Boletín Nanomedicina marzo 2011

NanomedicinaBoletín

generado por VIGIALE, IALE Tecnología.

Marzo 2011

INDICE

NOTICIAS

HIDDEN TEXT TO MARK THE BEGINNING OF THE TABLE OF CONTENTS

1. Nanohybrid materials: small is powerful 2

2. German risk institute publishes opinion on cancer risk from nanomaterials 2

3. New nanotechnology increases the efficacy of medicines 2

4. Tiny gems take big step in battling cancer 2

5. Gene fuelled transporter causes breast cancer cells to self-destruct 2

6. Microbubbles to light the way to sentinel lymph nodes of breast cancer patients 3

7. Nanotechnology may lead to new treatment of liver cancer 3

8. Silk moth's antenna inspires new nanotech tool with applications in Alzheimer's research 3

9. Gen que provoca la auto-destrucción de las células de cáncer de mama 3

10. Advancell y Leitat crean la nueva sociedad ReadyCell 4

11. Un mejor disco para la reparación de la columna 4

12. Worlds first program for research physicians in nanoscale medicine 4

13. World's most powerful optical microscope: microscope could 'solve the cause of viruses' 4

14. Important funding for nanomedicine research to improve diagnosis and treatment 5

15. EUMINAfab opens 4th Call 5

16. Cualificación clave en Nanotecnología 5

17. Tres millones de euros para dos proyectos de investigación de la UZ 5

18. Un marcapasos del tamaño de una pastilla Tic Tac 6

19. Un medicamento sigue al melanoma allá donde vaya 6

20. Nanoscience researchers develop new gene detection system 6

21. Catch Cancer: Now nano-technology can help us detect cancers in a jiffy 6

22. Waging war on infectious diseases 6

23. 'Nano-Velcro' Technology used to improve capture of circulating cancer cells 7

24. Un detector de cáncer de una hora 7

PATENTES 25. Patentes publicadas este mes 7

26. Origen de los principales actores del mes 8

27. Principales temas tratados en las patentes del mes 8

28. Principales titulares de las patentes del mes 9

29. Principales inventores que patentaron este mes 9

30. WO2011034570A1: Diagnostic and therapeutic nanoparticles 10

31. WO2011035279A2: Nanocarriers for imaging and therapy applications 10

32. US7910086: Nanoparticles for protein drug delivery 10

33. US20110071493A1: Flow-Induced delivery from a drug mass 10

34. US20110070153A1: Artificial cells 10

INDICE 35. US20110071428A1: Biopsy device 11

36. US20110070202A1: Targeted delivery to the brain of magnetically labeled stem cells 11

37. US20110071091A1: Injectable aqueous ophthalmic composition and method of use therefor 11

38. US20110070205A1: Multipotent stem cells and uses thereof 11

39. US20110071509A1: Method for modifying the refractive index of ocular tissues 12

40. WO2011015226A1: Process for preparation of sterile powdered pharmaceutical compound 12

41. US20110038942A1: Beta-lactoglobulin-polysaccharide for hydrophobic bioactive compound 12

42. US7914781: Compositions for inhibiting atherosclerosis 12

43. US20110071629A1: Filtering polymers for ophthalmic applications 13

44. US20110064810A1: Tissue engineering method for organ reconstruction 13

45. US20110066219A1: Conducting polymer nanowire brain-machine 13

EVENTOS, CURSOS YSEMINARIOS 46. NanoManufacturing Conference & Exhibits 13

47. NanoOstrava 2011 14

48. Nanomedicine 2011 - 3rd ESF Summer School 14

49. INRS Occupational Health Research Conference 2011 14

50. Nanotubes and Nanocomposites 2011 14

51. ImagineNano 14

52. NanoManufacturing Conference & Exhibits 15

53. 5th Concertation and Consultation Workshop on Micro-Nano-Bio convergence Systems 15

