“Technology for a better future”

Biotechnology is the application of technological innovation as it pertains to biological and life sciences.

Nanobiotechnology incorporates biotechnology on the nano-scale.

IntroductionSize Ranges of Biological Material

•Cells: 100um – 10um

•Cell organelles (nucleus, mitochondrion): 10um –1um

•Viruses: 100nm- 50nm

•Cell material (proteins, lipids, DNA, RNA): 10nm – 0.1nm

IntroductionNanobiotechnology is an emerging field

•Cells discovered 1665 •Electron microscope 1950s•Watson and Crick discover DNA double helix 1953•Mapping of Human Genome 2003

Where is Nanobiotechnology going? Applications?

•Neurological functions of the brain •Cell structure and physiology •Virus Detection•Radiation/Chemotherapy •Drug delivery•Neurological functions of the brain •Utilization of imaging devices

Brain-Machine InterfaceBrain-machine interface (BMI) is a fabricated

system to interpret voluntary brain activity

and convert to a mechanical movement

• Physiology:Electrical signals in brain → spinal cord → skeletal muscle

• BMI needed for individuals with:spinal cord injury, or Parkinson’s disease

Brain-Machine InterfaceProcedures involved:

1) mapping of brain target specific neurons

2) electrode implantation

3) signal acquisition

4) wireless transmission

5) signal processing

6) mechanical action

Study of DNADNA molecules, under the influence of an electric field, are

forced through nano-scale channels (~100 nm) on a “gel

biochip”. The molecules deform and stretch to pass

through the small channels.

• This process separates DNA fragments by length. This is part of the method used to sequence the DNA in the human genome and in identifying a unique DNA “fingerprint”.

Nanomechanical OscillatorA nano-scale cantilevered beam can be used to detect the

presence of viruses and bacteria and find their masses.

• The beam can be coated with antibodies specific to a particular virus and then put into a substance to attract that virus. The oscillation of the beam can then be measured and compared to the oscillation before exposure to the substance.

Imaging Devices Atomic Force

Microscopy (AFM)

• Scanning Tunneling

Microscopy (STM)

Imaging DevicesAFM and STM are used for better resolution of nano-particles.

Analysis includes bacteria and protein structure, force measurements within particles, and virus-host interactions.

Nano Medicine Nanosilver:-

Using the nano crystalineform of Silver to fight against Bacteria

Regenerating Neurons:-

Creating artificial neurons to take over the functions of real motor neurons

Targeting Cancer Nano particles generate

supersonic shock waves to target Cancer.

Photodynamic Therapy.

Monitor post treatment relaps.

Lets use this blessings of science for greater benefit of mankind…………….a sufferings free human race!