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Digital Health: Connecting Your Medicines to the Internet Means Better Care at Lower Cost
George M. Savage, MDCofounder & Chief Medical Officer
May 2, 2013
3©2013 Proteus Confidential
PersonalMedicalRecords
Percent of People with Type 2 Diabetes
<4%
4%
5%
7%
9%
>12%
Chronic Illness is an Enormous 21st Century Medical Challenge
4©2013 Proteus Confidential
Over 50 Percent of Prescription Medicines are Not Taken Correctly
WHO 20033
•Poor adherence to treatment of chronic diseases is a worldwide problem of striking magnitude
• Adherence to long-term therapy for chronic illnesses in developed countries averages 50%.
•The impact of poor adherence grows as the burden of chronic disease grows worldwide
•The consequences of poor adherence to long-term therapies are poor health outcomes and increased health care costs
•Improving adherence also enhances patients’ safety
•Adherence is an important modifier of health system effectiveness”
Medication adherence in heart failure1
Sources: (1) Hauptman J, Heart Fail rev 2008;13:99(2) Wong J, Can J Neurol Sci 2011; 38: 429(3) Sabate E, WHO 2003, pp xiii-xiv.
Medication adherence in multiple sclerosis2
8©2013 Proteus Confidential
Digital Medicines Deliver a Continuous, Unified Picture of Life
TherapeuticInformation
• Medication• Dose• Timing• Adherence• Supply Chain
PhysiologicInformation
• Heart Rate• Respiration• Activity• Posture• Gait• Sleep• Stress• Temperature
Mobile Information
• Sociability• Engagement• Cognitive Assessment• Environment• Location• Context
Subjective Information
• Side Effects• Symptoms• QOL• Mood• Emotion
9©2013 Proteus Confidential
Patient Engagement is the New Blockbuster “Drug”
Believe
Frame
KnowPrompt
Act
Reinforce
10©2013 Proteus Confidential
As With Phones, Complexity Invisible to User and Privacy Assured
Web/Mobile Applications
Patient/Caregiver Networks
Clinician and Clinical trial tools
Analytics
Patch attached to user and Paired to Phone, data upload periodic and
automatic, always on
Phone receives data from Patch, forwards to cloud. Analytics returned from
cloud
Ingestible sensor
activated upon fluid contact
11©2013 Proteus Confidential
$32B HF cost forecast to grow to $70B by 2030 (source: AHA)
25% of 1M discharged HF patients readmitted within 30 days
Overwhelming majority of readmissions are preventable
Solution: Digital health system to monitor medication taking and patient response
Opportunities from Heart Failure to Tuberculosis to HIV and More
12©2013 Proteus Confidential
• How best to regulate and reimburse cross-disciplinary digital health platform?
• How to allow business model innovation yielding improved patient care and productivity gains that lower cost?
• How to allow public and private sector payers to experiment with new, possibly transformative digital health technologies?
• How to keep platform implementation patient-centric, allowing the individual to control privacy, particularly the flow of personally-generated data?
• Blue ribbon panel• Innovators and policymakers tasked with exploring what steps are needed to
get digital health to patients
• White paper/report to Congress• Scientific innovations associated with digital health platform technologies,
challenges from regulatory and reimbursement perspectives, and potential policy solutions
Policy Considerations and Next Steps
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