54. Greener Nano 2011 15

55. EuroNanoForum 2011 in partnership with Nanotech Europe 15

56. Summer School on "Plasmonics, Functionalization and Biosensing" 16

57. European Perspectives in Personalised Medicine 16

ARTÍCULOS-CIENTÍFICOS 58. Artículos científicos publicados este mes 16

59. Principales temas tratados en los artículos científicos del mes 17

60. Principales entidades con publicaciones este mes 17

61. Principales investigadores que publicaron este me 18

62. Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica... 18

63. Hydroxycamptothecin-loaded nanoparticles induce human lung cancer cell apoptosis 18

64. High sensitivity nanoparticle detection using optical microcavities 19

65. Imaging of tat protein transduction domain in living cells 19

INDICE 66. Progesterone activates the principal Ca2+ channel of human sperm 19

67. In vivo study of dendron-like nanoparticles for stem cells "tune-up": From nano to tissues. 19

68. Prokineticin Receptor 1 Antagonist PC-10 as a Biomarker for Imaging Inflammatory Pain 19

69. Live-cell visualization of dynamics of HIV budding site interactions with an ESCRT component 20

70. Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes.. 20

71. Membrane nanotubes induced by aqueous phase separation and stabilized ... 20

72. A synthetic enzyme inhibitor is a novel targeting ligand for nanotherapeutic drug delivery.. 20

73. Ordered assembly of murine leukemia virus capsid protein.. 21

74. Creating favorable geometries for directing organic photoreactions 21

75. One pot synthesis of ZnSCu nanoparticles using biocompatible L-Cysteine as stabilser... 21

76. DNA damage in embryonic stem cells caused by nanodiamonds 21

77. How to detect a dwarf - in vivo imaging of nanoparticles in the lung 22

78. May nanoparticle systems play a role in the treatment of cerebral gliomas? 22

79. Excellent biocompatibility of semiconductor quantum dots ... 22

80. Squalenoyl gemcitabine nanomedicine... therapy in pancreatic cancer 22

81. Statistical analysis of nanoparticle dosing in a dynamic cellular system 23

82. Progress and challenges in quantifying skin permeability to nanoparticles using a quantum dot..... 23

83. Photothermal response of human and murine cancer cells to multiwalled carbon nanotubes 23

84. Cytotoxicity and oxidative stress induced by different metallic nanoparticles 23

NORMATIVAS 85. EuroNanoMed: Ayudas para proyectos de investigación en nanomedicina 24

86. Programa Nacional de Internacionalización de la I+D: Eurociencia, Eurosalud, FCCI, BOI, Euroinv... 24

87. Resolución para la construcción del Centro Andaluz de Nanomedicina y Biotecnología (BIONAND) 24

INFORMES Y OTRASPUBLICACIONES 88. Medical Imaging Markets 25

89. Unravelling Single Cell Genomics Micro and Nanotools 25

90. Linking Biomedical Informatics, Grid Computing and Nanomedicine 25

91. Nanotechnology Interviews Podcasts: NANOCYL 25

92. La nanotecnología, una ciencia que aporta valor a las exportaciones irlandesas 26

93. The Future of Nanomedicine in Surgery Predicted 26

94. NIOSH seeks public input to update its nanotechnology strategic plan 26

95. Nanotechnology in Medicine 26

96. Nanobiotechnology 26

NanomedicinaNOTICIAS

Nanohybrid materials: small is powerfulPublicada el 03/15/2011.

Medical diagnostics, airport security, and personal health kits all require more selective and more sensitive diagnosticdevices. Researchers in Nebraska are pursuing nanohybrid materials which hold tremendous potential in this regard.

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German risk institute publishes opinion on cancer risk fromnanomaterialsPublicada el 03/15/2011.

The German Federal Institute for Risk Assessment (BfR) has published its current opinion on the cancer risk ofnanomaterials and nanoparticles released from products.

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New nanotechnology increases the efficacy of medicinesPublicada el 03/15/2011.

Technology has been developed within Top Institute Pharma that helps medicines be absorbed quicker into the bloodand thus be more effective.

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Tiny gems take big step in battling cancerPublicada el 03/15/2011.

Dean Ho, an associate professor of biomedical engineering and mechanical engineering at Northwestern University,believes a tiny carbon particle called a nanodiamond may offer an effective drug delivery solution for hard-to-treatcancers.

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Gene fuelled transporter causes breast cancer cells to self-destruct

Marzo 2011 Página 2

NanomedicinaPublicada el 03/15/2011.

Scientists at Queens University Belfast have shown that they can deliver a gene directly into breast cancer cellscausing them to self-destruct, using an innovative, miniscule gene transport system, according to research publishedtoday (28 February) in the International Journal of Pharmaceutics.

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Microbubbles to light the way to sentinel lymph nodes of breastcancer patientsPublicada el 03/15/2011.

Researchers at the University of California, San Diego are developing nonsurgical methods for identifying criticallymph nodes to help doctors determine courses of treatment for breast cancer patients. The sentinel lymph node isroutinely biopsied or removed and dissected to determine the likelihood that the cancer has spread beyond thebreast.

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Nanotechnology may lead to new treatment of liver cancerPublicada el 03/15/2011.

Nanotechnology may open a new door on the treatment of liver cancer, according to a team of Penn State College ofMedicine researchers. They used molecular-sized bubbles filled with chemotherapy drugs to prevent cell growth andinitiate cell death in test tubes and mice.

