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2010
HIV/AIDS surveillance in Europe
European Centre for Disease Prevention and Control, StockholmWHO Regional Office for Europe, Copenhagen
2
HIV/AIDS surveillance
• Describes the HIV epidemic and its characteristics, and identifies population groups at risk and in need for targeted prevention measures.
• Monitors trends in HIV/AIDS over time in order to assess the situation and compare trends across Europe.
• Improves and harmonises European HIV/AIDS surveillance methods and catalyses national efforts to improve HIV/AIDS surveillance.
• Supplies relevant data for evidence-based public health policies.
3
HIV/AIDS surveillance in EuropeFramework for data collection
ECDC
Competent Bodies for surveillance
Provides non-EU/EEA HIV national contact
point nomination
HIV contact points nominated
Data sent to the joint HIV/AIDS database hosted by ECDC
Provide EU/EEAHIV national contact
point nomination
WHO EURO = 'Competent Body' for non-EU/EEA countries
Data validation performed by ECDC
WHO/EuropeHIV experts
ECDC HIV
experts
Full access to the HIV/AIDS
validated data
HIV national contact points
WHO/Europe As from 2008, ECDC and the WHO Regional Office for Europe jointly coordinate HIV/AIDS surveillance in 54 countries.
A sustainable surveillance system is crucial when informing about prevention efforts and healthcare planning.
5
HIV infections diagnosed in 2010,WHO European Region and EU/EEA
• No data from Austria, Liechtenstein • ** Excludes individuals originating from countries with generalised epidemics.
Characteristics of cases
EU/EEA countries*
Number of HIV cases 27116Rate per 100 000 population 5.7Percentage of cases: Age 15–24 years 10.9%Female 26.3%Transmission mode Heterosexual 25%**Men who have sex with men 38%Injecting drug use 4%Unknown 15.1%
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
< 22 to < 1010 to < 20≥ 20Missing or excluded data
HIV infections diagnosed, 2010All cases, EU/EEA
Rate as number per 100 000 population
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
< 11 to < 33 to < 5≥ 5Missing or excluded data
HIV infections diagnosed, 2010Men who have sex with men, EU/EEA
Rate as number per 100 000 male population
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
< 0.20.2 to < 11 to < 3≥ 3Missing or excluded data
HIV infections diagnosed, 2010Injecting Drug Use, EU/EEA
Rate as number per 100 000 population
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
9
HIV infections diagnosed 1984–2010, EU/EEA
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
0
50000
100000
150000
200000
250000
300000
350000
400000
Cumulative totals
HIV diagnoses by year
Num
ber
of
case
s
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
10
HIV infection by transmission group and origin in EU/EEA, 2004–10
Predominant transmission group: men who have sex with men
Data were not included or not available from Austria, Estonia and Poland.
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
11
Heterosexually acquired HIV infections Proportion of cases among persons originating from countries with generalised epidemics, 2010
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
Portugal
Finland
Iceland
EU/EEA
Germany
Netherlands
Slovenia
Greece
Norway
Luxembourg
Ireland
Malta
Sweden
United Kingdom
Belgium
0 10 20 30 40 50 60 70
%
12
Conclusions
• HIV infection is of major public health importance in Europe, with evidence of continuing transmission and no clear signs of decrease.
• Large heterogeneity exists in HIV epidemics in the EU/EEA:– Predominant mode of transmission is sex between
men.– Considerable proportion among heterosexually
acquired cases comes from countries with a generalised epidemic.
– Continued HIV transmission among IDUs in eastern EU countries.
14
HIV infections diagnosed in 2010 per 100 000 population: all cases
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
15
HIV infections diagnosed in 2010 per 100 000 male population: men who have sex with men
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
16
HIV infections diagnosed in 2010 per 100 000 population: injecting drug users
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
17
HIV infections diagnosed in 2010 per 100 000 population: heterosexual cases
Excludes persons from countries with generalised epidemics.
