separately payable anesthesia service in conjunction with a colorectal cancer screening test should include the 33 modifier on the claim line with the anesthesia service.(At the time of preparing this presentation a Change Request (CR) has not been released. Please watch for it).

    91

    Urinary System

    52441Cystourethroscopy, with insertion of permanent adjustable transprostatic implant; single implant

    +52442 each additional permanent adjustable transprostaticimplant (List separately in addition to code for primary procedure)

    92

  • Nervous System4 new bundled codes have been added for myelography procedures 62302 Myelography via lumbar injection,

    including radiological supervision and interpretation; cervical

    62302 thoracic62304 lumbosacral62305 2 or more regions (eg,

    lumbar/lhoracic, cervical/thoracic, lumbar/cervical, lumbar/thoracic/cervical)

    93

    Nervous SystemThe existing injection and radiological supervision and interpretation codes for myelography (77240, 77255, 77265, and 72270) have been retained.These procedures are occasionally performed by two physicians; one performs the contrast injection and the second provides the radiological supervision and interpretation.

    94

    Nervous System4 codes have been established to report administration of local anesthetic for postoperative pain control and abdominal wall analgesia, including imaging guidance when performed.

    95

    Nervous System64486 Transverus abdominis plane (TAP)

    block (abdominal plane block, rectus sheath block) unilateral by injection(s) i(includes imaging guidance, when performed)

    64487 by continuous infusion(s) (includes imaging guidance when performed)

    64488 Transversus abdominis plane (TAP) block (abdominal plane block, rectus sheath block) bilateral, by injections (includes imaging guidance, when performed)

    64489 by continuous infusions (includes imaging guidance, when performed)

    96

  • Nervous SystemBecause more than 50% of the time these services are typically performed bilaterally, codes 64486 and 64487are intended to report the transversusabdominis plane (TAP) block performed unilaterally, and codes 64488 and 64489 are intended to report bilateral services

    97

    Radiology/Diagnostic UltrasoundCode 76641 is intended to describe a complete ultrasound examination of all four quadrants of the breast, the retroareolar region, and the axilla when performed.

    98

    Radiology/Diagnostic Ultrasound

    Code 76642 is intended to describe a focused ultrasound examination of the breast, with a limited assessment of one or more of the elements included in code 76641, but not all, and of the axilla when performed.

    99

    Radiology/Diagnostic Ultrasound

    Codes 76641 and 76642 should be reported only once per breast per session.

    100

  • Radiology/Diagnostic Ultrasound

    Mamography77061, 77062, and 77063 have been established to report diagnostic and screening breast tomosynthesis, unilateral and bilateral procedure.

    101

    Radiology/Diagnostic UltrasoundBreast tomosynthesis is a digital tomographic, technique performed using multiple low-dose X-ray exposures, which are obtained as the X-ray tube swings in an arc around the compressed breast. The resulting image-data are reconstructed using standard computer algorithms to produce a series of sequential stacked slices through the breast.

    102

    Radiology/Diagnostic Ultrasound77061 Digital breast tomosynthesis;

    unilateral77062 bilateral+77063 Screening digital breast

    tomosynthesis, bilateral (List separately in addition to code for primary procedure)(Use 77063 in conjunction with 77057)

    103

    Radiology/Diagnostic Ultrasound77080 and 77082 has been identified as being reported 75% of the time. As a result, code 77082 has been deleted and new code 77085, which bundles the bone density study and vertebral fracture assessment, was created, In addition, code 77086 was created to report vertebral fracture assessment via DXA.

    104

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    .

    Sec

    ondl

    y, n

    ew c

    odes

    77316, 77317, 77318

    have

    bee

    n es

    tabl

    ishe

    d to

    rep

    ort

    com

    bine

    d br

    achy

    ther

    apy

    isod

    ose

    plan

    ning

    with

    bas

    ic

    dosi

    met

    ry c

    alcu

    latio

    n(s)

    .

    106

  • 2015

    CPT

    Cod

    ing

    Upd

    ates

    Glo

    ria K

    irkha

    m C

    PC, C

    PC-I,

    CO

    BG

    C

    gkirk

    ham

    @is

    man

    et.o

    rg

    Indi

    ana

    Sta

    te M

    edic

    al A

    ssoc

    iatio

    n 32

    2 C

    anal

    Wal

    k In

    dian

    apol

    is In

    dian

    a 46

    202

  • Tabl

    e of

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    tent

    s

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    uatio

    n an

    d M

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    t ....

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    thol

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    .. 15

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    1

    Eval

    uatio

    n an

    d M

    anag

    emen

    t

    # 9

    9490 C

    hron

    ic c

    are

    man

    agem

    ent

    serv

    ices

    , at

    lea

    st 2

    0 m

    inut

    es o

    f cl

    inic

    al s

    taff

    tim

    e di

    rect

    ed b

    y a

    phys

    icia

    n or

    oth

    er q

    ualif

    ied

    heal

    th c

    are

    prof

    essi

    onal

    . Pe

    r ca

    lend

    ar m

    onth

    , w

    ith t

    he f

    ollo

    win

    g re

    quire

    d el

    emen

    ts.

    Mul

    tiple

    (tw

    o or

    mor

    e) c

    hron

    ic c

    ondi

    tions

    exp

    ecte

    d to

    last

    at

    leas

    t 12 m

    onth

    s, o

    r un

    til t

    he d

    eath

    of

    the

    patie

    nt;

    C

    hron

    ic

    cond

    ition

    s pl

    ace

    the

    patie

    nt

    at

    sign

    ifica

    nt

    risk

    of

    deat

    h,

    acut

    e ex

    acer

    batio

    n/de

    com

    pens

    atio

    n, o

    r fu

    nctio

    nal d

    eclin

    e;

    C

    ompr

    ehen

    sive

    car

    e pl

    an e

    stab

    lishe

    d, im

    plem

    ente

    d, r

    evis

    ed,

    or m

    onito

    red.

    (C

    hron

    ic c

    are

    man

    agem

    ent se

    rvic

    es o

    f le

    ss tha

    n 20 m

    inut

    es d

    urat

    ion,

    in a

    cal

    enda

    r m

    onth

    , ar

    e no

    t re

    port

    ed s

    epar

    atel

    y)

    Cod

    es 9

    9487,

    99489,

    99490 a

    re r

    epor

    ted

    only

    onc

    e pe

    r ca

    lend

    ar m

    onth

    and

    may

    onl

    y be

    re

    port

    ed b

    y th

    e si

    ngle

    phy

    sici

    an o

    r ot

    her qu

    alifi

    ed h

    ealth

    car

    e pr

    ofes

    sion

    al w

    ho a

    ssum

    es t

    he c

    are

    man

    agem

    ent

    role

    with

    a p

    artic

    ular

    pat

    ient

    for

    the

    cal

    enda

    r m

    onth

    .

