Sheet2Table S2. The complete annotation spreadsheet for the M. domestica predicted gene setGENElength (nt)TSA entrysubmitted TSA annotationD. melanogaster blastx hitFBgn numberGeneral FunctionDetailed FunctionSFAM#SFAMPfam Clan#Pfam ClanPfam#Pfam (short name)PfamKEGG#KEGGEnzyme Commission #GO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsGO termsALHF_00001.g11920KA644422Inward rectifier potassium channelIr-PBFBgn0039061OtherUnknown function81296E set domainsCL0030Ion_channelPF01007.15IRKInward rectifier potassium channel------GO:0005242GO:0015272ALHF_00004.g31686KA644423PRMT5 arginine-N-methyltransferaseArt4-PAFBgn0037770MetabolismTransferases53335S-adenosyl-L-methionine-dependent methyltransferasesCL0063NADP_RossmannPF05185.11PRMT5PRMT5 arginine-N-methyltransferaseK05931histone-arginine methyltransferase CARM1[EC:2.1.1.125]GO:0008469GO:0016274GO:0035241GO:0035242GO:0042054ALHF_00005.g4819KA649890hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00006.g5775KA649891FMN-binding domain protein----NONAnot annotatedNONANONA\N\NPF04205.9FMN_bindFMN-binding domain------ALHF_00013.g91467KA644424Sodium:dicarboxylate symporter family proteinEaat2-PDFBgn0026438Intra-cellular processesTransport118215Proton glutamate symport protein\N\NPF00375.13SDFSodium:dicarboxylate symporter family------GO:0005369GO:0015183GO:0015501GO:0017153ALHF_00014.g103246KA644425Sulfatase proteinSulf1-PAFBgn0040271MetabolismOther enzymes53649Alkaline phosphatase-like\N\NPF12548.3DUF3740Sulfatase proteinK14607SULF; extracellular sulfatase Sulf[EC:3.1.6.-]GO:0008449GO:0018741ALHF_00016.g121620KA644426Dedicator of cytokinesisCG11376-PAFBgn0031216NONAnot annotatedNONANONA\N\NPF06920.8Ded_cytoDedicator of cytokinesis------GO:0005085GO:0005525GO:0051020ALHF_00017.g13936KA644427GDSL-like Lipase/AcylhydrolaseCG7365-PAFBgn0036939MetabolismOther enzymes52266SGNH hydrolaseCL0264SGNH_hydrolasePF00657.17Lipase_GDSLGDSL-like Lipase/Acylhydrolase------GO:0004620ALHF_00020.g141278KA644428Ras family proteinRgk3-PCFBgn0085426GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00071.17RasRas family------GO:0003924GO:0005525ALHF_00024.g17795KA644429hypothetical proteinMed-PAFBgn0000547Extra-cellular processesCell adhesion48726ImmunoglobulinCL0357SMAD-FHAPF03166.9MH2MH2 domainK04501SMAD4; mothers against decapentaplegic homolog 4--GO:0005515ALHF_00025.g182049KA644430RING-variant proteinCG4080-PBFBgn0035983InformationDNA replication/repair57850RING/U-boxCL0229RINGPF12906.2RINGvRING-variant domainK10656E3 ubiquitin-protein ligase[EC:6.3.2.19]GO:0008270ALHF_00026.g19477KA644431Histidine phosphatase superfamily (branch 2)CG9452-PAFBgn0036877MetabolismOther enzymes53254Phosphoglycerate mutase-likeCL0071PGMPF00328.17His_Phos_2Histidine phosphatase superfamily (branch 2)K01078E3.1.3.2; acid phosphatase[EC:3.1.3.2]GO:0003993ALHF_00027.g201242KA649892hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00028.g211497KA644432TraL proteineya-PCFBgn0000320NONAnot annotatedNONANONA\N\NPF07178.6TraLTraL proteinK15616EYA1; eyes absent homolog 1[EC:3.1.3.48]GO:0004722GO:0004725GO:0008134GO:0016787GO:0019204GO:0042577ALHF_00029.g221824KA644433DIRP proteinmip130-PAFBgn0023509NONAnot annotatedNONANONA\N\NPF06584.8DIRPDIRP------GO:0003677ALHF_00029.g231062KA644434hypothetical proteineIF2B-epsilon-PBFBgn0023512GeneralGeneral48371ARM repeatCL0020TPRPF02020.13W2eIF4-gamma/eIF5/eIF2-epsilonK03240EIF2B5; translation initiation factor eIF-2B subunit epsilon--GO:0003743GO:0005085GO:0016779ALHF_00031.g241203KA644435hypothetical proteinwah-PFFBgn0262527NONAnot annotatedNONANONA----------------GO:0004812GO:0005524ALHF_00033.g255652KA644436EGF-like proteincrb-PAFBgn0259685MetabolismSecondary metabolism49899Concanavalin A-like lectins/glucanasesCL0001EGFPF00008.22EGFEGF-like domain------GO:0005080GO:0005509GO:0030507ALHF_00038.g271107KA649893FAT domain proteinNipped-A-PEFBgn0053554RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0020TPRPF02259.18FATFAT domainK08874TRRAP; transformation/transcription domain-associated protein--GO:0004672GO:0016773ALHF_00040.g28678KA649894DEAD/DEAH box helicasepea-PAFBgn0086895GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00270.24DEADDEAD/DEAH box helicaseK12818DHX8, PRP22; ATP-dependent RNA helicase DHX8/PRP22[EC:3.6.4.13]ALHF_00044.g291095KA649895MAM domain proteinNlg1-PEFBgn0051146MetabolismOther enzymes53474alpha/beta-HydrolasesCL0202GBDPF00629.18MAMMAM domain------GO:0004091GO:0042043ALHF_00046.g301170KA644437G-protein alpha subunitGalpha73B-PAFBgn0010223GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00503.15G-alphaG-protein alpha subunitK04640GNA; guanine nucleotide-binding protein subunit alpha, other--GO:0003924GO:0004871GO:0019001ALHF_00047.g31570KA649896Opacity-associated protein A LysM-like domain proteinPcf11-PDFBgn0022063Intra-cellular processesTransport48464ENTH/VHS domainCL0187LysMPF04225.7OapAOpacity-associated protein A LysM-like domain------ALHF_00048.g32690KA644438nucleotidaseCG42249-PBFBgn0259101Intra-cellular processesProteases56300Metallo-dependent phosphatases\N\NPF02872.135_nucleotid_C5'-nucleotidase, C-terminal domainK01081E3.1.3.5; 5'-nucleotidase[EC:3.1.3.5]GO:0000166GO:0008253GO:0017110GO:0017111GO:0046872ALHF_00052.g332055KA644439Ubiquitin-conjugating enzymeCG10254-PAFBgn0027512Intra-cellular processesProtein modification54495UBC-likeCL0208UBCPF00179.21UQ_conUbiquitin-conjugating enzymeK10581UBE2O; ubiquitin-conjugating enzyme E2 O[EC:6.3.2.19]GO:0004842ALHF_00058.g341020KA649897MH1 domain proteinSmox-PAFBgn0025800RegulationDNA-binding49879SMAD/FHA domainCL0263His-Me_fingerPF03165.11MH1MH1 domainK04500SMAD2_3; mothers against decapentaplegic homolog 2/3--GO:0003700GO:0005072GO:0005515ALHF_00059.g35543KA649898Ubiquitin carboxyl-terminal hydrolaseCG30421-PAFBgn0050421Intra-cellular processesProteases54001Cysteine proteinasesCL0125Peptidase_CAPF00443.24UCHUbiquitin carboxyl-terminal hydrolaseK11852USP31; ubiquitin carboxyl-terminal hydrolase 31[EC:3.1.2.15]GO:0004221ALHF_00061.g36936KA644440Scavenger mRNA decapping enzyme binding proteinCG2091-PAFBgn0037372MetabolismCarbohydrate m/tr54197HIT-likeCL0265HITPF11969.3DcpS_CScavenger mRNA decapping enzyme C-term bindingK12584DCPS, DCS; scavenger mRNA-decapping enzyme DcpS[EC:3.-.-.-]GO:0016787ALHF_00063.g371749KA644441PDZ domain proteinCG31342-PBFBgn0051342RegulationSignal transduction50729PH domain-likeCL0466PDZ-likePF00595.19PDZPDZ domain (Also known as DHR or GLGF)------ALHF_00064.g382100KA644442Peptidase family M3CG7791-PAFBgn0033038Intra-cellular processesProteases55486Metalloproteases ("zincins"), catalytic domainCL0126Peptidase_MAPF01432.15Peptidase_M3Peptidase family M3K01410E3.4.24.59, MIPEP; mitochondrial intermediate peptidase[EC:3.4.24.59]GO:0004222ALHF_00067.g401021KA649899Trypsingrass-PBFBgn0039494Intra-cellular processesProteases50494Trypsin-like serine proteasesCL0124Peptidase_PAPF00089.21TrypsinTrypsin------GO:0004252ALHF_00072.g43892KA649900Amino acid permeaseJhI-21-PCFBgn0028425NONAnot annotatedNONANONACL0062APCPF13520.1AA_permease_2Amino acid permease------GO:0015171GO:0015179ALHF_00075.g462055KA644443PWWP domain proteinBr140-PAFBgn0033155RegulationDNA-binding47370BromodomainCL0049TudorPF00855.12PWWPPWWP domainK11348BRPF1; bromodomain and PHD finger-containing protein 1--GO:0003676GO:0008270ALHF_00076.g47552KA644444Zinc ribbon proteinhiw-PAFBgn0003996GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0167Zn_Beta_RibbonPF09723.5CxxC_CxxC_SSSSZinc ribbon domainK10693MYCBP2, PAM; E3 ubiquitin-protein ligase MYCBP2[EC:6.3.2.19]GO:0004888GO:0005395GO:0005524GO:0042626ALHF_00078.g481149KA644445Sodium:neurotransmitter symporter family proteinList-PCFBgn0034381NONAnot annotatedNONANONA\N\NPF00209.13SNFSodium:neurotransmitter symporter familyK05038SLC6A5S; solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14--GO:0005326GO:0005328GO:0017032ALHF_00080.g491266KA644446MarB protein----NONAnot annotatedNONANONA\N\NPF13999.1MarBMarB protein------ALHF_00083.g502160KA644447Diacylglycerol kinase accessory proteinrdgA-PGFBgn0261549MetabolismOther enzymes111331NAD kinase/diacylglycerol kinase-like\N\NPF00609.14DAGK_accDiacylglycerol kinase accessory domain------GO:0004143GO:0019992ALHF_00084.g512286KA644448AnkyrinCG10011-PAFBgn0039590GeneralProtein interaction48403Ankyrin repeatCL0465AnkPF12796.2Ank_2Ankyrin repeats (3 copies)------GO:0003674ALHF_00087.g531998KA644449GC-rich sequence DNA-binding factor-like proteinCG1965-PAFBgn0037466NONAnot annotatedNONANONA\N\NPF07842.7GCFCFAD dependent oxidoreductaseK13211GCFC; GC-rich sequence DNA-binding factor--GO:0003677GO:0003700ALHF_00089.g551212KA644450Sugar (and other) transporterCG8837-PAFBgn0031520Intra-cellular processesIon m/tr103473MFS general substrate transporterCL0015MFSPF00083.19Sugar_trSugar (and other) transporter------GO:0022857ALHF_00095.g56985KA649901HelicaseXNP-PBFBgn0039338GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00271.26Helicase_CHelicase conserved C-terminal domain------ALHF_00096.g57921KA644451hypothetical protein----NONAnot annotatedNONANONA\N\NPF06696.6Strep_SA_repStreptococcal surface antigen repeat------ALHF_00102.g584371KA649902Ribonuclease 3Dcr-2-PAFBgn0034246InformationRNA processing69065RNase III domain-like\N\NPF00636.21Ribonuclease_3Ribonuclease III domain------ALHF_00103.g594770KA644452Low-density lipoprotein receptor domain class Ayl-PBFBgn0004649MetabolismLipid m/tr63825YWTD domain\N\NPF00057.13Ldl_recept_aLow-density lipoprotein receptor domain class A------GO:0005509GO:0008196ALHF_00110.g62527KA649903Prolyl oligopeptidase familyCG9059-PDFBgn0030810MetabolismOther enzymes53474alpha/beta-HydrolasesCL0028AB_hydrolasePF00326.16Peptidase_S9Prolyl oligopeptidase family------GO:0008236GO:0008239ALHF_00120.g651284KA644453Oxidoreductase molybdopterin binding proteinCG7280-PAFBgn0030966MetabolismE- transfer56524Oxidoreductase molybdopterin-binding domain\N\NPF00174.14Oxidored_molybOxidoreductase molybdopterin binding domainK00387E1.8.3.1, SUOX; sulfite oxidase[EC:1.8.3.1]GO:0008482GO:0009055GO:0020037GO:0030151ALHF_00121.g661053KA644454Peptidase family M13CG5527-PAFBgn0039564Intra-cellular processesProteases55486Metalloproteases ("zincins"), catalytic domainCL0126Peptidase_MAPF01431.16Peptidase_M13Peptidase family M13------GO:0004222ALHF_00127.g67630KA644455Cohesin loading factorCG4203-PAFBgn0038300GeneralProtein interaction48452TPR-likeCL0020TPRPF10345.4Cohesin_loadCohesin loading factorK11266MAU2; MAternally affected uncoordination--GO:0005488ALHF_00129.g68871KA649904YjeF proteineast-PDFBgn0261954NONAnot annotatedNONANONACL0063NADP_RossmannPF03853.10YjeF_NYjeF-related protein N-terminus------ALHF_00130.g691698KA649905hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00132.g701893KA649906hypothetical proteinmahj-PBFBgn0034641GeneralGeneral50978WD40 repeat-like----------K11789VPRBP, DCAF1; HIV-1 Vpr-binding protein--GO:0005488ALHF_00134.g714773KA644456Sec7 domain proteinsec71-PBFBgn0028538RegulationOther regulatory function48425Sec7 domain\N\NPF01369.15Sec7Sec7 