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Silk moth's antenna inspires new nanotech tool with applications inAlzheimer's researchPublicada el 03/15/2011.

By mimicking the structure of the silk moth's antenna, University of Michigan researchers led the development of abetter nanoporea tiny tunnel-shaped tool that could advance understanding of a class of neurodegenerative diseasesthat includes Alzheimer's.

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Gen que provoca la auto-destrucción de las células de cáncer demama



Científicos de la Queens University de Belfast han demostrado que pueden ofrecer un gen directamente en lascélulas de cáncer de mama haciendo que se autodestruyan, utilizando un innovador sistema de transporte minúsculogen, según una investigación publicada 28 de febrero en el Diario Internacional de Farmacia.

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Advancell y Leitat crean la nueva sociedad ReadyCellPublicada el 03/15/2011.

La creación de Readycell abre un nuevo ciclo para Advancell, que traspasará a Leitat su know how y su tecnologíade servicios y reactivos celulares, y focalizará su estrategia en la división de nanomedicina y desarrollo de fármacos.

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Un mejor disco para la reparación de la columnaPublicada el 03/15/2011.

Unos implantes cultivados a partir de células vivas podrían ofrecer mejor soporte y flexibilidad. Un nuevo tipo dedisco de reemplazo -que consiste en una prótesis sembrada con células vivas- podría aliviar el dolor de espalda, sinmuchos de los efectos secundarios causados por las soluciones quirúrgicas.

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Worlds first program for research physicians in nanoscale medicine

Publicada el 03/15/2011.

The College of Nanoscale Science and Engineering (CNSE) of the University at Albany and SUNY DownstateMedical Center (Downstate) announced the establishment of a first-of-its-kind, dual degree program to provide world-class education and training in both medicine and nanoscale science and engineering.

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World's most powerful optical microscope: microscope could 'solvethe cause of viruses'Publicada el 03/15/2011.

Scientists have produced the world's most powerful optical microscope, which could help us to understand thecauses of many diseases. Writing in the journal Nature Communications, the team have created a microscope whichshatters the record for the smallest object the eye can see, beating the diffraction limit of light.


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Important funding for nanomedicine research to improve diagnosisand treatmentPublicada el 03/15/2011.

Seven new research projects on regenerative medicine and nanomedicine received $16 million in funding. Thestudies, co-funded by the Canadian Institutes of Health Research (CIHR) and the Canadian Space Agency (CSA).

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EUMINAfab opens 4th CallPublicada el 03/15/2011.

The European Research Infrastructure for multimaterial micro and nano fabrication and characterisation opens the4th call for no fee access to 36 installations containing equipment to high and micro and nano technologies.

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Cualificación clave en NanotecnologíaPublicada el 03/15/2011.

La Universidad de Tecnología de Vienna, la Universidad de Recursos Naturales y Ciencias Aplicadas de Viena, yDanube University Krems han desarrollado un programa de master en nanociencias y nanomedicina. El cursocomenzará en el otoño de 2011.

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Tres millones de euros para dos proyectos de investigación de laUZPublicada el 03/15/2011.

Dos proyectos liderados por la Universidad de Zaragoza (UZ): Uno de ellos es el proyecto TRAIN2 para laconsolidación del sudoeste europeo como foco de excelencia en nanociencia y nanotecnología, y el otro es eldenominado CliNK, de inmunoterapia, para conseguir una mejor activación de las células "asesinas" contra lostumores hematológicos.

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NanomedicinaUn marcapasos del tamaño de una pastilla Tic TacPublicada el 03/15/2011.

Medtronic, el mayor fabricante mundial de dispositivos médicos, está usando la microelectrónica y la fabricación dechips para reducir el tamaño de los marcapasosdispositivos implantados que regulan el ritmo cardíaco.

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Un medicamento sigue al melanoma allá donde vayaPublicada el 03/15/2011.

Varios investigadores están probando la seguridad de una nanopartícula dirigida a las células cancerígenas.

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Nanoscience researchers develop new gene detection systemPublicada en BSI -Nanotechnology news, 03/15/2011.

Researchers in the US have employed nanotechnology to improve the detection of a mutation that has been linked toaround 90 per cent of pancreatic cancers.

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Catch Cancer: Now nano-technology can help us detect cancers ina jiffyPublicada en Nanotechnology Now, 03/15/2011.

Scientists from the Harvard Medical School and the Massachusetts General Hospital (MGH) have developed ahandheld device that can detect gastric cancers in one hour with 96 per cent accuracy.

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Waging war on infectious diseasesPublicada en Nanotechwire.com - Bio/Medicine, 03/15/2011.