    Car

    e m

    anag

    emen

    t se

    rvic

    es a

    re m

    anag

    emen

    t an

    d su

    ppor

    t se

    rvic

    es p

    rovi

    ded

    by c

    linic

    al s

    taff

    , und

    er

    the

    dire

    ctio

    n of

    a p

    hysi

    cian

    or

    othe

    r qu

    alifi

    ed h

    ealth

    car

    e pr

    ofes

    sion

    al,

    to a

    pat

    ient

    res

    idin

    g at

    ho

    me

    or in

    a d

    omic

    iliar

    y, r

    est

    hom

    e, o

    r as

    sist

    ed li

    ving

    fac

    ility

    .

    Do

    not

    coun

    t an

    y cl

    inic

    al s

    taff

    tim

    e on

    a d

    ay w

    hen

    the

    phys

    icia

    n or

    qua

    lifie

    d he

    alth

    car

    e pr

    ofes

    sion

    al r

    epor

    ts a

    n E/

    M s

    ervi

    ce.

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    2

    9

    9487 C

    ompl

    ex c

    hron

    ic c

    are

    man

    agem

    ent

    serv

    ices

    , w

    ith t

    he f

    ollo

    win

    g re

    quire

    d el

    emen

    ts:

    Mul

    tiple

    (tw

    o or

    mor

    e) c

    hron

    ic c

    ondi

    tions

    exp

    ecte

    d to

    last

    at

    leas

    t 12 m

    onth

    s,

    or u

    ntil

    the

    deat

    h of

    the

    pat

    ient

    ;

    Chr

    onic

    co

    nditi

    ons

    plac

    e th

    e pa

    tient

    at

    si

    gnifi

    cant

    ris

    k of

    de

    ath,

    ac

    ute

    exac

    erba

    tion/

    deco

    mpe

    nsat

    ion,

    or

    func

    tiona

    l dec

    line;

    Com

    preh

    ensi

    ve c

    are

    plan

    est

    ablis

    hed,

    impl

    emen

    ted,

    rev

    ised

    , or

    mon

    itore

    d.

    M

    oder

    ate

    or h

    igh

    com

    plex

    ity m

    edic

    al d

    ecis

    ion

    mak

    ing

    60 m

    inut

    es o

    f cl

    inic

    al s

    taff

    tim

    e di

    rect

    ed b

    y a

    phys

    icia

    n or

    oth

    er q

    ualif

    ied

    heal

    ca

    re p

    rofe

    ssio

    nal,

    per

    cale

    ndar

    mon

    th

    +

    99489 e

    ach

    addi

    tiona

    l 30 m

    inut

    es o

    f cl

    inic

    al s

    taff

    tim

    e di

    rect

    ed b

    y a

    phys

    icia

    n or

    oth

    er q

    ualif

    ied

    heal

    th c

    are

    prof

    essi

    onal

    , pe

    r ca

    lend

    ar m

    onth

    (Li

    st s

    epar

    atel

    y in

    ad

    ditio

    n to

    cod

    e fo

    r pr

    imar

    y pr

    oced

    ure)

    (Rep

    ort

    99489 in

    con

    junc

    tion

    with

    99487)

    AD

    VA

    NC

    E C

    ARE

    PLA

    NN

    ING

    99497 A

    dvan

    ce c

    are

    plan

    ning

    incl

    udin

    g th

    e ex

    plan

    atio

    n an

    d di

    scus

    sion

    of

    adva

    nce

    dire

    ctiv

    es s

    uch

    as s

    tand

    ard

    form

    s (

    with

    com

    plet

    ion

    of f

    orm

    s, w

    en p

    erfo

    rmed

    ), b

    y th

    e ph

    ysic

    ian

    or Q

    HP;

    firs

    t 30 m

    inut

    es,

    face

    -to-

    face

    with

    the

    pat

    ient

    , fa

    mily

    m

    embe

    r(s)

    , an

    d/or

    sur

    roga

    te

    +99498

    ea

    ch a

    dditi

    onal

    30 m

    inut

    es (

    List

    sep

    arat

    ely

    in a

    dditi

    on t

    o co

    de f

    or p

    rimar

    y pr

    oced

    ure)

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    3

    Mus

    culo

    skel

    etal

    Sys

    tem

    TRIG

    GER

    PO

    INT IN

    JEC

    TIO

    N

    20600 A

    rthr

    ocen

    tesi

    s, a

    spira

    tion

    and/

    or inj

    ectio

    n, s

    mal

    l jo

    int

    or b

    ursa

    (eg

    , fing

    ers,

    toe

    s),

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    out

    ultr

    asou

    nd g

    uida

    nce

    20604 W

    ith u

    ltras

    ound

    gui

    danc

    e, w

    ith p

    erm

    anen

    t re

    cord

    ing

    and

    repo

    rtin

    g

    (D

    o no

    t re

    port

    20600, 20604 in

    con

    junc

    tion

    with

    76942)

    20605

    Art

    hroc

    ente

    sis,

    as

    pira

    tion

    and/

    or

    inje

    ctio

    n,

    inte

    rmed

    iate

    jo

    nt

    or

    burs

    a (e

    g,

    tem

    poro

    man

    dibu

    lar,

    wris

    t, e

    lbow

    or

    ankl

    e, o

    lecr

    anon

    bur

    sa); w

    ithou

    t ul

    tras

    ound

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    danc

    e

    20606 W

    ith u

    ltras

    ound

    gui

    danc

    e, w

    ith p

    erm

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    t re

    cord

    ing

    and

    repo

    rtin

    g.