domain------GO:0005086GO:0005488ALHF_00135.g72921KA644457SH3 domain proteinCG30372-PCFBgn0050372GeneralProtein interaction103657BAR/IMD domain-likeCL0010SH3PF00018.23SH3_1SH3 domainK12488ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein--GO:0005543GO:0008060GO:0008270ALHF_00137.g731080KA644458C2H2-type zinc fingersu(Hw)-PCFBgn0003567RegulationDNA-binding57667beta-beta-alpha zinc fingersCL0361C2H2-zfPF13894.1zf-C2H2_4C2H2-type zinc finger------GO:0003677GO:0005515GO:0008270GO:0043035ALHF_00141.g741323KA644459Lipid A 3-O-deacylaseCG10062-PBFBgn0034439Intra-cellular processesProteases53187Zn-dependent exopeptidasesCL0193MBBPF09411.5PagLLipid A 3-O-deacylase (PagL)------GO:0008233ALHF_00142.g752271KA644460Integrin, beta chainbetaInt-nu-PAFBgn0010395Extra-cellular processesCell adhesion53300vWA-like\N\NPF00362.13Integrin_betaIntegrin, beta chain------GO:0004872GO:0050839ALHF_00143.g761344KA644461Glycosyl hydrolaseCG5613-PBFBgn0030839NONAnot annotatedNONANONA\N\NPF03644.8Glyco_hydro_85Glycosyl hydrolase family 85K01227E3.2.1.96; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase[EC:3.2.1.96]GO:0005515GO:0033925ALHF_00145.g771467KA644462RNA recognition proteinCG1316-PAFBgn0035526RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF00076.17RRM_1RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)------GO:0000166GO:0003676GO:0003729ALHF_00147.g78711KA644463Helix-loop-helix DNA-binding proteinnet-PBFBgn0002931RegulationDNA-binding47459HLH, helix-loop-helix DNA-binding domain\N\NPF00010.21HLHHelix-loop-helix DNA-binding domain------GO:0003700ALHF_00148.g79538KA649907Sec1 familycar-PAFBgn0000257Intra-cellular processesTransport56815Sec1/munc18-like (SM) proteins\N\NPF00995.18Sec1Sec1 family------GO:0000149GO:0005515ALHF_00150.g811701KA644464RNA recognition proteinheph-PVFBgn0011224RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF13893.1RRM_5RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)K14948PTBP2, NPTB; olypyrimidine tract-binding protein 2--GO:0000166GO:0000900GO:0003729GO:0003730GO:0008187ALHF_00154.g83540KA644465WW domain-binding protein 1CG13004-PDFBgn0030797NONAnot annotatedNONANONA\N\NPF11669.3WBP-1WW domain-binding protein 1------ALHF_00155.g841791KA644466Cation transporting ATPaseSPoCk-PFFBgn0052451Intra-cellular processesIon m/tr81665Calcium ATPase, transmembrane domain M\N\NPF00689.16Cation_ATPase_CCation transporting ATPase, C-terminusK01537E3.6.3.8; Ca2+-transporting ATPase[EC:3.6.3.8]GO:0005388GO:0005524GO:0015410GO:0046872ALHF_00159.g864293KA644467Dual specificity phosphatasessh-PAFBgn0029157RegulationKinases/phosphatases52799(Phosphotyrosine protein) phosphatases IICL0031PhosphatasePF00782.15DSPcDual specificity phosphatase, catalytic domainK05766SSH; slingshot--GO:0004725GO:0008138GO:0008330GO:0017017ALHF_00160.g87528KA644468Cytochrome P450Cyp4aa1-PBFBgn0034053MetabolismRedox48264Cytochrome P450\N\NPF00067.17p450Cytochrome P450K15001CYP4; cytochrome P450, family 4[EC:1.14.-.-]GO:0004497GO:0009055GO:0016705GO:0020037ALHF_00162.g882175KA644469hypothetical proteinCG9715-PAFBgn0036668OtherViral proteins57756Retrovirus zinc finger-like domains----------------GO:0003676GO:0008270ALHF_00168.g891257KA644470PAP2 superfamily proteinwun-PBFBgn0016078MetabolismRedox48317Acid phosphatase/Vanadium-dependent haloperoxidaseCL0525pap2PF01569.16PAP2PAP2 superfamilyK01080PPAP2; phosphatidate phosphatase[EC:3.1.3.4]GO:0008195GO:0016791GO:0042803ALHF_00175.g91477KA649908Helix-loop-helix DNA-binding domain proteincyc-PAFBgn0023094RegulationSignal transduction55785PYP-like sensor domain (PAS domain)\N\NPF00010.21HLHHelix-loop-helix DNA-binding domainK02296ARNTL, BMAL1, CYC; aryl hydrocarbon receptor nuclear translocator-like protein 1--GO:0000977GO:0003677GO:0003700GO:0004871GO:0046982ALHF_00176.g923843KA644471IKI3 familyElp1-PAFBgn0037926Intra-cellular processesProteases69322Tricorn protease domain 2CL0186Beta_propellerPF04762.7IKI3IKI3 familyK11373ELP1, IKI3, IKBKAP; elongator complex protein 1--GO:0008607ALHF_00186.g931875KA644472RhoGEF domain proteinCG30456-PCFBgn0050456RegulationSignal transduction48065DBL homology domain (DH-domain)\N\NPF00621.15RhoGEFRhoGEF domain------GO:0005089GO:0005543ALHF_00187.g941872KA644473Glycosyl transferaseGalNAc-T1-PBFBgn0034025MetabolismTransferases53448Nucleotide-diphospho-sugar transferasesCL0110GT-APF00535.21Glycos_transf_2Glycosyl transferase family 2K00710GALNT; polypeptide N-acetylgalactosaminyltransferase[EC:2.4.1.41]GO:0004653ALHF_00188.g954233KA644474ATP-dependent proteaseCG32369-PCFBgn0052369RegulationRNA binding, m/tr88697PUA domain-likeCL0178PUAPF02190.11LONATP-dependent protease La (LON) domain------GO:0004176GO:0008270ALHF_00189.g96772KA649909Biopolymer transport protein ExbD/TolR----NONAnot annotatedNONANONA\N\NPF02472.11ExbDBiopolymer transport protein ExbD/TolR------ALHF_00193.g971116KA644475PHD-fingerIng3-PAFBgn0030945InformationDNA replication/repair57903FYVE/PHD zinc fingerCL0390zf-FYVE-PHDPF00628.24PHDPHD-fingerK11319ING3; inhibitor of growth protein 3--GO:0008270ALHF_00195.g98732KA644476hypothetical proteinCG8303-PBFBgn0034143GeneralSmall molecule binding51735NAD(P)-binding Rossmann-fold domains\N\NPF03015.14SterileMale sterility protein------GO:0000166GO:0016620ALHF_00197.g99540KA644477Cleavage and polyadenylation factor 2Cpsf100-PBFBgn0027873MetabolismRedox56281Metallo-hydrolase/oxidoreductase\N\NPF13299.1CPSF100_CCleavage and polyadenylation factor 2 C-terminalK14402CPSF2, CFT2; cleavage and polyadenylation specificity factor subunit 2--GO:0003730GO:0016787ALHF_00199.g1001245KA649910hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00200.g1012154KA644478hypothetical proteinCed-12-PAFBgn0032409RegulationSignal transduction50729PH domain-like\N\NPF11841.3DUF3361Domain of unknown function (DUF3361)K12366ELMO1, CED12; engulfment and cell motility protein 1--GO:0005488ALHF_00208.g1023117KA644479FERM central domain proteinyrt-PDFBgn0004049RegulationSignal transduction50729PH domain-like\N\NPF00373.13FERM_MFERM central domain------GO:0008092ALHF_00209.g1031473KA644480CD36 family proteincrq-PCFBgn0015924NONAnot annotatedNONANONA\N\NPF01130.16CD36CD36 family------GO:0005044ALHF_00210.g1045031KA644481Amylo-alpha-1,6-glucosidaseCG9485-PBFBgn0034618MetabolismCarbohydrate m/tr48208Six-hairpin glycosidasesCL00596_HairpinPF06202.9GDE_CAmylo-alpha-1,6-glucosidaseK01196AGL; glycogen debranching enzyme[EC:2.4.1.253.2.1.33]GO:0004134GO:0004135GO:0043169ALHF_00217.g105627KA644482SNARE domain proteinSnap24-PAFBgn0028401Intra-cellular processesTransport58038SNARE fusion complexCL0445SNARE-fusionPF05739.14SNARESNARE domainK08508SNAP23; synaptosomal-associated protein, 23kDa--GO:0005483ALHF_00219.g1061041KA644483Activator of Hsp90 ATPaseCG1416-PCFBgn0032961MetabolismOther enzymes103111Activator of Hsp90 ATPase, Aha1\N\NPF09229.6Aha1_NActivator of Hsp90 ATPase, N-terminal------GO:0001671GO:0051087ALHF_00221.g107579KA644484Translocon-associated protein, gamma subunit (TRAP-gamma)CG5885-PAFBgn0025700NONAnot annotatedNONANONA\N\NPF07074.7TRAP-gammaTranslocon-associated protein, gamma subunit (TRAP-gamma)K13251SSR3; translocon-associated protein subunit gamma--ALHF_00223.g108651KA649911HEAT-like repeat proteinTrn-PCFBgn0024921GeneralGeneral48371ARM repeatCL0020TPRPF13513.1HEAT_EZHEAT-like repeat------GO:0005488GO:0008320ALHF_00227.g1092983KA649912Ligand-gated ion channelclumsy-PBFBgn0026255Intra-cellular processesIon m/tr53850Periplasmic binding protein-like IICL0030Ion_channelPF00060.21Lig_chanLigand-gated ion channel------GO:0004970GO:0005234GO:0015277ALHF_00228.g110786KA644485Ubiquitin-conjugating enzymeCG7656-PEFBgn0036516Intra-cellular processesProtein modification54495UBC-likeCL0208UBCPF00179.21UQ_conUbiquitin-conjugating enzymeK02207UBE2R, UBC3, CDC34; ubiquitin-conjugating enzyme E2 R[EC:6.3.2.19]GO:0004842ALHF_00229.g111936KA644486RNA recognition proteinRb97D-PIFBgn0004903RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF00076.17RRM_1RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)------GO:0000166GO:0003676GO:0003729ALHF_00232.g112708KA644487Chitin binding Peritrophin-A domain proteinobst-E-PBFBgn0031737MetabolismCarbohydrate m/tr57625Invertebrate chitin-binding proteinsCL0155CBM_14_19PF01607.19CBM_14Chitin binding Peritrophin-A domain------GO:0008061GO:0016490ALHF_00238.g113990KA644488Autophagocytosis associated protein (Atg3),Aut1-PAFBgn0036813NONAnot annotatedNONANONA\N\NPF03986.8Autophagy_NAutophagocytosis associated protein (Atg3), N-terminal domainK08343ATG3; autophagy-related protein 3--ALHF_00242.g1141197KA644489AIR synthase proteinSelD-PAFBgn0261270MetabolismOther enzymes56042PurM C-terminal domain-like\N\NPF02769.17AIRS_CAIR synthase related protein, C-terminal domainK01008selD, SEPHS; selenide, water dikinase[EC:2.7.9.3]GO:0004756GO:0005524ALHF_00246.g115324KA644490Transcription initiation factor 2ATfIIA-S-PAFBgn0013347RegulationDNA-binding47396Transcription factor IIA (TFIIA), alpha-helical domain\N\NPF02268.11TFIIA_gamma_NTranscription initiation factor IIA, gamma subunit, helical domainK03123TFIIA2, GTF2A2, TOA2; transcription initiation factor TFIIA small subunit--GO:0001128GO:0001129ALHF_00247.g116435KA644491TropomyosinTm2-PCFBgn0004117Intra-cellular processesCell motility57997TropomyosinCL0452Tropomyosin-lkePF00261.15TropomyosinTropomyosinK10374TPM2; tropomyosin 2--GO:0003779ALHF_00248.g117435KA644492TropomyosinTm2-PBFBgn0004117Intra-cellular processesCell motility57997TropomyosinCL0452Tropomyosin-lkePF00261.15TropomyosinTropomyosinK10374TPM2; tropomyosin 2--ALHF_00251.g118882KA644493Phospholipase A2GIIIspla2-PBFBgn0030013NONAnot annotatedNONANONA\N\NPF05826.7Phospholip_A2_2Phospholipase A2K01047PLA2G; phospholipase A2[EC:3.1.1.4]GO:0004623GO:0005509ALHF_00252.g119735KA644494Replication protein ARPA2-PAFBgn0032906InformationDNA replication/repair50249Nucleic acid-binding proteinsCL0123HTHPF08784.6RPA_CReplication protein A C terminalK10739RFA2, RPA2; replication factor A2--GO:0003677ALHF_00253.g1201653KA644495Papain family cysteine protease26-29-p-PAFBgn0250848Intra-cellular processesProteases54001Cysteine proteinasesCL0125Peptidase_CAPF00112.18Peptidase_C1Papain family cysteine protease------GO:0004197ALHF_00254.g1211551KA644496Coenzyme A transferaseCG1140-PAFBgn0035298MetabolismTransferases100950NagB/RpiA/CoA transferase-likeCL0246ISOCOT_FoldPF01144.18CoA_transCoenzyme A transferaseK01027OXCT; 3-oxoacid CoA-transferase[EC:2.8.3.5]GO:0008260ALHF_00255.g122483KA644497Eukaryotic elongation factoreIF-5A-PAFBgn0034967InformationTranslation50104Translation proteins SH3-like domainCL0021OBPF01287.15eIF-5aEukaryotic elongation factor 5A hypusine, DNA-binding OB foldK03263EIF5A; translation initiation factor 5A--GO:0003743GO:0003746GO:0043022GO:0045182ALHF_00260.g1241515KA644498ABC-2 type transporterAtet-PDFBgn0020762GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0181ABC-2PF01061.19ABC2_membraneABC-2 type transporter------GO:0005215GO:0005524GO:0042626ALHF_00264.g125993KA644499ThioredoxinCG5554-PAFBgn0034914MetabolismRedox52833Thioredoxin-likeCL0172ThioredoxinPF00085.15ThioredoxinThioredoxin------GO:0003756ALHF_00265.g1263513KA644500FYVE