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Main components of female reproductive system A. Ovaries B. Uterine tubes C. Uterus D. Mammary gland Ovary:  Produces oocytes -oogenesis  Produces female sex hormones: o Oestrogens (theca interna cells) o Progesterone (CL) o Inhibin (granulosa cells) Uterine tubes:  Conducts ova towards uterus  Site of fertilisation Uterus:  Site of implantation Vagina:  Site of intoduction of spermatozoa  Birth canal Co-ordination of function due to  Hypothalamic-pituitary axis  Secretory status of tissues/organs The timing of secretion and the sites of action of hypothalamic, pituitary and ovarian hormones are essential to understanding the physiology of reproductive function. A: Ovary Three histological regions: 1. Cortex:  Cellular region: o Follicles = oocyte + follicular/granulosa cells stroma  Fibroblasts + collagen types I and III 2. Medulla: loose ct, bvs, nerves 3. Hilum: stalk-like region of entry/exit of bvs + nerves, ct Oocytes  Develop in the embryo ~6 weeks  Primordial germ cells from yolk sac colonise embryonic gonad.  Mitosis of primordial germ cells oogonia  several million  1 - 2 million at birth  ~400,000 at puberty  ~400 will ovulate, the rest become atretic (will degrade)

009 - Reproductive Histology

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