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Europcr2014 1.3
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EuroPCR25th annual meeting of the European Association of Percutaneous Cardiovascular Interventions (EAPCI)
Paris20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
Optimal duration of dual antiplatelet therapy
Commentary:
Dr Greg StarmerCairns Hospital
Date of preparation May 2014 │BRI001132
Disclaimer
• AstraZeneca abides by the Medicines Australia Code of Conduct (Edition 17) and AstraZeneca Global Policies, and as such will not engage in the promotion of unregistered products or unapproved indications.
• These highlights have been suggested by a group of cardiologists who attended EuroPCR 2014, compiled by an external medical writer and sponsored by AstraZeneca.
• AstraZeneca has obtained permission from EuroPCR, to utilise the selected content for educational purposes.
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EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
EuroPCR 2014Paris
20-23 May 2014
• Recommended durations of dual antiplatelet therapy, whether with clopidogrel, prasugrel or ticagrelor in addition to aspirin, are largely arbitrary. The optimal duration remains unknown.
• Current clinical trials, including the DAPT and ISAR-SAFE, will help to define the optimal duration of dual antiplatelet therapy.
• There is increased support for tailoring therapy to individual patients, for example 3-6 months for uncomplicated cases but >12 months in more complex cases (eg bifurcation stents, unprotected left main disease or long stents).
• With tailored therapy, it may be reasonable to briefly interrupt DAPT in ACS patients needing elective but semi-urgent surgery.
Commentary: Dr Greg Starmer
EuroPCR 2014Paris
20-23 May 2014
• More evidence is needed to guide the choice of antiplatelet therapy in patients also requiring anticoagulation, as triple therapy (DAPT + warfarin) carries a high bleeding risk and should generally be minimised.
• For the time being, novel oral anticoagulants are being regarded as equivalent to warfarin in this context, but more data are needed.
Commentary: Dr Greg Starmer
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