zinc finger proteinCG6051-PCFBgn0039492InformationDNA replication/repair57903FYVE/PHD zinc fingerCL0390zf-FYVE-PHDPF01363.16FYVEFYVE zinc finger------GO:0046872ALHF_00266.g127342KA644501HMG (high mobility group) boxHmgD-PCFBgn0004362RegulationDNA-binding47095HMG-boxCL0114HMG-boxPF00505.14HMG_boxHMG (high mobility group) box------GO:0003680GO:0008301ALHF_00267.g1281512KA644502Adenosine/AMP deaminaseAdgf-D-PAFBgn0038172MetabolismOther enzymes51556Metallo-dependent hydrolasesCL0034AmidohydrolasePF00962.17A_deaminaseAdenosine/AMP deaminaseK01488E3.5.4.4, ADA, add; adenosine deaminase[EC:3.5.4.4]GO:0004000GO:0008083ALHF_00274.g129471KA649913SH3-binding, glutamic acid-rich proteinSh3beta-PEFBgn0035772MetabolismRedox52833Thioredoxin-likeCL0172ThioredoxinPF04908.10SH3BGRSH3-binding, glutamic acid-rich protein------ALHF_00275.g1301659KA644503Pyridoxal-dependent decarboxylaseSply-PAFBgn0010591MetabolismTransferases53383PLP-dependent transferasesCL0061PLP_aminotranPF00282.14Pyridoxal_deCPyridoxal-dependent decarboxylase conserved domainK01634E4.1.2.27; sphinganine-1-phosphate aldolase[EC:4.1.2.27]GO:0008117GO:0016831GO:0030170ALHF_00276.g1312331KA644504Surp moduleCG16941-PAFBgn0038464RegulationRNA binding, m/tr109905Surp module (SWAP domain)\N\NPF01805.15SurpSurp moduleK12825SF3A1, SAP114; splicing factor 3A subunit 1--GO:0003723ALHF_00277.g132954KA644505Aldo/keto reductaseCG6084-PBFBgn0086254MetabolismRedox51430NAD(P)-linked oxidoreductase\N\NPF00248.16Aldo_ket_redAldo/keto reductase familyK00011E1.1.1.21, AKR1; aldehyde reductase[EC:1.1.1.21]GO:0004032ALHF_00278.g133954KA644506Aldo/keto reductaseCG6084-PAFBgn0086254MetabolismRedox51430NAD(P)-linked oxidoreductase\N\NPF00248.16Aldo_ket_redAldo/keto reductase familyK00011E1.1.1.21, AKR1; aldehyde reductase[EC:1.1.1.21]ALHF_00279.g134507KA644507Ubiquitin-conjugating enzymeCG40045-PAFBgn0058045Intra-cellular processesProtein modification54495UBC-likeCL0208UBCPF00179.21UQ_conUbiquitin-conjugating enzymeK10575UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1[EC:6.3.2.19]GO:0016881ALHF_00281.g135456KA644508Ribosomal S13/S15RpS13-PBFBgn0010265RegulationRNA binding, m/tr47060S15/NS1 RNA-binding domain\N\NPF08069.7Ribosomal_S13_NRibosomal S13/S15 N-terminal domainK02953RP-S13e, RPS13; small subunit ribosomal protein S13e--GO:0003735ALHF_00282.g1362220KA644509Peptidase family M41CG3499-PBFBgn0034792GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0126Peptidase_MAPF01434.13Peptidase_M41Peptidase family M41K08955YME1; ATP-dependent metalloprotease[EC:3.4.24.-]GO:0004176GO:0004222GO:0005524ALHF_00283.g1371728KA644510NUMB domain proteinnumb-PAFBgn0002973RegulationSignal transduction50729PH domain-like\N\NPF06311.7NumbFNUMB domainK06057NUMBL; numb--GO:0003676GO:0005112GO:0005515ALHF_00284.g138810KA644511Ribosomal protein S5RpS2-PAFBgn0004867InformationTranslation54211Ribosomal protein S5 domain 2-likeCL0196DSRMPF00333.15Ribosomal_S5Ribosomal protein S5, N-terminal domainK02981RP-S2e, RPS2; small subunit ribosomal protein S2e--GO:0003723GO:0003735ALHF_00285.g1391893KA644512Glypicandally-PBFBgn0011577NONAnot annotatedNONANONA\N\NPF01153.14GlypicanGlypicanK02306DALLY; dally--ALHF_00287.g1401674KA644513Zinc finger, C2H2 typecbt-PCFBgn0043364RegulationDNA-binding57667beta-beta-alpha zinc fingersCL0361C2H2-zfPF00096.21zf-C2H2Zinc finger, C2H2 typeK13943CBT; cabut--GO:0000981GO:0008270GO:0043565ALHF_00288.g1411098KA644514Phosphatidylglycerophosphatase Acomm3-PDFBgn0259236NONAnot annotatedNONANONA\N\NPF04608.8PgpAPhosphatidylglycerophosphatase A------ALHF_00292.g142645KA644515Iron/manganese superoxide dismutaseSod2-PAFBgn0010213MetabolismRedox54719Fe,Mn superoxide dismutase (SOD), C-terminal domain\N\NPF02777.13Sod_Fe_CIron/manganese superoxide dismutases, C-terminal domainK04564E1.15.1.1A, sodA, sodB, SOD2; superoxide dismutase, Fe-Mn family[EC:1.15.1.1]GO:0004784GO:0016209GO:0046872ALHF_00293.g143552KA649914RNA recognition proteinAly-PAFBgn0010774RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF00076.17RRM_1RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)K12881THOC4, ALY; THO complex subunit 4--ALHF_00295.g144582KA644516Ribosomal protein S3RpS3-PAFBgn0002622InformationTranslation54821Ribosomal protein S3 C-terminal domain\N\NPF00189.15Ribosomal_S3_CRibosomal protein S3, C-terminal domainK02985RP-S3e, RPS3; small subunit ribosomal protein S3e--GO:0003723GO:0003735GO:0003906GO:0008534ALHF_00296.g145963KA644517Sodium / potassium ATPase beta chainnrv2-PEFBgn0015777NONAnot annotatedNONANONA\N\NPF00287.13Na_K-ATPaseSodium / potassium ATPase beta chainK01540ATP1B; sodium/potassium-transporting ATPase subunit beta--GO:0005391GO:0008324ALHF_00298.g1461821KA644518cyclic nucleotide phosphodiesterasednc-PCFBgn0000479MetabolismOther enzymes109604HD-domain/PDEase-likeCL0237HD_PDEasePF00233.14PDEase_I3'5'-cyclic nucleotide phosphodiesteraseK01120PDE; 3',5'-cyclic-nucleotide phosphodiesterase[EC:3.1.4.17]GO:0004114GO:0004115ALHF_00299.g147540KA644519Hsp20/alpha crystallin familyHsp23-PBFBgn0001224Intra-cellular processesProtein modification49764HSP20-like chaperonesCL0190HSP20PF00011.16HSP20Hsp20/alpha crystallin family------GO:0003779GO:0005515ALHF_00300.g148606KA644520Ribosomal protein S11mRpS11-PAFBgn0038474InformationTranslation53137Translational machinery componentsCL0267S11_L18pPF00411.14Ribosomal_S11Ribosomal protein S11------GO:0003735ALHF_00301.g1493066KA644521exonucleaseegl-PBFBgn0000562MetabolismNucleotide m/tr53098Ribonuclease H-likeCL0219RNase_HPF01612.15DNA_pol_A_exo13'-5' exonuclease------GO:0003729GO:0008408ALHF_00305.g150330KA644522C-terminal domain of 1-Cys peroxiredoxinPrx6005-PAFBgn0031479MetabolismRedox52833Thioredoxin-like\N\NPF10417.41-cysPrx_CC-terminal domain of 1-Cys peroxiredoxinK11188PRDX6; peroxiredoxin 6, 1-Cys peroxiredoxin[EC:1.11.1.71.11.1.153.1.1.-]GO:0004601GO:0004602GO:0008379GO:0016209ALHF_00306.g1516048KA644523putative domainStrn-Mlck-PQFBgn0013988RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0011IgPF07679.11I-setImmunoglobulin I-set domain------GO:0004674GO:0004683GO:0004687GO:0005200GO:0005524ALHF_00307.g1525025KA644524putative domainStrn-Mlck-PQFBgn0013988RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0011IgPF07679.11I-setImmunoglobulin I-set domain------ALHF_00309.g153906KA644525TetraspaninTsp29Fb-PCFBgn0032075Extra-cellular processesImmune response48652TetraspaninCL0347TetraspanninPF00335.15TetraspanninTetraspanin family------GO:0003674ALHF_00310.g1541485KA644526AnkyrincenB1A-PBFBgn0039056GeneralProtein interaction103657BAR/IMD domain-likeCL0465AnkPF12796.2Ank_2Ankyrin repeats (3 copies)K12489ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein--GO:0005543GO:0008060GO:0008270ALHF_00313.g155672KA644527Pyridoxamine 5'-phosphate oxidaseCREG-PDFBgn0025456MetabolismCoenzyme m/tr50475FMN-binding split barrelCL0336FMN-bindingPF13883.1Pyrid_oxidase_2Pyridoxamine 5'-phosphate oxidase------GO:0008134GO:0010181GO:0016491ALHF_00314.g156942KA644528Sodium / potassium ATPase beta chainnrv1-PAFBgn0015776NONAnot annotatedNONANONA\N\NPF00287.13Na_K-ATPaseSodium / potassium ATPase beta chainK01540ATP1B; sodium/potassium-transporting ATPase subunit beta--GO:0005391GO:0005515GO:0008324ALHF_00315.g157963KA644529Mitochondrial carrier proteinMtch-PGFBgn0027786Intra-cellular processesTransport103506Mitochondrial carrier\N\NPF00153.22Mito_carrMitochondrial carrier protein------GO:0022857ALHF_00316.g1581743KA644530Major Facilitator Superfamily proteinCG8596-PAFBgn0035767Intra-cellular processesIon m/tr103473MFS general substrate transporterCL0015MFSPF07690.11MFS_1Major Facilitator SuperfamilyK12307MSFD8, CLN7; MFS transporter, ceroid-lipofuscinosis neuronal protein 7--ALHF_00317.g159537KA644531Apolipophorin-3 precursor----NONAnot annotatedNONANONA\N\NPF07464.6ApoLp-IIIApolipophorin-III precursor (apoLp-III)------ALHF_00321.g1601548KA644532RNA recognition proteinCG7903-PAFBgn0039730RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF00076.17RRM_1RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)------GO:0000166GO:0003676GO:0003729ALHF_00323.g161512KA649915PQ loop repeat proteinCG13784-PCFBgn0031897NONAnot annotatedNONANONACL0141MtN3-likePF04193.9PQ-loopPQ loop repeat------ALHF_00324.g1621032KA644533Glycosyl transferaseegh-PBFBgn0001404MetabolismTransferases53448Nucleotide-diphospho-sugar transferasesCL0110GT-APF13632.1Glyco_trans_2_3Glycosyl transferase family group 2K02359EGH; egghead protein (zeste-white 4 protein)--GO:0019187ALHF_00326.g1633585KA644534Myosin headjar-PKFBgn0011225GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00063.16Myosin_headMyosin head (motor domain)K10358MYO6; myosin VI--GO:0003774GO:0003779GO:0005515GO:0005516GO:0005524GO:0008017GO:0032027GO:0042623GO:0051015GO:0070856ALHF_00327.g1641536KA644535Sugar (and other) transporterGlut1-PDFBgn0261914NONAnot annotatedNONANONACL0015MFSPF00083.19Sugar_trSugar (and other) transporterK07299SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1--GO:0005355ALHF_00328.g165603KA644536Adenylate kinaseAdk1-PAFBgn0022709GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00406.17ADKAdenylate kinaseK00939E2.7.4.3, adk; adenylate kinase[EC:2.7.4.3]GO:0004017GO:0004849GO:0005524ALHF_00329.g166816KA644537Ribosomal protein L7Ae/L30e/S12e/Gadd45RpL7A-PDFBgn0014026InformationTranslation55315L30e-likeCL0101RNA_ribose_bindPF01248.21Ribosomal_L7AeRibosomal protein L7Ae/L30e/S12e/Gadd45 familyK02936RP-L7Ae, RPL7A; large subunit ribosomal protein L7Ae--GO:0003735ALHF_00330.g1672361KA644538Low-density lipoprotein receptor repeat class BMegalin-PAFBgn0002552NONAnot annotatedNONANONACL0186Beta_propellerPF00058.12Ldl_recept_bLow-density lipoprotein receptor repeat class BK06233LRP2; low density lipoprotein-related protein 2--GO:0003824ALHF_00333.g168927KA644539pfkB family carbohydrate kinaseCG7328-PAFBgn0036942MetabolismOther enzymes53613Ribokinase-likeCL0118RibokinasePF00294.19PfkBpfkB family carbohydrate kinaseK00846KHK; ketohexokinase[EC:2.7.1.3]GO:0004454ALHF_00334.g169570KA644540PRELI-like familymRpS34-PAFBgn0260460NONAnot annotatedNONANONA\N\NPF04707.9PRELIPRELI-like family------GO:0003735ALHF_00335.g1701023KA644541WD domain proteinGbeta13F-PFFBgn0001105GeneralGeneral50978WD40 repeat-likeCL0186Beta_propellerPF00400.27WD40WD domain, G-beta repeatK04536GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1--GO:0003924ALHF_00336.g171534KA644542Ribosomal L18 proteinRpL18A-PAFBgn0010409NONAnot annotatedNONANONA\N\NPF01775.12Ribosomal_L18aeRibosomal L18ae/LX protein domainK02882RP-L18Ae, RPL18A; large subunit ribosomal protein L18Ae--GO:0003735ALHF_00338.g172768KA644543Histidine phosphatase superfamily (branch 1)Pglym78-PCFBgn0014869MetabolismOther enzymes53254Phosphoglycerate mutase-likeCL0071PGMPF00300.17His_Phos_1Histidine phosphatase superfamily (branch 1)K01834gpmA, PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase[EC:5.4.2.1]GO:0004619ALHF_00340.g173498KA644544TB2/DP1, HVA22 family proteinCG8331-PBFBgn0033906NONAnot