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Is there any evidence support effectiveness of coffee enema?. Truth and Myth Pisaln Mairiang MD. Searching strategy. Pubmed (no limit) Keywords: Coffee enema, Colonic hydrotherapy Colonic irrigation. Searching: coffee enema. - PowerPoint PPT Presentation
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Is there any evidence Is there any evidence support effectiveness of support effectiveness of
coffee enema?coffee enema?Truth and MythTruth and Myth
Pisaln Mairiang MD.Pisaln Mairiang MD.
Searching strategy
• Pubmed (no limit)
Keywords: Coffee enema,
Colonic hydrotherapy
Colonic irrigation
Searching: coffee enema
Historical aspects of enema therapyHistorical aspects of enema therapy
• An ancient theory of autointoxication by intestinal waste products.
• Had been practicing among ancient Chinese, Hindu, Egyptian medicine
NJ Taffinder et al Colorectal disease 2004;6:258-60
IndicationsIndications
asthma,allergies, arthritis, back pain, headache, insomnia, hyperlipidemia, bad breath, hypertension, mental disorders, alcoholism, ulcerative colitis, cancers and liver insufficiency.
Gerson’s hypothesis
Bacterial and food waste product
Bile flow
Alteration of Immune system
asthmaallergies arthritis
intoxication
headache, insomnia,
bad breath, mental disorders,
cancers and liver insufficiency.
Bile salt enterohepatic recirculationBile salt enterohepatic recirculation
Gerson’s hypothesis
Bacterial and food waste product
Bile flow
Repair of Immune system
asthmaallergies arthritis
detoxication
headache, insomnia,
bad breath, mental disorders,
cancers and liver insufficiency.
Scientific background of coffee enema
• Anaerobic decreased energy production and promote
cancer
• Coffee stimulate bile formation and flow
• Colestol compounds present in coffee act as
detoxicants by stimulate liver GST
• Cancer cells can be killed by inflammatory
reaction
NO
NO
NO
Yes/No
Coffee enema and cancerCoffee enema and cancer
tumor No. response Clinical course
melanoma 9 n/a Within natural history
Prostatemetastasis
21
n/acr
Within natural historyElevation of AP return to normal
Breast 2 n/a Residue mass post biopsy
Low gradelymphoma
3 1cr2n/a
2 with convention treatment1 regressed
endometrium 3 1cr1n/a1pd
1 ca in situ1 hysterectomy
Ca cervix 1 n/a 1a with conization
astrocytoma 1 pd Slow progresive disease
gastrinoma 1 pd Liver met and slow progressive
pancreas 2 2n/a No tissue prove
Hard palate 1 sd Positive biopsy
bladder 1 1cr Excision chemo and cystectomy
Leed A, et al. Lancet 1990;15:677-2
Safety and Safety and complicationscomplications
Complications of coffee enemaComplications of coffee enema
• Sporadic cases of deaths related to coffee enemas :• Pulmonary enema and septicemia in 46-year-old woman diagnosed as
colitis • 37-year-old woman with carcinoma of the breast developed
hyponathemia, hyperkalemia and abdominal pain with dyspnea
John W. Eisele, Donald T. Reay. JAMA 1980;244(14):1608-9.
• Perineal gangrene and rectal perforation Tan MP et al Ann Acad Singapore 1999;28:583-5
• Potassium depletion by enemas Dumning MF, Plum F. Am J Med 1956;789-92.
• Water intoxication Ziskind A, Gelis SS. J Dis Child 1958;699-04.
• Polymicrobial enteric septicemia from coffee enemasMargolin KA, Green MR. West J Med 1984;140(3):460
• Report cases of colonic injury (Burn) from Thai endoscopists
Summary on colonic hydrotherapySummary on colonic hydrotherapy
• Colonic hydrotherapy is effective in treatment constipation and hepatic encephalopathy
• There is no scientific evidence of its effectiveness
• To answer for effectiveness of coffee enema need controlled trail study. possible or impossible
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