Brainsgate Press Conf Dr Devlin

Where medical firsts happen FIRST

High Technology Stroke Update

Erlanger Southeast Regional Stroke CenterHigh Technology Stroke Update

• An Important Medical Research Milestone– Erlanger’s 15-year commitment to Stroke– TEAM APPROACH– International Partnerships

2006 American Heart Association Statistics• In US: 750 thousand strokes/year. # 3 Cause of Death, (#2 Worldwide,) # 1 Cause Adult Disability Occurs every 45 seconds & kills every 3 minutes. Society coast 2007 was $57.9 Billion.• In TN: Some Counties around Hamilton death rates from stroke

are 300% the national average.

Note: Data for the years 2000 to 2050 are middle-series projections of the population.Reference population: These data refer to the resident population.Source: US Census Bureau, Decennial Census Data and Population Projections.

Total Number of Persons Age 65 or Older, by Age Group, 1900 to 2050

Millions80

60

40

20

01900 1950 2000 2050

65 or older

85 or older

Projected

Pleiades Foundation (Non-profit)

National Stroke Intervention Training Center

Pleiades+Erlanger+UTCOMC

“Time is Brain”

Current Stroke Treatment Options

The BrainsGate ISS Device

BrainsGate: The ISS Implant

Initial Results with the Brainsgate Device

• 99 Patients• 11 Sites in Germany, Hungary, India and Israel

Exact Placement Required

Dr Peter Hunt’s Surgical Team at Erlanger

March 6, 2009 – 1st US patient implanted.

March 16, 2010 – 1st US patient implanted using the new GuideView System.

Brainsgate

Brainsgate Animation

March 16, 2010First GuideView Patient in the US

• 73 yo female.• HX: Hypertension and Hx of breast cancer and

Adriamycin cardiomyopathy.• Works full time in a yarn factory • Stroke witnessed at 9:30AM. • 911 -> Hamilton Med Center -> Erlanger Med Center. • Unable to speak, blind on right, weak on the right.• NIHSS = 15 initially.•Not candidate for t-PA or MERCI/Penumbra Rx.

Implantation videos

In Summary

•Unique Research Device that Extends Window to 24 hours. •Represents the Best High Tech Solutions from the International Research Community.•Analogous to other Chattanooga Programs – •It is not an accident that these and other Firsts occur at Erlanger.

Erlanger Southeast Regional Stroke CenterHigh Technology Stroke Update

Questions

March 6, 2009First Brainsgate Patient in the US

• 56 yo female. Unremarkable PMH.

• Went to bed at 8PM.

• Found by her husband 6:30AM

•In ER: Confused, Blind on the left, paralyzed on the left. NIHSS = 11.

•Out of the Window for t-PA, MERCI, etc.

•Etiology of stroke: Hypercoaguable state