annotatedNONANONA\N\NPF03134.14TB2_DP1_HVA22TB2/DP1, HVA22 family------ALHF_00341.g174420KA644545cuticle proteinCpr49Aa-PBFBgn0050045NONAnot annotatedNONANONA\N\NPF00379.18Chitin_bind_4Insect cuticle protein------GO:0005214ALHF_00343.g1752577KA644546C2 domain proteinEsyt2-PBFBgn0039208RegulationSignal transduction49562C2 domain (Calcium/lipid-binding domain, CaLB)CL0154C2PF00168.25C2C2 domain------GO:0003674ALHF_00347.g1764330KA649916Myosin headMyo10A-PCFBgn0263705NONAnot annotatedNONANONACL0023P-loop_NTPasePF00063.16Myosin_headMyosin head (motor domain)K10361MYO15; myosin XV--ALHF_00352.g1771383KA644547KH domain proteinbl-PCFBgn0015907InformationRNA processing54791Eukaryotic type KH-domain (KH-domain type I)CL0007KHPF00013.24KH_1KH domainK12886HNRNPK; heterogeneous nuclear ribonucleoprotein K--GO:0003723GO:0003729GO:0008134ALHF_00353.g1782280KA644548RNA pseudouridylate synthaseRluA-1-PCFBgn0051719MetabolismNucleotide m/tr55120Pseudouridine synthase\N\NPF00849.17PseudoU_synth_2RNA pseudouridylate synthase------GO:0003723GO:0008835GO:0009982ALHF_00354.g1792334KA644549hypothetical proteincrm-PAFBgn0000376NONAnot annotatedNONANONA----------------GO:0003677GO:0003682ALHF_00355.g1804507KA649917DB moduleCG17839-PBFBgn0036454Extra-cellular processesCell adhesion49265Fibronectin type III\N\NPF01682.14DBDB module------ALHF_00356.g1811500KA644550TPR repeat proteinP58IPK-PAFBgn0037718GeneralProtein interaction48452TPR-likeCL0020TPRPF13414.1TPR_11TPR repeatK09523DNAJC3; DnaJ homolog subfamily C member 3--GO:0004860GO:0031072GO:0051082ALHF_00357.g1821581KA649918hypothetical proteinssp2-PAFBgn0036389NONAnot annotatedNONANONA----------------ALHF_00359.g1831407KA644551Abl-interactor HHRAbi-PCFBgn0020510RegulationSignal transduction50044SH3-domain\N\NPF07815.9Abi_HHRAbl-interactor HHR------GO:0004871GO:0005515ALHF_00361.g1841191KA644552NLI interacting factor-like phosphatasettm50-PAFBgn0250874MetabolismOther enzymes56784HAD-likeCL0137HADPF03031.13NIFNLI interacting factor-like phosphatase------GO:0003674ALHF_00362.g1852181KA644553FAD dependent oxidoreductaseGpo-1-PDFBgn0022160GeneralSmall molecule binding51905FAD/NAD(P)-binding domainCL0063NADP_RossmannPF01266.19DAOFAD dependent oxidoreductaseK00111glpA, glpD; glycerol-3-phosphate dehydrogenase[EC:1.1.5.3]GO:0004368GO:0005509ALHF_00363.g186312KA644554Core histone H2A/H2B/H3/H4CG33897-PAFBgn0053897RegulationDNA-binding47113Histone-foldCL0012HistonePF00125.19HistoneCore histone H2A/H2B/H3/H4K11254H4; histone H4--GO:0003677ALHF_00364.g1871158KA644555Serine carboxypeptidase S28CG2493-PAFBgn0032864MetabolismOther enzymes53474alpha/beta-HydrolasesCL0028AB_hydrolasePF05577.7Peptidase_S28Serine carboxypeptidase S28K01285PRCP; lysosomal Pro-X carboxypeptidase[EC:3.4.16.2]GO:0004185ALHF_00366.g188846KA649919SEA domain protein----NONAnot annotatedNONANONA\N\NPF01390.15SEASEA domain------ALHF_00367.g1891179KA644556ThiolaseCG9149-PAFBgn0035203MetabolismOther enzymes53901Thiolase-likeCL0046ThiolasePF00108.18Thiolase_NThiolase, N-terminal domainK00626E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase[EC:2.3.1.9]GO:0003985ALHF_00372.g1901806KA644557Zinc-finger of C2H2 typekey-PAFBgn0041205NONAnot annotatedNONANONACL0361C2H2-zfPF12874.2zf-metZinc-finger of C2H2 type------GO:0005515GO:0008270GO:0008384ALHF_00373.g1911530KA644558FibrinogenCG10359-PEFBgn0035452Extra-cellular processesBlood clotting56496Fibrinogen C-terminal domain-likeCL0422Fibrinogen_CPF00147.13Fibrinogen_CFibrinogen beta and gamma chains, C-terminal globular domain------GO:0005102ALHF_00374.g192825KA644559AsparaginaseCG7860-PAFBgn0030653MetabolismOther enzymes56235N-terminal nucleophile aminohydrolases (Ntn hydrolases)CL0052NTNPF01112.13Asparaginase_2AsparaginaseK13051iaaA, ASRGL1; beta-aspartyl-peptidase (threonine type)[EC:3.4.19.5]GO:0004067ALHF_00375.g193585KA644560Ribosomal protein S4/S9RpS9-PDFBgn0010408RegulationRNA binding, m/tr55174Alpha-L RNA-binding motif\N\NPF00163.14Ribosomal_S4Ribosomal protein S4/S9 N-terminal domainK02997RP-S9e, RPS9; small subunit ribosomal protein S9e--GO:0003735GO:0019843ALHF_00376.g1941203KA644561DnaJ domain proteinDroj2-PEFBgn0038145Intra-cellular processesProtein modification46565Chaperone J-domainCL0392Chaperone-JPF00226.26DnaJDnaJ domainK09502DNAJA1; DnaJ homolog subfamily A member 1--GO:0005524GO:0031072GO:0051082ALHF_00377.g195756KA644562Major intrinsic proteinDrip-PBFBgn0015872Intra-cellular processesTransport81338Aquaporin-like\N\NPF00230.15MIPMajor intrinsic proteinK09884AQPN; aquaporin rerated protein, invertebrate--GO:0005372GO:0015250ALHF_00378.g196423KA644563NinjurinCG14394-PCFBgn0038079NONAnot annotatedNONANONA\N\NPF04923.7NinjurinNinjurin------ALHF_00379.g1971113KA644564short chain dehydrogenaseCG17121-PAFBgn0039043GeneralSmall molecule binding51735NAD(P)-binding Rossmann-fold domainsCL0063NADP_RossmannPF00106.20adh_shortshort chain dehydrogenase------GO:0000166GO:0016616ALHF_00380.g1984509KA644565protein kinaseMekk1-PCFBgn0024329RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF00069.20PkinaseProtein kinase domain------GO:0004702GO:0004709GO:0005524GO:0031434ALHF_00383.g1991134KA644566Ecdysteroid kinaseCG9497-PAFBgn0031800RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF02958.15EcKinaseEcdysteroid kinase------GO:0016772ALHF_00384.g200339KA644567HMG (high mobility group) boxHmgZ-PAFBgn0010228RegulationDNA-binding47095HMG-boxCL0114HMG-boxPF00505.14HMG_boxHMG (high mobility group) box------GO:0003677ALHF_00385.g2011608KA644568Cytochrome P450Cyp12c1-PAFBgn0036806MetabolismRedox48264Cytochrome P450\N\NPF00067.17p450Cytochrome P450K15004CYP12; cytochrome P450, family 12[EC:1.14.-.-]GO:0009055GO:0016705GO:0020037ALHF_00386.g202411KA649920hypothetical proteinCG42245-PAFBgn0250911NONAnot annotatedNONANONA\N\NPF11242.3DUF2774Protein of unknown function (DUF2774)------ALHF_00388.g2031438KA649921hypothetical proteinCG34398-PJFBgn0085427NONAnot annotatedNONANONA----------------ALHF_00389.g204684KA644569hypothetical proteinCG10205-PAFBgn0033970NONAnot annotatedNONANONACL0255ATP_synthasePF02108.11FliHFlagellar assembly protein FliH------GO:0003674ALHF_00391.g205483KA644570SRP19 proteinSrp19-PAFBgn0015298Intra-cellular processesTransport69695SRP19\N\NPF01922.12SRP19SRP19 proteinK03105SRP19; signal recognition particle subunit SRP19--GO:0008312ALHF_00396.g206675KA644571GrpERoe1-PAFBgn0014877GeneralProtein interaction58014Coiled-coil domain of nucleotide exchange factor GrpE\N\NPF01025.14GrpEGrpEK03687GRPE; molecular chaperone GrpE--GO:0000774GO:0042803GO:0051082GO:0051087ALHF_00397.g207510KA644572ThioredoxinCG3719-PAFBgn0024986MetabolismRedox52833Thioredoxin-likeCL0172ThioredoxinPF00085.15ThioredoxinThioredoxin------GO:0009055GO:0015035GO:0015036ALHF_00398.g2081596KA644573haloacid dehalogenase-like hydrolaseCG32000-PHFBgn0052000Intra-cellular processesIon m/tr81665Calcium ATPase, transmembrane domain MCL0137HADPF12710.2HADhaloacid dehalogenase-like hydrolaseK14951ATP13A3_4_5; cation-transporting ATPase 13A3/4/5[EC:3.6.3.-]GO:0005524GO:0015662GO:0042625GO:0046872ALHF_00399.g2091269KA644574hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00402.g2111054KA649922hepatic protein Spot 14gpp-PEFBgn0261972NONAnot annotatedNONANONA\N\NPF07084.7Spot_14Thyroid hormone-inducible hepatic protein Spot 14K11427DOT1L, DOT1; histone-lysine N-methyltransferase, H3 lysine-79 specific[EC:2.1.1.43]GO:0031151ALHF_00405.g2121449KA644575UTPHypotheticalglucose-1-phosphate uridylyltransferasemmy-PBFBgn0259749MetabolismTransferases53448Nucleotide-diphospho-sugar transferasesCL0110GT-APF01704.13UDPGPUTP--glucose-1-phosphate uridylyltransferaseK00972UAP1; UDP-N-acetylglucosamine pyrophosphorylase[EC:2.7.7.23]GO:0003977ALHF_00408.g213537KA644576ATP synthase D chain, mitochondrialATPsyn-d-PAFBgn0016120NONAnot annotatedNONANONA\N\NPF05873.7Mt_ATP-synt_DATP synthase D chain, mitochondrial (ATP5H)K02138ATPeFD, ATP5H; F-type H+-transporting ATPase subunit d[EC:3.6.3.14]GO:0008553ALHF_00409.g2141114KA649923EphrinEphrin-PDFBgn0040324Intra-cellular processesIon m/tr49503CupredoxinsCL0026CU_oxidasePF00812.12EphrinEphrinK05463EFNB; ephrin-B--GO:0046875ALHF_00410.g215426KA649924pfkB family carbohydrate kinaseCG11255-PBFBgn0036337MetabolismOther enzymes53613Ribokinase-likeCL0118RibokinasePF00294.19PfkBpfkB family carbohydrate kinaseK00856E2.7.1.20, ADK; adenosine kinase[EC:2.7.1.20]GO:0004001GO:0016773ALHF_00411.g2161476KA644577Ankyrin repeat proteincact-PDFBgn0004198RegulationDNA-binding47413lambda repressor-like DNA-binding domainsCL0465AnkPF00023.25AnkAnkyrin repeatK09259K09259; ankyrin only family, other--GO:0000976GO:0003677GO:0003700ALHF_00412.g2171476KA644578Ankyrin repeat proteincact-PDFBgn0004198RegulationDNA-binding47413lambda repressor-like DNA-binding domainsCL0465AnkPF00023.25AnkAnkyrin repeatK09259K09259; ankyrin only family, other--ALHF_00413.g2181458KA644579Flavin containing amine oxidoreductaseCG7460-PBFBgn0036749GeneralSmall molecule binding51905FAD/NAD(P)-binding domainCL0063NADP_RossmannPF01593.19Amino_oxidaseFlavin containing amine oxidoreductase------GO:0016491ALHF_00416.g219381KA644580pheromone-binding family, A10/OS-DPebIII-PAFBgn0011695RegulationReceptor activity100910Chemosensory protein Csp2\N\NPF03392.8OS-DInsect pheromone-binding family, A10/OS-D------ALHF_00417.g2201260KA644581Aminotransferase class 1 and 2CG6950-PDFBgn0037955MetabolismTransferases53383PLP-dependent transferasesCL0061PLP_aminotranPF00155.16Aminotran_1_2Aminotransferase class I and IIK00816CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase[EC:2.6.1.74.4.1.132.6.1.64]GO:0016212GO:0016847GO:0030170ALHF_00419.g221894KA644582hypothetical proteinCG3884-PCFBgn0033786NONAnot annotatedNONANONA\N\NPF11901.3DUF3421Protein of unknown function (DUF3421)------ALHF_00420.g2221461KA644583Leucine Rich repeat proteinCG15412-PBFBgn0031528Extra-cellular processesCell adhesion52047RNI-likeCL0022LRRPF13516.1LRR_6Leucine Rich repeat------ALHF_00421.g2232652KA644584Tetratricopeptide repeat proteinCG6197-PAFBgn0033859GeneralProtein interaction48452TPR-likeCL0020TPRPF13428.1TPR_14Tetratricopeptide repeatK12867SYF1, XAB2; pre-mRNA-splicing factor SYF1--GO:0005488ALHF_00422.g2242463KA644585PWI domain proteinCG4119-PAFBgn0028474RegulationRNA binding, m/tr54928RNA-binding domain, RBD\N\NPF01480.12PWIPWI domainK12822RBM25, S164; RNA-binding protein 25--GO:0000166GO:0003676GO:0003729ALHF_00430.g225336KA644586Tctex-1 family proteinDlc90F-PAFBgn0024432NONAnot annotatedNONANONA\N\NPF03645.8Tctex-1Tctex-1 familyK10420DYNLT; dynein light chain Tctex-type 1--GO:0042623GO:0042803GO:0045505ALHF_00431.g226450KA644587KOW motif proteinRpL26-PAFBgn0036825InformationTranslation50104Translation proteins SH3-like domainCL0107KOWPF00467.24KOWKOW motifK02898RP-L26e, RPL26; large subunit ribosomal protein L26e--GO:0003735ALHF_00432.g2271266KA644588hypothetical proteinCG16884-PAFBgn0028544NONAnot annotatedNONANONA----------------ALHF_00433.g2282061KA644589Eukaryotic translation initiation factor eIF2AeIF3-S9-PAFBgn0034237Intra-cellular processesProteases82171DPP6 N-terminal domain-likeCL0186Beta_propellerPF08662.6eIF2AEukaryotic translation initiation factor eIF2AK03253EIF3B; translation initiation factor 3 subunit B--GO:0000166GO:0003729GO:0003743ALHF_00434.g229582KA644590ADP-ribosylation factor familysar1-PEFBgn0038947GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00025.16ArfADP-ribosylation factor familyK07953SAR1; GTP-binding protein SAR1[EC:3.6.5.