SFC Brain Imaging Research Centre TREVOR CARPENTER trevor.carpenter@ed.ac.uk Data Management in...

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SFC Brain Imaging Research Centre

TREVOR CARPENTERtrevor.carpenter@ed.ac.uk

Data Management in

Brain Imaging

Overview

SBIRC + SINAPSE

Regulatory Framework

Project Data

Current Practice

Current Developments

SBIRC

SFC Brain Imaging Research Centre• Situated at WGH• ~12,000 subjects studied in 11 yrs• Provides Imaging and technical support for

studies in:• Psychiatry• Psychology• Stroke• Oncology

WE ALSO DO OUR OWN RESEARCH!

SINAPSE

SINAPSE

• Consortium of six Scottish universities

• Collaborative research in Brain Imaging

• Support and connections to CRNs

• Data distribution, storage and cataloguing• Second phase to provide processing and

applications

SBIRC + SINAPSE

Who do we acquire imaging from:

NHS Patients

– Service provision to NHS

NHS Patients in Research studies

Volunteers

Regulatory Framework

Data Protection Act:Personal data should not be held longer than necessaryCannot be reused

R&D Ethics Committee:Time frame should be placed upon retention periodCannot be reused

MRHA:Data should be retained

Project Data

ACTIVITY!

BOP

Ethics, R&D

Insurance

Internal Forms

Raw Data

‘Image Data’

Subject Data

Paradigm

Proc’ Data

‘Image Data’

Study Results

Data Bases

Publications

Reports

Journal Papers

Applications

Source Code

Processing scripts

ARCHIVECOMMUNITY

RESOURCE

ACTIVITY

Project Data

Raw Data:

Usually in standard format (DICOM, e-Prime)

Processed Data:

Various formats (often excel, word)

Varies from project to project

Software:

Often closed source

No version control

Current Practice

Raw Data:

Archived on CD / Tape - NAS

Processed Data:

Responsibility of PI

Software:

Version control available

poor uptake

Not centrally available

Not open source

Future Developments

SOPs to cover archiving of project data –

Including:

Creation of data dictionaries

Documenting analysis procedures

Specifying preferred data formats

BUT….

not popular – does not publish papers (RAE)!

HOWEVER….

Some data is very valuable and should be captured

(LBC 1936, 1921 Cohort)