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
19
HIV infections diagnosed in 2010 WHO European Region
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
Characteristics of cases
WHO Europea
n Region*
West* Centre* East
Number of HIV cases 118 335 25 659 2 478 90 198Rate per 100 000 population 13.7 6.6 1.3 31.7Percentage of cases Age 15–24 years** 11.6% 10.0% 17% 13%Female 38% 27% 19% 42%Transmission mode** Heterosexual 43% 24%*** 24% 48%Men who have sex with men 20% 39% 29% 0.7%Injecting drug use 23% 4% 4% 43%Unknown 13% 16% 41% 7%
*No data from the following countries: Austria, Liechtenstein, Monaco.** Countries with no data on age or transmission mode excluded.*** Excludes individuals originating from countries with generalised epidemics.
20
HIV infections 1984–2010, WHO European Region
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
0
100000
200000
300000
400000
500000
600000
700000
cumulative totals
HIV diagnoses by year
Num
ber
of
case
s
HIV infection in the three geographical areas and EU/EEA, WHO European Region, 2004–10
Data not reported or not available from Austria, Russia, Monaco.
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
2004 2005 2006 2007 2008 2009 20100
5
10
15
20
WestWest adjustedEU/EEAEU/EEA adjustedCentreEast
Case
s per
100 0
00 p
opula
tion
22
HIV infections, 2004–10: transmission groups in WHO European Region, East
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
2004 2005 2006 2007 2008 2009 20100
2000
4000
6000
8000
10000
12000
14000
IDUHeterosexual Men who have sex with menMother-to-child-transmission Other/undeterminedN
um
ber
of
case
s
HIV infections, 2004–09: transmission groups in WHO European Region, Centre
23Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
2004 2005 2006 2007 2008 2009 20100
100
200
300
400
500
600
700
Injecting drug usersHeterosexual casesMen who have sex with menMather-to-child-transmission-casesOthers
Num
ber
of
case
s
24
2004 2005 2006 2007 2008 2009 20100
0.5
1
1.5
2
2.5
West*EU/EEACentreEast**
Case
s per
100 0
00 p
opula
tion
AIDS diagnoses, 2004–10WHO European Region
Source: ECDC/WHO. HIV/AIDS Surveillance in Europe, 2010
Countries that have consistently reported AIDS since 2004 included: West Austria, Belgium, Finland, France, Germany, Greece, Iceland, Ireland, Israel, Italy, Luxembourg, Malta, Netherlands, Norway, Portugal, Spain, San Marino, Switzerland, United Kingdom; Centre: Albania, Bosnia and Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, the former Yugoslav Republic of Macedonia, Hungary, Montenegro, Poland, Romania, Serbia, Slovakia, Slovenia; East: Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kyrgyzstan, Latvia, Lithuania, Moldova, Tajikistan, Turkmenistan, Uzbekistan.
25
Distribution of three most common AIDS indicative diseases by transmission group, WHO European Region, 2010
Candidiasis, oesophageal
Mycobacterium tuberculosis*
Pneumocystis pneumonia
Wasting syndrome due to HIV
Candidiasis, oesophageal
Mycobacterium tuberculosis*
Candidiasis, oesophageal
Kaposis sarcoma
Pneumocystis pneumonia
Hete
roID
UM
SM
0 100 200 300 400 500 600 700 800
Number of cases
*pulmonary in adults and adolescents
26
Limitations of data
• Coverage:– Data from a number of countries is not reported to
TESSy and for several others reported at sub-national level.
• Reporting and testing:– Reporting systems may differ across countries; – Testing patterns may have changed over time.
• Data quality – Completeness is insufficient for several variables;– Under-reporting, reporting delays influence
interpretation of recent trends.
27
Conclusions (1)
• HIV infection is a disease of major public health importance in Europe, with evidence of continuing HIV transmission in European countries.
• Overall, the number of diagnosed cases of HIV infection has shown no clear sign of decrease, while AIDS diagnoses continue to decline in the WHO European Region, except in several Eastern and Central European countries.
28
Conclusions (2)
Heterosexual transmission:• increasing in many countries in the East; • in the West, a considerable proportion are individuals
originating from countries with generalised epidemic.
Transmission among injecting drug users: • continuing transmission in many countries in the East;• low-level epidemic in the West and Centre.
Transmission among men who have sex with men:• increasing and predominant epidemic in many countries in the
West;• increasing transmission in Central Europe.