2240-rupinder-tewari

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1. BRIEF PROFILE

Name : Rupinder TewariAddress: Professor and Coordinator,Centre for Microbial Biotechnology,Panjab University,Chandigarh 160014Email: [email protected]

Ph. No.+91-9872216184

D.O.B/sex: Sept. 27, 1956; male

Fields of specialization: Microbiology andMicrobial Biotechnology

B.Sc (Hons. School), M.Sc (Hons. School), Deptt. of Microbiology, Panjab University,

Chandigarh.

Ph.D(Microbiology), Panjab University, Chandigarh.

Ph.D. (Microbiology), University of London, London, U.K.

Post Doctorate Fellow,Washington University, St. Louis, MO, USA.

Recipient of :

(i) Rockefeller Biotechnology Fellowship awarded by The Rockefeller

Foundation, USA.

(ii) Commonwealth Academic Staff Scholarshipawarded by The British Council,

U.K.

Fellow,Panjab University Senate (2008 onwards),

Dean (Faculty of Sciences) (2012 onwards)

Founder,Centre for Microbial Biotechnology, PU, Chd. (2008)

Chief-Mentor, Centre for Innovation Cluster in Biotechnology (CIC-B) (2014

onwards) Funded by BIRAC-NInC (GOI, New Delhi)

Coordinator, DST-Policy Research Centre on Promotion of Industry-Academia

interactions. (2013 onwards)

Coordinator,Chandigarh Innovation & Knowledge Cluster (CRIKC) (2013 onwards)

Formerly Director (Hony.), Centre for Industry-Institute Partnership programme

(CIIPP) of PU, Chd. (2012-13).


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Formerly, Chairman, Deptt. of Biotechnology, Panjab University, Chandigarh.

(2004-05)

Formerly, Coordinator,UGC-SAP, Dept. of Biotechnology, PU, Chd.(2005-09)

Formerly, Coordinator, UGC-NET exams held in Dec.2008 and June, 2009.

Formerly, Coordinator, PU Ph.D Entrance exam held in 2009 & 2010

Formerly, Chairperson,UG-CET Admissions of PU in 2010 & 2013.

Granted research projects by agencies like DBT, DST, CSIR, ICMR and UGC.

Research publications in high impact journals (Acta Crystt., JBC, Infect. Immun.,

Appl. Environ. Microbiol., BioResource etc.).

Submitted many gene sequencesin GenBank

Submitted many protein structuresin Protein Data Bank (PDB).

Submitted many microbial culturesin MTCC, IMTECH (CSIR branch), Chandigarh

Published three booksin the areas of Microbiology/Biotechnology. Fourth will be out

soon.

Written two e-chapterson Industrial Microbiology (80 pages) and DNAReplication

(60 pages)for NISCAIR (CSIR, New Delhi)

Guided 24 Ph.Ds. students and more than 40 M.Sc students for their theses /

dissertations.10 research scholars pursuing Ph.D.

Organized various National/ International Conferences/Seminars/Workshops.

Chaired sessionsin National / International conferences

Delivered more than 50 invited lectures at various places including JNU (New

Delhi); IISc (Bangalore); BHU (Banares); Indian Science Congress (2014); CSIR

Regional Research Laboratory (Jammu); JALMA (Agra); Univ. of Pune, Pune; Anna

University, Chennai etc.

Member, Board of Editors of Indian Jr. of Microbiology (2009-11)

Reviewer, many journals (national and internationals)

Designed Biotechnology Policy-2004for U.T. (Chandigarh).

Founder, Chandigarh chapter, Association of Microbiologists of India (AMI)

.


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2. TEACHING & RESEARCH EXPERIENCE

-- 35 years. (UG, PG and PhD course work)

Introductory Microbiology Industrial Microbiology

Environment Microbiology Recombinant DNA Technology

Microbial Biotechnology

Bio-safety Guidelines, GLP, GMP

3. RESEARCH PROJECTS (Funded)

(i) Cloning of Penicillin G Acylase (pga) gene in 100% stable asd+vector andits expression in asd-E.coli. (1996-99). Funding agency: CSIR, New Delhi.

(ii) Biodegradation of Nitro-aromatic compounds by microbes. (2002-05).Funding Agency: DRDO, New Delhi.

(iii) Microbial consortium of Phosphate solubilizers and their genotyping.

(2003-06). Funding agency: UGC, New Delhi.

(iv) Production and purification of pectinase from a Bacillus sp.Funding Agency: UGC, New Delhi (1997-2000).

(v) Construction of illuminating bacteria for the detection of toxic compoundspresent in the water samples. (2003-05) Funding agency: DST, New Delhi.

(vi) Cloning, expression and purification of aspartate semialdehydedehydrogenase of Mycobacterium tuberculosis. Funding Agency: DBT,New Delhi (2003-06)

(vii) Cloning of chitinase gene of Enterobacter sp. NRG4 andcharacterization and applications of recombinant chitinase. (2006-09).Funding agency: DBT, New Delhi.

(viii) Characterization of antimicrobial compounds of Burkholderia gladioli.(2007-08) Funding agency: DBT, New Delhi.

