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Volume 8, Number 1, January 2021Neurology.org/NN
A peer-reviewed clinical and translational neurology open access journal
ARTICLE
Seizure-related 6 Homolog Like 2 Autoimmunity e916
ARTICLE
Overlapping Central and Peripheral Nervous System Syndromes in MOG Antibody–associated Disorders e924
VIEWS & REVIEWS
Chitinases and Chitinase-like Proteins as Biomarkers in Neurologic Disorders e921
ARTICLE
Overweight/Obesity in Young Adulthood Interacts With Aspects of EBV Infection in MS Etiology e912
Academy OfficersJames C. Stevens, MD, FAAN, PresidentOrly Avitzur, MD, MBA, FAAN, President ElectAnn H. Tilton, MD, FAAN, Vice PresidentCarlayne E. Jackson, MD, FAAN, SecretaryJanis M. Miyasaki, MD, MEd, FRCPC, FAAN, TreasurerRalph L. Sacco, MD, MS, FAAN, Past President
CEO, American Academy of NeurologyMary E. Post, MBA, CAEChief Executive Officer201 Chicago AveMinneapolis, MN 55415Tel: 612-928-6100
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Morgan S. Sorenson, Managing EditorNeurology® Neuroimmunology & NeuroinflammationNeurology® Genetics
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A peer-reviewed clinical and translational neurology open access journal Neurology.org/NN
Neurology® Neuroimmunology & Neuroinflammation
EditorJosep O. Dalmau, MD, PhD
Deputy EditorScott S. Zamvil, MD, PhD, FAAN
Associate EditorsMarinos Dalakas, MD, FAANMichael Heneka, MDDennis Kolson, MD, PhDFriedmann Paul, MD
Editorial BoardSergio E. Baranzini, PhDSusanne Benseler, MDJeffrey L. Bennett, MD, PhD, FAANSeverine Boillee, PhDRiley M. Bove, MD, MMSCChiara Briani, MDFabienne Brilot, PhDMatthijs C. Brouwer, MD, PhDWolfgang Bruck, MDDavid B. Clifford, MD, FAANAnne Haney Cross, MDRussell C. Dale, MBChB, MRCP, PhDThomas G. Forsthuber, MDKazuo Fujihara, MDChristian Geis, MDJeffrey M. Gelfand, MD, MAS, FAANFrancesc Graus, MD, PhDKerstin Hellwig, MDMatilde Inglese, MD, PhDTakahiro Iizuka, MDLuisa Klotz, MD
Kristen M. Krysko, MD, MASAnnette Langer-Gould, MD, PhDFrank Leypoldt, MDErin Longbrake, MD, PhDAndrew McKeon, MDAnne Louise Oaklander, MD PhD,
FAAN, FANAAnne-Katrin Probstel, MDRichard M. Ransohoff, MDAlbert Saiz, MD, PhDJens Schmidt, MD, FEAN, FAANChristine Stadelmann, MDIsrael Steiner, MDLawrence Steinman, MDSilvia N. Tenembaum, MDCharlotte E. Teunissen, PhDMaarten J. Titulaer, MD, PhDAri Waisman, PhDGregory F. Wu, MD, PhD
Neurology® Journals
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Section Editors
BiostatisticsRichard J. Kryscio, PhDSue Leurgans, PhDV. Shane Pankratz, PhD
Classification of Evidence EvaluationsGary S. Gronseth, MD, FAAN
Equity, Diversity, & InclusionRoy H. Hamilton, MD, MS, FAANHolly E. Hinson, MD, MCR, FAAN
PodcastsStacey L. Clardy, MD, PhD, FAANJeffrey B. Ratliff, MD, Deputy Podcast Editor
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Scientific Integrity AdvisorDavid S. Knopman, MD, FAAN
Classification of Evidence Review TeamMelissa J. Armstrong, MDRichard L. Barbano, MD, PhD, FAANRichard M. Dubinsky, MD, MPH, FAANJeffrey J. Fletcher, MD, MScGary M. Franklin, MD, MPH, FAANDavid S. Gloss II, MD, MPH&TMJohn J. Halperin, MD, FAANJason Lazarou, MSc, MDSteven R. Messe, MD, FAANPushpa Narayanaswami, MBBS, DM, FAANAlex Rae-Grant, MD
Vision Neurology® Neuroimmunology &Neuroinflammation will be the premierpeer-reviewed journal in the fields ofneuroimmunology and neuroinflammation.
