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Normal Anion Gap Hyperchloremic acidosis GI or renal Loss of bicarbonate Impaired renal acid secretion Reabsorption of Chloride Examples: Diarrhea Renal Tubular Acidosis Carbonic Anhydrase Inhibition. High Anion Gap Acid retention Examples: Lactic Acidosis: most common - PowerPoint PPT Presentation
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Anion GapSodium - (chloride + bicarbonate)
• Normal Anion Gap– Hyperchloremic acidosis– GI or renal Loss of
bicarbonate– Impaired renal acid
secretion– Reabsorption of Chloride– Examples:
• Diarrhea• Renal Tubular Acidosis• Carbonic Anhydrase
Inhibition
• High Anion Gap– Acid retention– Examples:
• Lactic Acidosis: most common
• Ketoacidosis• Advanced Renal Failure• Drug and Toxin Induced
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