INTRODUCTION TO BIOCHEMISTRY

Rondang Soegianto

2009

Chemistry is the Study of Matter

and its Changes

- What is matter?

- What are the changes?

BIOCHEMISTRY = LIFE SCIENCE

Chemistry of living system related to

Functions and Needs of the system

Matter changes thru chemical reactions

Atoms interact to form a bond =

Chemical bonding

- Ionic bonds

- Covalent bonds

Ionic Bonds

Atoms that loses e- pos ion (cation)

Atom that acquires e- neg ion (anion)

Ex. Ca + 2 Cl CaCl2

Covalent Bond

Sharing of a pair of electrons between atoms

Ex. H2 , CH4

Functional Groups

1. Hydroxyl 6. Carbonyl 2. Aldehyde 7. Amine3. Carboxylic 8. Amide4. Ether 9. Thioester5. Ester 10. Phosphoester

Fat = Triacylglycerol

Ketoacids (α-Ketoglutaric acid)

Thioether -C-S-C- (Methionine