    (Do

    not

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    rt 2

    0605, 20606 in

    con

    junc

    tion

    with

    76942)

    20610 A

    rthr

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    tesi

    s, a

    spira

    tion

    and/

    or in

    ject

    ion,

    maj

    or jo

    int

    or b

    ursa

    (eg

    , sh

    ould

    er,

    hip,

    kn

    ee, su

    bacr

    omia

    l bur

    sa);

    with

    out

    ultr

    asou

    nd g

    uida

    nce

    20611 W

    ith u

    ltras

    ound

    gui

    danc

    e, w

    ith p

    erm

    anen

    t re

    cord

    ing

    and

    repo

    rtin

    g

    (D

    o no

    t re

    port

    20610, 20611 in

    con

    junc

    tion

    with

    27370, 76942)

    OTH

    ER P

    RO

    CED

    URES

    20982 A

    blat

    ion

    ther

    apy

    for

    redu

    ctio

    n or

    era

    dica

    tion

    of 1

    or

    mor

    e bo

    ne t

    umor

    s (e

    g,

    met

    asta

    sis)

    incl

    udin

    g ad

    jace

    nt s

    oft

    tissu

    e w

    hen

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    lved

    by

    tum

    or e

    xten

    sion

    , pe

    rcut

    aneo

    us, in

    clud

    ing

    imag

    ing

    guid

    ance

    whe

    n pe

    rfor

    med

    , ra

    diof

    requ

    ency

    20983

    Cry

    obla

    tion

    FRA

    CTU

    RE

    AN

    D/O

    R D

    ISLO

    CA

    TIO

    N

    21811 O

    pen

    trea

    tmen

    t of

    rib

    fra

    ctur

    e(s)

    with

    inte

    rnal

    fix

    atio

    n in

    clud

    es t

    hora

    cosc

    opic

    vi

    sual

    izat

    ion

    whe

    n pe

    rfor

    med

    uni

    late

    ral/

    1-3

    rib

    s

    21812

    4-6

    rib

    s

    21813

    7 o

    r m

    ore

    ribs

    PERC

    UTA

    NEO

    US V

    ERTEB

    RO

    PLA

    STY

    AN

    D V

    ERTEB

    RA

    L A

    UG

    MEN

    TA

    TIO

    N

    22510 P

    ercu

    tane

    ous

    vert

    ebro

    plas

    ty (bo

    ne b

    iops

    y in

    clud

    ed w

    hen

    perf

    orm

    ed), 1

    ver

    tebr

    al b

    ody,

    un

    ilate

    ral o

    r bi

    late

    ral i

    njec

    tion,

    incl

    usiv

    e of

    all

    imag

    ing

    guid

    ance

    cer

    vico

    thor

    acic

    22511

    lum

    bosa

    cral

    +

    22512

    each

    add

    ition

    al c

    ervi

    otho

    raci

    c or

    lum

    bosa

    cral

    ver

    tebr

    al b

    ody

    (Lis

    t se

    para

    tely

    in

    addi

    tion

    to c

    ode

    for

    prim

    ary

    proc

    edur

    e)

    22513 P

    ercu

    tane

    ous

    vert

    ebra

    l aug

    men

    tatio

    n, in

    clud

    ing

    cavi

    ty c

    reat

    ion

    (fra

    ctur

    e re

    duct

    ion

    and

    bone

    bio

    psy

    incl

    uded

    whe

    n pe

    rfor

    med

    ) us

    ing

    mec

    hani

    cal d

    evic

    e (e

    g, k

    ypho

    plas

    ty(, 1

    ver

    tebr

    al

    body

    , un

    ilate

    ral o

    r bi

    late

    ral c

    annu

    latio

    n, in

    clus

    ive

    of a

    ll im

    agin

    g gu

    idan

    ce; th

    orac

    ic

    22514

    lum

    bar

    +22515

    each

    add

    ition

    al t

    hora

    cic

    or lu

    mba

    r ve

    rteb

    ral b

    ody

    (Lis

    t se

    para

    tely

    in a

    dditi

    on t

    o co

    de f

    or p

    rimar

    y pr

    oced

    ure)

    ARTH

    RO

    DES

    IS

    27279 A

    rthr

    odes

    is, sa

    croi

    liac

    join

    t, p

    ercu

    tane

    ous

    or m

    inim

    ally

    inva

    sive

    (in

    dire

    ct v

    isua

    lizat

    ion)

    , w

    ith im

    age

    guid

    ance

    , in

    clud

    es o

    btai

    ning

    bon

    e gr

    aft

    whe

    n pe

    rfor

    med

    , an

    d pl

    acem

    ent

    of

    tran

    sfix

    ing

    devi

    ce

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    4

    Car

    diov

    ascu

    lar Sys

    tem

    PA

    CEM

    AKER

    OR IM

    PLA

    NTA

    BLE

    DEF

    IBRIL

    IATO

    R

    #33270 In

    sert

    ion

    or r

    epla

    cem

    ent

    of p

    erm

    anen

    t su

    bcut

    aneo

    us im

    plan

    tabl

    e de

    fibril

    lato

    r sy

    stem

    , w

    ith s

    ubcu

    tane

    ous

    elec

    trod

    e, in

    clud

    ing

    defib

    rilla

    tion

    thre

    shol

    d ev

    alua

    tion,

    indu

    ctio

    n of

    ar

    rhyt

    hmia

    , ev

    alua

    tion

    of s

    ensi

    ng f

    or a

    rrhy

    thm

    ia t

    erm

    inat

    ion,

    and

    pro

    gram

    min

    g or

    rep

    rogr

    amm

    ing

    of s

    ensi

    ng o

    r th

    erap

    eutic

    par

    amet

    ers,

    whe

    n pe

    rfor

    med

    .

    #33271 In

    sert

    ion

    of s

    ubcu

    tane

    ous

    impl

    anta

    ble

    defibr

    illat

    or e

    lect

    rode

    #33272 R

    emov

    al o

    f su

    bcut

    aneo

    us im

    plan

    tabl

    e de

    fibr

    illat

    or e

    lect

    rode

    #33273 R

    epos

    ition

    ing

    of p

    revi

    ousl

    y im

    plan

    ted

    subc

    utan

    eous

    impl

    anta

    ble

    defibr

    illat

    or e

    lect

    rode

    EXTRA

    CO

    RPO

    REA

    L M

    EMBRA

    NE

    OX

    YG

    ENA

    TIO

    N O

    R E

    XTRA

    CO

    RPO

    REA

    L LI

    FE

    SU

    PPO

    RT S

    ERV

    ICES

    Ex

    trac

    orpo

    real

    mem

    bran

    e ox

    ygen

    atio

    n (E

    CM

    O)/ex

    trac

    orpo

    real

    life

    sup

    port

    (EC

    LS) pr

    ovid

    ed b

    y ph

    ysic

    ian;

    initia

    tion;

    ven

    o-ve

    nous

    33947

    initi

    atio

    n, v

    eno-

    arte

    rial

    33948

    daily

    man

    agem

    ent,

    eac

    h da

    y, v

    eno-

    veno

    us

    33949

    daily

    man

    agem

    ent,

    eac

    h da

    y, v

    eno-

    arte

    rial

    33951

    inse

    rtio

    n of

    per

    iphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , pe

    rcut

    aneo

    us,

    birt

    h th

    roug

    h 5 y

    ears

    of

    age

    (incl

    udes

    flu

    oros

    copi

    c gu

    idan

    ce, w

    hen

    perf

    orm

    ed)

