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Presentation of the Presentation of the ClearPEM-Sonic ClearPEM-Sonic mammography mammography scannerscanner
ClearPEM-SonicClearPEM-Sonic
2
Breast cancer:Breast cancer:
The most frequent cancer in women
One in nine women has breast cancer in her life
X-ray mammographyX-ray mammography
Standard in breast cancer diagnosis
Based in structural tissue changesBased in structural tissue changes
High rate of false-positiveHigh rate of false-positive
Less reliable in dense breasts Less reliable in dense breasts false negatives
Breast cancerBreast cancer
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PET mammography
X-ray mammography
PET mammographyPET mammography
PET and breast cancerPET and breast cancer•PET/FDG has good sensitivity in
breast cancer diagnosis
Radioactive tracerRadioactive tracer•FDG : glucose associated to
positron emitter F-18•Glucose has strong affinity to
cancer cells
PEM ScannerPEM Scanner•Positron Emission MammographyPositron Emission Mammography•PET equipment dedicated to breast PET equipment dedicated to breast
and axila examsand axila exams•Good spatial resolution ( ~ mm)Good spatial resolution ( ~ mm)•Good sensitivityGood sensitivity
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New technology based in fast crystals (LSO) and avalanche photodiodes (APD) associated to low-noise integrated electronics
The new electronics has the highest integration density available worldwide: compact detectors with DoI capability
Scanner with excellent spatial resolution (1.3 mm)
Integration with ultra-sound probe with elastography from company Supersonic Imagine.
ClearPEM-Sonic technologyClearPEM-Sonic technology
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Detector and Front End ElectronicsDetector and Front End Electronics
LYSO:Ce 2x2x20 mm3
4x8 matrix (BaSO4 walls)S8550
16 Supermodules
32 Frond End Electronic Boards
Hamamatsu
Supermodules Integration Detector modules
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1. Water Cooling Plates 4. On-Detector Cabling
2. Supermodules 5. Service Board (LV distribution; HV regulation; Control & Monitoring)
3. Patch Panel 6. HV Matrix (HV distribution)
1
45
6
12
3
4
Detector Heads IntegrationDetector Heads Integration
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Service Rack
Workstation
DSS – Detector Safety System
DAE – Data Acquisition Electronics
HV Power Supply (500V)
LV Power Supply (3V2, 5V)
Service Manager
Acquisition Manager / Data Storage
Transformer
Data Acquisition and ServicesData Acquisition and Services
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Spatial resolutionSpatial resolution
Resolution transaxial: 1.3 mm
DoI capability allows sharp imaging
With DoI
5 mm
1 mm
Without DoI
3.0 mm
2.5 mm2.0 mm
1.5 mm
1.2 mm
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Animal imagingAnimal imaging
tumorbladder
3D OSEM6 it. – 4 sub.
2D OSEM3 it. – 4 sub.
FDG scanF-18 scan
After injection
1h after
Bone scan
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