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TABLE OF CONTENTS Volume 8, Number 1, January 2021 Neurology.org/NN
Editor’s Corner
e925 N2 Year in ReviewJ. Dalmau, M.C. Dalakas, D.L. Kolson, F. Paul, and S.S. Zamvil
Open Access
Editorial
e932 Obesity’s Role in MS: An Intervention Target WithPossible InteractionsK. C. Fitzgerald, and E. M. Mowry
Open Access
Articles
e906 Chitinase 3–Like 1 and Neurofilament Light Chain inCSF and CNS Atrophy in MSR. Schneider, B. Bellenberg, B. Gisevius, S. Hirschberg,R. Sankowski, M. Prinz, R. Gold, C. Lukas, and A. Haghikia
Open Access Class of Evidence
e904 Mild Progressive Multifocal LeukoencephalopathyAfter Switching FromNatalizumab to OcrelizumabA.A. Toorop, Z.Y.G. van Lierop, E.E.M. Strijbis, C.E. Teunissen,A. Petzold, M.P. Wattjes, F. Barkhof, B.A. de Jong,Z.L.E. van Kempen, and J. Killestein
Open Access
e907 Clostridium Bolteae Is Elevated in NeuromyelitisOptica Spectrum Disorder in India and SharesSequence Similarity With AQP4L. Pandit, L.M. Cox, C. Malli, A. D’Cunha, T. Rooney, H. Lokhande,V. Willocq, S. Saxena, and T. Chitnis
Open Access
e908 Laquinimod Dampens IL-1β Signaling andTh17-Polarizing Capacity ofMonocytes in PatientsWith MSS. Engel, V. Jolivel, S.H.-P. Kraus,M. Zayoud, K. Rosenfeld, H. Tumani,R. Furlan, F.C. Kurschus, A. Waisman, and F. Luessi
Open Access
e913 Anti-CD20 Therapies and Pregnancy inNeuroimmunologic DisordersT. Kumpfel, S. Thiel, I. Meinl, A.I. Ciplea, A. Bayas, F. Hoffmann,U. Hofstadt-van Oy, M. Hoshi, J. Kluge, M. Ringelstein, O. Aktas,M. Stoppe, A. Walter, M.S. Weber, I. Ayzenberg, and K. Hellwig
Open Access
e915 Placental Transfer of NMDAR Antibodies CausesReversible Alterations in MiceA. Garcıa-Serra, M. Radosevic, A. Pupak, V. Brito, J. Rıos, E. Aguilar,E. Maudes, H. Ariño,M. Spatola, F. Mannara,M. Pedreño, B. Joubert,S. Gines, J. Planaguma, and J. Dalmau
Open Access
e916 Seizure-related 6 Homolog Like 2 Autoimmunity:Neurologic Syndrome and Antibody EffectsJ. Landa, M. Guasp, M. Petit-Pedrol, E. Martınez-Hernandez,J. Planaguma, A. Saiz, R. Ruiz-Garcıa, L. Garcıa-Fernandez,J. Verschuuren, R. Saunders-Pullman, L. Ramirez-Gomez,M.D. Geschwind, J. Dalmau, L. Sabater, and F. Graus
Open Access
e917 Eastern Equine Encephalitis and Use of IVImmunoglobulin Therapy and High-DoseSteroidsD.R. Wilcox, S.I. Collens, I.H. Solomon, F.J. Mateen, and S.S. Mukerji
Open Access
e911 Time Course of Dementia Following Sepsis inGerman Health Claims DataT. Fritze, G. Doblhammer, C.N. Widmann, andM.T. Heneka
Open Access
e920 Mendelian Randomization Study Shows No CausalEffects of Serum Urate Levels on the Risk of MSA. Harroud, J.B. Richards, and S.E. Baranzini
Open Access
e924 Overlapping Central and Peripheral NervousSystem Syndromes in MOG Antibody–associatedDisordersS. Rinaldi, A. Davies, J. Fehmi, H.N. Beadnall, J. Wang, T.A. Hardy,M.H. Barnett, S.A. Broadley, P. Waters, S.W. Reddel, S.R. Irani,F. Brilot, R.C. Dale, and S. Ramanathan,the Australian and New Zealand MOG Study Group
Open Access
Cover ImageIntrauterine exposure to patients’ IgG causes a transient increase ofdendritic complexity and decrease of spine density. Representativeimages by confocal microscopy of a DiI-stained CA1 hippocampalpyramidal neuron, and a secondary apical dendrite, with morphologicallyclassified dendritic spines. Stylized by Madeleine Sendek, MPH, DigitalMarketing Communications Coordinator.See page e915
Continued
e926 High Serum Neurofilament Associates With DiffuseWhite Matter Damage in MSM. Saraste, S. Bezukladova, M. Matilainen, J. Tuisku, E. Rissanen,M. Sucksdorff, S. Laaksonen, A. Vuorimaa, J. Kuhle, D. Leppert, andL. Airas