    33952

    inse

    rtio

    n of

    per

    iphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , pe

    rcut

    aneo

    us,

    6 y

    ears

    an

    d ol

    der

    (incl

    udes

    flu

    oros

    copi

    c gu

    idan

    ce, w

    hen

    perf

    orm

    ed)

    33953

    inse

    rtio

    n of

    per

    iphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , op

    en,

    birt

    h th

    roug

    h 5

    year

    s of

    age

    33954

    inse

    rtio

    n of

    per

    iphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , op

    en,

    6ye

    ars

    and

    olde

    r

    33955

    inse

    rtio

    n of

    cen

    tral

    can

    nula

    (e)

    by s

    tern

    otom

    y or

    tho

    raco

    tom

    y, b

    irth

    thro

    ugh

    5

    year

    s of

    age

    33956

    inse

    rtio

    n of

    cen

    tral

    can

    nula

    (e)

    by s

    tern

    otom

    y or

    tho

    raco

    tom

    y, 6

    yea

    rs a

    nd o

    lder

    33957

    repo

    sitio

    n pe

    riphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , pe

    rcut

    aneo

    us,

    birt

    h th

    roug

    h 5 y

    ears

    of

    age

    (incl

    udes

    flu

    oros

    copi

    c gu

    idan

    ce, w

    hen

    perf

    orm

    ed)

    33958

    repo

    sitio

    n pe

    riphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , pe

    rcut

    aneo

    us,

    6 y

    ears

    an

    d ol

    der

    (incl

    udes

    flu

    oros

    copi

    c gu

    idan

    ce, w

    hen

    perf

    orm

    ed)

    33959

    repo

    sitio

    n pe

    riphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , op

    en,

    birt

    h th

    roug

    h 5

    year

    s of

    age

    (in

    clud

    es f

    luor

    osco

    pic

    guid

    ance

    , w

    hen

    perf

    orm

    ed)

    #33962

    repo

    sitio

    n pe

    riphe

    ral (

    arte

    rial a

    nd/o

    r ve

    nous

    ) ca

    nnul

    a(e)

    , op

    en, 6 y

    ears

    and

    old

    er

    (incl

    udes

    flu

    oros

    copi

    c gu

    idan

    ce,

    whe

    n pe

    rfor

    med

    )

    #33963

    repo

    sitio

    n of

    cen

    tral

    can

    nula

    (e)

    by s

    tern

    otom

    y or

    tho

    raco

    tom

    y, b

    irth

    thro

    ugh

    5

    year

    s of

    age

    (in

    clud

    es f

    luor

    osco

    pic

    guid

    ance

    , w

    hen

    perf

    orm

    ed)

    #33964

    repo

    sitio

    n of

    cen

    tral

    can

    nula

    (e)

    by s

    tern

    otom

    y or

    tho

    raco

    tom

    y,

    6 y

    ears

    and

    ol

    der

    (incl

    udes

    flu

    oros

    copi

    c gu

    idan

    ce,

    whe

    n pe

    rfor

    med

    )

    #33965

    rem

    oval

    of

    perip

    hera

    l (ar

    tria

    l and

    /or

    veno

    us)

    cann

    ula(

    e),

    perc

    utan

    eous

    , bi

    rth

    thro

    ugh

    5 y

    ears

    of

    age

    #33966

    rem

    oval

    of

    perip

    hera

    l (ar

    tria

    l and

    /or

    veno

    us)

    cann

    ula(

    e),

    perc

    utan

    eous

    , 6 y

    ears

    an

    d ol

    der

  • CP

    T

    CO

    DI

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    U

    PD

    AT

    ES

    2

    01

    5

    5

    #33969

    rem

    oval

    of

    perip

    hera

    l (ar

    teria

    l and

    /or

    veno

    us)

    cann

    ula(

    e),

    open

    , bi

    rth

    thro

    ugh

    5

    year

    s of

    age

    #33984

    rem

    oval

    of

    perip

    hera

    l (ar

    teria

    l and

    /or

    veno

    us)

    cann

    ula(

    e),

    open

    , 6 y

    ears

    and

    old

    er

    #33985

    rem

    oval

    of

    cent

    ral c

    annu

    la(e

    ) by

    ste

    rnot

    omy

    or t

    hora

    coto

    me,

    birt

    h th

    roug

    h 5

    year

    s of

    age

    #33986

    rem

    oval

    of

    cent

    ral c

    annu

    la(e

    ) by

    ste

    rnot

    omy

    or t

    hora

    coto

    my,

    6 y

    ears

    and

    old

    er

    #+

    33987 A

    rter

    ial e

    xpos

    ure

    with

    cre

    atio

    n of

    gra

    ft c

    ondu

    it (e

    g, c

    him

    ney

    graf

    t) t

    o fa

    cilit

    ate

    arte

    rial

    perf

    usio

    n fo

    r EC

    MO

    /EC

    LS (Li

    st s

    epar

    atel

    y in

    add

    ition

    to

    code

    for

    prim

    ary

    proc

    edur

    e)

    #33988 In

    sert

    ion

    of le

    ft h

    eart

    ven

    t by

    tho

    raci

    c in

    cisi

    on (eg

    , st

    erno

    tom

    y, t

    hora

    coto

    my)

    for

    EC

    MO

    /EC

    LS

    #33989 R

    emov

    al o

    f le

    ft h

    eart

    ven

    t by

    tho

    raci

    c in

    cisi

    on (eg

    , st

    erno

    tom

    y, t

    hora

    coto

    my)

    for

    EC

    MO

    /EC

    LS

  • CP

    T

    CO

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    2

    01

    5

    6

    Dig

    estiv

    e Sys

    tem

    EN

    DO

    SC

    OPY

    , STO

    MA

    4438

    0 Ile

    osco

    py, t

    hrou

    gh s

    tom

    a; d

    iagn

    ostic

    , inc

    ludi

    ng c

    olie

    ctio

    n of

    spe

    cim

    en(s

    ) by

    brus

    hing

    or

    was

    hing

    , whe

    n pe

    rfor

    med

    (se

    para

    te P

    roce

    dure

    #44

    381

    w

    ith tra

    nsen

    dosc

    opic

    bal

    loon

    dila

    tion

    #44

    401

    Col

    onos

    copy

    thr

    ough

    sto

    ma;

    with

    abl

    atio

    n of

    tum

    or(s

    ), p

    olyp

    (s), o

    r ot

    her le

    sion

    (s)