-]GO:0003924GO:0005525ALHF_00435.g230771KA644591hypothetical protein14-3-3epsilon-PCFBgn0020238GeneralProtein interaction4844514-3-3 protein\N\NPF00244.1514-3-314-3-3 proteinK06630YWHA; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein--GO:0008426GO:0019904GO:0046982ALHF_00439.g2321164KA644592Golgi 4-transmembrane spanning transporterCG14767-PBFBgn0040777NONAnot annotatedNONANONA\N\NPF03821.11MtpGolgi 4-transmembrane spanning transporterK12387LAPTM; lysosomal-associated transmembrane protein--GO:0015205ALHF_00443.g2335805KA644593Nuclear protein 96Nup98-PAFBgn0039120Intra-cellular processesTransport82215C-terminal autoproteolytic domain of nucleoporin nup98\N\NPF12110.3Nup96Nuclear protein 96K14297NUP98, ADAR2; nuclear pore complex protein Nup98-Nup96--ALHF_00444.g234756KA644594Hemolymph juvenile hormone binding protein (JHBP)CG5867-PAFBgn0027586NONAnot annotatedNONANONA\N\NPF06585.6JHBPHaemolymph juvenile hormone binding protein (JHBP)------ALHF_00445.g2351098KA644595Spermine/spermidine synthaseCG4300-PBFBgn0036272MetabolismTransferases53335S-adenosyl-L-methionine-dependent methyltransferasesCL0063NADP_RossmannPF01564.12Spermine_synthSpermine/spermidine synthaseK00802SMS; spermine synthase[EC:2.5.1.22]GO:0004766GO:0016768ALHF_00446.g2361335KA644596Transmembrane amino acid transporter proteinCG4991-PCFBgn0030817NONAnot annotatedNONANONACL0062APCPF01490.13Aa_transTransmembrane amino acid transporter proteinK14209SLC36A, PAT; solute carrier family 36 (proton-coupled amino acid transporter)--GO:0015171ALHF_00449.g2371011KA644597BSD domain proteinSap47-PFFBgn0013334OtherUnknown function140383BSD domain-like\N\NPF03909.12BSDBSD domain------GO:0003674ALHF_00449.g2382181KA644598HSF-type DNA-binding proteinHsf-PAFBgn0001222RegulationDNA-binding46785Winged helix DNA-binding domainCL0123HTHPF00447.12HSF_DNA-bindHSF-type DNA-bindingK09418HSFN; heat shock transcription factor, invertebrate--GO:0003677GO:0003700GO:0005515GO:0043565ALHF_00451.g2391500KA644599CD36 family proteinCG2736-PAFBgn0035090NONAnot annotatedNONANONA\N\NPF01130.16CD36CD36 family------GO:0005044ALHF_00454.g240819KA644600TrypsinCG11912-PAFBgn0031248Intra-cellular processesProteases50494Trypsin-like serine proteasesCL0124Peptidase_PAPF00089.21TrypsinTrypsin------GO:0004252ALHF_00455.g2413687KA644601JNK SAPK-associated protein-1syd-PAFBgn0024187MetabolismOther enzymes50969YVTN repeat-like/Quinoprotein amine dehydrogenase\N\NPF09744.4Jnk-SapK_ap_NJNK_SAPK-associated protein-1------GO:0019894ALHF_00457.g242540KA644602ETC complex I subunit conserved regionCG12203-PAFBgn0031021NONAnot annotatedNONANONA\N\NPF04800.7ETC_C1_NDUFA4ETC complex I subunit conserved regionK03937NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4[EC:1.6.5.31.6.99.3]GO:0008137ALHF_00459.g243651KA644603PhosducinCG4511-PBFBgn0037843MetabolismRedox52833Thioredoxin-likeCL0172ThioredoxinPF02114.11PhosducinPhosducin------GO:0005524ALHF_00460.g244657KA644604Lipocalin-like proteinCG14872-PAFBgn0038346Intra-cellular processesTransport50814LipocalinsCL0116CalycinPF08212.7Lipocalin_2Lipocalin-like domain------GO:0005488ALHF_00461.g245606KA644605Dynactin subunitl(2)06496-PAFBgn0010622NONAnot annotatedNONANONA\N\NPF07426.6Dynactin_p22Dynactin subunit p22K10425DCTN3; dynactin 3--ALHF_00462.g24611223KA644606Laminin EGF-like proteinLanA-PAFBgn0002526MetabolismSecondary metabolism49899Concanavalin A-like lectins/glucanasesCL0001EGFPF00053.19Laminin_EGFLaminin EGF-like (Domains III and V)K06240LAMA3_5; laminin, alpha 3/5--GO:0005102ALHF_00463.g2473045KA644607Muniscin mu-like domain proteinCG8176-PAFBgn0037702GeneralProtein interaction103657BAR/IMD domain-likeCL0448Cargo_bd_muHDPF10291.4muHDMuniscin C-terminal mu homology domain------ALHF_00466.g2481842KA644608Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain 1Pmm45A-PAFBgn0033377MetabolismCarbohydrate m/tr53738Phosphoglucomutase, first 3 domains\N\NPF02878.11PGM_PMM_IPhosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain IK01835pgm; phosphoglucomutase[EC:5.4.2.2]GO:0000287GO:0004615ALHF_00467.g249822KA644609CRAL/TRIO domain proteinCG3191-PAFBgn0023525Intra-cellular processesPhospholipid m/tr52087CRAL/TRIO domainCL0512CRAL_TRIOPF00650.15CRAL_TRIOCRAL/TRIO domain------GO:0005215ALHF_00468.g250822KA644610Septum formation initiator----NONAnot annotatedNONANONACL0225FtsLPF04977.10DivICSeptum formation initiator------ALHF_00470.g251672KA644611Ferritin-like proteinFer2LCH-PCFBgn0015221Intra-cellular processesIon m/tr47240Ferritin-likeCL0044FerritinPF00210.19FerritinFerritin-like domain------GO:0008198GO:0008199GO:0016491ALHF_00471.g252336KA644612Rhodanese-like proteinCG12279-PAFBgn0038080Intra-cellular processesCell cycle, Apoptosis52821Rhodanese/Cell cycle control phosphatase\N\NPF00581.15RhodaneseRhodanese-like domainK01011TST, MPST, sseA; thiosulfate/3-mercaptopyruvate sulfurtransferase[EC:2.8.1.12.8.1.2]GO:0004792GO:0051082ALHF_00472.g253996KA644613TatD related DNaseCG3308-PAFBgn0038877MetabolismOther enzymes51556Metallo-dependent hydrolasesCL0034AmidohydrolasePF01026.16TatD_DNaseTatD related DNaseK03424tatD; TatD DNase family protein[EC:3.1.21.-]GO:0004536GO:0016888ALHF_00473.g254561KA644614RedoxinPrx5-PBFBgn0038570MetabolismRedox52833Thioredoxin-likeCL0172ThioredoxinPF08534.5RedoxinRedoxinK11187PRDX5; peroxiredoxin 5, atypical 2-Cys peroxiredoxin[EC:1.11.1.15]GO:0016209GO:0016491ALHF_00474.g2553240KA644615CCR4-Not complex component, Not1Not1-PGFBgn0085436NONAnot annotatedNONANONA\N\NPF04054.10Not1CCR4-Not complex component, Not1K12604CNOT1, NOT1; CCR4-NOT transcription complex subunit 1--ALHF_00475.g2563246KA644616CCR4-Not complex component, Not1Not1-PGFBgn0085436NONAnot annotatedNONANONA\N\NPF04054.10Not1CCR4-Not complex component, Not1K12604CNOT1, NOT1; CCR4-NOT transcription complex subunit 1--ALHF_00476.g257825KA644617Trehalose-phosphataseCG5177-PAFBgn0031908MetabolismOther enzymes56784HAD-likeCL0137HADPF02358.11Trehalose_PPaseTrehalose-phosphataseK01087otsB; trehalose 6-phosphate phosphatase[EC:3.1.3.12]GO:0004805ALHF_00479.g2591146KA644618RNA recognition proteinHrb87F-PCFBgn0004237RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF00076.17RRM_1RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)K12741HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3--GO:0000166GO:0003729GO:0043565ALHF_00480.g2601128KA644619Double-stranded RNA binding motif proteinloqs-PAFBgn0032515RegulationRNA binding, m/tr54768dsRNA-binding domain-likeCL0196DSRMPF00035.20dsrmDouble-stranded RNA binding motif------GO:0003725GO:0005515ALHF_00481.g2611209KA644620DEAD/DEAH box helicaseeIF-4a-PEFBgn0001942GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00270.24DEADDEAD/DEAH box helicaseK03257EIF4A; translation initiation factor 4A--GO:0000339GO:0003724GO:0003729GO:0003743GO:0005524GO:0008026GO:0017116ALHF_00483.g2621230KA644621Isocitrate/isopropylmalate dehydrogenaseIdh-PJFBgn0001248MetabolismRedox53659Isocitrate/Isopropylmalate dehydrogenase-likeCL0270Iso_DHPF00180.15Iso_dhIsocitrate/isopropylmalate dehydrogenaseK00031IDH1, IDH2, icd; isocitrate dehydrogenase[EC:1.1.1.42]GO:0000287GO:0004450GO:0051287ALHF_00486.g2632634KA644622Synaptobrevintomosyn-PIFBgn0030412GeneralGeneral50978WD40 repeat-likeCL0445SNARE-fusionPF00957.16SynaptobrevinSynaptobrevinK08518STXBP5; syntaxin-binding protein 5--GO:0017075ALHF_00487.g2642190KA644623Regulator of G protein signaling proteinloco-PFFBgn0020278RegulationSignal transduction48097Regulator of G-protein signaling, RGSCL0272RGSPF00615.14RGSRegulator of G protein signaling domain------GO:0001965GO:0005057GO:0005096ALHF_00489.g2651845KA644624Signal recognition particle, alpha subunitGtp-bp-PAFBgn0086679Intra-cellular processesProteases69322Tricorn protease domain 2\N\NPF04086.8SRP-alpha_NSignal recognition particle, alpha subunit, N-terminalK13431SRPR; signal recognition particle receptor subunit alpha--GO:0003674ALHF_00491.g2673189KA644625RhoGAP domain proteinGraf-PCFBgn0030685GeneralProtein interaction103657BAR/IMD domain-likeCL0409GAPPF00620.22RhoGAPRhoGAP domain------GO:0005100GO:0005543ALHF_00492.g2682307KA644626Integrin, beta chainmys-PAFBgn0004657Extra-cellular processesCell adhesion53300vWA-like\N\NPF00362.13Integrin_betaIntegrin, beta chainK05719ITGB1; integrin beta 1--GO:0004872GO:0050839ALHF_00493.g2691362KA644627Adenylosuccinate synthetaseCG17273-PAFBgn0027493GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00709.16Adenylsucc_syntAdenylosuccinate synthetaseK01939E6.3.4.4, purA; adenylosuccinate synthase[EC:6.3.4.4]GO:0000287GO:0004019GO:0005525ALHF_00494.g2701212KA644628hypothetical proteinCG17002-PBFBgn0033122NONAnot annotatedNONANONA\N\NPF11853.3DUF3373Protein of unknown function (DUF3373)K15307GPS2; G protein pathway suppressor 2--ALHF_00494.g2713999KA644629ABC transporterMdr49-PAFBgn0004512GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0241ABC_membranePF00664.18ABC_membraneABC transporter transmembrane region------GO:0005524GO:0015238GO:0042623GO:0042626ALHF_00498.g272615KA644630Proteasome subunitCG17331-PAFBgn0032596MetabolismOther enzymes56235N-terminal nucleophile aminohydrolases (Ntn hydrolases)CL0052NTNPF00227.21ProteasomeProteasome subunitK02734PSMB2; 20S proteasome subunit beta 4[EC:3.4.25.1]GO:0004175GO:0004298ALHF_00499.g2731503KA644631Alpha amylaseAmy-p-PAFBgn0086679Intra-cellular processesProteases69322Tricorn protease domain 2CL0058Glyco_hydro_timPF00128.19Alpha-amylaseAlpha amylase, catalytic domainK01176E3.2.1.1, amyA, malS; alpha-amylase[EC:3.2.1.1]ALHF_00501.g274591KA644632cuticle proteinCpr62Bc-PAFBgn0035281NONAnot annotatedNONANONA\N\NPF00379.18Chitin_bind_4Insect cuticle protein------GO:0005214ALHF_00502.g2751563KA644633Aldehyde dehydrogenaseCG17896-PBFBgn0023537MetabolismRedox53720ALDH-likeCL0099ALDH-likePF00171.17AldedhAldehyde dehydrogenase familyK00140mmsA, iolA, ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase[EC:1.2.1.181.2.1.27]GO:0004491ALHF_00503.g2761197KA644634putative coiled-coil protein (DUF2205)spn-F-PAFBgn0086362NONAnot annotatedNONANONA\N\NPF10224.4DUF2205Predicted coiled-coil protein (DUF2205)------GO:0008569ALHF_00506.g277609KA644635Ribosomal protein L19eRpL19-PBFBgn0002607InformationTranslation48140Ribosomal protein L19 (L19e)\N\NPF01280.15Ribosomal_L19eRibosomal protein L19eK02885RP-L19e, RPL19; large subunit ribosomal protein L19e--GO:0003735ALHF_00507.g278369KA644636FtsK/Spo3E familyCG10375-PBFBgn0039116Intra-cellular processesProtein modification46565Chaperone J-domainCL0023P-loop_NTPasePF01580.13FtsK_SpoIIIEFtsK/SpoIIIE familyK09528DNAJC8; DnaJ homolog subfamily C member 8--GO:0031072GO:0051082ALHF_00509.g279744KA644637Endoplasmic reticulum-based factor for assembly of V-ATPaseCG7071-PBFBgn0260467NONAnot annotatedNONANONA\N\NPF11712.3Vma12Endoplasmic reticulum-based factor for assembly of V-ATPase------ALHF_00510.g280513KA644638hypothetical protein----NONAnot annotatedNONANONA\N\NPF06679.7DUF1180Protein of unknown function (DUF1180)------ALHF_00511.g2811095KA644639MethyltransferaseArt1-PAFBgn0037834MetabolismTransferases53335S-adenosyl-L-methionine-dependent methyltransferasesCL0063NADP_RossmannPF13847.1Methyltransf_31Methyltransferase domainK11434PRMT1; protein arginine N-methyltransferase 1[EC:2.1.1.