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DNA Replication
DNA Replication:
SEMICONSERVATIVE MODEL
FIG 16.10
This process is fueled by…nucleoside nucleoside triphosphatestriphosphates
Semi-conservative
DNA is made from DNA is made from 5’ to 3’5’ to 3’ and it is and it is read from 3’-5’.read from 3’-5’.
The 3’ end is the end which elongates (grows)
Leading & Lagging strands
•made 5’-3’
Okazaki fragments (are of the lagging strand)
ENZYMES:
•Helicase (not shown)
•DNA Polymerase
•ligase
Enzymes
•Helicase
•Single strand binding proteins
•Primase(RNA Primer)
•DNA Polymerase
•Ligase
•Nuclease and DNA Polymerase (both are repair enzymes)
Repairing mistakes
Telomeres
•Unfilled gap left at the ends of the DNA strands due to the use of RNA primers
•Eventual shortening of DNA over time
•Dolly, cancer, telomerase
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