    (incl

    udes

    pre

    -and

    pos

    t-di

    latio

    n an

    d gu

    ide

    wire

    pas

    sage

    , w

    hen

    perf

    orm

    ed)

    4440

    2 w

    ith e

    ndos

    copi

    c st

    ent p

    lace

    men

    t (in

    clud

    ing

    pre-

    and

    post

    -dila

    tion

    and

    guid

    e w

    ire

    pass

    age,

    whe

    n pe

    rfor

    med

    )

    4440

    3 w

    ith e

    ndos

    copi

    c, m

    ucos

    al res

    ectio

    n

    4440

    4 w

    ith d

    irect

    ed s

    ubm

    ucos

    al in

    ject

    ion(

    s), an

    y su

    bsta

    nce

    4440

    5 w

    ith tra

    nsen

    dosc

    opic

    bal

    loon

    dila

    tion

    4440

    6 w

    ith e

    ndos

    copi

    c ul

    tras

    ound

    exa

    min

    atio

    n, lim

    ited

    to t

    he s

    igm

    oid,

    des

    cend

    ing,

    tr

    ansv

    erse

    , or

    asc

    endi

    ng c

    olon

    and

    cec

    um a

    nd a

    djac

    ent st

    ruct

    ures

    4440

    7 w

    ith t

    rans

    endo

    scop

    ic u

    ltras

    ound

    gui

    ded

    intr

    amur

    al o

    r tr

    ansm

    ural

    fin

    e ne

    edle

    as

    pira

    tion/

    biop

    sy(s

    ), in

    clud

    es en

    dosc

    opic

    ul

    tras

    ound

    ex

    amin

    atio

    n lim

    ited

    to th

    e si

    gmoi

    d,

    desc

    endi

    ng, tr

    ansv

    erse

    , or as

    cend

    ing

    colo

    n an

    d ce

    cum

    and

    adj

    acen

    t st

    ruct

    ures

    4440

    8 w

    ith de

    com

    pres

    sion

    (for

    pa

    thol

    ogic

    di

    sten

    tion)

    (e

    g, vo

    lvul

    us,

    meg

    acol

    on),

    incl

    udin

    g pl

    acem

    ent of

    dec

    ompr

    essi

    on tub

    e, w

    hen

    perf

    orm

    ed

  • CP

    T

    CO

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    U

    PD

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    ES

    2

    01

    5

    7

    #

    45346 S

    igm

    oido

    scop

    y, f

    lexi

    ble;

    with

    abl

    atio

    n of

    tum

    or(s

    ), p

    olyp

    (s),

    or

    othe

    r le

    sion

    (s)

    (incl

    udes

    pre

    -and

    pos

    t-di

    latio

    n an

    d gu

    ide

    wire

    pas

    sage

    , w

    hen

    perf

    orm

    ed)

    45347

    with

    pla

    cem

    ent

    of e

    ndos

    copi

    c st

    ent

    (incl

    udes

    pre

    - an

    d po

    st-

    dila

    tion

    and

    guid

    e w

    ire p

    assa

    ge,

    whe

    n pe

    rfor

    med

    )

    45349

    with

    end

    osco

    pic

    muc

    osal

    res

    ectio

    n

    45350

    with

    ban

    d lig

    atio

    n(s)

    (eg

    , he

    mor

    rhoi

    ds)

    45388

    Col

    onos

    copy

    , fle

    xibl

    e; w

    ith a

    blat

    ion

    of t

    umor

    (s),

    pol

    yp(s

    ), o

    r ot

    her

    lesi

    on(s

    ) (in

    clud

    es p

    re-a

    nd p

    ost-

    dila

    tion

    and

    guid

    e w

    ire p

    assa

    ge,

    whe

    n pe

    rfor

    med

    )

    45389

    with

    end

    osco

    pic

    sten

    t pl

    acem

    ent

    (incl

    udes

    pre

    -and

    pos

    t-di

    latio

    n an

    d gu

    ide

    wire

    pas

    sage

    , w

    hen

    perf

    orm

    ed)

    #

    45390

    w

    ith e

    ndos

    copi

    c m

    ucos

    al r

    esec

    tion

    45393

    with

    dec

    ompr

    essi

    on (

    for

    path

    olog

    ic d

    iste

    ntio

    n) (

    eg,

    volv

    ulus

    , m

    egac

    olon

    ),

    incl

    udin

    g pl

    acem

    ent

    of d

    ecom

    pres

    sion

    tub

    e, w

    hen

    perf

    orm

    ed

    #

    45398

    w

    ith b

    and

    ligat

    ion(

    s) (

    eg,

    hem

    orrh

    oids

    )

    LAPA

    RO

    SC

    OPY

    #

    45399 U

    nlis

    ted

    proc

    edur

    e, c

    olon

    AN

    US

    46601 A

    nosc

    opy;

    dia

    gnos

    tic, w

    ith h

    igh

    reso

    lutio

    n m

    agni

    ficat

    ion

    (HRA

    0 (eg

    , co

    lpos

    cope

    , op

    erat

    ing

    mic

    rosc

    ope)

    and

    che

    mic

    al a

    gent

    enh

    ance

    men

    t, in

    clud

    ing

    colle

    ctio

    n of

    spe

    cim

    en(s

    ) by

    br

    ushi

    ng o

    r w

    ashi

    ng, w

    hen

    perf

    orm

    ed

    46607 w

    ith h

    igh-

    reso

    lutio

    n m

    agni

    ficat

    ion

    (HRA

    ) (e

    g, c

    olpo

    scop

    e, o

    pera

    ting

    mic

    rosc

    ope)

    and

    ch

    emic

    al a

    gent

    enh

    ance

    men

    t, w

    ith b

    iops

    y, s

    ingl

    e or

    mul

    tiple

    LIV

    ER/O

    TH

    ER P

    RO

    CED

    URES

    47383 A

    blat

    ion,

    1 o

    r m

    ore

    liver

    tum

    or(s

    ), p

    ercu

    tane

    ous,

    cry

    oabl

    atio

    n

    Decisio

    n to 

    unde

    rgo 

    Colono

    scop

    y

    Diagno

    stic 

    Proced

    ure

    Does Not Reach 

    Splenic Flexure

    Flexible 

    Sigm

    oido

    scop

    y (45330)

