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1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2. Vascular Hemodynamics Tufts OpenCourseWare © 2008 Tufts University Vascular Hemodynamics OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 1

1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

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Page 1: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

1. Basic Human Pathology Lecture #9 Vascular Hemodynamics

2. Vascular Hemodynamics

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 1

Page 2: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

3. Vascular Hemodynamics

4. Edema

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 2

Page 3: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

5. Edema

6. Edema

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 3

Page 4: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

7. Causes of Edema

8. Factors Affecting Fluid Transit Across Capillary Walls

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 4

Page 5: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

9. Causes of Edema

10. Edema

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 5

Page 6: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

11. Sequence of Events Leading to Systemic Edema

12. Vascular Hemodynamics: Slide 12

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 6

Page 7: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

13. Pulmonary Edema

14. Pitting Edema of the Subcutaneous Tissues

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 7

Page 8: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

15. Edema

16. Edema

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 8

Page 9: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

17. Ascites

18. Hyperemia

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 9

Page 10: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

19. Hyperemia

20. Chronic Passive Congestion – “Heart Failure Cell...

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 10

Page 11: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

21. Nutmeg Liver

22. Hemorrhage

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 11

Page 12: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

23. Hemorrhage

24. Hemorrhage

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 12

Page 13: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

25. Purpura = Petechiae and Ecchymoses

26. Petechial hemorrhages of the colonic mucosa / Fatal intracer...

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 13

Page 14: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

27. Vascular Hemodynamics: Slide 27

28. Vascular Hemodynamics: Slide 28

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 14

Page 15: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

29. Hemostasis

30. Normal Hemostatic Process Events

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 15

Page 16: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

31. Thrombosis

32. Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 16

Page 17: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

33. Thrombosis

34. Hemostasis / Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 17

Page 18: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

35. Hemostasis / Thrombosis

36. Hemostasis / Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

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Page 19: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

37. Vascular Hemodynamics: Slide 37

38. Hemostasis / Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 19

Page 20: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

39. Fibrinolytic System

40. Hemostasis / Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 20

Page 21: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

41. Vascular Hemodynamics: Slide 41

42. Vascular Hemodynamics: Slide 42

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 21

Page 22: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

43. Platelet Adhesion – Early / Fibrin Deposition - Late...

44. Vascular Hemodynamics: Slide 44

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 22

Page 23: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

45. Thrombosis

46. Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 23

Page 24: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

47. Thrombosis

48. Thrombosis

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 24

Page 25: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

49. Vascular Hemodynamics: Slide 49

50. Thrombosed (occlusive) Artery

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 25

Page 26: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

51. Heart Valve Vegetations (thrombi)

52. Mural Thrombi

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 26

Page 27: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

53. Thrombosis

54. Organization and Recanalization of Thrombus

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 27

Page 28: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

55. Organization and Recanalization of Thrombus

56. Embolism

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 28

Page 29: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

57. Embolism

58. Vascular Hemodynamics: Slide 58

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 29

Page 30: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

59. Large Pulmonary Artery Embolus

60. Embolism

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 30

Page 31: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

61. Embolism

62. Embolism

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 31

Page 32: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

63. Embolism

64. Embolism

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 32

Page 33: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

65. Embolism

66. Embolism

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 33

Page 34: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

67. Embolism

68. Embolism

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 34

Page 35: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

69. Infarction

70. Infarction

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 35

Page 36: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

71. White Infarcts / Red Infarcts

72. Infarction

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 36

Page 37: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

73. Infarction

74. Infarct Infarct – Red (lung) and Pale (spleen)

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Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 37

Page 38: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

75. Renal Infarcts

76. Infarction

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 38

Page 39: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

77. Venous Infarctions

78. Slow Occlusion of a Vessel

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 39

Page 40: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

79. Infarction

80. Vascular Hemodynamics

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 40

Page 41: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

81. Vascular Hemodynamics

82. Vascular Hemodynamics

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 41

Page 42: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

83. Vascular Hemodynamics

84. Vascular Hemodynamics

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 42

Page 43: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

85. Vascular Hemodynamics

86. Vascular Hemodynamics

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 43

Page 44: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

87. Vascular Hemodynamics

88. Clinical

Tufts OpenCourseWare © 2008 Tufts University

Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 44

Page 45: 1. Basic Human Pathology Lecture #9 Vascular Hemodynamics 2

89. Symptoms of Shock

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Vascular Hemodynamics

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 45