A new line of defence has been established against global health problems and infectious diseases, with the officialopening of the Australian Infectious Diseases Research Centre in Brisbane.

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Nanomedicina'Nano-Velcro' Technology used to improve capture of circulatingcancer cellsPublicada en Science Daily - Nanomedicina, 03/15/2011.

Now, a UCLA research team has developed an innovative device based on Velcro-like nanoscale technology toefficiently identify and "grab" these circulating tumor cells, or CTCs, in the blood.

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Un detector de cáncer de una horaPublicada en Technology Review, 03/15/2011.

Un dispositivo que se conecta a un teléfono inteligente permite a los médicos diagnosticar el cáncer desde la camadel paciente.

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PATENTES

Patentes publicadas este mesPublicada el 04/01/2011.

Fuente: Espacenet, USPTO


NanomedicinaOrigen de los principales actores del mesPublicada el 04/01/2011.

Fuente: Espacenet, USPTO

Principales temas tratados en las patentes del mesPublicada el 04/01/2011.

Fuente: Espacenet, UPSTO


NanomedicinaPrincipales titulares de las patentes del mesPublicada el 04/01/2011.

Fuente: Espacenet, UPSTO

Principales inventores que patentaron este mesPublicada el 04/01/2011.

Fuente: Especenet, USPTO


NanomedicinaWO2011034570A1: Diagnostic and therapeutic nanoparticlesPublicada el 03/31/2011.

Inventor: Gobin Andre M (US). Titular: Univ Louisville Res Found (US). Resumen: More particularly, the presentinvention relates to creating a hybrid gold / gold sulfide nanoparticle with a chitosan matrix surrounding the metallicnanoparticle and a method for making the same.

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WO2011035279A2: Nanocarriers for imaging and therapyapplicationsPublicada el 03/31/2011.

Inventor: Eelianov Sanislav. Titular: Texas Univ (US). Resumen: Nanocarriers and methods of preparation and use ofnanocarriers are presented..

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US7910086: Nanoparticles for protein drug deliveryPublicada el 03/31/2011.

Inventor: Sng Hing-Wn.Titulares: GP Medical Inc (US); Nat Univ Tsinghua (TW). Resumen: The invention discloses apharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactiveagent for oral delivery.

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US20110071493A1: Flow-Induced delivery from a drug massPublicada el 03/31/2011.

Inventor: Lobl Thomas J (US). Titular: Neurosystec Corp (US). Resumen: Drug solutions (or other combinations ofvehicle with entrained drug) are prepared by removing drug from one or more masses of a solid form of the drug.

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US20110070153A1: Artificial cellsPublicada el 03/31/2011.

Inventor: Hyde Roderick A. Titular: Searete Llc (US). Resumen: The present disclosure relates to variousembodiments associated with artificial cells, particularly artificial antigen presenting cells, methods of making thesame, methods of administering the same.



US20110071428A1: Biopsy devicePublicada el 03/31/2011.

Inventor: Frecker Mary. Titular: Penn State Res Found (US). Resumen: Inventive biopsy devices can be usedthrough an endoscope channel to perform zero invasive biopsies on the gastrointestinal system and other organs.

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US20110070202A1: Targeted delivery to the brain of magneticallylabeled stem cellsPublicada el 03/31/2011.

Inventor y Titular: Yarowsky Paul (US). Resumen: Provided herein is a method of targeting stem cells to a specificregion of the central nervous system of an individual in need of such treatment...

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US20110071091A1: Injectable aqueous ophthalmic composition andmethod of use thereforPublicada el 03/31/2011.

Inventor y Titular: Chowhan Masood A. (US). Resumen: The present invention is directed to the provision of anophthalmic composition suitable for intravitreal injection.

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US20110070205A1: Multipotent stem cells and uses thereofPublicada el 03/31/2011.

Inventor: Crawford Keith. Titular: Brigham & Womens Hospital (US). Resumen: The invention provides a quiescentstem cell having the capacity to differentiate into ectoderm, mesoderm and endoderm, and which does not expresscell surface.

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NanomedicinaUS20110071509A1: Method for modifying the refractive index ofocular tissuesPublicada el 03/31/2011.

Inventor: Knox Wayne H. Titular: Univ Rochester (US). Resumen: A method for providing vision correction to apatient. The method includes: (a) measuring the degree of vision correction; (b) directing and focusing femtosecondlaser; and (c) scanning the laser pulses across a volume of the cornea or the lens.

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WO2011015226A1: Process for preparation of sterile powderedpharmaceutical compoundPublicada el 03/15/2011.