    Beyond

     Splen

    ic 

    Flexure, But Not 

    To th

    e Ce

    cum

    Colono

    scop

    y (45378; 

    Mod

    ifier 53)

    To Cecum

    Colono

    scop

    y (45378, N

    o Mod

    ifier)

    Therapeu

    tic 

    Proced

    ure

    Does Not Reach 

    Splenic Flexure

    Flexible 

    Sigm

    oido

    scop

    y (45331

    ‐45347)

    Beyond

     Splen

    ic 

    Flexure, But Not 

    To th

    e Ce

    cum

    Colono

    scop

    y (45379

    ‐45398; 

    Mod

    ifier 52)

    To Cecum

    Colono

    scop

    y (45379

    ‐45398; 

    No Mod

    ifier)

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    8

    Urin

    ary

    Sys

    tem

    V

    ESIC

    AL

    NEC

    K A

    ND

    PRO

    STA

    TE

    52441 C

    ysto

    uret

    hosc

    opy,

    with

    inse

    rtio

    n of

    per

    man

    ent

    adju

    stab

    le t

    rans

    pros

    tatic

    impl

    ant;

    si

    ngle

    impl

    ant

    +52442

    each

    add

    ition

    al p

    erm

    anen

    t ad

    just

    able

    tra

    nspr

    osta

    tic im

    plan

    t (L

    ist

    sepa

    rate

    ly in

    add

    ition

    to

    code

    for

    prim

    ary

    proc

    edur

    e)

    Ner

    vous

    Sys

    tem

    IN

    JEC

    TIO

    N, D

    RA

    INA

    GE,

    OR A

    SPI

    RA

    TIO

    N

    62302 M

    yelo

    grap

    hy v

    ia lu

    mba

    r in

    ject

    ion,

    incl

    udin

    g ra

    diol

    ogic

    al s

    uper

    visi

    on a

    nd

    inte

    rpre

    tatio

    n; c

    ervi

    cal

    62302

    thor

    acic

    62304

    lum

    bosa

    cral

    62305

    2 o

    r m

    ore

    regi

    ons

    (eg,

    lum

    bar/

    lhor

    acic

    , ce

    rvic

    al/t

    hora

    cic,

    lum

    bar/

    cerv

    ical

    , lu

    mba

    r/th

    orac

    ic/c

    ervi

    cal)

    INTRO

    DU

    CTIO

    N/IN

    JEC

    TIO

    N O

    F A

    NES

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    ETIC

    AG

    ENT (N

    ERV

    E BLO

    CK

    ),

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    GN

    OSTIC

    OR T

    HER

    APE

    UTIC

    64486 T

    rans

    veru

    s ab

    dom

    inis

    pla

    ne (

    TA

    P) b

    lock

    (ab

    dom

    inal

    pla

    ne b

    lock

    , re

    ctus

    she

    ath

    bloc

    k) u

    nila

    tera

    l by

    inje

    ctio

    n(s)

    i(in

    clud

    es im

    agin

    g gu

    idan

    ce,

    whe

    n pe

    rfor

    med

    )

    64487 b

    y co

    ntin

    uous

    infu

    sion

    (s)

    (incl

    udes

    imag

    ing

    guid

    ance

    whe

    n pe

    rfor

    med

    )

    64488 T

    rans

    vers

    us a

    bdom

    inis

    pla

    ne (

    TA

    P) b

    lock

    (ab

    dom

    inal

    pla

    ne b

    lock

    , re

    ctus

    she

    ath

    bloc

    k) b

    ilate

    ral,

    by in

    ject

    ions

    (in

    clud

    es im

    agin

    g gu

    idan

    ce, w

    hen

    perf

    orm

    ed)

    64489 b

    y co

    ntin

    uous

    infu

    sion

    s (in

    clud

    es im

    agin

    g gu

    idan

    ce,

    whe

    n pe

    rfor

    med

    )

    Eye

    and

    Ocu

    lar A

    ndex

    a

    AQ

    UEO

    US S

    HU

    NT

    66179 A

    queo

    us s

    hunt

    to

    extr

    aocu

    lar

    equa

    toria

    l pla

    te r

    eser

    voir,

    ext

    erna

    l app

    roac

    h;

    with

    out

    graf

    t

    66185

    with

    gra

    ft

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

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    2

    01

    5

    9

    Rad

    iolo

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    Ultr

    asou

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    CH

    EST

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    ltras

    ound

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    ilate

    ral,r

    eal t

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    with

    imag

    e do

    cum

    enta

    tion,

    incl

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    rfor

    med

    ; co

    mpl

    ete

    76642

    limite

    d

    BREA

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    MM

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    77061 D

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    tera

    l

    77062

    bila

    tera

    l

    +

    77063 S

    cree

    ning

    dig

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    reas

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    esis

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    late

    ral (

    List

    sep

    arat

    ely

    in a

    dditi

    on t

    o co

    de f

    or p

    rimar

    y pr

    oced

    ure)

    (U

    se 7

    7063 in

    con

    junc

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    with

    77057)

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    #77385 In

    tens

    ity m

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    rad

    iatio

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    deliv

    ery

    (IMRT),

    incl

    udes

    gui

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    d tr

    acki

    ng,

    whe

    n pe

    rfor

    med

    ; si

    mpl

    e

    #77386

    com

    plex

    #77387 G

    uida

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    loca

    lizat

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    t vo

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    med

    BO

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    JOIN

    T S

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    S

    #770

    85 D

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    y X

    -ray

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    orpt

    iom

    etry

    (D

    XA

    ), b

    one

    dens

    ity s

    tudy

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    r m

    ore

    site

    s; a

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    skel

    eton

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    , pe

    lvis

    , sp

    ine)

    , in

    clud

    ing

    vert

    ebra

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    sess

    men

    t

    #770

    86 V

    erte

    bral

    fra

    ctur

    e as

    sess

    men

    t vi

    a du

    al-e

    nerg

    y X

    -ray

    abs

    orpt

    iom

    etry

    (D

    XA

    )

    MED

    ICA

    L RA

    DIA

    TIO

    N P

    HY

    SIC

    S, D

    OSIM

    ETRY

    , TREA

    TM

    ENT D

    EVIC

    ES,

    AN

    D

    SPE

    CIA

    L SER

    VIC

    ES

    7730

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    leth

    erap

    y is

    odos

    e pl

    an; si

    mpl

    e (1

    or

    2 un

    mod

    ified

    por

    ts d

    irect

    ed t

    o a

    sing

    le a

    rea

    of

    inte

    rest

    ,) in

    clud

    es b

    asic

    dos

    imet

    ry c

    alcu

    latio

    n(s)

    7730

    7

    com

    plex

    (m

    ultip

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    eatm

    ent

    area

    s, ta

    ngen

    tial

    prot

    s, th

    e us

    e of

    w

    edge

    s,

    bloc

    king

    , ro

    tatio

    nal

    beam

    , or

    sp

    ecil

    beam

    co

    nsid

    erat

    ions

    ).

