Disease Progression in Multiple Sclerosis: Predicting Outcomes

Disease Progression in Multiple Sclerosis: Predicting Outcomes

Learning Objective

Disease Progression vs Suboptimal Treatment

Response

How Do We Assess Disease Activity?

Patient Presentation

Patient Presentation (cont)

Debra’s 2009 Brain MRI (FLAIR)

Debra’s 2009 Cervical Spine MRI

Patient Presentation (cont)

Risk Factors for Progression

Debra’s Risk Factors

How Do We Measure Disease Progression?

Clinical Disease: Relapses

Clinical Disease: Disability

In Your Opinion, What Is The Best Way to Assess Disease Activity In

Patients With MS?

Long-term Outcomes: CIS and MRI

Long-term Outcomes: Risk Factors

Long-term Outcomes: Disability

Debra’s 2009 FLAIR MRI

Debra’s 2010 FLAIR MRI (Postpartum)

MRI Assessment

Suboptimal Response Despite DMT

At What Disease Activity Threshold Do You Change a DMT?

Challenge of Switching Medications

Abbreviations

References

References (cont)