Inventor: De Tommaso Vincenzo. Titular: Pharmatex Italia Srl (IT). Resumen: Process for the preparation of a sterilepowdered pharmaceutical compound. The invention is also directed to triamcinolone acetonide according to thisprocess.

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US20110038942A1: Beta-lactoglobulin-polysaccharide forhydrophobic bioactive compoundPublicada el 03/15/2011.

Inventor: Livney Yoav D. Titular: Technion Res & Dev Foundation (IL). Resumen: The present invention providescolloidally stable dispersions of nanoparticles comprising beta-lactoglobulin and a polysaccharide which aretransparent when diluted in aqueous media.

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US7914781: Compositions for inhibiting atherosclerosisPublicada el 03/15/2011.

Inventor y Titular: Higuchi Maira de Lourdes (BR). Resumen: The present invention relates to compositions andmethods for the reduction of atherosclerotic plaques and the decrease in the level of total serum cholesterol,triglycerides, serum LDL cholesterol, and serum HDL cholesterol.

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NanomedicinaUS20110071629A1: Filtering polymers for ophthalmic applications


Inventor: Mentak Khalid. Titular: Key Medical Technologies Inc (US). Resumen: Opthalmic devices, particularlyintraocular lenses (IOL), with improved contrast sensitivity and methods of making same.

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US20110064810A1: Tissue engineering method for organreconstructionPublicada el 03/15/2011.

Inventor y Titular: Ghanavi Jalaledin (IR). Resumen: The various embodiments herein relate to an injectable matrixused for regeneration, reconstruction, repair or replacement of organ or tissue.

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US20110066219A1: Conducting polymer nanowire brain-machinePublicada el 03/15/2011.

Inventor: Llinas Rodolfo R (US). Titular: Univ New York (US). Resumen: The present invention relates to conductingpolymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive.

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EVENTOS, CURSOS Y SEMINARIOS

NanoManufacturing Conference & ExhibitsPublicada el 03/15/2011.

This conference will highlight the current, near-term, and future applications of nanotechnology and how they aretransforming the way we manufacture products.Fecha: April 05 - 06, 2011. Lugar: Drury Lane Conference Center, USA.

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NanomedicinaNanoOstrava 2011Publicada el 03/15/2011.

The meeting is a platform to facilitate open discussions between scientists, students and representatives fromcompanies with a vested interest in furthering the development of nanomaterials and nanotechnology.Fecha: Apr 27 - 29, 2011Lugar: Ostrava PORUBA, Czech Republic.

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Nanomedicine 2011 - 3rd ESF Summer SchoolPublicada el 03/15/2011.

The ESF Summer School Nanomedicine 2011, has been designed to provide an intensive state-of the- art trainingacross all of the sub-disciplines of Nanomedicine, and to foster discussion and exchange of ideas in a relaxedatmosphere.Fecha: June 19-24, 2011. Lugar: Wittenberg, Germany.

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INRS Occupational Health Research Conference 2011Publicada el 03/15/2011.

Occupational Health Research Conference 2011: Risks associated to Nanoparticles and Nanomaterials.Fecha: 05 - 07 April 2011. Lugar: Nancy, France.

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Nanotubes and Nanocomposites 2011Publicada el 03/15/2011.

Will focus on research and development in all nano-particles, polymer processing and application, as well as marketdirection, growth and potential for commercialisation.Fecha: April 06 - 07, 2011. Lugar: Le Meridien Brussels, Belgium.

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ImagineNano



Extensive thematic conferences will be held in parallel and a huge industrial exhibition carried out with the latestnanotrends for the future.Fecha: Apr 11 - 14, 2011. Lugar: Bilbao, Spain.

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NanoManufacturing Conference & ExhibitsPublicada el 03/15/2011.

This conference will highlight the current, near-term, and future applications of nanotechnology and how they aretransforming the way we manufacture products.Fecha: Apr 05 - 06, 2011. Lugar: Oakbrook Terrace (Chicago) IL, EE.UU.

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5th Concertation and Consultation Workshop on Micro-Nano-Bioconvergence SystemsPublicada el 03/15/2011.

Co-organized by the European Commission and IKERLAN-IK4 a private not-profit Technological Research Centre inthe north of Spain.Fecha: April 05 - 06, 2011. Lugar: Mondragón, Spain.

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Greener Nano 2011Publicada el 03/15/2011.

We will focus on two key research areas: highlight state-of-the-art in materials synthesis and characterizationchallenges, and discuss biological impacts of nanotechnology.Fecha: May 01 - 03, 2011. Lugar: Cupertino California, USA

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EuroNanoForum 2011 in partnership with Nanotech EuropePublicada el 03/15/2011.