    Incl

    udes

    ba

    sic

    dosi

    met

    ry

    calc

    ulat

    ion(

    s)

    7731

    6 Br

    achy

    ther

    apy

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    plan

    ; sim

    ple

    (cal

    cula

    tion(

    s) m

    ade

    from

    1 to

    4 s

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    r rem

    ote

    afte

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    brad

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    rapy

    , 1

    chan

    nel),

    incl

    udes

    bas

    ic d

    osim

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    cal

    cula

    tion(

    s)

    7731

    7

    inte

    rmed

    iate

    (ca

    lcul

    atio

    n(s)

    mad

    e fr

    om 5

    to 1

    0 so

    urce

    s, o

    r rem

    ote

    afte

    rload

    ing

    brac

    hyth

    erap

    y, 2

    -*12

    cha

    nnel

    (s), in

    clud

    es b

    asic

    dos

    imet

    ry c

    alcu

    latio

    n(s)

    7731

    8

    com

    plex

    (ca

    lcul

    atio

    n(s)

    mad

    e fr

    om o

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    ourc

    es o

    r re

    mot

    e af

    terlo

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    achy

    ther

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    ove

    r 12

    cha

    nnel

    (s) in

    clud

    es b

    asic

    dos

    imet

    ry c

    alcu

    latio

    n(s)

  • CP

    T

    CO

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    NG

    U

    PD

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    Path

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    PR

    ESU

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    DRU

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    #80300 D

    rug

    scre

    en ,

    any

    num

    ber

    of d

    rug

    clas

    ses

    from

    Dru

    g C

    lass

    Lis

    t A

    ; an

    y nu

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    non

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    dev

    ices

    or

    proc

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    (eg

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    unoa

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    n, in

    clud

    ing

    inst

    rum

    ente

    d-as

    sist

    ed w

    hen

    perf

    orm

    ed (

    eg,

    dips

    ticks

    , cu

    ps,

    card

    s, c

    artr

    idge

    s),

    per

    date

    of

    serv

    ice

    #80301

    sing

    le d

    rug

    clas

    s m

    etho

    d, b

    y in

    stru

    men

    ted

    test

    sys

    tem

    s (e

    g, d

    iscr

    ete

    mul

    ticha

    nnel

    che

    mis

    try

    anal

    yzer

    s ut

    ilizi

    ng im

    mun

    oass

    ay o

    r en

    zym

    e as

    say)

    , pe

    r da

    te o

    f se

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    e

    # 8

    0302 D

    rug

    scre

    en,

    pres

    umpt

    ive,

    sin

    gle

    drug

    cla

    ss f

    rom

    Dru

    g C

    lass

    Lis

    t B,

    by

    imm

    unoa

    ssay

    (eg

    , EL

    ISA

    ) or

    non

    -TLC

    chr

    omat

    ogra

    phy

    with

    out

    mas

    s sp

    ectr

    omet

    ry (

    eg,

    GC

    , H

    PLC

    ), e

    ach

    proc

    edur

    e

    #80303 D

    rug

    scre

    en,

    any

    num

    ber

    of d

    rug

    clas

    ses,

    pre

    sum

    ptiv

    e, s

    ingl

    e or

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    tiple

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    g cl

    ass

    met

    hod;

    thi

    n la

    yer

    chro

    mat

    ogra

    phy

    proc

    edur

    e(s)

    (TLC

    ) (e

    gm a

    cid,

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    , al

    kalo

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    plat

    e),

    per

    date

    of

    serv

    ice

    #80304

    not

    othe

    rwis

    e sp

    ecifi

    ed p

    resu

    mpt

    ive

    proc

    edur

    e (d

    g, T

    OF,

    MA

    LDI,

    LDTD

    , D

    ESI,

    DA

    RT),

    eac

    h pr

    oced

    ure

    DEF

    INIT

    IVE

    DRU

    G T

    ESTIN

    G

    #80320 A

    lcoh

    ols

    #80321 A

    lcoh

    ol b

    iom

    arke

    rs;

    1 o

    r 2

    #80322

    3 o

    r m

    ore

    #80323 A

    lkal

    oids

    , no

    t ot

    herw

    ise

    spec

    ified

    #80324 A

    mph

    etam

    ines

    ; 1 o

    r 2

    #80325

    3 o

    r 4

    #80326

    5 o

    r m

    ore

    #80327 A

    nabo

    lic s

    tero

    ids;

    1 o

    r 2

    #80328

    3 o

    r m

    ore

    #80329 A

    nage

    sics

    , no

    n-op

    iod;

    1 o

    r 2

    #80330

    3-5

    #80331

    6 o

    r m

    ore

    #80332 A

    ntid

    epre

    ssan

    ts,

    sero

    tone

    rgic

    cla

    ss;

    1 o

    r 2

    #80333

    3-5

    #80334

    6 o

    r m

    ore

    #80335 A

    ntid

    epre

    ssan

    ts,

    tric

    yclic

    and

    oth

    er c

    yclic

    als;

    1 o

    r 2

    #80336

    3-5

    #80337

    6 o

    r m

    ore

    #80338 A

    ntid

    epre

    ssan

    ts,

    not

    othe

    rwis

    e sp

    ecifi

    ed

    #80339 A

    ntie

    pile

    ptic

    s, n

    ot o

    ther

    wis

    e sp

    ecifi

    ed;

    1-3

    #80340

    4-6

    #80341

    7 o

    r m

    ore

    #80342 A

    ntip

    sych

    otic

    s, n

    ot o

    ther

    wis

    e sp

    ecifi

    ed;