(ix) Structure determination of aspartate semialdehyde dehydrogenase ofMycobacterium tuberculosis. (2008-10) Funding agency: DBT, New Delhi.


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(x) Biotechnological route for the production of N-acetyl-D-glucosamine: a

pain killer.(2011-14).Funding agency: UGC, New Delhi

(xi) Cloning, expression, purification and structure determination of MurA ofMycobcaterium tuberculosis(2011-14). Funding agency: DST, New Delhi

4. M.Sc. / Ph.D SUPERVISOR

(i) Guided over 40 M.Sc students for their dissertations(ii) Guided 24 Ph.D students ; Guiding 10 Ph.D students

5. RESEARCH PUBLICATIONS (Impact factor > 3.0)(Total research publications 78)

1. S. Walia, T. Madhavan, R. Tewari(1986). Protein patterns, serotyping & plasmidprofiles in the epidemiological finger printing of Ps. aeruginosa. Eur. J. Clin.Microbiol. & Infec. Dis. 7(2): 279-285. (IF: 3.024)

2. S. Walia, T. Madhavan, R. Tewari(1986). Plasmid profiles and klebocin types inepidemiological studies of infections by Klebsiella pneumoniae. Eur. J.Clin.Microbiol. & Infec. Dis. 7(2): 279-285. (IF: 3.024)

3. A. Khan, R. Tewari, S. Walia (1988). Molecular cloning of 3-phenylcatecholdioxygenase involved in catabolic pathway of biphenyl from Pseudomonas putidaand its expression in E.coli. Appl. Environ. Microbiol. 54: 2664-71. (IF: 3.678)

4. R. Tewari, S. Hultgren, S. Abraham (1993). Neutrophil activation by nascent

FimH subunits o Rf Type 1 fimbriae purified from the periplasm of Escherichiacoli. J.Biol. Chem.268(4): 3009-15. (IF: 4.651)

5. R. Tewari, T. Ikada, S. Abraham (1995). The PapG tip adhesin of P fimbriaeprotects E.colifrom neutrophil bactericidal activity. Infect. Immun. 62(12): 5296-5304. (IF: 4.074)

6. D.R. Kashyap, P.K. Vohra, R. Tewari (2000). Applications of Pectinases: AReview. Biores. Technol.77(3): 215-227. (IF: 4.750)

7. G. Chaturvedi, R. Tewari, N. Mrigank, N.K. Ganguly (2001). Inhibition ofHelicobacter pylori adherence by a peptide derived from neuraminyl lactosebinding adhesin. Molec. Cell. Biochem. 228: 83-89. (IF: 5.372)

8. G. Hoondal, R.P. Tiwari, R. Tewari, N. Dahiya (2002). Microbial alkalinepectinases and their industrial applications: a review. Appl. Microbiol.Biotechnol. 59: 409-418. (IF: 3.689)

9. D.R. Kashyap, S.K. Soni,R.Tewari (2003). Enhanced production of pectinaseby Bacillussp. DT7using solid-state fermentation. Biores. Technol. 88: 251-54.(IF: 4.750)


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10. N. Dahiya, R. Tewari, G.S. Hoondal (2006). Biotechnological aspects ofchitinolytic enzymes: a review. Appl. Microbiol. Biotechnol.. 71(6): 773-82. (IF:3.689)

11. V. Mittal, O. Singh, H. Nayyar, J. Kaur, R Tewari(2008). Stimulatory effect of P-solubilizing fungal strains (Aspergillusawarmoriand Penicilliumcitrinum) on the

yield of chickpea (CicerarietinumL. cv. GPF2). Soil Biol. Biochem.40: 718-727(IF: 3.654)

12. P. Rishi, S. Mavi, S. Bharhan, G. Shukla, R. Tewari(2009). Protective efficacy ofprobiotic alone or in conjugation with a prebiotic in Salmonella induced liverdamage. FEMS Microbiol. Ecol. 69(2): 222-30. (IF: 3.563)

13. A. Garg, R. Tewari, G.P.S. Raghav (2010). KiDoQ: using docking based energyscores to develop ligand-based model for predicting antibacterials. BMCBioinformatics11:125 doi:10. 1186/1471-2105-11-125. (IF: 3.02)

14. A. Garg, R. Tewari, G.P.S. Raghav (2010). Virtual Screening of Potential Druglike inhibitors of Mycobacterium tuberculosis. BMC Bioinformatics.11 (suppl.):

S53. (IF: 3.02)

15. A. Gautam, R. Vyas,R. Tewari (2010). Peptidoglycan Biosynthesis Machinery:A rich source of drug targets. Crit. Rev. Biotechnol.31 (4): 295-336. (IF: 5.095)

16. S. Khan, V. Bhakuni, V. Praveen,R.Tewari, C.K.M. Tripathi, V.D. Gupta (2010).Maximizing the native concentration and shelf life of protein: a multiobjectiveoptimization to reduce aggregation. Appl. Microbiol. Biotechnol. 89(1): 99-108.(IF: 3.689)

