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Learning. Quantifying Learning Beyond Exams…. Principles of Neural Science ( Kandel ): Chapter 63. Terms used to quantify learning in animal models:. Habituation - animal is less reactive to an external stimulus Sensitization - animal is more reactive to an external stimulus - PowerPoint PPT Presentation

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Learning

Quantifying Learning Beyond Exams…..

Principles of Neural Science (Kandel): Chapter 63

Terms used to quantify learning in animal models:

• Habituation- animal is less reactive to an external stimulus

• Sensitization- animal is more reactive to an external stimulus

• Conditioning (albeit it classical or operant)- behavioral or physiological events are reinforced by pairing two external stimuli that are inherently mutually exclusive (bell and food)

Neuronal Identification of Habituation vs Sensitization

Neuronal Identifications of Habituation

Neuronal Identifications of Habituation

Neuronal Identifications of Sensitization

Neuronal Identifications of Sensitization (Short-Term, Cytoplasmic)

Neuronal Identifications of Sensitization (Long-Term, Nuclear)

LTP vs LTD in the hippocampus

LTP: long-term potentiationLTD: long-term depression

LTP vs. LTD is dependent on the number of connections and successful transmissions

This results in a change in the intensity of neuronal firing, pre-synaptically

And in a change in receptor expression, post-synpatically

The fruit fly as a powerful tool to manipulate learning

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