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NanoMet3 First PEMSPN Instrument Presented by Andreas Knecht

140712-VERT Tel Aviv - Technion · 2014. 12. 14. · 100 120 12 0 20 40 60 100 80 [% of cells] w ithou par cles w ith par cles 1 controlµm + cytochalasin D F-Actin 78-nm particles

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  • NanoMet3  First  PEMS-‐PN  Instrument  Presented  by  Andreas  Knecht

  • Contents

    Introduction

    Motivation

    Measuring and technical requirements

    NanoMet3 technology

    Features and specifications

    Validation and performance

    Summary and outlook

  • 1995 nothing than nano-particlesSince

  • Heavy duty Machinery.

    Nano-partticle emission control for safety

    Matter is a spin-off the ETH & Swiss government particle counting project

    Tunnels in the Swiss alps alone1000

  • Contents

    Introduction

    Motivation

    Measuring and technical requirements

    NanoMet3 technology

    Features and specifications

    Validation and performance

    Summary and outlook

  • Why are Nano Particle dangerous

  • Small & Insoluble = Health Hazard

    F-Actin 1-!m particles

    control + cyt. D0

    20

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    100

    120

    1 20

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    [% o

    f ce

    lls] without particles

    with particles

    control + cytochalasin D1 µm

    F-Actin 78-nm particles (neutral)

    0

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    1 2control + cyt. D0

    20

    40

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    100

    80

    [% o

    f ce

    lls] without particles

    with particles

    control + cytochalasin D0.078 µm

    F-Actin 78-nm particles (neutral)

    0

    10

    20

    30

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    60

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    1 2control + cyt. D0

    20

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    [% o

    f ce

    lls] without particles

    with particles

    control + cytochalasin D0.078 µm

    Human Cell Exposed Micro and Nano Particles

  • 100nm 800nm

    Par?cle  mass

    Particle Mass

  • 100nm 800nm

    Par?cle  number

    Particle Number

  • Particle MassParticle Number

    Most Hazardous Polluant

  • 2017  European  Commission’s  PEMS-‐PN  approach

    PMP  Measurement

    MaAer  Aerosol  NanoMet3

           Real  Driving  Emissions

  • Contents

    Introduction

    Motivation

    Measuring and technical requirements

    NanoMet3 technology

    Features and specifications

    Validation and performance

    Summary and outlook

  • NanoMet3  Technology

  • exhaust with nano-droplets

    Dilution

    droplets remain despite hot dilution

    dilution air (pre-heated)

    sample with nano-droplets

  • Par@cle  Coun@ng:  Diffusion  Size  Classifier

  • What do we measure?

  • 1fA=0.000000000000001A

  • Contents

    Introduction

    Motivation

    Measuring and technical requirements

    NanoMet3 technology

    Features and specifications

    Validation and performance

    Summary and outlook

  • NanoMet3

    Ø Particle number concentration [#/cm3] or [#/s] with flow meter  

    Ø Average particle diameter [nm]  

    Ø Calculated particle mass [mg/m3]  

    Ø Lung deposition surface area [µm2/cm3]

    Measuring  Data

  • On Road Particle Counting

  • Cabine Counting

  • Contents

    Introduction

    Motivation

    Measuring and technical requirements

    NanoMet3 technology

    Features and specifications

    Validation and performance

    Summary and outlook

  • NanoMet3  valida@on  @  60nm

    NM3  (DF  10)  vs  PMP  (DF  1000)  NM3  (DF  100)  vs  PMP  (DF  1000)  NM3  (DF  300)  vs  PMP  (DF  1000)  Linear  NM3  (DF  10)  vs  PMP  (DF  1000)

  • NanoMet3  valida@on  @  85nm

    NM3  (DF  10)  vs  PMP  (DF  1000)  NM3  (DF  100)  vs  PMP  (DF  1000)  NM3  (DF  300)  vs  PMP  (DF  1000)  Linear  NM3  (DF  10)  vs  PMP  (DF  1000)

  • Outlook  -‐  Field  Measurement

  • Outlook  -‐  Field  Measurement

  • Thanks very much