17. R. Vyas, R. Tewari,M, Weiss, S.Karthikeyan (2012). Crystal structures of ternarycomplexes of aspartate semialdehyde dehydrogenase (Rv3708c) fromMycobacterium tuberculosis H37Rv. Acta Crystallogr.D68, 671-679 (IF 11.2)

6. Books

R. Tewari,K.G. Mukerji, J.K. Gupta and L.K. Gupta (2001) Role of Microbes inthe Management of Environmental Pollution. A.P.H. Publishing Corporation,New Delhi. ISBN : 81-7648-223-4

Tiwari, R. P., Hoondal, G. S. and Tewari, R.(2004). Laboratory Techniques inMicrobiology and Biotechnology. Abhishek Publishers, Chandigarh . ISBN:8182470773

Tewari R (2007) Invitation to Biotechnology. Viva Publishers, New Delhi.ISBN: 81-309-0599-X

Guest Editor of a book, Microbial Biotechnology,a multi volume set on RecentDevelopments in Biotechnology. Publisher: Studium Press LLC, Houston, USA.Will be in market by end of 2014.


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7. e-Chapters for NISCAIR (CSIR, GoI)

Tewari, Rupinder(2008) Industrial Microbiology.

http://hdl.handle.net/123456789/684 Tewari, Rupinder(2008) DNA Replication. http://hdl.handle.net/123456789/685

8. Gene sequences submitted to GenBank

S. No. Accession no. Organism Gene

1. GQ906590 Escherichia coli Chitobiase (chb)

2.AY754011 Enterococcus

faeciumVancomycin resistance protein A (vanA)

3. AY751080Enterococcuscasseliflavus

Vancomycin resistance protein C2(vanC2)

4. AY372113 Mycobacteriumtuberculosis H37Rv

Aspartate semialdehyde dehydrogenase(asd)

5. GU166748Pseudomonasaeruginosa strainPAO1

Dihydrodipicolinate synthase (dapA)

6. EU840989Mycobacteriumtuberculosis H37Rv

UDP-N-acetylenolpyruvylglucosaminereductase (murB)

7. DQ013365Enterobacter sp.NRG-4

Chitinase (chiA) gene

8. AY786180Enterococcusgallinarum

Vancomycin resistance protein C1(vanC1)

9. AY786179Enterococcusgallinarum

Vancomycin resistance protein B (vanB)

9. Proteins Structures submitted to Protein Data Bank (PDB)

S. No. PDB-ID Organism EnzymeResolution

()

1. 3LLGMycobacteriumtuberculosis H37Rv

Aspartate semi-aldehyde dehydrogenase 2.18

2. 3PULAcinetobacterbaumannii

Dhydrodipicolinate synthase 2.30

3. 3PUOPseudomonasaeruginosa

Dihydrodipicolinate synthase 2.65

4. 3PUD Acinetobacterbaumannii Dhydrodipicolinate synthase 2.80

5. 3PUEAcinetobacterbaumannii

Dhydrodipicolinate synthase 2.60

6. 3PS7Pseudomonasaeruginosa


7. 3KUBMycobacteriumtuberculosis H37Rv

Aspartate semi-aldehyde dehydrogenase 2.43

8. 3NOEPseudomonasaeruginosa



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10. Bacterial strains submitted to Microbial Type Culture Collection Centre(MTCC) , IMTECH (CSIR Branch) Chandigarh

11. WORKSHOPS / CONFERENCES ATTENDED

More than 40 papers presented in National and International conferences (USA,UK, Canada)

Organized various conferences/Workshops/Seminars/Special Lectures by

National and International scientists Chaired sessions in various conferences (national & international)

S. No. Organism MTCC Accession #

1. Aspergillus awamori VQ2 8002

2. Aspergillus awamori VH1 8003

3. Penicillium citrinum VPT 8004

4. Penicillium citrinum VU1 80055. Penicillium citrinum VR250 8006

6. Penicillium citrinum VPC 8007

7. Burkholderia gladioli 10216

8. Burkholderia gladioli 10217

9. Serratia marcescens 10238

10. Enterobacter aerogenes 10208

11. Pseudomonas synxantha 10223

12. Burkholderia gladioli 1024213. Enterobacter hormaechei 10240

14. Serratia marcescens 10241


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12. INVITED LECTURES

Delivered more than 40 invited lectures at various institutes including JNU (New Delhi),IISc (Bangalore), Pune University (Pune), Anna University (Chennai), RRL (Jammu),HPU (Shimla), Punjabi University (Patiala), HAU (Hissar).

13. MEMBERSHIP of SOCIETIES

1. Association of Microbiologists of India.( AMI).-- Life Member2. All India Biotech Association (AIBA)---- Life Member3. Electron Microscope Society of India. (EMSI)---- Life Member4. Biosensor Society of India --- Life member5. Society for Promotion of Science & Technology in India --- Life Member6. Environmental Society of India.7. American Society of Microbiology (1990-97)8. Canadian Society of Microbiology (2000-02)9. Society for Promotion of Science & Technology in India

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2240-rupinder-tewari