EuroNanoForum is a biannual event supported by the European Commission and organised within the framework ofthe Presidency of the European Union.Fecha: May 30 - June 01, 2011. Lugar: Budapest, Hungary.

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NanomedicinaSummer School on "Plasmonics, Functionalization and Biosensing"Publicada el 03/15/2011.

The Summer School Plasmonics, Functionalization and Biosensing is part of the FP7 Collaborative projectNanoantenna program.Fecha: 24 April - 30 April 2011. Lugar: Kirchoff Institute in Heidelberg, Germany.

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European Perspectives in Personalised MedicinePublicada el 03/15/2011.

This conference will bring together key stakeholders of the research community and the healthcare sector to identifythe developments needed in order to contribute to the research for Personalised Medicine.Fecha: 12-13 May 2011. Lugar: Square-Brussels Meeting Centre, Brussels

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ARTÍCULOS-CIENTÍFICOS

Artículos científicos publicados este mesPublicada el 04/01/2011.

Fuente: Scopus

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NanomedicinaPrincipales temas tratados en los artículos científicos del mesPublicada el 04/01/2011.

Fuente: Scopus

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Principales entidades con publicaciones este mesPublicada el 04/01/2011.

Fuente: Scopus


NanomedicinaPrincipales investigadores que publicaron este mePublicada el 04/01/2011.

Fuente: Scopus

Systemic distribution, nuclear entry and cytotoxicity of amorphousnanosilica...Publicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 03/29/2011.

Autor: Nabeshi H. Resumen: The present study was designed to examine the skin penetration, cellular localization,and cytotoxic effects of the well-dispersed amorphous silica particles of diameters ranging from 70 nm to 1000 nm.

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Hydroxycamptothecin-loaded nanoparticles induce human lungcancer cell apoptosisPublicada en Nanomedicine Research Publicaciones, 03/29/2011.

Autor: Zhang G. Resuemn: 10-Hydroxycamptothecin (HCPT) elicits strong anti-cancer effects and is less toxicmaking it widely used in recent clinical trials. However, its low solubility limits its application as an effective anti-cancer therapy.

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NanomedicinaHigh sensitivity nanoparticle detection using optical microcavitiesPublicada el 03/25/2011.

Autor: Tao Lu. Resumen: We demonstrate a highly sensitive nanoparticle and virus detection method by using athermal-stabilized reference interferometer in conjunction with an ultrahigh-Q microcavity.

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Imaging of tat protein transduction domain in living cellsPublicada en Nanomedicine Research Publicaciones, 03/23/2011.

Autor: Junji Imamura. Resumen: This work should guide the future design of TatP-based peptides as therapeuticnanocarriers with efficient transduction.

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Progesterone activates the principal Ca2+ channel of human sperm


Autor: Lishko PV. Resumen: Steroid hormone progesterone released by cumulus cells surrounding the egg is apotent stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them penetrate the egg'sprotective vestments.

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In vivo study of dendron-like nanoparticles for stem cells "tune-up":From nano to tissues.Publicada el 03/16/2011.

Autor: Oliveira JM. Resumen: The control of stem cell differentiation to become osteoblasts in vivo is still regarded asa challenge in stem cell-based and bone tissue engineering strategies. Biodegradable dexamethasone-loadeddendron-like nanoparticles of carboxymethylchitosan/poly(amidoamine) dendrimer have been proposed asintracellular drug delivery systems of bioactive molecules.

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Prokineticin Receptor 1 Antagonist PC-10 as a Biomarker forImaging Inflammatory Pain



Autor:Jacobson O. Resumen: Prokineticin receptor 1 (PKR1) and its ligand Bv8 were shown to be expressed ininflammation-induced pain and by tumor-supporting fibroblasts. Blocking this receptor might prove useful for reducingpain and for cancer therapy. However, there is no method to quantify the levels of these receptors in vivo.

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Live-cell visualization of dynamics of HIV budding site interactionswith an ESCRT componentPublicada el 03/15/2011.

Autor:V ärtel. Resumen: HIV diverts the cellular ESCRT. The ESCRT consists of four heteromeric complexes(ESCRT-0 to ESCRT-III), which mediate different membrane abscission processes, most importantly formation ofintralumenal vesicles at multivesicular bodies.

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Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes..Publicada el 03/15/2011.

Autor: R Lande. Resumen: Systemic lupus erythematosus (SLE) is a severe and incurable autoimmune diseasecharacterized by chronic activation of plasmacytoid dendritic cells (pDCs) and production of autoantibodies againstnuclear self-antigens by hyperreactive B cells.

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Membrane nanotubes induced by aqueous phase separation andstabilized ...Publicada el 03/15/2011.