-]GO:0016274GO:0035241GO:0035242GO:0042054GO:0044020ALHF_00512.g2822685KA644640hypothetical proteinCG11526-PAFBgn0035437NONAnot annotatedNONANONA\N\NPF11882.3DUF3402Domain of unknown function (DUF3402)------GO:0003674ALHF_00514.g2831095KA644641hypothetical proteinCG5828-PAFBgn0031682NONAnot annotatedNONANONA\N\NPF01937.14DUF89Protein of unknown function DUF89K09680coaW; type II pantothenate kinase[EC:2.7.1.33]ALHF_00515.g2842649KA644642Gamma-glutamyltranspeptidaseCG4829-PEFBgn0030796MetabolismOther enzymes56235N-terminal nucleophile aminohydrolases (Ntn hydrolases)CL0052NTNPF01019.16G_glu_transpeptGamma-glutamyltranspeptidase------GO:0003810GO:0003840ALHF_00516.g2851317KA644643RanBP1 domain proteinRanBP3-PAFBgn0039110RegulationSignal transduction50729PH domain-likeCL0266PHPF00638.13Ran_BP1RanBP1 domainK15304RANBP3; Ran-binding protein 3--ALHF_00518.g286642KA644644DNA/RNA non-specific endonucleaseCG14120-PAFBgn0036321InformationDNA replication/repair54060His-Me finger endonucleasesCL0263His-Me_fingerPF01223.18Endonuclease_NSDNA/RNA non-specific endonuclease------GO:0003676GO:0016787GO:0046872ALHF_00519.g287567KA644645Hsp20/alpha crystallin familyl(2)efl-PAFBgn0011296Intra-cellular processesProtein modification49764HSP20-like chaperonesCL0190HSP20PF00011.16HSP20Hsp20/alpha crystallin familyK09542CRYAB; crystallin, alpha B--ALHF_00521.g288465KA644646EF hand proteinMlc1-PBFBgn0002772GeneralGeneral47473EF-handCL0220EF_handPF13499.1EF_hand_5EF-hand domain pair------GO:0000146GO:0005509GO:0042623ALHF_00522.g289462KA644647EF hand proteinMlc1-PAFBgn0002772GeneralGeneral47473EF-handCL0220EF_handPF13499.1EF_hand_5EF-hand domain pair------ALHF_00523.g2906036KA644648hypothetical proteinmbc-PBFBgn0015513RegulationSignal transduction50044SH3-domainCL0154C2PF14429.1DOCK-C2C2 domain in Dock180 and Zizimin proteinsK05727DOCK3_4_5; dedicator of cytokinesis 3/4/5--GO:0005085GO:0005515GO:0005525GO:0051020ALHF_00524.g2911069KA649925Alpha and gamma adaptin binding protein----NONAnot annotatedNONANONA\N\NPF10199.4Adaptin_bindingAlpha and gamma adaptin binding protein p34------ALHF_00525.g292819KA644649hypothetical proteineIF-2beta-PAFBgn0004926InformationTranslation100966Translation initiation factor 2 beta, aIF2beta, N-terminal domain\N\NPF01873.12eIF-5_eIF-2BDomain found in IF2B/IF5K03238EIF2S2; translation initiation factor 2 subunit 2--GO:0000049GO:0003743GO:0005525ALHF_00527.g293450KA644650Ribosomal protein L18e/L15RpL27A-PAFBgn0261606InformationTranslation52080Ribosomal proteins L15p and L18e\N\NPF00828.14Ribosomal_L18eRibosomal protein L18e/L15K02900RP-L27Ae, RPL27A; large subunit ribosomal protein L27Ae--GO:0003735ALHF_00528.g294777KA644651alpha/beta hydrolaseCG2772-PAFBgn0031533MetabolismOther enzymes53474alpha/beta-HydrolasesCL0028AB_hydrolasePF00561.15Abhydrolase_1alpha/beta hydrolase fold------GO:0004806ALHF_00530.g2952043KA644652Subtilase family proteinamon-PAFBgn0023179Intra-cellular processesProteases52743Subtilisin-like\N\NPF00082.17Peptidase_S8Subtilase familyK01360PCSK2; proprotein convertase subtilisin/kexin type 2[EC:3.4.21.94]GO:0004252GO:0008233ALHF_00531.g2961386KA644653DEAD/DEAH box helicaseDbp80-PBFBgn0024804GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00270.24DEADDEAD/DEAH box helicase------GO:0003676GO:0004004GO:0005524GO:0008026ALHF_00532.g297630KA644654RWD domain proteinCG10343-PAFBgn0032703Intra-cellular processesProtein modification54495UBC-likeCL0208UBCPF05773.17RWDRWD domain------ALHF_00533.g298606KA644655Ubiquinone biosynthesis protein COQ7COQ7-PAFBgn0029502Intra-cellular processesIon m/tr47240Ferritin-likeCL0044FerritinPF03232.8COQ7Ubiquinone biosynthesis protein COQ7K06134COQ7; ubiquinone biosynthesis monooxygenase Coq7[EC:1.14.13.-]GO:0016491GO:0046914ALHF_00534.g2994272KA644656MyTH4 domain proteinMyo10A-PDFBgn0263705NONAnot annotatedNONANONA\N\NPF00784.12MyTH4MyTH4 domainK10361MYO15; myosin XV--GO:0003774GO:0005515GO:0005524GO:0042623ALHF_00535.g300636KA644657Ribosomal protein L13eRpL13-PBFBgn0011272NONAnot annotatedNONANONA\N\NPF01294.13Ribosomal_L13eRibosomal protein L13eK02873RP-L13e, RPL13; large subunit ribosomal protein L13e--GO:0003735ALHF_00537.g3011332KA644658Glycosyl hydrolaseCht8-PAFBgn0034580MetabolismCarbohydrate m/tr51445(Trans)glycosidasesCL0058Glyco_hydro_timPF00704.23Glyco_hydro_18Glycosyl hydrolases family 18K01183E3.2.1.14; chitinase[EC:3.2.1.14]GO:0004568GO:0008061GO:0043169ALHF_00538.g302555KA644659Ubiquitin-conjugating enzymeCG8188-PBFBgn0030863Intra-cellular processesProtein modification54495UBC-likeCL0208UBCPF00179.21UQ_conUbiquitin-conjugating enzymeK10583UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S[EC:6.3.2.19]GO:0004842ALHF_00539.g3031789KA649926PDZ domain proteinpyd-PJFBgn0262614NONAnot annotatedNONANONACL0466PDZ-likePF00595.19PDZPDZ domain (Also known as DHR or GLGF)K00942E2.7.4.8, gmk; guanylate kinase[EC:2.7.4.8]ALHF_00540.g3043309KA644660Formin-like proteinCG32138-PCFBgn0052138GeneralGeneral48371ARM repeat\N\NPF02181.18FH2Formin Homology 2 Domain------GO:0003779GO:0017048ALHF_00542.g3051269KA644661Glycosyl hydrolaseGNBP3-PAFBgn0040321MetabolismSecondary metabolism49899Concanavalin A-like lectins/glucanasesCL0004ConcanavalinPF00722.16Glyco_hydro_16Glycosyl hydrolases family 16------GO:0004553GO:0008329GO:0051636ALHF_00544.g3062139KA644662Leucine Rich repeat proteinwdp-PBFBgn0034718GeneralGeneral52058L domain-likeCL0022LRRPF12799.2LRR_4Leucine Rich repeats (2 copies)------ALHF_00548.g308558KA644663hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00549.g3092214KA644664hypothetical proteinCG7384-PAFBgn0032262NONAnot annotatedNONANONA\N\NPF04087.9DUF389Domain of unknown function (DUF389)------ALHF_00550.g310924KA644665NUDE proteinnudE-PBFBgn0036059NONAnot annotatedNONANONA\N\NPF04880.8NUDE_CNUDE protein, C-terminal conserved region------GO:0008017ALHF_00551.g311957KA644666Oxidoreductase FAD-binding proteinCG5946-PFFBgn0036211MetabolismRedox52343Ferredoxin reductase-like, C-terminal NADP-linked domainCL0076FAD_Lum_bindingPF00970.19FAD_binding_6Oxidoreductase FAD-binding domainK00326E1.6.2.2; cytochrome-b5 reductase[EC:1.6.2.2]GO:0004128ALHF_00553.g3122022KA644667Heme NO binding associatedGycalpha99B-PAFBgn0013972RegulationSignal transduction55073Nucleotide cyclase\N\NPF07701.9HNOBAHeme NO binding associatedK12318GUCY1A; guanylate cyclase soluble subunit alpha[EC:4.6.1.2]GO:0004383GO:0020037ALHF_00554.g3131491KA644668WD domain proteintws-PFFBgn0004889GeneralGeneral50978WD40 repeat-likeCL0186Beta_propellerPF00400.27WD40WD domain, G-beta repeatK04354PPP2R2; protein phosphatase 2 (formerly 2A), regulatory subunit B--GO:0004722GO:0008601ALHF_00555.g3141335KA649927Arsenite-resistance protein 2Ars2-PAFBgn0033062NONAnot annotatedNONANONA\N\NPF04959.8ARS2Arsenite-resistance protein 2------ALHF_00556.g3151257KA644669Double-stranded RNA binding motif proteinloqs-PBFBgn0032515RegulationRNA binding, m/tr54768dsRNA-binding domain-likeCL0196DSRMPF00035.20dsrmDouble-stranded RNA binding motif------ALHF_00557.g3166321KA644670Ion transport proteinpara-PDFBgn0260993Intra-cellular processesIon m/tr81324Voltage-gated potassium channelsCL0030Ion_channelPF00520.26Ion_transIon transport proteinK05388SCNAN; voltage-gated sodium channel alpha, invertebrate--ALHF_00558.g3171308KA644671Elongation factor TuEfTuM-PBFBgn0024556GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00009.22GTP_EFTUElongation factor Tu GTP binding domainK02358tuf, TUFM; elongation factor Tu--GO:0003746GO:0003924GO:0005525ALHF_00559.g3181131KA644672UbiquitinCG3223-PAFBgn0037538GeneralProtein interaction46934UBA-likeCL0072UbiquitinPF00240.18ubiquitinUbiquitin family------ALHF_00560.g3191008KA644673PAP2 superfamily proteinCG11426-PAFBgn0037166MetabolismRedox48317Acid phosphatase/Vanadium-dependent haloperoxidaseCL0525pap2PF01569.16PAP2PAP2 superfamilyK01080PPAP2; phosphatidate phosphatase[EC:3.1.3.4]GO:0008195ALHF_00563.g3201002KA644674hypothetical proteinjp-PEFBgn0032129InformationChromatin structure82185Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain----------------GO:0003674ALHF_00564.g321885KA644675WD domain proteinCiao1-PAFBgn0033972GeneralGeneral50978WD40 repeat-likeCL0186Beta_propellerPF00400.27WD40WD domain, G-beta repeat------GO:0003674ALHF_00565.g322411KA644676FAM92 protein----NONAnot annotatedNONANONACL0145Golgi-transportPF06730.6FAM92FAM92 protein------ALHF_00567.g3231248KA644677TrypsinCG5390-PAFBgn0032213Intra-cellular processesProteases50494Trypsin-like serine proteasesCL0124Peptidase_PAPF00089.21TrypsinTrypsin------GO:0004252ALHF_00569.g3241653KA644678Adenosine/AMP deaminaseAdgf-A-PBFBgn0036752MetabolismOther enzymes51556Metallo-dependent hydrolasesCL0034AmidohydrolasePF00962.17A_deaminaseAdenosine/AMP deaminaseK01488E3.5.4.4, ADA, add; adenosine deaminase[EC:3.5.4.4]GO:0004000GO:0008083ALHF_00572.g3252178KA644679Groucho/TLEgro-PFFBgn0001139GeneralGeneral50978WD40 repeat-like\N\NPF03920.10TLE_NGroucho/TLE N-terminal Q-rich domainK04497GROUCHO; groucho--GO:0001106GO:0003677GO:0003714GO:0005515GO:0008134GO:0070491ALHF_00573.g326684KA644680Class 2 Aldolase and AdducinCG11134-PAFBgn0030518MetabolismOther enzymes53639AraD/HMP-PK domain-like\N\NPF00596.16Aldolase_IIClass II Aldolase and Adducin N-terminal domainK08964mtnB; methylthioribulose-1-phosphate dehydratase[EC:4.2.1.109]GO:0046872ALHF_00574.g3271437KA644681Tetratricopeptide repeat proteinCG8223-PBFBgn0037624GeneralProtein interaction48452TPR-likeCL0020TPRPF13424.1TPR_12Tetratricopeptide repeat------GO:0005488ALHF_00578.g3281425KA644682Respiratory-chain NADH dehydrogenase 51 Kd subunitCG9140-PAFBgn0031771GeneralProtein interaction142019Nqo1 FMN-binding domain-likeCL0105HybridPF01512.12Complex1_51KRespiratory-chain NADH dehydrogenase 51 Kd subunitK03942NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1[EC:1.6.5.31.6.99.3]GO:0003954GO:0008137GO:0010181GO:0051287GO:0051539ALHF_00587.g331750KA644683Leucine Rich repeat proteinCG31076-PBFBgn0051076NONAnot annotatedNONANONACL0022LRRPF12799.2LRR_4Leucine Rich repeats (2 copies)------ALHF_00591.g3321080KA644684cuticle proteinCG8927-PAFBgn0038405NONAnot annotatedNONANONA\N\NPF00379.18Chitin_bind_4Insect cuticle protein------GO:0042302ALHF_00594.g3333570KA644685protein kinasePkn-PBFBgn0020621RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF00069.20PkinaseProtein kinase domainK06071PKN; protein kinase N[EC:2.7.11.13]GO:0004672GO:0004674GO:0004697GO:0005524ALHF_00596.g3341356KA644686hypothetical proteinCG13252-PAFBgn0037016Extra-cellular processesCell adhesion57603FnI-like