    1-3

    #80343

    4-6

    #80344

    7 o

    r m

    ore

    #80345 B

    arbi

    tura

    tes

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    11

    #80346 B

    enzo

    diaz

    epin

    es;

    1-1

    2

    #80347

    13 o

    r m

    ore

    #80348 B

    upre

    norp

    hine

    #80349 C

    anna

    bino

    ids,

    syn

    thet

    ic,

    1-3

    #80350 C

    anna

    bino

    ids,

    syn

    thet

    ic;

    1-3

    #80351

    4-6

    #80352

    7 o

    r m

    ore

    #80353 C

    ocai

    ne

    #80354 F

    enta

    nyl

    #80355 G

    abap

    entin

    , no

    n-bl

    ood

    #80356 H

    eroi

    n m

    etab

    olite

    #80357 K

    etam

    ine

    and

    nork

    etam

    ine

    #80358 M

    etha

    done

    #80359 M

    ethy

    lene

    diox

    yam

    phet

    amin

    es (

    MD

    A,

    MD

    EA,

    MD

    MA

    )

    #80360 M

    ethy

    lphe

    nida

    te

    #80361 O

    piat

    es,

    1 o

    r M

    ore

    #80362 O

    piod

    s an

    d op

    iate

    ana

    logs

    , 1 o

    r 2

    #80363

    3 o

    r 4

    #80364

    5 o

    r m

    ore

    #80365 O

    xyco

    done

    #80366 P

    rega

    balin

    #80367 P

    ropo

    xyph

    ene

    #80368 S

    edat

    ive

    hypn

    otic

    s (n

    on-b

    enzo

    diaz

    epin

    es)

    #80369 S

    kele

    tal m

    uscl

    e re

    laxa

    nts;

    1 o

    r 2

    #80370

    3 o

    r m

    ore

    #80371 S

    timul

    ants

    , sy

    nthe

    tic

    #80372 T

    apen

    tado

    l

    #80373 T

    ram

    adol

    #80374 S

    tere

    oiso

    mer

    (en

    antio

    mer

    ) an

    alys

    is,

    sing

    le d

    rug

    clas

    s

    #80375 D

    rug(

    s) o

    r su

    bsta

    nce(

    s),

    defin

    itive

    , qu

    alita

    tive

    or q

    uant

    itive

    , no

    t ot

    herw

    ise

    spec

    ified

    ; 1-3

    #80376

    4-6

    #80377

    7 o

    r m

    ore

    TH

    ERA

    PEU

    TIC

    DRU

    G A

    SSA

    YS

    80163 D

    igox

    in;

    free

    #80165 V

    alpr

    oic

    acid

    (di

    prop

    ylac

    etic

    aci

    d);

    free

    MO

    LEC

    ULA

    R P

    ATH

    OLO

    GY

    81246 F

    LT3 (

    fms-

    rela

    ted

    tyro

    sine

    kin

    ase

    3)

    (eg,

    acu

    te m

    yelo

    id le

    ukem

    ia),

    gen

    e an

    alys

    is;

    tyro

    sine

    kin

    ase

    dom

    ain

    (TK

    D)

    varia

    nts

    (eg,

    D835,

    I836)

    #81288 M

    LH1 (

    mut

    L ho

    mal

    og 1

    , co

    lon

    canc

    er,

    nonp

    olyp

    osis

    typ

    e 2)

    (eg,

    her

    edita

    ry

    non-

    poly

    posi

    s co

    lore

    ctal

    can

    cer,

    Lyn

    ch s

    yndr

    ome)

    gen

    e an

    alys

    is;

    prom

    oter

    met

    hyla

    tion

    anal

    ysis

    81313 P

    CA

    3/K

    LK3 (

    pros

    tate

    can

    cer

    antig

    en 3

    [no

    n-pr

    otei

    n co

    ding

    ]/ka

    llikr

    ein-

    rela

    ted

    pept

    ides

    3 [

    pros

    tate

    spe

    cific

    ant

    igen

    ]) r

    atio

    (eg

    , pr

    osta

    te c

    ance

    r)

  • CP

    T

    CO

    DI

    NG

    U

    PD

    AT

    ES

    2

    01

    5

    12

    GEN

    OM

    IC S

    EQU

    ENC

    ING

    PRO

    CED

    URES

    AN

    D O

    TH

    ER M

    OLE

    CU

    LAR M

    ULT

    IAN

    ALY

    TE

    ASSA

    YS

    81410 A

    ortic

    dys

    func

    tion

    or d

    ilatio

    n (e

    g, M

    arfa

    n sy

    ndro

    me,

    Loe

    ys D

    ietz

    syn

    drom

    e,

    Ehle

    r D

    anlo

    s sy

    ndro

    me

    type

    IV,

    arte

    rial t

    ortu

    osity

    syn

    drom

    e);

    geno

    mic

    seq

    uenc

    e an

    alys

    is p

    anes

    , m

    ust

    incl

    ude

    sequ

    enci

    ng o

    f at

    leas

    t 9 g

    enes

    , in

    clud

    ing

    FBN

    1,

    TG

    FBR1,

    TG

    FBR2,

    CO

    L3A

    1,

    MY

    H1,

    AC

    TA

    2,

    SLC

    2A

    10,

    SM

    AD

    3,

    and

    MY

    LK

    81411

    du

    plic

    atio

    n/de

    letio

    n an

    alys

    is p

    anel

    , m

    ust

    incl

    ude

    anal

    yses

    for

    TG

    FBR1,

    TG

    FBR2,

    MY

    H11,

    and

    CO

    L3A

    1

    81415 E

    xom

    e (e

    g, u

    nexp

    lain

    ed c

    onst

    itutio

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    r he

    ritab

    le d

    isor

    der

    or s

    yndr

    ome0

    ; se

    quen

    ce a

    naly

    sis

    +81416

    sequ

    ence

    ana

    lysi

    s, e

    ach

    com

    para

    tor

    exom

    e (e

    g, p

    aren

    ts,

    sibl

    ings

    ) (li

    st

    sepa

    rate

    ly in

    add

    ition

    to

    code

    for

    prim

    ary

    proc

    edur

    e)

    81417

    re-e

    valu

    atio

    n of

    pre

    viou

    sly

    obta

    ined

    exo

    me

    sequ

    ence

    (eg

    , up

    date

    d kn

    owle

    dge

    or u

    nrel

    ated

    con

    ditio

    n/sy

    ndro

    me)