Autor: Y Li. Resumen: Tubular membrane structures are widespread in eukaryotic cells, but the mechanismsunderlying their formation and stability are not well understood. Previous work has focused on tube extrusion fromcells and model membranes under the application of external forces.

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A synthetic enzyme inhibitor is a novel targeting ligand fornanotherapeutic drug delivery..



Autor: Liao D. Resumen: Unresolved problems associated with ligand-targeting of liposomal nanoparticles (NPs) tosolid tumors include variable target receptor expression due to genetic heterogeneity and insufficient target specificityleading to systemic toxicities.

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Ordered assembly of murine leukemia virus capsid protein..Publicada el 03/15/2011.

Autor: Hilditch L. Resumen: The restriction factor Fv1 confers resistance to murine leukemia virus (MLV), blockingprogression of the viral life cycle after reverse transcription, but before integration into the host chromosome. It isknown that the specificity of restriction is determined by both the restriction factor and the viral capsid (CA)...

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Creating favorable geometries for directing organic photoreactions

Publicada en Nanomedicine Research Publicaciones, 03/15/2011.

Autor: M Kim. Resumen: The products of photoreactions of conjugated organic molecules may be allowed byselection rules but not observed in solution reactions because of unfavorable reaction geometries.

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One pot synthesis of ZnSCu nanoparticles using biocompatible L-Cysteine as stabilser...Publicada en Journal of Nanotechnology and Its Apliccations, 03/15/2011.

Autor: Ashish Tiwari. Resumen: ZnS:Cu nanoparticles were prepared by facile one pot synthesis using biocompatibleL-Cysteine (L-Cys) as stabilizing agent. X-ray diffraction (XRD), scanning electron microcopy (SEM), energydispersive spectrum (EDS), fourier transform infrared spectroscopy (FTIR) was used to characterize thenanoparticles.

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DNA damage in embryonic stem cells caused by nanodiamonds


NanomedicinaPublicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 03/15/2011.

Autor: Xing Y. Resumen: In this study, the authors report the first genotoxicity study on nanodiamonds (NDs) byincubating embryonic stem cells with NDs and evaluating the expression of DNA repair proteins, such as p53 andMOGG-1.

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How to detect a dwarf - in vivo imaging of nanoparticles in the lung


Autor: Roller J. Resumen: The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPsmay intentionally be delivered into the lung as contrast agents and drug delivery systems.

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May nanoparticle systems play a role in the treatment of cerebralgliomas?Publicada el 03/15/2011.

Autor: Caruso G. Resumen: The nanoparticle has emerged as a potential vector for brain delivery, able to overcomethe difficulties of modern strategies. Moreover, multifunctionality can be engineered into a single nanoplatform so thatit can provide tumor-specific detection, treatment, and follow-up monitoring. This review reports the latest research innanoparticle-based glioma treatment.

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Excellent biocompatibility of semiconductor quantum dots ...Publicada el 03/15/2011.

Autor: Somesree GhoshMitra. Resumen: However, toxicity of these nanostructures in the intracellular environmenthas prevented a biomedical breakthrough.

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Squalenoyl gemcitabine nanomedicine... therapy in pancreaticcancerPublicada el 03/15/2011.

Autor: Soukaina R. Resumen: Development of chemoresistance and rapid inactivation of gemcitabine, the standardtherapy for advanced pancreatic cancer, are responsible of the major therapeutic failures. To overcome the abovedrawbacks we designed a novel nanomedicine strategy for gemcitabine nanoparticle formulation based on squaleneconjugation.



Statistical analysis of nanoparticle dosing in a dynamic cellularsystemPublicada el 03/15/2011.

Autor: Summers HD. Resumen: In this paper, the authors investigate probabilities for nanoparticle uptake in cellsusing statistical analysis techniques of nanoparticle-loaded endosomes.

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Progress and challenges in quantifying skin permeability tonanoparticles using a quantum dot...Publicada en International Council on Nanotechnology - Virtual Journal, 03/14/2011.

Autor: Mortensen LJ. Resumen: This paper reviews common pitfalls or noise factors that can easily complicateinterpretation of results and induce ambiguity in assessing nanoparticle skin penetration risk.

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Photothermal response of human and murine cancer cells tomultiwalled carbon nanotubesPublicada en International Council on Nanotechnology - Virtual Journal, 03/14/2011.

Autor: Fisher JW. Resumen: This study includes an investigation of the degree of intracellular uptake of multiwalledcarbon nanotubes (MWNTs) as part of a larger study of how laser irradiation enhances treatment of cancer cellsthrough enhanced and more controlled thermal deposition, increased tumor injury, and diminished heat shock protein(HSP) expression.