domainCL0451FnI-likePF00093.13VWCvon Willebrand factor type C domain------ALHF_00601.g3351701KA644687MYND finger proteinCG14590-PAFBgn0033061Intra-cellular processesIon m/tr82199SET domainCL0175TRASHPF01753.13zf-MYNDMYND finger------GO:0008270GO:0042826ALHF_00602.g336816KA644688Inhibitor of growth proteins histone-binding proteinCG9293-PBFBgn0032516InformationDNA replication/repair57903FYVE/PHD zinc finger\N\NPF12998.2INGInhibitor of growth proteins N-terminal histone-bindingK11345ING5; inhibitor of growth protein 5--GO:0008270ALHF_00604.g3371560KA644689Aminotransferase class-3CG11241-PBFBgn0037186MetabolismTransferases53383PLP-dependent transferasesCL0061PLP_aminotranPF00202.16Aminotran_3Aminotransferase class-IIIK00827AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase[EC:2.6.1.442.6.1.40]GO:0008453GO:0030170ALHF_00605.g338447KA644690hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00609.g3391074KA649928hypothetical proteinCG10650-PAFBgn0046302NONAnot annotatedNONANONA\N\NPF05444.7DUF753Protein of unknown function (DUF753)------ALHF_00610.g3403624KA644691Kinase associated domain 1 proteinCG42856-PCFBgn0262103NONAnot annotatedNONANONA\N\NPF02149.14KA1Kinase associated domain 1------GO:0004674GO:0005524ALHF_00613.g3411143KA644692FKBP-type peptidyl-prolyl cis-trans isomeraseFK506-bp1-PAFBgn0013269Intra-cellular processesProtein modification54534FKBP-like\N\NPF00254.23FKBP_CFKBP-type peptidyl-prolyl cis-trans isomeraseK14826FPR3_4; FK506-binding nuclear protein[EC:5.2.1.8]GO:0003755GO:0005515GO:0005528GO:0070594ALHF_00614.g3424713KA644693Plexin cytoplasmic proteinplexB-PBFBgn0025740Extra-cellular processesCell adhesion101912Sema domain\N\NPF08337.7Plexin_cytoplPlexin cytoplasmic RasGAP domainK06821PLXNB; plexin B--GO:0005515GO:0017154ALHF_00615.g3431545KA644694Myb-like proteinAda2b-PBFBgn0000153MetabolismTransferases53383PLP-dependent transferasesCL0123HTHPF00249.26Myb_DNA-bindingMyb-like DNA-binding domainK15127TADA2B; transcriptional adapter 2-beta--GO:0004068GO:0004351GO:0030170ALHF_00621.g3457464KA644695FAT domain proteinTor-PAFBgn0021796GeneralGeneral48371ARM repeatCL0020TPRPF02259.18FATFAT domainK07203FRAP; FKBP12-rapamycin complex-associated protein--GO:0004672GO:0016773GO:0043621ALHF_00624.g346768KA644696hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00625.g3471359KA644697Carboxylesteraseclt-PAFBgn0086367NONAnot annotatedNONANONACL0028AB_hydrolasePF00135.23COesteraseCarboxylesterase family------GO:0003832GO:0016787GO:0031964ALHF_00626.g3482838KA644698hypothetical proteinRanbp16-PFFBgn0053180GeneralGeneral48371ARM repeatCL0020TPRPF08767.6CRM1_CCRM1 C terminal------GO:0005049GO:0005488GO:0008536GO:0008565ALHF_00628.g3491320KA644699ATPase family associated proteinPros26.4-PAFBgn0015282GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00004.24AAAATPase family associated with various cellular activities (AAA)K03062PSMC1, RPT2; 26S proteasome regulatory subunit T2--GO:0004175GO:0005524GO:0016887ALHF_00629.g350462KA644700Copper/zinc superoxide dismutaseSod-PAFBgn0003462MetabolismRedox49329Cu,Zn superoxide dismutase-like\N\NPF00080.15Sod_CuCopper/zinc superoxide dismutase (SODC)K04565E1.15.1.1C, sodC, SOD1; Cu/Zn superoxide dismutase[EC:1.15.1.1]GO:0004784GO:0016209GO:0046872ALHF_00630.g35110149KA644701hypothetical proteinVps13-PBFBgn0033194NONAnot annotatedNONANONA\N\NPF06650.7DUF1162Protein of unknown function (DUF1162)------ALHF_00632.g3522178KA644702Peptidase family M13CG14526-PBFBgn0027578Intra-cellular processesProteases55486Metalloproteases ("zincins"), catalytic domain\N\NPF05649.8Peptidase_M13_NPeptidase family M13------GO:0004222ALHF_00633.g353942KA644703RNA ligase-like proteinCG12129-PAFBgn0033475InformationRNA processing54791Eukaryotic type KH-domain (KH-domain type I)CL02472HPF10469.4AKAP7_NLSAKAP7 2'5' RNA ligase-like domain------GO:0003723GO:0003824ALHF_00636.g3541455KA644704Glycosyl hydrolasealpha-Man-I-POFBgn0259170MetabolismCarbohydrate m/tr48225Seven-hairpin glycosidasesCL00596_HairpinPF01532.15Glyco_hydro_47Glycosyl hydrolase family 47K01230MAN1; mannosyl-oligosaccharide alpha-1,2-mannosidase[EC:3.2.1.113]GO:0004571GO:0005509ALHF_00638.g3551476KA644705hypothetical proteinSpn-PJFBgn0010905NONAnot annotatedNONANONACL0003SAMPF00536.25SAM_1SAM domain (Sterile alpha motif)------GO:0008157ALHF_00639.g356366KA644706Glutamine synthetaseGs2-PAFBgn0001145MetabolismAmino acids m/tr55931Glutamine synthetase/guanido kinaseCL0286GCSPF00120.19Gln-synt_CGlutamine synthetase, catalytic domainK01915glnA; glutamine synthetase[EC:6.3.1.2]GO:0004356ALHF_00640.g3571155KA644707Cdc37 Hsp90 binding domain proteinCdc37-PAFBgn0011573InformationTranslation101391Hsp90 co-chaperone CDC37\N\NPF08565.6CDC37_MCdc37 Hsp90 binding domainK09554CDC37; cell division cycle protein 37--GO:0019901GO:0030296GO:0051082GO:0051087ALHF_00644.g358510KA644708MAPEG familyCG33178-PAFBgn0053178NONAnot annotatedNONANONA\N\NPF01124.13MAPEGMAPEG family------ALHF_00646.g359399KA644709Hemolymph juvenile hormone binding protein (JHBP)CG17189-PAFBgn0039485NONAnot annotatedNONANONA\N\NPF06585.6JHBPHaemolymph juvenile hormone binding protein (JHBP)------ALHF_00647.g360333KA649929hypothetical proteinNpc1a-PDFBgn0024320Intra-cellular processesTransport82866Multidrug efflux transporter AcrB transmembrane domain----------K12385NPC1; Niemann-Pick C1 protein--GO:0008158ALHF_00648.g3611143KA644710protein kinasebsk-PEFBgn0000229RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF00069.20PkinaseProtein kinase domainK04440JNK; c-Jun N-terminal kinase[EC:2.7.11.24]GO:0004674GO:0004705GO:0004707GO:0005515GO:0005524ALHF_00649.g362726KA644711hypothetical proteinCG8675-PAFBgn0030834NONAnot annotatedNONANONA\N\NPF10217.4DUF2039Uncharacterized conserved protein (DUF2039)------ALHF_00653.g3641266KA644712Ecdysteroid kinaseCG13659-PAFBgn0039319RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF02958.15EcKinaseEcdysteroid kinase------GO:0016772ALHF_00654.g365828KA644713hypothetical proteinImpL2-PCFBgn0001257Extra-cellular processesCell adhesion48726ImmunoglobulinCL0011IgPF07679.11I-setImmunoglobulin I-set domain------ALHF_00656.g3661356KA644714DNA methyltransferase 1-associated protein 1 (DMAP1)DMAP1-PAFBgn0034537NONAnot annotatedNONANONA\N\NPF05499.7DMAP1DNA methyltransferase 1-associated protein 1 (DMAP1)K11324DMAP1, SWC4, EAF2; DNA methyltransferase 1-associated protein 1--GO:0003677ALHF_00657.g3671851KA644715FDF domain proteinEdc3-PBFBgn0036735NONAnot annotatedNONANONA\N\NPF09532.5FDFFDF domainK12615EDC3; enhancer of mRNA-decapping protein 3--ALHF_00658.g3682130KA644716Endonuclease/Exonuclease/phosphatase family proteinOcrl-PAFBgn0015374Intra-cellular processesProtein modification54495UBC-like\N\NPF03372.18Exo_endo_phosEndonuclease/Exonuclease/phosphatase family------GO:0004842ALHF_00659.g369738KA644717YhhN-like proteinCG7582-PAFBgn0039681NONAnot annotatedNONANONA\N\NPF07947.9YhhNYhhN-like protein------ALHF_00660.g370690KA649930Phosphatidylinositol transfer proteinrdgB-PHFBgn0003218GeneralGeneral55961Bet v1-likeCL0209Bet_V_1_likePF02121.13IP_transPhosphatidylinositol transfer protein------ALHF_00661.g3717224KA644718Beta-ketoacyl synthaseCG17374-PCFBgn0040001NONAnot annotatedNONANONACL0046ThiolasePF00109.21ketoacyl-syntBeta-ketoacyl synthase, N-terminal domainK00665FASN; fatty acid synthase, animal type[EC:2.3.1.85]GO:0000036GO:0000166GO:0004312GO:0008270GO:0016491GO:0016788GO:0048037ALHF_00666.g3722592KA644719exonucleaseRrp6-PBFBgn0038269MetabolismNucleotide m/tr53098Ribonuclease H-likeCL0219RNase_HPF01612.15DNA_pol_A_exo13'-5' exonucleaseK12591RRP6, EXOSC10; exosome complex exonuclease RRP6[EC:3.1.13.-]GO:0000166GO:0003676GO:0008408ALHF_00667.g3732028KA644720Sodium:neurotransmitter symporter family proteinCG43066-PAFBgn0262476NONAnot annotatedNONANONA\N\NPF00209.13SNFSodium:neurotransmitter symporter familyK05048SLC6A15S; solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20--GO:0005215GO:0005326GO:0005328ALHF_00676.g3751002KA644721lactate/malate dehydrogenaseMdh1-PAFBgn0262782MetabolismRedox56327LDH C-terminal domain-likeCL0341LDH_CPF02866.13Ldh_1_Clactate/malate dehydrogenase, alpha/beta C-terminal domainK00025MDH1; malate dehydrogenase[EC:1.1.1.37]GO:0000166GO:0030060ALHF_00678.g3762406KA644722Hsp90 proteinGp93-PAFBgn0039562InformationTranslation54211Ribosomal protein S5 domain 2-like\N\NPF00183.13HSP90Hsp90 proteinK09487HSP90B, TRA1; heat shock protein 90kDa beta--GO:0005524GO:0051082ALHF_00682.g378960KA644723SulfotransferaseCG5431-PBFBgn0034888GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00685.22Sulfotransfer_1Sulfotransferase domainK01018E2.8.2.9; tyrosine-ester sulfotransferase[EC:2.8.2.9]GO:0017067ALHF_00683.g379870KA644724High-temperature-induced dauer-formation proteinCG8155-PAFBgn0034009RegulationSignal transduction47923Ypt/Rab-GAP domain of gyp1pCL0456Golgi_traffPF12722.2Hid1High-temperature-induced dauer-formation protein------GO:0005097ALHF_00685.g3811797KA644725protein kinasesmi35A-PEFBgn0016930RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF00069.20PkinaseProtein kinase domainK08825DYRK; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase[EC:2.7.12.1]GO:0004672GO:0004674GO:0004713GO:0005524GO:0016740ALHF_00688.g382339KA644726hypothetical proteinCG13585-PDFBgn0035020NONAnot annotatedNONANONA\N\NPF11027.3DUF2615Protein of unknown function (DUF2615)------ALHF_00690.g3832182KA649931DnaJosp-PFFBgn0003016RegulationSignal transduction50729PH domain-likeCL0392Chaperone-JPF00226.26DnaJDnaJ domain------GO:0003674GO:0005543ALHF_00692.g384846KA644727SPFH domain / Band 7 family proteinFlo-2-PHFBgn0024753Intra-cellular processesIon m/tr117892Band 7/SPFH domainCL0433SPFHPF01145.20Band_7SPFH domain / Band 7 familyK07192FLOT; flotillin--ALHF_00694.g3851383KA644728Cytidylyltransferase familyCdsA-PAFBgn0010350NONAnot annotatedNONANONACL0234CTPTPF01148.15CTP_transf_1Cytidylyltransferase familyK00981E2.7.7.41, CDS1, cdsA; phosphatidate cytidylyltransferase[EC:2.7.7.41]GO:0004605ALHF_00700.g3871122KA644729hypothetical protein----NONAnot annotatedNONANONA\N\NPF04407.7DUF531Protein of unknown function (DUF531)------ALHF_00707.g3881851KA644730Initiation factor 2 subunit familyeIF2B-delta-PDFBgn0034858MetabolismTransferases100950NagB/RpiA/CoA transferase-likeCL0246ISOCOT_FoldPF01008.12IF-2BInitiation factor 2 subunit familyK03680EIF2B4; translation initiation factor eIF-2B subunit delta--GO:0003743ALHF_00712.g389543KA649932FibrinogenCG30281-PAFBgn0050281Extra-cellular processesBlood clotting56496Fibrinogen C-terminal domain-likeCL0422Fibrinogen_CPF00147.13Fibrinogen_CFibrinogen beta and gamma chains, C-terminal globular domain------ALHF_00714.g3901917KA644731hypothetical proteinCG12065-PFFBgn0030052MetabolismNucleotide m/tr53167Purine and uridine phosphorylases----------------GO:0003824ALHF_00719.g3911098KA644732Poly A polymeraseCG2100-PBFBgn0037369InformationTranscription81891Poly A polymerase C-terminal region-likeCL0260NTP_transfPF01743.15PolyA_polPoly A polymerase head domainK00974cca; tRNA nucleotidyltransferase (CCA-adding enzyme)[EC:2.7.7.723.1.3.