Open Access
e928 Mesenchymal Stem Cell-Derived Neural ProgenitorsinProgressiveMS:Two-YearFollow-UpofaPhaseIStudyV.K. Harris, J.W. Stark, S. Yang, S. Zanker, J. Tuddenham, andS.A. Sadiq
Open Access
e931 Interleukin-15 Enhances Proinflammatory T-CellResponses in Patients With MS and EAEC. Laurent, G. Deblois, M.-L. Cleenet, A. C. Moratalla, N. Farzam-kia,M. Girard, P. Duquette, A. Prat, C. Larochelle, and N. Arbour
Open Access
e912 Overweight/Obesity in Young Adulthood InteractsWith Aspects of EBV Infection in MS EtiologyA. Karin Hedstrom, N. Brenner, J. Butt, J. Hillert, T. Waterboer,T. Olsson, and L. Alfredsson
Open Access Editorial, p. e932
Clinical/Scientific Notes
e905 LGI1 Encephalitis With Squamous Lung-CellCarcinoma: Resolution After Tumor ResectionA. Virupakshaiah, M.C. Dalakas, N. Desai, S. Mintzer, and J. Ratliff
Open Access
e910 A Case of Neonatal Onset Multisystem InflammatoryDisease Supporting a Role of Interleukin-1β inMoyamoya SyndromeF. Wohlrab, C. Bauknecht, C. Meisel, and J.P. Dreier
Open Access
e922 Tumefactive Inflammatory Lesions in JuvenileMetachromatic LeukodystrophyK. Meier, J. Gartner, and P. Huppke
Open Access
e927 Combination of Teriflunomide and Interferon asFollow-UpTherapyAfter Fingolimod-Associated PMLB. Fischer-Barnicol, J. Oechtering, J. Kuhle, J. Lorscheider,L. Kappos, and T. Derfuss
Open Access
Views & Reviews
e909 Intermediate Uveitis Associated With MS: Diagnosis,Clinical Features, Pathogenic Mechanisms, andRecommendations for ManagementA. Abraham, L. Nicholson, A. Dick, C. Rice, and D. Atan
Open Access
e914 IsMSAffecting theCNSOnly? Lessons FromClinic toMyelin PathophysiologyE. Oudejans, A. Luchicchi, E.M.M. Strijbis, J.J.G. Geurts, andA.-M. van Dam
Open Access
e918 Targeting B Cells to Modify MS, NMOSD, andMOGAD: Part 1J. Graf, J. Mares, M. Barnett, O. Aktas, P. Albrecht, S.S. Zamvil, andH.-P. Hartung
Open Access
e919 Targeting B cells to Modify MS, NMOSD, andMOGAD: Part 2J. Graf, J. Mares, M. Barnett, O. Aktas, P. Albrecht, S.S. Zamvil, andH.-P. Hartung
Open Access
e921 Chitinases and Chitinase-Like Proteins as Biomarkersin Neurologic DisordersR. Pinteac, X. Montalban, and M. Comabella
Open Access
e923 Presentations and Mechanisms of CNS DisordersRelated to COVID-19M. Bodro, Y. Compta, and R. Sanchez-Valle
Open Access
Diagnostic and Treatment Challenges
e929 Treating MS After Surviving PML: DiscreteStrategies For Rescue, Remission, andRecovery Patient 1: From the NationalMultiple Sclerosis Society Case ConferenceProceedingsN. Anadani, M. Hyland, R. Alejandro Cruz, R. Lisak, K. Costello,E.O. Major, Y. Jassam, E. Meltzer, T.C. Varkey, M.S. Parsons,A.D. Goodman, J.S. Graves, S. Newsome, S.S. Zamvil, E.M. Frohman,and T.C. Frohman
Open Access
e930 Treating MS After Surviving PML: DiscreteStrategies for Rescue, Remission, andRecovery Patient 2: From the NationalMultiple Sclerosis Society Case ConferenceProceedingsR. Alejandro Cruz, N. Hogan, J. Sconzert, M. Sconzert, E.O. Major,R.P. Lisak, E. Melamed, T.C. Varkey, E. Meltzer, A. Goodman,O. Komogortsev, M.S. Parsons, K. Costello, J.S. Graves, S. Newsome,S.S. Zamvil, E.M. Frohman, and T.C. Frohman
Open Access
Correction
e934 Monitoring of Radiologic Disease Activity by SerumNeurofilaments in MS
Open Access
e938 Identification of Circulating MOG-Specific B Cells inPatients With MOG Antibodies
Open Access
e949 Acute Disseminated Encephalomyelitis AfterSARS-CoV-2 Infection
Open Access
TABLE OF CONTENTS Volume 8, Number 1, January 2021 Neurology.org/NN
2021;8; Neurol Neuroimmunol Neuroinflamm 8 (1)
This information is current as of January 1, 2021
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