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Cytotoxicity and oxidative stress induced by different metallicnanoparticlesPublicada en International Council on Nanotechnology - Virtual Journal, 03/14/2011.

Autor: Pujalte I. Resumen: The objective of this study, on human renal culture cells, was to assess the toxicity profileof metallic nanoparticles (TiO2, ZnO and CdS) usable in industrial production. Comparative studies were conducted,to identify whether particle properties impact cytotoxicity by altering the intracellular oxidative status.

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Nanomedicina

NORMATIVAS

EuroNanoMed: Ayudas para proyectos de investigación ennanomedicinaPublicada el 03/24/2011.

Hasta el 15 de abril pueden presentarse propuestas a EuroNanoMed, una iniciativa de financiación europea en elmarco del plan ERA-Net de la Comisión Europea destinada a avanzar en la investigación transnacional ennanomedicina.

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Programa Nacional de Internacionalización de la I+D: Eurociencia,Eurosalud, FCCI, BOI, EuroinvestigaciónPublicada el 03/23/2011.

De acuerdo con el Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica, 2008-2011, estaResolución (ayudas) será de aplicación hasta el 31 de diciembre de 2011.

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Resolución para la construcción del Centro Andaluz deNanomedicina y Biotecnología (BIONAND)Publicada el 03/04/2011.

Resolución por la que se hace público el Convenio de colaboración para el Avance de la Biotecnología y laInvestigación Sanitaria (IMABIS), en la selección y ejecución del proyecto «Construcción del Centro Andaluz deNanomedicina y Biotecnología (BIONAND)», cofinanciado por el FEDER.

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NanomedicinaINFORMES Y OTRAS

Medical Imaging MarketsPublicada en Market Research Nano-Medicine 2, 03/29/2011.

The purpose of this TriMark Publications report is to describe the specific market segment of the diagnostics marketsector called medical imaging. Medical imaging can be categorized into nine main modalities: X-ray, ultrasound,computed tomography (CT), positron emission tomography (PET), single photon emission tomography (SPECT),magnetic resonance imaging (MRI), nuclear medicine (NM), mammography and fluoroscopy.

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Unravelling Single Cell Genomics Micro and NanotoolsPublicada en AzoNano - Books, 03/29/2011.

This unique introduction to the growing field of microfluidics applied to genomics provides an overview of the latesttechnologies and emphasizes its potential in answering important biological questions. Written by a physicist and abiologist, it offers a more comprehensive view than the previous literature.

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Linking Biomedical Informatics, Grid Computing and Nanomedicine


The Action-Grid White Paper presents a strategy for developing a new area of research: nano-informatics. This fieldextends Biomedical Informatics to nanomedicine. It was developed in the framework of the EU supported VirtualPhysiological Human project.

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Nanotechnology Interviews Podcasts: NANOCYLPublicada el 03/23/2011.

AZoNano's Cameron Chai speaks to Francis Massin, CEO of Nanocyl. Francis tells us about their plans to install newcarbon nanotube production capabilities that will make them the biggest carbon nanotube producer in the world aswell as their ready to use commercial nanotube-based products.

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NanomedicinaLa nanotecnología, una ciencia que aporta valor a las exportacionesirlandesasPublicada el 03/16/2011.

La nanociencia y la nanotecnología han permitido alcanzar cifras de exportación de un 10% sobre los 150.000millones de bienes y servicios exportados en Irlanda durante el año 2008, según fuentes del sector. Además, seprevé que en los próximos años el crecimiento de dicha industria alcance la cifra de un 20%.

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The Future of Nanomedicine in Surgery PredictedPublicada el 03/16/2011.

A new review published in WIREs Nanomedicine and Nanobiotechnology explores how nanotechnology may providepowerful new tools that could have a marked impact on the therapeutic and diagnostic measures available tosurgeons.

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NIOSH seeks public input to update its nanotechnology strategicplanPublicada el 03/16/2011.

The National Institute of Occupational Safety and Health is seeking public input "on the types of hazard identificationand risk management research that should be considered for updating the NIOSH 2009 nanotechnology strategicplan," the agency announced in a March 7 Federal Register notice.

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Nanotechnology in MedicinePublicada el 03/15/2011.

This report examines the various roles nanotechnology plays in the pharmaceutical industry. The new field ofnanomedicine has a lot of potential and the new advances in this field.

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Nanobiotechnology



This report analyzes the worldwide markets for Nanobiotechnology in US$ Million by the following technologysegments - Nanomaterials (Solid Inorganic Nanoparticles, Nanocomposites, Nanostructured Materials & Membranes,Nanotubes and Fullerenes, & Other Nanomaterials), and Nanodevices/Tools.

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