By Salehe Sekandari

Connective tissueConnective tissue, as the name implies,

forms a continuum with epithelial tissue ,muscle, and nervous tissue to

maintain a functionally integrated body.

Unlike cells of Epithelial tissue, connective tissue cells are not directly attached to one another.

Connective tissue consists of individual cells scattered within an extracellular matrix.

Major Functions of Connective TissueConnection of body tissuesProtection of organsStorage of energyDiffusion of metabolitesDefenceCell growth and differentiationWound healing

Connective tissue elementsCellsFibersGround substance

Extracellular matrix

cellsFibroblasts (which secrete the fibers and

ground substance of the extracellular matrix).Macrophages (which ingest and remove

foreign material or damaged cells). Plasma cells(Which derived from B

lymphocytes and manufacture antibodies. Adipocytes (which store fat). Mast cells (which trigger inflammation).Mesenchymal cells

lymphocytes, Eosinophils, and neutrophils

FIBROBLAST VS FIBROCYTE

Collagen Fibers

Elastic Fibers

Reticular Fibers

Elastic

Collagen

Ground substance Components: Glycosaminoglycans

dermatan sulfate, keratan sulfate, Heparan sulphate, chondroitin sulfate, hyaluronic acid

Glycoproteins Laminin, Fibronectin, Chondronectin,

Osteonectin

Tissue Fluid

Connective Tissue:a-Loose CT b-Dense(regular & Irregular) CTC-Mucous CTD-Mesenchymal CTE-Reticular CTF-Adipose CT(unilocular(white) &

Multilocular(brown))G-Elastic CTH-CartilageI-BoneJ-BloodK-Lymph

Loose connective tissueLoose connective tissueLoose

arrangement of fibers and cells in abundant ground substance

Underlies all epithelia, between muscles, passageways for nerves and blood vessels

5-13

Dense Irregular Connective TissueDense Irregular Connective Tissue

Densely packed, randomly arranged, collagen fibers and few visible cells reticular layer of derm; capsules around organs

5-14

Dense Regular Connective TissueDense Regular Connective Tissue

Densely, packed, parallel collagen fibers compressed fibrobalast nuclei

Tendons and ligaments hold bones together and attach muscles to bones

5-15

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1. Hyaline cartilage2. Elastic cartilage

3. Fibrocartilage

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Compact Bone

Spongy Bone

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Histology of Bone Tissue

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Compact BoneCompact BoneGround sectionGround section

(Canal of volkman)

Compact BoneCompact BoneGround sectionGround section

Thanks for your attention!