-3.1.4.-]GO:0003723GO:0004652ALHF_00720.g3921422KA644733Leucine rich repeat proteinalrm-PAFBgn0039332GeneralGeneral52058L domain-likeCL0022LRRPF13855.1LRR_8Leucine rich repeat------ALHF_00723.g393754KA649933WW domain proteinyki-PFFBgn0034970GeneralProtein interaction51045WW domain\N\NPF00397.21WWWW domain------GO:0003713GO:0004842GO:0008134ALHF_00727.g3951686KA644734protein kinaseCG4839-PAFBgn0032187RegulationKinases/phosphatases56112Protein kinase-like (PK-like)CL0016PKinasePF00069.20PkinaseProtein kinase domainK07376PRKG; protein kinase, cGMP-dependent[EC:2.7.11.12]GO:0004674GO:0004692GO:0005524ALHF_00728.g3961062KA644735hypothetical protein----NONAnot annotatedNONANONA----no--annotation --------ALHF_00730.g397657KA644736hypothetical proteinCG11178-PBFBgn0030499NONAnot annotatedNONANONA----------------ALHF_00732.g3983735KA644737hypothetical proteinCG3764-PAFBgn0036684NONAnot annotatedNONANONA----------------ALHF_00733.g399891KA644738TetraspaninTsp86D-PBFBgn0037848Extra-cellular processesImmune response48652TetraspaninCL0347TetraspanninPF00335.15TetraspanninTetraspanin family------GO:0003674ALHF_00735.g400498KA644739FibrillarinFib-PAFBgn0003062MetabolismTransferases53335S-adenosyl-L-methionine-dependent methyltransferasesCL0063NADP_RossmannPF01269.12FibrillarinFibrillarinK14563NOP1, FBL; rRNA 2'-O-methyltransferase fibrillarin[EC:2.1.1.-]GO:0003729GO:0008168ALHF_00738.g401897KA644740Exosome complex exonuclease RRP4 regionRrp4-PAFBgn0034879InformationRNA processing54791Eukaryotic type KH-domain (KH-domain type I)\N\NPF14382.1ECR1_NExosome complex exonuclease RRP4 N-terminal regionK03679RRP4, EXOSC2; exosome complex component RRP4--GO:0000175ALHF_00740.g402705KA644741ASF1 like histone chaperoneasf1-PBFBgn0029094RegulationOther regulatory function101546ASF1-likeCL0463ASF1-likePF04729.8ASF1_hist_chapASF1 like histone chaperoneK10753ASF1; histone chaperone ASF1--GO:0005515ALHF_00742.g4031332KA644742WD domain proteintws-PHFBgn0004889GeneralGeneral50978WD40 repeat-likeCL0186Beta_propellerPF00400.27WD40WD domain, G-beta repeatK04354PPP2R2; protein phosphatase 2 (formerly 2A), regulatory subunit B--ALHF_00743.g4041626KA644743Zinc-finger proteinCG2116-PAFBgn0030003RegulationDNA-binding57667beta-beta-alpha zinc fingersCL0361C2H2-zfPF13465.1zf-H2C2_2Zinc-finger double domain------GO:0003676GO:0008270ALHF_00745.g4051362KA644744N-Acetylglucosaminyltransferase-4 (GnT-4) conserved regionCG9384-PAFBgn0036446NONAnot annotatedNONANONA\N\NPF04666.8Glyco_transf_54N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved regionK00738MGAT4A_B; alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B[EC:2.4.1.145]GO:0008454ALHF_00746.g4061530KA644745hypothetical proteinSP1029-PAFBgn0263236Intra-cellular processesProteases55486Metalloproteases ("zincins"), catalytic domain\N\NPF11838.3DUF3358Domain of unknown function (DUF3358)K11140ANPEP; aminopeptidase N[EC:3.4.11.2]GO:0004046GO:0004177GO:0008237GO:0008270ALHF_00747.g4071797KA644746hypothetical proteinpyd-PJFBgn0262614NONAnot annotatedNONANONA----------K00942E2.7.4.8, gmk; guanylate kinase[EC:2.7.4.8]GO:0004385GO:0050839ALHF_00748.g4084980KA644747hypothetical proteinCG13800-PAFBgn0035338NONAnot annotatedNONANONA----------------ALHF_00751.g4101920KA644748DNA-binding proteinmre11-PBFBgn0020270Intra-cellular processesProteases56300Metallo-dependent phosphatases\N\NPF04152.9Mre11_DNA_bindMre11 DNA-binding presumed domainK10865MRE11; double-strand break repair protein MRE11--GO:0004519GO:0004527GO:0030145ALHF_00752.g411531KA649934AnkyrinCG31919-PFFBgn0031674GeneralProtein interaction48403Ankyrin repeatCL0465AnkPF13637.1Ank_4Ankyrin repeats (many copies)------ALHF_00755.g4125634KA644749hypothetical proteinCG13531-PBFBgn0034786NONAnot annotatedNONANONA----------------ALHF_00756.g413876KA644750hypothetical proteininaF-D-PBFBgn0260812NONAnot annotatedNONANONA----------------GO:0005246GO:0016247ALHF_00757.g4141017KA644751Arginase familyarg-PAFBgn0023535MetabolismAmino acids m/tr52768Arginase/deacetylaseCL0302ArginasePF00491.16ArginaseArginase familyK01476E3.5.3.1, rocF, arg; arginase[EC:3.5.3.1]GO:0004053GO:0046872ALHF_00758.g415945KA644752GTP cyclohydrolase IPu-PCFBgn0003162MetabolismNucleotide m/tr55620Tetrahydrobiopterin biosynthesis enzymes-likeCL0334THBO-biosynPF01227.17GTP_cyclohydroIGTP cyclohydrolase IK01495E3.5.4.16, folE; GTP cyclohydrolase I[EC:3.5.4.16]GO:0003934GO:0060308ALHF_00760.g4161362KA644753HomeoboxCG11617-PBFBgn0031232RegulationDNA-binding46689Homeodomain-likeCL0123HTHPF05920.6Homeobox_KNHomeobox KN domain------GO:0003700GO:0043565ALHF_00761.g4171770KA644754Peptidase family M13CG9507-PAFBgn0031808Intra-cellular processesProteases55486Metalloproteases ("zincins"), catalytic domain\N\NPF05649.8Peptidase_M13_NPeptidase family M13------GO:0004222ALHF_00764.g4181536KA644755PresenilinPsn-PCFBgn0019947NONAnot annotatedNONANONACL0130Peptidase_ADPF01080.12PresenilinPresenilinK04505PSEN1, PS1; presenilin 1[EC:3.4.23.-]GO:0004190ALHF_00767.g4192601KA644756LIM domain proteinRassf-PAFBgn0039055RegulationDNA-binding57716Glucocorticoid receptor-like (DNA-binding domain)\N\NPF00412.17LIMLIM domain------GO:0005515GO:0008270ALHF_00768.g420783KA644757Proliferating cell nuclear antigenmus209-PAFBgn0005655InformationDNA replication/repair55979DNA clampCL0060DNA_clampPF02747.10PCNA_CProliferating cell nuclear antigen, C-terminal domainK04802PCNA; proliferating cell nuclear antigen--GO:0003677GO:0030337ALHF_00769.g4211086KA6447587 transmembrane receptor (Secretin family)mthl10-PEFBgn0035132RegulationSignal transduction63877Methuselah ectodomainCL0192GPCR_APF00002.197tm_27 transmembrane receptor (Secretin family)------GO:0004930ALHF_00771.g4221140KA644759CarboxylesteraseCG4757-PAFBgn0027584MetabolismOther enzymes53474alpha/beta-HydrolasesCL0028AB_hydrolasePF00135.23COesteraseCarboxylesterase family------GO:0004091ALHF_00776.g4241041KA644760Histone deacetylaseRpd3-PAFBgn0015805MetabolismAmino acids m/tr52768Arginase/deacetylaseCL0302ArginasePF00850.14Hist_deacetylHistone deacetylase domainK06067HDAC1_2; histone deacetylase 1/2[EC:3.5.1.98]GO:0003714GO:0004407GO:0005515ALHF_00778.g425993KA644761Eukaryotic and archaeal DNA primase small subunitDNApol-alpha50-PAFBgn0011762OtherUnknown function56747Prim-pol domainCL0243AEPPF01896.14DNA_primase_SEukaryotic and archaeal DNA primase small subunitK02684PRI1; DNA primase small subunit[EC:2.7.7.-]GO:0003887GO:0003896ALHF_00779.g4263903KA644762EF hand proteinDys-PCFBgn0260003GeneralGeneral47576Calponin-homology domain, CH-domainCL0220EF_handPF09068.6efhand_1EF hand------GO:0003779GO:0005198GO:0005200GO:0005509GO:0008092GO:0008270GO:0008307GO:0050699ALHF_00780.g4272172KA644763hypothetical proteinpen-PAFBgn0015527GeneralGeneral48371ARM repeat\N\NPF08144.6CPLCPL (NUC119) domainK14844PUF6; pumilio homology domain family member 6--GO:0003723ALHF_00781.g428594KA644764Immediate early response protein (IER)Chro-PAFBgn0044324InformationDNA replication/repair54160Chromo domain-like\N\NPF05760.7IERImmediate early response protein (IER)------ALHF_00783.g4292343KA644765Ligand-gated ion channelNmdar1-PAFBgn0010399RegulationDNA-binding53822Periplasmic binding protein-like ICL0030Ion_channelPF00060.21Lig_chanLigand-gated ion channelK05208GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1--GO:0004970GO:0004972GO:0005234ALHF_00784.g4301320KA649935EF hand proteinEps-15-PDFBgn0035060GeneralGeneral47473EF-handCL0220EF_handPF00036.27efhandEF hand------GO:0005509ALHF_00786.g431603KA644766tumor protein D52 familyCG5174-PAFBgn0034345NONAnot annotatedNONANONA\N\NPF04201.10TPD52Tumour protein D52 family------GO:0003824GO:0030170ALHF_00787.g432531KA644767hypothetical proteintay-PAFBgn0260938NONAnot annotatedNONANONA----------------ALHF_00788.g433615KA644768COP9 signalosome, subunit CSN8CG10306-PAFBgn0034654GeneralGeneral48371ARM repeatCL0123HTHPF10075.4PCI_Csn8COP9 signalosome, subunit CSN8K15028EIF3K; translation initiation factor 3 subunit K--GO:0003743GO:0043022ALHF_00793.g4352994KA644769Adaptinrb-PBFBgn0003210GeneralGeneral48371ARM repeatCL0020TPRPF01602.15Adaptin_NAdaptin N terminal regionK12397AP3B; AP-3 complex subunit beta--GO:0005488GO:0008565ALHF_00796.g4361341KA644770DNA polymerase phi----NONAnot annotatedNONANONA\N\NPF04931.8DNA_pol_phiDNA polymerase phiK02331POL5, MYBBP1A; DNA polymerase phi subunit[EC:2.7.7.7]ALHF_00799.g4372685KA644771Ankyrinwfs1-PCFBgn0039003NONAnot annotatedNONANONACL0465AnkPF12796.2Ank_2Ankyrin repeats (3 copies)K14020WFS1; wolfamin--GO:0004357GO:0005488ALHF_00801.g4381005KA644772RNA recognition proteinshep-PFFBgn0052423RegulationRNA binding, m/tr54928RNA-binding domain, RBDCL0221RRMPF00076.17RRM_1RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)------GO:0000166GO:0003723GO:0003729ALHF_00802.g4392164KA649936hypothetical proteinCG6498-PAFBgn0036511RegulationKinases/phosphatases56112Protein kinase-like (PK-like)\N\NPF08926.6DUF1908Domain of unknown function (DUF1908)K08789MAST; microtubule-associated serine/threonine kinase[EC:2.7.11.1]GO:0000287GO:0004674GO:0005524ALHF_00804.g4401128KA644773WD domain proteinwuho-PAFBgn0029857GeneralGeneral50978WD40 repeat-likeCL0186Beta_propellerPF00400.27WD40WD domain, G-beta repeatK15443TRM82, WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82--ALHF_00807.g4411500KA644774Putative transmembrane proteinCG2909-PAFBgn0030189NONAnot annotatedNONANONA\N\NPF10271.4Tmp39Putative transmembrane protein------ALHF_00808.g4421542KA644775BTB/POZ domain proteinTango10-PAFBgn0030330GeneralProtein interaction54695POZ domainCL0033POZPF00651.26BTBBTB/POZ domain------GO:0003674ALHF_00809.g4431362KA644776Syndecan domain proteinSdc-PCFBgn0010415NONAnot annotatedNONANONA\N\NPF01034.15SyndecanSyndecan domainK06257SDC; syndecan--GO:0004888GO:0008092ALHF_00813.g4441360KA649937Major Facilitator Superfamily proteinCG31106-PBFBgn0051106Intra-cellular processesIon m/tr103473MFS general substrate transporterCL0015MFSPF07690.11MFS_1Major Facilitator SuperfamilyK06258SV2; MFS transporter, VNT family, synaptic vesicle glycoprotein 2--ALHF_00814.g445982KA649938hypothetical proteinwah-PMFBgn0262527NONAnot annotatedNONANONA----------------ALHF_00815.g446711KA644777Chitin binding Peritrophin-Aobst-A-PBFBgn0031097MetabolismCarbohydrate m/tr57625Invertebrate chitin-binding proteinsCL0155CBM_14_19PF01607.19CBM_14Chitin binding Peritrophin-A domain------GO:0008061GO:0016490ALHF_00816.g447918KA644778HelicaseRm62-PHFBgn0003261GeneralSmall molecule binding52540P-loop containing nucleoside triphosphate hydrolasesCL0023P-loop_NTPasePF00271.26Helicase_CHelicase conserved C-terminal domainK12823DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2[EC:3.6.4.13]GO:0003676GO:0003729GO:0004004GO:0005515GO:0005524ALHF_00817.g448978KA6447792OG-Fe(2) oxygenase superfamily proteinPH4alphaNE1-PAFBgn0039780NONAnot annotatedNONANONACL0029CupinPF03171.152OG-FeII_Oxy2OG-Fe(II) oxygenase superfamilyK00472E1.14.11.2; prolyl 4-hydroxylase[EC:1.14.11.2]GO:0004656GO:0005506GO:0016702GO:0031418ALHF_00820.g449561KA644780DnaJjdp-PAFBgn0027654Intra-cellular processes