Cajal and his studies on retina -...

Cajal and his studies on retina

Luis AlfaroFisabio Medical Ophthalmology

Hospital 9 de Octubre

Valencia. Spain

31st European Congress of Pathology

Nice, 7-11 September 2019

Enterprise | Interest

...

I hereby declare that I haven't had any business or personal interest

in any industrial enterprises

Santiago Ramón y Cajal(1952-1934)

14:26 3

1876

Zaragoza

1884

Valenciaca 1890

Barcelona

1905

Madrid

14:26 5

14:26 6

His parents:

Justo Ramón and Antonia Cajal

14:26 7

Cajal with his brother Pedro, sisters Pabla and

Jorja and mother Antonia

Cajal’s family in 1895:Silveria, Santiago, Fe, Cajal, Paula, Jorge and Pilar

Cajal family in 1905Fe, Paula, Pilar, Santiago and Luis

Cajal and Federico Olóriz

playing chess, 1898

Cajal mentors

14:26 11

Aureliano Maestre de San

Juan 1828-1890

Spanish Society of

Histology 1874

Luis Simarro

1851-1920

14:26 12

Enriqueta Lewy

Rodríguez

Cajal’s secretary

Board for Extension of Studies and Scientific Research Junta de Ampliación de Estudios (JAE)

Santiago Ramón y Cajal Marcelino Menéndez Pelayo

José Castillejo Duarte

1514:26

14:26 16

Hospital San Carlos. Madrid ca 1930

14:26 17

Lafora, Domingo Sánchez, José Miguel Sacristán, Miguel Gayarre, Nicolás Achúcarro

Cajal, Luis Rodríguez Illera, Juan de Dios Sacristán, Tomás García de la Torre

(janitor), Jerónimo (autopsy assistant)

. Rodríguez Díaz, Sapena, Sáinz de Aja, Ramón y Cajal, Tello and Bengoa;

Standing: Torres Alonso, Castillo Y Achúcarro, 1915

14:26 23

Ophthalmologist disciples

Galo Leoz1879 -1990

Letter toLorente de NoOctober fifth, 1934

14:26 25

14:26 26

Cerebral cortex. Golgi staining

14:26 27

Pyramidal cellsGolgi staining (Cajal, 1890). Confocal microscopy

14:26 28Cajal y sus dibujos: ciencia y arte

JAVIER DE FELIPE (Instituto Cajal, CSIC, 28002-Madrid)

14:26 29

To my dear friend Dr. Juan Bartual. In proof of

affection and consideration. The author

Cajal and Juan Bartual,

Valencia,ca. 1897

Structure of the Mammalian Retina

La retine des vertebresLa cellule vol. IX fasc. 1. 1892

14:26 33

14:26 34

Dawn Hunterhttp://dawnhunterart.blogspot.com/2016/02/drawing-santiago-ramon-y-cajals.html

14:26 35

Carmine of Grenacher staininga: rod and cones; b nuclei of rods and cones; c: displaced bipolar

cells; d: enlaged basal cones; e: brush horizontal cell; f: giant amacrine cell; s, t: displaced granular layer cells

14:26 36

14:26 37

14:26 38

14:26 39

The frog hunter:Federico Arias

14:26 40

Dog and ox retinaamacrine and ganglion cellsdouble impregnation of silver chromate

14:26 41

Horizontal cells of the adult dog's retina

14:26 42

Outer horizontal cells of the ox retinaPerpendicular section of the ox retina:

c, d: amacrine cells: e: small ganglionar cell, g, h, I j: neuroglia cells

14:26 43

Ox retinaExternal horizontal cells

External horizontal cell in sideway cut section with axon (axle cylinder)Retinal nerve elements stained with methylene blue (Erhlich-Dogiel method)

14:26 44

Hen retina

14:26 45

a,b,c: ganglionar cells

d,e: horizontal plexus

cells: f: cells generating

double plexiform layer

Colorful frog a: internal part of rod, b: outer part with clear bands, c: cone d: filiform rod, e: conical rod i:

cone body

14:26 46

Thank you

14:26 47

Cajal, portrait by Joaquin SorollaZaragoza Museum