10 November 2008

• Finish Ch 12 Cardiovascular• Begin Ch 14 Respiratory Physiology• Lab this week: Frog heart physiology

– Review actions of ACh, Atropine, and EPI– Effects of temperature on HR– Producing heart blocks– Double-pithed

• Syllabus change: Digestion moved to end

RespiratoryPhysiologyThe physics of air flow1) Flow in tubes2) Ventilation

• Respiration is the overall movement of gases between the outside environment and the internal cells

O2

O2 CO2

CO2

But Carbon Dioxide reacts with water!

The major parts of the “airways,” along which air movements (ventilation) occur during breathing.

Upper

Respiratory

Tract

The Structure underlying the function:

Lower

Respiratory

Tract

BronchitisAsthma

Upper Tract Sleep Apnea & CPAP

Continuous Positive Airway Pressure

Larynx

The major parts of the “airways,” along which air movements (ventilation) occur during breathing.

Lower

Respiratory

Tract

Surgical resectionSurgical resection

Pulmonary arterial blood = low in O2Pulmonary arterial blood = low in O2

Figure 22.10

The relaxation/contractionof circular smooth musclelining these “airways’” determines how easily airflow can occur(bronchodilation vs.bronchoconstriction).

Most gas exchange occurs in the~8,000,000 alveolar sacs.

Figure 13-2

Anat

omic

alD

ead

Spac

e

• What does a river delta and your lungs have in common?

Figure 13-2

Anat

omic

al D

ead

Spac

e

Impaction

Sedimentation

Brownian Diffusion

Particle Filtration: deposition varies

DecreaseIn FlowRate

RespiratoryEpithelium

Mucus escalator

Figure 22.5

Smoker’s hackSmoker’s hack